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David Lanar

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Stephen A Kaba; Clara Brando; Peter Burkhard; Andrea Crisanti; Debleena Dasgupta; Tais A P F Doll; Qin Guo; Margaret E McCoy; Christian Mittelholzer; Roberta Spaccapelo; Yongkun Yang; David Lanar
Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine.
James F Cummings; Michele D Spring; Robert Schwenk; Christian F Ockenhouse; Kent Kester; Mark E Polhemus; Douglas S Walsh; In-Kyu Yoon; Christine Prosperi; Laure Y Juompan; David Lanar; Urszula Krzych; B Ted Hall; Lisa A Ware; V Ann Stewart; Jack Williams; Megan G Dowler; Robin K Nielsen; Collette J Hillier; Birgitte K Giersing; Filip Dubovsky; Elissa Malkin; Kathryn Tucker; Marie-Claude Dubois; Joe D Cohen; W Ripley Ballou; Donald Heppner
Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-gamma/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection.
Amolo S Asito; Erwan Piriou; Peter Sumba Odada; Nancy Fiore; Jaap Middeldorp; Carole A Long; Sheetij Dutta; David Lanar; Walter G Jura; Collins Ouma; Juliana A Otieno; Ann M Moormann; Rosemary Rochford
Elevated anti-Zta IgG levels and EBV viral load are associated with site of tumor presentation in endemic Burkitt's lymphoma patients: a case control study.

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All Publications

2012: Stephen A Kaba; Clara Brando; Peter Burkhard; Andrea Crisanti; Debleena Dasgupta; Tais A P F Doll; Qin Guo; Margaret E McCoy; Christian Mittelholzer; Roberta Spaccapelo; Yongkun Yang; David Lanar
Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine.
PloS one 2012;7(10):e48304.
2010: James F Cummings; Michele D Spring; Robert Schwenk; Christian F Ockenhouse; Kent Kester; Mark E Polhemus; Douglas S Walsh; In-Kyu Yoon; Christine Prosperi; Laure Y Juompan; David Lanar; Urszula Krzych; B Ted Hall; Lisa A Ware; V Ann Stewart; Jack Williams; Megan G Dowler; Robin K Nielsen; Collette J Hillier; Birgitte K Giersing; Filip Dubovsky; Elissa Malkin; Kathryn Tucker; Marie-Claude Dubois; Joe D Cohen; W Ripley Ballou; Donald Heppner
Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-gamma/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection.
Vaccine 2010;28(31):5135-44.
2010: Amolo S Asito; Erwan Piriou; Peter Sumba Odada; Nancy Fiore; Jaap Middeldorp; Carole A Long; Sheetij Dutta; David Lanar; Walter G Jura; Collins Ouma; Juliana A Otieno; Ann M Moormann; Rosemary Rochford
Elevated anti-Zta IgG levels and EBV viral load are associated with site of tumor presentation in endemic Burkitt's lymphoma patients: a case control study.
Infectious agents and cancer 2010;5():13.
2010: Mahamadou A Thera; Ogobara K Doumbo; Drissa Coulibaly; Matthew Laurens; Abdoulaye K Kone; Ando B Guindo; Karim Traore; Mady Sissoko; Dapa A Diallo; Issa Diarra; Bourema Kouriba; Modibo Daou; Amagana Dolo; Mounirou Baby; Mahamadou S Sissoko; Issaka Sagara; Amadou Niangaly; Idrissa Traore; Ally Olotu; Olivier Godeaux; Amanda Leach; Marie-Claude Dubois; W Ripley Ballou; Joe Cohen; Darby Thompson; Tina Dube; Lorraine Soisson; Carter L Diggs; Shannon Takala Harrison; Kirsten E Lyke; Brent House; David Lanar; Sheetij Dutta; DONALD HEPPNER; Christopher Plowe
Safety and immunogenicity of an AMA1 malaria vaccine in Malian children: results of a phase 1 randomized controlled trial.
PloS one 2010;5(2):e9041.
