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Gloria E. Borgstahl

Research Profile

Procedures

X Ray Crystallography

Concepts & Ideas

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Phenomena

Living Beings

Escherichia coli

Physiology

DNA Repair

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Publications

TOP 3
Eric A Kumar; Gloria E. Borgstahl; Chia-En A Chang; Qianyi Chen; Myungshim Kang; Smitha Kizhake; Carol Kolar; Amarnath Natarajan
The paradox of conformational constraint in the design of Cbl(TKB)-binding peptides.
Eric A Kumar; G L Lokesh; Nicholas Y Palermo; Ziyan Yuan; Gulzar Ahmad; Hamid Band; Gloria E. Borgstahl; Lin Dong; Smitha Kizhake; Carol Kolar; Amarnath Natarajan
Peptide truncation leads to a twist and an unusual increase in affinity for casitas B-lineage lymphoma tyrosine kinase binding domain.
Jason Porta; Antoine M M Schreurs; Loes M J Kroon-Batenburg; Jeffrey J Lovelace; Gloria E. Borgstahl
Processing incommensurately modulated protein diffraction data with Eval15.

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All Publications

2013: Eric A Kumar; Gloria E. Borgstahl; Chia-En A Chang; Qianyi Chen; Myungshim Kang; Smitha Kizhake; Carol Kolar; Amarnath Natarajan
The paradox of conformational constraint in the design of Cbl(TKB)-binding peptides.
Scientific reports 2013;3():1639.
2012: Eric A Kumar; G L Lokesh; Nicholas Y Palermo; Ziyan Yuan; Gulzar Ahmad; Hamid Band; Gloria E. Borgstahl; Lin Dong; Smitha Kizhake; Carol Kolar; Amarnath Natarajan
Peptide truncation leads to a twist and an unusual increase in affinity for casitas B-lineage lymphoma tyrosine kinase binding domain.
Journal of medicinal chemistry 2012;55(7):3583-7.
2011: Jason Porta; Antoine M M Schreurs; Loes M J Kroon-Batenburg; Jeffrey J Lovelace; Gloria E. Borgstahl
Processing incommensurately modulated protein diffraction data with Eval15.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 7):628-38.
2011: Artem G Lada; Gloria E. Borgstahl; Corinn E Grabow; Aishwarya Prakash; Igor Rogozin; Irina S-R Waisertreiger; Youri I Pavlov
Replication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNA.
PloS one 2011;6(9):e24848.
2011: Aishwarya Prakash; Luis A Marky; Amarnath Natarajan; Michel M Ouellette; Gloria E. Borgstahl
Identification of the DNA-Binding Domains of Human Replication Protein A That Recognize G-Quadruplex DNA.
Journal of nucleic acids 2011;2011():896947.
2011: Aishwarya Prakash; Fabien Kieken; Luis A Marky; Gloria E. Borgstahl
Stabilization of a G-Quadruplex from Unfolding by Replication Protein A Using Potassium and the Porphyrin TMPyP4.
Journal of nucleic acids 2011;2011():529828.
2010: Jason Porta; Ardeschir Vahedi-Faridi; Gloria E. Borgstahl
Structural analysis of peroxide-soaked MnSOD crystals reveals side-on binding of peroxide to active-site manganese.
Journal of molecular biology 2010;399(3):377-84.
2010: Michael G Kemp; Aaron C Mason; Aura Carreira; Joyce T Reardon; Stuart J Haring; Gloria E. Borgstahl; Stephen C Kowalczykowski; Aziz Sancar; Marc S Wold
An alternative form of replication protein a expressed in normal human tissues supports DNA repair.
The Journal of biological chemistry 2010;285(7):4788-97.
2009: Elena I Stepchenkova; Elena R Tarakhovskaya; Kathryn Spitler; Christin Frahm; Miriam R Menezes; Peter D Simone; Carol Kolar; Luis A Marky; Gloria E. Borgstahl; Youri I Pavlov
Functional study of the P32T ITPA variant associated with drug sensitivity in humans.
Journal of molecular biology 2009;392(3):602-13.
