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Frédéric Carrière
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Research Profile (preview)
Chemicals & Drugs
Anatomy
Genes & Molecular Sequences
Concepts & Ideas
Physiology
Living Beings
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Network (preview)
30
Verger, Robert
21
De Caro, Alain
17
Ferrato, Francine
15
De Caro, Josiane
14
Laugier, René
12
Biochimie et Genie Enzymatique des Lipases, Laboratoire
9
Cambillau, Christian
9
Grandval, Philippe
7
Chahinian, Henri
7
Abousalham, Abdelkarim
7
Aloulou, Ahmed
7
Renou, Christophe
6
Thim, Lars
6
Thirstrup, Kenneth
5
Sias, Barbara
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All Publications
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2009: Amara Sawsan; Lafont Dominique; Fiorentino Brice; Boullanger Paul; Carrière Frédéric; De Caro Alain
Continuous measurement of galactolipid hydrolysis by pancreatic lipolytic enzymes using the pH-stat technique and a medium chain monogalactosyl diglyceride as substrate.
Biochimica et biophysica acta 2009;1791(10):983-90.
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2009: Cavalier Jean-François; Lafont Dominique; Boullanger Paul; Houisse David; Giallo Jacqueline; Ballester Jean-Michel; Carrière Frédéric
Validation of lipolysis product extraction from aqueous/biological samples, separation and quantification by thin-layer chromatography with flame ionization detection analysis using O-cholesteryl ethylene glycol as a new internal standard.
Journal of chromatography. A 2009;1216(37):6543-8.
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2009: Fernandez Sylvie; Chevrier Stéphanie; Ritter Nicolas; Mahler Bruno; Demarne Frédéric; Carrière Frédéric; Jannin Vincent
In vitro gastrointestinal lipolysis of four formulations of piroxicam and cinnarizine with the self emulsifying excipients Labrasol and Gelucire 44/14.
Pharmaceutical research 2009;26(8):1901-10.
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2008: Tuvignon N; Abousalham A; Tocques F; De Caro J; De Caro A; Laugier R; Carrière F
Development of an indirect method for measuring porcine pancreatic lipase in human duodenal fluid.
Analytical biochemistry 2008;383(2):289-95.
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2008: Fernandez Sylvie; Rodier Jean-David; Ritter Nicolas; Mahler Bruno; Demarne Frédéric; Carrière Frédéric; Jannin Vincent
Lipolysis of the semi-solid self-emulsifying excipient Gelucire 44/14 by digestive lipases.
Biochimica et biophysica acta 2008;1781(8):367-75.
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2008: De Caro Josiane; Eydoux Cécilia; Chérif Slim; Lebrun Régine; Gargouri Youssef; Carrière Frédéric; De Caro Alain
Occurrence of pancreatic lipase-related protein-2 in various species and its relationship with herbivore diet.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2008;150(1):1-9.
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2008: Aloulou A; Carrière F
Gastric lipase: an extremophilic interfacial enzyme with medical applications.
Cellular and molecular life sciences : CMLS 2008;65(6):851-4.
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2008: Aloulou A; Puccinelli D; Sarles J; Laugier R; Leblond Y; Carrière F
In vitro comparative study of three pancreatic enzyme preparations: dissolution profiles, active enzyme release and acid stability.
Alimentary pharmacology & therapeutics 2008;27(3):283-92.
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2007: Aloulou Ahmed; Puccinelli Delphine; De Caro Alain; Leblond Yves; Carrière Frédéric
A comparative study on two fungal lipases from Thermomyces lanuginosus and Yarrowia lipolytica shows the combined effects of detergents and pH on lipase adsorption and activity.
Biochimica et biophysica acta 2007;1771(12):1446-56.
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2007: Côtes Karen; Dhouib Rabeb; Douchet Isabelle; Chahinian Henri; de Caro Alain; Carrière Frédéric; Canaan Stéphane
Characterization of an exported monoglyceride lipase from Mycobacterium tuberculosis possibly involved in the metabolism of host cell membrane lipids.
The Biochemical journal 2007;408(3):417-27.
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2007: Eydoux Cécilia; De Caro Josiane; Ferrato Francine; Boullanger Paul; Lafont Dominique; Laugier René; Carrière Frédéric; De Caro Alain
Further biochemical characterization of human pancreatic lipase-related protein 2 expressed in yeast cells.