2009: Sathit Pichyangkul; Pongsri Tongtawe; Utaiwan Kum-arb; Kosol Yongvanitchit; Montip Gettayacamin; M R Hollingdale; A Limsalakpetch; V Ann Stewart; David Lanar; S Dutta; Evelina Angov; L A Ware; Elke Bergmann-Leitner; B House; Gerald Voss; M C Dubois; Joe D Cohen; M M Fukuda; Donald Heppner; R Scott Miller
Evaluation of the safety and immunogenicity of Plasmodium falciparum apical membrane antigen 1, merozoite surface protein 1 or RTS,S vaccines with adjuvant system AS02A administered alone or concurrently in rhesus monkeys.
Vaccine 2009;28(2):452-62.
2009: Stephen A Kaba; Clara Brando; Qin Guo; Christian Mittelholzer; Senthilkumar Raman; David Tropel; Ueli Aebi; Peter Burkhard; David Lanar
A nonadjuvanted polypeptide nanoparticle vaccine confers long-lasting protection against rodent malaria.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(11):7268-77.
2009: Kirsten E Lyke; Modibo Daou; Issa Diarra; Abdoulaye Kone; Bourema Kouriba; Mahamadou A Thera; Sheetij Dutta; David Lanar; Donald Heppner; Ogobara K Doumbo; Christopher Plowe; Marcelo B Sztein
Cell-mediated immunity elicited by the blood stage malaria vaccine apical membrane antigen 1 in Malian adults: results of a Phase I randomized trial.
Vaccine 2009;27(15):2171-6.
2009: Sheetij Dutta; JoAnn S Sullivan; Katharine K Grady; J David Haynes; Jack Komisar; Adrian H Batchelor; Lorraine Soisson; Carter L Diggs; Donald Heppner; David Lanar; William E Collins; John W Barnwell
High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model.
PloS one 2009;4(12):e8138.
2009: Michele D Spring; James F Cummings; Christian F Ockenhouse; Sheetij Dutta; Randall Reidler; Evelina Angov; Elke Bergmann-Leitner; V Ann Stewart; Stacey Bittner; Laure Juompan; Mark G Kortepeter; Robin Nielsen; Urszula Krzych; Ev Tierney; Lisa A Ware; Megan Dowler; Cornelus C Hermsen; Robert W Sauerwein; Sake J de Vlas; Opokua Ofori-Anyinam; David Lanar; Jack L Williams; Kent E Kester; Kathryn Tucker; Meng Shi; Elissa Malkin; Carole A Long; Carter L Diggs; Lorraine Soisson; Marie-Claude Dubois; W Ripley Ballou; Joe Cohen; DONALD HEPPNER
Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.
PloS one 2009;4(4):e5254.
2008: Renée M Ned; April E Price; Sara B Crawford; John G Ayisi; Anna M van Eijk; Juliana A Otieno; Bernard L Nahlen; Richard W Steketee; Laurence Slutsker; Ya Ping Shi; David Lanar; Venkatachalam Udhayakumar
Effect of placental malaria and HIV infection on the antibody responses to Plasmodium falciparum in infants.
The Journal of infectious diseases 2008;198(11):1609-19.
2008: Gregory S Noland; Brett Hendel-Paterson; Xinan M Min; Ann M Moormann; John M Vulule; David Narum; David Lanar; James W Kazura; Chandy C John
Low prevalence of antibodies to preerythrocytic but not blood-stage Plasmodium falciparum antigens in an area of unstable malaria transmission compared to prevalence in an area of stable malaria transmission.
Infection and immunity 2008;76(12):5721-8.
2008: F H A Osier; Greg Fegan; Spencer D Polley; Linda Murungi; Federica Verra; Kevin K A Tetteh; Brett Lowe; Tabitha Mwangi; Peter C Bull; Alan Thomas; David Cavanagh; Jana S McBride; David Lanar; Margaret J Mackinnon; David J Conway; Kevin Marsh
Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria.
Infection and immunity 2008;76(5):2240-8.
2008: Onome J Akpogheneta; Nancy O Duah; Kevin K A Tetteh; Sam Dunyo; David Lanar; Margaret Pinder; David J Conway
Duration of naturally acquired antibody responses to blood-stage Plasmodium falciparum is age dependent and antigen specific.
Infection and immunity 2008;76(4):1748-55.
