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Leanne Cartee

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Leanne Cartee; Sonia C Maggio; Rebecca Smith; Heidi Sankala; Paul Dent; Steven Grant
Protein kinase C-dependent activation of the tumor necrosis factor receptor-mediated extrinsic cell death pathway underlies enhanced apoptosis in human myeloid leukemia cells exposed to bryostatin 1 and flavopiridol.
Leanne Cartee; Heidi Sankala; Christine Davis; Rebecca Smith; Sonia C Maggio; Peck-Sun Lin; Paul Dent; Steven Grant
7-hydroxystaurosporine (UCN-01) and ionizing radiation combine to inhibit the growth of Bcl-2-overexpressing U937 leukemia cells through a non-apoptotic mechanism.
Leanne Cartee; Rebecca Smith; Yun Dai; Mohamed Rahmani; Roberto R Rosato; Jorge A Almenara; Paul Dent; Steven Grant
Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways.

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2003: Leanne Cartee; Sonia C Maggio; Rebecca Smith; Heidi Sankala; Paul Dent; Steven Grant
Protein kinase C-dependent activation of the tumor necrosis factor receptor-mediated extrinsic cell death pathway underlies enhanced apoptosis in human myeloid leukemia cells exposed to bryostatin 1 and flavopiridol.
Molecular cancer therapeutics 2003;2(1):83-93.
2002: Leanne Cartee; Heidi Sankala; Christine Davis; Rebecca Smith; Sonia C Maggio; Peck-Sun Lin; Paul Dent; Steven Grant
7-hydroxystaurosporine (UCN-01) and ionizing radiation combine to inhibit the growth of Bcl-2-overexpressing U937 leukemia cells through a non-apoptotic mechanism.
International journal of oncology 2002;21(2):351-9.
2002: Leanne Cartee; Rebecca Smith; Yun Dai; Mohamed Rahmani; Roberto R Rosato; Jorge A Almenara; Paul Dent; Steven Grant
Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways.
Molecular pharmacology 2002;61(6):1313-21.
2002: Roberto R Rosato; Jorge A Almenara; Leanne Cartee; Vicki Betts; Srikumar Chellappan; Steven Grant
The cyclin-dependent kinase inhibitor flavopiridol disrupts sodium butyrate-induced p21WAF1/CIP1 expression and maturation while reciprocally potentiating apoptosis in human leukemia cells.
Molecular cancer therapeutics 2002;1(4):253-66.
2001: Leanne Cartee; Zhiliang Wang; Roy H Decker; Srikumar Chellappan; Gina Fusaro; K G Hirsch; Heidi Sankala; Paul Dent; Steven Grant
The cyclin-dependent kinase inhibitor (CDKI) flavopiridol disrupts phorbol 12-myristate 13-acetate-induced differentiation and CDKI expression while enhancing apoptosis in human myeloid leukemia cells.
Cancer research 2001;61(6):2583-91.
2000: Leanne Cartee; C Davis; Peck-Sun Lin; Steven Grant
Chronic exposure to bryostatin-1 increases the radiosensitivity of U937 leukaemia cells ectopically expressing Bcl-2 through a non-apoptotic mechanism.
International journal of radiation biology 2000;76(10):1323-33.
2000: Leanne Cartee; Julie Vrana; Zhiliang Wang; Jong Sung Park; Michael J Birrer; Paul B Fisher; Steven Grant; Paul Dent
Inhibition of the mitogen activated protein kinase pathway potentiates radiation-induced cell killing via cell cycle arrest at the G2/M transition and independently of increased signaling by the JNK/c-Jun pathway.
International journal of oncology 2000;16(2):413-22.