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Jindan YU

Research Profile

Disorders

Anatomy

Tumor Cell Line

Chemicals & Drugs

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Mouse

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Oligonucleotide Array Sequence Analysis

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Publications

TOP 3
Yeqing Angela Yang; Jindan YU
EZH2, an epigenetic driver of prostate cancer.
Jung Kim; Jindan YU
Interrogating genomic and epigenomic data to understand prostate cancer.
Jonathan C Zhao; Jianjun Yu; Ming Hu; Jun S Liu; Zhaohui S Qin; Christine Runkle; Qianben Wang; Dayong Wu; Longtao Wu; Jindan YU
Cooperation between Polycomb and androgen receptor during oncogenic transformation.

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All Publications

2013: Yeqing Angela Yang; Jindan YU
EZH2, an epigenetic driver of prostate cancer.
Protein & cell 2013;4(5):331-41.
2012: Jung Kim; Jindan YU
Interrogating genomic and epigenomic data to understand prostate cancer.
Biochimica et biophysica acta 2012;1825(2):186-96.
2012: Jonathan C Zhao; Jianjun Yu; Ming Hu; Jun S Liu; Zhaohui S Qin; Christine Runkle; Qianben Wang; Dayong Wu; Longtao Wu; Jindan YU
Cooperation between Polycomb and androgen receptor during oncogenic transformation.
Genome research 2012;22(2):322-31.
2011: Qi Cao; Xuhong Cao; Irfan A Asangani; Bushra Ateeq; J Chad Brenner; Arun Dahiya; Saravana M Dhanasekaran; Xiaojun Jing; Jung H Kim; Yong Li; Robert J Lonigro; Christopher A. Maher; Ram-Shankar Mani; Nallasivam Palanisamy; Mithil Pandhi; John R Prensner; Zhaohui Qin; Scott A Tomlins; Sooryanarayana Lnu; Lei Wang; Rui Wang; Yi-Mi Wu; Jindan YU; Arul M Chinnaiyan
Coordinated regulation of polycomb group complexes through microRNAs in cancer.
Cancer cell 2011;20(2):187-99.
2011: Jung H Kim; Hal D Kominsky; Christopher A. Maher; Rohit Mehra; Nallasivam Palanisamy; John R Prensner; Zhaohui S Qin; Daniel Robinson; Lee Sam; Sunita Shankar; Javed Siddiqui; Jindan YU; Saravana M Dhanasekaran; Catherine Grasso; Ming Hu; Christina Huang; Matthew Iyer; Xiaojun Jing; Shanker Kalyana-Sundaram; Xuhong Cao; Arul M Chinnaiyan
Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer.
Genome research 2011;21(7):1028-41.
2011: J Chad Brenner; Bushra Ateeq; Yong Li; Anastasia K Yocum; Qi Cao; Irfan A Asangani; Sonam Patel; Xiaoju Wang; Hallie Liang; Jindan YU; Nallasivam Palanisamy; Javed Siddiqui; Wei Yan; Xuhong Cao; Rohit Mehra; Aaron Sabolch; venkatesha basrur; Robert J Lonigro; Jun Yang; Scott A Tomlins; Christopher A. Maher; Kojo Seys John Elenitoba-Johnson; Maha Hussain; Nora M Navone; Kenneth Pienta; Sooryanarayana Lnu; Felix Y Feng; Arul M Chinnaiyan
Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.
Cancer cell 2011;19(5):664-78.
2010: Jindan YU; Qi Cao; J Yu; L Wu; A Dallol; J Li; Guoan Chen; C Grasso; Xuhong Cao; R J Lonigro; Sooryanarayana Lnu; Rohit Mehra; Nallasivam Palanisamy; J Y Wu; F Latif; Arul M Chinnaiyan
The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer.
Oncogene 2010;29(39):5370-80.
2010: Arun Sreekumar; Laila M Poisson; Thekkelnaycke Rajendiran; Amjad P Khan; Qi Cao; Jindan YU; Bharathi Laxman; Rohit Mehra; Robert J Lonigro; Yong Li; Mukesh K Nyati; Aarif Ahsan; Shanker Kalyana-Sundaram; Bo Han; Xuhong Cao; Jaeman Byun; Gilbert S Omenn; Debashis Ghoshd; Subramaniam Pennathur; Danny C Alexander; Alvin Berger; Jeffrey R Shuster; John T Wei; Sooryanarayana Lnu; Christopher W Beecher; Arul M Chinnaiyan
Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in urine after digital rectal examination fails as a marker in prostate cancer detection and identification of aggressive tumours. Eur Urol 2010;58:12-8.
European urology 2010;58(3):e29-30; author reply e31-2.
2010: Ian Lian; Joungmok Kim; Hideki Okazawa; Jiagang Zhao; Bin Zhao; Jindan YU; Arul M Chinnaiyan; Mason A Israel; Lawrence S B Goldstein; Ramzey Abujarour; Sheng Ding; Kun-Liang Guan
