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vincenzo alterio

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TOP 3
vincenzo alterio; Katia D'Ambrosio; Anna Di Fiore; Claudiu T Supuran; Giuseppina De Simone
Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?
vincenzo alterio; Giuseppina Ascione; Nina Dathan; Giuseppina De simone; Emma Langella; François M M Morel; Claudiu T Supuran; Francesca Viparelli; Daniela Vullo; Simona Maria Monti
Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii.
Emanuela Truppo; Daniela Vullo; annamaria sandomenico; Claudiu T Supuran; vincenzo alterio; Giuseppina De simone; Anna Di Fiore; Alessio Innocenti; Simona M Monti
Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors.

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All Publications

2012: vincenzo alterio; Katia D'Ambrosio; Anna Di Fiore; Claudiu T Supuran; Giuseppina De Simone
Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?
Chemical reviews 2012;112(8):4421-68.
2012: vincenzo alterio; Giuseppina Ascione; Nina Dathan; Giuseppina De simone; Emma Langella; François M M Morel; Claudiu T Supuran; Francesca Viparelli; Daniela Vullo; Simona Maria Monti
Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii.
Biochimie 2012;94(5):1232-41.
2012: Emanuela Truppo; Daniela Vullo; annamaria sandomenico; Claudiu T Supuran; vincenzo alterio; Giuseppina De simone; Anna Di Fiore; Alessio Innocenti; Simona M Monti
Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors.
Bioorganic & medicinal chemistry letters 2012;22(4):1560-4.
2011: Anna Di Fiore; Alfonso Maresca; Claudiu T Supuran; vincenzo alterio; Giuseppina De simone
Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II.
Chemical communications (Cambridge, England) 2011;47(42):11636-8.
2011: Stefania Correale; Luciano Pirone; Lucia Di Marcotullio; enrico de smaele; Azzura Greco; Daniela Mazzà; Marta Moretti; vincenzo alterio; Luigi Vitagliano; Sonia Di Gaetano; Alberto Gulino; Emilia Maria Pedone
Molecular organization of the cullin E3 ligase adaptor KCTD11.
Biochimie 2011;93(4):715-24.
2010: Anna Di Fiore; Emanuela Truppo; Claudiu T Supuran; vincenzo alterio; Nina Dathan; Fatemeh Bootorabi; Seppo Parkkila; Simona Maria Monti; Giuseppina De simone
Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide.
Bioorganic & medicinal chemistry letters 2010;20(17):5023-6.
2010: vincenzo alterio; Simona Maria Monti; Emanuela Truppo; Carlo Pedone; Claudiu T Supuran; Giuseppina De simone
The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex.
Organic & biomolecular chemistry 2010;8(15):3528-33.
2010: vincenzo alterio; Vincenzo Aurilia; Alessandra Romanelli; Antonietta Parracino; Michele Saviano; Sabato D'Auria; Giuseppina De simone
Crystal structure of an S-formylglutathione hydrolase from Pseudoalteromonas haloplanktis TAC125.
Biopolymers 2010;93(8):669-77.
2010: Claudiu T Supuran; Anna Di Fiore; vincenzo alterio; Simona Maria Monti; Giuseppina De Simone
Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII.
Current pharmaceutical design 2010;16(29):3246-54.
2009: Rosa Maria Vitale; vincenzo alterio; Alessio Innocenti; Jean-Yves Winum; Simona Maria Monti; Giuseppina De Simone; Claudiu T Supuran
Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors.
Journal of medicinal chemistry 2009;52(19):5990-8.
2009: vincenzo alterio; Mika Hilvo; Anna Di Fiore; Claudiu T Supuran; Peiwen Pan; Seppo Parkkila; Andrea Scaloni; Jaromir Pastorek; Silvia Pastorekova; Carlo Pedone; Andrea Scozzafava; Simona Maria Monti; Giuseppina De simone
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16233-8.
2008: Luigi Mandrich; Valeria Menchise; vincenzo alterio; Giuseppina De simone; Carlo Pedone; Mosè Rossi; Giuseppe Manco
Functional and structural features of the oxyanion hole in a thermophilic esterase from Alicyclobacillus acidocaldarius.
Proteins 2008;71(4):1721-31.
2007: vincenzo alterio; Giuseppina De simone; Simona Maria Monti; Andrea Scozzafava; Claudiu T Supuran
Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies.
Bioorganic & medicinal chemistry letters 2007;17(15):4201-7.
2006: vincenzo alterio; Rosa Maria Vitale; Simona Maria Monti; Carlo Pedone; Andrea Scozzafava; Alessandro Cecchi; Giuseppina De simone; Claudiu T Supuran
Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX.
Journal of the American Chemical Society 2006;128(25):8329-35.
2006: Mario Cappiello; vincenzo alterio; Pietro Amodeo; Antonella Del Corso; Andrea Scaloni; Carlo Pedone; Roberta Moschini; Gian Marco De Donatis; Giuseppina De simone; Umberto Mura
Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase.
Biochemistry 2006;45(10):3226-34.
2005: Valeria Menchise; Giuseppina De simone; vincenzo alterio; Anna Di Fiore; Carlo Pedone; Andrea Scozzafava; Claudiu T Supuran
Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II.
Journal of medicinal chemistry 2005;48(18):5721-7.
2004: Giuseppina De simone; Valeria Menchise; vincenzo alterio; Luigi Mandrich; Mosè Rossi; Giuseppe Manco; Carlo Pedone
The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase/lipase family.
Journal of molecular biology 2004;343(1):137-46.