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Patrick Casara

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Sylvie Maubant; Dominique Saint-Dizier; Morgane Boutillon; Françoise Perron-Sierra; Patrick J Casara; John A Hickman; Gordon C Tucker; Ellen Van Obberghen-Schilling
Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.
Thierry Le Diguarher; Jean-Claude Ortuno; David Shanks; Nicolas Guilbaud; Alain Pierré; Eric Raimbaud; Jean-Luc Fauchère; John A Hickman; Gordon C Tucker; Patrick J Casara
Synthesis of N,N'-disubstituted 3-aminobenzo[c] and [d]azepin-2-ones as potent and specific farnesyl transferase inhibitors.
Thierry Le Diguarher; Anne-Marie Chollet; Marc Bertrand; Philippe Hennig; Eric Raimbaud; Massimo Sabatini; Nicolas Guilbaud; Alain Pierré; Gordon C Tucker; Patrick J Casara
Stereospecific synthesis of 5-substituted 2-bisarylthiocyclopentane carboxylic acids as specific matrix metalloproteinase inhibitors.

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All Publications

2006: Sylvie Maubant; Dominique Saint-Dizier; Morgane Boutillon; Françoise Perron-Sierra; Patrick J Casara; John A Hickman; Gordon C Tucker; Ellen Van Obberghen-Schilling
Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.
Blood 2006;108(9):3035-44.
2004: Thierry Le Diguarher; Jean-Claude Ortuno; David Shanks; Nicolas Guilbaud; Alain Pierré; Eric Raimbaud; Jean-Luc Fauchère; John A Hickman; Gordon C Tucker; Patrick J Casara
Synthesis of N,N'-disubstituted 3-aminobenzo[c] and [d]azepin-2-ones as potent and specific farnesyl transferase inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(3):767-71.
2003: Thierry Le Diguarher; Anne-Marie Chollet; Marc Bertrand; Philippe Hennig; Eric Raimbaud; Massimo Sabatini; Nicolas Guilbaud; Alain Pierré; Gordon C Tucker; Patrick J Casara
Stereospecific synthesis of 5-substituted 2-bisarylthiocyclopentane carboxylic acids as specific matrix metalloproteinase inhibitors.
Journal of medicinal chemistry 2003;46(18):3840-52.
2003: Thierry Le Diguarher; Jean-Claude Ortuno; Gilbert Dorey; David Shanks; Nicolas Guilbaud; Alain Pierré; Jean-Luc Fauchère; John A Hickman; Gordon C Tucker; Patrick J Casara
Parallel liquid synthesis of N,N'-Disubstituted 3-amino azepin-2-ones as potent and specific farnesyl transferase inhibitors.
Bioorganic & medicinal chemistry 2003;11(14):3193-204.
2003: Mike F Burbridge; Virginie Venot; Patrick J Casara; Françoise Perron-Sierra; John A Hickman; Gordon C Tucker
Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist.
Molecular pharmacology 2003;63(6):1281-8.
2002: Françoise Perron-Sierra; Dominique Saint Dizier; Marc Bertrand; Annie Genton; Gordon C Tucker; Patrick J Casara
Substituted benzocyloheptenes as potent and selective alpha(v) integrin antagonists.
Bioorganic & medicinal chemistry letters 2002;12(22):3291-6.
2002: Anne-Marie Chollet; Thierry Le Diguarher; Nathalie Kucharczyk; Armelle Loynel; Marc Bertrand; Gordon Tucker; Nicolas Guilbaud; Mike Burbridge; Philippe Pastoureau; Armel Fradin; Massimo Sabatini; Jean-Luc Fauchère; Patrick J Casara
Solid-phase synthesis of alpha-substituted 3-bisarylthio N-hydroxy propionamides as specific MMP inhibitors.
Bioorganic & medicinal chemistry 2002;10(3):531-44.
2001: Mark J Millan; Mauricette Brocco; Alain Gobert; G Dorey; Patrick J Casara; Anne Dekeyne
Anxiolytic properties of the selective, non-peptidergic CRF(1) antagonists, CP154,526 and DMP695: a comparison to other classes of anxiolytic agent.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(4):585-600.
2001: Brian Lockhart; N Bonhomme; Anita Roger; G Dorey; Patrick J Casara; Pierre Lestage
Protective effect of the antioxidant 6-ethoxy-2,2-pentamethylen-1,2-dihydroquinoline (S 33113) in models of cerebral neurodegeneration.
European journal of pharmacology 2001;416(1-2):59-68.
2001: Anne-Marie Chollet; Thierry Le Diguarher; L Murray; Marc Bertrand; Gordon C Tucker; Massimo Sabatini; Alain Pierré; Ghanem Atassi; J Bonnet; Patrick J Casara
General synthesis of alpha-substituted 3-bisaryloxy propionic acid derivatives as specific MMP inhibitors.
Bioorganic & medicinal chemistry letters 2001;11(3):295-9.
2000: Gerald M. Rosen; Pei Tsai; Eugene D Barth; G Dorey; Patrick J Casara; M Spedding; Howard J Halpern
A one-step synthesis of 2-(2-Pyridyl)-3H-indol-3-one N-oxide: is it an efficient spin trap for hydroxyl radical?
The Journal of organic chemistry 2000;65(14):4460-3.
2000: G Dorey; Brian Lockhart; Pierre Lestage; Patrick J Casara
New quinolinic derivatives as centrally active antioxidants.
Bioorganic & medicinal chemistry letters 2000;10(9):935-9.