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Barbara Casadei

Research Profile

Disorders

Chemicals & Drugs

Physiology

Baroreflexes

Living Beings

Anatomy

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Publications

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Ricardo Carnicer; Nicholas J Alp; Jennifer K Bendall; Keith M Channon; Mark Crabtree; Ashley B Hale; Gregory B S Lim; Xing Liu; Svetlana Reilly; Silvia Suffredini; Nicoletta C Surdo; Mei Hua Zhang; Barbara Casadei
Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation.
Sandra Marisa Oliveira; Katalin Pinter; Houman Ashrafian; Mohamed Bellahcene; David Carling; Barbara Casadei; Joanna K Davies; Ying Ge; Henrik Isackson; Raquel Sancho Solis; Jeffery W Walker; Hugh Watkins; Arash Yavari; Yin-Hua Zhang; Charles Redwood
AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes.
David Adlam; Barbara Casadei; Stephanie J Cragg; E J F Danson; Joseph P de Bono; Gillian Douglas; Neil Herring; Katie A Jennings; Dan Li; Cheih-Ju Lu; David J Paterson; Amy Tatham; Keith M Channon
Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.

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All Publications

2012: Ricardo Carnicer; Nicholas J Alp; Jennifer K Bendall; Keith M Channon; Mark Crabtree; Ashley B Hale; Gregory B S Lim; Xing Liu; Svetlana Reilly; Silvia Suffredini; Nicoletta C Surdo; Mei Hua Zhang; Barbara Casadei
Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation.
Circulation research 2012;111(6):718-27.
2012: Sandra Marisa Oliveira; Katalin Pinter; Houman Ashrafian; Mohamed Bellahcene; David Carling; Barbara Casadei; Joanna K Davies; Ying Ge; Henrik Isackson; Raquel Sancho Solis; Jeffery W Walker; Hugh Watkins; Arash Yavari; Yin-Hua Zhang; Charles Redwood
AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes.
Circulation research 2012;110(9):1192-201.
2012: David Adlam; Barbara Casadei; Stephanie J Cragg; E J F Danson; Joseph P de Bono; Gillian Douglas; Neil Herring; Katie A Jennings; Dan Li; Cheih-Ju Lu; David J Paterson; Amy Tatham; Keith M Channon
Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
Cardiovascular research 2012;93(4):694-701.
2011: Charalambos Antoniades; Alexios S Antonopoulos; Constantinos Bakogiannis; Jennifer Bendall; Barbara Casadei; Michael Demosthenous; Tomasz Guzik; Ashley Hale; Paul Leeson; Kyriakoula Marinou; Andreas Paschalis; Costas Psarros; Christodoulos I Stefanadis; Dimitris Tousoulis; Costas Triantafyllou; Mei-Hua Zhang; Keith M Channon
Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling.
Circulation 2011;124(3):335-45.
2010: L Li; Steven A Niederer; W Idigo; Y H Zhang; Pawel Swietach; Barbara Casadei; Nicolas P Smith
A mathematical model of the murine ventricular myocyte: a data-driven biophysically based approach applied to mice overexpressing the canine NCX isoform.
American journal of physiology. Heart and circulatory physiology 2010;299(4):H1045-63.
2010: Charalambos Antoniades; Constantinos Bakogiannis; Dimitris Tousoulis; Svetlana Reilly; Mei-Hua Zhang; Andreas Paschalis; Alexios S Antonopoulos; Michael Demosthenous; Antigoni Miliou; Costas Psarros; Kyriakoula Marinou; Nikolaos Sfyras; George Economopoulos; Barbara Casadei; Keith M Channon; Christodoulos I Stefanadis
Preoperative atorvastatin treatment in CABG patients rapidly improves vein graft redox state by inhibition of Rac1 and NADPH-oxidase activity.
Circulation 2010;122(11 Suppl):S66-73.
2009: Charalambos Antoniades; Tim Van-Assche; Cheerag Shirodaria; Jonathan Diesch; Alexios S Antonopoulos; Justin Lee; Colin Cunnington; Dimitris Tousoulis; Christodoulos I Stefanadis; Barbara Casadei; David P Taggart; Keith M Channon; Paul Leeson
Preoperative sCD40L levels predict risk of atrial fibrillation after off-pump coronary artery bypass graft surgery.
Circulation 2009;120(11 Suppl):S170-6.
2009: Yin Hua Zhang; Lewis Dingle; Rachel Hall; Barbara Casadei
The role of nitric oxide and reactive oxygen species in the positive inotropic response to mechanical stretch in the mammalian myocardium.
Biochimica et biophysica acta 2009;1787(7):811-7.
2008: Barbara Casadei
