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Kang-Yell Choi

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Eun Ji Ro; Pu-Hyeon Cha; Yong-Hee Cho; Joong-Soo Han; Hyun-Yi Kim; Jung-Won Park; Kang-Yell Choi
House dust mite allergen Der f 2 induces interleukin-13 expression by activating the PI3K/Akt pathway.
Doona Song; Misun Won; Jee Sun Yang; Kang-Yell Choi; Bo-Kyung Kim; Hwan Mook Kim; Seo Joong Kim; Kiho Lee; Kyeong Lee; Song-Kyu Park; Gyoonhee Han
Design, synthesis and biological evaluation of novel aliphatic amido/sulfonamido-quaternary ammonium salts as antitumor agents.
Mi-Yeon Kim; Byoung-San Moon; Kang-Yell Choi
Isolation and maintenance of cortical neural progenitor cells in vitro.

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2013: Eun Ji Ro; Pu-Hyeon Cha; Yong-Hee Cho; Joong-Soo Han; Hyun-Yi Kim; Jung-Won Park; Kang-Yell Choi
House dust mite allergen Der f 2 induces interleukin-13 expression by activating the PI3K/Akt pathway.
Immunologic research 2013;56(1):181-8.
2013: Doona Song; Misun Won; Jee Sun Yang; Kang-Yell Choi; Bo-Kyung Kim; Hwan Mook Kim; Seo Joong Kim; Kiho Lee; Kyeong Lee; Song-Kyu Park; Gyoonhee Han
Design, synthesis and biological evaluation of novel aliphatic amido/sulfonamido-quaternary ammonium salts as antitumor agents.
Bioorganic & medicinal chemistry 2013;21(3):788-94.
2013: Mi-Yeon Kim; Byoung-San Moon; Kang-Yell Choi
Isolation and maintenance of cortical neural progenitor cells in vitro.
Methods in molecular biology (Clifton, N.J.) 2013;1018():3-10.
2012: Phil-June Park; Won-Seok Park; Byoung-San Moon; Eun-Gyung Cho; Kang-Yell Choi; Ah-Reum Kim; Hyung-Jun Kim; Su-Na Kim; Soung-Hoon Lee; Tae Ryong Lee
Hair growth-promoting effect of Aconiti Ciliare Tuber extract mediated by the activation of Wnt/β-catenin signaling.
Life sciences 2012;91(19-20):935-43.
2012: Bora Kim; Hyuk Kim; Jin E Kim; Joo D Lee; Kang-Yell Choi; Seung H Lee
Co-treatment with retinyl retinoate and a PPARα agonist reduces retinoid dermatitis.
International journal of dermatology 2012;51(6):733-41.
2012: Woo-Jeong Jeong; Saluja Kaduwal; Hoguen Kim; Soung-Hoon Lee; Seung-Hoon Lee; Jong-Chan Park; Juyong Yoon; Jong-Bok Yoon; Kang-Yell Choi
Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis.
Science signaling 2012;5(219):ra30.
2012: Bu-Nam Jeon; Kyung-Sup Kim; Minjung Kim; Min-Kyeong Kim; Dong-In Koh; Kyung-Ryul Lee; Kenneth P Nephew; Juyong Yoon; Chae-Ok Yun; Kang-Yell Choi; Won-Il Choi; Sung-Yi Hong; Man-Wook Hur
KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A.
Cancer research 2012;72(5):1137-48.
2012: Soung-Hoon Lee; Do Sik Min; Muhammad Zahoor; Jae-Kwan Hwang; Kang-Yell Choi
Valproic acid induces cutaneous wound healing in vivo and enhances keratinocyte motility.
PloS one 2012;7(11):e48791.
2012: Soung-Hoon Lee; Do Sik Min; Phil June Park; Won-Seok Park; Seung Ho Shin; Juyong Yoon; Muhamad Zahoor; Hyoung Jun Kim; Hyun-Yi Kim; Kang-Yell Choi
Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells.
PloS one 2012;7(4):e34152.
2011: Bora Kim; Hyuk Kim; Jin Eun Kim; Myung Kyoo Kim; Joo Dong Lee; Jin Won Lee; Kye Jong Lee; Soung-Hoon Lee; Su Min Lee; Kang-Yell Choi
N-Nicotinoyl dopamine, a novel niacinamide derivative, retains high antioxidant activity and inhibits skin pigmentation.
Experimental dermatology 2011;20(11):950-2.
2011: Soung-Hoon Lee; Myoung Jin Oh; Juyong Yoon; Bora Kim; Hyun Yi Kim; Joo Dong Lee; Kye Jong Lee; Kang-Yell Choi
Persicaria hydropiper (L.) spach and its flavonoid components, isoquercitrin and isorhamnetin, activate the Wnt/β-catenin pathway and inhibit adipocyte differentiation of 3T3-L1 cells.
Phytotherapy research : PTR 2011;25(11):1629-35.
2011: Tsun-Wen Yao; Denise M T Yu; Kang-Yell Choi; Woo-Shin Kim; Geoffrey W McCaughan; George Sharbeen; Pu Xia; mark gorrell
A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling.
Molecular cancer research : MCR 2011;9(7):948-59.