2008: Ariane Rodríguez; Jaap Goudsmit; Arjen Companjen; Ratna Mintardjo; Gert Gillissen; Dennis Tax; Jeroen Sijtsma; Gerrit Jan Weverling; Lennart Holterman; David Lanar; Menzo J E Havenga; Katarina Radosevic
Impact of recombinant adenovirus serotype 35 priming versus boosting of a Plasmodium falciparum protein: characterization of T- and B-cell responses to liver-stage antigen 1.
Infection and immunity 2008;76(4):1709-18.
2008: Chandy C John; Aaron J Tande; Ann M Moormann; Peter O Sumba; David Lanar; Xinan M Min; James W Kazura
Antibodies to pre-erythrocytic Plasmodium falciparum antigens and risk of clinical malaria in Kenyan children.
The Journal of infectious diseases 2008;197(4):519-26.
2008: Panita Gosi; Srisin Khusmith; Thareerat Khalambaheti; David Lanar; Kurt E Schaecher; Mark M Fukuda; Scott R Miller
Polymorphism patterns in Duffy-binding protein among Thai Plasmodium vivax isolates.
Malaria journal 2008;7():112.
2008: Mahamadou A Thera; Ogobara K Doumbo; Drissa Coulibaly; Dapa A Diallo; Abdoulaye K Kone; Ando B Guindo; Karim Traore; Alassane Dicko; Issaka Sagara; Mahamadou S Sissoko; Mounirou Baby; Mady Sissoko; Issa Diarra; Amadou Niangaly; Amagana Dolo; Modibo Daou; Sory I Diawara; DONALD HEPPNER; V Ann Stewart; Evelina Angov; Elke Bergmann-Leitner; David Lanar; Sheetij Dutta; Lorraine Soisson; Carter L Diggs; Amanda Leach; Alex Owusu; Marie-Claude Dubois; Joe Cohen; Jason N Nixon; Aric Gregson; Shannon Takala Harrison; Kirsten E Lyke; Christopher Plowe
Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial.
PloS one 2008;3(1):e1465.
2008: Sathit Pichyangkul; Utaiwan Kum-arb; Kosol Yongvanitchit; A Limsalakpetch; Montip Gettayacamin; David Lanar; Lisa A Ware; V Ann Stewart; Donald Heppner; Pascal Mettens; Joe D Cohen; W Ripley Ballou; M M Fukuda
Preclinical evaluation of the safety and immunogenicity of a vaccine consisting of Plasmodium falciparum liver-stage antigen 1 with adjuvant AS01B administered alone or concurrently with the RTS,S/AS01B vaccine in rhesus primates.
Infection and immunity 2008;76(1):229-38.
2007: Deep C Kaushal; Nuzhat A Kaushal; Atul Narula; Niraj Kumar; SUNIL KUMAR PURI; Shitij Dutta; David Lanar
Biochemical and immunological characterization of E. coli expressed 42 kDa fragment of Plasmodium vivax and P. cynomolgi bastianelli merozoite surface protein-1.
Indian journal of biochemistry & biophysics 2007;44(6):429-36.
2007: Sheetij Dutta; Seung Yeon Lee; Adrian H Batchelor; David Lanar
Structural basis of antigenic escape of a malaria vaccine candidate.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12488-93.
2007: Mark E Polhemus; Alan J Magill; James F Cummings; Kent Kester; Christian F Ockenhouse; David Lanar; Sheetij Dutta; Arnoldo Barbosa; Lorraine Soisson; Carter L Diggs; Sally A Robinson; J David Haynes; V Ann Stewart; Lisa A Ware; Clara Brando; Urszula Krzych; Robert A Bowden; Joe D Cohen; Marie-Claude Dubois; Opokua Ofori-Anyinam; Els De-Kock; W Ripley Ballou; Donald Heppner
Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naïve adults at the Walter Reed Army Institute of Research.
Vaccine 2007;25(21):4203-12.
2007: Clara Brando; Lisa A Ware; Helen Freyberger; April Kathcart; Arnoldo Barbosa; Sylvie Cayphas; Marie-Ange Demoitie; Pascal Mettens; Donald Heppner; David Lanar
Murine immune responses to liver-stage antigen 1 protein FMP011, a malaria vaccine candidate, delivered with adjuvant AS01B or AS02A.
