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Ted Dawson

Research Profile

Anatomy

Disorders

Parkinson's Disease

Living Beings

Chemicals & Drugs

Physiology

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M Scott Vandiver; Risheng Xu; Han Seok Ko; Yun Il Lee; Ted M Dawson; Valina Dawson; Senthilkumar Karuppagounder; Bindu D Paul; Feng Rao; Nilkantha Sen; Adele M Snowman; Solomon H Snyder
Sulfhydration mediates neuroprotective actions of parkin.
Paolo Calabresi; Valina Dawson; Massimiliano Di Filippo; Antongiulio Gallina; Barbara Picconi; Jeannette N Stankowski; Yingfei Wang; Ted M Dawson
New synaptic and molecular targets for neuroprotection in Parkinson's disease.
Ishrat Ahmed; Ted M Dawson; Valina Dawson; Yideng Liang; Sabitha Schools; Joseph M Savitt
Development and characterization of a new Parkinson's disease model resulting from impaired autophagy.

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2013: M Scott Vandiver; Risheng Xu; Han Seok Ko; Yun Il Lee; Ted M Dawson; Valina Dawson; Senthilkumar Karuppagounder; Bindu D Paul; Feng Rao; Nilkantha Sen; Adele M Snowman; Solomon H Snyder
Sulfhydration mediates neuroprotective actions of parkin.
Nature communications 2013;4():1626.
2013: Paolo Calabresi; Valina Dawson; Massimiliano Di Filippo; Antongiulio Gallina; Barbara Picconi; Jeannette N Stankowski; Yingfei Wang; Ted M Dawson
New synaptic and molecular targets for neuroprotection in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2013;28(1):51-60.
2012: Ishrat Ahmed; Ted M Dawson; Valina Dawson; Yideng Liang; Sabitha Schools; Joseph M Savitt
Development and characterization of a new Parkinson's disease model resulting from impaired autophagy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(46):16503-9.
2012: Maged Harraz; XueQing Wang; Ted M Dawson; Stephen M Eacker; Valina Dawson
MicroRNA-223 is neuroprotective by targeting glutamate receptors.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(46):18962-7.
2012: Yulan Xiong; Valina Dawson; Ted M Dawson
LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.
Biochemical Society transactions 2012;40(5):1074-9.
2012: Yunjong Lee; Valina Dawson; Ted M Dawson
Animal models of Parkinson's disease: vertebrate genetics.
Cold Spring Harbor perspectives in medicine 2012;2(10):.
2012: Oliver Cooper; Ted M Dawson; Valina Dawson; Michela Deleidi; Jian Feng; John Graziotto; Cristina Guardia-Laguarta; Gunnar Hargus; Zhigao Huang; Shaida Andrabi; Helle Bogetofte; Luis Carrillo-Reid; Li Chen; Lorraine Clark; Houbo Jiang; Christine Klein; Dimitri Krainc; Tristan Lawson; Virginia M-Y Lee; Karen Marder; Joseph Mazzulli; Jesse R McLean; Carol Moskowitz; Grzegorz Opala; Teresia Osborn; Eduardo Perez-Torres; Serge Przedborski; Norma Romero; Owen A Ross; Leslie A Scarffe; Hyemyung Seo; Maria Sundberg; D James Surmeier; John Q Trojanowski; Ryan J Uitti; Laura Volpicelli-Daley; Zbigniew K Wszolek; Zhong Xie; Ole Isacson
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.
Science translational medicine 2012;4(141):141ra90.
2012: Byoung Dae Lee; Valina Dawson; Ted M Dawson
Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease.
Trends in pharmacological sciences 2012;33(7):365-73.
2012: João Paulo L Daher; Ted M Dawson; Valina Dawson; Dagmar Galter; Sandra Gellhaar; Michael K Lee; Alessandra Musso; Olga Pletnikova; Juan C Troncoso; Saskia Biskup; Darren J Moore
Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2.
Human molecular genetics 2012;21(11):2420-31.
2012: Zhikai Chi; Ted M Dawson; Seth Blackshaw; Sean T Byrne; Andrew Dolinko; Nicholas Gaiano; Maged Harraz; Akinori Tokunaga; Jing Xu; Jian-Min Zhang; Valina Dawson
Botch promotes neurogenesis by antagonizing Notch.
Developmental cell 2012;22(4):707-20.
2012: Yulan Xiong; Changqing Yuan; Rong Chen; Ted M Dawson; Valina Dawson
ArfGAP1 is a GTPase activating protein for LRRK2: reciprocal regulation of ArfGAP1 by LRRK2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(11):3877-86.
2012: Nathan Pankratz; Haydeh Payami; Owen A Ross; Clemens R Scherzer; William Scott; David K Simon; Caroline Tanner; Jeffery Vance; Zbigniew K Wszolek; Cyrus Zabetian; Gary Beecham; LN Clark; Ted M Dawson; Anita L DeStefano; Kimberly F Doheny; Stewart A Factor; Tatiana Foroud; Taye H Hamza; Albert Y Hung; Bradley T Hyman; Adrian J Ivinson; Dmitri Krainc; Jeanne C Latourelle; Karen Marder; Eden R Martin; Richard Mayeux; Richard H Myers
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
Annals of neurology 2012;71(3):370-84.
2012: Jeannette N Stankowski; Valina Dawson; Ted M Dawson
Ironing out tau's role in parkinsonism.
Nature medicine 2012;18(2):197-8.
2012: Selina Wray; Zbigniew K Wszolek; Suzanne Barker; Bradley F Boeve; Kevin Boylan; Lorraine N Clark; Roderick A Corriveau; Michael D'Andrea; Ted M Dawson; Michael J Devine; Alberto J Espay; Steven Finkbeiner; Melissa Gerstenhaber; Ludwig Gutmann; Mark Guttman; Katrina Gwinn; Daniel Healy; Henry Houlden; Ole Isacson; Barbara Jasinska-Myga; Patrick A Lewis; Yuying Liang; Colin J Mahoney; Nicholas J Maragakis; Karen S Marder; Jose-Felix Marti-Masso; Huw R Morris; Christer Nilsson; Grzegorz Opala; Elisavet Preza; Serge E Przedborski; Andreas Puschmann; Owen A Ross; Martin N Rossor; Jeffrey rothstein; Natalie S Ryan; Anthony H V Schapira; Matthew Self; Una-Marie Sheerin; Jaroslaw Slawek; A Jon Stoessl; Margaret Sutherland; Jan-Willem Taanman; Ryan J Uitti; Jay Van Gerpen; John Hardy
Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.
PloS one 2012;7(8):e43099.
2012: Elena V Nikonova; Valina Dawson; David J Stone; Eva M Finney; Jonathan T Kern; Keith Q Tanis; Ian J Reynolds; Yulan Xiong; Robert L Vogel; Ted M Dawson
Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity.
Human molecular genetics 2012;21(1):163-74.
2012: Byoung Dae Lee; Xiaojie Li; Ted M Dawson; Valina Dawson
Measuring the activity of leucine-rich repeat kinase 2: a kinase involved in Parkinson's disease.
Methods in molecular biology (Clifton, N.J.) 2012;795():45-54.
2012: L Galluzzi; E S Alnemri; J Yuan; H-U Simon; X Lu; M Piacentini; P Mehlen; R A Knight; I Vitale; Valina Dawson; E H Baehrecke; B Zhivotovsky; J M Abrams; Y Shi; M E Peter; E White; G Melino; S Fulda; S Kumar; M O Hengartner; Ted M Dawson; David C Rubinsztein; G Nuñez; P Vandenabeele; F Madeo; S A Lipton; W Malorni; O Kepp; E Gottlieb; W S El-Deiry; D R Green; M V Blagosklonny; G Kroemer
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012.
Cell death and differentiation 2012;19(1):107-20.
2011: Nigel Ramsden; Zhao Ren; Danny Tam; Nico Zinn; Marcus Bantscheff; Frederique Bard; Michael Bova; Ted M Dawson; Valina Dawson; Gerard Drewes; Manja Lang; Byoung Dae Lee; Jessica Perrin; Carsten Hopf
Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons.
ACS chemical biology 2011;6(10):1021-8.
2011: Zhaohui Liu; Arpita Ray; Wanli Smith; Dejun Yang; Byoung Dae Lee; Guy A Caldwell; Kim A Caldwell; Ted M Dawson; Shusei Hamamichi; Valina Dawson
Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models.
Human molecular genetics 2011;20(20):3933-42.
2011: Maged Harraz; Ted M Dawson; Valina Dawson
MicroRNAs in Parkinson's disease.
Journal of chemical neuroanatomy 2011;42(2):127-30.
2011: Katherine C M Chew; Ted M Dawson; Valina Dawson; Kah Leong Lim; Shun Qiang Lo; Elijah Ong; Wei-Yi Ong; Han-Ming Shen; Yee Kit Tai; Fai Tsang; Eng-Tat Ang; Tuck Wah Soong
Enhanced autophagy from chronic toxicity of iron and mutant A53T α-synuclein: implications for neuronal cell death in Parkinson disease.
The Journal of biological chemistry 2011;286(38):33380-9.
2011: Ian Martin; Valina Dawson; Ted M Dawson
Recent advances in the genetics of Parkinson's disease.
Annual review of genomics and human genetics 2011;12():301-25.
2011: Ho Chul Kang; Han Seok Ko; Byoung Dae Lee; Yunjong Lee; Yun-Il Lee; Guy G Poirier; Joo-Ho Shin; Shaida A Andrabi; Zhikai Chi; Valina Dawson; Jean-Philippe Gagné; Ted M Dawson
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(34):14103-8.
2011: Ted M Dawson; Valina Dawson
A lysosomal lair for a pathogenic protein pair.
Science translational medicine 2011;3(91):91ps28.
2011: Shaida A Andrabi; Zhikai Chi; Ted M Dawson; Jean-François Haince; Ho Chul Kang; Raymond C Koehler; Yun-Il Lee; Guy G Poirier; Andrew B West; Jian-Min Zhang; Valina Dawson
Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death.
Nature medicine 2011;17(6):692-9.
2011: Jian-Min Zhang; Yue Wang; Zhikai Chi; Matthew J Keuss; Ying-Min Emily Pai; Ho Chul Kang; Joo-Ho Shin; Artem Bugayenko; Hong Wang; Yulan Xiong; Mikhail V Pletnikov; Mark P Mattson; Ted M Dawson; Valina Dawson
The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior.
Cell 2011;145(2):284-99.
2011: Joo-Ho Shin; Han Seok Ko; Hochul Kang; Yunjong Lee; Yun-Il Lee; Olga Pletinkova; Juan C Troconso; Valina Dawson; Ted M Dawson
PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease.
Cell 2011;144(5):689-702.
2011: Stephen M Eacker; Matthew J Keuss; Eugene Berezikov; Valina Dawson; Ted M Dawson
Neuronal activity regulates hippocampal miRNA expression.
PloS one 2011;6(10):e25068.
