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Jo Demeester

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Oliwia Andries; Stefaan C De Smedt; Jo Demeester; Luc Peelman; Marina De Filette; Mario Van Poucke; Niek N Sanders
Innate immune response and programmed cell death following carrier-mediated delivery of unmodified mRNA to respiratory cells.
Nathalie Symens; Stefaan C De Smedt; Jo Demeester; Bart Lucas; Joanna Rejman; Katrien Remaut
Noncoding DNA in lipofection of HeLa cells-a few insights.
Broes Naeye; Christian Vanhove; Kevin Braeckmans; Vicky Caveliers; Stefaan C De Smedt; Jo Demeester; Benedicte Descamps; Hendrik Deschout; Tony Lahoutte; Koen Raemdonck
In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier.

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2013: Oliwia Andries; Stefaan C De Smedt; Jo Demeester; Luc Peelman; Marina De Filette; Mario Van Poucke; Niek N Sanders
Innate immune response and programmed cell death following carrier-mediated delivery of unmodified mRNA to respiratory cells.
Journal of controlled release : official journal of the Controlled Release Society 2013;167(2):157-66.
2013: Nathalie Symens; Stefaan C De Smedt; Jo Demeester; Bart Lucas; Joanna Rejman; Katrien Remaut
Noncoding DNA in lipofection of HeLa cells-a few insights.
Molecular pharmaceutics 2013;10(3):1070-9.
2013: Broes Naeye; Christian Vanhove; Kevin Braeckmans; Vicky Caveliers; Stefaan C De Smedt; Jo Demeester; Benedicte Descamps; Hendrik Deschout; Tony Lahoutte; Koen Raemdonck
In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier.
Biomaterials 2013;34(9):2350-8.
2012: Zanna Hyvönen; Bart Lucas; Joanna Rejman; Marika Ruponen; Dries Vercauteren; Stefaan De Smedt; Jo Demeester; Vesa Hämäläinen; Kevin Braeckmans
Elucidating the pre- and post-nuclear intracellular processing of 1,4-dihydropyridine based gene delivery carriers.
Journal of controlled release : official journal of the Controlled Release Society 2012;162(1):167-75.
2012: Dries Vercauteren; Stefaan C De Smedt; Jo Demeester; Thomas F Martens; Joanna Rejman; Kevin Braeckmans
On the cellular processing of non-viral nanomedicines for nucleic acid delivery: mechanisms and methods.
Journal of controlled release : official journal of the Controlled Release Society 2012;161(2):566-81.
2012: Stefaan J Soenen; Stefaan C De Smedt; Jo Demeester; Kevin Braeckmans
The cytotoxic effects of polymer-coated quantum dots and restrictions for live cell applications.
Biomaterials 2012;33(19):4882-8.
2012: Marie-Luce De Temmerman; Jo Demeester; Stefaan C De Smedt; Joanna Rejman
Tailoring layer-by-layer capsules for biomedical applications.
Nanomedicine (London, England) 2012;7(5):771-88.
2012: Marie-Luce De Temmerman; Jo Demeester; Bruno Gander; Johan Grooten; Claude Libert; Joanna Rejman; Roosmarijn Vandenbroucke; Stefaan De Koker; Stefaan C De Smedt
Polyelectrolyte LbL microcapsules versus PLGA microparticles for immunization with a protein antigen.
Journal of controlled release : official journal of the Controlled Release Society 2012;158(2):233-9.
2012: B Naeye; Koen Raemdonck; Katrien Remaut; Jo Demeester; Stefaan C De Smedt
Matrix systems for siRNA delivery.
Current topics in medicinal chemistry 2012;12(2):89-96.
2012: Chaobo Huang; Joanna Rejman; Stefaan J Soenen; Marleen Temmerman; Serge Van Calenbergh; Ellen van Gulck; Guido Vanham; Hans Verstraelen; Chris Vervaet; Tom Coenye; Jo Demeester; Stefaan C De Smedt
Electrospun cellulose acetate phthalate fibers for semen induced anti-HIV vaginal drug delivery.
Biomaterials 2012;33(3):962-9.
2011: Bart Geers; Ine Lentacker; Stephen Meairs; Niek N Sanders; Angelika Alonso; Jo Demeester; Stefaan C De Smedt
Elucidating the mechanisms behind sonoporation with adeno-associated virus-loaded microbubbles.
Molecular pharmaceutics 2011;8(6):2244-51.
2011: Broes Naeye; Magnus Röding; Mats Rudemo; Kevin Braeckmans; Stefaan C De Smedt; Joris Delanghe; Jo Demeester; Hendrik Deschout; Katrien Devreese; Koen Raemdonck
Hemocompatibility of siRNA loaded dextran nanogels.
Biomaterials 2011;32(34):9120-7.
2011: Marie-Luce De Temmerman; Jo Demeester; Heleen Dewitte; Ine Lentacker; Claude Libert; Bart Lucas; Stefaan C De Smedt; Roosmarijn Vandenbroucke; Joanna Rejman
mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells.