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation.
Genes & development 2010;24(11):1106-18.
2010: Jindan YU; Jianjun Yu; Ram-Shankar Mani; Qi Cao; Chad J Brenner; Xuhong Cao; Xiaoju Wang; Longtao Wu; James Li; Ming Hu; Yusong Gong; Hong Cheng; Bharathi Laxman; Adaikkalam Vellaichamy; Sunita Shankar; Yong Li; Saravana M Dhanasekaran; Roger Morey; Terrence barrette; Robert J Lonigro; Scott A Tomlins; Sooryanarayana Lnu; Zhaohui S Qin; Arul M Chinnaiyan
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression.
Cancer cell 2010;17(5):443-54.
2010: Ming Hu; Jindan YU; Jeremy Taylor; Arul M Chinnaiyan; Zhaohui S Qin
On the detection and refinement of transcription factor binding sites using ChIP-Seq data.
Nucleic acids research 2010;38(7):2154-67.
2010: Zhaohui S Qin; Jindan YU; Jincheng Shen; Christopher A. Maher; Ming Hu; Shanker Kalyana-Sundaram; Jianjun Yu; Arul M Chinnaiyan
HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data.
BMC bioinformatics 2010;11():369.
2009: Christopher A. Maher; Nallasivam Palanisamy; John C Brenner; Xuhong Cao; Shanker Kalyana-Sundaram; Shujun Luo; Irina Khrebtukova; Terrence barrette; Catherine Grasso; Jindan YU; Robert J Lonigro; Gary Schroth; Chandan Kumar; Arul M Chinnaiyan
Chimeric transcript discovery by paired-end transcriptome sequencing.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(30):12353-8.
2009: Qianben Wang; Wei Li; Yong Zhang; Xin Yuan; Kexin Xu; Jindan YU; Zhong Chen; Rameen Beroukhim; Hongyun Wang; Mathieu Lupien; Tao Wu; Meredith M Regan; Clifford A Meyer; Jason S Carroll; Arjun Kumar Manrai; Olli A Jänne; Steven P Balk; Rohit Mehra; Bo Han; Arul M Chinnaiyan; Mark A Rubin; Lawrence True; Michelangelo Fiorentino; Christopher Fiore; Massimo Loda; Philip W Kantoff; X Shirley Liu; Myles Brown
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer.
Cell 2009;138(2):245-56.
2009: Arun Sreekumar; Laila M Poisson; Thekkelnaycke Rajendiran; Amjad P Khan; Qi Cao; Jindan YU; Bharathi Laxman; Rohit Mehra; Robert J Lonigro; Yong Li; Mukesh K Nyati; Aarif Ahsan; Shanker Kalyana-Sundaram; Bo Han; Xuhong Cao; Jaeman Byun; Gilbert S Omenn; Debashis Ghosh; Subramaniam Pennathur; Danny C Alexander; Alvin Berger; Jeffrey R Shuster; John T Wei; Sooryanarayana Lnu; Christopher W Beecher; Arul M Chinnaiyan
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
Nature 2009;457(7231):910-4.
2009: Adaikkalam Vellaichamy; Arun Sreekumar; John R Strahler; Thekkelnaycke Rajendiran; Jindan YU; Sooryanarayana Lnu; Yong Li; Gilbert S Omenn; Arul M Chinnaiyan; Alexey I Nesvizhskii
Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases.
PloS one 2009;4(9):e7075.
2008: Sooryanarayana Lnu; Qi Cao; Ram-Shankar Mani; Sunita Shankar; Xiaosong Wang; Bushra Ateeq; Bharathi Laxman; Xuhong Cao; Xiaojun Jing; Kalpana Ramnarayanan; J Chad Brenner; Jindan YU; Jung H Kim; Bo Han; Patrick Tan; Chandan Kumar; Robert J Lonigro; Nallasivam Palanisamy; Christopher A. Maher; Arul M Chinnaiyan
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Science (New York, N.Y.) 2008;322(5908):1695-9.
2008: Q Cao; Jindan YU; Saravana M Dhanasekaran; J H Kim; R-S Mani; S A Tomlins; R Mehra; Bharathi Laxman; X Cao; J Yu; Celina G Kleer; Sooryanarayana Lnu; Arul M Chinnaiyan
Repression of E-cadherin by the polycomb group protein EZH2 in cancer.
Oncogene 2008;27(58):7274-84.
2008: Bo Han; Rohit Mehra; Saravana M Dhanasekaran; Jindan YU; Anjana Menon; Robert J Lonigro; Xiaosong Wang; Yusong Gong; Lei Wang; Sunita Shankar; Bharathi Laxman; Rajal B Shah; Sooryanarayana Lnu; Nallasivam Palanisamy; Scott A Tomlins; Chandan Kumar; Arul M Chinnaiyan
A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer.
Cancer research 2008;68(18):7629-37.
2008: Bin Zhao; Xin Ye; Jindan Yu; Li Li; Weiquan Li; Siming Li; Jindan YU; Jiandie Lin; Cun-Yu Wang; Arul M Chinnaiyan; Zhi-Chun Lai; Kun-Liang Guan
TEAD mediates YAP-dependent gene induction and growth control.