2011: Min Kyoung Shin; Young Hoon Jang; Hyun Jung Yoo; Dong Woo Kang; Mi Hee Park; Mi Kyoung Kim; Ju Hyun Song; Sang Doo Kim; Gyesik Min; Hyung Keun You; Kang-Yell Choi; Yoe-Sik Bae; Do Sik Min
N-formyl-methionyl-leucyl-phenylalanine (fMLP) promotes osteoblast differentiation via the N-formyl peptide receptor 1-mediated signaling pathway in human mesenchymal stem cells from bone marrow.
The Journal of biological chemistry 2011;286(19):17133-43.
2011: Byoung-San Moon; Dong-Hwa Yang; Kyoung-Won Cho; Han-Sung Jung; Hyun-Yi Kim; Mi-Yeon Kim; Jong-Min Lee; Kang-Yell Choi
Sur8/Shoc2 involves both inhibition of differentiation and maintenance of self-renewal of neural progenitor cells via modulation of extracellular signal-regulated kinase signaling.
Stem cells (Dayton, Ohio) 2011;29(2):320-31.
2011: Dong Woo Kang; Kang-Yell Choi; Do Sik Min
Phospholipase D meets Wnt signaling: a new target for cancer therapy.
Cancer research 2011;71(2):293-7.
2011: Juyong Yoon; Kyoung-Hwa Koo; Kang-Yell Choi
MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy.
Cancer research 2011;71(2):445-53.
2010: M Y Kim; S Kaduwal; D H Yang; Kang-Yell Choi
Bone morphogenetic protein 4 stimulates attachment of neurospheres and astrogenesis of neural stem cells in neurospheres via phosphatidylinositol 3 kinase-mediated upregulation of N-cadherin.
Neuroscience 2010;170(1):8-15.
2010: Su-Hyung Park; Junsang Doh; S I Park; J Y Lim; S M Kim; J-I Youn; Hyun-Tak Jin; S-H Seo; M-Y Song; S Y Sung; M Kim; S J Hwang; J-M Choi; S-K Lee; H Y Lee; C L Lim; Y J Chung; D Yang; H-N Kim; Z H Lee; Kang-Yell Choi; S-S Jeun; Young Chul Sung
Branched oligomerization of cell-permeable peptides markedly enhances the transduction efficiency of adenovirus into mesenchymal stem cells.
Gene therapy 2010;17(8):1052-61.
2010: Dong Woo Kang; Soung-Hoon Lee; Jeong Whan Yoon; Won-Sang Park; Kang-Yell Choi; Do Sik Min
Phospholipase D1 drives a positive feedback loop to reinforce the Wnt/beta-catenin/TCF signaling axis.
Cancer research 2010;70(10):4233-42.
2010: Jin Eun Kim; Bora Kim; Hyuk Kim; Hyojung Kim; Joo Dong Lee; Hyun Jung Kim; Kang-Yell Choi; Seung Hun Lee
Retinyl retinoate induces hyaluronan production and less irritation than other retinoids.
The Journal of dermatology 2010;37(5):448-54.
2009: Kyoung-Won Cho; Jinglei Cai; Hyun-Yi Kim; Akihiro Hosoya; Hayato Ohshima; Kang-Yell Choi; Han-Sung Jung
ERK activation is involved in tooth development via FGF10 signaling.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2009;312(8):901-11.
2009: Chul-Yong Park; Soo-Ho Choi; Sang-Min Kang; Ju-Il Kang; Byung-Yoon Ahn; Hoguen Kim; Guhung Jung; Kang-Yell Choi; Soon B Hwang
Nonstructural 5A protein activates beta-catenin signaling cascades: implication of hepatitis C virus-induced liver pathogenesis.
Journal of hepatology 2009;51(5):853-64.
2009: Su-Min Kang; Seong-Jun Kim; Jung-Hee Kim; Wooseong Lee; Geon-Woo Kim; Kee-Ho Lee; Kang-Yell Choi; Jong-Won Oh
Interaction of hepatitis C virus core protein with Hsp60 triggers the production of reactive oxygen species and enhances TNF-alpha-mediated apoptosis.
Cancer letters 2009;279(2):230-7.
2009: Hae-Eun Kang; Y K Cho; Hwoon-Yong Jung; Kang-Yell Choi; S I Sohn; S R Baek; Myung Gull Lee
Pharmacokinetics and first-pass effects of liquiritigenin in rats: low bioavailability is primarily due to extensive gastrointestinal first-pass effect.
Xenobiotica; the fate of foreign compounds in biological systems 2009;39(6):465-75.
2009: Hee-Jung Lee; Jung-Min Koh; Joo-Yeon Hwang; Kang-Yell Choi; Seung Hun Lee; Eui Kyun Park; Tae-Ho Kim; Bok Ghee Han; Ghi Su Kim; Shin-Yoon Kim; Jong-Young Lee
Association of a RUNX2 promoter polymorphism with bone mineral density in postmenopausal Korean women.
Calcified tissue international 2009;84(6):439-45.
2009: Won-Il Choi; Bu-Nam Jeon; Chae-Ok Yun; Pyung-Hwan Kim; Sung-Eun Kim; Kang-Yell Choi; Se Hoon Kim; Man-Wook Hur
Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1.
The Journal of biological chemistry 2009;284(19):12633-44.
2009: Mi-Young Lee; Woo-Jeong Jeong; Jong-Won Oh; Kang-Yell Choi
NM23H2 inhibits EGF- and Ras-induced proliferation of NIH3T3 cells by blocking the ERK pathway.