2011: David Ramonet; João Paulo L Daher; Brian M Lin; Klodjan Stafa; Jaekwang Kim; Rebecca Banerjee; Marie Westerlund; Olga Pletnikova; Liliane Glauser; Lichuan Yang; Ying Liu; Deborah A Swing; M Flint Beal; Juan C Troncoso; J Michael McCaffery; Nancy A Jenkins; Neal G Copeland; Dagmar Galter; Bobby Thomas; Michael K Lee; Ted M Dawson; Valina Dawson; Darren J Moore
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.
PloS one 2011;6(4):e18568.
2011: Yingfei Wang; No Soo Kim; Jean-Francois Haince; Ho Chul Kang; Karen K David; Shaida A Andrabi; Guy G Poirier; Valina Dawson; Ted M Dawson
Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos).
Science signaling 2011;4(167):ra20.
2011: Bobby Thomas; Allen S Mandir; Neva West; Ying Liu; Shaida A Andrabi; Wanda Stirling; Valina Dawson; Ted M Dawson; Michael K Lee
Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation.
PloS one 2011;6(1):e16706.
2010: Bharathi S Gadad; João P L Daher; Eric K Hutchinson; CORY BRAYTON; Ted M Dawson; Mikhail V Pletnikov; Julie Watson
Effect of fenbendazole on three behavioral tests in male C57BL/6N mice.
Journal of the American Association for Laboratory Animal Science : JAALAS 2010;49(6):821-5.
2010: Han Seok Ko; Yunjong Lee; Joo-Ho Shin; Senthilkumar S Karuppagounder; Bharathi Shrikanth Gadad; Anthony J Koleske; Olga Pletnikova; Juan C Troncoso; Valina Dawson; Ted M Dawson
Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(38):16691-6.
2010: Xiaojie Li; Darren J Moore; Yulan Xiong; Ted M Dawson; Valina Dawson
Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2.
The Journal of biological chemistry 2010;285(38):29569-76.
2010: Byoung Dae Lee; Joo-Ho Shin; Jackalina VanKampen; Leonard Petrucelli; Andrew B West; Han Seok Ko; Yun-Il Lee; Kathleen A Maguire-Zeiss; William J Bowers; Howard Federoff; Valina Dawson; Ted M Dawson
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease.
Nature medicine 2010;16(9):998-1000.
2010: Sika Zheng; Stephen M Eacker; Suk Jin Hong; Richard M Gronostajski; Ted M Dawson; Valina Dawson
NMDA-induced neuronal survival is mediated through nuclear factor I-A in mice.
The Journal of clinical investigation 2010;120(7):2446-56.
2010: Zhenfeng Xu; Jian-Min Zhang; Karen K David; Zeng Jin Yang; Xiaoling Li; Ted M Dawson; Valina Dawson; Raymond C Koehler
Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;299(1):R215-21.
2010: Ted M Dawson; Han Seok Ko; Valina Dawson
Genetic animal models of Parkinson's disease.
Neuron 2010;66(5):646-61.
2010: Wanli Smith; Zhaohui Liu; Yideng Liang; Naoki Masuda; Debbie A Swing; Nancy A Jenkins; Neal G Copeland; Juan C Troncoso; Mikhail V Pletnikov; Ted M Dawson; Lee J Martin; Timothy H Moran; Michael K Lee; David R Borchelt; Christopher A Ross
Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model.
Human molecular genetics 2010;19(11):2087-98.
2010: Xiaoling Li; Judith A Klaus; Jian-Min Zhang; Zhenfeng Xu; Kathleen K Kibler; Shaida A Andrabi; Karthik Rao; Zeng Jin Yang; Ted M Dawson; Valina Dawson; Raymond C Koehler
Contributions of poly(ADP-ribose) polymerase-1 and -2 to nuclear translocation of apoptosis-inducing factor and injury from focal cerebral ischemia.
Journal of neurochemistry 2010;113(4):1012-22.
2010: Yulan Xiong; Candice E Coombes; Austin Kilaru; Xiaojie Li; Aaron D Gitler; William J Bowers; Valina Dawson; Ted M Dawson; Darren J Moore
GTPase activity plays a key role in the pathobiology of LRRK2.
PLoS genetics 2010;6(4):e1000902.
2010: Cristofol Vives-Bauza; Chun Zhou; Yong Huang; Mei Cui; Rosa L A de Vries; Jiho Kim; Jessica May; Maja Aleksandra Tocilescu; Wencheng Liu; Han Seok Ko; Jordi Magrané; Darren J Moore; Valina Dawson; Regis Grailhe; Ted M Dawson; Chenjian Li; Kim Tieu; Serge Przedborski
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(1):378-83.
2010: Cheng Dai; Dong Liang; Huiwu Li; Masayuki Sasaki; Ted M Dawson; Valina Dawson
Functional identification of neuroprotective molecules.
PloS one 2010;5(11):e15008.
2010: Ian Martin; Valina Dawson; Ted M Dawson
The impact of genetic research on our understanding of Parkinson's disease.
Progress in brain research 2010;183():21-41.
2010: Ted M Dawson; Valina Dawson
The role of parkin in familial and sporadic Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2010;25 Suppl 1():S32-9.
2009: Eva Andres-Mateos; Rebeca Mejias; Masayuki Sasaki; Xiaojie Li; Brian M Lin; Saskia Biskup; Li Zhang; Rebecca Banerjee; Bobby Thomas; Lichuan Yang; Guosheng Liu; M Flint Beal; David L Huso; Ted M Dawson; Valina Dawson
Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(50):15846-50.
2009: Stephen M Eacker; Ted M Dawson; Valina Dawson
Understanding microRNAs in neurodegeneration.
Nature reviews. Neuroscience 2009;10(12):837-41.
2009: Joo-Ho Shin; Valina Dawson; Ted M Dawson
SnapShot: pathogenesis of Parkinson's disease.
Cell 2009;139(2):440.e1-2.
2009: Tuan Hoang; Dong-Kug Choi; Makiko Nagai; Du-Chu Wu; Tetsuya Nagata; Delphine Prou; Glenn L Wilson; Miquel Vila; Vernice Jackson-Lewis; Valina Dawson; Ted M Dawson; Marie-Francoise Chesselet; Serge Przedborski
Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease.
Free radical biology & medicine 2009;47(7):1049-56.
2009: Chee-Hoe Ng; Shaun Z S Mok; Cherlyn Koh; Xuezhi Ouyang; Marc L Fivaz; Eng-King Tan; Valina Dawson; Ted M Dawson; Fengwei Yu; Kah Leong Lim
Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(36):11257-62.
2009: Shinji Higashi; Darren J Moore; Ryoko Yamamoto; Michiko Minegishi; Kiyoshi Sato; Takashi Togo; Omi Katsuse; Hirotake Uchikado; Yoshiko Furukawa; Hiroaki Hino; Kenji Kosaka; Piers C Emson; Keiji Wada; Valina Dawson; Ted M Dawson; Heii Arai; Eizo Iseki
Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease.
Journal of neuropathology and experimental neurology 2009;68(9):994-1005.
2009: Yingfei Wang; Valina Dawson; Ted M Dawson
Poly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos.
Experimental neurology 2009;218(2):193-202.
2009: Ted M Dawson; Darren J Moore; Andrew B West
Revelations and revolutions in the understanding of Parkinson's disease.
Biochimica et biophysica acta 2009;1792(7):585-6.
2009: Elisa A Waxman; Jason P Covy; Irene Bukh; Xiaojie Li; Ted M Dawson; Benoit I Giasson
Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusions.
Journal of neuropathology and experimental neurology 2009;68(7):785-96.
2009: Yingfei Wang; No S Kim; Xiaoling Li; Peter A Greer; Raymond C Koehler; Valina Dawson; Ted M Dawson
Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos).
Journal of neurochemistry 2009;110(2):687-96.
2009: Anthony H K Tsang; Yun-Il Lee; Han Seok Ko; Joseph M Savitt; Olga Pletnikova; Juan C Troncoso; Valina Dawson; Ted M Dawson; Kenny K K Chung
S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(12):4900-5.
2009: Han Seok Ko; Rachel Bailey; Wanli Smith; Zhaohui Liu; Joo-Ho Shin; Yun-Il Lee; Yong-Jie Zhang; Haibing Jiang; Christopher A Ross; Darren J Moore; Winston Patterson; Leonard Petrucelli; Ted M Dawson; Valina Dawson
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2897-902.
2009: Seong-Woon Yu; Yingfei Wang; Didrik S Frydenlund; Ole Petter Ottersen; Valina Dawson; Ted M Dawson
Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release.
ASN neuro 2009;1(5):.
2009: João Paulo L Daher; Mingyao Ying; Rebecca Banerjee; Rebecca S McDonald; Myriam Dumas Hahn; Lichuan Yang; M Flint Beal; Bobby Thomas; Valina Dawson; Ted M Dawson; Darren J Moore
Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons.
Molecular neurodegeneration 2009;4():34.
2009: Karen Kate David; Shaida A Andrabi; Ted M Dawson; Valina Dawson
Parthanatos, a messenger of death.
Frontiers in bioscience : a journal and virtual library 2009;14():1116-28.
2008: Amitabh Gupta; Valina Dawson; Ted M Dawson
What causes cell death in Parkinson's disease?
Annals of neurology 2008;64 Suppl 2():S3-15.
2008: Shaida A Andrabi; Ted M Dawson; Valina Dawson
Mitochondrial and nuclear cross talk in cell death: parthanatos.
Annals of the New York Academy of Sciences 2008;1147():233-41.
2008: Jean-Philippe Gagné; Maxim Isabelle; Ken Sin Lo; Sylvie Bourassa; Michael J Hendzel; Valina Dawson; Ted M Dawson; Guy G Poirier
Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes.
Nucleic acids research 2008;36(22):6959-76.
2008: Esther S P Wong; Jeanne Tan; Wen-E Soong; Kamila Hussein; Nobuyuki Nukina; Valina Dawson; Ted M Dawson; Ana Maria Cuervo; Kah Leong Lim
Autophagy-mediated clearance of aggresomes is not a universal phenomenon.
Human molecular genetics 2008;17(16):2570-82.
2008: Darren J Moore; Ted M Dawson
Value of genetic models in understanding the cause and mechanisms of Parkinson's disease.
Current neurology and neuroscience reports 2008;8(4):288-96.
2008: Nilkantha Sen; Makoto R Hara; Michael D Kornberg; Matthew Cascio; Byoung-Il Bae; Neelam Shahani; Bobby Thomas; Ted M Dawson; Valina Dawson; Solomon H Snyder; Akira Sawa
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis.
Nature cell biology 2008;10(7):866-73.
2008: Ted M Dawson
Non-autonomous cell death in Parkinson's disease.
Lancet neurology 2008;7(6):474-5.
2008: Samy Habib; David Michel; Eliezer Masliah; Bobby Thomas; Han Seok Ko; Ted M Dawson; Hanna Abboud; Robert Clark; Syed Z Imam
Role of tuberin in neuronal degeneration.
Neurochemical research 2008;33(6):1113-6.