Genes & development 2008;22(14):1962-71.
2008: Scott A Tomlins; Bharathi Laxman; Sooryanarayana Lnu; Xuhong Cao; Jindan YU; Beth E Helgeson; Qi Cao; John R Prensner; Mark A Rubin; Rajal B Shah; Rohit Mehra; Arul M Chinnaiyan
Role of the TMPRSS2-ERG gene fusion in prostate cancer.
Neoplasia (New York, N.Y.) 2008;10(2):177-88.
2008: Jindan YU; Jindan Yu; Kevin E Cordero; Michael Johnson; Debashis Ghosh; James M Rae; Arul M Chinnaiyan; Marc Lippman
A transcriptional fingerprint of estrogen in human breast cancer predicts patient survival.
Neoplasia (New York, N.Y.) 2008;10(1):79-88.
2007: Jindan YU; Jianjun Yu; Daniel R Rhodes; Scott A Tomlins; Xuhong Cao; Guoan Chen; Rohit Mehra; Xiaoju Wang; Debashis Ghosh; Rajal B Shah; Sooryanarayana Lnu; Kenneth Pienta; Arul M Chinnaiyan
A polycomb repression signature in metastatic prostate cancer predicts cancer outcome.
Cancer research 2007;67(22):10657-63.
2007: Jindan YU; Qi Cao; Rohit Mehra; Bharathi Laxman; Jianjun Yu; Scott A Tomlins; Chad J Creighton; Saravana M Dhanasekaran; Ronglai Shen; Guoan Chen; David S Morris; Victor E Marquez; Rajal B Shah; Debashis Ghosh; Sooryanarayana Lnu; Arul M Chinnaiyan
Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer.
Cancer cell 2007;12(5):419-31.
2007: Bin Zhao; Xiaomu Wei; Weiquan Li; Ryan Udan; Qian Yang; Joungmok Kim; Joe Xie; Tsuneo Ikenoue; Jindan YU; Li Li; Pan Zheng; Keqiang Ye; Arul M Chinnaiyan; Georg Halder; Zhi-Chun Lai; Kun-Liang Guan
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.
Genes & development 2007;21(21):2747-61.
2007: Scott A Tomlins; Bharathi Laxman; Saravana M Dhanasekaran; Beth E Helgeson; Xuhong Cao; David S Morris; Anjana Menon; Xiaojun Jing; Qi Cao; Bo Han; Jindan YU; Lei Wang; James E Montie; Mark A Rubin; Kenneth Pienta; Diane Roulston; Rajal B Shah; Sooryanarayana Lnu; Rohit Mehra; Arul M Chinnaiyan
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer.
Nature 2007;448(7153):595-9.
2007: Jianjun Yu; Jindan YU; Arpit A Almal; Saravana M Dhanasekaran; Debashis Ghosh; William P Worzel; Arul M Chinnaiyan
Feature selection and molecular classification of cancer using genetic programming.
Neoplasia (New York, N.Y.) 2007;9(4):292-303.
2007: Guoan Chen; Xiaoju Wang; Jianjun Yu; Sooryanarayana Lnu; Jindan YU; Dafydd Thomas; Mu-Yen Lin; Prakash Vishnu; Zhuwen Wang; Rui Wang; Jeff Fielhauer; Debashis Ghosh; Thomas J Giordano; Donald Giacherio; Andrew C Chang; Mark B Orringer; Talal El-Hefnawy; William L Bigbee; David G Beer; Arul M Chinnaiyan
Autoantibody profiles reveal ubiquilin 1 as a humoral immune response target in lung adenocarcinoma.
Cancer research 2007;67(7):3461-7.
2004: Jindan YU; Shirley He; James S Friedman; Masayuki Akimoto; Debashis Ghosh; Alan J Mears; David Hicks; Anand Swaroop
Altered expression of genes of the Bmp/Smad and Wnt/calcium signaling pathways in the cone-only Nrl-/- mouse retina, revealed by gene profiling using custom cDNA microarrays.
The Journal of biological chemistry 2004;279(40):42211-20.
2004: Jindan YU; Alan J Mears; Shigeo Yoshida; Rafal Farjo; Todd A Carter; Debashis Ghosh; Alfred O Hero; Carrolee Barlow; Anand Swaroop
From disease genes to cellular pathways: a progress report.
Novartis Foundation symposium 2004;255():147-60; discussion 160-4, 177-8.
2003: Jindan YU; Rafal Farjo; Sean P MacNee; Wolfgang Baehr; Dwight E Stambolian; Anand Swaroop
Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.
Genome biology 2003;4(10):R65.
2002: Jindan YU; Mohammad I Othman; Rafal Farjo; Sepideh Zareparsi; Sean P MacNee; Shigeo Yoshida; Anand Swaroop
Evaluation and optimization of procedures for target labeling and hybridization of cDNA microarrays.
Molecular vision 2002;8():130-7.
2002: Rafal Farjo; Jindan YU; Mohammad I Othman; Shigeo Yoshida; Sujata Sheth; Thomas M Glaser; Wolfgang Baehr; Anand Swaroop
Mouse eye gene microarrays for investigating ocular development and disease.
Vision research 2002;42(4):463-70.