FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Pamela Zeitlin

Research Profile

Disorders

Cystic Fibrosis

Chemicals & Drugs

Physiology

Mutation

Anatomy

Procedures

Genetic Therapy

Living Beings

Co-author Network

Publications

TOP 3
Eric S Schiffhauer; Neeraj Vij; Doug Walker; Po Wei Kang; Olga Kovbasnjuk; Seakwoo Lee; Pamela L Zeitlin
Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia.
Catherine E Jozwik; Harvey B Pollard; Meera Srivastava; Thomas Darling; Ofer Eidelman; QingYuan Fan; Pamela L Zeitlin
Antibody microarrays: analysis of cystic fibrosis.
Jung Soo Suk; Benjamin Tang; Kanika Trehan; Pamela L Zeitlin; Nicholas J Boylan; Michael P Boyle; Mark J Cooper; Samuel Lai; Jung-Ming G Lin; Craig S Schneider; Justin Hanes
N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Pamela Zeitlin (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Eric S Schiffhauer; Neeraj Vij; Doug Walker; Po Wei Kang; Olga Kovbasnjuk; Seakwoo Lee; Pamela L Zeitlin
Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia.
American journal of physiology. Lung cellular and molecular physiology 2013;304(5):L324-31.
2012: Catherine E Jozwik; Harvey B Pollard; Meera Srivastava; Thomas Darling; Ofer Eidelman; QingYuan Fan; Pamela L Zeitlin
Antibody microarrays: analysis of cystic fibrosis.
Methods in molecular biology (Clifton, N.J.) 2012;823():179-200.
2011: Jung Soo Suk; Benjamin Tang; Kanika Trehan; Pamela L Zeitlin; Nicholas J Boylan; Michael P Boyle; Mark J Cooper; Samuel Lai; Jung-Ming G Lin; Craig S Schneider; Justin Hanes
N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(11):1981-9.
2011: Lara C Kovell; Jiangxia Wang; Pamela L Zeitlin; Stacey L Ishman; Emily Frances Boss
Cystic fibrosis and sinusitis in children: outcomes and socioeconomic status.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2011;145(1):146-53.
2010: Mark J Henderson; Om Vir Singh; Pamela L Zeitlin
Applications of proteomic technologies for understanding the premature proteolysis of CFTR.
Expert review of proteomics 2010;7(4):473-86.
2010: Mark J Henderson; Neeraj Vij; Pamela L Zeitlin
Ubiquitin C-terminal hydrolase-L1 protects cystic fibrosis transmembrane conductance regulator from early stages of proteasomal degradation.
The Journal of biological chemistry 2010;285(15):11314-25.
2010: Sharon A McGrath-Morrow; J Michael Collaco; Thomas O Crawford; Kathryn Carson; Maureen A Lefton-Greif; Pamela L Zeitlin; Howard M Lederman
Elevated serum IL-8 levels in ataxia telangiectasia.
The Journal of pediatrics 2010;156(4):682-4.e1.
2010: Deanna M Green; Amanda R Leonard; SHRUTI PARANJAPE; Beryl J Rosenstein; Pamela L Zeitlin; Peter J Mogayzel
Transient effectiveness of vitamin D2 therapy in pediatric cystic fibrosis patients.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 2010;9(2):143-9.
2010: Thomas Ferkol; Pamela L Zeitlin; Steven Abman; Carol J Blaisdell; Hugh O'Brodovich
NHLBI training workshop report: The vanishing pediatric pulmonary investigator and recommendations for recovery.
Pediatric pulmonology 2010;45(1):25-33.
2010: Amanda Leonard; Erin Davis; Beryl J Rosenstein; Pamela L Zeitlin; SHRUTI PARANJAPE; Donna Peeler; Cynthia Maynard; Peter J Mogayzel
Description of a standardized nutrition classification plan and its relation to nutritional outcomes in children with cystic fibrosis.
Journal of pediatric psychology 2010;35(1):6-13.
2009: Benjamin Tang; Michelle Dawson; Samuel Lai; Ying-Ying Wang; Jung Soo Suk; Ming Yang; Pamela L Zeitlin; Michael P Boyle; Jie Fu; Justin Hanes
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19268-73.
2009: Thomas Ferkol; Pamela L Zeitlin; Steven Abman; Carol J Blaisdell; Hugh O'Brodovich
NHLBI training workshop report: the vanishing pediatric pulmonary investigator and recommendations for recovery.