2008: Darren J Moore; Andrew B West; Dustin A Dikeman; Valina Dawson; Ted M Dawson
Parkin mediates the degradation-independent ubiquitination of Hsp70.
Journal of neurochemistry 2008;105(5):1806-19.
2008: Gay Rudow; Richard J O'Brien; Alena V Savonenko; Susan M Resnick; Alan B Zonderman; Olga Pletnikova; Laura Marsh; Ted M Dawson; Barbara J Crain; Mark J West; Juan C Troncoso
Morphometry of the human substantia nigra in ageing and Parkinson's disease.
Acta neuropathologica 2008;115(4):461-70.
2008: Lizhen Wang; Chengsong Xie; Elisa Greggio; Loukia Parisiadou; Hoon Shim; Lixin Sun; Jayanth Chandran; Xian Lin; Chen Lai; Wan-Jou Yang; Darren J Moore; Ted M Dawson; Valina Dawson; Gabriela Chiosis; Mark Cookson; Huaibin Cai
The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(13):3384-91.
2008: Maged Harraz; Ted M Dawson; Valina Dawson
Advances in neuronal cell death 2007.
Stroke; a journal of cerebral circulation 2008;39(2):286-8.
2008: Jeanne Tan; Esther S P Wong; Donald Kirkpatrick; Olga Pletnikova; Han Seok Ko; Shiam-Peng Tay; Michelle W L Ho; Juan C Troncoso; Steven P Gygi; Michael K Lee; Valina Dawson; Ted M Dawson; Kah Leong Lim
Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases.
Human molecular genetics 2008;17(3):431-9.
2007: Haibing Jiang; Yen-Ching Wu; Masayuki Nakamura; Yideng Liang; Yuji Tanaka; Susan E Holmes; Valina Dawson; Ted M Dawson; Christopher A Ross; Wanli Smith
Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death.
Neurobiology of aging 2007;28(11):1709-17.
2007: Mark Cookson; William T Dauer; Ted M Dawson; Edward A Fon; Ming Guo; Jie Shen
The roles of kinases in familial Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(44):11865-8.
2007: Eva Andres-Mateos; Celine Perier; Li Zhang; Beatrice Blanchard-Fillion; Todd M Greco; Bobby Thomas; Han Seok Ko; Masayuki Sasaki; Harry Ischiropoulos; Serge Przedborski; Ted M Dawson; Valina Dawson
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(37):14807-12.
2007: Marc F Poitras; David W Koh; Seong-Woon Yu; Shaida A Andrabi; Allen S Mandir; Guy G Poirier; Valina Dawson; Ted M Dawson
Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain.
Neuroscience 2007;148(1):198-211.
2007: Shinji Higashi; Saskia Biskup; Andrew B West; Daniel Trinkaus; Valina Dawson; Richard L M Faull; Henry J Waldvogel; Heii Arai; Ted M Dawson; Darren J Moore; Piers C Emson
Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain.
Brain research 2007;1155():208-19.
2007: Wenqin Luo; S Rasika Wickramasinghe; Joseph M Savitt; John W Griffin; Ted M Dawson; David D Ginty
A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.
Neuron 2007;54(5):739-54.
2007: Jean-François Haince; Sergei Kozlov; Valina Dawson; Ted M Dawson; Michael Hendzel; Martin F Lavin; Guy G Poirier
Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents.
The Journal of biological chemistry 2007;282(22):16441-53.
2007: Bobby Thomas; Rainer Von Coelln; Allen S Mandir; Daniel B Trinkaus; Mohamed H Farah; Kah Leong Lim; Noel Y Calingasan; M Flint Beal; Valina Dawson; Ted M Dawson
MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.
Neurobiology of disease 2007;26(2):312-22.
2007: Esther S P Wong; Jeanne Tan; Cheng Wang; Zhenshui Zhang; Shiam-Peng Tay; Norazean Zaiden; Han Seok Ko; Valina Dawson; Ted M Dawson; Kah Leong Lim
Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations.
The Journal of biological chemistry 2007;282(16):12310-8.
2007: Andrew B West; Darren J Moore; Catherine Choi; Shaida A Andrabi; Xiaojie Li; Dustin Dikeman; Saskia Biskup; Zhenshui Zhang; Kah Leong Lim; Valina Dawson; Ted M Dawson
Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity.
Human molecular genetics 2007;16(2):223-32.
2007: Xiaoling Li; Masaaki Nemoto; Z Xu; Seong-Woon Yu; Mika Shimoji; Shaida A Andrabi; Jean-François Haince; Guy G Poirier; Ted M Dawson; Valina Dawson; Raymond C Koehler
Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus.
Neuroscience 2007;144(1):56-65.
2007: Ted M Dawson
Unraveling the role of defective genes in Parkinson's disease.
Parkinsonism & related disorders 2007;13 Suppl 3():S248-9.
2007: Saskia Biskup; Darren J Moore; Alexis Rea; Bettina Lorenz-Deperieux; Candice E Coombes; Valina Dawson; Ted M Dawson; Andrew B West
Dynamic and redundant regulation of LRRK2 and LRRK1 expression.
BMC neuroscience 2007;8():102.
2007: Amitabh Gupta; Ted M Dawson
The role of stem cells in Parkinson's disease.
Neurosurgery clinics of North America 2007;18(1):129-42, x-xi.
2007: Shinji Higashi; Darren J Moore; Rebecca E Colebrooke; Saskia Biskup; Valina Dawson; Heii Arai; Ted M Dawson; Piers C Emson
Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain.
Journal of neurochemistry 2007;100(2):368-81.
2006: Valina Dawson; Ted M Dawson
Mining for survival genes.
Biochemical Society transactions 2006;34(Pt 6):1307-9.
2006: Shaida A Andrabi; No Soo Kim; Seong-Woon Yu; Hongmin Wang; David W Koh; Masayuki Sasaki; Judith A Klaus; Takashi Otsuka; Zhizheng Zhang; Raymond C Koehler; Patricia D Hurn; Guy G Poirier; Valina Dawson; Ted M Dawson
Poly(ADP-ribose) (PAR) polymer is a death signal.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18308-13.
2006: Seong-Woon Yu; Shaida A Andrabi; Hongmin Wang; No Soo Kim; Guy G Poirier; Ted M Dawson; Valina Dawson
Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18314-9.
2006: Saskia Biskup; Darren J Moore; Fulvio Celsi; Shinji Higashi; Andrew B West; Shaida A Andrabi; Kaisa Kurkinen; Seong-Woon Yu; Joseph M Savitt; Henry J Waldvogel; Richard L M Faull; Piers C Emson; Reidun Torp; Ole Petter Ottersen; Ted M Dawson; Valina Dawson
Localization of LRRK2 to membranous and vesicular structures in mammalian brain.
Annals of neurology 2006;60(5):557-69.
2006: Wanli Smith; Zhong Pei; Haibing Jiang; Valina Dawson; Ted M Dawson; Christopher A Ross
Kinase activity of mutant LRRK2 mediates neuronal toxicity.
Nature neuroscience 2006;9(10):1231-3.
2006: Ted M Dawson; Valina Dawson
Taming the clot-buster tPA.
Nature medicine 2006;12(9):993-4.
2006: Joseph M Savitt; Valina Dawson; Ted M Dawson
Diagnosis and treatment of Parkinson disease: molecules to medicine.
The Journal of clinical investigation 2006;116(7):1744-54.
2006: K K David; Masayuki Sasaki; Seong-Woon Yu; Ted M Dawson; Valina Dawson
EndoG is dispensable in embryogenesis and apoptosis.
Cell death and differentiation 2006;13(7):1147-55.
2006: Han Seok Ko; Seong Who Kim; Sathya R Sriram; Valina Dawson; Ted M Dawson
Identification of far upstream element-binding protein-1 as an authentic Parkin substrate.
The Journal of biological chemistry 2006;281(24):16193-6.
2006: Jeanne Tan; Ted M Dawson
Parkin blushed by PINK1.
Neuron 2006;50(4):527-9.
2006: Rainer Von Coelln; Bobby Thomas; Shaida A Andrabi; Kah Leong Lim; Joseph M Savitt; Roya Saffary; Wanda Stirling; Kristy J Bruno; Ellen J Hess; Michael K Lee; Valina Dawson; Ted M Dawson
Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(14):3685-96.
2006: Kah Leong Lim; Valina Dawson; Ted M Dawson
Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?
Neurobiology of aging 2006;27(4):524-9.
2006: Makoto R Hara; Bobby Thomas; Matthew Cascio; Byoung-Il Bae; Lynda D Hester; Valina Dawson; Ted M Dawson; Akira Sawa; Solomon H Snyder
Neuroprotection by pharmacologic blockade of the GAPDH death cascade.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3887-9.
2006: Antonella Riccio; Rebecca S Alvania; Bonnie E Lonze; Narendrakumar Ramanan; Taeho Kim; Yunfei Huang; Ted M Dawson; Solomon H Snyder; David D Ginty
A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons.
Molecular cell 2006;21(2):283-94.
2006: Darren J Moore; Valina Dawson; Ted M Dawson
Lessons from Drosophila models of DJ-1 deficiency.
Science of aging knowledge environment : SAGE KE 2006;2006(2):pe2.
2006: Ted M Dawson
Parkin and defective ubiquitination in Parkinson's disease.
Journal of neural transmission. Supplementum 2006;(70):209-13.
2006: Li Zhang; Valina Dawson; Ted M Dawson
Role of nitric oxide in Parkinson's disease.
Pharmacology & therapeutics 2006;109(1-2):33-41.
2005: Wanli Smith; Zhong Pei; Haibing Jiang; Darren J Moore; Yideng Liang; Andrew B West; Valina Dawson; Ted M Dawson; Christopher A Ross
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(51):18676-81.
2005: Cheng Wang; Han Seok Ko; Bobby Thomas; Fai Tsang; Katherine C M Chew; Shiam-Peng Tay; Michelle W L Ho; Tit Meng Lim; Tuck Wah Soong; Olga Pletnikova; Juan C Troncoso; Valina Dawson; Ted M Dawson; Kah Leong Lim
Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function.
Human molecular genetics 2005;14(24):3885-97.
2005: Wanli Smith; Haibing Jiang; Zhong Pei; Yuji Tanaka; Hokuto Morita; Akira Sawa; Valina Dawson; Ted M Dawson; Christopher A Ross
Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity.
Human molecular genetics 2005;14(24):3801-11.
2005: Ted M Dawson
Failures and successes of clinical trials for Parkinson disease treatments.
Retina (Philadelphia, Pa.) 2005;25(8 Suppl):S75-S77.
2005: Andrew B West; Darren J Moore; Saskia Biskup; Artem Bugayenko; Wanli Smith; Christopher A Ross; Valina Dawson; Ted M Dawson
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16842-7.
2005: Kenny K K Chung; Ted M Dawson; Valina Dawson
Nitric oxide, S-nitrosylation and neurodegeneration.
Cellular and molecular biology (Noisy-le-Grand, France) 2005;51(3):247-54.