Beta 3-adrenoceptors modulate left ventricular relaxation in the rat heart via the NO-cGMP-PKG pathway.
Acta physiologica (Oxford, England) 2008;193(3):203.
2008: Yin Hua Zhang; Mei Hua Zhang; Claire E Sears; Krzysztof Emanuel; Charles Redwood; Ali El-Armouche; Evangelia G Kranias; Barbara Casadei
Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice.
Circulation research 2008;102(2):242-9.
2008: Gregory Lim; Luigi A Venetucci; David A Eisner; Barbara Casadei
Does nitric oxide modulate cardiac ryanodine receptor function? Implications for excitation-contraction coupling.
Cardiovascular research 2008;77(2):256-64.
2008: Young M Kim; Hassan Kattach; Chandana Ratnatunga; Ravi Pillai; Keith M Channon; Barbara Casadei
Association of atrial nicotinamide adenine dinucleotide phosphate oxidase activity with the development of atrial fibrillation after cardiac surgery.
Journal of the American College of Cardiology 2008;51(1):68-74.
2006: Barbara Casadei
The emerging role of neuronal nitric oxide synthase in the regulation of myocardial function.
Experimental physiology 2006;91(6):943-55.
2006: Sarah R Martin; Krzysztof Emanuel; Claire E Sears; Yin-Hua Zhang; Barbara Casadei
Are myocardial eNOS and nNOS involved in the beta-adrenergic and muscarinic regulation of inotropy? A systematic investigation.
Cardiovascular research 2006;70(1):97-106.
2005: Dana Dawson; Craig A Lygate; Mei Hua Zhang; Karen Hulbert; Stefan Neubauer; Barbara Casadei
nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction.
Circulation 2005;112(24):3729-37.
2005: Young M Kim; Tomasz Guzik; Yin Hua Zhang; Mei Hua Zhang; Hassan Kattach; Chandana Ratnatunga; Ravi Pillai; Keith M Channon; Barbara Casadei
A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation.
Circulation research 2005;97(7):629-36.
2005: E J F Danson; Y H Zhang; Claire E Sears; A R Edwards; Barbara Casadei; David J Paterson
Disruption of inhibitory G-proteins mediates a reduction in atrial beta-adrenergic signaling by enhancing eNOS expression.
Cardiovascular research 2005;67(4):613-23.
2005: Steffen E Petersen; Joseph B Selvanayagam; Jane M Francis; Saul G Myerson; Frank Wiesmann; Matthew D Robson; Ingegerd Ostman-Smith; Barbara Casadei; Hugh Watkins; Stefan Neubauer
Differentiation of athlete's heart from pathological forms of cardiac hypertrophy by means of geometric indices derived from cardiovascular magnetic resonance.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2005;7(3):551-8.
2005: Barbara Casadei; Hala Abuzeid
Is there a strong rationale for deferring elective surgery in patients with poorly controlled hypertension?
Journal of hypertension 2005;23(1):19-22.
2004: Claire E Sears; Euan Ashley; Barbara Casadei
Nitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1446):1021-44.
2004: Jeffrey P Khoo; Nicholas J Alp; Jennifer K Bendall; Seinosuke Kawashima; Mitsuhiro Yokoyama; Yin-Hua Zhang; Barbara Casadei; Keith M Channon
EPR quantification of vascular nitric oxide production in genetically modified mouse models.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2004;10(3):156-61.
2003: Barbara Casadei; Claire E Sears
Nitric-oxide-mediated regulation of cardiac contractility and stretch responses.
Progress in biophysics and molecular biology 2003;82(1-3):67-80.
2003: Claire E Sears; Simon M Bryant; Euan Ashley; Craig A Lygate; Stevan Rakovic; Helen L Wallis; Stefan Neubauer; Derek A Terrar; Barbara Casadei
Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling.
Circulation research 2003;92(5):e52-9.
2002: Euan Ashley; Claire E Sears; Simon M Bryant; Hugh Watkins; Barbara Casadei
Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes.
Circulation 2002;105(25):3011-6.
2002: Attila Kardos; Gusztáv Watterich; Barbara Casadei; László Rudas
Baroreflex sensitivity: population values.
Acta cardiologica 2002;57(1):41-2.
2001: Barbara Casadei
Vagal control of myocardial contractility in humans.
Experimental physiology 2001;86(6):817-23.
2001: Simon M Bryant; Claire E Sears; Lauren Rigg; Derek A Terrar; Barbara Casadei
Nitric oxide does not modulate the hyperpolarization-activated current, I(f), in ventricular myocytes from spontaneously hypertensive rats.