Cancer letters 2009;275(2):221-6.
2009: Sung-Eun Kim; Ju-Yong Yoon; Woo-Jeong Jeong; Soung Hoo Jeon; Yoon Park; Jong-Bok Yoon; Y N Park; Hoguen Kim; Kang-Yell Choi
H-Ras is degraded by Wnt/beta-catenin signaling via beta-TrCP-mediated polyubiquitylation.
Journal of cell science 2009;122(Pt 6):842-8.
2009: Byoung-San Moon; Ju-Yong Yoon; Mi-Yeon Kim; Sang-Hun Lee; Thomas Choi; Kang-Yell Choi
Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway.
Experimental & molecular medicine 2009;41(2):116-25.
2009: Dong-Hwa Yang; Ju-Young Yoon; Soung-Hoon Lee; Vitezslav Bryja; Emma R Andersson; Ernest Arenas; Young-Guen Kwon; Kang-Yell Choi
Wnt5a is required for endothelial differentiation of embryonic stem cells and vascularization via pathways involving both Wnt/beta-catenin and protein kinase Calpha.
Circulation research 2009;104(3):372-9.
2008: Hyeong Ju Lee; Do Soo Jang; Hyung Joon Cha; Hye Seon Moon; Byung Hee Hong; Kang-Yell Choi; Hee Cheon Lee
NMR studies on the equilibrium unfolding of ketosteroid isomerase by urea.
Journal of biochemistry 2008;144(2):215-21.
2008: Hyeong Ju Lee; Ye Jeong Yoon; Do Soo Jang; Chul Kim; Hyung Joon Cha; Byung Hee Hong; Kang-Yell Choi; Hee Cheon Lee
15N NMR relaxation studies of Y14F mutant of ketosteroid isomerase: the influence of mutation on backbone mobility.
Journal of biochemistry 2008;144(2):159-66.
2008: Gyung-Ah Jung; Ju-Yong Yoon; Byoung-San Moon; Dong-Hwa Yang; Hyun-Yi Kim; Sang-Hun Lee; Vitezslav Bryja; Ernest Arenas; Kang-Yell Choi
Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway.
BMC cell biology 2008;9():66.
2008: Hyeong Ju Lee; Hye Seon Moon; Do Soo Jang; Hyung Jin Cha; Byung Hee Hong; Kang-Yell Choi; Hee Cheon Lee
Probing the equilibrium unfolding of ketosteroid isomerase through xenon-perturbed 1H-15N multidimensional NMR spectroscopy.
Journal of biomolecular NMR 2008;40(1):65-70.
2007: Soung Hoo Jeon; Woo-Jeong Jeong; Jae-Young Cho; Kee-Ho Lee; Kang-Yell Choi
Akt is involved in the inhibition of cell proliferation by EGF.
Experimental & molecular medicine 2007;39(4):491-8.
2007: Seong Kyu Song; Zina Moldoveanu; Huan Nguyen; Eui Ho Kim; Kang-Yell Choi; Jong Bae Kim; Jiri Mestecky
Intranasal immunization with influenza virus and Korean mistletoe lectin C (KML-C) induces heterosubtypic immunity in mice.
Vaccine 2007;25(34):6359-66.
2007: Sung-Eun Kim; Kang-Yell Choi
EGF receptor is involved in WNT3a-mediated proliferation and motility of NIH3T3 cells via ERK pathway activation.
Cellular signalling 2007;19(7):1554-64.
2007: Soung Hoo Jeon; Ju-Yong Yoon; Young Nyun Park; Woo-Jeong Jeong; Sewoon Kim; Eek-Hoon Jho; Young-Joon Surh; Kang-Yell Choi
Axin inhibits extracellular signal-regulated kinase pathway by Ras degradation via beta-catenin.
The Journal of biological chemistry 2007;282(19):14482-92.
2007: Sung-Eun Kim; Won-Jeong Lee; Kang-Yell Choi
The PI3 kinase-Akt pathway mediates Wnt3a-induced proliferation.
Cellular signalling 2007;19(3):511-8.
2007: Won-Jeong Lee; Dong-Uk Kim; Mi-Young Lee; Kang-Yell Choi
Identification of proteins interacting with the catalytic subunit of PP2A by proteomics.
Proteomics 2007;7(2):206-14.
2006: Young Sung Yun; Wook Lee; Sejeong Shin; Byung-Ha Oh; Kang-Yell Choi
Arg-158 is critical in both binding the substrate and stabilizing the transition-state oxyanion for the enzymatic reaction of malonamidase E2.
The Journal of biological chemistry 2006;281(52):40057-64.
2006: Joon-Hee Lee; Jung-Soo Lee; Sung-Eun Kim; Byoung-San Moon; Yong-Chul Kim; Sang-Kyou Lee; Sang-Kyou Lee; Kang-Yell Choi
Tautomycetin inhibits growth of colorectal cancer cells through p21cip/WAF1 induction via the extracellular signal-regulated kinase pathway.
Molecular cancer therapeutics 2006;5(12):3222-31.
2006: Yeun-Jin Ju; Jeong Eun Park; Kyoung Mi Juhn; Jaemin Jeong; Miyong Yun; Myung-Jin Park; Gil-Hong Park; Kang-Yell Choi; Myung-Haing Cho; Kwok-Kin Wong; Won-Bong Park; Kee-Ho Lee
Chromosomal end fusion resulting from telomere erosion increases susceptibility to radiation via multinucleation: effect of p53.