2005: Sathya R Sriram; Xiaojie Li; Han Seok Ko; Kenny K K Chung; Esther Wong; Kah Leong Lim; Valina Dawson; Ted M Dawson
Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.
Human molecular genetics 2005;14(17):2571-86.
2005: Daniela Berg; Marc Niwar; Sylvia Maass; Alexander Zimprich; J Carsten Möller; Ullrich Wüllner; Tanja Schmitz-Hübsch; Christine Klein; Eng-King Tan; Ludger Schöls; Laura Marsh; Ted M Dawson; Bernd Janetzky; Thomas Müller; Dirk Woitalla; Vladimir Kostic; Peter P Pramstaller; Wolfgang H Oertel; Peter Bauer; Rejko Krueger; Thomas Gasser; Olaf Riess
Alpha-synuclein and Parkinson's disease: implications from the screening of more than 1,900 patients.
Movement disorders : official journal of the Movement Disorder Society 2005;20(9):1191-4.
2005: Han Seok Ko; Rainer Von Coelln; Sathya R Sriram; Seong Who Kim; Kenny K K Chung; Olga Pletnikova; Juan C Troncoso; Brett Johnson; Roya Saffary; Eyleen L K Goh; Hongjun Song; Bum-Joon Park; Min Jung Kim; Sunghoon Kim; Valina Dawson; Ted M Dawson
Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(35):7968-78.
2005: Jin H Son; Hibiki Kawamata; Myung S Yoo; Dae Joon Kim; Young K Lee; Sooyoul Kim; Ted M Dawson; Hui Zhang; David Sulzer; Lichuan Yang; M Flint Beal; Lorraine A DeGiorgio; Hong Sung Chun; Harriet Baker; Chu Peng
Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons.
Journal of neurochemistry 2005;94(4):1040-53.
2005: Olga Pletnikova; Neva West; Michael K Lee; Gay Rudow; Richard L Skolasky; Ted M Dawson; Laura Marsh; Juan C Troncoso
Abeta deposition is associated with enhanced cortical alpha-synuclein lesions in Lewy body diseases.
Neurobiology of aging 2005;26(8):1183-92.
2005: Joseph M Savitt; Susie S Jang; Weitong Mu; Valina Dawson; Ted M Dawson
Bcl-x is required for proper development of the mouse substantia nigra.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(29):6721-8.
2005: Li Zhang; Mika Shimoji; Bobby Thomas; Darren J Moore; Seong-Woon Yu; Neena I Marupudi; Reidun Torp; Ingeborg A Torgner; Ole Petter Ottersen; Ted M Dawson; Valina Dawson
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis.
Human molecular genetics 2005;14(14):2063-73.
2005: Andrew B West; Valina Dawson; Ted M Dawson
To die or grow: Parkinson's disease and cancer.
Trends in neurosciences 2005;28(7):348-52.
2005: David W Koh; Ted M Dawson; Valina Dawson
Mediation of cell death by poly(ADP-ribose) polymerase-1.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;52(1):5-14.
2005: Olga Pol; Masayuki Sasaki; Natàlia Jiménez; Valina Dawson; Ted M Dawson; Margarita M Puig
The involvement of nitric oxide in the enhanced expression of mu-opioid receptors during intestinal inflammation in mice.
British journal of pharmacology 2005;145(6):758-66.
2005: Wanli Smith; Russell L Margolis; Xiaojie Li; Juan C Troncoso; Michael K Lee; Valina Dawson; Ted M Dawson; Takeshi Iwatsubo; Christopher A Ross
Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(23):5544-52.
2005: David W Koh; Ted M Dawson; Valina Dawson
Poly(ADP-ribosyl)ation regulation of life and death in the nervous system.
Cellular and molecular life sciences : CMLS 2005;62(7-8):760-8.
2005: Cheng Wang; Jeanne Tan; Michelle W L Ho; Norazean Zaiden; Siew Heng Wong; Constance L C Chew; Pei Woon Eng; Tit Meng Lim; Ted M Dawson; Kah Leong Lim
Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations.
Journal of neurochemistry 2005;93(2):422-31.
2005: Mika Shimoji; Li Zhang; Allen S Mandir; Valina Dawson; Ted M Dawson
Absence of inclusion body formation in the MPTP mouse model of Parkinson's disease.
Brain research. Molecular brain research 2005;134(1):103-8.
2005: David W Koh; Valina Dawson; Ted M Dawson
The road to survival goes through PARG.
Cell cycle (Georgetown, Tex.) 2005;4(3):397-9.
2005: Kah Leong Lim; Katherine C M Chew; Jeanne Tan; Cheng Wang; Kenny K K Chung; Yi Zhang; Yuji Tanaka; Wanli Smith; Simone Engelender; Christopher A Ross; Valina Dawson; Ted M Dawson
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(8):2002-9.
2005: Wei-ping Yu; Jeanne Tan; Katherine C M Chew; Tania Oh; Prasanna Kolatkar; Byrappa Venkatesh; Ted M Dawson; Kah Leong Lim
The 350-fold compacted Fugu parkin gene is structurally and functionally similar to human Parkin.
Gene 2005;346():97-104.
2005: Wenxue Li; Neva West; Emanuela Colla; Olga Pletnikova; Juan C Troncoso; Laura Marsh; Ted M Dawson; Pekka Jäkälä; Tobias Hartmann; Donald L Price; Michael K Lee
Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(6):2162-7.
2005: Suk Hong; Valina Dawson; Ted M Dawson
Identification and evaluation of NO-regulated genes by differential analysis of primary cDNA library expression (DAzLE).
Methods in enzymology 2005;396():359-68.
2005: Kenny K K Chung; Valina Dawson; Ted M Dawson
S-nitrosylation in Parkinson's disease and related neurodegenerative disorders.
Methods in enzymology 2005;396():139-50.
2005: Darren J Moore; Andrew B West; Valina Dawson; Ted M Dawson
Molecular pathophysiology of Parkinson's disease.
Annual review of neuroscience 2005;28():57-87.
2005: Darren J Moore; Li Zhang; Juan C Troncoso; Michael K Lee; Nobutaka Hattori; Yoshikuni Mizuno; Ted M Dawson; Valina Dawson
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress.
Human molecular genetics 2005;14(1):71-84.
2004: David W Koh; Ann M Lawler; Marc F Poitras; Masayuki Sasaki; Sigrid Wattler; Michael Nehls; Tobias Stoeger; Guy G Poirier; Valina Dawson; Ted M Dawson
Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(51):17699-704.
2004: Kenny K K Chung; Ted M Dawson
Parkin and Hsp70 sacked by BAG5.
Neuron 2004;44(6):899-901.
2004: Hongmin Wang; Seong-Woon Yu; David W Koh; Jasmine Lew; Carmen Coombs; William J Bowers; Howard Federoff; Guy G Poirier; Ted M Dawson; Valina Dawson
Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(48):10963-73.
2004: Rainer Von Coelln; Valina Dawson; Ted M Dawson
Parkin-associated Parkinson's disease.
Cell and tissue research 2004;318(1):175-84.
2004: Vassilis E Koliatsos; Ted M Dawson; Aleksandar Kecojevic; Yueping Zhou; Yi-Feei Wang; K-X Huang
Cortical interneurons become activated by deafferentation and instruct the apoptosis of pyramidal neurons.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(39):14264-9.
2004: Henrik Hagberg; Mary Ann Wilson; Hiroko Matsushita; Changlian Zhu; Mary Lange; Malin Gustavsson; Marc F Poitras; Ted M Dawson; Valina Dawson; Frances J Northington; Michael V Johnston
PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury.
Journal of neurochemistry 2004;90(5):1068-75.
2004: Valina Dawson; Ted M Dawson
Deadly conversations: nuclear-mitochondrial cross-talk.
Journal of bioenergetics and biomembranes 2004;36(4):287-94.
2004: Laura Marsh; James Williams; M Rocco; S Grill; Cynthia A Munro; Ted M Dawson
Psychiatric comorbidities in patients with Parkinson disease and psychosis.
Neurology 2004;63(2):293-300.
2004: Rainer Von Coelln; Bobby Thomas; Joseph M Savitt; Kah Leong Lim; Masayuki Sasaki; Ellen J Hess; Valina Dawson; Ted M Dawson
Loss of locus coeruleus neurons and reduced startle in parkin null mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10744-9.
2004: Kenny K K Chung; Bobby Thomas; Xiaojie Li; Olga Pletnikova; Juan C Troncoso; Laura Marsh; Valina Dawson; Ted M Dawson
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function.
Science (New York, N.Y.) 2004;304(5675):1328-31.
2004: Suk Hong; Ted M Dawson; Valina Dawson
Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling.
Trends in pharmacological sciences 2004;25(5):259-64.
2004: Amer Samdani; Eric B Kuchner; Laurence D Rhines; David C Adamson; Christopher Lawson; Betty M. Tyler; Henry Brem; Valina Dawson; Ted M Dawson
Astroglia induce cytotoxic effects on brain tumors via a nitric oxide-dependent pathway both in vitro and in vivo.
Neurosurgery 2004;54(5):1231-7; discussion 1237-8.
2004: Leonard Petrucelli; dennis dickson; Kathryn Kehoe; Julie Taylor; Heather Snyder; Andrew Grover; Michael De Lucia; Eileen McGowan; Jada Lewis; Guy Prihar; Jungsu Kim; Wolfgang H Dillmann; Susan E Browne; Alexis Hall; Richard Voellmy; Yoshio Tsuboi; Ted M Dawson; Benjamin Wolozin; John Hardy; Michael Hutton
CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation.
Human molecular genetics 2004;13(7):703-14.
2004: Dong Liang; Ted M Dawson; Valina Dawson
What have genetically engineered mice taught us about ischemic injury?
Current molecular medicine 2004;4(2):207-25.
2004: Suk Hong; Huiwu Li; Kevin G Becker; Valina Dawson; Ted M Dawson
Identification and analysis of plasticity-induced late-response genes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2145-50.
2004: Huiwu Li; Xiujing Gu; Valina Dawson; Ted M Dawson
Identification of calcium- and nitric oxide-regulated genes by differential analysis of library expression (DAzLE).
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):647-52.
2004: Leonard Petrucelli; Ted M Dawson
Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system.
Annals of medicine 2004;36(4):315-20.
2003: Darren J Moore; Li Zhang; Ted M Dawson; Valina Dawson
A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.
Journal of neurochemistry 2003;87(6):1558-67.
2003: Seong-Woon Yu; Hongmin Wang; Ted M Dawson; Valina Dawson
Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity.
Neurobiology of disease 2003;14(3):303-17.
2003: Aaron C Pawlyk; Benoit I Giasson; Deepak M Sampathu; Francisco A Perez; Kah Leong Lim; Valina Dawson; Ted M Dawson; Richard D Palmiter; John Q Trojanowski; Virginia M-Y Lee
Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.
The Journal of biological chemistry 2003;278(48):48120-8.
2003: Ted M Dawson; Valina Dawson
Molecular pathways of neurodegeneration in Parkinson's disease.
