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Douglas Burton

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John J Grzesiak; Robert M Hoffman; Sharmeela Kaushal; Cynthia S Snyder; Hop S Tran Cao; Fabian Vargas; Douglas Burton; Paul Clopton; Leonard J Deftos; Michael Bouvet
Knockdown of the β(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis.
Tracy M Downs; Douglas Burton; Flavio L Araiza; Randolph H Hastings; Leonard J Deftos
PTHrP stimulates prostate cancer cell growth and upregulates aldo-keto reductase 1C3.
Randolph H Hastings; Douglas Burton; Adel Nefzi; Philippe R Montgrain; Rick Quintana; Leonard J Deftos
Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression.

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2011: John J Grzesiak; Robert M Hoffman; Sharmeela Kaushal; Cynthia S Snyder; Hop S Tran Cao; Fabian Vargas; Douglas Burton; Paul Clopton; Leonard J Deftos; Michael Bouvet
Knockdown of the β(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis.
International journal of cancer. Journal international du cancer 2011;129(12):2905-15.
2011: Tracy M Downs; Douglas Burton; Flavio L Araiza; Randolph H Hastings; Leonard J Deftos
PTHrP stimulates prostate cancer cell growth and upregulates aldo-keto reductase 1C3.
Cancer letters 2011;306(1):52-9.
2010: Randolph H Hastings; Douglas Burton; Adel Nefzi; Philippe R Montgrain; Rick Quintana; Leonard J Deftos
Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression.
Cancer biology & therapy 2010;10(10):1067-75.
2007: Philippe R Montgrain; Rick Quintana; Yvette Rascon; Douglas Burton; Leonard J Deftos; Andrea Casillas; Randolph H Hastings
Parathyroid hormone-related protein varies with sex and androgen status in nonsmall cell lung cancer.
Cancer 2007;110(6):1313-20.
2007: John J Grzesiak; Kathy C Smith; Douglas Burton; Leonard J Deftos; Michael Bouvet
Integrin-mediated laminin-1 adhesion upregulates CXCR4 and IL-8 expression in pancreatic cancer cells.
Surgery 2007;141(6):804-14.
2007: Jessica L Brown; Douglas Burton; Leonard J Deftos; Amy A Smith; David W Pincus; Michael J Haller
Congenital craniopharyngioma and hypercalcemia induced by parathyroid hormone-related protein.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2007;13(1):67-71.
2006: John J Grzesiak; Douglas Burton; Leonard J Deftos; Michael Bouvet
Identification of DU 145 prostate cancer cell proteins that bind to the carboxy-terminal peptide of human PTHrP in vitro.
Peptides 2006;27(7):1898-901.
2006: Meng Yang; Douglas Burton; Jack Geller; Darren J Hillegonds; Randolph H Hastings; Leonard J Deftos; Robert M Hoffman
The bisphosphonate olpadronate inhibits skeletal prostate cancer progression in a green fluorescent protein nude mouse model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2602-6.
2006: Jared C Pache; Douglas Burton; Leonard J Deftos; Randolph H Hastings
A carboxyl leucine-rich region of parathyroid hormone-related protein is critical for nuclear export.
Endocrinology 2006;147(2):990-8.
2005: Robert L Fitzgerald; Darren J Hillegonds; Douglas Burton; Terrance L Griffin; Scott Mullaney; John S Vogel; Leonard J Deftos; David A Herold
41Ca and accelerator mass spectrometry to monitor calcium metabolism in end stage renal disease patients.
Clinical chemistry 2005;51(11):2095-102.
2005: John J Grzesiak; Kathy C Smith; Cheryl Chalberg; Caitlyn Truong; Douglas Burton; Leonard J Deftos; Michael Bouvet
Heat shock protein-70 expressed on the surface of cancer cells binds parathyroid hormone-related protein in vitro.
Endocrinology 2005;146(8):3567-76.
2005: Jose C Florez; Douglas Burton; Paula M Arnell; Leonard J Deftos; Anne Klibanski
Hypercalcemia and local production of parathyroid hormone-related protein by a perisellar rhabdomyosarcoma after remote pituitary irradiation.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2005;11(3):184-9.