Lung 2009;187(6):367-74.
2009: Pamela L Zeitlin
Pseudomonas aeruginosa: can studies in engineered cells tell us why is it such a problem in people with cystic fibrosis? Focus on "Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa".
American journal of physiology. Cell physiology 2009;297(2):C235-7.
2009: Jung Soo Suk; Samuel Lai; Ying-Ying Wang; Laura M Ensign; Pamela L Zeitlin; Michael P Boyle; Justin Hanes
The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.
Biomaterials 2009;30(13):2591-7.
2009: Om Vir Singh; Myron Yaster; Ji-Tian Xu; Yun Guan; XIAOWEI GUAN; Arun M Dharmarajan; Srinivasa N Raja; Pamela L Zeitlin; YUANXIANG TAO
Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury.
Proteomics 2009;9(5):1241-53.
2009: Neeraj Vij; Steven Mazur; Pamela L Zeitlin
CFTR is a negative regulator of NFkappaB mediated innate immune response.
PloS one 2009;4(2):e4664.
2009: Lihua Liang; Kelvin MacDonald; Erik M Schwiebert; Pamela L Zeitlin; William B Guggino
Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway.
American journal of physiology. Cell physiology 2009;296(1):C131-41.
2008: Pamela L Zeitlin
Cystic fibrosis and estrogens: a perfect storm.
The Journal of clinical investigation 2008;118(12):3841-4.
2008: SHRUTI PARANJAPE; Pamela L Zeitlin
Atypical cystic fibrosis and CFTR-related diseases.
Clinical reviews in allergy & immunology 2008;35(3):116-23.
2008: Kelvin MacDonald; Karen R McKenzie; Mark J Henderson; Charles E Hawkins; Neeraj Vij; Pamela L Zeitlin
Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice.
American journal of physiology. Lung cellular and molecular physiology 2008;295(5):L933-40.
2008: Deanna Green; Kathryn Carson; Amanda Leonard; J Erin Davis; Beryl J Rosenstein; Pamela L Zeitlin; Peter J Mogayzel
Current treatment recommendations for correcting vitamin D deficiency in pediatric patients with cystic fibrosis are inadequate.
The Journal of pediatrics 2008;153(4):554-9.
2008: Om Vir Singh; Harvey B Pollard; Pamela L Zeitlin
Chemical rescue of deltaF508-CFTR mimics genetic repair in cystic fibrosis bronchial epithelial cells.
Molecular & cellular proteomics : MCP 2008;7(6):1099-110.
2008: Kara L Murray; Carlton K K Lee; Peter J Mogayzel; Pamela L Zeitlin; Beryl J Rosenstein
Dietary supplement use in pediatric patients with cystic fibrosis.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 2008;65(6):562-5.
2008: Neeraj Vij; Martha O Amoako; Steven Mazur; Pamela L Zeitlin
CHOP transcription factor mediates IL-8 signaling in cystic fibrosis bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2008;38(2):176-84.
2008: Laurie Conklin; Pamela L Zeitlin; C Cuffari
Cystic fibrosis presenting as recurrent pancreatitis in a young child with a normal sweat test and pancreas divisum: a case report.
Journal of medical case reports 2008;2():176.
2008: Sharon A McGrath-Morrow; Maureen A Lefton-Greif; Karen Rosquist; Thomas O Crawford; Amber Kelly; Pamela L Zeitlin; Kathryn Carson; Howard M Lederman
Pulmonary function in adolescents with ataxia telangiectasia.
Pediatric pulmonology 2008;43(1):59-66.
2007: STEPHANIE HSU; Joshua D Groman; Christian A Merlo; Kathleen Naughton; Pamela L Zeitlin; Emily L Germain-Lee; Michael P Boyle; Garry R Cutting
Patients with mutations in Gsalpha have reduced activation of a downstream target in epithelial tissues due to haploinsufficiency.
The Journal of clinical endocrinology and metabolism 2007;92(10):3941-8.
2007: Harvey B Pollard; Meera Srivastava; Ofer Eidelman; Catherine Jozwik; Stephen W Rothwell; Gregory P Mueller; David M Jacobowitz; Thomas Darling; William B Guggino; Jerry Wright; Pamela L Zeitlin; Cloud P Paweletz
Protein microarray platforms for clinical proteomics.
Proteomics. Clinical applications 2007;1(9):934-52.