Science (New York, N.Y.) 2003;302(5646):819-22.
2003: Jason Eriksen; Ted M Dawson; dennis dickson; Leonard Petrucelli
Caught in the act: alpha-synuclein is the culprit in Parkinson's disease.
Neuron 2003;40(3):453-6.
2003: Kai Y Xu; Shanmuga P Kuppusamy; Jing Q Wang; Haiquan Li; Hongmei Cui; Ted M Dawson; Paul L Huang; Arthur L Burnett; Periannan Kuppusamy; Lewis C Becker
Nitric oxide protects cardiac sarcolemmal membrane enzyme function and ion active transport against ischemia-induced inactivation.
The Journal of biological chemistry 2003;278(43):41798-803.
2003: Peter Choi; Heather Snyder; Leonard Petrucelli; Catherine Theisler; M Chong; Y Zhang; K Lim; Kenny K K Chung; Kathryn Kehoe; Luciano D'Adamio; John Lee; E Cochran; R Bowser; Ted M Dawson; Benjamin Wolozin
SEPT5_v2 is a parkin-binding protein.
Brain research. Molecular brain research 2003;117(2):179-89.
2003: Kenny K K Chung; Valina Dawson; Ted M Dawson
New insights into Parkinson's disease.
Journal of neurology 2003;250 Suppl 3():III15-24.
2003: Darren J Moore; Valina Dawson; Ted M Dawson
Genetics of Parkinson's disease: what do mutations in DJ-1 tell us?
Annals of neurology 2003;54(3):281-2.
2003: Hongmin Wang; Mika Shimoji; Seong-Woon Yu; Ted M Dawson; Valina Dawson
Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease.
Annals of the New York Academy of Sciences 2003;991():132-9.
2003: Kah Leong Lim; Valina Dawson; Ted M Dawson
The cast of molecular characters in Parkinson's disease: felons, conspirators, and suspects.
Annals of the New York Academy of Sciences 2003;991():80-92.
2003: Jin Woong Chung; Suk Hong; Kee Jun Kim; Daniel Goti; Monique F Stins; Sooan Shin; Valina Dawson; Ted M Dawson; Kwang S Kim
37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake.
The Journal of biological chemistry 2003;278(19):16857-62.
2003: Bernard Ravina; Susan C Fagan; Robert Hart; C A Hovinga; Diane D Murphy; Ted M Dawson; John R Marler
Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment.
Neurology 2003;60(8):1234-40.
2003: Frederick C Nucifora; Lisa M Ellerby; Cheryl L Wellington; Jonathan D Wood; William Joseph Herring; Akira Sawa; Michael R Hayden; Valina Dawson; Ted M Dawson; Christopher A Ross
Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity.
The Journal of biological chemistry 2003;278(15):13047-55.
2003: Yihru Fannjiang; Chong-Hyun Kim; Richard Huganir; Shifa Zou; Tullia Lindsten; Craig Thompson; Toshiaki Mito; Richard J Traystman; Thomas Larsen; Diane E Griffin; Allen S Mandir; Ted M Dawson; Sonny Dike; Andrea L Sappington; Douglas A Kerr; Elizabeth A Jonas; Leonard K Kaczmarek; J Marie Hardwick
BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development.
Developmental cell 2003;4(4):575-85.
2003: Darren J Moore; Valina Dawson; Ted M Dawson
Role for the ubiquitin-proteasome system in Parkinson's disease and other neurodegenerative brain amyloidoses.
Neuromolecular medicine 2003;4(1-2):95-108.
2003: Ted M Dawson; Valina Dawson
Rare genetic mutations shed light on the pathogenesis of Parkinson disease.
The Journal of clinical investigation 2003;111(2):145-51.
2002: Xueying Wei; Masayuki Sasaki; Hui Huang; Valina Dawson; Ted M Dawson
The orphan nuclear receptor, steroidogenic factor 1, regulates neuronal nitric oxide synthase gene expression in pituitary gonadotropes.
Molecular endocrinology (Baltimore, Md.) 2002;16(12):2828-39.
2002: Ted M Dawson; Valina Dawson
Neuroprotective and neurorestorative strategies for Parkinson's disease.
Nature neuroscience 2002;5 Suppl():1058-61.
2002: Allen S Mandir; Cynthia M Simbulan-Rosenthal; Marc F Poitras; John R Lumpkin; Valina Dawson; Mark E Smulson; Ted M Dawson
A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism.
Journal of neurochemistry 2002;83(1):186-92.
2002: Kah Leong Lim; Valina Dawson; Ted M Dawson
The genetics of Parkinson's disease.
Current neurology and neuroscience reports 2002;2(5):439-46.
2002: Sean P Cregan; Andre Fortin; Jason G MacLaurin; Steven M Callaghan; Francesco Cecconi; Seong-Woon Yu; Ted M Dawson; Valina Dawson; David Park; Guido Kroemer; ruth slack
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death.
The Journal of cell biology 2002;158(3):507-17.
2002: Ted M Dawson; Allen S Mandir; Michael K Lee
Animal models of PD: pieces of the same puzzle?
Neuron 2002;35(2):219-22.
2002: Seong-Woon Yu; Hongmin Wang; Marc F Poitras; Carmen Coombs; William J Bowers; Howard Federoff; Guy G Poirier; Ted M Dawson; Valina Dawson
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor.
Science (New York, N.Y.) 2002;297(5579):259-63.
2002: Lan Zhou; Arthur L Burnett; Paul L Huang; Lewis C Becker; Periannan Kuppusamy; David A Kass; J Kevin Donahue; David Proud; James Sham; Ted M Dawson; Kai Y Xu
Lack of nitric oxide synthase depresses ion transporting enzyme function in cardiac muscle.
Biochemical and biophysical research communications 2002;294(5):1030-5.
2002: Michael K Lee; Wanda Stirling; Yanqun Xu; Xueying Xu; Dike Qui; Allen S Mandir; Ted M Dawson; Neal G Copeland; Nancy A Jenkins; Donald L Price
Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8968-73.
2002: Ted M Dawson; David D Ginty
CREB family transcription factors inhibit neuronal suicide.
Nature medicine 2002;8(5):450-1.
2002: Shozo Goto; Rong Xue; Nobuo Sugo; Masahiko Sawada; Kathleen K Blizzard; Marc F Poitras; David C Johns; Ted M Dawson; Valina Dawson; Barbara J Crain; Richard J Traystman; Susumu Mori; Patricia D Hurn
Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery.
Stroke; a journal of cerebral circulation 2002;33(4):1101-6.
2002: Ted M Dawson
Preconditioning-mediated neuroprotection through erythropoietin?
Lancet 2002;359(9301):96-7.
2001: Kenny K K Chung; Valina Dawson; Ted M Dawson
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders.
Trends in neurosciences 2001;24(11 Suppl):S7-14.
2001: Kenny K K Chung; Yuesheng Zhang; Kah Leong Lim; Yuji Tanaka; Hui Huang; Jianggang Gao; Christopher A Ross; Valina Dawson; Ted M Dawson
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease.
Nature medicine 2001;7(10):1144-50.
2001: X Guo; J F Dillman; Valina Dawson; Ted M Dawson
Neuroimmunophilins: novel neuroprotective and neuroregenerative targets.
Annals of neurology 2001;50(1):6-16.
2001: M Gonzalez-Zulueta; Valina Dawson; Ted M Dawson
Histochemical analysis of nitric oxide synthase by NADPH diaphorase staining.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2001;Chapter 10():Unit 10.6.
2001: J F Dillman; Valina Dawson; Ted M Dawson
Overview of the pathway and functions of nitric oxide.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2001;Chapter 10():Unit 10.1.
2001: X Guo; Valina Dawson; Ted M Dawson
Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons.
The European journal of neuroscience 2001;13(9):1683-93.
2001: K Nandagopal; Ted M Dawson; Valina Dawson
Critical role for nitric oxide signaling in cardiac and neuronal ischemic preconditioning and tolerance.
The Journal of pharmacology and experimental therapeutics 2001;297(2):474-8.
2001: Yuji Tanaka; Simone Engelender; S Igarashi; R K Rao; Tracy J Wanner; Rudolph E Tanzi; Akira Sawa; V L Dawson; Ted M Dawson; Christopher A Ross
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis.
Human molecular genetics 2001;10(9):919-26.
2001: Frederick C Nucifora; Masayuki Sasaki; Matthew F Peters; Hao Huang; Jillian K Cooper; M Yamada; H Takahashi; Shoji Tsuji; Juan C Troncoso; Valina Dawson; Ted M Dawson; Christopher A Ross
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.
Science (New York, N.Y.) 2001;291(5512):2423-8.
2001: Brigitte Wildemann; Jürgen Haas; Karoline Stingele; B Storch-HagenIocher; justin charles mcarthur; Ted M Dawson; Valina Dawson
Identification by mRNA differential display of two up-regulated genes as candidate mediators of AIDS dementia.
Molecular medicine (Cambridge, Mass.) 2001;7(3):193-9.
2001: A S Mandir; Valina Dawson; Ted M Dawson
Gene therapy to the rescue in Parkinson's disease.
Trends in pharmacological sciences 2001;22(3):103-5; discussion 105-6.
2001: Laising Yen; M Gonzalez-Zulueta; A Feldman; Y Yuan; HJ Fryer; Ted M Dawson; Valina Dawson; Robert G Kalb
Reduction of functional N-methyl-D-aspartate receptors in neurons by RNase P-mediated cleavage of the NR1 mRNA.
Journal of neurochemistry 2001;76(5):1386-94.
2001: B Aghdasi; Keqiang Ye; Adam C Resnick; A Huang; Hyo Chol Ha; X Guo; Ted M Dawson; Valina Dawson; Solomon H Snyder
FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2425-30.
2001: S Chiavegatto; Valina Dawson; Laura A Mamounas; Vassilis E Koliatsos; Ted M Dawson; R J Nelson
Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1277-81.
2001: Serge Przedborski; Ted M Dawson
The role of nitric oxide in Parkinson's disease.
Methods in molecular medicine 2001;62():113-36.
2001: Ted M Dawson; G Starkebaum; B L Wood; R F Willkens; A M Gown
Epstein-Barr virus, methotrexate, and lymphoma in patients with rheumatoid arthritis and primary Sjögren's syndrome: case series.
The Journal of rheumatology 2001;28(1):47-53.
2000: Yuesheng Zhang; Jianggang Gao; Kenny K K Chung; Hui Huang; Valina Dawson; Ted M Dawson
Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13354-9.
2000: Valina Dawson; Ted M Dawson
Neuronal ischaemic preconditioning.
Trends in pharmacological sciences 2000;21(11):423-4.
2000: Kenji Sampei; Allen S Mandir; Yoshio Asano; Philip C Wong; Richard J Traystman; Valina Dawson; Ted M Dawson; Patricia D Hurn
Stroke outcome in double-mutant antioxidant transgenic mice.
Stroke; a journal of cerebral circulation 2000;31(11):2685-91.