International journal of oncology 2006;29(4):753-63.
2006: Do Soo Jang; Hyeong Ju Lee; Byeongdu Lee; Byung Hee Hong; Hyung Jin Cha; Jinhwan Yoon; Kwanseop Lim; Ye Jeong Yoon; Jehan Kim; Moonhor Ree; Hee Cheon Lee; Kang-Yell Choi
Detection of an intermediate during the unfolding process of the dimeric ketosteroid isomerase.
FEBS letters 2006;580(17):4166-71.
2006: Ki-Sook Park; Soung Hoo Jeon; Sung-Eun Kim; Young Yil Bahk; Sheri L Holmen; Bart Williams; Kwang-Chul Chung; Young-Joon Surh; Kang-Yell Choi
APC inhibits ERK pathway activation and cellular proliferation induced by RAS.
Journal of cell science 2006;119(Pt 5):819-27.
2006: Soon Jin Oh; Bong Jin Hong; Kang-Yell Choi; Joon Won Park
Surface modification for DNA and protein microarrays.
Omics : a journal of integrative biology 2006;10(3):327-43.
2006: Jaemin Jeong; Su-Jin Hong; Yeun-Jin Ju; Bu-Yeo Kim; Myung-Jin Park; Tae-Hwan Kim; Chul-In Park; Kang-Yell Choi; Myung-Haing Cho; Sang-Hoon Kim; Hansoo Lee; Kee-Ho Lee
Temporal cDNA microarray analysis of gene expression in human hepatocellular carcinoma upon radiation exposure.
Oncology reports 2006;15(1):33-48.
2006: Joydip Kundu ; Kang-Yell Choi; Young-Joon Surh
beta-Catenin-mediated signaling: a novel molecular target for chemoprevention with anti-inflammatory substances.
Biochimica et biophysica acta 2006;1765(1):14-24.
2005: Jung-Ahn Lee; Dong-Chul Suh; Jae-Eun Kang; Myung-Hwa Kim; Hyejin Park; Min-Nyung Lee; Jung-Min Kim; Bu-Nam Jeon; Hee-Eun Roh; Mi-Young Yu; Kang-Yell Choi; Kyu Yeun Kim; Man-Wook Hur
Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK.
The Journal of biological chemistry 2005;280(30):28061-71.
2005: Young Sung Yun; Gyu Hyun Nam; Yeon-Gil Kim; Byung-Ha Oh; Kang-Yell Choi
Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B.
The FEBS journal 2005;272(8):1999-2011.
2005: Mi-Sun Yun; Sung-Eun Kim; Soung Hoo Jeon; Jung-Soo Lee; Kang-Yell Choi
Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation.
Journal of cell science 2005;118(Pt 2):313-22.
2005: Soon Jin Oh; Jimin Ju; Byung Chul Kim; Eunsil Ko; Bong Jin Hong; Jae-Gahb Park; Joon Won Park; Kang-Yell Choi
DNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 gene.
Nucleic acids research 2005;33(10):e90.
2004: Ki Sook Park; Soung Hoo Jeon; Jong-Won Oh; Kang-Yell Choi
p21Cip/WAF1 activation is an important factor for the ERK pathway dependent anti-proliferation of colorectal cancer cells.
Experimental & molecular medicine 2004;36(6):557-62.
2004: Bu-Yeo Kim; Je-Geun Lee; Sunhoo Park; Jae-Yeon Ahn; Yeun-Jin Ju; Jin-Haeng Chung; Chul Ju Han; Sook-Hyang Jeong; Young Il Yeom; Sangsoo Kim; Yong-Sung Lee; Chang-Min Kim; Eun-Mi Eom; Dong-Hee Lee; Kang-Yell Choi; Myung-Haing Cho; Kyung-Suk Suh; Dong-Wook Choi; Kee-Ho Lee
Feature genes of hepatitis B virus-positive hepatocellular carcinoma, established by its molecular discrimination approach using prediction analysis of microarray.
Biochimica et biophysica acta 2004;1739(1):50-61.
2004: Sung-Eun Kim; Jae-Young Cho; Kyung-Sup Kim; Su-Jun Lee; Ki-Hoo Lee; Kang-Yell Choi
Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells.
Cellular signalling 2004;16(11):1309-17.
2004: Daekyun Lee; Seung R Paik; Kang-Yell Choi
Beta-synuclein exhibits chaperone activity more efficiently than alpha-synuclein.
FEBS letters 2004;576(1-2):256-60.
2004: Do Soo Jang; Hyung Jin Cha; Sun-Shin Cha; Byung Hee Hong; Nam-Chul Ha; Ja Young Lee; Byung-Ha Oh; Heung-Soo Lee; Kang-Yell Choi
Structural double-mutant cycle analysis of a hydrogen bond network in ketosteroid isomerase from Pseudomonas putida biotype B.
The Biochemical journal 2004;382(Pt 3):967-73.
2004: Eun-Hee Yeon; Ju-Young Noh; Jong-Min Kim; Min-Young Lee; Sarah Yoon; Sang-Kyu Park; Kang-Yell Choi; Kyung-Sup Kim
Controlled transcriptional regulation in eukaryotes by a novel transcription factor derived from Escherichia coli purine repressor.