2007: Richard B Moss; Carlos Milla; John Colombo; Frank J Accurso; Pamela L Zeitlin; John P Clancy; L Terry Spencer; Joseph M Pilewski; David A Waltz; Henry L Dorkin; Thomas Ferkol; Mark Pian; Bonnie W Ramsey; Barbara J Carter; Dana B Martin; Alison E Heald
Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial.
Human gene therapy 2007;18(8):726-32.
2007: Ronald L Gibson; Julia Emerson; Nicole Mayer-Hamblett; Jane L Burns; Sharon McNamara; Frank J Accurso; Michael W Konstan; Barbara A Chatfield; George Retsch-Bogart; David A Waltz; James Acton; Pamela L Zeitlin; Peter Hiatt; Richard Moss; Judy Williams; Bonnie W Ramsey
Duration of treatment effect after tobramycin solution for inhalation in young children with cystic fibrosis.
Pediatric pulmonology 2007;42(7):610-23.
2007: John P Clancy; Steven M Rowe; Zsuzsa Bebok; Moira L Aitken; Ron Gibson; Pamela L Zeitlin; Pierre Berclaz; Richard Moss; Michael Knowles; Robert A Oster; Nicole Mayer-Hamblett; Bonnie W Ramsey
No detectable improvements in cystic fibrosis transmembrane conductance regulator by nasal aminoglycosides in patients with cystic fibrosis with stop mutations.
American journal of respiratory cell and molecular biology 2007;37(1):57-66.
2007: Pamela L Zeitlin
Emerging drug treatments for cystic fibrosis.
Expert opinion on emerging drugs 2007;12(2):329-36.
2007: Carlton K K Lee; Michael P Boyle; Marie Diener-West; Lois Brass-Ernst; Michelle Noschese; Pamela L Zeitlin
Levofloxacin pharmacokinetics in adult cystic fibrosis.
Chest 2007;131(3):796-802.
2007: Kitti Buranawuti; Michael P Boyle; Suzanne Cheng; Lori L Steiner; Kathryn McDougal; MARGARET D FALLIN; Christian A Merlo; Pamela L Zeitlin; Beryl J Rosenstein; Peter J Mogayzel; Xinjing Wang; Garry R Cutting
Variants in mannose-binding lectin and tumour necrosis factor alpha affect survival in cystic fibrosis.
Journal of medical genetics 2007;44(3):209-14.
2007: Kelvin MacDonald; Karen R McKenzie; Pamela L Zeitlin
Cystic fibrosis transmembrane regulator protein mutations: 'class' opportunity for novel drug innovation.
Paediatric drugs 2007;9(1):1-10.
2006: Pamela L Zeitlin
Is it go or NO go for S-nitrosylation modification-based therapies of cystic fibrosis transmembrane regulator trafficking?
Molecular pharmacology 2006;70(4):1155-8.
2006: Harvey B Pollard; Ofer Eidelman; Catherine Jozwik; Wei Huang; Meera Srivastava; Xiao-Duo Ji; Brighid McGowan; Christine Formas Norris; Tsuyoshi Todo; Thomas Darling; Peter J Mogayzel; Pamela L Zeitlin; Jerry Wright; William B Guggino; Eleanore Metcalf; William J Driscoll; Greg Mueller; Cloud Paweletz; David M Jacobowitz
De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells.
Molecular & cellular proteomics : MCP 2006;5(9):1628-37.
2006: Jerry Wright; Christian A Merlo; Jeffrey B Reynolds; Pamela L Zeitlin; Joe G. N. Garcia; William B Guggino; Michael P Boyle
Respiratory epithelial gene expression in patients with mild and severe cystic fibrosis lung disease.
American journal of respiratory cell and molecular biology 2006;35(3):327-36.
2006: Neeraj Vij; Shengyun Fang; Pamela L Zeitlin
Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels: therapeutic implications.
The Journal of biological chemistry 2006;281(25):17369-78.
2006: Neeraj Vij; Pamela L Zeitlin
Regulation of the ClC-2 lung epithelial chloride channel by glycosylation of SP1.
American journal of respiratory cell and molecular biology 2006;34(6):754-9.
2006: Meera Srivastava; Ofer Eidelman; Catherine Jozwik; Cloud Paweletz; Wei Huang; Pamela L Zeitlin; Harvey B Pollard
Serum proteomic signature for cystic fibrosis using an antibody microarray platform.
