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Nils Færgeman

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Chemicals & Drugs

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Martin V Bennetzen; Nils Færgeman; Guido Kroemer; Guillermo Mariño; Eugenia Morselli; Dennis Pultz; Jens S Andersen
Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers.
Dennis Pultz; Steven Vestergaard Rødkær; Christine Zimmermann; Jens S Andersen; Martin V Bennetzen; Jorrit M Enserink; Nils Færgeman
Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.
Louise Cathrine Braun Olsen; Nils Færgeman
Chemical genomics and emerging DNA technologies in the identification of drug mechanisms and drug targets.

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2012: Martin V Bennetzen; Nils Færgeman; Guido Kroemer; Guillermo Mariño; Eugenia Morselli; Dennis Pultz; Jens S Andersen
Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers.
Cell cycle (Georgetown, Tex.) 2012;11(9):1827-40.
2012: Dennis Pultz; Steven Vestergaard Rødkær; Christine Zimmermann; Jens S Andersen; Martin V Bennetzen; Jorrit M Enserink; Nils Færgeman
Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae.
Molecular bioSystems 2012;8(3):796-803.
2012: Louise Cathrine Braun Olsen; Nils Færgeman
Chemical genomics and emerging DNA technologies in the identification of drug mechanisms and drug targets.
Current topics in medicinal chemistry 2012;12(12):1331-45.
2011: Ida C Elle; Pernille K Birck; Sidse Ehmsen; Thuc T Le; Louise C B Olsen; Karina T Simonsen; Simon Tuck; Nils Færgeman
Tissue- and paralogue-specific functions of acyl-CoA-binding proteins in lipid metabolism in Caenorhabditis elegans.
The Biochemical journal 2011;437(2):231-41.
2011: Julius Fredens; Anders Giessing; Peter Højrup; Martin Røssel Larsen; Jakob Møller-Jensen; Dennis Pultz; Kasper Engholm-Keller; Nils Færgeman
Quantitative proteomics by amino acid labeling in C. elegans.
Nature methods 2011;8(10):845-7.
2011: Emma Svensson; Christian Brackmann; Annika Enejder; Nils Færgeman; Catarina Mörck; Louise Olsen; Marc Pilon
The adiponectin receptor homologs in C. elegans promote energy utilization and homeostasis.
PloS one 2011;6(6):e21343.
2010: Brendan C Mullaney; Raymond D Blind; George A Lemieux; Carissa L Perez; Ida C Elle; Nils Færgeman; Marc R Van Gilst; Holly A Ingraham; Kaveh Ashrafi
Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25.
Cell metabolism 2010;12(4):398-410.
2010: Ida Coordt Elle; Louise Cathrine Braun Olsen; Dennis Pultz; Steven Vestergaard Rødkaer; Nils Færgeman
Something worth dyeing for: molecular tools for the dissection of lipid metabolism in Caenorhabditis elegans.
FEBS letters 2010;584(11):2183-93.
2010: Daniel Wüstner; Ane Landt Larsen; Nils Færgeman; Jonathan R Brewer; Daniel Sage
Selective visualization of fluorescent sterols in Caenorhabditis elegans by bleach-rate-based image segmentation.
Traffic (Copenhagen, Denmark) 2010;11(4):440-54.
2009: Catarina Mörck; Louise Olsen; Caroline Kurth; Annelie Persson; Nadia Jin Storm; Emma Svensson; John-Olov Jansson; Marika Hellqvist; Annika Enejder; Nils Færgeman; Marc Pilon
Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18285-90.
2009: Esther Marza; Karina T Simonsen; Nils Færgeman; Giovanni M Lesa
Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells.
Journal of cell science 2009;122(Pt 6):822-33.
2009: Kate Lykke Lambertsen; Bettina Hjelm Clausen; Alicia Babcock; Rikke Gregersen; Christina Fenger; Helle H Nielsen; Laila Skov Haugaard; Martin Wirenfeldt; Marianne Nielsen; Frederik Dagnaes-Hansen; Horst Bluethmann; Nils Færgeman; Michael Meldgaard; Tomas Deierborg; Bente Finsen
Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(5):1319-30.
2008: Daniel Wüstner; Nils Færgeman
Spatiotemporal analysis of endocytosis and membrane distribution of fluorescent sterols in living cells.
Histochemistry and cell biology 2008;130(5):891-908.
2008: Nicole Hartwig Petersen; Nils Færgeman; Nils J Faegeman; Liqing Yu; Daniel Wüstner
Kinetic imaging of NPC1L1 and sterol trafficking between plasma membrane and recycling endosomes in hepatoma cells.
Journal of lipid research 2008;49(9):2023-37.
