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Penny Jeggo

Research Profile

Physiology

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Publications

TOP 3
Eileen Pernot; Roel Quintens; Kai Rothkamm; Laure Sabatier; Soile Tapio; Sarah Baatout; Mohammed Abderrafi Benotmane; Eric Blanchardon; Simon Bouffler; Florent de Vathaire; Houssein El Saghire; Maria Gomolka; Anne Guertler; Janet Hall; Mats Harms-Ringdahl; Penny Jeggo; Michaela Kreuzer; dominique laurier; Carita Lindholm; Radhia Mkacher; Elisabeth Cardis
Ionizing radiation biomarkers for potential use in epidemiological studies.
Lisa Woodbine; A Shibata; H Brunton; ALI GOODARZI; Penny Jeggo
Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair.
ALI GOODARZI; Penny Jeggo; Markus Lobrich
The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.

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All Publications

2012: Eileen Pernot; Roel Quintens; Kai Rothkamm; Laure Sabatier; Soile Tapio; Sarah Baatout; Mohammed Abderrafi Benotmane; Eric Blanchardon; Simon Bouffler; Florent de Vathaire; Houssein El Saghire; Maria Gomolka; Anne Guertler; Janet Hall; Mats Harms-Ringdahl; Penny Jeggo; Michaela Kreuzer; dominique laurier; Carita Lindholm; Radhia Mkacher; Elisabeth Cardis
Ionizing radiation biomarkers for potential use in epidemiological studies.
Mutation research 2012;751(2):258-86.
2011: Lisa Woodbine; A Shibata; H Brunton; ALI GOODARZI; Penny Jeggo
Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair.
Nucleic acids research 2011;39(16):6986-97.
2010: ALI GOODARZI; Penny Jeggo; Markus Lobrich
The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.
DNA repair 2010;9(12):1273-82.
2010: Penny Jeggo
A break is not the End; insight into the damage response to DNA double strand breaks.
DNA repair 2010;9(12):1217-8.
2010: Penny Jeggo
The role of the DNA damage response mechanisms after low-dose radiation exposure and a consideration of potentially sensitive individuals.
Radiation research 2010;174(6):825-32.
2002: Philippa L Roddam; Sara Rollinson; Mark O'Driscoll; Penny Jeggo; Andrew Jack; Gareth J Morgan
Genetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class switch recombination.
Journal of medical genetics 2002;39(12):900-5.
2001: Y Marcou; Alan D D'Andrea; Penny Jeggo; P N Plowman
Normal cellular radiosensitivity in an adult Fanconi anaemia patient with marked clinical radiosensitivity.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2001;60(1):75-9.
2000: Andrew R Gennery; Andrew J Cant; Penny Jeggo
Immunodeficiency associated with DNA repair defects.
Clinical and experimental immunology 2000;121(1):1-7.
1999: EC Woudstra; Antonius W T Konings; Penny Jeggo; Harm H Kampinga
Role of DNA-PK subunits in radiosensitization by hyperthermia.
Radiation research 1999;152(2):214-8.
1996: F Liang; P J Romanienko; David Weaver; Penny Jeggo; Maria Jasin
Chromosomal double-strand break repair in Ku80-deficient cells.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):8929-33.
1995: S P Jackson; Penny Jeggo
DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.
Trends in biochemical sciences 1995;20(10):412-5.
1995: Malgorzata Z Zdzienicka; W Jongmans; M Oshimura; A Priestley; G F Whitmore; Penny Jeggo
Complementation analysis of the murine scid cell line.
Radiation research 1995;143(3):238-44.
1995: Larry H Thompson; Penny Jeggo
Nomenclature of human genes involved in ionizing radiation sensitivity.
Mutation research 1995;337(2):131-4.
1995: G M Ross; J J Eady; N P Mithal; C Bush; GG Steel; Penny Jeggo; Trevor J McMillan