Molecular genetics and metabolism 2006;87(4):303-10.
2006: Om Vir Singh; Neeraj Vij; Peter J Mogayzel; Catherine Jozwik; Harvey B Pollard; Pamela L Zeitlin
Pharmacoproteomics of 4-phenylbutyrate-treated IB3-1 cystic fibrosis bronchial epithelial cells.
Journal of proteome research 2006;5(3):562-71.
2006: Omotola Uwaifo; Penelope Bamford; Pamela L Zeitlin; Carol J Blaisdell
Acidic pH hyperpolarizes nasal potential difference.
Pediatric pulmonology 2006;41(2):151-7.
2006: Michael P Boyle; Raymond A Enke; Jeffrey B Reynolds; Peter J Mogayzel; William B Guggino; Pamela L Zeitlin
Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia.
Virology journal 2006;3():29.
2005: Beth L Laube; David E Geller; Ta-Chun Lin; Richard N. Dalby; Marie Diener-West; Pamela L Zeitlin
Positive expiratory pressure changes aerosol distribution in patients with cystic fibrosis.
Respiratory care 2005;50(11):1438-44.
2005: Terence R Flotte; Erik M Schwiebert; Pamela L Zeitlin; Barbara J Carter; William B Guggino
Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy.
Human gene therapy 2005;16(8):921-8.
2005: Robin Deterding; George Retsch-Bogart; Laura J H Milgram; Ron Gibson; Cori Daines; Pamela L Zeitlin; Carlos Milla; Bruce Marshall; Lisa M LaVange; Jean Engels; Dave Mathews; Joann Gorden; Amy Schaberg; Judy Williams; Bonnie W Ramsey
Safety and tolerability of denufosol tetrasodium inhalation solution, a novel P2Y2 receptor agonist: results of a phase 1/phase 2 multicenter study in mild to moderate cystic fibrosis.
Pediatric pulmonology 2005;39(4):339-48.
2005: Richard B Moss; Nicole Mayer-Hamblett; Jeffrey S Wagener; Cori Daines; Kathryn Hale; Richard Ahrens; Ronald L Gibson; Paula Anderson; George Retsch-Bogart; Samya Z Nasr; Imre Noth; David A Waltz; Pamela L Zeitlin; Bonnie W Ramsey; Karen M Starko
Randomized, double-blind, placebo-controlled, dose-escalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease.
Pediatric pulmonology 2005;39(3):209-18.
2005: Hui Bi Cao; Anan Wang; Bernard Martin; David R Koehler; Pamela L Zeitlin; A Keith Tanawell; Jim Hu
Down-regulation of IL-8 expression in human airway epithelial cells through helper-dependent adenoviral-mediated RNA interference.
Cell research 2005;15(2):111-9.
2004: Joshua D Groman; William E Bolger; Lois Brass-Ernst; Milan Macek Jr.; Pamela L Zeitlin; Garry R Cutting
Recurrent and destructive nasal polyposis in 2 siblings: a possible case of Woakes' syndrome.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2004;131(6):1009-11.
2004: Gerry A Croteau; Dana B Martin; Janice E Camp; Michael G Yost; Carol Conrad; Pamela L Zeitlin; Alison E Heald
Evaluation of exposure and health care worker response to nebulized administration of tgAAVCF to patients with cystic fibrosis.
The Annals of occupational hygiene 2004;48(8):673-81.
2004: Meerana Lim; Karen McKenzie; Alexandra D Floyd; Edwin Kwon; Pamela L Zeitlin
Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids.
American journal of respiratory cell and molecular biology 2004;31(3):351-7.
2004: Pamela L Zeitlin
Can curcumin cure cystic fibrosis?
The New England journal of medicine 2004;351(6):606-8.
2004: Thomas A Standaert; Louis Boitano; Julia Emerson; Laura J H Milgram; Michael W Konstan; Janice Hunter; Pierre-Yves Berclaz; Lois Brass; Pamela L Zeitlin; Keith B Hammond; Zoe Davies; Carla Foy; Peadar G Noone; Michael Knowles
Standardized procedure for measurement of nasal potential difference: an outcome measure in multicenter cystic fibrosis clinical trials.
Pediatric pulmonology 2004;37(5):385-92.
