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Beatriz Carvalho

Research Profile

Disorders

Procedures

Comparative Genomic Hybridization

Physiology

Concepts & Ideas

Gene Dosage

Devices

Oligonucleotide Array Sequence Analysis

Anatomy

Chemicals & Drugs

Genes & Molecular Sequences

Genome, Human

Phenomena

Nucleic Acid Hybridization

Co-author Network

Publications

TOP 3
Nicole C T van Grieken; L C Ward; T Yoshikawa; S L Zhang; T Aoyma; T Arai; D Bottomley; Tineke E Buffart; Beatriz Carvalho; P A Chambers; K Das; Daniëlle A M Heideman; I Inam; Y Kameda; T Lim; Gerrit A Meijer; Y Miyagi; B Pang; I B Tan; P Tan; A Tsuburaya; Heike Grabsch
KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: Results from a large international multicentre study.
Anke H Sillars-Hardebol; Marianne Tijssen; Mark A van de Wiel; Fredrik Pontén; Jeroen A M Beliën; Beatriz Carvalho; Meike de Wit; Pien M Delis-van Diemen; Remond J A Fijneman; Gerrit A Meijer
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression.
Adam R Morris; Koos Rooijers; Anne S Bolijn; Arnold Bos; Beatriz Carvalho; Begoña Diosdado; Ran Elkon; Gerrit A Meijer; Reuven Agami
Alternative cleavage and polyadenylation during colorectal cancer development.

