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Paul S. Frenette

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Daigo Hashimoto; Marylene Leboeuf; Daniel Lucas-Alcaraz; Mary Beth Beasley; Christian D Becker; Scott W Boyer; Andrew Chow; E Camilla Forsberg; Paul S. Frenette; Adolfo García-Sastre; Ginhoux Florent; Melanie Greter; Arthur Mortha; Clara Noizat; Jeremy Price; Peter See; E Richard Stanley; Masato Tanaka; Pearline Teo; Nico van Rooijen; Miriam Merad
Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes.
Maher Hanoun; Paul S. Frenette
This niche is a maze; an amazing niche.
Andrew Chow; Jalal Ahmed; Aviv Bergman; Daigo Hashimoto; Matthew Huggins; Yuya Kunisaki; Marylene Leboeuf; Daniel Lucas; Miriam Merad; Clara Noizat; Sandra Pinho; Masato Tanaka; Nico van Rooijen; Zhizhuang Joe Zhao; Paul S. Frenette
CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress.

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All Publications

2013: Daigo Hashimoto; Marylene Leboeuf; Daniel Lucas-Alcaraz; Mary Beth Beasley; Christian D Becker; Scott W Boyer; Andrew Chow; E Camilla Forsberg; Paul S. Frenette; Adolfo García-Sastre; Ginhoux Florent; Melanie Greter; Arthur Mortha; Clara Noizat; Jeremy Price; Peter See; E Richard Stanley; Masato Tanaka; Pearline Teo; Nico van Rooijen; Miriam Merad
Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes.
Immunity 2013;38(4):792-804.
2013: Maher Hanoun; Paul S. Frenette
This niche is a maze; an amazing niche.
Cell stem cell 2013;12(4):391-2.
2013: Andrew Chow; Jalal Ahmed; Aviv Bergman; Daigo Hashimoto; Matthew Huggins; Yuya Kunisaki; Marylene Leboeuf; Daniel Lucas; Miriam Merad; Clara Noizat; Sandra Pinho; Masato Tanaka; Nico van Rooijen; Zhizhuang Joe Zhao; Paul S. Frenette
CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress.
Nature medicine 2013;19(4):429-36.
2013: Paul S. Frenette; Daniel Lucas-Alcaraz; Sandra Pinho; Christoph A. Scheiermann
Mesenchymal stem cell: keystone of the hematopoietic stem cell niche and a stepping-stone for regenerative medicine.
Annual review of immunology 2013;31():285-316.
2012: Camila Bononi Almeida; Nicola Conran; Fernando Ferreira Costa; Jung-Eun Jang; Colette Prophete; Christoph Scheiermann; Paul S. Frenette
Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice.
Blood 2012;120(14):2879-88.
2012: Jennifer C Miller; Gaurav Pandey; Jeremy Price; Gwendalyn J Randolph; Tal Shay; Shannon Turley; Angelique Bellemare-Pelletier; Milena Bogunovic; Brian D Brown; Andrew Chow; Ariella Cohain; Kutlu G Elpek; Paul S. Frenette; Emmanuel L Gautier; Melanie Greter; Daigo Hashimoto; Julie Helft; Vladimir Jojic; Marylene Leboeuf; Miriam Merad
Deciphering the transcriptional network of the dendritic cell lineage.
Nature immunology 2012;13(9):888-99.
2012: Christoph A. Scheiermann; Dachuan Zhang; Andrew Chow; Daigo Hashimoto; Jung-Eun Jang; Yuya Kunisaki; Daniel Lucas-Alcaraz; Miriam Merad; Paul S. Frenette
Adrenergic nerves govern circadian leukocyte recruitment to tissues.
Immunity 2012;37(2):290-301.