2000: Allen S Mandir; Marc F Poitras; A R Berliner; William Joseph Herring; DB Guastella; A Feldman; Guy G Poirier; ZQ Wang; Ted M Dawson; Valina Dawson
NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(21):8005-11.
2000: Yuesheng Zhang; Valina Dawson; Ted M Dawson
Oxidative stress and genetics in the pathogenesis of Parkinson's disease.
Neurobiology of disease 2000;7(4):240-50.
2000: Masayuki Sasaki; M Gonzalez-Zulueta; Hui Huang; William Joseph Herring; Sohyun Ahn; David D Ginty; Valina Dawson; Ted M Dawson
Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8617-22.
2000: Laura Marsh; Ted M Dawson
Treatment of early Parkinson's disease.
BMJ (Clinical research ed.) 2000;321(7252):1-2.
2000: Ted M Dawson
New animal models for Parkinson's disease.
Cell 2000;101(2):115-8.
2000: M Gonzalez-Zulueta; Andrew B Feldman; Laura J Klesse; Robert G Kalb; J F Dillman; Luis F Parada; Ted M Dawson; Valina Dawson
Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):436-41.
1999: GT Liberatore; Vernice Jackson-Lewis; S Vukosavic; Allen S Mandir; Miquel Vila; W G McAuliffe; Valina Dawson; Ted M Dawson; Serge Przedborski
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease.
Nature medicine 1999;5(12):1403-9.
1999: Ted M Dawson; G Starkebaum
Isolated central nervous system vasculitis associated with hepatitis C infection.
The Journal of rheumatology 1999;26(10):2273-6.
1999: Hye-Young Yun; Valina Dawson; Ted M Dawson
Glutamate-stimulated calcium activation of Ras/Erk pathway mediated by nitric oxide.
Diabetes research and clinical practice 1999;45(2-3):113-5.
1999: Matthew F Peters; Frederick C Nucifora; J Kushi; H C Seaman; Jillian K Cooper; William Joseph Herring; Valina Dawson; Ted M Dawson; Christopher A Ross
Nuclear targeting of mutant Huntingtin increases toxicity.
Molecular and cellular neurosciences 1999;14(2):121-8.
1999: THOMAS TUNG; Anish Bhardwaj; Valina Dawson; Ted M Dawson; Richard J Traystman; Patricia D Hurn
Neuroprotective FK506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats.
Stroke; a journal of cerebral circulation 1999;30(6):1279-85.
1999: Allen S Mandir; Serge Przedborski; Vernice Jackson-Lewis; ZQ Wang; Cynthia M Simbulan-Rosenthal; Mark E Smulson; B E Hoffman; DB Guastella; Valina Dawson; Ted M Dawson
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5774-9.
1999: Simone Engelender; Z Kaminsky; X Guo; Alan H Sharp; R K Amaravi; John Kleiderlein; Russell L Margolis; Juan C Troncoso; Anthony A Lanahan; Paul F Worley; Valina Dawson; Ted M Dawson; Christopher A Ross
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions.
Nature genetics 1999;22(1):110-4.
1999: Lance J Kriegsfeld; M J L Eliasson; Gregory Demas; Seth Blackshaw; Ted M Dawson; Randy J Nelson; Solomon H Snyder
Nocturnal motor coordination deficits in neuronal nitric oxide synthase knock-out mice.
Neuroscience 1999;89(2):311-5.
1999: D C Adamson; justin charles mcarthur; Ted M Dawson; Valina Dawson
Rate and severity of HIV-associated dementia (HAD): correlations with Gp41 and iNOS.
Molecular medicine (Cambridge, Mass.) 1999;5(2):98-109.
1999: Lance J Kriegsfeld; Gregory Demas; S E Lee; Ted M Dawson; Valina Dawson; Randy J Nelson
Circadian locomotor analysis of male mice lacking the gene for neuronal nitric oxide synthase (nNOS-/-)
Journal of biological rhythms 1999;14(1):20-7.
1999: Kai Y Xu; David L Huso; Ted M Dawson; D S Bredt; Lewis C Becker
Nitric oxide synthase in cardiac sarcoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):657-62.
1999: F Facchinetti; Masayuki Sasaki; F B Cutting; P Zhai; JE MacDonald; DW Reif; M Flint Beal; Paul L Huang; Ted M Dawson; M E Gurney; Valina Dawson
Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.
Neuroscience 1999;90(4):1483-92.
1999: D C Adamson; K L Kopnisky; Ted M Dawson; Valina Dawson
Mechanisms and structural determinants of HIV-1 coat protein, gp41-induced neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(1):64-71.
1998: F Facchinetti; Valina Dawson; Ted M Dawson
Free radicals as mediators of neuronal injury.
Cellular and molecular neurobiology 1998;18(6):667-82.
1998: Sabra L Klein; D Carnovale; Arthur L Burnett; Edward E Wallach; Howard Zacur; Julie K Crone; Valina Dawson; Randy J Nelson; Ted M Dawson
Impaired ovulation in mice with targeted deletion of the neuronal isoform of nitric oxide synthase.
Molecular medicine (Cambridge, Mass.) 1998;4(10):658-64.
1998: P Jumrussirikul; JL Dinerman; Ted M Dawson; Valina Dawson; UE Ekelund; D Georgakopoulos; Lawrence P Schramm; Hugh Calkins; Solomon H Snyder; Joshua M Hare; Ronald D Berger
Interaction between neuronal nitric oxide synthase and inhibitory G protein activity in heart rate regulation in conscious mice.
The Journal of clinical investigation 1998;102(7):1279-85.
1998: Loren D Walensky; Ted M Dawson; Joseph P Steiner; DM Sabatini; Juan D Suarez; Gary R Klinefelter; Solomon H Snyder
The 12 kD FK 506 binding protein FKBP12 is released in the male reproductive tract and stimulates sperm motility.
Molecular medicine (Cambridge, Mass.) 1998;4(8):502-14.
1998: H Y Yun; M Gonzalez-Zulueta; Valina Dawson; Ted M Dawson
Nitric oxide mediates N-methyl-D-aspartate receptor-induced activation of p21ras.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5773-8.
1998: Rachelle H Crosbie; Volker Straub; H Y Yun; JC Lee; Jill A Rafael-Fortney; Jeffrey S Chamberlain; Valina Dawson; Ted M Dawson; Kevin P Campbell
mdx muscle pathology is independent of nNOS perturbation.
Human molecular genetics 1998;7(5):823-9.
1998: Jillian K Cooper; Gabriele Schilling; Matthew F Peters; William Joseph Herring; Alan H Sharp; Z Kaminsky; J Masone; F A Khan; M Delanoy; David R Borchelt; Valina Dawson; Ted M Dawson; Christopher A Ross
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.
Human molecular genetics 1998;7(5):783-90.
1998: M Gonzalez-Zulueta; L M Ensz; Galina L Mukhina; R M Lebovitz; R M Zwacka; J F Engelhardt; L W Oberley; Valina Dawson; Ted M Dawson
Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(6):2040-55.
1998: S W Weiss; David S Albers; Michael Iadarola; Ted M Dawson; Valina Dawson; David G Standaert
NMDAR1 glutamate receptor subunit isoforms in neostriatal, neocortical, and hippocampal nitric oxide synthase neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(5):1725-34.
1998: Valina Dawson; Ted M Dawson
Nitric oxide in neurodegeneration.
Progress in brain research 1998;118():215-29.
1998: Ted M Dawson; Masayuki Sasaki; M Gonzalez-Zulueta; Valina Dawson
Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways.
Progress in brain research 1998;118():3-11.
1997: Randy J Nelson; Lance J Kriegsfeld; Valina Dawson; Ted M Dawson
Effects of nitric oxide on neuroendocrine function and behavior.
Frontiers in neuroendocrinology 1997;18(4):463-91.
1997: M J Eliasson; Kenji Sampei; Allen S Mandir; Patricia D Hurn; Richard J Traystman; J Bao; Andrew A Pieper; ZQ Wang; Ted M Dawson; Solomon H Snyder; Valina Dawson
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
Nature medicine 1997;3(10):1089-95.
1997: Ted M Dawson; G Starkebaum
Colchicine induced rhabdomyolysis.
The Journal of rheumatology 1997;24(10):2045-6.
1997: Lance J Kriegsfeld; Ted M Dawson; Valina Dawson; Randy J Nelson; Solomon H Snyder
Aggressive behavior in male mice lacking the gene for neuronal nitric oxide synthase requires testosterone.
Brain research 1997;769(1):66-70.
1997: Gregory Demas; M J L Eliasson; Ted M Dawson; Valina Dawson; Lance J Kriegsfeld; Randy J Nelson; Solomon H Snyder
Inhibition of neuronal nitric oxide synthase increases aggressive behavior in mice.
Molecular medicine (Cambridge, Mass.) 1997;3(9):610-6.
1997: Hye-Young Yun; Valina Dawson; Ted M Dawson
Nitric oxide in health and disease of the nervous system.
Molecular psychiatry 1997;2(4):300-10.
1997: Amer Samdani; C Newcamp; A Resink; F Facchinetti; B E Hoffman; Valina Dawson; Ted M Dawson
Differential susceptibility to neurotoxicity mediated by neurotrophins and neuronal nitric oxide synthase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(12):4633-41.
1997: Amer Samdani; Ted M Dawson; Valina Dawson
Nitric oxide synthase in models of focal ischemia.
Stroke; a journal of cerebral circulation 1997;28(6):1283-8.
1997: Arthur L Burnett; D C Calvin; SL Chamness; J X Liu; Randy J Nelson; Sabra L Klein; Valina Dawson; Ted M Dawson; Solomon H Snyder
Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans.
Nature medicine 1997;3(5):571-4.
1997: Joseph P Steiner; M A Connolly; Heather Valentine; Gregory S Hamilton; Ted M Dawson; Lynda D Hester; Solomon H Snyder
Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A.
Nature medicine 1997;3(4):421-8.
1997: H Togashi; Masayuki Sasaki; E Frohman; E Taira; R R Ratan; Ted M Dawson; Valina Dawson
Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2676-80.
1997: Chiye Aoki; J Rhee; M Lubin; Ted M Dawson
NMDA-R1 subunit of the cerebral cortex co-localizes with neuronal nitric oxide synthase at pre- and postsynaptic sites and in spines.
Brain research 1997;750(1-2):25-40.
1996: D C Adamson; B Wildemann; Masayuki Sasaki; Jonathan D Glass; justin charles mcarthur; V I Christov; Ted M Dawson; Valina Dawson
Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.
Science (New York, N.Y.) 1996;274(5294):1917-21.
1996: Ted M Dawson
Immunosuppressants, immunophilins, and the nervous system.
Annals of neurology 1996;40(4):559-60.
1996: Valina Dawson; Ted M Dawson
Nitric oxide actions in neurochemistry.
Neurochemistry international 1996;29(2):97-110.
1996: Edward S Ruthazer; Deda Gillespie; Ted M Dawson; Solomon H Snyder; Michael P Stryker
Inhibition of nitric oxide synthase does not prevent ocular dominance plasticity in kitten visual cortex.