2004: Richard B Moss; David Rodman; L Terry Spencer; Moira L Aitken; Pamela L Zeitlin; David A Waltz; Carlos Milla; Alan S Brody; John P Clancy; Bonnie W Ramsey; Nicole Hamblett; Alison E Heald
Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial.
Chest 2004;125(2):509-21.
2004: Jerry Wright; Pamela L Zeitlin; Liudmila Cebotaru; Sandra E Guggino; William B Guggino
Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins.
Physiological genomics 2004;16(2):204-11.
2004: Pamela L Zeitlin; Michael P Boyle; William B Guggino; Luis Molina
A phase I trial of intranasal Moli1901 for cystic fibrosis.
Chest 2004;125(1):143-9.
2003: Claudia L Ordoñez; Noreen R Henig; Nicole Mayer-Hamblett; Frank J Accurso; Jane L Burns; James F Chmiel; Cori L Daines; Ronald L Gibson; Sharon McNamara; George Retsch-Bogart; Pamela L Zeitlin; Moira L Aitken
Inflammatory and microbiologic markers in induced sputum after intravenous antibiotics in cystic fibrosis.
American journal of respiratory and critical care medicine 2003;168(12):1471-5.
2003: Pamela L Zeitlin
Emerging drug treatments for cystic fibrosis.
Expert opinion on emerging drugs 2003;8(2):523-35.
2003: Pamela L Zeitlin; Dorothy Berlin Gail; Susan Banks-Schlegel
Protein processing and degradation in pulmonary health and disease.
American journal of respiratory cell and molecular biology 2003;29(5):642-5.
2003: Kathryn W Holmes; Russell Hales; Shijian Chu; Micah J Maxwell; Peter J Mogayzel; Pamela L Zeitlin
Modulation of Sp1 and Sp3 in lung epithelial cells regulates ClC-2 chloride channel expression.
American journal of respiratory cell and molecular biology 2003;29(4):499-505.
2003: Michael P Boyle; Marie Diener-West; Laura J H Milgram; Michael Knowles; Carla Foy; Pamela L Zeitlin; Thomas A Standaert
A multicenter study of the effect of solution temperature on nasal potential difference measurements.
Chest 2003;124(2):482-9.
2003: Terence R Flotte; Pamela L Zeitlin; Thomas C Reynolds; Alison E Heald; Patty Pedersen; Suzanne Beck; Carol K Conrad; Lois Brass-Ernst; Margaret Humphries; Kevin Sullivan; Randall Wetzel; George Taylor; Barbara J Carter; William B Guggino
Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study.
Human gene therapy 2003;14(11):1079-88.
2003: Ronald L Gibson; Julia Emerson; Sharon McNamara; Jane L Burns; Margaret Rosenfeld; Ann Yunker; Nicole Hamblett; Frank J Accurso; Mark Dovey; Peter Hiatt; Michael W Konstan; Richard Moss; George Retsch-Bogart; Jeffrey S Wagener; David A Waltz; Robert W Wilmott; Pamela L Zeitlin; Bonnie W Ramsey
Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis.
American journal of respiratory and critical care medicine 2003;167(6):841-9.
2003: Michael P Boyle; Raymond A Enke; Peter J Mogayzel; William B Guggino; Dana B Martin; Shikha Agarwal; Pamela L Zeitlin
Effect of adeno-associated virus-specific immunoglobulin G in human amniotic fluid on gene transfer.
Human gene therapy 2003;14(4):365-73.
2002: Kristina Powell; Pamela L Zeitlin
Therapeutic approaches to repair defects in deltaF508 CFTR folding and cellular targeting.
Advanced drug delivery reviews 2002;54(11):1395-408.
2002: Joshua D Groman; Michelle E Meyer; Robert W Wilmott; Pamela L Zeitlin; Garry R Cutting
Variant cystic fibrosis phenotypes in the absence of CFTR mutations.
The New England journal of medicine 2002;347(6):401-7.
2002: Peter J Mogayzel; Muneer Esmail; Traci L Wagner; Pamela L Zeitlin; Melissa Ashlock
cis-Acting elements within CFTR 5'-flanking DNA are not sufficient to decrease gene expression in response to phorbol ester.
Biochimica et biophysica acta 2002;1576(3):306-15.
2002: Pamela L Zeitlin; Marie Diener-West; Ronald C Rubenstein; Michael P Boyle; Carlton K K Lee; Lois Brass-Ernst
Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(1):119-26.