Journal of lipid research 2007;48(7):1539-49.
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2007: Fernandez Sylvie; Jannin Vincent; Rodier Jean-David; Ritter Nicolas; Mahler Bruno; Carrière Frédéric
Comparative study on digestive lipase activities on the self emulsifying excipient Labrasol, medium chain glycerides and PEG esters.
Biochimica et biophysica acta 2007;1771(5):633-40.
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2007: Aloulou Ahmed; Rodriguez Jorge A; Puccinelli Delphine; Mouz Nicolas; Leclaire Julien; Leblond Yves; Carrière Frédéric
Purification and biochemical characterization of the LIP2 lipase from Yarrowia lipolytica.
Biochimica et biophysica acta 2007;1771(2):228-37.
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2007: Belle Valérie; Fournel André; Woudstra Mireille; Ranaldi Sébastien; Prieri Florence; Thomé Virginie; Currault Julie; Verger Robert; Guigliarelli Bruno; Carrière Frédéric
Probing the opening of the pancreatic lipase lid using site-directed spin labeling and EPR spectroscopy.
Biochemistry 2007;46(8):2205-14.
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2007: Ben Ali Yassine; Carrière Frédéric; Abousalham Abdelkarim
High-level constitutive expression in Pichia pastoris and one-step purification of phospholipase D from cowpea (Vigna unguiculata L. Walp).
Protein expression and purification 2007;51(2):162-9.
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2006: Ben Ali Yassine; Chahinian Henri; Petry Stefan; Muller Günter; Lebrun Régine; Verger Robert; Carrière Frédéric; Mandrich Luigi; Rossi Mosè; Manco Giuseppe; Sarda Louis; Abousalham Abdelkarim
Use of an inhibitor to identify members of the hormone-sensitive lipase family.
Biochemistry 2006;45(47):14183-91.
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2006: Morin Benjamin; Bourhis Jean-Marie; Belle Valérie; Woudstra Mireille; Carrière Frédéric; Guigliarelli Bruno; Fournel André; Longhi Sonia
Assessing induced folding of an intrinsically disordered protein by site-directed spin-labeling electron paramagnetic resonance spectroscopy.
The journal of physical chemistry. B 2006;110(41):20596-608.
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2006: Eydoux Cécilia; Aloulou Ahmed; De Caro Josiane; Grandval Philippe; Laugier René; Carrière Frédéric; De Caro Alain
Human pancreatic lipase-related protein 2: tissular localization along the digestive tract and quantification in pancreatic juice using a specific ELISA.
Biochimica et biophysica acta 2006;1760(10):1497-504.
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2006: Aloulou Ahmed; Rodriguez Jorge A; Fernandez Sylvie; van Oosterhout Dirk; Puccinelli Delphine; Carrière Frédéric
Exploring the specific features of interfacial enzymology based on lipase studies.
Biochimica et biophysica acta 2006;1761(9):995-1013.
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2006: Aloulou Ahmed; Grandval Philippe; De Caro Josiane; De Caro Alain; Carrière Frédéric
Constitutive expression of human pancreatic lipase-related protein 1 in Pichia pastoris.
Protein expression and purification 2006;47(2):415-21.
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2006: Lafont Dominique; Carrière Frédéric; Ferrato Francine; Boullanger Paul
Syntheses of an alpha-D-Gal-(1-->6)-beta-D-Gal diglyceride, as lipase substrate.
Carbohydrate research 2006;341(6):695-704.
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2006: Freie Angela Bourbon; Ferrato Francine; Carrière Frédéric; Lowe Mark E
Val-407 and Ile-408 in the beta5'-loop of pancreatic lipase mediate lipase-colipase interactions in the presence of bile salt micelles.
The Journal of biological chemistry 2006;281(12):7793-800.
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2006: Chahinian Henri; Snabe Torben; Attias Coralie; Fojan Peter; Petersen Steffen B; Carrière Frédéric
How gastric lipase, an interfacial enzyme with a Ser-His-Asp catalytic triad, acts optimally at acidic pH.
Biochemistry 2006;45(3):993-1001.
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2005: Halimi Hubert; De Caro Josiane; Carrière Frédéric; De Caro Alain
Closed and open conformations of the lid domain induce different patterns of human pancreatic lipase antigenicity and immunogenicity.
Biochimica et biophysica acta 2005;1753(2):247-56.
