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Carmen Gil

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Chemicals & Drugs

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Publications

TOP 3
J A Morales-García; V Palomo; C Pérez; D I Pérez; S Alonso-Gil; S Conde; Carmen Gil; A Martínez; Angel Santos; C Susín; A Pérez-Castillo
Glycogen synthase kinase-3 inhibitors as potent therapeutic agents for the treatment of Parkinson disease.
Cecilia Chavarría; Carmen Gil; Jose A Morales Garcia; Concepción Pérez; Daniel I Perez; Ana Pérez-Castillo; Sandra Alonso-Gil; José M Souza; Williams Porcal
Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress.
Jose A Morales-Garcia; Valle Palomo; Angel Santos; Marina Sanz-Sancristobal; Sandra Alonso-Gil; Carmen Gil; Rosario Luna-Medina; Ana Martinez; Ana Perez-Castillo
Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo.

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All Publications

2013: J A Morales-García; V Palomo; C Pérez; D I Pérez; S Alonso-Gil; S Conde; Carmen Gil; A Martínez; Angel Santos; C Susín; A Pérez-Castillo
Glycogen synthase kinase-3 inhibitors as potent therapeutic agents for the treatment of Parkinson disease.
ACS chemical neuroscience 2013;4(2):350-60.
2012: Cecilia Chavarría; Carmen Gil; Jose A Morales Garcia; Concepción Pérez; Daniel I Perez; Ana Pérez-Castillo; Sandra Alonso-Gil; José M Souza; Williams Porcal
Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress.
European journal of medicinal chemistry 2012;58():44-9.
2012: Jose A Morales-Garcia; Valle Palomo; Angel Santos; Marina Sanz-Sancristobal; Sandra Alonso-Gil; Carmen Gil; Rosario Luna-Medina; Ana Martinez; Ana Perez-Castillo
Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo.
ACS chemical neuroscience 2012;3(11):963-71.
2012: Valle Palomo; Concepcion Perez; Daniel I Perez; Ana Perez-Castillo; Ignacio Soteras; Sandra Alonso-Gil; Nuria E Campillo; Ana Castro; Arantxa Encinas; Carmen Gil; Jose A Morales-Garcia; Ana Martinez
5-imino-1,2,4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3.
Journal of medicinal chemistry 2012;55(4):1645-61.
2012: Miriam Redondo; Cristina Val; Juan G Zarruk; José Brea; María I Cadavid; Nuria E Campillo; Placido Ceballos; María I Loza; Ana Martínez; María A Moro; Concepción Pérez; Daniel I Pérez; Ana Perez-Castillo; Carmen Gil
Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.
European journal of medicinal chemistry 2012;47(1):175-85.
2011: Ana Martinez; Carmen Gil; Daniel I Perez
Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment.
International journal of Alzheimer's disease 2011;2011():280502.
2009: Diego Castro; Lucía Boiani; Diego Benitez; Paola Hernández; Alicia Merlino; Carmen Gil; Claudio Olea-Azar; Mercedes González; Hugo Cerecetto; Williams Porcal
Anti-trypanosomatid benzofuroxans and deoxygenated analogues: synthesis using polymer-supported triphenylphosphine, biological evaluation and mechanism of action studies.
European journal of medicinal chemistry 2009;44(12):5055-65.
2009: Daniel I Perez; Santiago Conde; Concepción Pérez; Carmen Gil; Diana Simon; Francisco Wandosell; Francisco J Moreno; Josep Lluis Gelpí; F Javier Luque; Ana Martínez
Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools.
Bioorganic & medicinal chemistry 2009;17(19):6914-25.
2009: Tania Castaño; Huanchen Wang; Nuria E Campillo; Sara Ballester; Coral González-García; Javier Hernández; Concepción Pérez; Jimena Cuenca; Ana Pérez-Castillo; Ana Martínez; Oscar Huertas; José Luis Gelpí; F Javier Luque; Hengming Ke; Carmen Gil
Synthesis, structural analysis, and biological evaluation of thioxoquinazoline derivatives as phosphodiesterase 7 inhibitors.
ChemMedChem 2009;4(5):866-76.
2009: Carmen Gil; Stefan Bräse
Solid-phase synthesis of biologically active benzoannelated nitrogen heterocycles: an update.
Journal of combinatorial chemistry 2009;11(2):175-97.
2008: Ana Castro; María José Jerez; Carmen Gil; Félix Calderón; Teresa Doménech; Arsenio Nueda; Ana Martínez
CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example.
European journal of medicinal chemistry 2008;43(7):1349-59.
2008: Ana Castro; Arantxa Encinas; Carmen Gil; Stefan Bräse; Williams Porcal; Concepción Pérez; Francisco J Moreno; Ana Martínez
Non-ATP competitive glycogen synthase kinase 3beta (GSK-3beta) inhibitors: study of structural requirements for thiadiazolidinone derivatives.
