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Leonardo Carvalho

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Yuri Martins; Peng Kai Ong; Pamela Orjuela-Sánchez; Graziela M Zanini; Leah Clemmer; John A Frangos; Leonardo J M Carvalho
Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria.
Graziela M Zanini; Pedro Cabrales; John A Frangos; Yuri Martins; Leonardo J M Carvalho
S-nitrosoglutathione prevents experimental cerebral malaria.
Pamela Orjuela-Sánchez; Erika Duggan; John A Frangos; John Nolan; Leonardo J M Carvalho
A lactate dehydrogenase ELISA-based assay for the in vitro determination of Plasmodium berghei sensitivity to anti-malarial drugs.

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2013: Yuri Martins; Peng Kai Ong; Pamela Orjuela-Sánchez; Graziela M Zanini; Leah Clemmer; John A Frangos; Leonardo J M Carvalho
Slow and continuous delivery of a low dose of nimodipine improves survival and electrocardiogram parameters in rescue therapy of mice with experimental cerebral malaria.
Malaria journal 2013;12():138.
2012: Graziela M Zanini; Pedro Cabrales; John A Frangos; Yuri Martins; Leonardo J M Carvalho
S-nitrosoglutathione prevents experimental cerebral malaria.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2012;7(2):477-87.
2012: Pamela Orjuela-Sánchez; Erika Duggan; John A Frangos; John Nolan; Leonardo J M Carvalho
A lactate dehydrogenase ELISA-based assay for the in vitro determination of Plasmodium berghei sensitivity to anti-malarial drugs.
Malaria journal 2012;11():366.
2012: Yuri Martins; Graziela M Zanini; John A Frangos; Leonardo J M Carvalho
Efficacy of different nitric oxide-based strategies in preventing experimental cerebral malaria by Plasmodium berghei ANKA.
PloS one 2012;7(2):e32048.
2011: Lilian R Pratt-Riccio; Evelyn Kety Pratt Riccio; Luciene Aquino Silva; Michael Theisen; Paulo Renato Rivas Totino; Cesare Bianco; Surza L G Rocha; Joseli De Oliveira-Ferreira; Leonardo J M Carvalho; Cláudio Tadeu Daniel-Ribeiro; Fabrício Dias-Da-Silva; Vítor Ennes-Vidal; Maria de Fátima Ferreira-da-Cruz; Ana G C Neves-Ferreira; Jonas Perales; Daiana De Souza Perce-Da-Silva; Dalma M Banic
Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth.
Memórias do Instituto Oswaldo Cruz 2011;106 Suppl 1():34-43.
2011: Pedro Cabrales; Graziela M Zanini; Diana Meays; John A Frangos; Leonardo J M Carvalho
Nitric oxide protection against murine cerebral malaria is associated with improved cerebral microcirculatory physiology.
The Journal of infectious diseases 2011;203(10):1454-63.
2011: Massimo Bertinaria; Stefano Guglielmo; Barbara Rolando; Marta Giorgis; Cristina Aragno; Roberta Fruttero; Alberto Gasco; Silvia Parapini; Donatella Taramelli; Yuri Martins; Leonardo J M Carvalho
Amodiaquine analogues containing NO-donor substructures: synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria.
European journal of medicinal chemistry 2011;46(5):1757-67.
2011: L Clemmer; Yuri Martins; G M Zanini; John A Frangos; Leonardo J M Carvalho
Artemether and artesunate show the highest efficacies in rescuing mice with late-stage cerebral malaria and rapidly decrease leukocyte accumulation in the brain.
Antimicrobial agents and chemotherapy 2011;55(4):1383-90.
2011: Graziela M Zanini; John A Frangos; Wisam Barkho; Pedro Cabrales; Leonardo J M Carvalho
Exogenous nitric oxide decreases brain vascular inflammation, leakage and venular resistance during Plasmodium berghei ANKA infection in mice.
Journal of neuroinflammation 2011;8():66.
2010: Leonardo J M Carvalho
Murine cerebral malaria: how far from human cerebral malaria?
Trends in parasitology 2010;26(6):271-2.
2010: Pedro Cabrales; Graziela M Zanini; Diana Meays; John A Frangos; Leonardo J M Carvalho
Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine.
The American journal of pathology 2010;176(3):1306-15.
2010: Pedro Cabrales; Leonardo J M Carvalho
Intravital microscopy of the mouse brain microcirculation using a closed cranial window.
Journal of visualized experiments : JoVE 2010;(45):.
2010: Yuri Martins; Guilherme L Werneck; Leonardo J M Carvalho; Beatriz P T Silva; Bruno G Andrade; Tadeu M Souza; Diogo O Souza; Cláudio Tadeu Daniel-Ribeiro
Algorithms to predict cerebral malaria in murine models using the SHIRPA protocol.
Malaria journal 2010;9():85.
2009: Yuri Martins; Mary Jane Smith; Marcelo Pelajo-Machado; Guilherme Loureiro Werneck; Henrique Leonel Lenzi; Cláudio Tadeu Daniel-Ribeiro; Leonardo J M Carvalho
Characterization of cerebral malaria in the outbred Swiss Webster mouse infected by Plasmodium berghei ANKA.