Biomaterials 2011;32(34):9128-35.
2011: Dries Vercauteren; Stefaan C De Smedt; Jo Demeester; Hendrik Deschout; Johan F J Engbersen; Arwyn T Jones; Katrien Remaut; Kevin Braeckmans
Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines.
ACS nano 2011;5(10):7874-84.
2011: Nathalie Symens; Rudolf Walczak; Stefaan C De Smedt; Jo Demeester; Iain Mattaj; Katrien Remaut
Nuclear inclusion of nontargeted and chromatin-targeted polystyrene beads and plasmid DNA containing nanoparticles.
Molecular pharmaceutics 2011;8(5):1757-66.
2011: Marie-Luce De Temmerman; Jo Demeester; Bruno Gander; Darrell J Irvine; Joanna Rejman; Stefaan C De Smedt
Particulate vaccines: on the quest for optimal delivery and immune response.
Drug discovery today 2011;16(13-14):569-82.
2011: Marie-Luce De Temmerman; Jo Demeester; Johan Grooten; Joanna Rejman; Chris Vervaet; Thomas De Beer; Stefaan C De Smedt
Lyophilization of protein-loaded polyelectrolyte microcapsules.
Pharmaceutical research 2011;28(7):1765-73.
2011: Bart Geers; Ine Lentacker; Stephen Meairs; Niek N Sanders; Jo Demeester; Stefaan C De Smedt
Self-assembled liposome-loaded microbubbles: The missing link for safe and efficient ultrasound triggered drug-delivery.
Journal of controlled release : official journal of the Controlled Release Society 2011;152(2):249-56.
2011: Chaobo Huang; Stefaan J Soenen; Joanna Rejman; Bart Lucas; Kevin Braeckmans; Jo Demeester; Stefaan C De Smedt
Stimuli-responsive electrospun fibers and their applications.
Chemical Society reviews 2011;40(5):2417-34.
2011: Marie-Luce De Temmerman; Jo Demeester; Filip De Vos; Stefaan C De Smedt
Encapsulation performance of layer-by-layer microcapsules for proteins.
Biomacromolecules 2011;12(4):1283-9.
2011: Geertrui Tavernier; Oliwia Andries; Jo Demeester; Niek N Sanders; Stefaan C De Smedt; Joanna Rejman
mRNA as gene therapeutic: how to control protein expression.
Journal of controlled release : official journal of the Controlled Release Society 2011;150(3):238-47.
2010: N Symens; R Walzack; Jo Demeester; I Mattaj; Stefaan C De Smedt; Katrien Remaut
Nuclear inclusion of inert and chromatin-targeted polystyrene spheres and plasmid DNA containing nanoparticles.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e96-8.
2010: Koen Raemdonck; B Naeye; A Høgset; Jo Demeester; Stefaan C De Smedt
Biodegradable dextran nanogels as functional carriers for the intracellular delivery of small interfering RNA.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e95-6.
2010: B Naeye; Koen Raemdonck; Jo Demeester; Stefaan C De Smedt
Interactions of siRNA loaded dextran nanogel with blood cells.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e90-1.
2010: Bart Geers; Ine Lentacker; Angelika Alonso; Stephen Meairs; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Adeno-associated virus loaded microbubbles as a tool for targeted gene delivery.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e59.
2010: Bart Geers; Ine Lentacker; Steven Cool; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Ultrasound responsive doxorubicin-loaded microbubbles; towards an easy applicable drug delivery platform.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e59-60.
2010: M L De Temmerman; Filip De Vos; Jo Demeester; Stefaan C De Smedt
Protein encapsulation in polyelectrolyte microcapsules for antigen delivery.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e54-6.
2010: Katrien Forier; Anne-Sophie Messiaen; Tom Coenye; Hans Nelis; Shari Celen; Serge Van Calenbergh; Stefaan De Smedt; Jo Demeester; Kevin Braeckmans
Transport and delivery of antimicrobial agents in Burkholderia biofilms.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e35-6.
2010: Chaobo Huang; Bart Lucas; Chris Vervaet; Kevin Braeckmans; Serge Van Calenbergh; Izet Karalic; M Vandewoestyne; Dieter Deforce; Jo Demeester; Stefaan C De Smedt
Unbreakable codes in electrospun fibers to stop medicine counterfeiting.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e13-5.
2010: Ine Lentacker; Bart Geers; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Tumor cell killing efficiency of doxorubicin loaded microbubbles after ultrasound exposure.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):e113-4.
2010: Kevin Braeckmans; Kevin Buyens; Broes Naeye; Dries Vercauteren; Hendrik Deschout; Koen Raemdonck; Katrien Remaut; Niek N Sanders; Jo Demeester; Stefaan C De Smedt
Advanced fluorescence microscopy methods illuminate the transfection pathway of nucleic acid nanoparticles.
Journal of controlled release : official journal of the Controlled Release Society 2010;148(1):69-74.