2002: Rebecca D Edmonds; Ian V Silva; William B Guggino; Robert B Butler; Pamela L Zeitlin; Carol J Blaisdell
ClC-5: ontogeny of an alternative chloride channel in respiratory epithelia.
American journal of physiology. Lung cellular and molecular physiology 2002;282(3):L501-7.
2001: Pamela L Zeitlin
Advances in the diagnosis of cystic fibrosis in infants.
The Journal of pediatrics 2001;139(3):345-6.
2001: Michael P Boyle; Raymond A Enke; Robert J Adams; William B Guggino; Pamela L Zeitlin
In utero AAV-mediated gene transfer to rabbit pulmonary epithelium.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(2):115-21.
2001: Peadar G Noone; Nicole Hamblett; Frank J Accurso; Moira L Aitken; Michael P Boyle; Mark Dovey; Ron Gibson; C Johnson; D Kellerman; Michael W Konstan; Laura J H Milgram; J Mundahl; G Retsch-Bogort; D Rodman; J Williams-Warren; Robert W Wilmott; Pamela L Zeitlin; Bonnie W Ramsey
Safety of aerosolized INS 365 in patients with mild to moderate cystic fibrosis: results of a phase I multi-center study.
Pediatric pulmonology 2001;32(2):122-8.
2001: Lee R Choo-Kang; Pamela L Zeitlin
Induction of HSP70 promotes DeltaF508 CFTR trafficking.
American journal of physiology. Lung cellular and molecular physiology 2001;281(1):L58-68.
2001: M Lim; Pamela L Zeitlin
Therapeutic strategies to correct malfunction of CFTR.
Paediatric respiratory reviews 2001;2(2):159-64.
2000: A Callen; Marie Diener-West; Pamela L Zeitlin; R C Rubenstein
A simplified cyclic adenosine monophosphate-mediated sweat rate test for quantitative measure of cystic fibrosis transmembrane regulator (CFTR) function.
The Journal of pediatrics 2000;137(6):849-55.
2000: Lee R Choo-Kang; Pamela L Zeitlin
Type I, II, III, IV, and V cystic fibrosis transmembrane conductance regulator defects and opportunities for therapy.
Current opinion in pulmonary medicine 2000;6(6):521-9.
2000: Xinjing Wang; B Moylan; Donald A Leopold; JEAN KIM; R C Rubenstein; Alkis Togias; David Proud; Pamela L Zeitlin; Garry R Cutting
Mutation in the gene responsible for cystic fibrosis and predisposition to chronic rhinosinusitis in the general population.
JAMA : the journal of the American Medical Association 2000;284(14):1814-9.
2000: Beth L Laube; R Jashnani; Richard N. Dalby; Pamela L Zeitlin
Targeting aerosol deposition in patients with cystic fibrosis: effects of alterations in particle size and inspiratory flow rate.
Chest 2000;118(4):1069-76.
2000: Carol J Blaisdell; R D Edmonds; X T Wang; Sandra E Guggino; Pamela L Zeitlin
pH-regulated chloride secretion in fetal lung epithelia.
American journal of physiology. Lung cellular and molecular physiology 2000;278(6):L1248-55.
2000: Pamela L Zeitlin
Pharmacologic restoration of delta F508 CFTR-mediated chloride current.
Kidney international 2000;57(3):832-7.
2000: Ronald C Rubenstein; Pamela L Zeitlin
Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR.
American journal of physiology. Cell physiology 2000;278(2):C259-67.
2000: Pamela L Zeitlin
Future pharmacological treatment of cystic fibrosis.
Respiration; international review of thoracic diseases 2000;67(4):351-7.
2000: Pamela L Zeitlin
Cystic fibrosis gene therapy trials and tribulations.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(1):5-6.
1999: S Chu; Carol J Blaisdell; M Z Liu; Pamela L Zeitlin
Perinatal regulation of the ClC-2 chloride channel in lung is mediated by Sp1 and Sp3.
The American journal of physiology 1999;276(4 Pt 1):L614-24.
1999: Carol J Blaisdell; J P Pellettieri; Ceila Loughlin; S Chu; Pamela L Zeitlin
Keratinocyte growth factor stimulates CLC-2 expression in primary fetal rat distal lung epithelial cells.
American journal of respiratory cell and molecular biology 1999;20(4):842-7.
1999: Pamela L Zeitlin
Novel pharmacologic therapies for cystic fibrosis.
The Journal of clinical investigation 1999;103(4):447-52.