Biochemical and biophysical research communications 2004;319(2):334-41.
2004: Myungjin Kim; Guang-Ho Cha; Sunhong Kim; Jun Hee Lee; Jeehye Park; Hyongjong Koh; Kang-Yell Choi; Jongkyeong Chung
MKP-3 has essential roles as a negative regulator of the Ras/mitogen-activated protein kinase pathway during Drosophila development.
Molecular and cellular biology 2004;24(2):573-83.
2004: Kee-Ho Lee; Yu-Jin Jung; Chung-Il Hong; Myung-Haing Cho; Dong-Hoon Bai; Sang-Hoon Kim; Kang-Yell Choi; Ju-Hyun Yu; Chang-Min Kim
Activation of protein kinase C by 1-beta-D-arabinofuranosylcytosine conjugates of phospholipid.
International journal of oncology 2004;24(1):193-9.
2003: Sung-Eun Kim; Sun-Hong Kim; Kang-Yell Choi
Regulation of Drosophila MKP-3 by Drosophila ERK.
Annals of the New York Academy of Sciences 2003;1010():51-61.
2003: Ki-Sook Park; Nam-Gu Lee; Ki-Hoo Lee; Jeong Taeg Seo; Kang-Yell Choi
The ERK pathway involves positive and negative regulations of HT-29 colorectal cancer cell growth by extracellular zinc.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(6):G1181-8.
2003: Gyu Hyun Nam; Sun-Shin Cha; Young Sung Yun; Yun Hee Oh; Byung Hee Hong; Heung-Soo Lee; Kang-Yell Choi
The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.
The Biochemical journal 2003;375(Pt 2):297-305.
2003: Yong-Uk Kwon; Jungkyun Im; Gildon Choi; Young-Soo Kim; Kang-Yell Choi; Sung-Kee Chung
Synthesis of three enantiomeric pairs of scyllo-inositol phosphate and molecular interactions between all possible regioisomers of scyllo-inositol phosphate and inositol 1,4,5-trisphosphate 3-kinase.
Bioorganic & medicinal chemistry letters 2003;13(18):2981-4.
2003: Young Sung Yun; Tae-Hee Lee; Gyu Hyun Nam; Do Soo Jang; Sejeong Shin; Byung-Ha Oh; Kang-Yell Choi
Origin of the different pH activity profile in two homologous ketosteroid isomerases.
The Journal of biological chemistry 2003;278(30):28229-36.
2003: Sejeong Shin; Young Sung Yun; Hyun Min Koo; Yu Sam Kim; Kang-Yell Choi; Byung-Ha Oh
Characterization of a novel Ser-cisSer-Lys catalytic triad in comparison with the classical Ser-His-Asp triad.
The Journal of biological chemistry 2003;278(27):24937-43.
2003: Gyu Hyun Nam; Do-Hyung Kim; Nam-Chul Ha; Do Soo Jang; Young Sung Yun; Byung Hee Hong; Byung-Ha Oh; Kang-Yell Choi
Contribution of conserved amino acids at the dimeric interface to the conformational stability and the structural integrity of the active site in ketosteroid isomerase from Pseudomonas putida biotype B.
Journal of biochemistry 2003;134(1):101-10.
2002: Tae Il Kim; Soo Hyun Jin; Eun Hye Kang; Sug Kyun Shin; Kang-Yell Choi; Won Ho Kim
The role of mitogen-activated protein kinases and their relationship with NF-kappaB and PPARgamma in indomethacin-Induced apoptosis of colon cancer cells.
Annals of the New York Academy of Sciences 2002;973():241-5.
2002: Gyu Hyun Nam; Kang-Yell Choi
Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification.
European journal of biochemistry / FEBS 2002;269(21):5280-7.
2002: Ki-Sook Park; Yongho Ahn; Jin-Ah Kim; Mi-Sun Yun; Baik L Seong; Kang-Yell Choi
Extracellular zinc stimulates ERK-dependent activation of p21(Cip/WAF1) and inhibits proliferation of colorectal cancer cells.
British journal of pharmacology 2002;137(5):597-607.
2002: Young-Tae Chang; Gildon Choi; Yoe-Sik Bae; Matthew Burdett; Ho-Sang Moon; Jae Wook Lee; Nathanael S Gray; Peter G Schultz; Laurent Meijer; Sung-Kee Chung; Kang-Yell Choi; Pann-Ghill Suh; Sung Ho Ryu
Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase.
Chembiochem : a European journal of chemical biology 2002;3(9):897-901.
2002: Sunggoo Yun; Do Soo Jang; Gildon Choi; Kwang S Kim; Kang-Yell Choi; Hee Cheon Lee
Trifluoroethanol increases the stability of Delta(5)-3-ketosteroid isomerase. 15N NMR relaxation studies.
The Journal of biological chemistry 2002;277(26):23414-9.
2002: Byoung Heon Kang; Eunsil Ko; Oh-Keun Kwon; Kang-Yell Choi
The structure of procaspase 6 is similar to that of active mature caspase 6.
The Biochemical journal 2002;364(Pt 3):629-34.
2002: Jin-Ah Kim; Ki-Sook Park; Ha-Il Kim; So-Young Oh; Yongho Ahn; Jong-Won Oh; Kang-Yell Choi
Troglitazone activates p21Cip/WAF1 through the ERK pathway in HCT15 human colorectal cancer cells.