2010: Kevin Braeckmans; Kevin Buyens; Wim Bouquet; Chris Vervaet; Philippe Joye; Filip De Vos; Laurent Plawinski; Loïc Doeuvre; Eduardo Angles-Cano; Niek N Sanders; Jo Demeester; Stefaan C De Smedt
Sizing nanomatter in biological fluids by fluorescence single particle tracking.
Nano letters 2010;10(11):4435-42.
2010: Koen Raemdonck; B Naeye; A Høgset; Jo Demeester; Stefaan C De Smedt
Prolonged gene silencing by combining siRNA nanogels and photochemical internalization.
Journal of controlled release : official journal of the Controlled Release Society 2010;145(3):281-8.
2010: B Naeye; Koen Raemdonck; Katrien Remaut; B Sproat; Jo Demeester; Stefaan C De Smedt
PEGylation of biodegradable dextran nanogels for siRNA delivery.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;40(4):342-51.
2010: Chaobo Huang; Bart Lucas; Chris Vervaet; Kevin Braeckmans; Serge Van Calenbergh; Izet Karalic; Mado Vandewoestyne; Dieter Deforce; Jo Demeester; Stefaan C De Smedt
Unbreakable codes in electrospun fibers: digitally encoded polymers to stop medicine counterfeiting.
Advanced materials (Deerfield Beach, Fla.) 2010;22(24):2657-62.
2010: Katrien Remaut; N Symens; Bart Lucas; Jo Demeester; Stefaan C De Smedt
Efficient delivery of intact phosphodiester oligonucleotides by poly-beta-amino esters.
Journal of controlled release : official journal of the Controlled Release Society 2010;144(1):65-74.
2010: Dries Vercauteren; Roosmarijn Vandenbroucke; Arwyn T Jones; Joanna Rejman; Jo Demeester; Stefaan C De Smedt; Niek N Sanders; Kevin Braeckmans
The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(3):561-9.
2010: Mathieu Vinken; Elke Decrock; Elke De Vuyst; Marijke De Bock; Roosmarijn E Vandenbroucke; Bruno G De Geest; Jo Demeester; Niek N Sanders; Tamara Vanhaecke; Luc Leybaert; Vera Rogiers
Connexin32 hemichannels contribute to the apoptotic-to-necrotic transition during Fas-mediated hepatocyte cell death.
Cellular and molecular life sciences : CMLS 2010;67(6):907-18.
2010: Joanna Rejman; Ida De Fino; Moira Paroni; Alessandra Bragonzi; Jo Demeester; Stefaan De Smedt; Massimo Conese
Impact of chronic pulmonary infection with Pseudomonas aeruginosa on transfection mediated by viral and nonviral vectors.
Human gene therapy 2010;21(3):351-6.
2010: Kevin Buyens; Martin Meyer; Ernst Wagner; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy.
Journal of controlled release : official journal of the Controlled Release Society 2010;141(1):38-41.
2010: Stefaan De Koker; Thomas Naessens; Bruno G De Geest; Pieter Bogaert; Jo Demeester; Stefaan C De Smedt; Johan Grooten
Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(1):203-11.
2010: Ine Lentacker; Bart Geers; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Design and evaluation of doxorubicin-containing microbubbles for ultrasound-triggered doxorubicin delivery: cytotoxicity and mechanisms involved.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(1):101-8.
2009: Kevin Buyens; Jo Demeester; Stefaan S De Smedt; Niek N Sanders
Elucidating the encapsulation of short interfering RNA in PEGylated cationic liposomes.
Langmuir : the ACS journal of surfaces and colloids 2009;25(9):4886-91.
2009: Bruno G De Geest; Stefaan De Koker; Jo Demeester; Stefaan C De Smedt; Wim E Hennink
Pulsed in vitro release and in vivo behavior of exploding microcapsules.
Journal of controlled release : official journal of the Controlled Release Society 2009;135(3):268-73.
2009: Ine Lentacker; Nan Wang; Roosmarijn Vandenbroucke; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Ultrasound exposure of lipoplex loaded microbubbles facilitates direct cytoplasmic entry of the lipoplexes.
Molecular pharmaceutics 2009;6(2):457-67.
2009: Justin Hanes; Jo Demeester
Drug and gene delivery to mucosal tissues: the mucus barrier. Preface.
Advanced drug delivery reviews 2009;61(2):73-4.
2009: Niek N Sanders; Carsten Rudolph; Kevin Braeckmans; Stefaan C De Smedt; Jo Demeester
Extracellular barriers in respiratory gene therapy.
Advanced drug delivery reviews 2009;61(2):115-27.
2009: Stefaan De Koker; Bruno G De Geest; Satwinder K Singh; Riet De Rycke; Thomas Naessens; Yvette van Kooyk; Jo Demeester; Stefaan C De Smedt; Johan Grooten
Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross-presentation of encapsulated antigens.
Angewandte Chemie (International ed. in English) 2009;48(45):8485-9.