1998: Pamela L Zeitlin
Therapies directed at the basic defect in cystic fibrosis.
Clinics in chest medicine 1998;19(3):515-25, vi-vii.
1998: R C Rubenstein; Pamela L Zeitlin
Use of protein repair therapy in the treatment of cystic fibrosis.
Current opinion in pediatrics 1998;10(3):250-5.
1998: Erik M Schwiebert; L P Cid-Soto; D Stafford; M Carter; Carol J Blaisdell; Pamela L Zeitlin; William B Guggino; Garry R Cutting
Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3879-84.
1998: R C Rubenstein; Pamela L Zeitlin
A pilot clinical trial of oral sodium 4-phenylbutyrate (Buphenyl) in deltaF508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR function.
American journal of respiratory and critical care medicine 1998;157(2):484-90.
1998: Beryl J Rosenstein; Pamela L Zeitlin
Cystic fibrosis.
Lancet 1998;351(9098):277-82.
1997: R C Rubenstein; M E Egan; Pamela L Zeitlin
In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.
The Journal of clinical investigation 1997;100(10):2457-65.
1997: S Chu; Pamela L Zeitlin
Alternative mRNA splice variants of the rat ClC-2 chloride channel gene are expressed in lung: genomic sequence and organization of ClC-2.
Nucleic acids research 1997;25(20):4153-9.
1997: R C Rubenstein; U McVeigh; Terence R Flotte; William B Guggino; Pamela L Zeitlin
CFTR gene transduction in neonatal rabbits using an adeno-associated virus (AAV) vector.
Gene therapy 1997;4(5):384-92.
1996: C B Murray; S Chu; Pamela L Zeitlin
Gestational and tissue-specific regulation of C1C-2 chloride channel expression.
The American journal of physiology 1996;271(5 Pt 1):L829-37.
1996: S Chu; C B Murray; M M Liu; Pamela L Zeitlin
A short CIC-2 mRNA transcript is produced by exon skipping.
Nucleic acids research 1996;24(17):3453-7.
1995: Beryl J Rosenstein; Pamela L Zeitlin
Prognosis in cystic fibrosis.
Current opinion in pulmonary medicine 1995;1(6):444-9.
1995: Pamela L Zeitlin; S Chu; C Conrad; U McVeigh; K Ferguson; Terence R Flotte; William B Guggino
Alveolar stem cell transduction by an adeno-associated viral vector.
Gene therapy 1995;2(9):623-31.
1995: C Guay-Broder; Kenneth Alan Jacobson; S Barnoy; Ioav Cabantchik; William B Guggino; Pamela L Zeitlin; R James Turner; L Vergara; O Eidelman; Harvey B Pollard
A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine selectively activates chloride efflux from human epithelial and mouse fibroblast cell lines expressing the cystic fibrosis transmembrane regulator delta F508 mutation.
Biochemistry 1995;34(28):9079-87.
1995: C B Murray; Marcelo Marcos Morales; Terence R Flotte; Sharon A McGrath-Morrow; William B Guggino; Pamela L Zeitlin
CIC-2: a developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth.
American journal of respiratory cell and molecular biology 1995;12(6):597-604.
1994: Terence R Flotte; S A Afione; Pamela L Zeitlin
Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration.
American journal of respiratory cell and molecular biology 1994;11(5):517-21.
1993: Elizabeth J. Perlman; Howard M Lederman; G A Taylor; M B Fasano; Gerald M Loughlin; Pamela L Zeitlin
"Bronchitis" obliterans and prolonged transient hypogammaglobulinemia in a child.
Pediatric pulmonology 1993;16(6):375-9.
1993: Terence R Flotte; S A Afione; C Conrad; Sharon A McGrath-Morrow; R Solow; H Oka; Pamela L Zeitlin; William B Guggino; Barbara J Carter
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10613-7.
1993: Karl Kunzelmann; Erik M Schwiebert; Pamela L Zeitlin; W L Kuo; B A Stanton; Dieter C Gruenert
An immortalized cystic fibrosis tracheal epithelial cell line homozygous for the delta F508 CFTR mutation.
American journal of respiratory cell and molecular biology 1993;8(5):522-9.
1993: Terence R Flotte; S A Afione; R Solow; M L Drumm; D Markakis; William B Guggino; Pamela L Zeitlin; Barbara J Carter
Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter.
The Journal of biological chemistry 1993;268(5):3781-90.