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All Publications

2013: Nicole C T van Grieken; L C Ward; T Yoshikawa; S L Zhang; T Aoyma; T Arai; D Bottomley; Tineke E Buffart; Beatriz Carvalho; P A Chambers; K Das; Daniëlle A M Heideman; I Inam; Y Kameda; T Lim; Gerrit A Meijer; Y Miyagi; B Pang; I B Tan; P Tan; A Tsuburaya; Heike Grabsch
KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: Results from a large international multicentre study.
British journal of cancer 2013;108(7):1495-501.
2012: Anke H Sillars-Hardebol; Marianne Tijssen; Mark A van de Wiel; Fredrik Pontén; Jeroen A M Beliën; Beatriz Carvalho; Meike de Wit; Pien M Delis-van Diemen; Remond J A Fijneman; Gerrit A Meijer
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression.
Gut 2012;61(11):1568-75.
2012: Adam R Morris; Koos Rooijers; Anne S Bolijn; Arnold Bos; Beatriz Carvalho; Begoña Diosdado; Ran Elkon; Gerrit A Meijer; Reuven Agami
Alternative cleavage and polyadenylation during colorectal cancer development.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(19):5256-66.
2012: Quirinus J M Voorham; Bauke Ylstra; Tomio Arai; Beatriz Carvalho; Adriaan P de Bruïne; Heike Grabsch; Ekaterina S. Jordanova; Martin Kliment; Sandra Mongera; Chris J J Mulder; Philip Quirke; Bjorn J Rembacken; Eveline J A Rondagh; Silvia Sanduleanu; Angela J Spiertz; Mark A van de Wiel; Manon van Engeland; Nicole C T van Grieken; Gerrit A Meijer
Chromosome 5q loss in colorectal flat adenomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(17):4560-9.
2012: Joana Carvalho; Begoña Diosdado; Heike Grabsch; Gerrit Meijer; Patricia M Pereira; Manuel A S Santos; Raquel Seruca; Sónia Sousa; Marianne Tijssen; Nicole C van Grieken; Tineke E Buffart; Beatriz Carvalho; Carla Oliveira
Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer.
The Journal of pathology 2012;228(1):31-44.
2012: Linda J W Bosch; Beatriz Carvalho; Joost Louwagie; Sandra Mongera; Chris J J Mulder; Frank A Oort; Maarten T Penning; Manon van Engeland; Sietze T van Turenhout; Jochim S Terhaar Sive Droste; Gerrit A Meijer
Analytical sensitivity and stability of DNA methylation testing in stool samples for colorectal cancer detection.
Cellular oncology (Dordrecht) 2012;35(4):309-15.
2012: Anke H Sillars-Hardebol; Marianne Tijssen; Mark A van de Wiel; Gerrit A Meijer; Fredrik Pontén; Jeroen A M Beliën; Beatriz Carvalho; Meike de Wit; Pien M Delis-van Diemen; Remond J A Fijneman
CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression.
Cellular oncology (Dordrecht) 2012;35(4):293-300.
2012: Meike de Wit; Pien M Delis-van Diemen; Jeroen A M Belien; Beatriz Carvalho; Connie R Jimenez; Gerrit A Meijer; Sandra Mongera; Sanjay Navani; Sander R Piersma; Fredrik Pontén; Maindad Vikas; Remond J A Fijneman
Cell surface proteomics identifies glucose transporter type 1 and prion protein as candidate biomarkers for colorectal adenoma-to-carcinoma progression.
Gut 2012;61(6):855-64.
2012: Linda J W Bosch; Beatriz Carvalho; Veerle M H Coupé; Madeleine Grooteclaes; Daisy M A E Jonkers; Carolina A J Khalid-de Bakker; Joost Louwagie; Ad A M Masclee; Veerle Melotte; Sandra Mongera; Chris J Mulder; Maarten Neerincx; Frank A Oort; Wim van Criekinge; Manon van Engeland; Jochim S Terhaar sive Droste; Gerrit A Meijer
DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT.
Cancer prevention research (Philadelphia, Pa.) 2012;5(3):464-72.
2012: Beatriz Carvalho; Remond J A Fijneman; Sandra Mongera; Askar Obulkasim; Cindy Postma; Anke H Sillars-Hardebol; Wim van Criekinge; Mark A van de Wiel; Bauke Ylstra; Jochim Terhaar Sive Droste; Gerrit A Meijer
Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism.
Cellular oncology (Dordrecht) 2012;35(1):53-63.
2012: Anke H Sillars-Hardebol; Marianne Tijssen; Mark A van de Wiel; Fredrik Pontén; Jeroen Am Beliën; Beatriz Carvalho; Meike de Wit; Pien M Delis-van Diemen; Remond J A Fijneman; Gerrit A Meijer
BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain.
The Journal of pathology 2012;226(3):442-50.
2012: Quirinus J M Voorham; Beatriz Carvalho; Bart Claes; Heike Grabsch; Martin Kliment; Diether Lambrechts; Sandra Mongera; Chris J J Mulder; Philip Quirke; Bjorn Rembacken; Angela J Spiertz; Mark A van de Wiel; Manon van Engeland; Nicole C T van Grieken; Gerrit A Meijer
Comprehensive mutation analysis in colorectal flat adenomas.
PloS one 2012;7(7):e41963.
2012: Tineke E Buffart; Beatriz Carvalho; Heike Grabsch; Elma Meershoek-Klein Kranenbarg; Marianne Tijssen; Cornelis J H van de Velde; Nicole C T van Grieken; Wessel N van Wieringen; Hendrik Verheul; Bauke Ylstra; Gerrit A Meijer