2012: Melanie Greter; Daigo Hashimoto; Julie Helft; Marylene Leboeuf; Geming Lu; Jennifer Miller; Arthur Mortha; Jeffrey W Pollard; Gwendalyn J Randolph; Huabao Xiong; Judith Agudo-Cantero; Costica Aloman; Milena Bogunovic; Brian D Brown; Jerry E Chipuk; Andrew Chow; Paul S. Frenette; Emmanuel L Gautier; Miriam Merad
GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells.
Immunity 2012;36(6):1031-46.
2012: Yuya Kunisaki; Paul S. Frenette
The secrets of the bone marrow niche: Enigmatic niche brings challenge for HSC expansion.
Nature medicine 2012;18(6):864-5.
2012: Daniel Lucas-Alcaraz; Claire Magnon; Simon Mendez-Ferrer; Michela Battista; Ingmar Bruns; Yuya Kunisaki; Paul S. Frenette
Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields.
Blood 2012;119(17):3962-5.
2012: Jung-Eun Jang; Andrés Hidalgo; Paul S. Frenette
Intravenous immunoglobulins modulate neutrophil activation and vascular injury through FcγRIII and SHP-1.
Circulation research 2012;110(8):1057-66.
2011: Francesca Ferraro; Paul S. Frenette; Gallia Graiani; Charles P Lin; Stefania Lymperi; Marcellina Mangoni; Elena Masselli; Simón Méndez-Ferrer; Lucia Prezioso; Federico Quaini; Elisa Lodi Rizzini; Vittorio Rizzoli; Borja Saez; Joel A Spencer; Stephen M Sykes; Beow Y Yeap; David T Scadden
Diabetes impairs hematopoietic stem cell mobilization by altering niche function.
Science translational medicine 2011;3(104):104ra101.
2011: Ayelet Dar; C E Dunbar; Paul S. Frenette; N Fujii; T Itkin; Alexander Kalinkovich; W-M Kao; Orit Kollet; Kfir Lapid; F Baleux; M Battista; H E Broxmeyer; E C Buss; N N Cohen; A Larochelle; A Ludin; R Margalit; S Oishi; A Schajnovitz; Melania Tesio; Tsvee Lapidot
Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells.
Leukemia 2011;25(8):1286-96.
2011: Daigo Hashimoto; Andrew Chow; Melanie Greter; Yvonne Saenger; Wing-Hong Kwan; Marylene Leboeuf; Ginhoux Florent; Jordi C Ochando; Yuya Kunisaki; Nico van Rooijen; Chen Liu; Takanori Teshima; Peter S Heeger; E Richard Stanley; Paul S. Frenette; Miriam Merad
Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation.
The Journal of experimental medicine 2011;208(5):1069-82.
2011: Maria Nácher; Ana Belén Blázquez; Bojing Shao; Adela Matesanz; Colette Prophete; M Cecilia Berin; Paul S. Frenette; Andrés Hidalgo
Physiological contribution of CD44 as a ligand for E-Selectin during inflammatory T-cell recruitment.
The American journal of pathology 2011;178(5):2437-46.
2011: Chao Shi; Ting Jia; Simon Mendez-Ferrer; Tobias M Hohl; Natalya V Serbina; Lauren Lipuma; Ingrid Leiner; Ming O Li; Paul S. Frenette; Eric G Pamer
Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands.
Immunity 2011;34(4):590-601.
2011: Jung-Eun Jang; Eldad A Hod; Steven L Spitalnik; Paul S. Frenette
CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.
The Journal of clinical investigation 2011;121(4):1397-401.
2011: Andrew Chow; Daniel Lucas-Alcaraz; Andrés Hidalgo; Simón Méndez-Ferrer; Daigo Hashimoto; Christoph A. Scheiermann; Michela Battista; Marylene Leboeuf; Colette Prophete; Nico van Rooijen; Masato Tanaka; Miriam Merad; Paul S. Frenette
Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.
The Journal of experimental medicine 2011;208(2):261-71.
2011: Claire Magnon; Daniel Lucas-Alcaraz; Paul S. Frenette
Trafficking of stem cells.
