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Shawn Flanagan

Research Profile

Chemicals & Drugs

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Caco-2 Cells

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Publications

TOP 3
Pamela A Welch; Vikram P Sinha; Ann L Cleverly; Christelle Darstein; Shawn Flanagan; Luna Musib
Safety, tolerability, QTc evaluation, and pharmacokinetics of single and multiple doses of enzastaurin HCl (LY317615), a protein kinase C-beta inhibitor, in healthy subjects.
Diane M Hargrove; Eric S Kendall; James M Reynolds; Aung N Lwin; John P Herich; Pamela A Smith; Bronislava R Gedulin; Shawn Flanagan; Carolyn M Jodka; Julie A Hoyt; Kevin M McCowen; David G Parkes; Christen M Anderson
Biological activity of AC3174, a peptide analog of exendin-4.
Clark Chan; Eyas Abu-Raddad; Georg Golor; Hikari Watanabe; Akira Sasaki; Kwee Poo Yeo; Danny K W Soon; Vikram P Sinha; Shawn Flanagan; Minxia M He; Stephen D Wise
Clinical pharmacokinetics of alamifovir and its metabolites.

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All Publications

2007: Pamela A Welch; Vikram P Sinha; Ann L Cleverly; Christelle Darstein; Shawn Flanagan; Luna Musib
Safety, tolerability, QTc evaluation, and pharmacokinetics of single and multiple doses of enzastaurin HCl (LY317615), a protein kinase C-beta inhibitor, in healthy subjects.
Journal of clinical pharmacology 2007;47(9):1138-51.
2007: Diane M Hargrove; Eric S Kendall; James M Reynolds; Aung N Lwin; John P Herich; Pamela A Smith; Bronislava R Gedulin; Shawn Flanagan; Carolyn M Jodka; Julie A Hoyt; Kevin M McCowen; David G Parkes; Christen M Anderson
Biological activity of AC3174, a peptide analog of exendin-4.
Regulatory peptides 2007;141(1-3):113-9.
2005: Clark Chan; Eyas Abu-Raddad; Georg Golor; Hikari Watanabe; Akira Sasaki; Kwee Poo Yeo; Danny K W Soon; Vikram P Sinha; Shawn Flanagan; Minxia M He; Stephen D Wise
Clinical pharmacokinetics of alamifovir and its metabolites.
Antimicrobial agents and chemotherapy 2005;49(5):1813-22.
2002: Shawn Flanagan; Lori H Takahashi; Xiaoli Liu; Leslie Z Benet
Contributions of saturable active secretion, passive transcellular, and paracellular diffusion to the overall transport of furosemide across adenocarcinoma (Caco-2) cells.
Journal of pharmaceutical sciences 2002;91(4):1169-77.
2002: Shawn Flanagan; Carolyn L Cummins; Miki Susanto; Xiaoli Liu; Lori H Takahashi; Leslie Z Benet
Comparison of furosemide and vinblastine secretion from cell lines overexpressing multidrug resistance protein (P-glycoprotein) and multidrug resistance-associated proteins (MRP1 and MRP2).
Pharmacology 2002;64(3):126-34.
1999: Shawn Flanagan; Leslie Z Benet
Net secretion of furosemide is subject to indomethacin inhibition, as observed in Caco-2 monolayers and excised rat jejunum.
Pharmaceutical research 1999;16(2):221-24.