The Journal of physiology 1996;494 ( Pt 2)():519-27.
1996: D C Adamson; Ted M Dawson; MARY ZINK; Janice E Clements; Valina Dawson
Neurovirulent simian immunodeficiency virus infection induces neuronal, endothelial, and glial apoptosis.
Molecular medicine (Cambridge, Mass.) 1996;2(4):417-28.
1996: Y Xia; Valina Dawson; Ted M Dawson; Solomon H Snyder; Jay L Zweier
Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6770-4.
1996: H H Lam; Daniel F Hanley; Bruce D Trapp; S Saito; Srinivasa N Raja; Ted M Dawson; H Yamaguchi
Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw.
Neuroscience letters 1996;210(3):201-4.
1996: Valina Dawson; Ted M Dawson
Nitric oxide neurotoxicity.
Journal of chemical neuroanatomy 1996;10(3-4):179-90.
1996: J Bao; Alan H Sharp; M V Wagster; Mark W Becher; Gabriele Schilling; Christopher A Ross; Valina Dawson; Ted M Dawson
Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):5037-42.
1996: Xiao-Jiang Li; Alan H Sharp; S H Li; Ted M Dawson; Solomon H Snyder; Christopher A Ross
Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4839-44.
1996: Serge Przedborski; Vernice Jackson-Lewis; R Yokoyama; T Shibata; Valina Dawson; Ted M Dawson
Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4565-71.
1996: Joseph P Steiner; Ted M Dawson; MAJID FOTUHI; Solomon H Snyder
Immunophilin regulation of neurotransmitter release.
Molecular medicine (Cambridge, Mass.) 1996;2(3):325-33.
1996: Arthur L Burnett; Randy J Nelson; D C Calvin; J X Liu; Gregory Demas; Sabra L Klein; Lance J Kriegsfeld; Valina Dawson; Ted M Dawson; Solomon H Snyder
Nitric oxide-dependent penile erection in mice lacking neuronal nitric oxide synthase.
Molecular medicine (Cambridge, Mass.) 1996;2(3):288-96.
1996: Valina Dawson; V M Kizushi; P L Huang; Solomon H Snyder; Ted M Dawson
Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(8):2479-87.
1996: CN Karson; W Sue T Griffin; Robert E Mrak; M Husain; Ted M Dawson; Solomon H Snyder; N C Moore; William Q Sturner
Nitric oxide synthase (NOS) in schizophrenia: increases in cerebellar vermis.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1996;27(3):275-84.
1996: Ryszard M Pluta; B Gregory Thompson Jr; Ted M Dawson; Solomon H Snyder; RJ Boock; Edward H Oldfield
Loss of nitric oxide synthase immunoreactivity in cerebral vasospasm.
Journal of neurosurgery 1996;84(4):648-54.
1996: Ted M Dawson
Nitric oxide: a brake for bad behavior.
Molecular psychiatry 1996;1(1):9-10.
1996: Valina Dawson; Ted M Dawson
Free radicals and neuronal cell death.
Cell death and differentiation 1996;3(1):71-8.
1996: Hye-Young Yun; Valina Dawson; Ted M Dawson
Neurobiology of nitric oxide.
Critical reviews in neurobiology 1996;10(3-4):291-316.
1996: Ted M Dawson; Valina Dawson
Generation of isoform-specific antibodies to nitric oxide synthases.
Methods in enzymology 1996;268():349-58.
1996: Ted M Dawson; Valina Dawson
Nitric oxide synthase: role as a transmitter/mediator in the brain and endocrine system.
Annual review of medicine 1996;47():219-27.
1996: Valina Dawson; Ted M Dawson
Nitric oxide in neuronal degeneration.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1996;211(1):33-40.
1995: R J Nelson; Gregory Demas; P L Huang; M C Fishman; Valina Dawson; Ted M Dawson; Solomon H Snyder
Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase.
Nature 1995;378(6555):383-6.
1995: J Hamada; Joel Greenberg; S Croul; Ted M Dawson; Martin Reivich
Effects of central inhibition of nitric oxide synthase on focal cerebral ischemia in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(5):779-86.
1995: K Irikura; Paul L Huang; J Ma; W S Lee; Turgay Dalkara; Mark C Fishman; Ted M Dawson; Solomon H Snyder; Michael A Moskowitz
Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(15):6823-7.
1995: David J Linden; Ted M Dawson; Valina Dawson
An evaluation of the nitric oxide/cGMP/cGMP-dependent protein kinase cascade in the induction of cerebellar long-term depression in culture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(7 Pt 2):5098-105.
1995: W E Lyons; Joseph P Steiner; Solomon H Snyder; Ted M Dawson
Neuronal regeneration enhances the expression of the immunophilin FKBP-12.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(4):2985-94.
1995: Ted M Dawson; Valina Dawson
ADP-ribosylation as a mechanism for the action of nitric oxide in the nervous system.
New horizons (Baltimore, Md.) 1995;3(1):85-92.
1995: Valina Dawson; Ted M Dawson
Physiological and toxicological actions of nitric oxide in the central nervous system.
Advances in pharmacology (San Diego, Calif.) 1995;34():323-42.
1995: Ted M Dawson; K Hung; Valina Dawson; Joseph P Steiner; Solomon H Snyder
Neuroprotective effects of gangliosides may involve inhibition of nitric oxide synthase.
Annals of neurology 1995;37(1):115-8.
1994: David R Lynch; Ted M Dawson
Secondary mechanisms in neuronal trauma.
Current opinion in neurology 1994;7(6):510-6.
1994: Ted M Dawson; Valina Dawson; Solomon H Snyder
Molecular mechanisms of nitric oxide actions in the brain.
Annals of the New York Academy of Sciences 1994;738():76-85.
1994: A G Kovách; Zsolt Lohinai; J Marczis; I Balla; Ted M Dawson; Solomon H Snyder
The effect of hemorrhagic hypotension and retransfusion and 7-nitro-indazole on rCBF, NOS catalytic activity, and cortical NO content in the cat.
Annals of the New York Academy of Sciences 1994;738():348-68.
1994: Valina Dawson; H P Brahmbhatt; Jessica Mong; Ted M Dawson
Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures.
Neuropharmacology 1994;33(11):1425-30.
1994: J L Dinerman; Joseph P Steiner; Ted M Dawson; Valina Dawson; Solomon H Snyder
Cyclic nucleotide dependent phosphorylation of neuronal nitric oxide synthase inhibits catalytic activity.
Neuropharmacology 1994;33(11):1245-51.
1994: Lars Bö; Ted M Dawson; S Wesselingh; Sverre Mörk; S Choi; P A Kong; Daniel F Hanley; Bruce D Trapp
Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains.
Annals of neurology 1994;36(5):778-86.
1994: C Aoki; C Venkatesan; C G Go; Jessica Mong; Ted M Dawson
Cellular and subcellular localization of NMDA-R1 subunit immunoreactivity in the visual cortex of adult and neonatal rats.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(9):5202-22.
1994: Ted M Dawson; Solomon H Snyder
Gases as biological messengers: nitric oxide and carbon monoxide in the brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(9):5147-59.
1994: Ted M Dawson; Joseph P Steiner; W E Lyons; MAJID FOTUHI; Mary E Blue; Solomon H Snyder
The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin.
Neuroscience 1994;62(2):569-80.
1994: W Wu; FJ Liuzzi; F P Schinco; A S Depto; Y Li; Jessica Mong; Ted M Dawson; Solomon H Snyder
Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury.
Neuroscience 1994;61(4):719-26.
1994: A J Roskams; D S Bredt; Ted M Dawson; Gabriele V Ronnett
Nitric oxide mediates the formation of synaptic connections in developing and regenerating olfactory receptor neurons.
Neuron 1994;13(2):289-99.
1994: Thomas J O'Dell; P L Huang; Ted M Dawson; J L Dinerman; Solomon H Snyder; Eric R Kandel; M C Fishman
Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS.
Science (New York, N.Y.) 1994;265(5171):542-6.
1994: Valina Dawson; C Y Hsu; T H Liu; Ted M Dawson; J K Wamsley
Receptor alterations in subcortical structures after bilateral middle cerebral artery infarction of the cerebral cortex.
Experimental neurology 1994;128(1):88-96.
1994: J L Dinerman; Ted M Dawson; M J Schell; Adele M Snowman; Solomon H Snyder
Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4214-8.
1994: W E Lyons; Edwin George; Ted M Dawson; Joseph P Steiner; Solomon H Snyder
Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3191-5.
1994: S Saito; G J Kidd; Bruce D Trapp; Ted M Dawson; D S Bredt; David Allen Wilson; Richard J Traystman; Solomon H Snyder; Daniel F Hanley
Rat spinal cord neurons contain nitric oxide synthase.
Neuroscience 1994;59(2):447-56.
1994: Jin Zhang; Valina Dawson; Ted M Dawson; Solomon H Snyder
Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity.
Science (New York, N.Y.) 1994;263(5147):687-9.
1994: Ted M Dawson; Jin Zhang; Valina Dawson; Solomon H Snyder
Nitric oxide: cellular regulation and neuronal injury.
Progress in brain research 1994;103():365-9.
1994: Ted M Dawson; Valina Dawson
gp120 neurotoxicity in primary cortical cultures.
Advances in neuroimmunology 1994;4(3):167-73.
1993: P L Huang; Ted M Dawson; D S Bredt; Solomon H Snyder; Mark C Fishman
Targeted disruption of the neuronal nitric oxide synthase gene.
Cell 1993;75(7):1273-86.
1993: R Yamamoto; D S Bredt; Ted M Dawson; Solomon H Snyder; Richard A Stone
Enhanced expression of nitric oxide synthase by rat retina following pterygopalatine parasympathetic denervation.
Brain research 1993;631(1):83-8.
1993: Maureen W McEnery; Ted M Dawson; A Verma; D Gurley; Marco Colombini; Solomon H Snyder
Mitochondrial voltage-dependent anion channel. Immunochemical and immunohistochemical characterization in rat brain.
The Journal of biological chemistry 1993;268(31):23289-96.
1993: D B Hirsch; Joseph P Steiner; Ted M Dawson; Alex Mammen; E Hayek; Solomon H Snyder
Neurotransmitter release regulated by nitric oxide in PC-12 cells and brain synaptosomes.
Current biology : CB 1993;3(11):749-54.
1993: Ted M Dawson; Joseph P Steiner; Valina Dawson; J L Dinerman; George R. Uhl; Solomon H Snyder
Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):9808-12.
1993: MAJID FOTUHI; Ted M Dawson; Alan H Sharp; Lee J Martin; Ann M Graybiel; Solomon H Snyder
Phosphoinositide second messenger system is enriched in striosomes: immunohistochemical demonstration of inositol 1,4,5-trisphosphate receptors and phospholipase C beta and gamma in primate basal ganglia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(8):3300-8.
1993: Alan H Sharp; P S McPherson; Ted M Dawson; C Aoki; K P Campbell; Solomon H Snyder
Differential immunohistochemical localization of inositol 1,4,5-trisphosphate- and ryanodine-sensitive Ca2+ release channels in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(7):3051-63.