2005: Douglas Burton; M Foster; K A Johnson; M Hiramoto; L J Deftos; R Terkeltaub
Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2005;13(5):395-404.
2005: John J Grzesiak; Kathy C Smith; Douglas Burton; Leonard J Deftos; Michael Bouvet
GSK3 and PKB/Akt are associated with integrin-mediated regulation of PTHrP, IL-6 and IL-8 expression in FG pancreatic cancer cells.
International journal of cancer. Journal international du cancer 2005;114(4):522-30.
2005: Douglas Burton; Jack Geller; Meng Yang; P Jiang; I Barken; Randolph H Hastings; Robert M Hoffman; Leonard J Deftos
Monitoring of skeletal progression of prostate cancer by GFP imaging, X-ray, and serum OPG and PTHrP.
The Prostate 2005;62(3):275-81.
2005: Leonard J Deftos; Israel Barken; Douglas Burton; Robert M Hoffman; Jack Geller
Direct evidence that PTHrP expression promotes prostate cancer progression in bone.
Biochemical and biophysical research communications 2005;327(2):468-72.
2005: John J Grzesiak; Kathy C Smith; Cheryl Chalberg; Douglas Burton; Leonard J Deftos; Michael Bouvet
Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells.
International journal of gastrointestinal cancer 2005;36(3):131-46.
2005: Igor Tsigelny; Douglas Burton; Yuriy Sharikov; Randolph H Hastings; L J Deftos
Coherent expression chromosome cluster analysis reveals differential regulatory functions of amino-terminal and distal parathyroid hormone-related protein domains in prostate carcinoma.
Journal of biomedicine & biotechnology 2005;2005(4):353-63.
2004: Francisco S Pardo; Winston W Lien; Howard S Fox; Jimmy T Efird; Joseph A Aguilera; Douglas Burton; Leonard J Deftos
Parathyroid hormone-related protein expression is correlated with clinical course in patients with glial tumors.
Cancer 2004;101(11):2622-8.
2004: Randolph H Hastings; Flavio Araiza; Douglas Burton; Maxwell Bedley; Leonard J Deftos
Parathyroid hormone-related protein regulates apoptosis in lung cancer cells through protein kinase A.
American journal of physiology. Cell physiology 2004;287(6):C1616-22.
2004: John J Grzesiak; Paul Clopton; Cheryl Chalberg; Kathy Smith; Douglas Burton; Steven A. Silletti; Abdool R Moossa; Leonard J Deftos; Michael Bouvet
The extracellular matrix differentially regulates the expression of PTHrP and the PTH/PTHrP receptor in FG pancreatic cancer cells.
Pancreas 2004;29(2):85-92.
2004: Randolph H Hastings; Flavio Araiza; Douglas Burton; Leonard J Deftos
Role of parathyroid hormone-related protein in lung cancer cell survival.
Chest 2004;125(5 Suppl):150S.
2003: Randolph H Hastings; Rick Quintana; Rebeca Sandoval; Douglas Burton; Leonard J Deftos
Amino-terminal and midmolecule parathyroid hormone-related protein, phosphatidylcholine, and type II cell proliferation in silica-injured lung.
American journal of physiology. Lung cellular and molecular physiology 2003;285(6):L1312-22.
2003: Randolph H Hastings; Flavio Araiza; Douglas Burton; Lu Zhang; Maxwell Bedley; Leonard J Deftos
Parathyroid hormone-related protein ameliorates death receptor-mediated apoptosis in lung cancer cells.
American journal of physiology. Cell physiology 2003;285(6):C1429-36.
2003: Randolph H Hastings; Rick Quintana; Rebeca Sandoval; Devin Duey; Yvette Rascon; Douglas Burton; Leonard J Deftos
Proapoptotic effects of parathyroid hormone-related protein in type II pneumocytes.
American journal of respiratory cell and molecular biology 2003;29(6):733-42.
2003: Matthew H Katz; Daniel Spivack; Shinako Takimoto; Bingliang Fang; Douglas Burton; Abdool R Moossa; Robert M Hoffman; Michael Bouvet
Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-related apoptosis-inducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter.
Annals of surgical oncology 2003;10(7):762-72.