International journal of experimental pathology 2009;90(2):119-30.
2009: C R de Souza; F J Aragão; E C O Moreira; C N M Costa; S B Nascimento; Leonardo J M Carvalho
Isolation and characterization of the promoter sequence of a cassava gene coding for Pt2L4, a glutamic acid-rich protein differentially expressed in storage roots.
Genetics and molecular research : GMR 2009;8(1):334-44.
2009: Yuri Martins; Leonardo J M Carvalho; Cláudio Tadeu Daniel-Ribeiro
Challenges in the determination of early predictors of cerebral malaria: lessons from the human disease and the experimental murine models.
Neuroimmunomodulation 2009;16(2):134-45.
2008: Andréa Aparecida Morais Fernandes; Leonardo J M Carvalho; Graziela Maria Zanini; Ana Maria Revorêdo da Silva Ventura; José Maria Souza; Paulo Marcelo Cotias; Isaac Lima Silva-Filho; Cláudio Tadeu Daniel-Ribeiro
Similar cytokine responses and degrees of anemia in patients with Plasmodium falciparum and Plasmodium vivax infections in the Brazilian Amazon region.
Clinical and vaccine immunology : CVI 2008;15(4):650-8.
2007: Leonardo J M Carvalho; Maria F Ferreira-da-cruz; Cláudio Tadeu Daniel-Ribeiro; Marcelo Pelajo-Machado; Henrique Leonel Lenzi
Germinal center architecture disturbance during Plasmodium berghei ANKA infection in CBA mice.
Malaria journal 2007;6():59.
2006: Leonardo J M Carvalho; Maria F Ferreira-da-cruz; Cláudio Tadeu Daniel-Ribeiro; Marcelo Pelajo-Machado; Henrique Leonel Lenzi
Plasmodium berghei ANKA infection induces thymocyte apoptosis and thymocyte depletion in CBA mice.
Memórias do Instituto Oswaldo Cruz 2006;101(5):523-8.
2006: Rosana M F Libonati; Maristela G Cunha; José M Souza; Marcos V N Santos; Salma G Oliveira; Cláudio Tadeu Daniel-Ribeiro; Leonardo J M Carvalho; José L M do Nascimento
Estradiol, but not dehydroepiandrosterone, decreases parasitemia and increases the incidence of cerebral malaria and the mortality in plasmodium berghei ANKA-infected CBA mice.
Neuroimmunomodulation 2006;13(1):28-35.
2005: Lilian R Pratt-Riccio; Josué C Lima-Junior; Leonardo J M Carvalho; Michael Theisen; Erika C Espíndola-Mendes; Fátima Santos; Joseli Oliveira-Ferreira; Anna Carla Goldberg; Cláudio Tadeu Daniel-Ribeiro; Dalma M Banic
Antibody response profiles induced by Plasmodium falciparum glutamate-rich protein in naturally exposed individuals from a Brazilian area endemic for malaria.
The American journal of tropical medicine and hygiene 2005;73(6):1096-103.
2005: Leonardo J M Carvalho; Francisco Acácio Alves; Cesare Bianco; Salma G Oliveira; Graziela M Zanini; Soe Soe; Pierre Druilhe; Michael Theisen; J A P C Muniz; Cláudio Tadeu Daniel-Ribeiro
Immunization of Saimiri sciureus monkeys with a recombinant hybrid protein derived from the Plasmodium falciparum antigen glutamate-rich protein and merozoite surface protein 3 can induce partial protection with Freund and Montanide ISA720 adjuvants.
Clinical and diagnostic laboratory immunology 2005;12(2):242-8.
2004: Leonardo J M Carvalho; Salma G Oliveira; Michael Theisen; Francisco Acácio Alves; M C R Andrade; Graziela M Zanini; M C O Brígido; Claude Oeuvray; Marinete Marins Póvoa; J A P C Muniz; Pierre Druilhe; Cláudio Tadeu Daniel-Ribeiro
Immunization of Saimiri sciureus monkeys with Plasmodium falciparum merozoite surface protein-3 and glutamate-rich protein suggests that protection is related to antibody levels.
Scandinavian journal of immunology 2004;59(4):363-72.
2002: Leonardo J M Carvalho; Cláudio Tadeu Daniel-Ribeiro; H Goto
Malaria vaccine: candidate antigens, mechanisms, constraints and prospects.
Scandinavian journal of immunology 2002;56(4):327-43.
2000: Leonardo J M Carvalho; Henrique Leonel Lenzi; Marcelo Pelajo-Machado; DN Oliveira; Cláudio Tadeu Daniel-Ribeiro; Maria F Ferreira-da-cruz
Plasmodium berghei: cerebral malaria in CBA mice is not clearly related to plasma TNF levels or intensity of histopathological changes.
Experimental parasitology 2000;95(1):1-7.
2000: Leonardo J M Carvalho; Salma G Oliveira; Francisco Acácio Alves; M C O Brígido; J A P C Muniz; Cláudio Tadeu Daniel-Ribeiro
Aotus infulatus monkey is susceptible to Plasmodium falciparum infection and may constitute an alternative experimental model for malaria.
Memórias do Instituto Oswaldo Cruz 2000;95(3):363-5.