2008: Ine Lentacker; Roosmarijn Vandenbroucke; Bart Lucas; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
New strategies for nucleic acid delivery to conquer cellular and nuclear membranes.
Journal of controlled release : official journal of the Controlled Release Society 2008;132(3):279-88.
2008: Bruno G De Geest; Mike McShane; Jo Demeester; Stefaan C De Smedt; Wim E Hennink
Microcapsules ejecting nanosized species into the environment.
Journal of the American Chemical Society 2008;130(44):14480-2.
2008: Liesbeth Peeters; Ine Lentacker; Roosmarijn Vandenbroucke; Bart Lucas; Jo Demeester; Niek N Sanders; Stefaan C De Smedt
Can ultrasound solve the transport barrier of the neural retina?
Pharmaceutical research 2008;25(11):2657-65.
2008: Koen Raemdonck; Roosmarijn Vandenbroucke; Jo Demeester; Niek N Sanders; Stefaan C De Smedt
Maintaining the silence: reflections on long-term RNAi.
Drug discovery today 2008;13(21-22):917-31.
2008: Davide Mazza; Kevin Braeckmans; Francesca Cella; Ilaria Testa; Dries Vercauteren; Jo Demeester; Stefaan S De Smedt; Alberto Diaspro
A new FRAP/FRAPa method for three-dimensional diffusion measurements based on multiphoton excitation microscopy.
Biophysical journal 2008;95(7):3457-69.
2008: S Derveaux; Barbara G Stubbe; Kevin Braeckmans; Chris Roelant; K Sato; Jo Demeester; Stefaan C De Smedt
Synergism between particle-based multiplexing and microfluidics technologies may bring diagnostics closer to the patient.
Analytical and bioanalytical chemistry 2008;391(7):2453-67.
2008: Roosmarijn Vandenbroucke; Bruno G De Geest; Stefan Bonné; Mathieu Vinken; Tamara Van Haecke; Harry Heimberg; Ernst Wagner; Vera Rogiers; Stefaan C De Smedt; Jo Demeester; Niek N Sanders
Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters).
The journal of gene medicine 2008;10(7):783-94.
2008: Roosmarijn Vandenbroucke; Ine Lentacker; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles.
Journal of controlled release : official journal of the Controlled Release Society 2008;126(3):265-73.
2008: Tinneke Van Thienen; Jo Demeester; Stefaan C De Smedt
Screening poly(ethyleneglycol) micro- and nanogels for drug delivery purposes.
International journal of pharmaceutics 2008;351(1-2):174-85.
2008: Bruno G De Geest; Wim Van Camp; Filip E Du Prez; Stefaan C De Smedt; Jo Demeester; Wim E Hennink
Biodegradable microcapsules designed via 'click' chemistry.
Chemical communications (Cambridge, England) 2008;(2):190-2.
2008: Stefaan Derveaux; Barbara G Stubbe; Chris Roelant; Marc Leblans; Bruno G De Geest; Jo Demeester; Stefaan C De Smedt
Layer-by-layer coated digitally encoded microcarriers for quantification of proteins in serum and plasma.
Analytical chemistry 2008;80(1):85-94.
2007: Niek N Sanders; Liesbeth Peeters; Ine Lentacker; Jo Demeester; Stefaan C De Smedt
Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer.
Journal of controlled release : official journal of the Controlled Release Society 2007;122(3):226-35.
2007: Stefaan Derveaux; Bruno G De Geest; Chris Roelant; Kevin Braeckmans; Jo Demeester; Stefaan C De Smedt
Multifunctional layer-by-layer coating of digitally encoded microparticles.
Langmuir : the ACS journal of surfaces and colloids 2007;23(20):10272-9.
2007: Tinneke Van Thienen; Koen Raemdonck; Jo Demeester; Stefaan C De Smedt
Protein release from biodegradable dextran nanogels.
Langmuir : the ACS journal of surfaces and colloids 2007;23(19):9794-801.
2007: Liesbeth Peeters; Niek N Sanders; A Jones; Jo Demeester; Stefaan C De Smedt
Post-pegylated lipoplexes are promising vehicles for gene delivery in RPE cells.
Journal of controlled release : official journal of the Controlled Release Society 2007;121(3):208-17.
2007: Katrien Remaut; Bart Lucas; Koen Raemdonck; Kevin Braeckmans; Jo Demeester; Stefaan C De Smedt
Can we better understand the intracellular behavior of DNA nanoparticles by fluorescence correlation spectroscopy?
Journal of controlled release : official journal of the Controlled Release Society 2007;121(1-2):49-63.
2007: Tinneke Van Thienen; Ferenc Horkay; Kevin Braeckmans; Barbara G Stubbe; Jo Demeester; Stefaan C De Smedt
Influence of free chains on the swelling pressure of PEG-HEMA and dex-HEMA hydrogels.
International journal of pharmaceutics 2007;337(1-2):31-9.
