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Bharathi Gorantla

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Phenomena

Physiology

Procedures

Disorders

Glioma

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Publications

TOP 3
Sreelatha Gopinath; Bharathi Gorantla; Meena Gujrati; Ramarao Malla; Kiranmai Alapati; Dzung Hong Dinh; Jasti S Rao
Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression.
Kompella Amala; A K S Bhujanga Rao; Christopher Gondi; Bharathi Gorantla; Jasti S Rao
Design, synthesis and preclinical evaluation of NRC-AN-019.
G S Sailaja; Kiran Kumar Velpula; Praveen Bhoopathi; Chandramu Chetty; Venkateswara Rao Gogineni; Christopher Gondi; Bharathi Gorantla; Jasti S Rao
The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma.

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All Publications

2013: Sreelatha Gopinath; Bharathi Gorantla; Meena Gujrati; Ramarao Malla; Kiranmai Alapati; Dzung Hong Dinh; Jasti S Rao
Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression.
Carcinogenesis 2013;34(3):550-9.
2013: Kompella Amala; A K S Bhujanga Rao; Christopher Gondi; Bharathi Gorantla; Jasti S Rao
Design, synthesis and preclinical evaluation of NRC-AN-019.
International journal of oncology 2013;42(1):168-78.
2013: G S Sailaja; Kiran Kumar Velpula; Praveen Bhoopathi; Chandramu Chetty; Venkateswara Rao Gogineni; Christopher Gondi; Bharathi Gorantla; Jasti S Rao
The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma.
International journal of oncology 2013;42(1):188-96.
2013: Bharathi Gorantla; G S Sailaja; Praveen Bhoopathi; Chandramu Chetty; Venkateswara Rao Gogineni; Christopher Gondi; Jasti S Rao
Notch signaling regulates tumor-induced angiogenesis in SPARC-overexpressed neuroblastoma.
Angiogenesis 2013;16(1):85-100.
2012: Swapna Asuthkar; Chandramu Chetty; Bharathi Gorantla; Kiran Kumar Velpula; Jasti S Rao
Epigenetic regulation of miRNA-211 by MMP-9 governs glioma cell apoptosis, chemosensitivity and radiosensitivity.
Oncotarget 2012;3(11):1439-54.
2012: Kiran Kumar Velpula; Swapna Asuthkar; Venkata Ramesh Dasari; Bharathi Gorantla; Andrew Joseph Tsung
EGFR and c-Met Cross Talk in Glioblastoma and Its Regulation by Human Cord Blood Stem Cells.
Translational oncology 2012;5(5):379-92.
2012: Swapna Asuthkar; Christopher Gondi; Bharathi Gorantla; Arun Kumar Nalla; Kiran Kumar Velpula; Jasti Sambasiva Rao
Urokinase-type plasminogen activator receptor (uPAR)-mediated regulation of WNT/β-catenin signaling is enhanced in irradiated medulloblastoma cells.
The Journal of biological chemistry 2012;287(24):20576-89.
2012: Rama Rao Malla; Kiranmai Alapati; Christopher Gondi; Sreelatha Gopinath; Bharathi Gorantla; Jasti Sambasiva Rao
uPAR and cathepsin B inhibition enhanced radiation-induced apoptosis in gliomainitiating cells.
Neuro-oncology 2012;14(6):745-60.
2012: Praveen Bhoopathi; Christopher Gondi; Bharathi Gorantla; Meena Gujrati; Jeffrey David Klopfenstein; G S Sailaja; Jasti Sambasiva Rao
SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT.
PloS one 2012;7(5):e36093.
2011: Christopher Gondi; Bharathi Gorantla; K V Jogi; Ajit Junnarkar; Praveen C Myneni; M U R Naidu; K Amala; A K S Bhujanga Rao; G Venkat Ramana; Jasti Sambasiva Rao
Antitumor activity of NRC-AN-019 in a pre-clinical breast cancer model.
International journal of oncology 2011;39(3):641-8.
2011: Bharathi Gorantla; Swapna Asuthkar; Jasti Sambasiva Rao; Jitendra Patel; Christopher Gondi
Suppression of the uPAR-uPA system retards angiogenesis, invasion, and in vivo tumor development in pancreatic cancer cells.
Molecular cancer research : MCR 2011;9(4):377-89.
2011: Divya Kesanakurti; Chandramu Chetty; Praveen Bhoopathi; Seeta Sajani Lakka; Bharathi Gorantla; Andrew Joseph Tsung; Jasti Sambasiva Rao
Suppression of MMP-2 attenuates TNF-α induced NF-κB activation and leads to JNK mediated cell death in glioma.
PloS one 2011;6(5):e19341.
2010: Arun Kumar Nalla; Bharathi Gorantla; Christopher Gondi; Seeta Sajani Lakka; Jasti Sambasiva Rao
Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells.
Cancer gene therapy 2010;17(9):599-613.
2010: Sai Murali Krishna Pulukuri; Bharathi Gorantla; Venkata Ramesh Dasari; Christopher Gondi; Jasti Sambasiva Rao
Epigenetic upregulation of urokinase plasminogen activator promotes the tropism of mesenchymal stem cells for tumor cells.
Molecular cancer research : MCR 2010;8(8):1074-83.
2010: Christopher Gondi; Krishna Kumar Veeravalli; Bharathi Gorantla; Dzung Hong Dinh; Daniel Fassett; Jeffrey David Klopfenstein; Meena Gujrati; Jasti Sambasiva Rao
Human umbilical cord blood stem cells show PDGF-D-dependent glioma cell tropism in vitro and in vivo.
Neuro-oncology 2010;12(5):453-65.
2010: Christopher Gondi; Venkateswara Rao Gogineni; Chandramu Chetty; Venkata R Dasari; Bharathi Gorantla; Meena Gujrati; Dzung Hong Dinh; Jasti Sambasiva Rao
Induction of apoptosis in glioma cells requires cell-to-cell contact with human umbilical cord blood stem cells.
International journal of oncology 2010;36(5):1165-73.
2010: Venkateswara Rao Gogineni; Arun Kumar Nalla; Reshu Gupta; Bharathi Gorantla; Meena Gujrati; Dzung Hong Dinh; Jasti Sambasiva Rao
Radiation-inducible silencing of uPA and uPAR in vitro and in vivo in meningioma.
International journal of oncology 2010;36(4):809-16.
2009: Sai Murali Krishna Pulukuri; Bharathi Gorantla; J A Knost; Jasti Sambasiva Rao
Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer.
Oncogene 2009;28(31):2829-38.
2007: Sai Murali Krishna Pulukuri; Bharathi Gorantla; Jasti Sambasiva Rao
Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator.
The Journal of biological chemistry 2007;282(49):35594-603.

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