DNA strand break rejoining defect in xrs-6 is complemented by transfection with the human Ku80 gene.
Cancer research 1995;55(6):1235-8.
1994: Penny Jeggo; Antony M Carr; Alan Lehmann
Cloning human DNA repair genes.
International journal of radiation biology 1994;66(5):573-7.
1993: C B Harvey; M F Fox; Penny Jeggo; N Mantei; Sue Povey; Dallas M Swallow
Regional localization of the lactase-phlorizin hydrolase gene, LCT, to chromosome 2q21.
Annals of human genetics 1993;57(Pt 3):179-85.
1993: Jochen Dahm-Daphi; Ekkehard Dikomey; C Pyttlik; Penny Jeggo
Reparable and non-reparable DNA strand breaks induced by X-irradiation in CHO K1 cells and the radiosensitive mutants xrs1 and xrs5.
International journal of radiation biology 1993;64(1):19-26.
1990: Penny Jeggo
Studies on mammalian mutants defective in rejoining double-strand breaks in DNA.
Mutation research 1990;239(1):1-16.
1989: Penny Jeggo; K Caldecott; S Pidsley; G R Banks
Sensitivity of Chinese hamster ovary mutants defective in DNA double strand break repair to topoisomerase II inhibitors.
Cancer research 1989;49(24 Pt 1):7057-63.
1989: J Smith-Ravin; Penny Jeggo
Use of damaged plasmid to study DNA repair in X-ray sensitive (xrs) strains of Chinese hamster ovary (CHO) cells.
International journal of radiation biology 1989;56(6):951-61.
1989: Penny Jeggo; J Smith-Ravin
Decreased stable transfection frequencies of six X-ray-sensitive CHO strains, all members of the xrs complementation group.
Mutation research 1989;218(2):75-86.
1987: Fotini Gounari; G R Banks; Khashayarsha Khazaie; Penny Jeggo; R Holliday
Gene reactivation: a tool for the isolation of mammalian DNA methylation mutants.
Genes & development 1987;1(9):899-912.
1987: Peter E Bryant; D A Birch; Penny Jeggo
High chromosomal sensitivity of Chinese hamster xrs 5 cells to restriction endonuclease induced DNA double-strand breaks.
International journal of radiation biology and related studies in physics, chemistry, and medicine 1987;52(4):537-54.
1986: L M Kemp; Penny Jeggo
Radiation-induced chromosome damage in X-ray-sensitive mutants (xrs) of the Chinese hamster ovary cell line.
Mutation research 1986;166(3):255-63.
1986: Penny Jeggo; R Holliday
Azacytidine-induced reactivation of a DNA repair gene in Chinese hamster ovary cells.
Molecular and cellular biology 1986;6(8):2944-9.
1985: Penny Jeggo
Genetic analysis of X-ray-sensitive mutants of the CHO cell line.
Mutation research 1985;146(3):265-70.
1985: Penny Jeggo
X-ray sensitive mutants of Chinese hamster ovary cell line: radio-sensitivity of DNA synthesis.
Mutation research 1985;145(3):171-6.
1985: R Holliday; Penny Jeggo
Mechanisms for changing gene expression and their possible relationship to carcinogenesis.
Cancer surveys 1985;4(3):557-81.
1984: L M Kemp; S G Sedgwick; Penny Jeggo
X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining.
Mutation research 1984;132(5-6):189-96.
1983: Penny Jeggo; L M Kemp
X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents.
Mutation research 1983;112(6):313-27.
1982: Penny Jeggo; L M Kemp; R Holliday
The application of the microbial "tooth-pick" technique to somatic cell genetics, and its use in the isolation of X-ray sensitive mutants of Chinese hamster ovary cells.
Biochimie 1982;64(8-9):713-5.
1975: Penny Jeggo; G R Banks
DNA polymerase of Ustilago maydis: partial characterization of the enzyme and a pol 1 mutation.
Molecular & general genetics : MGG 1975;142(3):209-24.
1973: Penny Jeggo; P Unrau; G R Banks; R Holliday
A temperature sensitive DNA polymerase mutant of Ustilago maydis.
Nature: New biology 1973;242(114):14-6.