Infection and immunity 2007;75(2):838-45.
2007: George Jiang; Yupin Charoenvit; Alberto Moreno; Maria F Baraceros; Glenna Banania; Nancy Richie; Steve Abot; Harini Ganeshan; Victoria Fallarme; Noelle B Patterson; Andrew Geall; Walter R Weiss; Elizabeth Strobert; Ivette Caro-Aquilar; David Lanar; Allan Saul; Laura B Martin; Kalpana Gowda; Craig R Morrissette; David C Kaslow; Daniel J Carucci; Mary R Galinski; Denise L Doolan
Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization.
Malaria journal 2007;6():135.
2007: Samson Kinyanjui; David J Conway; David Lanar; Kevin Marsh
IgG antibody responses to Plasmodium falciparum merozoite antigens in Kenyan children have a short half-life.
Malaria journal 2007;6():82.
2006: Godfree Mlambo; Susan L Mutambu; Takafira MDULUZA; White Soko; Joel Mbedzi; James Chivenga; David Lanar; Sanjay Singh; Daniel J Carucci; Armin Gemperli; Nirbhay Kumar
Antibody responses to Plasmodium falciparum vaccine candidate antigens in three areas distinct with respect to altitude.
Acta tropica 2006;100(1-2):70-8.
2006: Peter K Chiang; Janusz Bujnicki; Xinzhuan Su; David Lanar
Malaria: therapy, genes and vaccines.
Current molecular medicine 2006;6(3):309-26.
2005: Sheetij Dutta; Deep C Kaushal; Lisa A Ware; SUNIL KUMAR PURI; Nuzhat A Kaushal; Atul Narula; D S Upadhyaya; David Lanar
Merozoite surface protein 1 of Plasmodium vivax induces a protective response against Plasmodium cynomolgi challenge in rhesus monkeys.
Infection and immunity 2005;73(9):5936-44.
2005: Kiprotich Chelimo; Ayub V Ofulla; David Narum; James W Kazura; David Lanar; Chandy C John
Antibodies to Plasmodium falciparum antigens vary by age and antigen in children in a malaria-holoendemic area of Kenya.
The Pediatric infectious disease journal 2005;24(8):680-4.
2005: Chandy C John; Ann M Moormann; Daniel C Pregibon; Peter O Sumba; Marilyn M McHugh; David Narum; David Lanar; Mark Schluchter; James W Kazura
Correlation of high levels of antibodies to multiple pre-erythrocytic Plasmodium falciparum antigens and protection from infection.
The American journal of tropical medicine and hygiene 2005;73(1):222-8.
2005: Sheetij Dutta; J David Haynes; Arnoldo Barbosa; Lisa A Ware; Jeffrey D Snavely; J Kathleen Moch; Alan Thomas; David Lanar
Mode of action of invasion-inhibitory antibodies directed against apical membrane antigen 1 of Plasmodium falciparum.
Infection and immunity 2005;73(4):2116-22.
2005: Collette J Hillier; Lisa A Ware; Arnoldo Barbosa; Evelina Angov; Jeffrey A Lyon; Donald Heppner; David Lanar
Process development and analysis of liver-stage antigen 1, a preerythrocyte-stage protein-based vaccine for Plasmodium falciparum.
Infection and immunity 2005;73(4):2109-15.
2005: DONALD HEPPNER; Kent E Kester; Christian F Ockenhouse; Nadia Tornieporth; Opokua Ofori; Jeffrey A Lyon; V Ann Stewart; Patrice Dubois; David Lanar; Urszula Krzych; Philippe Moris; Evelina Angov; James F Cummings; Amanda Leach; B Ted Hall; Sheetij Dutta; Robert Schwenk; Collette Hillier; Arnoldo Barbosa; Lisa A Ware; Lalitha Nair; Christian A Darko; Mark R Withers; Bernhards Ogutu; Mark E Polhemus; Mark Fukuda; Sathit Pichyangkul; Montip Gettyacamin; Carter Diggs; Lorraine Soisson; Jessica Milman; Marie-Claude Dubois; Nathalie Garçon; Kathryn Tucker; Janet Wittes; Christopher Plowe; Mahamadou A Thera; Ogobara K Duombo; Maria G Pau; Jaap Goudsmit; W Ripley Ballou; Joe Cohen
Towards an RTS,S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research.