2007: Niek N Sanders; Vincent G H Eijsink; Petra S van den Pangaart; R J Joost van Neerven; Peter J Simons; Stefaan C De Smedt; Jo Demeester
Mucolytic activity of bacterial and human chitinases.
Biochimica et biophysica acta 2007;1770(5):839-46.
2007: Bruno G De Geest; Niek N Sanders; Gleb B Sukhorukov; Jo Demeester; Stefaan C De Smedt
Release mechanisms for polyelectrolyte capsules.
Chemical Society reviews 2007;36(4):636-49.
2007: Katrien Remaut; Bart Lucas; Koen Raemdonck; Kevin Braeckmans; Jo Demeester; Stefaan C De Smedt
Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine.
Biomacromolecules 2007;8(4):1333-40.
2007: Kevin Braeckmans; Katrien Remaut; Roosmarijn Vandenbroucke; Bart Lucas; Stefaan C De Smedt; Jo Demeester
Line FRAP with the confocal laser scanning microscope for diffusion measurements in small regions of 3-D samples.
Biophysical journal 2007;92(6):2172-83.
2007: Roosmarijn Vandenbroucke; Stefaan C De Smedt; Jo Demeester; Niek N Sanders
Cellular entry pathway and gene transfer capacity of TAT-modified lipoplexes.
Biochimica et biophysica acta 2007;1768(3):571-9.
2007: Katrien Remaut; Bart Lucas; Kevin Braeckmans; Jo Demeester; Stefaan C De Smedt
Pegylation of liposomes favours the endosomal degradation of the delivered phosphodiester oligonucleotides.
Journal of controlled release : official journal of the Controlled Release Society 2007;117(2):256-66.
2007: Liesbeth Peeters; Niek N Sanders; Jo Demeester; Stefaan C De Smedt
Challenges in non-viral ocular gene transfer.
Biochemical Society transactions 2007;35(Pt 1):47-9.
2007: Roosmarijn Vandenbroucke; Bart Lucas; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Nuclear accumulation of plasmid DNA can be enhanced by non-selective gating of the nuclear pore.
Nucleic acids research 2007;35(12):e86.
2006: Ine Lentacker; Stefaan C De Smedt; Jo Demeester; Niek N Sanders
Microbubbles which bind and protect DNA against nucleases.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e73-5.
2006: Tinneke Van Thienen; Bart Lucas; Jo Demeester; Stefaan C De Smedt
On the synthesis and characterization of biodegradable dextran nanogels with tunable degradation properties.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):e12-3.
2006: Bruno G De Geest; Christophe Déjugnat; E Verhoeven; Gleb B Sukhorukov; Alain M Jonas; Jérôme Plain; Jo Demeester; Stefaan C De Smedt
Layer-by-layer coating of degradable microgels for pulsed drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):159-69.
2006: Niek N Sanders; Hilde Franckx; Kris De Boeck; J Haustraete; Stefaan C De Smedt; Jo Demeester
Role of magnesium in the failure of rhDNase therapy in patients with cystic fibrosis.
Thorax 2006;61(11):962-8.
2006: Katrien Remaut; Niek N Sanders; Farzaneh Fayazpour; Jo Demeester; Stefaan C De Smedt
Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes.
Journal of controlled release : official journal of the Controlled Release Society 2006;115(3):335-43.
2006: Farzaneh Fayazpour; Bart Lucas; Carmen Alvarez-Lorenzo; Niek N Sanders; Jo Demeester; Stefaan C De Smedt
Physicochemical and transfection properties of cationic Hydroxyethylcellulose/DNA nanoparticles.
Biomacromolecules 2006;7(10):2856-62.
2006: Koen Raemdonck; Katrien Remaut; Bart Lucas; Niek N Sanders; Jo Demeester; Stefaan C De Smedt
In situ analysis of single-stranded and duplex siRNA integrity in living cells.
Biochemistry 2006;45(35):10614-23.
2006: Ine Lentacker; Bruno G De Geest; Roosmarijn Vandenbroucke; Liesbeth Peeters; Jo Demeester; Stefaan C De Smedt; Niek N Sanders
Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA.
Langmuir : the ACS journal of surfaces and colloids 2006;22(17):7273-8.
2006: Kevin Braeckmans; Barbara G Stubbe; Katrien Remaut; Jo Demeester; Stefaan C De Smedt
Anomalous photobleaching in fluorescence recovery after photobleaching measurements due to excitation saturation--a case study for fluorescein.
Journal of biomedical optics 2006;11(4):044013.
2006: Bruno G De Geest; Els Mehuys; Gert Laekeman; Jo Demeester; Stefaan C De Smedt
Pulsed drug delivery.
Expert opinion on drug delivery 2006;3(4):459-62.
2006: Felipe Alvarez-Manceñido; Kevin Braeckmans; Stefaan C De Smedt; Jo Demeester; Mariana Landin; Ramón Martínez-Pacheco
Characterization of diffusion of macromolecules in konjac glucomannan solutions and gels by fluorescence recovery after photobleaching technique.