Cancer letters 2002;179(2):185-95.
2002: Hyung-Bae Kwon; Sun-Hong Kim; Sung-Eun Kim; In-Hwan Jang; Yongho Ahn; Won-Jae Lee; Kang-Yell Choi
Drosophila extracellular signal-regulated kinase involves the insulin-mediated proliferation of Schneider cells.
The Journal of biological chemistry 2002;277(17):14853-8.
2002: Sang-Jun Ha; Jun Chang; Man K Song; You-Suk Suh; Hyun-Tak Jin; Chu H Lee; Gyu Hyun Nam; Gildon Choi; Kang-Yell Choi; Sung H Lee; Won Bae Kim; Young Chul Sung
Engineering N-glycosylation mutations in IL-12 enhances sustained cytotoxic T lymphocyte responses for DNA immunization.
Nature biotechnology 2002;20(4):381-6.
2002: So-Young Oh; Ki-Sook Park; Jin-Ah Kim; Kang-Yell Choi
Differential modulation of zinc-stimulated p21(Cip/WAF1) and cyclin D1 induction by inhibition of PI3 kinase in HT-29 colorectal cancer cells.
Experimental & molecular medicine 2002;34(1):27-31.
2002: Ha-Il Kim; Ji-Young Cha; So-Youn Kim; Jae-woo Kim; Kyung Jin Roh; Je Kyung Seong; Nam Taek Lee; Kang-Yell Choi; Kyung-Sup Kim; Yong-Ho Ahn
Peroxisomal proliferator-activated receptor-gamma upregulates glucokinase gene expression in beta-cells.
Diabetes 2002;51(3):676-85.
2002: Sun-Hong Kim; Hyung-Bae Kwon; YONG-SIK KIM; Ji-Hwan Ryu; Kyung-Sub Kim; Yongho Ahn; Won-Jae Lee; Kang-Yell Choi
Isolation and characterization of a Drosophila homologue of mitogen-activated protein kinase phosphatase-3 which has a high substrate specificity towards extracellular-signal-regulated kinase.
The Biochemical journal 2002;361(Pt 1):143-51.
2001: Nam-Chul Ha; Gildon Choi; Kang-Yell Choi; Byung-Ha Oh
Structure and enzymology of Delta5-3-ketosteroid isomerase.
Current opinion in structural biology 2001;11(6):674-8.
2001: Gyu Hyun Nam; Do Soo Jang; Sun-Shin Cha; Tae-Hee Lee; Dong H Kim; Byung Hee Hong; Young Sung Yun; Byung-Ha Oh; Kang-Yell Choi
Maintenance of alpha-helical structures by phenyl rings in the active-site tyrosine triad contributes to catalysis and stability of ketosteroid isomerase from Pseudomonas putida biotype B.
Biochemistry 2001;40(45):13529-37.
2001: Jae Hyun Cho; D H Kim; Kong-Joo Lee; Dong H Kim; Kang-Yell Choi
The role of Tyr248 probed by mutant bovine carboxypeptidase A: insight into the catalytic mechanism of carboxypeptidase A.
Biochemistry 2001;40(34):10197-203.
2001: Gildon Choi; Nam-Chul Ha; Mi-Sung Kim; Byung Hee Hong; Byung-Ha Oh; Kang-Yell Choi
Pseudoreversion of the catalytic activity of Y14F by the additional substitution(s) of tyrosine with phenylalanine in the hydrogen bond network of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Biochemistry 2001;40(23):6828-35.
2001: T I Kim; S H Jin; Won Ho Kim; E H Kang; Kang-Yell Choi; H J Kim; Sug Kyun Shin; J K Kang
Prolonged activation of mitogen-activated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells.
International journal of colorectal disease 2001;16(3):167-73.
2001: Dong H Kim; Do Soo Jang; Gyu Hyun Nam; Kang-Yell Choi
Folding mechanism of ketosteroid isomerase from Comamonas testosteroni.
Biochemistry 2001;40(16):5011-7.
2001: Dong H Kim; Gyu Hyun Nam; Do Soo Jang; Sunggoo Yun; Gildon Choi; Hee Cheon Lee; Kang-Yell Choi
Roles of dimerization in folding and stability of ketosteroid isomerase from Pseudomonas putida biotype B.
Protein science : a publication of the Protein Society 2001;10(4):741-52.
2000: Nam-Chul Ha; Mi-Sung Kim; Weontae Lee; Kang-Yell Choi; Byung-Ha Oh
Detection of large pKa perturbations of an inhibitor and a catalytic group at an enzyme active site, a mechanistic basis for catalytic power of many enzymes.
The Journal of biological chemistry 2000;275(52):41100-6.
2000: Kyung Seok Oh; Sun-Shin Cha; Dong H Kim; Hyun-Soo Cho; Nam-Chul Ha; Gildon Choi; Jin Yong Lee; P Tarakeshwar; Hyeon S Son; Kang-Yell Choi; Byung-Ha Oh; K S Kim
Role of catalytic residues in enzymatic mechanisms of homologous ketosteroid isomerases.
Biochemistry 2000;39(45):13891-6.
2000: DC Hwang; Dae Heon Kim; J S Lee; BH Kang; J Han; W Kim; BD Song; Kang-Yell Choi
Characterization of active-site residues of the NIa protease from tobacco vein mottling virus.
Molecules and cells 2000;10(5):505-11.