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2005: Carrière Frédéric; Laugier René
Gastrointestinal lipolysis levels and potential use of gastric lipase in pancreatic insufficiency.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(7):715; author reply 716.
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2005: Carrière Frédéric; Grandval Philippe; Gregory Peter C; Renou Christophe; Henniges Friederike; Sander-Struckmeier Suntje; Laugier René
Does the pancreas really produce much more lipase than required for fat digestion?
JOP : Journal of the pancreas 2005;6(3):206-15.
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2005: Ali Yassine Ben; Carrière Frédéric; Verger Robert; Petry Stefan; Muller Günter; Abousalham Abdelkarim
Continuous monitoring of cholesterol oleate hydrolysis by hormone-sensitive lipase and other cholesterol esterases.
Journal of lipid research 2005;46(5):994-1000.
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2005: Petry Stefan; Ben Ali Yassine; Chahinian Henri; Jordan Holger; Kleine Horst; Müller Günter; Carrière Frédéric; Abousalham Abdelkarim
Sensitive assay for hormone-sensitive lipase using NBD-labeled monoacylglycerol to detect low activities in rat adipocytes.
Journal of lipid research 2005;46(3):603-14.
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2005: Carrière Frédéric; Grandval Philippe; Renou Christophe; Palomba Aurélie; Priéri Florence; Giallo Jacqueline; Henniges Friederike; Sander-Struckmeier Suntje; Laugier René
Quantitative study of digestive enzyme secretion and gastrointestinal lipolysis in chronic pancreatitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(1):28-38.
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2005: Sias Barbara; Ferrato Francine; Pellicer-Rubio Maria-Teresa; Forgerit Yvonick; Guillouet Philippe; Leboeuf Bernard; Carrière Frédéric
Cloning and seasonal secretion of the pancreatic lipase-related protein 2 present in goat seminal plasma.
Biochimica et biophysica acta 2005;1686 3():169-80.
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2004: De Caro Josiane; Sias Barbara; Grandval Philippe; Ferrato Francine; Halimi Hubert; Carrière Frédéric; De Caro Alain
Characterization of pancreatic lipase-related protein 2 isolated from human pancreatic juice.
Biochimica et biophysica acta 2004;1701(1-2):89-99.
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2004: Sias Barbara; Ferrato Francine; Grandval Philippe; Lafont Dominique; Boullanger Paul; De Caro Alain; Leboeuf Bernard; Verger Robert; Carrière Frédéric
Human pancreatic lipase-related protein 2 is a galactolipase.
Biochemistry 2004;43(31):10138-48.
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2004: Ben Ali Yassine; Chahinian Henri; Petry Stefan; Muller Günter; Carrière Frédéric; Verger Robert; Abousalham Abdelkarim
Might the kinetic behavior of hormone-sensitive lipase reflect the absence of the lid domain?
Biochemistry 2004;43(29):9298-306.
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2004: Haiker Horst; Lengsfeld Hans; Hadváry Paul; Carrière Frédéric
Rapid exchange of pancreatic lipase between triacylglycerol droplets.
Biochimica et biophysica acta 2004;1682(1-3):72-9.
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2004: Grandval Philippe; De Caro Alain; De Caro Josiane; Sias Barbara; Carrière Frédéric; Verger Robert; Laugier René
Critical evaluation of a specific ELISA and two enzymatic assays of pancreatic lipases in human sera.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2004;4(6):495-503; discussion 503-4.
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2003: Miled N; Berti-Dupuis L; Riviere M; Carrière F; Verger R
In vitro lipolysis by human pancreatic lipase is specifically abolished by its inactive forms.
Biochimica et biophysica acta 2003;1645(2):241-6.
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2002: Chahinian Henri; Bezzine Sofiane; Ferrato Francine; Ivanova Margarita G; Perez Barbara; Lowe Mark E; Carrière Frédéric
The beta 5' loop of the pancreatic lipase C2-like domain plays a critical role in the lipase-lipid interactions.
Biochemistry 2002;41(46):13725-35.
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2002: Ville Eric; Carrière Frédéric; Renou Christophe; Laugier René
Physiological study of pH stability and sensitivity to pepsin of human gastric lipase.
Digestion 2002;65(2):73-81.
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2001: Tiss A; Carrière F; Verger R
Effects of gum arabic on lipase interfacial binding and activity.