2002: Manjiri M Bakre; Yuhong Zhu; Hong Yin; Douglas Burton; Robert Terkeltaub; Leonard J Deftos; Judith A Varner
Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor.
Nature medicine 2002;8(9):995-1003.
2002: Randolph H Hastings; Angela Asirvatham; Rick Quintana; Rebeca Sandoval; Ruchika Dutta; Douglas Burton; Leonard J Deftos
Parathyroid hormone-related protein-(38-64) regulates lung cell proliferation after silica injury.
American journal of physiology. Lung cellular and molecular physiology 2002;283(1):L12-21.
2002: Randolph H Hastings; Rita M Ryan; Carl T D'Angio; Bruce A Holm; Alka Patel; Rick Quintana; Elana Biederman; Douglas Burton; Leonard J Deftos
Parathyroid hormone-related protein response to hyperoxic lung injury.
American journal of physiology. Lung cellular and molecular physiology 2002;282(6):L1198-208.
2002: Michael Bouvet; Stephanie R Nardin; Douglas Burton; Natalie C Lee; Meng Yang; Xiaoen Wang; Eugene Baranov; cynthia behling; Abdool R Moossa; Robert M Hoffman; Leonard J Deftos
Parathyroid hormone-related protein as a novel tumor marker in pancreatic adenocarcinoma.
Pancreas 2002;24(3):284-90.
2001: Randolph H Hastings; Douglas Burton; Rick Quintana; Elana Biederman; A Gujral; Leonard J Deftos
Parathyroid hormone-related protein regulates the growth of orthotopic human lung tumors in athymic mice.
Cancer 2001;92(6):1402-10.
2001: A Gujral; Douglas Burton; R Terkeltaub; L J Deftos
Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanism not mediated by its classical nuclear localization sequence.
Cancer research 2001;61(5):2282-8.
2001: Michael Bouvet; Stephanie R Nardin; Douglas Burton; cynthia behling; John M Carethers; Abdool R Moossa; Leonard J Deftos
Human pancreatic adenocarcinomas express parathyroid hormone-related protein.
The Journal of clinical endocrinology and metabolism 2001;86(1):310-6.
2000: Randal Goomer; K A Johnson; Douglas Burton; David Amiel; Thira Maris; A Gurjal; L J Deftost; Robert Terkeltaub
The tetrabasic KKKK(147-150) motif determines intracrine regulatory effects of PthrP 1-173 on chondrocyte PPi metabolism and matrix synthesis.
Endocrinology 2000;141(12):4613-22.
2000: Randolph H Hastings; Douglas Burton; D Summers-Torres; Rick Quintana; Elana Biederman; Leonard J Deftos
Splenic, thymic, bony and lymph node metastases from orthotopic human lung carcinomas in immunocompromised mice.
Anticancer research 2000;20(5B):3625-9.
2000: Randolph H Hastings; J T Berg; D Summers-Torres; Douglas Burton; Leonard J Deftos
Parathyroid hormone-related protein reduces alveolar epithelial cell proliferation during lung injury in rats.
American journal of physiology. Lung cellular and molecular physiology 2000;279(1):L194-200.
1998: Elisabet Bucht; H Rong; Y Pernow; Ann-Christin Sandberg Nordqvist; E Eriksson; Wayne Rankin; E von Schoultz; W J Burtis; Barbro Granberg; U G Falkmer; Douglas Burton; L J Deftos
Parathyroid hormone-related protein in patients with primary breast cancer and eucalcemia.
Cancer research 1998;58(18):4113-6.
1998: S C Yeung; O Eton; Douglas Burton; L J Deftos; R Vassilopoulou-Sellin; R F Gagel
Hypercalcemia due to parathyroid hormone-related protein secretion by melanoma.
Hormone research 1998;49(6):288-91.
1997: Randolph H Hastings; D Summers-Torres; B Yaszay; J LeSueur; Douglas Burton; Leonard J Deftos
Parathyroid hormone-related protein, an autocrine growth inhibitor of alveolar type II cells.
The American journal of physiology 1997;272(3 Pt 1):L394-9.
1996: Leonard J Deftos; Douglas Burton; S M Baird; R A Terkeltaub
Hypercalcemia and systemic lupus erythematosus.
Arthritis and rheumatism 1996;39(12):2066-9.