2008: Daniel Wüstner; Nils Færgeman
Chromatic aberration correction and deconvolution for UV sensitive imaging of fluorescent sterols in cytoplasmic lipid droplets.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2008;73(8):727-44.
2008: Supriya Srinivasan; Leila Sadegh; Ida C Elle; Anne G L Christensen; Nils Færgeman; Kaveh Ashrafi
Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms.
Cell metabolism 2008;7(6):533-44.
2008: Jesper S Hansen; Nils Færgeman; Birthe Kragelund; Jens Knudsen
Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells.
The Biochemical journal 2008;410(3):463-72.
2007: Søren Feddersen; Thomas B F Neergaard; Jens Knudsen; Nils Færgeman
Transcriptional regulation of phospholipid biosynthesis is linked to fatty acid metabolism by an acyl-CoA-binding-protein-dependent mechanism in Saccharomyces cerevisiae.
The Biochemical journal 2007;407(2):219-30.
2007: Nils Færgeman; Majken Wadum; Søren Feddersen; Mark Burton; Birthe Kragelund; Jens Knudsen
Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA.
Molecular and cellular biochemistry 2007;299(1-2):55-65.
2007: Mikhail Y Golovko; Thad A Rosenberger; Søren Feddersen; Nils Færgeman; Eric Murphy
Alpha-synuclein gene ablation increases docosahexaenoic acid incorporation and turnover in brain phospholipids.
Journal of neurochemistry 2007;101(1):201-11.
2006: Morten K Larsen; Simon Tuck; Nils Færgeman; Jens Knudsen
MAA-1, a novel acyl-CoA-binding protein involved in endosomal vesicle transport in Caenorhabditis elegans.
Molecular biology of the cell 2006;17(10):4318-29.
2006: Jesper S Hansen; Jens K Villadsen; Michael Gaster; Nils Færgeman; Jens Knudsen
Micro method for determination of nonesterified fatty acid in whole blood obtained by fingertip puncture.
Analytical biochemistry 2006;355(1):29-38.
2006: Malene Just; Nils Færgeman; Jens Knudsen; Henning Beck-Nielsen; Michael Gaster
Long-chain Acyl-CoA is not primarily increased in myotubes established from type 2 diabetic subjects.
Biochimica et biophysica acta 2006;1762(7):666-72.
2006: Mikhail Y Golovko; Thad A Rosenberger; Nils Færgeman; Søren Feddersen; Nelson B Cole; Ingrid Pribill; Johannes Berger; Robert L Nussbaum; Eric Murphy
Acyl-CoA synthetase activity links wild-type but not mutant alpha-synuclein to brain arachidonate metabolism.
Biochemistry 2006;45(22):6956-66.
2005: Liping Hu; Jude T Deeney; Christopher J Nolan; Marie-Line Peyot; Ada Ao; Ann-Marie T Richard; Esthere Luc; Nils Færgeman; Jens Knudsen; Wen Guo; Maria Sorhede-Winzell; Marc Prentki; Barbara E Corkey
Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes.
American journal of physiology. Endocrinology and metabolism 2005;289(6):E1085-92.
2005: Mark Burton; Timothy M Rose; Nils Færgeman; Jens Knudsen
Evolution of the acyl-CoA binding protein (ACBP).
The Biochemical journal 2005;392(Pt 2):299-307.
2005: Mikhail Y Golovko; Nils Færgeman; Nelson B Cole; Paula I Castagnet; Robert L Nussbaum; Eric Murphy
Alpha-synuclein gene deletion decreases brain palmitate uptake and alters the palmitate metabolism in the absence of alpha-synuclein palmitate binding.
Biochemistry 2005;44(23):8251-9.
2005: Albrecht Gruhler; Jesper V Olsen; shabaz mohammed; Peter Mortensen; Nils Færgeman; Matthias Mann; Ole N Jensen
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Molecular & cellular proteomics : MCP 2005;4(3):310-27.
2004: Nils Færgeman; Søren Feddersen; Janne Klitgaard; Morten K Larsen; Roger Schneiter; Christian Ungermann; Kudzai E Mutenda; Peter Roepstorff; Jens Knudsen
Acyl-CoA-binding protein, Acb1p, is required for normal vacuole function and ceramide synthesis in Saccharomyces cerevisiae.
The Biochemical journal 2004;380(Pt 3):907-18.
2003: A Cohen Simonsen; U Bernchou Jensen; Nils Færgeman; Jens Knudsen; Ole G Mouritsen
Acyl-coenzyme A organizes laterally in membranes and is recognized specifically by acyl-coenzyme A binding protein.
FEBS letters 2003;552(2-3):253-8.