Analytical biochemistry 2001;294(1):36-43.
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2001: Carrière F; Renou C; Ransac S; Lopez V; De Caro J; Ferrato F; De Caro A; Fleury A; Sanwald-Ducray P; Lengsfeld H; Beglinger C; Hadvary P; Verger R; Laugier R
Inhibition of gastrointestinal lipolysis by Orlistat during digestion of test meals in healthy volunteers.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(1):G16-28.
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2001: Carrière F; Renou C; Ville E; Grandval P; Laugier R
Advantage of expressing the variations in some digestive parameters as a function of gastric emptying instead of time.
Digestion 2001;64(1):46-53.
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2001: Renou C; Carrière F; Ville E; Grandval P; Joubert-Collin M; Laugier R
Effects of lansoprazole on human gastric lipase secretion and intragastric lipolysis in healthy human volunteers.
Digestion 2001;63(4):207-13.
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2000: El Maarouf H; Carrière F; Rivière M; Abousalham A
Functional expression in insect cells, one-step purification and characterization of a recombinant phospholipase D from cowpea (Vigna unguiculata L. Walp).
Protein engineering 2000;13(11):811-7.
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2000: Miled N; Canaan S; Dupuis L; Roussel A; Rivière M; Carrière F; de Caro A; Cambillau C; Verger R
Digestive lipases: from three-dimensional structure to physiology.
Biochimie 2000;82(11):973-86.
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2000: Carrière F; Renou C; Lopez V; De Caro J; Ferrato F; Lengsfeld H; De Caro A; Laugier R; Verger R
The specific activities of human digestive lipases measured from the in vivo and in vitro lipolysis of test meals.
Gastroenterology 2000;119(4):949-60.
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2000: Chahinian H; Sias B; Carrière F
The C-terminal domain of pancreatic lipase: functional and structural analogies with c2 domains.
Current protein & peptide science 2000;1(1):91-103.
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1999: van Tilbeurgh H; Bezzine S; Cambillau C; Verger R; Carrière F
Colipase: structure and interaction with pancreatic lipase.
Biochimica et biophysica acta 1999;1441(2-3):173-84.
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1999: Bezzine S; Ferrato F; Ivanova M G; Lopez V; Verger R; Carrière F
Human pancreatic lipase: colipase dependence and interfacial binding of lid domain mutants.
Biochemistry 1999;38(17):5499-510.
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1999: De Caro A; Bezzine S; Lopez V; Aoubala M; Daniel C; Verger R; Carrière F
Immunological characterization of digestive lipases.
Methods in molecular biology (Clifton, N.J.) 1999;109():239-56.
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1999: Bezzine S; Ferrato F; Lopez V; de Caro A; Verger R; Carrière F
One-step purification and biochemical characterization of recombinant pancreatic lipases expressed in insect cells.
Methods in molecular biology (Clifton, N.J.) 1999;109():187-202.
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1998: Carrière F; Withers-Martinez C; van Tilbeurgh H; Roussel A; Cambillau C; Verger R
Structural basis for the substrate selectivity of pancreatic lipases and some related proteins.
Biochimica et biophysica acta 1998;1376(3):417-32.
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1998: De Caro J; Carrière F; Barboni P; Giller T; Verger R; De Caro A
Pancreatic lipase-related protein 1 (PLRP1) is present in the pancreatic juice of several species.
Biochimica et biophysica acta 1998;1387(1-2):331-41.
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1998: Roussel A; de Caro J; Bezzine S; Gastinel L; de Caro A; Carrière F; Leydier S; Verger R; Cambillau C
Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations.
Proteins 1998;32(4):523-31.
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1998: Bezzine S; Carrière F; De Caro J; Verger R; De Caro A
Human pancreatic lipase: an exposed hydrophobic loop from the C-terminal domain may contribute to interfacial binding.
Biochemistry 1998;37(34):11846-55.
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1998: Bezzine S; Roussel A; de Caro J; Gastinel L; de Caro A; Carrière F; Leydier S; Verger R; Cambillau C
An inactive pancreatic lipase-related protein is activated into a triglyceride-lipase by mutagenesis based on the 3-D structure.
Chemistry and physics of lipids 1998;93(1-2):103-14.
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1997: Carrière F; Rogalska E; Cudrey C; Ferrato F; Laugier R; Verger R
In vivo and in vitro studies on the stereoselective hydrolysis of tri- and diglycerides by gastric and pancreatic lipases.