Methods in molecular biology (Clifton, N.J.) 2011;750():3-24.
2010: Jungshan Chang; John T Patton; Arun Sarkar; Beat Ernst; John L Magnani; Paul S. Frenette
GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice.
Blood 2010;116(10):1779-86.
2010: Simón Méndez-Ferrer; Tatyana V Michurina; Francesca Ferraro; Amin R Mazloom; Ben D MacArthur; Sergio A Lira; David T Scadden; Avi Ma'ayan; Grigori N Enikolopov; Paul S. Frenette
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche.
Nature 2010;466(7308):829-34.
2010: Paul S. Frenette; Narla Mohandas
Bad blood: a trigger for TRALI.
Nature medicine 2010;16(4):382-3.
2010: Simón Méndez-Ferrer; Michela Battista; Paul S. Frenette
Cooperation of beta(2)- and beta(3)-adrenergic receptors in hematopoietic progenitor cell mobilization.
Annals of the New York Academy of Sciences 2010;1192():139-44.
2010: Christoph A. Scheiermann; Yuya Kunisaki; Jung-Eun Jang; Paul S. Frenette
Neutrophil microdomains: linking heterocellular interactions with vascular injury.
Current opinion in hematology 2010;17(1):25-30.
2009: Simón Méndez-Ferrer; Andrew Chow; Miriam Merad; Paul S. Frenette
Circadian rhythms influence hematopoietic stem cells.
Current opinion in hematology 2009;16(4):235-42.
2009: Simón Méndez-Ferrer; Paul S. Frenette
Galpha(s) uncouples hematopoietic stem cell homing and mobilization.
Cell stem cell 2009;4(5):379-80.
2009: Andrés Hidalgo; Jungshan Chang; Jung-Eun Jang; Anna J Peired; Elaine Y Chiang; Paul S. Frenette
Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury.
Nature medicine 2009;15(4):384-91.
2009: Andrés Hidalgo; Paul S. Frenette
When integrins fail to integrate.
Nature medicine 2009;15(3):249-50.
2008: Daniel Lucas-Alcaraz; Michela Battista; Patricia A Shi; Luis Isola; Paul S. Frenette
Mobilized hematopoietic stem cell yield depends on species-specific circadian timing.
Cell stem cell 2008;3(4):364-6.
2008: Daniel Lucas-Alcaraz; Paul S. Frenette
Osteoblasts: yes, they can.
Blood 2008;112(3):455.
2008: Denisa D Wagner; Paul S. Frenette
The vessel wall and its interactions.
Blood 2008;111(11):5271-81.
2008: Simón Méndez-Ferrer; Daniel Lucas-Alcaraz; Michela Battista; Paul S. Frenette
Haematopoietic stem cell release is regulated by circadian oscillations.
Nature 2008;452(7186):442-7.
2008: Jungshan Chang; Patricia A Shi; Elaine Y Chiang; Paul S. Frenette
Intravenous immunoglobulins reverse acute vaso-occlusive crises in sickle cell mice through rapid inhibition of neutrophil adhesion.
Blood 2008;111(2):915-23.
2007: Simón Méndez-Ferrer; Paul S. Frenette
Hematopoietic stem cell trafficking: regulated adhesion and attraction to bone marrow microenvironment.
Annals of the New York Academy of Sciences 2007;1116():392-413.
2007: Andrés Hidalgo; Paul S. Frenette
Leukocyte podosomes sense their way through the endothelium.
Immunity 2007;26(6):753-5.
2007: Andrés Hidalgo; Anna J Peired; Martin K Wild; Dietmar Vestweber; Paul S. Frenette
Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44.
Immunity 2007;26(4):477-89.
2007: Paul S. Frenette; George F Atweh
Sickle cell disease: old discoveries, new concepts, and future promise.
The Journal of clinical investigation 2007;117(4):850-8.