Losses of chromosome 5q and 14q are associated with favorable clinical outcome of patients with gastric cancer.
The oncologist 2012;17(5):653-62.
2012: Anke H Sillars-Hardebol; Manon van Engeland; Beatriz Carvalho; Remond J A Fijneman; Gerrit A Meijer
The adenoma hunt in colorectal cancer screening: defining the target.
The Journal of pathology 2012;226(1):1-6.
2011: R P M Brosens; Tineke E Buffart; Beatriz Carvalho; Miguel A Cuesta; Alexander F Engel; Heike Grabsch; J C Haan; Philip Quirke; Bauke Ylstra; E J T H Belt; Gerrit A Meijer
Deletion of chromosome 4q predicts outcome in stage II colon cancer patients.
Cellular oncology (Dordrecht) 2011;34(3):215-23.
2011: Linda J W Bosch; Beatriz Carvalho; Remond J A Fijneman; Connie R Jimenez; HERBERT PINEDO; Manon van Engeland; Gerrit A Meijer
Molecular tests for colorectal cancer screening.
Clinical colorectal cancer 2011;10(1):8-23.
2011: Tineke E Buffart; Melanie Louw; Nicole C T van Grieken; Marloes R Tijssen; Beatriz Carvalho; Bauke Ylstra; Heike Grabsch; Chris J J Mulder; Cornelis J H van de Velde; Schalk W van der Merwe; Gerrit A Meijer
Gastric cancers of Western European and African patients show different patterns of genomic instability.
BMC medical genomics 2011;4():7.
2010: Rebecca P M Brosens; Josien C Haan; Beatriz Carvalho; François Rustenburg; Heike Grabsch; Philip Quirke; Alexander F Engel; Miguel A Cuesta; Nicola Maughan; Marcel Flens; Gerrit A Meijer; Bauke Ylstra
Candidate driver genes in focal chromosomal aberrations of stage II colon cancer.
The Journal of pathology 2010;221(4):411-24.
2010: Jakob Albrethsen; Jaco C Knol; Sander R Piersma; Thang V Pham; Meike de Wit; Sandra Mongera; Beatriz Carvalho; Hendrik Verheul; Remond J A Fijneman; Gerrit A Meijer; Connie R Jimenez
Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression.
Molecular & cellular proteomics : MCP 2010;9(5):988-1005.
2010: Anke H Sillars-Hardebol; Beatriz Carvalho; Meike de Wit; Cindy Postma; Pien M Delis-van Diemen; Sandra Mongera; Bauke Ylstra; Mark A van de Wiel; Gerrit A Meijer; Remond J A Fijneman
Identification of key genes for carcinogenic pathways associated with colorectal adenoma-to-carcinoma progression.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2010;31(2):89-96.
2010: Begoña Diosdado; Tineke E Buffart; Russell Watkins; Beatriz Carvalho; Bauke Ylstra; Marianne Tijssen; Anne S Bolijn; Fraser Lewis; Karen Maude; Caroline Verbeke; Iris Nagtegaal; Heike Grabsch; Chris J J Mulder; Phil Quirke; Peter Howdle; Gerrit A Meijer
High-resolution array comparative genomic hybridization in sporadic and celiac disease-related small bowel adenocarcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(5):1391-401.
2010: R P M Brosens; E J T H Belt; J C Haan; T E Buffart; Beatriz Carvalho; Heike Grabsch; Philip Quirke; Miguel A Cuesta; Alexander F Engel; Bauke Ylstra; Gerrit A Meijer
Deletion of chromosome 4q predicts outcome in stage II colon cancer patients.
Analytical cellular pathology (Amsterdam) 2010;33(2):95-104.
2009: Tineke E Buffart; Nicole C T van Grieken; Marloes R Tijssen; Jordy Coffa; Bauke Ylstra; Heike Grabsch; Cornelis J H van de Velde; Beatriz Carvalho; Gerrit A Meijer
High resolution analysis of DNA copy-number aberrations of chromosomes 8, 13, and 20 in gastric cancers.
Virchows Archiv : an international journal of pathology 2009;455(3):213-23.
2009: B Diosdado; Mark A van de Wiel; J S Terhaar Sive Droste; S Mongera; C Postma; W J H J Meijerink; Beatriz Carvalho; Gerrit A Meijer
MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression.
British journal of cancer 2009;101(4):707-14.
2009: Sarah Derks; Linda J W Bosch; Hanneke E C Niessen; Peter Moerkerk; Sandra M van den Bosch; Beatriz Carvalho; Sandra Mongera; J Willem Voncken; Gerrit A Meijer; Adriaan P de Bruïne; James G Herman; Manon van Engeland
Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.
Carcinogenesis 2009;30(6):1041-8.
2009: Cindy Postma; M Koopman; Tineke E Buffart; Paul P Eijk; Beatriz Carvalho; G J Peters; Bauke Ylstra; J H J M van Krieken; C J A Punt; Gerrit A Meijer
DNA copy number profiles of primary tumors as predictors of response to chemotherapy in advanced colorectal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(6):1048-56.
2009: Tineke E Buffart; Marloes R Tijssen; Jamila El-Bchiri; Alex Duval; Mark A van de Wiel; Bauke Ylstra; Gerrit A Meijer; Beatriz Carvalho
NMD inhibition fails to identify tumour suppressor genes in microsatellite stable gastric cancer cell lines.