Cardiovascular research 2001;51(1):51-8.
2001: Judith M Thornton; Abe Guz; K Murphy; A R Griffith; D L Pedersen; Attila Kardos; A Leff; L Adams; Barbara Casadei; David J Paterson
Identification of higher brain centres that may encode the cardiorespiratory response to exercise in humans.
The Journal of physiology 2001;533(Pt 3):823-36.
2001: Attila Kardos; G Watterich; R de Menezes; Miklós Csanády; Barbara Casadei; László Rudas
Determinants of spontaneous baroreflex sensitivity in a healthy working population.
Hypertension 2001;37(3):911-6.
2001: M Elsheikh; Barbara Casadei; Gerard S Conway; J A H Wass
Hypertension is a major risk factor for aortic root dilatation in women with Turner's syndrome.
Clinical endocrinology 2001;54(1):69-73.
2001: M El-Omar; Attila Kardos; Barbara Casadei
Mechanisms of respiratory sinus arrhythmia in patients with mild heart failure.
American journal of physiology. Heart and circulatory physiology 2001;280(1):H125-31.
2000: P Musialek; Lauren Rigg; Derek A Terrar; David J Paterson; Barbara Casadei
Role of cGMP-inhibited phosphodiesterase and sarcoplasmic calcium in mediating the increase in basal heart rate with nitric oxide donors.
Journal of molecular and cellular cardiology 2000;32(10):1831-40.
2000: Bernard Keavney; R Bird; A Caiazza; Barbara Casadei; J Conway
Measurement of blood pressure using the auscultatory and oscillometric methods in the same cuff deflation: validation and field trial of the A&D TM2421 monitor.
Journal of human hypertension 2000;14(9):573-9.
2000: P Musialek; Barbara Casadei
Nitrovasodilators and heart rate: more than the arterial baroreflex.
Cardiovascular research 2000;47(2):404-5.
2000: Ravi M Mohan; Julia K Choate; Simon Golding; Neil Herring; Barbara Casadei; David J Paterson
Peripheral pre-synaptic pathway reduces the heart rate response to sympathetic activation following exercise training: role of NO.
Cardiovascular research 2000;47(1):90-8.
2000: Attila Kardos; Doris J Taylor; C Thompson; Peter Styles; Linda Hands; Jack Collin; Barbara Casadei
Sympathetic denervation of the upper limb improves forearm exercise performance and skeletal muscle bioenergetics.
Circulation 2000;101(23):2716-20.
2000: M Elsheikh; R Bird; Barbara Casadei; Gerard S Conway; J A H Wass
The effect of hormone replacement therapy on cardiovascular hemodynamics in women with Turner's syndrome.
The Journal of clinical endocrinology and metabolism 2000;85(2):614-8.
2000: Barbara Casadei; David J Paterson
Should we still use nitrovasodilators to test baroreflex sensitivity?
Journal of hypertension 2000;18(1):3-6.
1999: P Musialek; David J Paterson; Barbara Casadei
Changes in extracellular pH mediate the chronotropic responses to L-arginine.
Cardiovascular research 1999;43(3):712-20.
1999: N Hogan; Barbara Casadei; David J Paterson
Nitric oxide donors can increase heart rate independent of autonomic activation.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;87(1):97-103.
1999: N Hogan; Attila Kardos; David J Paterson; Barbara Casadei
Effect of exogenous nitric oxide on baroreflex function in humans.
The American journal of physiology 1999;277(1 Pt 2):H221-7.
1999: Attila Kardos; Barbara Casadei
Hormone replacement therapy and ischaemic heart disease among postmenopausal women.
Journal of cardiovascular risk 1999;6(2):105-12.
1998: G Heinert; Barbara Casadei; David J Paterson
Hypercapnic cerebral blood flow in spontaneously hypertensive rats.
Journal of hypertension 1998;16(10):1491-8.
1998: A Zawadzka; R Bird; Barbara Casadei; J Conway
Audit of ambulatory blood pressure monitoring in the diagnosis and management of hypertension in practice.
Journal of human hypertension 1998;12(4):249-52.
1998: Attila Kardos; V Long; J Bryant; J Singh; Peter Sleight; Barbara Casadei
Lipophilic versus hydrophilic beta(1) blockers and the cardiac sympatho-vagal balance during stress and daily activity in patients after acute myocardial infarction.
Heart (British Cardiac Society) 1998;79(2):153-60.
1998: Judith M Thornton; D L Pederson; Attila Kardos; Abe Guz; Barbara Casadei; David J Paterson