1993: Sharon A McGrath-Morrow; A Basu; Pamela L Zeitlin
Cystic fibrosis gene and protein expression during fetal lung development.
American journal of respiratory cell and molecular biology 1993;8(2):201-8.
1992: Marie E Egan; M H Wagner; Pamela L Zeitlin; William B Guggino
Modulation of ion transport in cultured rabbit tracheal epithelium by lipoxygenase metabolites.
American journal of respiratory cell and molecular biology 1992;7(5):500-6.
1992: Terence R Flotte; R Solow; Roland A Owens; S Afione; Pamela L Zeitlin; Barbara J Carter
Gene expression from adeno-associated virus vectors in airway epithelial cells.
American journal of respiratory cell and molecular biology 1992;7(3):349-56.
1992: M Egan; T Flotte; S Afione; R Solow; Pamela L Zeitlin; Barbara J Carter; William B Guggino
Defective regulation of outwardly rectifying Cl- channels by protein kinase A corrected by insertion of CFTR.
Nature 1992;358(6387):581-4.
1992: J L Wiebke; C Montrose-Rafizadeh; Pamela L Zeitlin; William B Guggino
Effect of hypoxia on endothelin-1 production by pulmonary vascular endothelial cells.
Biochimica et biophysica acta 1992;1134(2):105-11.
1992: Pamela L Zeitlin; I Crawford; L Lu; S Woel; M E Cohen; Mark Donowitz; MH Montrose; Ada Hamosh; Garry R Cutting; Dieter C Gruenert
CFTR protein expression in primary and cultured epithelia.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):344-7.
1991: Ada Hamosh; B C Trapnell; Pamela L Zeitlin; C Montrose-Rafizadeh; Beryl J Rosenstein; R G Crystal; Garry R Cutting
Severe deficiency of cystic fibrosis transmembrane conductance regulator messenger RNA carrying nonsense mutations R553X and W1316X in respiratory epithelial cells of patients with cystic fibrosis.
The Journal of clinical investigation 1991;88(6):1880-5.
1991: I Crawford; Peter C Maloney; Pamela L Zeitlin; William B Guggino; S C Hyde; H Turley; K C Gatter; A Harris; C F Higgins
Immunocytochemical localization of the cystic fibrosis gene product CFTR.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):9262-6.
1991: B C Trapnell; Pamela L Zeitlin; C S Chu; K Yoshimura; H Nakamura; William B Guggino; J Bargon; T C Banks; W Dalemans; A Pavirani
Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester.
The Journal of biological chemistry 1991;266(16):10319-23.
1991: Pamela L Zeitlin; L Lu; J Rhim; Garry R Cutting; Gail Stetten; K A Kieffer; R Craig; William B Guggino
A cystic fibrosis bronchial epithelial cell line: immortalization by adeno-12-SV40 infection.
American journal of respiratory cell and molecular biology 1991;4(4):313-9.
1989: L Lu; Pamela L Zeitlin; William B Guggino; Ruth W Craig
Gene transfer by lipofection in rabbit and human secretory epithelial cells.
Pflügers Archiv : European journal of physiology 1989;415(2):198-203.
1989: T C Hwang; L Lu; Pamela L Zeitlin; Dieter C Gruenert; Richard Huganir; William B Guggino
Cl- channels in CF: lack of activation by protein kinase C and cAMP-dependent protein kinase.
Science (New York, N.Y.) 1989;244(4910):1351-3.
1989: Pamela L Zeitlin; M Wagner; D Markakis; Gerald M Loughlin; William B Guggino
Steroid hormones: modulators of Na+ absorption and Cl- secretion in cultured tracheal epithelia.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2502-5.
1988: Pamela L Zeitlin; Gerald M Loughlin; William B Guggino
Ion transport in cultured fetal and adult rabbit tracheal epithelia.
The American journal of physiology 1988;254(5 Pt 1):C691-8.
1982: Pamela L Zeitlin; Ann L Hubbard
Cell surface distribution and intracellular fate of asialoglycoproteins: a morphological and biochemical study of isolated rat hepatocytes and monolayer cultures.
The Journal of cell biology 1982;92(3):634-47.
1974: Pamela L Zeitlin; E Segovia; J J McNamara
Critical evaluation of the hematoxylin-basic fuchsin picric acid stain as an indication of early muscle ischemia.
Hawaii medical journal 1974;33(2):65-9.