2000: Dong H Kim; Do Soo Jang; Gyu Hyun Nam; Sunggoo Yun; Jae Hyun Cho; Gildon Choi; Hee Cheon Lee; Kang-Yell Choi
Equilibrium and kinetic analysis of folding of ketosteroid isomerase from Comamonas testosteroni.
Biochemistry 2000;39(42):13084-92.
2000: W J Lee; Sun-Hong Kim; YONG-SIK KIM; S J Han; K S Park; J H Ryu; Man-Wook Hur; Kang-Yell Choi
Inhibition of mitogen-activated protein kinase by a Drosophila dual-specific phosphatase.
The Biochemical journal 2000;349 Pt 3():821-8.
2000: D Kim; BH Kang; J S Han; Kang-Yell Choi
Temperature and salt effects on proteolytic function of turnip mosaic potyvirus nuclear inclusion protein a exhibiting a low-temperature optimum activity.
Biochimica et biophysica acta 2000;1480(1-2):29-40.
2000: Byung-Chang Suh; Myung-Jun Kim; G Choi; Kang-Yell Choi; J K Han; Sung-Kee Chung; Kyong-Tai Kim
Differential stereoselectivity of D- and L-myo-inositol 1,2,4, 5-tetrakisphosphate binding to the inositol 1,4,5-trisphosphate receptor and 3-kinase.
Neurochemistry international 2000;37(1):47-52.
2000: Y J Choi; S K Kim; Sun-Hong Kim; K S Lee; Kang-Yell Choi
Saccharomyces cerevisiae Ste5 is important for induction and substrate specificity of Fus3 MAP kinase in the pheromone signaling pathway.
Molecules and cells 2000;10(3):301-8.
2000: H Y Yoon; DC Hwang; Kang-Yell Choi; BD Song
Proteolytic processing of oligopeptides containing the target sequences by the recombinant tobacco vein mottling virus NIa proteinase.
Molecules and cells 2000;10(2):213-9.
2000: DC Hwang; Dae Heon Kim; BH Kang; BD Song; Kang-Yell Choi
Molecular cloning, expression, and purification of nuclear inclusion A protease from tobacco vein mottling virus.
Molecules and cells 2000;10(2):148-55.
2000: Dong H Kim; Do Soo Jang; Gyu Hyun Nam; Gildon Choi; JS Kim; Nam-Chul Ha; Mi-Sung Kim; Byung-Ha Oh; Kang-Yell Choi
Contribution of the hydrogen-bond network involving a tyrosine triad in the active site to the structure and function of a highly proficient ketosteroid isomerase from Pseudomonas putida biotype B.
Biochemistry 2000;39(16):4581-9.
2000: Gildon Choi; Nam-Chul Ha; SW Kim; Dong H Kim; S Park; Byung-Ha Oh; Kang-Yell Choi
Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Biochemistry 2000;39(5):903-9.
2000: H Y Yoon; Kang-Yell Choi; BD Song
Fluorometric assay of turnip mosaic virus NIa protease.
Analytical biochemistry 2000;277(2):228-31.
1999: K S Park; Nam-Gyun Kim; J J Kim; JungJin Kim; Yong-Ho Ahn; Kang-Yell Choi
Differential regulation of MAP kinase cascade in human colorectal tumorigenesis.
British journal of cancer 1999;81(7):1116-21.
1999: Hyun-Soo Cho; Nam-Chul Ha; Gildon Choi; Hyun-Ju Kim; D Lee; Kyung Seok Oh; K S Kim; Weontae Lee; Kang-Yell Choi; Byung-Ha Oh
Crystal structure of delta(5)-3-ketosteroid isomerase from Pseudomonas testosteroni in complex with equilenin settles the correct hydrogen bonding scheme for transition state stabilization.
The Journal of biological chemistry 1999;274(46):32863-8.
1999: Dong H Kim; Gyu Hyun Nam; Do Soo Jang; Gildon Choi; S Joo; JS Kim; Byung-Ha Oh; Kang-Yell Choi
Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.
Biochemistry 1999;38(42):13810-9.
1999: Jong-So Kim; Sun-Shin Cha; Hyun-Ju Kim; Tae-Jip Kim; Nam-Chul Ha; S T Oh; Hyun-Soo Cho; M J Cho; Min-Jung Kim; Heung-Soo Lee; J W Kim; Kang-Yell Choi; Kwan-Hwa Park; Byung-Ha Oh
Crystal structure of a maltogenic amylase provides insights into a catalytic versatility.
The Journal of biological chemistry 1999;274(37):26279-86.
1999: Sun-Shin Cha; H C Shin; Kang-Yell Choi; Byung-Ha Oh
Expression, purification and crystallization of recombinant human TRAIL.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 5):1101-4.
1999: Y J Choi; Sun-Hong Kim; K S Park; Kang-Yell Choi
Differential transmission of G1 cell cycle arrest and mating signals by Saccharomyces cerevisiae Ste5 mutants in the pheromone pathway.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1999;77(5):459-68.
1998: Kisun Jun; G Choi; S G Yang; Kang-Yell Choi; H Kim; G C Chan; D R Storm; C Albert; G W Mayr; C J Lee; Hee-Sup Shin
Enhanced hippocampal CA1 LTP but normal spatial learning in inositol 1,4,5-trisphosphate 3-kinase(A)-deficient mice.