1993: Valina Dawson; Ted M Dawson; D A Bartley; George R. Uhl; Solomon H Snyder
Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(6):2651-61.
1993: MAJID FOTUHI; Alan H Sharp; C E Glatt; PAUL HWANG; M von Krosigk; Solomon H Snyder; Ted M Dawson
Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(5):2001-12.
1993: Valina Dawson; Ted M Dawson; George R. Uhl; Solomon H Snyder
Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3256-9.
1993: Alan H Sharp; Ted M Dawson; Christopher A Ross; MAJID FOTUHI; R J Mourey; Solomon H Snyder
Inositol 1,4,5-trisphosphate receptors: immunohistochemical localization to discrete areas of rat central nervous system.
Neuroscience 1993;53(4):927-42.
1993: Ted M Dawson; J L Arriza; D E Jaworsky; F F Borisy; H Attramadal; R J Lefkowitz; Gabriele V Ronnett
Beta-adrenergic receptor kinase-2 and beta-arrestin-2 as mediators of odorant-induced desensitization.
Science (New York, N.Y.) 1993;259(5096):825-9.
1993: K Nozaki; Michael A Moskowitz; K I Maynard; N Koketsu; Ted M Dawson; D S Bredt; Solomon H Snyder
Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(1):70-9.
1993: Ted M Dawson; Valina Dawson; Solomon H Snyder
Nitric oxide as a mediator of neurotoxicity.
NIDA research monograph 1993;136():258-71; discussion 271-3.
1992: Bradley T Hyman; K Marzloff; J J Wenniger; Ted M Dawson; D S Bredt; Solomon H Snyder
Relative sparing of nitric oxide synthase-containing neurons in the hippocampal formation in Alzheimer's disease.
Annals of neurology 1992;32(6):818-20.
1992: Ted M Dawson
Esthetic controls for anterior restorations.
Dental economics - oral hygiene 1992;82(11):114-5.
1992: J L Arriza; Ted M Dawson; Richard B Simerly; Lee J Martin; Marc G Caron; Solomon H Snyder; R J Lefkowitz
The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(10):4045-55.
1992: R J Mourey; Ted M Dawson; Roxanne K Barrow; A E Enna; Solomon H Snyder
[3H]noscapine binding sites in brain: relationship to indoleamines and the phosphoinositide and adenylyl cyclase messenger systems.
Molecular pharmacology 1992;42(4):619-26.
1992: H Attramadal; J L Arriza; C Aoki; Ted M Dawson; J Codina; Madan M Kwatra; Solomon H Snyder; Marc G Caron; R J Lefkowitz
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.
The Journal of biological chemistry 1992;267(25):17882-90.
1992: Ted M Dawson; Valina Dawson; Solomon H Snyder
A novel neuronal messenger molecule in brain: the free radical, nitric oxide.
Annals of neurology 1992;32(3):297-311.
1992: Joseph P Steiner; Ted M Dawson; MAJID FOTUHI; C E Glatt; Adele M Snowman; N Cohen; Solomon H Snyder
High brain densities of the immunophilin FKBP colocalized with calcineurin.
Nature 1992;358(6387):584-7.
1992: David R Lynch; Ted M Dawson; EC Raps; Steven L Galetta
Risk factors for the neurologic complications associated with aortic aneurysms.
Archives of neurology 1992;49(3):284-8.
1991: Ted M Dawson; E Lavi; EC Raps; Herbert I Goldberg
Thrombotic microangiopathy isolated to the central nervous system.
Annals of neurology 1991;30(6):843-6.
1991: D S Bredt; C E Glatt; PAUL HWANG; MAJID FOTUHI; Ted M Dawson; Solomon H Snyder
Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase.
Neuron 1991;7(4):615-24.
1991: Ted M Dawson; D S Bredt; MAJID FOTUHI; PAUL HWANG; Solomon H Snyder
Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7797-801.
1991: Valina Dawson; Ted M Dawson; Edythe D London; D S Bredt; Solomon H Snyder
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6368-71.
1991: Ted M Dawson; Valina Dawson; F H Gage; Lisa J Fisher; M A Hunt; J K Wamsley
Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra.
Experimental neurology 1991;111(3):282-92.
1991: Ted M Dawson; Valina Dawson; F H Gage; Lisa J Fisher; M A Hunt; J K Wamsley
Downregulation of muscarinic receptors in the rat caudate-putamen after lesioning of the ipsilateral nigrostriatal dopamine pathway with 6-hydroxydopamine (6-OHDA): normalization by fetal mesencephalic transplants.
Brain research 1991;540(1-2):145-52.
1991: J K Wamsley; Ted M Dawson; Valina Dawson; M A Hunt; Lisa J Fisher; F H Gage
Reversal of nigrostriatal-lesion-induced receptor alterations by grafting of fetal mesencephalic dopaminergic neurons.
Advances in experimental medicine and biology 1991;287():221-35.
1990: Valina Dawson; Ted M Dawson; J K Wamsley
Muscarinic and dopaminergic receptor subtypes on striatal cholinergic interneurons.
Brain research bulletin 1990;25(6):903-12.
1990: Francis M Filloux; M V Wagster; Susan E Folstein; Donald L Price; J C Hedreen; Ted M Dawson; J K Wamsley
Nigral dopamine type-1 receptors are reduced in Huntington's disease: a postmortem autoradiographic study using [3H]SCH 23390 and correlation with [3H]forskolin binding.
Experimental neurology 1990;110(2):219-27.
1989: J K Wamsley; D R Gehlert; F M Filloux; Ted M Dawson
Comparison of the distribution of D-1 and D-2 dopamine receptors in the rat brain.
Journal of chemical neuroanatomy 1989;2(3):119-37.
1988: Ted M Dawson; P Barone; A Sidhu; J K Wamsley; Thomas N Chase
The D1 dopamine receptor in the rat brain: quantitative autoradiographic localization using an iodinated ligand.
Neuroscience 1988;26(1):83-100.
1988: Francis M Filloux; Ted M Dawson; J K Wamsley
Localization of nigrostriatal dopamine receptor subtypes and adenylate cyclase.
Brain research bulletin 1988;20(4):447-59.
1988: Valina Dawson; Ted M Dawson; Francis M Filloux; J K Wamsley
Evidence for dopamine D-2 receptors on cholinergic interneurons in the rat caudate-putamen.
Life sciences 1988;42(20):1933-9.
1988: William Byerley; E J McConnell; R T McCabe; Ted M Dawson; B I Grosser; J K Wamsley
Decreased beta-adrenergic receptors in rat brain after chronic administration of the selective serotonin uptake inhibitor fluoxetine.
Psychopharmacology 1988;94(1):141-3.
1987: R T McCabe; Glen R Hanson; Ted M Dawson; J K Wamsley; James W Gibb
Methamphetamine-induced reduction in D1 and D2 dopamine receptors as evidenced by autoradiography: comparison with tyrosine hydroxylase activity.
Neuroscience 1987;23(1):253-61.
1987: William Byerley; E J McConnell; R T McCabe; Ted M Dawson; B I Grosser; J K Wamsley
Chronic administration of sertraline, a selective serotonin uptake inhibitor, decreased the density of beta-adrenergic receptors in rat frontoparietal cortex.
Brain research 1987;421(1-2):377-81.
1987: Ted M Dawson; R T McCabe; S S Stensaas; J K Wamsley
Autoradiographic evidence of [3H]SCH 23390 binding sites in human prefrontal cortex (Brodmann's area 9).
Journal of neurochemistry 1987;49(3):789-96.
1987: F M Filloux; J K Wamsley; Ted M Dawson
Dopamine D-2 auto- and postsynaptic receptors in the nigrostriatal system of the rat brain: localization by quantitative autoradiography with [3H]sulpiride.
European journal of pharmacology 1987;138(1):61-8.
1987: F M Filloux; J K Wamsley; Ted M Dawson
Presynaptic and postsynaptic D1 dopamine receptors in the nigrostriatal system of the rat brain: a quantitative autoradiographic study using the selective D1 antagonist [3H]SCH 23390.
Brain research 1987;408(1-2):205-9.
1987: J K Wamsley; William Byerley; R T McCabe; E J McConnell; Ted M Dawson; B I Grosser
Receptor alterations associated with serotonergic agents: an autoradiographic analysis.
The Journal of clinical psychiatry 1987;48 Suppl():19-25.
1987: D R Gehlert; Ted M Dawson; F M Filloux; E Sanna; I Hanbauer; J K Wamsley
Evidence that [3H]forskolin binding in the substantia nigra is intrinsic to a striatal-nigral projection: an autoradiographic study of rat brain.
Neuroscience letters 1987;73(2):114-8.
1986: Ted M Dawson; P Barone; A Sidhu; J K Wamsley; Thomas N Chase
Quantitative autoradiographic localization of D-1 dopamine receptors in the rat brain: use of the iodinated ligand [125I]SCH 23982.
Neuroscience letters 1986;68(3):261-6.
1986: Ted M Dawson; D R Gehlert; R T McCabe; A Barnett; J K Wamsley
D-1 dopamine receptors in the rat brain: a quantitative autoradiographic analysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(8):2352-65.
1986: Ted M Dawson; D R Gehlert; J K Wamsley
Quantitative autoradiographic localization of the dopamine transport complex in the rat brain: use of a highly selective radioligand: [3H]GBR 12935.
European journal of pharmacology 1986;126(1-2):171-3.
1986: Ted M Dawson; D R Gehlert; J K Wamsley
Quantitative autoradiographic localization of central dopamine D-1 and D-2 receptors.
Advances in experimental medicine and biology 1986;204():93-118.
1985: D R Gehlert; Ted M Dawson; Henry I Yamamura; J K Wamsley
Quantitative autoradiography of [3H]forskolin binding sites in the rat brain.
Brain research 1985;361(1-2):351-60.
1985: A S Unis; Ted M Dawson; D R Gehlert; J K Wamsley
Autoradiographic localization of [3H]methylphenidate binding sites in rat brain.
European journal of pharmacology 1985;113(1):155-7.
1985: Ted M Dawson; D R Gehlert; E W Snowhill; J K Wamsley
Quantitative autoradiographic evidence for axonal transport of imipramine receptors in the central nervous system of the rat.
Neuroscience letters 1985;55(3):261-6.
1985: Ted M Dawson; D R Gehlert; Henry I Yamamura; A Barnett; J K Wamsley
D-1 dopamine receptors in the rat brain: autoradiographic localization using [3H]SCH 23390.
European journal of pharmacology 1985;108(3):323-5.
1984: D R Gehlert; Ted M Dawson; Henry I Yamamura; J K Wamsley
Localization of [3H]forskolin binding sites in the rat brain using quantitative autoradiography.
European journal of pharmacology 1984;106(1):223-5.
1983: Ted M Dawson; J K Wamsley
Autoradiographic localization of [3H]-imipramine binding sites: association with serotonergic neurons.
Brain research bulletin 1983;11(3):325-34.