International journal of pharmaceutics 2006;316(1-2):37-46.
2006: Bruno G De Geest; Alain M Jonas; Jo Demeester; Stefaan C De Smedt
Glucose-responsive polyelectrolyte capsules.
Langmuir : the ACS journal of surfaces and colloids 2006;22(11):5070-4.
2006: W L J Hinrichs; F A Manceñido; Niek N Sanders; Kevin Braeckmans; Stefaan C De Smedt; Jo Demeester; Henderik W Frijlink
The choice of a suitable oligosaccharide to prevent aggregation of PEGylated nanoparticles during freeze thawing and freeze drying.
International journal of pharmaceutics 2006;311(1-2):237-44.
2006: Katrien Remaut; Bart Lucas; Kevin Braeckmans; Niek N Sanders; Jo Demeester; Stefaan C De Smedt
Delivery of phosphodiester oligonucleotides: can DOTAP/DOPE liposomes do the trick?
Biochemistry 2006;45(6):1755-64.
2006: Bruno G De Geest; Barbara G Stubbe; Alain M Jonas; Tinneke Van Thienen; W L J Hinrichs; Jo Demeester; Stefaan C De Smedt
Self-exploding lipid-coated microgels.
Biomacromolecules 2006;7(1):373-9.
2005: Katrien Remaut; Bart Lucas; Kevin Braeckmans; Niek N Sanders; Jo Demeester; Stefaan C De Smedt
Protection of oligonucleotides against nucleases by pegylated and non-pegylated liposomes as studied by fluorescence correlation spectroscopy.
Journal of controlled release : official journal of the Controlled Release Society 2005;110(1):212-26.
2005: Bruno G De Geest; John Paul Urbanski; Todd Thorsen; Jo Demeester; Stefaan C De Smedt
Synthesis of monodisperse biodegradable microgels in microfluidic devices.
Langmuir : the ACS journal of surfaces and colloids 2005;21(23):10275-9.
2005: Liesbeth Peeters; Niek N Sanders; Kevin Braeckmans; Koen Boussery; Johan Van de Voorde; Stefaan C De Smedt; Jo Demeester
Vitreous: a barrier to nonviral ocular gene therapy.
Investigative ophthalmology & visual science 2005;46(10):3553-61.
2005: Bart Lucas; Katrien Remaut; Niek N Sanders; Kevin Braeckmans; Stefaan C De Smedt; Jo Demeester
Studying the intracellular dissociation of polymer-oligonucleotide complexes by dual color fluorescence fluctuation spectroscopy and confocal imaging.
Biochemistry 2005;44(29):9905-12.
2005: W L J Hinrichs; Niek N Sanders; Stefaan C De Smedt; Jo Demeester; Henderik W Frijlink
Inulin is a promising cryo- and lyoprotectant for PEGylated lipoplexes.
Journal of controlled release : official journal of the Controlled Release Society 2005;103(2):465-79.
2005: Bart Lucas; Katrien Remaut; Niek N Sanders; Kevin Braeckmans; Stefaan C De Smedt; Jo Demeester
Towards a better understanding of the dissociation behavior of liposome-oligonucleotide complexes in the cytosol of cells.
Journal of controlled release : official journal of the Controlled Release Society 2005;103(2):435-50.
2005: Katrien Remaut; Bart Lucas; Kevin Braeckmans; Niek N Sanders; Stefaan C De Smedt; Jo Demeester
FRET-FCS as a tool to evaluate the stability of oligonucleotide drugs after intracellular delivery.
Journal of controlled release : official journal of the Controlled Release Society 2005;103(1):259-71.
2005: Bart Lucas; Katrien Remaut; Stefaan C De Smedt; Jo Demeester
Studies on the intracellular release of genetic drugs from pharmaceutical carriers.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):402-5.
2005: Katrien Remaut; Bart Lucas; Kevin Braeckmans; Niek N Sanders; Stefaan C De Smedt; Jo Demeester
Fluorescence energy transfer to study the degradation of double-labeled oligonucleotides.
Journal of controlled release : official journal of the Controlled Release Society 2005;101(1-3):352-4.
2005: Stefaan C De Smedt; Katrien Remaut; Bart Lucas; Kevin Braeckmans; Niek N Sanders; Jo Demeester
Studying biophysical barriers to DNA delivery by advanced light microscopy.
Advanced drug delivery reviews 2005;57(1):191-210.
2004: Barbara G Stubbe; Stefaan C De Smedt; Jo Demeester
"Programmed polymeric devices" for pulsed drug delivery.
Pharmaceutical research 2004;21(10):1732-40.
2004: Bart Lucas; Elsa Van Rompaey; Katrien Remaut; Niek N Sanders; Stefaan C De Smedt; Jo Demeester
On the biological activity of anti-ICAM-1 oligonucleotides complexed to non-viral carriers.
Journal of controlled release : official journal of the Controlled Release Society 2004;96(1):207-19.
