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Bernadette van den Hoogen

Research Profile

Living Beings

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Reverse Transcriptase Polymerase Chain Reaction

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N J Verkaik; R M G B Buijs-Offerman; C P de Vogel; Lot de Witte; A Hofman; V W V Jaddoe; Martin Ludlow; H A Moll; D T Nguyen; A D M E Osterhaus; A van Belkum; Bernadette van den Hoogen; Willem J B Van Wamel; H A Verbrugh; Rik de Swart
Streptococcus pneumoniae exposure is associated with human metapneumovirus seroconversion and increased susceptibility to in vitro HMPV infection.
Sander Herfst; Eefje J A Schrauwen; Miranda de Graaf; Geert van Amerongen; Bernadette van den Hoogen; Rik de Swart; Albert D M E Osterhaus; Ron A M Fouchier
Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaques.
Sander Herfst; Miranda de Graaf; Eefje J A Schrauwen; Leo Sprong; Karim Hussain; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Generation of temperature-sensitive human metapneumovirus strains that provide protective immunity in hamsters.

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All Publications

2011: N J Verkaik; R M G B Buijs-Offerman; C P de Vogel; Lot de Witte; A Hofman; V W V Jaddoe; Martin Ludlow; H A Moll; D T Nguyen; A D M E Osterhaus; A van Belkum; Bernadette van den Hoogen; Willem J B Van Wamel; H A Verbrugh; Rik de Swart
Streptococcus pneumoniae exposure is associated with human metapneumovirus seroconversion and increased susceptibility to in vitro HMPV infection.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2011;17(12):1840-4.
2008: Sander Herfst; Eefje J A Schrauwen; Miranda de Graaf; Geert van Amerongen; Bernadette van den Hoogen; Rik de Swart; Albert D M E Osterhaus; Ron A M Fouchier
Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaques.
Vaccine 2008;26(33):4224-30.
2008: Sander Herfst; Miranda de Graaf; Eefje J A Schrauwen; Leo Sprong; Karim Hussain; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Generation of temperature-sensitive human metapneumovirus strains that provide protective immunity in hamsters.
The Journal of general virology 2008;89(Pt 7):1553-62.
2008: Miranda de Graaf; Sander Herfst; Eefje J A Schrauwen; Ying Choi; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Specificity and functional interaction of the polymerase complex proteins of human and avian metapneumoviruses.
The Journal of general virology 2008;89(Pt 4):975-83.
2007: Rik de Swart; Bernadette van den Hoogen; Thijs Kuiken; Sander Herfst; Geert van Amerongen; Selma Yüksel; Leo Sprong; Albert D M E Osterhaus
Immunization of macaques with formalin-inactivated human metapneumovirus induces hypersensitivity to hMPV infection.
Vaccine 2007;25(51):8518-28.
2007: Sander Herfst; Miranda de Graaf; Eefje J A Schrauwen; Nancy D Ulbrandt; Arnita Barber Barnes; Kannaki Senthil; Albert D M E Osterhaus; Ron A M Fouchier; Bernadette van den Hoogen
Immunization of Syrian golden hamsters with F subunit vaccine of human metapneumovirus induces protection against challenge with homologous or heterologous strains.
The Journal of general virology 2007;88(Pt 10):2702-9.
2007: Miranda de Graaf; Sander Herfst; Eefje J A Schrauwen; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
An improved plaque reduction virus neutralization assay for human metapneumovirus.
Journal of virological methods 2007;143(2):169-74.
2007: Bernadette van den Hoogen
Respiratory tract infection due to human metapneumovirus among elderly patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;44(9):1159-60.
2007: Bernadette van den Hoogen; Sander Herfst; Miranda de Graaf; Leo Sprong; Rob F van Lavieren; Geert van Amerongen; Selma Yüksel; Ron A M Fouchier; Albert D M E Osterhaus; Rik de Swart
Experimental infection of macaques with human metapneumovirus induces transient protective immunity.
The Journal of general virology 2007;88(Pt 4):1251-9.
2007: Tobias Allander; Tuomas Jartti; Shawon Gupta; Hubert G M Niesters; Pasi Lehtinen; Riikka Osterback; Tytti Vuorinen; Matti Waris; Annelie Bjerkner; Annika Tiveljung-Lindell; Bernadette van den Hoogen; Timo Hyypiä; Olli Ruuskanen
Human bocavirus and acute wheezing in children.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;44(7):904-10.
2004: Sander Herfst; Miranda de Graaf; Jeanne H Schickli; Roderick S Tang; Jasmine Kaur; Chin-Fen Yang; Richard Spaete; Aurelia A Haller; Bernadette van den Hoogen; Albert D M E Osterhaus; Ron A M Fouchier
Recovery of human metapneumovirus genetic lineages a and B from cloned cDNA.
Journal of virology 2004;78(15):8264-70.