Ventilatory response to imagination of exercise and altered perception of exercise load under hypnosis.
Advances in experimental medicine and biology 1998;450():195-7.
1997: T E Meyer; Barbara Casadei; Gerard P Aurigemma; William H Gaasch
Which indexes of filling behavior should be used to characterize left ventricular diastolic function when changes in heart rate and atrioventricular delay occur?
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 1997;10(7):689-98.
1997: P Musialek; Ming Lei; H F Brown; David J Paterson; Barbara Casadei
Nitric oxide can increase heart rate by stimulating the hyperpolarization-activated inward current, I(f).
Circulation research 1997;81(1):60-8.
1996: Barbara Casadei; J Moon; J Johnston; A Caiazza; Peter Sleight
Is respiratory sinus arrhythmia a good index of cardiac vagal tone in exercise?
Journal of applied physiology (Bethesda, Md. : 1985) 1996;81(2):556-64.
1996: Barbara Casadei; J Conway; C Forfar; Peter Sleight
Effect of low doses of scopolamine on RR interval variability, baroreflex sensitivity, and exercise performance in patients with chronic heart failure.
Heart (British Cardiac Society) 1996;75(3):274-80.
1996: C Dudley; Bernard Keavney; Barbara Casadei; J Conway; R Bird; Peter J Ratcliffe
Prediction of patient responses to antihypertensive drugs using genetic polymorphisms: investigation of renin-angiotensin system genes.
Journal of hypertension 1996;14(2):259-62.
1995: Barbara Casadei; S Cochrane; J Johnston; J Conway; Peter Sleight
Pitfalls in the interpretation of spectral analysis of the heart rate variability during exercise in humans.
Acta physiologica Scandinavica 1995;153(2):125-31.
1994: S Attwood; R Bird; K Burch; Barbara Casadei; A Coats; J Conway; M Dawes; D Ebbs; Andrew Farmer; J Robinson
Within-patient correlation between the antihypertensive effects of atenolol, lisinopril and nifedipine.
Journal of hypertension 1994;12(9):1053-60.
1993: Barbara Casadei; A Pipilis; F Sessa; J Conway; Peter Sleight
Low doses of scopolamine increase cardiac vagal tone in the acute phase of myocardial infarction.
Circulation 1993;88(2):353-7.
1992: P Davey; T Meyer; A Coats; Stamatis Adamopoulos; Barbara Casadei; J Conway; P Sleight
Ventilation in chronic heart failure: effects of physical training.
British heart journal 1992;68(5):473-7.
1992: Alberto Radaelli; M Piepoli; Stamatis Adamopoulos; A Pipilis; S J Clark; Barbara Casadei; T E Meyer; Andrew J S Coats
Effects of mild physical activity, atenolol and the combination on ambulatory blood pressure in hypertensive subjects.
Journal of hypertension 1992;10(10):1279-82.
1992: Barbara Casadei; T E Meyer; Andrew J S Coats; J Conway; P Sleight
Baroreflex control of stroke volume in man: an effect mediated by the vagus.
The Journal of physiology 1992;448():539-50.
1992: Barbara Casadei; J Conway; Andrew J S Coats; R Bird
Antihypertensive effect of carvedilol: a preliminary dose-response study.
The Clinical investigator 1992;70 Suppl 1():S37-8.
1991: Barbara Casadei
Use of ambulatory blood pressure monitoring in pharmacological trials.
Journal of human hypertension 1991;5 Suppl 2():31-4.
1991: T E Meyer; Barbara Casadei; Andrew J S Coats; P P Davey; Stamatis Adamopoulos; Alberto Radaelli; J Conway
Angiotensin-converting enzyme inhibition and physical training in heart failure.
Journal of internal medicine 1991;230(5):407-13.
1989: Anna Grandi; achille venco; F Barzizza; Barbara Casadei; Eugenia Marchesi; Giorgio Finardi
Effect of enalapril on left ventricular mass and performance in essential hypertension.
The American journal of cardiology 1989;63(15):1093-7.
1989: Barbara Casadei; A Bertolini; F Sessa; achille venco
[Clinical assessment of syncopes].
Recenti progressi in medicina 1989;80(2):87-91.
1988: G Santoro; Barbara Casadei; achille venco
The transient global amnesia-migraine connection. Case report.
Functional neurology 1988;3(3):353-60.
1988: Anna Grandi; achille venco; F Barzizza; M Franchini; Barbara Casadei; Giorgio Finardi
Abnormal response to handgrip in hypertensive patients with increased left ventricular mass, assessed by echocardiography.
Acta cardiologica 1988;43(3):229-36.