2009: Xiaoyi Deng; Aishwarya Prakash; Kajari Dhar; Gilson Baia; Carol Kolar; Greg G Oakley; Gloria E. Borgstahl
Human replication protein A-Rad52-single-stranded DNA complex: stoichiometry and evidence for strand transfer regulation by phosphorylation.
Biochemistry 2009;48(28):6633-43.
2008: Admir Kellezi; Rosslyn Grosely; Fabien Kieken; Gloria E. Borgstahl; Paul L Sorgen
Purification and reconstitution of the connexin43 carboxyl terminus attached to the 4th transmembrane domain in detergent micelles.
Protein expression and purification 2008;59(2):215-22.
2007: Xiaoyi Deng; Jeff E Habel; Venkataramen Kabaleeswaran; Edward H Snell; Marc S Wold; Gloria E. Borgstahl
Structure of the full-length human RPA14/32 complex gives insights into the mechanism of DNA binding and complex formation.
Journal of molecular biology 2007;374(4):865-76.
2007: Douglas H Juers; Jeffrey Lovelace; Henry D Bellamy; Edward H Snell; Brian W Matthews; Gloria E. Borgstahl
Changes to crystals of Escherichia coli beta-galactosidase during room-temperature/low-temperature cycling and their relation to cryo-annealing.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 11):1139-53.
2007: Emine Yikilmaz; Jason Porta; Laurie E Grove; Ardeschir Vahedi-Faridi; Yuriy Bronshteyn; Thomas C Brunold; Gloria E. Borgstahl; Anne-Frances Miller
How can a single second sphere amino acid substitution cause reduction midpoint potential changes of hundreds of millivolts?
Journal of the American Chemical Society 2007;129(32):9927-40.
2007: Gloria E. Borgstahl
How to use dynamic light scattering to improve the likelihood of growing macromolecular crystals.
Methods in molecular biology (Clifton, N.J.) 2007;363():109-29.
2006: Jason Porta; Carol Kolar; Stanislav Kozmin; Youri I Pavlov; Gloria E. Borgstahl
Structure of the orthorhombic form of human inosine triphosphate pyrophosphatase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 11):1076-81.
2005: Florian Nachon; Oluwatoyin A Asojo; Gloria E. Borgstahl; Patrick Masson; Oksana Lockridge
Structural data on the aging of diethylphosphoryl-butyrylcholinesterase.
Chemico-biological interactions 2005;157-158():408-9.
2005: Oluwatoyin A Asojo; Gaddam Goud; Kajari Dhar; Alex Loukas; Bin Zhan; Vehid Deumic; Sen Liu; Gloria E. Borgstahl; Peter J Hotez
X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection.
Journal of molecular biology 2005;346(3):801-14.
2005: Florian Nachon; Oluwatoyin A Asojo; Gloria E. Borgstahl; Patrick Masson; Oksana Lockridge
Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging.
Biochemistry 2005;44(4):1154-62.
2003: Ardeschir Vahedi-Faridi; Jeffrey Lovelace; Henry D Bellamy; Edward H Snell; Gloria E. Borgstahl
Physical and structural studies on the cryocooling of insulin crystals.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2169-82.
2003: Ardeschir Vahedi-Faridi; Jason Porta; Gloria E. Borgstahl
Improved three-dimensional growth of manganese superoxide dismutase crystals on the International Space Station.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 2):385-8.
2003: Edward H Snell; Henry D Bellamy; Gloria E. Borgstahl
Macromolecular crystal quality.
Methods in enzymology 2003;368():268-88.
2002: Doba Jackson; Kajari Dhar; James K Wahl; Marc S Wold; Gloria E. Borgstahl
Analysis of the human replication protein A:Rad52 complex: evidence for crosstalk between RPA32, RPA70, Rad52 and DNA.
Journal of molecular biology 2002;321(1):133-48.