Vaccine 2005;23(17-18):2243-50.
2004: Spencer D Polley; Tabitha W Mwangi; Clemens H M Kocken; Alan Thomas; Sheetij Dutta; David Lanar; Edmond J Remarque; Amanda Ross; Thomas N Williams; Gabrielle Mwambingu; Brett Lowe; David J Conway; Kevin Marsh
Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malaria.
Vaccine 2004;23(5):718-28.
2004: Martha Sedegah; Yupin Charoenvit; Joao C Aguiar; John B Sacci; Richard C Hedstrom; Sanjai Kumar; Arnel Belmonte; David Lanar; Trevor R Jones; Esteban Abot; Pierre Druilhe; G Corradin; Judith E Epstein; Thomas L Richie; Daniel J Carucci; Stephen L Hoffman
Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF.
Genes and immunity 2004;5(7):553-61.
2004: W Ripley Ballou; Myriam Arevalo-Herrera; Daniel J Carucci; Thomas L Richie; Giampietro Corradin; Carter L Diggs; Pierre Druilhe; Birgitte K Giersing; Allan Saul; Donald Heppner; Kent Kester; David Lanar; Jeff Lyon; Adrian V S Hill; Weiqing Pan; Joe D Cohen
Update on the clinical development of candidate malaria vaccines.
The American journal of tropical medicine and hygiene 2004;71(2 Suppl):239-47.
2004: P V Lalitha; Lisa A Ware; Arnoldo Barbosa; Sheetij Dutta; J Kathleen Moch; J David Haynes; Bader B Fileta; Charles E White; David Lanar
Production of the subdomains of the Plasmodium falciparum apical membrane antigen 1 ectodomain and analysis of the immune response.
Infection and immunity 2004;72(8):4464-70.
2004: Eunita A Ohas; John H Adams; John N Waitumbi; Alloys S S Orago; Arnoldo Barbosa; David Lanar; Jose Stoute
Measurement of antibody levels against region II of the erythrocyte-binding antigen 175 of Plasmodium falciparum in an area of malaria holoendemicity in western Kenya.
Infection and immunity 2004;72(2):735-41.
2003: Sheetij Dutta; J David Haynes; J Kathleen Moch; Arnoldo Barbosa; David Lanar
Invasion-inhibitory antibodies inhibit proteolytic processing of apical membrane antigen 1 of Plasmodium falciparum merozoites.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12295-300.
2003: Jennifer F Friedman; Jonathan D Kurtis; Ramadhan Mtalib; Malachi Opollo; David Lanar; Patrick Duffy
Malaria is related to decreased nutritional status among male adolescents and adults in the setting of intense perennial transmission.
The Journal of infectious diseases 2003;188(3):449-57.
2003: Lauren M Singer; Lisa B Mirel; Feiko O ter Kuile; OraLee Branch; John M Vulule; Margarette S Kolczak; William A Hawley; Simon K Kariuki; David C Kaslow; David Lanar; Altaf A Lal
The effects of varying exposure to malaria transmission on development of antimalarial antibody responses in preschool children. XVI. Asembo Bay Cohort Project.
The Journal of infectious diseases 2003;187(11):1756-64.
2003: John G Ayisi; OraLee Branch; A Rafi-Janajreh; Anna M van Eijk; Feiko O ter Kuile; Daniel H Rosen; Piet A Kager; David Lanar; Arnoldo Barbosa; David C Kaslow; Bernard L Nahlen; Altaf A Lal
Does infection with Human Immunodeficiency Virus affect the antibody responses to Plasmodium falciparum antigenic determinants in asymptomatic pregnant women?
The Journal of infection 2003;46(3):164-72.