Bioorganic & medicinal chemistry 2008;16(1):495-510.
2006: Ana Castro; Tania Castaño; Arantxa Encinas; Williams Porcal; Carmen Gil
Advances in the synthesis and recent therapeutic applications of 1,2,4-thiadiazole heterocycles.
Bioorganic & medicinal chemistry 2006;14(5):1644-52.
2005: Stefan Bräse; Carmen Gil; Kerstin Knepper; Viktor Zimmermann
Organic azides: an exploding diversity of a unique class of compounds.
Angewandte Chemie (International ed. in English) 2005;44(33):5188-240.
2005: Carmen Gil; Stefan Bräse
Efficient solid-phase synthesis of highly functionalized 1,4-benzodiazepin-5-one derivatives and related compounds by intramolecular aza-Wittig reactions.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(9):2680-8.
2005: Carmen Gil; Isabel Dorronsoro; Ana Castro; Ana Martinez
Good oral absorption prediction on non-nucleoside benzothiadiazine dioxide human cytomegalovirus inhibitors using combined chromatographic and neuronal network techniques.
Bioorganic & medicinal chemistry letters 2005;15(7):1919-21.
2004: Carmen Gil; Stefan Bräse
Traceless and multifunctional linkers for the generation of small molecules on solid supports.
Current opinion in chemical biology 2004;8(3):230-7.
2004: Carmen Gil; Anja Schwögler; Stefan Bräse
The synthesis of 3-substituted 6-aryl-3 H-benzo[a][1,2,3]triazinones using polymer-bound triazenes.
Journal of combinatorial chemistry 2004;6(1):38-42.
2003: Kerstin Knepper; Carmen Gil; Stefan Bräse
Natural product-like and other biologically active heterocyclic libraries using solid-phase techniques in the post-genomic era.
Combinatorial chemistry & high throughput screening 2003;6(7):673-91.
2003: Ana Martinez; Carmen Gil; Ana Castro; Concepción Pérez; Columbiana Prieto; Joaquin Otero
Benzothiadiazine dioxides (BTD) derivatives as non-nucleoside human cytomegalovirus (HCMV) inhibitors. study of structural requirements for biological activity.
Bioorganic & medicinal chemistry 2003;11(11):2395-402.
2003: Ana Martinez; Carmen Gil; Ana Castro; Ana M Bruno; Concepción Pérez; Columbiana Prieto; Joaquin Otero
Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives.
Antiviral chemistry & chemotherapy 2003;14(2):107-14.
2002: Stefan Bräse; Carmen Gil; Kerstin Knepper
The recent impact of solid-phase synthesis on medicinally relevant benzoannelated nitrogen heterocycles.
Bioorganic & medicinal chemistry 2002;10(8):2415-37.
2001: Ana Martinez; Carmen Gil; Ana Castro; Concepción Perez; M Witvrouw; C Pannecouque; Jan Balzarini; Erik De Clercq
Anti-HIV-1 activity of benzothiadiazine dioxide.
Antiviral chemistry & chemotherapy 2001;12(6):347-51.
2001: Ana Castro; MI Abasolo; Carmen Gil; Victor Segarra; Ana Martinez
CoMFA of benzyl derivatives of 2,1,3-benzo and benzothieno[3,2-alpha]thiadiazine 2,2-dioxides: clues for the design of phosphodiesterase 7 inhibitors.
European journal of medicinal chemistry 2001;36(4):333-8.
2000: Ana Martinez; Carmen Gil; Concepción Perez; Ana Castro; C Prieto; Joaquin Otero; G Andrei; R Snoeck; Jan Balzarini; Erik De Clercq
Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives.
Journal of medicinal chemistry 2000;43(17):3267-73.
2000: Ana Martinez; Carmen Gil; MI Abasolo; Ana Castro; Ana M Bruno; Concepción Perez; Columbiana Prieto; Joaquin Otero
Benzothiadiazine dioxide dibenzyl derivatives as potent human cytomegalovirus inhibitors: synthesis and comparative molecular field analysis.
Journal of medicinal chemistry 2000;43(17):3218-25.
2000: A Martínez; Ana Castro; Carmen Gil; Montserrat Miralpeix; Victor Segarra; T Doménech; Jorge Beleta; José M Palacios; Hamish Ryder; Xavier Miró; C Bonet; Josep M Casacuberta; Fernando Azorín; Benjamin Piña; P Puigdoménech
Benzyl derivatives of 2,1,3-benzo- and benzothieno[3,2-a]thiadiazine 2,2-dioxides: first phosphodiesterase 7 inhibitors.
Journal of medicinal chemistry 2000;43(4):683-9.
1999: Ana Martinez; Carmen Gil; Concepción Perez; Ana Castro; Columbiana Prieto; Joaquin Otero
Chlorophenylmethyl benzothiadiazine dioxides derivatives: potent human cytomegalovirus inhibitors.
Bioorganic & medicinal chemistry letters 1999;9(21):3133-6.
1999: Ana Martinez; A I Esteban; Ana Castro; Carmen Gil; S Conde; Graciela Andrei; Robert Snoeck; Jan Balzarini; Erik De Clercq
Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides.
Journal of medicinal chemistry 1999;42(7):1145-50.