2007: Elaine Y Chiang; Andrés Hidalgo; Jungshan Chang; Paul S. Frenette
Imaging receptor microdomains on leukocyte subsets in live mice.
Nature methods 2007;4(3):219-22.
2006: Milena Bogunovic; Ginhoux Florent; Amy J Wagers; Martine Loubeau; Luis Isola; Lauren Lubrano; Vesna Najfeld; Robert G Phelps; Celia Grosskreutz; Eileen Scigliano; Paul S. Frenette; Miriam Merad
Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men.
The Journal of experimental medicine 2006;203(12):2627-38.
2006: Véronique Angeli; Ginhoux Florent; Jaime Llodrà; Laurence Quemeneur; Paul S. Frenette; Mihaela Skobe; Rolf Jessberger; Miriam Merad; Gwendalyn J Randolph
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization.
Immunity 2006;24(2):203-15.
2006: Yoshio Katayama; Michela Battista; Wei-Ming Kao; Andrés Hidalgo; Anna J Peired; Steven A Thomas; Paul S. Frenette
Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow.
Cell 2006;124(2):407-21.
2005: Elaine Y Chiang; Paul S. Frenette
Sickle cell vaso-occlusion.
Hematology/oncology clinics of North America 2005;19(5):771-84, v.
2005: Yoshio Katayama; Andrés Hidalgo; Jungshan Chang; Anna J Peired; Paul S. Frenette
CD44 is a physiological E-selectin ligand on neutrophils.
The Journal of experimental medicine 2005;201(8):1183-9.
2005: Andrés Hidalgo; Paul S. Frenette
Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow.
Blood 2005;105(2):567-75.
2004: Andrea P Martin; Elizabeth C Coronel; Gen-ichiro Sano; Shu-Cheng Chen; Galya Vassileva; Claudia Canasto-Chibuque; Jonathon D Sedgwick; Paul S. Frenette; Martin Lipp; Glaucia C Furtado; sergio lira
A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):4791-8.
2004: Yoshio Katayama; Andrés Hidalgo; Anna J Peired; Paul S. Frenette
Integrin alpha4beta7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation.
Blood 2004;104(7):2020-6.
2004: Andrés Hidalgo; Anna J Peired; Linnea A Weiss; Yoshio Katayama; Paul S. Frenette
The integrin alphaMbeta2 anchors hematopoietic progenitors in the bone marrow during enforced mobilization.
Blood 2004;104(4):993-1001.
2004: Aslihan Turhan; Pegah Jenab; Pierre Bruhns; Jeffrey V Ravetch; Barry S Coller; Paul S. Frenette
Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes.
Blood 2004;103(6):2397-400.
2004: Paul S. Frenette
Sickle cell vasoocclusion: heterotypic, multicellular aggregations driven by leukocyte adhesion.
Microcirculation (New York, N.Y. : 1994) 2004;11(2):167-77.
2003: Jérôme Frenette; Nadia Chbinou; Charles Godbout; David Marsolais; Paul S. Frenette
Macrophages, not neutrophils, infiltrate skeletal muscle in mice deficient in P/E selectins after mechanical reloading.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;285(4):R727-32.
2003: Yoshio Katayama; Andrés Hidalgo; Barbara C Furie; Dietmar Vestweber; Bruce Furie; Paul S. Frenette
PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and alpha4 integrin.
Blood 2003;102(6):2060-7.
2003: Yoshio Katayama; Paul S. Frenette
Galactocerebrosides are required postnatally for stromal-dependent bone marrow lymphopoiesis.
Immunity 2003;18(6):789-800.
2003: Andrés Hidalgo; Songhui Ma; Anna J Peired; Linnea A Weiss; Charlotte Cunningham-Rundles; Paul S. Frenette
Insights into leukocyte adhesion deficiency type 2 from a novel mutation in the GDP-fucose transporter gene.
Blood 2003;101(5):1705-12.