2003: Robert Schwenk; Ludmila V Asher; Isaac Chalom; David Lanar; Peifang Sun; Katherine White; Deborah Keil; Kent Kester; Jose Stoute; Donald Heppner; Urszula Krzych
Opsonization by antigen-specific antibodies as a mechanism of protective immunity induced by Plasmodium falciparum circumsporozoite protein-based vaccine.
Parasite immunology 2003;25(1):17-25.
2002: Sheetij Dutta; P V Lalitha; Lisa A Ware; Arnoldo Barbosa; J Kathleen Moch; Meredith A Vassell; Bader B Fileta; Svetlana Kitov; Nelly Kolodny; Donald Heppner; J David Haynes; David Lanar
Purification, characterization, and immunogenicity of the refolded ectodomain of the Plasmodium falciparum apical membrane antigen 1 expressed in Escherichia coli.
Infection and immunity 2002;70(6):3101-10.
2001: Dharmendar Rathore; Sanjai Kumar; David Lanar; Thomas F McCutchan
Disruption of disulfide linkages of the Plasmodium falciparum circumsporozoite protein: effects on cytotoxic and antibody responses in mice.
Molecular and biochemical parasitology 2001;118(1):75-82.
2001: Joao C Aguiar; Richard C Hedstrom; William O Rogers; Yupin Charoenvit; John B Sacci; David Lanar; Victoria Majam; R R Stout; Stephen L Hoffman
Enhancement of the immune response in rabbits to a malaria DNA vaccine by immunization with a needle-free jet device.
Vaccine 2001;20(1-2):275-80.
2001: Nelly Kolodny; Svetlana Kitov; M A Vassell; V L Miller; Lisa A Ware; Konstantin Fegeding; Patricia de la Vega; John B Sacci; David Lanar
Two-step chromatographic purification of recombinant Plasmodium falciparum circumsporozoite protein from Escherichia coli.
Journal of chromatography. B, Biomedical sciences and applications 2001;762(1):77-86.
2001: Sheetij Dutta; Lisa A Ware; Arnoldo Barbosa; Christian F Ockenhouse; David Lanar
Purification, characterization, and immunogenicity of a disulfide cross-linked Plasmodium vivax vaccine candidate antigen, merozoite surface protein 1, expressed in Escherichia coli.
Infection and immunity 2001;69(9):5464-70.
2001: Jonathan D Kurtis; Michael R Hollingdale; Adrian J F Luty; David Lanar; Urszula Krzych; Patrick Duffy
Pre-erythrocytic immunity to Plasmodium falciparum: the case for an LSA-1 vaccine.
Trends in parasitology 2001;17(5):219-23.
2001: Christian F Ockenhouse; Arnoldo Barbosa; D P Blackall; CI Murphy; Oscar Kashala; Sheetij Dutta; David Lanar; JR Daugherty
Sialic acid-dependent binding of baculovirus-expressed recombinant antigens from Plasmodium falciparum EBA-175 to Glycophorin A.
Molecular and biochemical parasitology 2001;113(1):9-21.
2000: Daniel M N Okenu; Eleanor M Riley; Quentin Bickle; P U Agomo; Arnoldo Barbosa; JR Daugherty; David Lanar; David J Conway
Analysis of human antibodies to erythrocyte binding antigen 175 of Plasmodium falciparum.
Infection and immunity 2000;68(10):5559-66.
2000: Sheetij Dutta; JR Daugherty; Lisa A Ware; David Lanar; Christian F Ockenhouse
Expression, purification and characterization of a functional region of the Plasmodium vivax Duffy binding protein.
Molecular and biochemical parasitology 2000;109(2):179-84.
1999: Peter K Chiang; ME Chamberlin; D Nicholson; SC Soubes; Xinzhuan Su; G. SUBRAMANIAN; David Lanar; Sean T Prigge; J P Scovill; Louis H Miller; Janice Yang Chou
Molecular characterization of Plasmodium falciparum S-adenosylmethionine synthetase.
The Biochemical journal 1999;344 Pt 2():571-6.
1999: Jonathan D Kurtis; David Lanar; M Opollo; Patrick Duffy
Interleukin-10 responses to liver-stage antigen 1 predict human resistance to Plasmodium falciparum.
Infection and immunity 1999;67(7):3424-9.