2001: Gloria E. Borgstahl; Ardeschir Vahedi-Faridi; Jeffrey Lovelace; Henry D Bellamy; Edward H Snell
A test of macromolecular crystallization in microgravity: large well ordered insulin crystals.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 8):1204-7.
2001: W Ranatunga; Doba Jackson; R A Flowers II; Gloria E. Borgstahl
Human RAD52 protein has extreme thermal stability.
Biochemistry 2001;40(29):8557-62.
2001: W Ranatunga; Doba Jackson; Janice A Lloyd; Anthony L. Forget; Kendall L Knight; Gloria E. Borgstahl
Human RAD52 exhibits two modes of self-association.
The Journal of biological chemistry 2001;276(19):15876-80.
2001: J E Habel; Jeffrey F Ohren; Gloria E. Borgstahl
Dynamic light-scattering analysis of full-length human RPA14/32 dimer: purification, crystallization and self-association.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 2):254-9.
2000: Henry D Bellamy; Edward H Snell; Jeffrey Lovelace; M Pokross; Gloria E. Borgstahl
The high-mosaicity illusion: revealing the true physical characteristics of macromolecular crystals.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 8):986-95.
2000: Gloria E. Borgstahl; M Pokross; R Chehab; A Sekher; Edward H Snell
Cryo-trapping the six-coordinate, distorted-octahedral active site of manganese superoxide dismutase.
Journal of molecular biology 2000;296(4):951-9.
1999: J A Garlitz; Catherine Summers; Robert A Flowers; Gloria E. Borgstahl
Ethylammonium nitrate: a protein crystallization reagent.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 12):2037-8.
1998: Y Guan; M J Hickey; Gloria E. Borgstahl; RA Hallewell; James R Lepock; D O'Connor; Y Hsieh; Harry S Nick; David N Silverman; John A Tainer
Crystal structure of Y34F mutant human mitochondrial manganese superoxide dismutase and the functional role of tyrosine 34.
Biochemistry 1998;37(14):4722-30.
1997: Ulrich K Genick; Gloria E. Borgstahl; K Ng; Zhong Ren; C Pradervand; P M Burke; Vukica Srajer; Tsu-Yi Teng; Wilfried Schildkamp; Duncan E McRee; John Keith Moffat; Elizabeth D Getzoff
Structure of a protein photocycle intermediate by millisecond time-resolved crystallography.
Science (New York, N.Y.) 1997;275(5305):1471-5.
1996: Gloria E. Borgstahl; H E Parge; M J Hickey; M J Johnson; Maurice Boissinot; RA Hallewell; James R Lepock; Diane E Cabelli; John A Tainer
Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface.
Biochemistry 1996;35(14):4287-97.
1995: Gloria E. Borgstahl; D R Williams; Elizabeth D Getzoff
1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore.
Biochemistry 1995;34(19):6278-87.
1994: M Baca; Gloria E. Borgstahl; Maurice Boissinot; P M Burke; D R Williams; K A Slater; Elizabeth D Getzoff
Complete chemical structure of photoactive yellow protein: novel thioester-linked 4-hydroxycinnamyl chromophore and photocycle chemistry.
Biochemistry 1994;33(48):14369-77.
1994: Gloria E. Borgstahl; Paul H Rogers; Arthur Arnone
The 1.9 A structure of deoxy beta 4 hemoglobin. Analysis of the partitioning of quaternary-associated and ligand-induced changes in tertiary structure.
Journal of molecular biology 1994;236(3):831-43.
1994: Gloria E. Borgstahl; Paul H Rogers; Arthur Arnone
The 1.8 A structure of carbonmonoxy-beta 4 hemoglobin. Analysis of a homotetramer with the R quaternary structure of liganded alpha 2 beta 2 hemoglobin.
Journal of molecular biology 1994;236(3):817-30.
1992: Gloria E. Borgstahl; H E Parge; M J Hickey; W F Beyer; RA Hallewell; John A Tainer
The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles.
Cell 1992;71(1):107-18.