2004: Frank F A IJpma; Dennis Beekhuis; Mark F Cotton; Clarissa H Pieper; Jan L L Kimpen; Bernadette van den Hoogen; G J J van Doornum; D M E Osterhaus
Human metapneumovirus infection in hospital referred South African children.
Journal of medical virology 2004;73(3):486-93.
2004: Tuomas Jartti; Pasi Lehtinen; Tytti Vuorinen; Riikka Osterback; Bernadette van den Hoogen; Albert D M E Osterhaus; Olli Ruuskanen
Respiratory picornaviruses and respiratory syncytial virus as causative agents of acute expiratory wheezing in children.
Emerging infectious diseases 2004;10(6):1095-101.
2004: Thijs Kuiken; Bernadette van den Hoogen; Debby van Riel; Jon D Laman; Geert van Amerongen; Leo Sprong; Ron A M Fouchier; Albert D M E Osterhaus
Experimental human metapneumovirus infection of cynomolgus macaques (Macaca fascicularis) results in virus replication in ciliated epithelial cells and pneumocytes with associated lesions throughout the respiratory tract.
The American journal of pathology 2004;164(6):1893-900.
2004: Bernadette van den Hoogen; Sander Herfst; Leo Sprong; Patricia A Cane; Eduardo Forleo-Neto; Rik de Swart; Albert D M E Osterhaus; Ron A M Fouchier
Antigenic and genetic variability of human metapneumoviruses.
Emerging infectious diseases 2004;10(4):658-66.
2004: Jeroen Maertzdorf; Chiaoyin K Wang; Jennifer B Brown; Joseph D Quinto; Marla Chu; Miranda de Graaf; Bernadette van den Hoogen; Richard Spaete; Albert D M E Osterhaus; Ron A M Fouchier
Real-time reverse transcriptase PCR assay for detection of human metapneumoviruses from all known genetic lineages.
Journal of clinical microbiology 2004;42(3):981-6.
2004: Bernadette van den Hoogen; D M E Osterhaus; Ron A M Fouchier
Clinical impact and diagnosis of human metapneumovirus infection.
The Pediatric infectious disease journal 2004;23(1 Suppl):S25-32.
2003: Bernadette van den Hoogen; G J J van Doornum; John C Fockens; Jan J Cornelissen; Walter Emil Philipp Beyer; Ronald de Groot; Albert D M E Osterhaus; Ron A M Fouchier
Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients.
The Journal of infectious diseases 2003;188(10):1571-7.
2003: Ron A M Fouchier; Thijs Kuiken; Martin Schutten; Geert van Amerongen; G J J van Doornum; Bernadette van den Hoogen; Malik Peiris; Wilina Lim; Klaus Stöhr; Albert D M E Osterhaus
Aetiology: Koch's postulates fulfilled for SARS virus.
Nature 2003;423(6937):240.
2003: Jan Groen; Bernadette van den Hoogen; Chantal P Burghoorn-Maas; Anthony R Fooks; Jane Burton; Chris J S C Clegg; Herve Zeller; Albert D M E Osterhaus
Serological reactivity of baculovirus-expressed Ebola virus VP35 and nucleoproteins.
Microbes and infection / Institut Pasteur 2003;5(5):379-85.
2003: Patricia A Cane; Bernadette van den Hoogen; Suparno Chakrabarti; Christopher Fegan; A D M E Osterhaus
Human metapneumovirus in a haematopoietic stem cell transplant recipient with fatal lower respiratory tract disease.
Bone marrow transplantation 2003;31(4):309-10.
2002: Tuomas Jartti; Bernadette van den Hoogen; Roberto P Garofalo; Albert D M E Osterhaus; Olli Ruuskanen
Metapneumovirus and acute wheezing in children.
Lancet 2002;360(9343):1393-4.
2002: Rik de Swart; Thijs Kuiken; Helga H Timmerman; Geert van Amerongen; Bernadette van den Hoogen; Helma W Vos; Herman J Neijens; Arno C Andeweg; Albert D M E Osterhaus
Immunization of macaques with formalin-inactivated respiratory syncytial virus (RSV) induces interleukin-13-associated hypersensitivity to subsequent RSV infection.
Journal of virology 2002;76(22):11561-9.
2002: Bernadette van den Hoogen; Theo M Bestebroer; Albert D M E Osterhaus; Ron A M Fouchier
Analysis of the genomic sequence of a human metapneumovirus.
Virology 2002;295(1):119-32.
2001: Bernadette van den Hoogen; J C de Jong; Jan Groen; Thijs Kuiken; Ronald de Groot; Ron A M Fouchier; Albert D M E Osterhaus
A newly discovered human pneumovirus isolated from young children with respiratory tract disease.
Nature medicine 2001;7(6):719-24.
2001: Rik de Swart; Yassin Nur; Abdallah Musa Abdallah; H Kruining; H Sittana El Mubarak; SA Ibrahim; Bernadette van den Hoogen; Jan Groen; Albert D M E Osterhaus
Combination of reverse transcriptase PCR analysis and immunoglobulin M detection on filter paper blood samples allows diagnostic and epidemiological studies of measles.
Journal of clinical microbiology 2001;39(1):270-3.
2000: Martin Schutten; Bernadette van den Hoogen; Marchina E Van Der Ende; Rob A Gruters; Albert D M E Osterhaus; Hubert G M Niesters
Development of a real-time quantitative RT-PCR for the detection of HIV-2 RNA in plasma.
Journal of virological methods 2000;88(1):81-7.