1998: Jose Stoute; Kent Kester; Urszula Krzych; Bruce T Wellde; Ted Hall; Katherine White; G Glenn; Christian F Ockenhouse; N Garcon; Robert Schwenk; David Lanar; Peifang Sun; P Momin; Robert A Wirtz; CF Golenda; Moncef Slaoui; Glenn Wortmann; Carolyn Holland; Megan G Dowler; Joe Cohen; W Ripley Ballou
Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine.
The Journal of infectious diseases 1998;178(4):1139-44.
1998: Christian F Ockenhouse; P F Sun; David Lanar; Bruce T Wellde; B T Hall; Kent Kester; Jose Stoute; Alan J Magill; Urszula Krzych; L Farley; Robert A Wirtz; J C Sadoff; David C Kaslow; Sanjai Kumar; L.W. Preston Church; J M Crutcher; Benjamin Wizel; S Hoffman; Ajit Lalvani; A V Hill; John A Tine; K P Guito; C de Taisne; R Anders; W Ripley Ballou
Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria.
The Journal of infectious diseases 1998;177(6):1664-73.
1997: JR Daugherty; CI Murphy; LA Doros-Richert; Arnoldo Barbosa; L O Kashala; W Ripley Ballou; N J Snellings; Christian F Ockenhouse; David Lanar
Baculovirus-mediated expression of Plasmodium falciparum erythrocyte binding antigen 175 polypeptides and their recognition by human antibodies.
Infection and immunity 1997;65(9):3631-7.
1996: John A Tine; David Lanar; D M Smith; Bruce T Wellde; P Schultheiss; L A Ware; E B Kauffman; Robert A Wirtz; C De Taisne; G S Hui; S P Chang; P Church; M R Hollingdale; David C Kaslow; S Hoffman; K P Guito; W Ripley Ballou; J C Sadoff; E Paoletti
NYVAC-Pf7: a poxvirus-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria.
Infection and immunity 1996;64(9):3833-44.
1996: David Lanar; John A Tine; C de Taisne; M C Seguin; W I Cox; J P Winslow; L A Ware; E B Kauffman; D Gordon; W Ripley Ballou; E Paoletti; J C Sadoff
Attenuated vaccinia virus-circumsporozoite protein recombinants confer protection against rodent malaria.
Infection and immunity 1996;64(5):1666-71.
1996: David Lanar; Kevin Kain; Henry B Burch
Epitope mapping of protein antigens by expression-PCR (E-PCR).
Methods in molecular biology (Clifton, N.J.) 1996;66():309-17.
1995: Benjamin Wizel; R Houghten; P Church; John A Tine; David Lanar; D M Gordon; W Ripley Ballou; Alessandro Sette; Stephen L Hoffman
HLA-A2-restricted cytotoxic T lymphocyte responses to multiple Plasmodium falciparum sporozoite surface protein 2 epitopes in sporozoite-immunized volunteers.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):766-75.
1994: David Lanar; Kevin Kain
Expression-PCR (E-PCR): overview and applications.
PCR methods and applications 1994;4(2):S92-6.
1994: Benjamin Wizel; William O Rogers; R A Houghten; David Lanar; John A Tine; Stephen L Hoffman
Induction of murine cytotoxic T lymphocytes against Plasmodium falciparum sporozoite surface protein 2.
European journal of immunology 1994;24(7):1487-95.
1993: Kevin Kain; P A Orlandi; J D Haynes; K L Sim; David Lanar
Evidence for two-stage binding by the 175-kD erythrocyte binding antigen of Plasmodium falciparum.
The Journal of experimental medicine 1993;178(5):1497-505.
1993: Kevin Kain; A E Brown; David Lanar; W Ripley Ballou; Horace Webster
Response of Plasmodium vivax variants to chloroquine as determined by microscopy and quantitative polymerase chain reaction.
The American journal of tropical medicine and hygiene 1993;49(4):478-84.
1993: L A Ware; Kevin Kain; B K Lee Sim; J D Haynes; J K Baird; David Lanar
Two alleles of the 175-kilodalton Plasmodium falciparum erythrocyte binding antigen.
Molecular and biochemical parasitology 1993;60(1):105-9.