Learning & memory (Cold Spring Harbor, N.Y.) 1998;5(4-5):317-30.
1998: Hyun-Soo Cho; Gildon Choi; Kang-Yell Choi; Byung-Ha Oh
Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.
Biochemistry 1998;37(23):8325-30.
1998: Sun-Hong Kim; Sang-Kyou Lee; Kang-Yell Choi
Saccharomyces cerevisiae STE11 may contribute to the stabilities of a scaffold protein, STE5, in the pheromone signaling pathway.
Molecules and cells 1998;8(2):130-7.
1998: Dae Heon Kim; J S Han; J Lew; S S Kim; BH Kang; DC Hwang; D S Jang; W Kim; BD Song; Kang-Yell Choi
Effects of mutations in the C-terminal region of NIa protease on cis-cleavage between NIa and NIb.
Virology 1998;241(1):94-100.
1998: Zhe Piao; Chanil Park; J S Lee; C H Yang; Kang-Yell Choi; Hoguen Kim
Homozygous deletions of the CDKN2 gene and loss of heterozygosity of 9p in primary hepatocellular carcinoma.
Cancer letters 1998;122(1-2):201-7.
1998: SJ Han; Kang-Yell Choi; Paul T Brey; W J Lee
Molecular cloning and characterization of a Drosophila p38 mitogen-activated protein kinase.
The Journal of biological chemistry 1998;273(1):369-74.
1997: SW Kim; S Joo; Gildon Choi; Hyun-Soo Cho; Byung-Ha Oh; Kang-Yell Choi
Mutational analysis of the three cysteines and active-site aspartic acid 103 of ketosteroid isomerase from Pseudomonas putida biotype B.
Journal of bacteriology 1997;179(24):7742-7.
1997: SW Kim; Sun-Shin Cha; Hyun-Soo Cho; JS Kim; Nam-Chul Ha; M J Cho; S Joo; K K Kim; Kang-Yell Choi; Byung-Ha Oh
High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue.
Biochemistry 1997;36(46):14030-6.
1996: D H Kim; D C Hwang; B H Kang; J Lew; J Han; B D Song; Kang-Yell Choi
Effects of internal cleavages and mutations in the C-terminal region of NIa protease of turnip mosaic potyvirus on the catalytic activity.
Virology 1996;226(2):183-90.
1996: D H Kim; D C Hwang; B H Kang; J Lew; Kang-Yell Choi
Characterization of Nla protease from turnip mosaic potyvirus exhibiting a low-temperature optimum catalytic activity.
Virology 1996;221(1):245-9.
1996: Byung-Ha Oh; S W Kim; S E Ryu; S S Kim; M K Yoon; Kang-Yell Choi
Crystallization and preliminary x-ray crystallographic studies of ketosteroid isomerase from Pseudomonas putida biotype B.
Proteins 1996;24(4):514-5.
1995: J H Goo; K H Kim; Kang-Yell Choi
Cloning, sequencing and expression of the gene encoding a major allotypic preprocarboxypeptidase A from bovine pancreas.
Gene 1995;165(2):333-4.
1995: D H Kim; Y S Park; S S Kim; J Lew; H G Nam; Kang-Yell Choi
Expression, purification, and identification of a novel self-cleavage site of the Nla C-terminal 27-kDa protease of turnip mosaic potyvirus C5.
Virology 1995;213(2):517-25.
1995: J Chang; D H Kim; S W Lee; Kang-Yell Choi; Young Chul Sung
Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein.
The Journal of biological chemistry 1995;270(42):25014-9.
1995: Maria A Schumacher; Kang-Yell Choi; F Lu; H Zalkin; Richard G Brennan
Mechanism of corepressor-mediated specific DNA binding by the purine repressor.
Cell 1995;83(1):147-55.
1995: S W Kim; Kang-Yell Choi
Identification of active site residues by site-directed mutagenesis of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Journal of bacteriology 1995;177(9):2602-5.
1994: Maria A Schumacher; Kang-Yell Choi; H Zalkin; Richard G Brennan
Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.
Science (New York, N.Y.) 1994;266(5186):763-70.
1994: S W Kim; C Y Kim; W F Benisek; Kang-Yell Choi
Cloning, nucleotide sequence, and overexpression of the gene coding for delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Journal of bacteriology 1994;176(21):6672-6.
1994: Maria A Schumacher; Kang-Yell Choi; H Zalkin; Richard G Brennan
Crystallization and preliminary X-ray analysis of an Escherichia coli purine repressor-hypoxanthine-DNA complex.
Journal of molecular biology 1994;242(3):302-5.
1993: Bernadette C Taylor; Kang-Yell Choi; R J Scibienski; Peter F Moore; Jeffrey L Stott
Differential expression of bovine MHC class II antigens identified by monoclonal antibodies.
Journal of leukocyte biology 1993;53(5):479-89.
1992: Maria A Schumacher; Kang-Yell Choi; H Zalkin; Richard G Brennan
Crystallization and preliminary X-ray studies on the co-repressor binding domain of the Escherichia coli purine repressor.
Journal of molecular biology 1992;225(4):1131-3.
1988: Kang-Yell Choi; W F Benisek
Nucleotide sequence of the gene for the delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni.
Gene 1988;69(1):121-9.
1987: Kang-Yell Choi; W F Benisek
Cloning of the gene for delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.
Gene 1987;58(2-3):257-64.