BMC medical genomics 2009;2():39.
2008: Tineke E Buffart; Renée M Overmeer; Renske D M Steenbergen; Marloes R Tijssen; N C T van Grieken; Peter J F Snijders; Heike Grabsch; C J H van de Velde; Beatriz Carvalho; Gerrit A Meijer
MAL promoter hypermethylation as a novel prognostic marker in gastric cancer.
British journal of cancer 2008;99(11):1802-7.
2008: Sarah Derks; Cindy Postma; Beatriz Carvalho; Sandra M van den Bosch; Peter Moerkerk; James G Herman; Matty P Weijenberg; Adriaan P de Bruïne; Gerrit A Meijer; Manon van Engeland
Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
Carcinogenesis 2008;29(2):434-9.
2008: Jordy Coffa; Mark A van de Wiel; Begoña Diosdado; Beatriz Carvalho; Jan Schouten; Gerrit A Meijer
MLPAnalyzer: data analysis tool for reliable automated normalization of MLPA fragment data.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2008;30(4):323-35.
2007: Remond J A Fijneman; Beatriz Carvalho; Cindy Postma; Sandra Mongera; Victor W M van Hinsbergh; Gerrit A Meijer
Loss of 1p36, gain of 8q24, and loss of 9q34 are associated with stroma percentage of colorectal cancer.
Cancer letters 2007;258(2):223-9.
2007: Bradley P Coe; Bauke Ylstra; Beatriz Carvalho; Gerrit A Meijer; Calum MacAulay; Wan L Lam
Resolving the resolution of array CGH.
Genomics 2007;89(5):647-53.
2007: K Jong; Elena Marchiori; Aad W van der Vaart; Suet-Feung Chin; Beatriz Carvalho; Marloes R Tijssen; Paul P Eijk; Paul van den IJssel; Heike Grabsch; Philip Quirke; Joost Oudejans; Gerrit A Meijer; C Caldas; Bauke Ylstra
Cross-platform array comparative genomic hybridization meta-analysis separates hematopoietic and mesenchymal from epithelial tumors.
Oncogene 2007;26(10):1499-506.
2007: Tineke E Buffart; Beatriz Carvalho; Thomas Mons; Rui M Reis; Cátia Moutinho; Paula Silva; Nicole C T van Grieken; Michael Vieth; Manfred Stolte; Cornelis J H van de Velde; Evelin Schrock; Anja Matthaei; Bauke Ylstra; Fátima Carneiro; Gerrit A Meijer
DNA copy number profiles of gastric cancer precursor lesions.
BMC genomics 2007;8():345.
2007: Tineke E Buffart; Marloes R Tijssen; Thijs Krugers; Beatriz Carvalho; Serge J Smeets; Ruud H Brakenhoff; Heike Grabsch; Gerrit A Meijer; Henry B Sadowski; Bauke Ylstra
DNA quality assessment for array CGH by isothermal whole genome amplification.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(4):351-9.
2007: Tineke E Buffart; Beatriz Carvalho; E Hopmans; V Brehm; Elma Klein Kranenbarg; T B M Schaaij-Visser; Paul P Eijk; Nicole C T van Grieken; Bauke Ylstra; Cornelis J H van de Velde; Gerrit A Meijer
Gastric cancers in young and elderly patients show different genomic profiles.
The Journal of pathology 2007;211(1):45-51.
2006: Beatriz Carvalho; Tineke E Buffart; Rui M Reis; Thomas Mons; Cátia Moutinho; Paula Silva; Nicole C T van Grieken; Heike Grabsch; Cornelis J H van de Velde; Bauke Ylstra; Gerrit A Meijer; Fátima Carneiro
Mixed gastric carcinomas show similar chromosomal aberrations in both their diffuse and glandular components.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2006;28(5-6):283-94.
2006: Sarah Derks; Cindy Postma; Peter Moerkerk; Sandra M van den Bosch; Beatriz Carvalho; Mario A J A Hermsen; Walter Giaretti; James G Herman; Matty P Weijenberg; Adriaan P de Bruïne; Gerrit A Meijer; Manon van Engeland
Promoter methylation precedes chromosomal alterations in colorectal cancer development.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2006;28(5-6):247-57.
2006: Bauke Ylstra; Paul van den IJssel; Beatriz Carvalho; Ruud H Brakenhoff; Gerrit A Meijer
BAC to the future! or oligonucleotides: a perspective for micro array comparative genomic hybridization (array CGH).
Nucleic acids research 2006;34(2):445-50.
2005: Paul van den IJssel; Marloes R Tijssen; Suet-Feung Chin; Paul P Eijk; Beatriz Carvalho; Erik Hopmans; Henne Holstege; Dhinoth Kumar Bangarusamy; Jos Jonkers; Gerrit A Meijer; Carlos Caldas; Bauke Ylstra
Human and mouse oligonucleotide-based array CGH.
Nucleic acids research 2005;33(22):e192.
2005: Tineke E Buffart; Jordy Coffa; Mario A J A Hermsen; Beatriz Carvalho; J R M van der Sijp; Bauke Ylstra; Gerard Pals; Jan P Schouten; Gerrit A Meijer
DNA copy number changes at 8q11-24 in metastasized colorectal cancer.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2005;27(1):57-65.
2004: Beatriz Carvalho; E Ouwerkerk; Gerrit A Meijer; Bauke Ylstra
High resolution microarray comparative genomic hybridisation analysis using spotted oligonucleotides.
Journal of clinical pathology 2004;57(6):644-6.