1993: Henry B Burch; E V Nagy; Kevin Kain; David Lanar; F E Carr; L Wartofsky; Kenneth D Burman
Expression polymerase chain reaction for the in vitro synthesis and epitope mapping of autoantigen. Application to the human thyrotropin receptor.
Journal of immunological methods 1993;158(1):123-30.
1992: Kevin Kain; A E Brown; Horace Webster; Robert A Wirtz; J S Keystone; Mario Rodriguez; J Kinahan; M Rowland; David Lanar
Circumsporozoite genotyping of global isolates of Plasmodium vivax from dried blood specimens.
Journal of clinical microbiology 1992;30(7):1863-6.
1992: Kevin Kain; Robert A Wirtz; I Fernandez; E D Franke; Mario Rodriguez; David Lanar
Serologic and genetic characterization of Plasmodium vivax from whole blood-impregnated filter paper discs.
The American journal of tropical medicine and hygiene 1992;46(4):473-9.
1991: Kevin Kain; J Keystone; E D Franke; David Lanar
Global distribution of a variant of the circumsporozoite gene of Plasmodium vivax.
The Journal of infectious diseases 1991;164(1):208-10.
1991: Kevin Kain; David Lanar
Determination of genetic variation within Plasmodium falciparum by using enzymatically amplified DNA from filter paper disks impregnated with whole blood.
Journal of clinical microbiology 1991;29(6):1171-4.
1991: Kevin Kain; P A Orlandi; David Lanar
Universal promoter for gene expression without cloning: expression-PCR.
BioTechniques 1991;10(3):366-74.
1990: David Lanar
Sequence of the circumsporozoite gene of Plasmodium berghei ANKA clone and NK65 strain.
Molecular and biochemical parasitology 1990;39(1):151-3.
1990: Urszula Krzych; K White; H T Link; J Sadoff; David Lanar; W Ripley Ballou; T Jareed; A Agarwal
Role of circumsporozoite protein-specific T-cells in protective immunity against Plasmodium berghei.
Bulletin of the World Health Organization 1990;68 Suppl():88-93.
1989: Ronald Rosenberg; Robert A Wirtz; David Lanar; jetsumon prachumsri; T Hall; Andrew P Waters; C Prasittisuk
Circumsporozoite protein heterogeneity in the human malaria parasite Plasmodium vivax.
Science (New York, N.Y.) 1989;245(4921):973-6.
1989: David Lanar; Gerald McLaughlin; D F Wirth; R J Barker; J W Zolg; J D Chulay
Comparison of thick films, in vitro culture and DNA hybridization probes for detecting Plasmodium falciparum malaria.
The American journal of tropical medicine and hygiene 1989;40(1):3-6.
1988: E J Pearce; S L James; Sara Hieny; David Lanar; A Sher
Induction of protective immunity against Schistosoma mansoni by vaccination with schistosome paramyosin (Sm97), a nonsurface parasite antigen.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5678-82.
1987: C Cohen; David Lanar; D A Parry
Amino acid sequence and structural repeats in schistosome paramyosin match those of myosin.
Bioscience reports 1987;7(1):11-6.
1986: David Lanar; E J Pearce; S L James; A Sher
Identification of paramyosin as schistosome antigen recognized by intradermally vaccinated mice.
Science (New York, N.Y.) 1986;234(4776):593-6.
1985: David Lanar; E J Pearce; A Sher
Expression in Escherichia coli of two Schistosoma mansoni genes that encode major antigens recognized by immune mice.
Molecular and biochemical parasitology 1985;17(1):45-60.
1984: David Lanar; Jerry E Manning
Major surface proteins and antigens on the different in vivo and in vitro forms of Trypanosoma cruzi.
Molecular and biochemical parasitology 1984;11():119-31.
1981: David Lanar; Laura S Levy; Jerry E Manning
Complexity and content of the DNA and RNA in Trypanosoma cruzi.
Molecular and biochemical parasitology 1981;3(5):327-41.
1979: David Lanar
Growth and differentiation of Trypanosoma cruzi cultivated with a Triatoma infestans embryo cell line.
The Journal of protozoology 1979;26(3):457-62.