Bioorganic & medicinal chemistry 1997;5(2):429-35.
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1997: Carrière F; Thirstrup K; Hjorth S; Ferrato F; Nielsen P F; Withers-Martinez C; Cambillau C; Boel E; Thim L; Verger R
Pancreatic lipase structure-function relationships by domain exchange.
Biochemistry 1997;36(1):239-48.
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1996: Withers-Martinez C; Carrière F; Verger R; Bourgeois D; Cambillau C
A pancreatic lipase with a phospholipase A1 activity: crystal structure of a chimeric pancreatic lipase-related protein 2 from guinea pig.
Structure (London, England : 1993) 1996;4(11):1363-74.
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1996: Verger R; Aoubalå M; Carrière F; Ransac S; Dupuis L; De Caro J; Ferrato F; Douchet I; Laugier R; De Caro A
Regulation of lumen fat digestion: enzymic aspects.
The Proceedings of the Nutrition Society 1996;55(1B):5-18.
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1995: Verger R; Ferrato F; Carrière F; Cudrey C; Rugani N; Gargouri Y; Hjorth A; Wöldike H; Boel E; Thim L
Relationships between structures and kinetic properties of pancreatic lipases.
Annals of the New York Academy of Sciences 1995;750():190-4.
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1995: Rugani N; Carrière F; Thim L; Borgstrom B; Sarda L
Lipid binding and activating properties of porcine pancreatic colipase split at the Ile79-Thr80 bond.
Biochimica et biophysica acta 1995;1247(2):185-94.
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1995: Thirstrup K; Carrière F; Hjorth S A; Rasmussen P B; Nielsen P F; Ladefoged C; Thim L; Boel E
Cloning and expression in insect cells of two pancreatic lipases and a procolipase from Myocastor coypus.
European journal of biochemistry / FEBS 1995;227(1-2):186-93.
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1995: Carrière F; Verger R; Lookene A; Olivecrona G
Lipase structures at the interface between chemistry and biochemistry.
EXS 1995;73():3-26.
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1994: Carrière F; Thirstrup K; Boel E; Verger R; Thim L
Structure-function relationships in naturally occurring mutants of pancreatic lipase.
Protein engineering 1994;7(4):563-9.
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1994: Thirstrup K; Verger R; Carrière F
Evidence for a pancreatic lipase subfamily with new kinetic properties.
Biochemistry 1994;33(10):2748-56.
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1994: Carrière F; Thirstrup K; Hjorth S; Boel E
Cloning of the classical guinea pig pancreatic lipase and comparison with the lipase related protein 2.
FEBS letters 1994;338(1):63-8.
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1993: Thirstrup K; Carrière F; Hjorth S; Rasmussen P B; Wöldike H; Nielsen P F; Thim L
One-step purification and characterization of human pancreatic lipase expressed in insect cells.
FEBS letters 1993;327(1):79-84.
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1993: Carrière F; Laugier R; Barrowman J A; Douchet I; Priymenko N; Verger R
Gastric and pancreatic lipase levels during a test meal in dogs.
Scandinavian journal of gastroenterology 1993;28(5):443-54.
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1993: Hjorth A; Carrière F; Cudrey C; Wöldike H; Boel E; Lawson D M; Ferrato F; Cambillau C; Dodson G G; Thim L
A structural domain (the lid) found in pancreatic lipases is absent in the guinea pig (phospho)lipase.
Biochemistry 1993;32(18):4702-7.
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1992: Moreau H; Abergel C; Carrière F; Ferrato F; Fontecilla-Camps J C; Cambillau C; Verger R
Isoform purification of gastric lipases. Towards crystallization.
Journal of molecular biology 1992;225(1):147-53.
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1992: Carrière F; Raphel V; Moreau H; Bernadac A; Devaux M A; Grimaud R; Barrowman J A; Bénicourt C; Junien J L; Laugier R
Dog gastric lipase: stimulation of its secretion in vivo and cytolocalization in mucous pit cells.
Gastroenterology 1992;102(5):1535-45.
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1991: Carrière F; Moreau H; Raphel V; Laugier R; Benicourt C; Junien J L; Verger R
Purification and biochemical characterization of dog gastric lipase.
European journal of biochemistry / FEBS 1991;202(1):75-83.
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