2002: Andrés Hidalgo; Linnea A Weiss; Paul S. Frenette
Functional selectin ligands mediating human CD34(+) cell interactions with bone marrow endothelium are enhanced postnatally.
The Journal of clinical investigation 2002;110(4):559-69.
2002: Aslihan Turhan; Linnea A Weiss; Narla Mohandas; Barry S Coller; Paul S. Frenette
Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3047-51.
2002: Paul S. Frenette
Sickle cell vaso-occlusion: multistep and multicellular paradigm.
Current opinion in hematology 2002;9(2):101-6.
2001: Paul S. Frenette
Locking a leukocyte integrin with statins.
The New England journal of medicine 2001;345(19):1419-21.
2000: Paul S. Frenette; L Weiss
Sulfated glycans induce rapid hematopoietic progenitor cell mobilization: evidence for selectin-dependent and independent mechanisms.
Blood 2000;96(7):2460-8.
2000: Paul S. Frenette; Cécile V Denis; L Weiss; Kerstin Jurk; S Subbarao; Beate Kehrel; John H Hartwig; Dietmar Vestweber; Denisa D Wagner
P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo.
The Journal of experimental medicine 2000;191(8):1413-22.
1999: S D Robinson; Paul S. Frenette; Helen Rayburn; M Cummiskey; MH Ullman-Culleré; Denisa D Wagner; Richard O Hynes
Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11452-7.
1999: Keiichi Enjyoji; Jean Sévigny; Y Lin; Paul S. Frenette; PD Christie; J S Esch; M Imai; Jay M Edelberg; Helen Rayburn; Miroslaw Lech; David L Beeler; Eva Csizmadia; Denisa D Wagner; Simon C Robson; R D Rosenberg
Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation.
Nature medicine 1999;5(9):1010-7.
1999: Sulpicio G Soriano; Y F Wang; Denisa D Wagner; Paul S. Frenette
P- and E-selectin-deficient mice are susceptible to cerebral ischemia-reperfusion injury.
Brain research 1999;835(2):360-4.
1998: Paul S. Frenette; S Subbarao; Irina B Mazo; Ulrich H von Andrian; Denisa D Wagner
Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14423-8.
1998: DW Hartwell; Tanya N Mayadas; G Berger; Paul S. Frenette; Helen Rayburn; Richard O Hynes; Denisa D Wagner
Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses.
The Journal of cell biology 1998;143(4):1129-41.
1998: Jonathon W Homeister; M Zhang; Paul S. Frenette; R O Hynes; Denisa D Wagner; John B Lowe; Rory M Marks
Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation.
Blood 1998;92(7):2345-52.
1998: KP Seiler; Ying Ma; John H Weis; Paul S. Frenette; R O Hynes; D D Wagner; Janis J Weis
E and P selectins are not required for resistance to severe murine lyme arthritis.
Infection and immunity 1998;66(9):4557-9.
1998: C Denis; N Methia; Paul S. Frenette; Helen Rayburn; MH Ullman-Culleré; Richard O Hynes; Denisa D Wagner
A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9524-9.
1998: Irina B Mazo; JC Gutierrez-Ramos; Paul S. Frenette; Richard O Hynes; Denisa D Wagner; Ulrich H von Andrian
Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1.
The Journal of experimental medicine 1998;188(3):465-74.
1998: ZM Dong; SM Chapman; A A Brown; Paul S. Frenette; Richard O Hynes; Denisa D Wagner
The combined role of P- and E-selectins in atherosclerosis.
The Journal of clinical investigation 1998;102(1):145-52.
1998: F de Mora; C M Williams; Paul S. Frenette; D D Wagner; R O Hynes; Stephen J Galli
P- and E-selectins are required for the leukocyte recruitment, but not the tissue swelling, associated with IgE- and mast cell-dependent inflammation in mouse skin.
Laboratory investigation; a journal of technical methods and pathology 1998;78(4):497-505.