2003: Kevin Braeckmans; Liesbeth Peeters; Niek N Sanders; Stefaan C De Smedt; Jo Demeester
Three-dimensional fluorescence recovery after photobleaching with the confocal scanning laser microscope.
Biophysical journal 2003;85(4):2240-52.
2003: Barbara G Stubbe; Ferenc Horkay; Brian Amsden; Wim E Hennink; Stefaan C De Smedt; Jo Demeester
Tailoring the swelling pressure of degrading dextran hydroxyethyl methacrylate hydrogels.
Biomacromolecules 2003;4(3):691-5.
2003: Kevin Braeckmans; Stefaan C De Smedt; Chris Roelant; Marc Leblans; Rudi Pauwels; Jo Demeester
Encoding microcarriers by spatial selective photobleaching.
Nature materials 2003;2(3):169-73.
2003: Niek N Sanders; Stefaan C De Smedt; Jo Demeester
Mobility and stability of gene complexes in biogels.
Journal of controlled release : official journal of the Controlled Release Society 2003;87(1-3):117-29.
2002: Tom K L Meyvis; Barbara G Stubbe; Mies J van Steenbergen; Wim E Hennink; Stefaan C De Smedt; Jo Demeester
A comparison between the use of dynamic mechanical analysis and oscillatory shear rheometry for the characterisation of hydrogels.
International journal of pharmaceutics 2002;244(1-2):163-8.
2002: Geert J Vergote; Chris Vervaet; I Van Driessche; S Hoste; Stefaan C De Smedt; Jo Demeester; R A Jain; S Ruddy; Jean Paul Remon
In vivo evaluation of matrix pellets containing nanocrystalline ketoprofen.
International journal of pharmaceutics 2002;240(1-2):79-84.
2002: Kevin Braeckmans; Stefaan C De Smedt; Marc Leblans; Rudi Pauwels; Jo Demeester
Encoding microcarriers: present and future technologies.
Nature reviews. Drug discovery 2002;1(6):447-56.
2002: Niek N Sanders; Elsa Van Rompaey; Stefaan C De Smedt; Jo Demeester
On the transport of lipoplexes through cystic fibrosis sputum.
Pharmaceutical research 2002;19(4):451-6.
2002: Niek N Sanders; Stefaan C De Smedt; Seng Cheng; Jo Demeester
Pegylated GL67 lipoplexes retain their gene transfection activity after exposure to components of CF mucus.
Gene therapy 2002;9(6):363-71.
2001: Tom K L Meyvis; Stefaan C De Smedt; Barbara G Stubbe; Wim E Hennink; Jo Demeester
On the release of proteins from degrading dextran methacrylate hydrogels and the correlation with the rheologic properties of the hydrogels.
Pharmaceutical research 2001;18(11):1593-9.
2001: Niek N Sanders; Elsa Van Rompaey; Stefaan C De Smedt; Jo Demeester
Structural alterations of gene complexes by cystic fibrosis sputum.
American journal of respiratory and critical care medicine 2001;164(3):486-93.
2001: Barbara G Stubbe; B Maris; Guy Van den Mooter; Stefaan C De Smedt; Jo Demeester
The in vitro evaluation of 'azo containing polysaccharide gels' for colon delivery.
Journal of controlled release : official journal of the Controlled Release Society 2001;75(1-2):103-14.
2001: Elsa Van Rompaey; Yves Engelborghs; Niek N Sanders; Stefaan C De Smedt; Jo Demeester
Interactions between oligonucleotides and cationic polymers investigated by fluorescence correlation spectroscopy.
Pharmaceutical research 2001;18(7):928-36.
2001: Geert J Vergote; Chris Vervaet; I Van Driessche; S Hoste; Stefaan C De Smedt; Jo Demeester; R A Jain; S Ruddy; Jean Paul Remon
An oral controlled release matrix pellet formulation containing nanocrystalline ketoprofen.
International journal of pharmaceutics 2001;219(1-2):81-7.
2001: SJ de Jong; Stefaan C De Smedt; Jo Demeester; Cornelus F van Nostrum; J Jantina Kettenes-van den Bosch; Wim E Hennink
Biodegradable hydrogels based on stereocomplex formation between lactic acid oligomers grafted to dextran.
Journal of controlled release : official journal of the Controlled Release Society 2001;72(1-3):47-56.
2001: Elsa Van Rompaey; Y Chen; J D Müller; E Gratton; E Van Craenenbroeck; Yves Engelborghs; Stefaan C De Smedt; Jo Demeester
Fluorescence fluctuation analysis for the study of interactions between oligonucleotides and polycationic polymers.
Biological chemistry 2001;382(3):379-86.
2000: Niek N Sanders; Stefaan C De Smedt; Elsa Van Rompaey; P Simoens; Frans De Baets; Jo Demeester
Cystic fibrosis sputum: a barrier to the transport of nanospheres.
American journal of respiratory and critical care medicine 2000;162(5):1905-11.