2003: Zhiying Zou; Fumin Tong; Nils Færgeman; Claus Børsting; Paul N Black; Concetta C DiRusso
Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex.
The Journal of biological chemistry 2003;278(18):16414-22.
2002: Nils Færgeman; Jens Knudsen
Acyl-CoA binding protein is an essential protein in mammalian cell lines.
The Biochemical journal 2002;368(Pt 3):679-82.
2002: Majken C T Wadum; Jens K Villadsen; Søren Feddersen; Rikke Steensbjerre Møller; Thomas B F Neergaard; Birthe Kragelund; Peter Højrup; Nils Færgeman; Jens Knudsen
Fluorescently labelled bovine acyl-CoA-binding protein acting as an acyl-CoA sensor: interaction with CoA and acyl-CoA esters and its use in measuring free acyl-CoA esters and non-esterified fatty acids.
The Biochemical journal 2002;365(Pt 1):165-72.
2001: Nils Færgeman; Paul N Black; X D Zhao; Jens Knudsen; Concetta C DiRusso
The Acyl-CoA synthetases encoded within FAA1 and FAA4 in Saccharomyces cerevisiae function as components of the fatty acid transport system linking import, activation, and intracellular Utilization.
The Journal of biological chemistry 2001;276(40):37051-9.
2001: Barbara Gaigg; Thomas B F Neergaard; Roger Schneiter; JK Hansen; Nils Færgeman; Niels A Jensen; Jens R Andersen; J Friis; Roger Sandhoff; H D Schrøder; Jens Knudsen
Depletion of acyl-coenzyme A-binding protein affects sphingolipid synthesis and causes vesicle accumulation and membrane defects in Saccharomyces cerevisiae.
Molecular biology of the cell 2001;12(4):1147-60.
2000: Concetta C DiRusso; E J Connell; Nils Færgeman; Jens Knudsen; JK Hansen; Paul N Black
Murine FATP alleviates growth and biochemical deficiencies of yeast fat1Delta strains.
European journal of biochemistry / FEBS 2000;267(14):4422-33.
2000: Paul N Black; Nils Færgeman; Concetta C DiRusso
Long-chain acyl-CoA-dependent regulation of gene expression in bacteria, yeast and mammals.
The Journal of nutrition 2000;130(2S Suppl):305S-309S.
2000: Nils Færgeman; T Ballegaard; Jens Knudsen; Paul N Black; Concetta C DiRusso
Possible roles of long-chain fatty Acyl-CoA esters in the fusion of biomembranes.
Sub-cellular biochemistry 2000;34():175-231.
1999: Jens Knudsen; Mette Jensen; JK Hansen; Nils Færgeman; Thomas B F Neergaard; Barbara Gaigg
Role of acylCoA binding protein in acylCoA transport, metabolism and cell signaling.
Molecular and cellular biochemistry 1999;192(1-2):95-103.
1997: Nils Færgeman; Jens Knudsen
Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling.
The Biochemical journal 1997;323 ( Pt 1)():1-12.
1997: Nils Færgeman; Concetta C DiRusso; Andrea J Elberger; Jens Knudsen; Paul N Black
Disruption of the Saccharomyces cerevisiae homologue to the murine fatty acid transport protein impairs uptake and growth on long-chain fatty acids.
The Journal of biological chemistry 1997;272(13):8531-8.
1996: Nils Færgeman; B W Sigurskjold; Birthe Kragelund; Kim Vilbour Andersen; Jens Knudsen
Thermodynamics of ligand binding to acyl-coenzyme A binding protein studied by titration calorimetry.
Biochemistry 1996;35(45):14118-26.
1995: Burkhard Rolf; E Oudenampsen-Krüger; Torsten Börchers; Nils Færgeman; Jens Knudsen; A Lezius; Friedrich Spener
Analysis of the ligand binding properties of recombinant bovine liver-type fatty acid binding protein.
Biochimica et biophysica acta 1995;1259(3):245-53.
1994: Jens Knudsen; Nils Færgeman; H Skøtt; R Hummel; C Børsting; Timothy M Rose; J S Andersen; Peter Højrup; Peter Roepstorff; Karsten Kristiansen
Yeast acyl-CoA-binding protein: acyl-CoA-binding affinity and effect on intracellular acyl-CoA pool size.
The Biochemical journal 1994;302 ( Pt 2)():479-85.
1994: J T Rasmussen; Nils Færgeman; Karsten Kristiansen; Jens Knudsen
Acyl-CoA-binding protein (ACBP) can mediate intermembrane acyl-CoA transport and donate acyl-CoA for beta-oxidation and glycerolipid synthesis.
The Biochemical journal 1994;299 ( Pt 1)():165-70.