1998: Paul S. Frenette; C Moyna; DW Hartwell; J B Lowe; Richard O Hynes; Denisa D Wagner
Platelet-endothelial interactions in inflamed mesenteric venules.
Blood 1998;91(4):1318-24.
1998: DW Hartwell; Catherine E Butterfield; Paul S. Frenette; B M Kenyon; Richard O Hynes; Judah Folkman; Denisa D Wagner
Angiogenesis in P- and E-selectin-deficient mice.
Microcirculation (New York, N.Y. : 1994) 1998;5(2-3):173-8.
1997: Martin R Weiser; TT Pechet; JP Williams; Minghe Ma; Paul S. Frenette; Francis D Moore; Lester Kobzik; R O Hines; Denisa D Wagner; Michael C Carroll; Herbert B Hechtman
Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(4):1090-5.
1997: UM Walter; LM Ayer; A M Manning; Paul S. Frenette; D D Wagner; R O Hynes; B A Wolitzky; Andrew C Issekutz
Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin.
Hybridoma 1997;16(4):355-61.
1997: Paul S. Frenette; D D Wagner
Insights into selectin function from knockout mice.
Thrombosis and haemostasis 1997;78(1):60-4.
1997: M Subramaniam; Simin Saffaripour; Livingston Van De Water; Paul S. Frenette; Tanya N Mayadas; Richard O Hynes; Denisa D Wagner
Role of endothelial selectins in wound repair.
The American journal of pathology 1997;150(5):1701-9.
1996: Paul S. Frenette; Denisa D Wagner
Adhesion molecules--Part II: Blood vessels and blood cells.
The New England journal of medicine 1996;335(1):43-5.
1996: Paul S. Frenette; Denisa D Wagner
Adhesion molecules--Part 1.
The New England journal of medicine 1996;334(23):1526-9.
1996: T Tang; Paul S. Frenette; Richard O Hynes; Denisa D Wagner; Tanya N Mayadas
Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins.
The Journal of clinical investigation 1996;97(11):2485-90.
1996: Paul S. Frenette; Tanya N Mayadas; Helen Rayburn; Richard O Hynes; Denisa D Wagner
Double knockout highlights value of endothelial selectins.
Immunology today 1996;17(5):205.
1996: Paul S. Frenette; Tanya N Mayadas; Helen Rayburn; Richard O Hynes; Denisa D Wagner
Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins.
Cell 1996;84(4):563-74.
1996: M Subramaniam; Paul S. Frenette; S Saffaripour; R C Johnson; Richard O Hynes; Denisa D Wagner
Defects in hemostasis in P-selectin-deficient mice.
Blood 1996;87(4):1238-42.
1995: Paul S. Frenette; R C Johnson; Richard O Hynes; Denisa D Wagner
Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7450-4.
1995: R C Johnson; Tanya N Mayadas; Paul S. Frenette; R E Mebius; M Subramaniam; Ann S LaCasce; Richard O Hynes; Denisa D Wagner
Blood cell dynamics in P-selectin-deficient mice.
Blood 1995;86(3):1106-14.
1995: Paul S. Frenette; J F Desforges; David P Schenkein; A Rabson; C A Slapack; Kenneth B Miller
Granulocyte-macrophage colony stimulating factor (GM-CSF) priming in the treatment of elderly patients with acute myelogenous leukemia.
American journal of hematology 1995;49(1):48-55.
1994: Paul S. Frenette; M P Thirlwell; M Trudeau; D M Thomson; L Joseph; J S Shuster
The diagnostic value of CA 27-29, CA 15-3, mucin-like carcinoma antigen, carcinoembryonic antigen and CA 19-9 in breast and gastrointestinal malignancies.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1994;15(5):247-54.
1992: Paul S. Frenette; O B Paltiel; T Hudson; M Newkirk; A K Watters
Multiple myeloma presenting as migratory panniculitis.
International journal of dermatology 1992;31(6):424-5.