2000: Dieter Ameye; Jody Voorspoels; Jean Paul Remon; Jo Demeester; Stefaan C De Smedt
Optimisation of an in vitro procedure for the determination of the enzymatic inhibition potency of multifunctional polymers.
Journal of controlled release : official journal of the Controlled Release Society 2000;68(3):413-7.
2000: N N Sanders; Stefaan C De Smedt; Jo Demeester
The physical properties of biogels and their permeability for macromolecular drugs and colloidal drug carriers.
Journal of pharmaceutical sciences 2000;89(7):835-49.
2000: Stefaan C De Smedt; Jo Demeester; Wim E Hennink
Cationic polymer based gene delivery systems.
Pharmaceutical research 2000;17(2):113-26.
2000: Robert Stenekes; Stefaan C De Smedt; Jo Demeester; G Sun; Zhibing Zhang; Wim E Hennink
Pore sizes in hydrated dextran microspheres.
Biomacromolecules 2000;1(4):696-703.
1999: Stefaan C De Smedt; Tom K L Meyvis; Patrick Van Oostveldt; Jo Demeester
A new microphotolysis based approach for mapping the mobility of drugs in microscopic drug delivery devices.
Pharmaceutical research 1999;16(10):1639-42.
1999: Tom K L Meyvis; Stefaan C De Smedt; Patrick Van Oostveldt; Jo Demeester
Fluorescence recovery after photobleaching: a versatile tool for mobility and interaction measurements in pharmaceutical research.
Pharmaceutical research 1999;16(8):1153-62.
1998: Mireille N Vankemmelbeke; P M Dekeyser; Anthony P Hollander; David J Buttle; Jo Demeester
Characterization of helical cleavages in type II collagen generated by matrixins.
The Biochemical journal 1998;330 ( Pt 2)():633-40.
1996: K Haussner; P Hilgendorf; C Hofbauer; Jo Demeester; A Lauwers
New international F.I.P. method for the determination of the activity of Aspergillus oryzae proteases.
Die Pharmazie 1996;51(12):946-50.
1995: K P Vercruysse; A R Lauwers; Jo Demeester
Kinetic investigation of the action of hyaluronidase on hyaluronan using the Morgan-Elson and neocuproine assays.
The Biochemical journal 1995;310 ( Pt 1)():55-9.
1995: P M Dekeyser; David J Buttle; Bart Devreese; J Van Beeumen; Jo Demeester; A Lauwers
Kinetic constants for the hydrolysis of aggrecan by the papaya proteinases and their relevance for chemonucleolysis.
Archives of biochemistry and biophysics 1995;320(2):375-9.
1995: K P Vercruysse; A R Lauwers; Jo Demeester
Absolute and empirical determination of the enzymatic activity and kinetic investigation of the action of hyaluronidase on hyaluronan using viscosimetry.
The Biochemical journal 1995;306 ( Pt 1)():153-60.
1994: P Arzoglou; C Goudoula; P Tsantili; Jean-Marc Lessinger; Georges Férard; V Mignot; N Samyn; Jo Demeester; A Lauwers; H Brettschneider
Transferability of lipase titrimetric assays: deductions from an interlaboratory study.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1994;32(10):773-7.
1994: P M Dekeyser; Stefaan C De Smedt; Jo Demeester; A Lauwers
Fractionation and purification of the thiol proteinases from papaya latex.
Journal of chromatography. B, Biomedical applications 1994;656(1):203-8.
1994: K P Vercruysse; A R Lauwers; Jo Demeester
Kinetic investigation of the degradation of hyaluronan by hyaluronidase using gel permeation chromatography.
Journal of chromatography. B, Biomedical applications 1994;656(1):179-90.
1993: G M Vandenbossche; P Van Oostveldt; Jo Demeester; J P Remon
The molecular weight cut-off of microcapsules is determined by the reaction between alginate and polylysine.
Biotechnology and bioengineering 1993;42(3):381-6.
1993: Stefaan C De Smedt; P Dekeyser; V Ribitsch; A Lauwers; Jo Demeester
Viscoelastic and transient network properties of hyaluronic acid as a function of the concentration.
Biorheology 1993;30(1):31-41.
1978: Jo Demeester; M Bracke; R Vochten; A Lauwers
Differential spectrophotometric determination of tyrosine and tryptophan in pharmaceutical amino acid solutions.
Journal of pharmaceutical sciences 1978;67(5):729-30.
1978: Jo Demeester; H Steyaert; M Bracke; A Lauwers
Light-scattering studies on the action of endocellulases [proceedings].
Biochemical Society transactions 1978;6(1):227-8.
1977: Jo Demeester; W Cooreman; M Bracke; A Lauwers
Determination of endocellulase activity by viscosimetry [proceedings].
Biochemical Society transactions 1977;5(4):1115-7.
1976: W M Cooreman; S Scharpé; Jo Demeester; A Lauwers
Bromelain, biochemical and pharmacological properties.
Pharmaceutica acta Helvetiae 1976;51(4):73-97.