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Ingolf Cascorbi

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Ingolf Cascorbi; Oliver Bruhn; Anneke N Werk
Challenges in pharmacogenetics.
Ingolf Cascorbi; Frank Faltraco; Charlotte Flüh; Maria Grumbt; Sierk Haenisch; Michele Peters; Cornelia Remmler; Dietmar Rudolf Thal; Anja Brenn; Rolf Wolfgang Warzok; Silke Vogelgesang
Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease.
Ingolf Cascorbi
Correspondence (reply): In Reply.

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All Publications

2013: Ingolf Cascorbi; Oliver Bruhn; Anneke N Werk
Challenges in pharmacogenetics.
European journal of clinical pharmacology 2013;69 Suppl 1():17-23.
2013: Ingolf Cascorbi; Frank Faltraco; Charlotte Flüh; Maria Grumbt; Sierk Haenisch; Michele Peters; Cornelia Remmler; Dietmar Rudolf Thal; Anja Brenn; Rolf Wolfgang Warzok; Silke Vogelgesang
Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease.
Pharmacogenomics 2013;14(5):485-94.
2013: Ingolf Cascorbi
Correspondence (reply): In Reply.
Deutsches Ärzteblatt international 2013;110(8):133.
2012: Denisa May; Maria Raphaela Nientit; Michael Schünke; Jonas Baastrup; Ralf Baron; Andreas Binder; Ingolf Cascorbi
Differential expression and functionality of TRPA1 protein genetic variants in conditions of thermal stimulation.
The Journal of biological chemistry 2012;287(32):27087-94.
2012: Ingolf Cascorbi
Drug interactions--principles, examples and clinical consequences.
Deutsches Ärzteblatt international 2012;109(33-34):546-55; quiz 556.
2012: Sierk Haenisch; Ingolf Cascorbi
miRNAs as mediators of drug resistance.
Epigenomics 2012;4(4):369-81.
2012: Anneke Nina Werk; Ingolf Cascorbi
Conference Scene: Pharmacogenomic highlights of the DGPT Annual Congress.
Pharmacogenomics 2012;13(9):997-9.
2012: Jayne Catherine Fox; Hans Linden; Ana Alfirevic; Ingolf Cascorbi; Ann Daly; Anke Hilse Maitland-van der Zee
5th Anniversary meeting of the European Research Network Pharmacogenetics/Pharmacogenomics. 8-9 December 2011, Utrecht, The Netherlands.
Pharmacogenomics 2012;13(7):747-9.
2012: Jonathan Krell; Ingolf Cascorbi; Adam E Frampton; Anneke Werk; Justin Stebbing
Highlights from the latest articles in breast cancer pharmacogenomics.
Pharmacogenomics 2012;13(6):645-9.
2012: Nasir Ali Afsar; Hakimuddin Razi Ahmad; Khwaja Zafar Ahmed; Sierk Haenisch; Ahmed Mateen; Cornelia Remmler; Mike Ufer; Ahmed Usman; Ingolf Cascorbi
Relationship of drug metabolizing enzyme genotype to plasma levels as well as myelotoxicity of cyclophosphamide in breast cancer patients.
European journal of clinical pharmacology 2012;68(4):389-95.
2012: Eleonora Turrini; Oliver Bruhn; Tobias Diewock; Sierk Haenisch; Sandra Laechelt; Ingolf Cascorbi
MicroRNA profiling in K-562 cells under imatinib treatment: influence of miR-212 and miR-328 on ABCG2 expression.
Pharmacogenetics and genomics 2012;22(3):198-205.
2012: Ruwen Böhm; Ingolf Cascorbi; Jan Höcker; Thomas Herdegen
OpenVigil--free eyeballs on AERS pharmacovigilance data.
Nature biotechnology 2012;30(2):137-8.
2011: Mike Ufer; Celina von Stülpnagel; Sierk Haenisch; Gerhard Kluger; Amani Majed; Hiltrud Muhle; Herbert Plischke; Cornelia Remmler; Ulrich Stephani; Ingolf Cascorbi
Impact of ABCC2 genotype on antiepileptic drug response in Caucasian patients with childhood epilepsy.
Pharmacogenetics and genomics 2011;21(10):624-30.
2011: Fatima Ghaddar; Ingolf Cascorbi; Nathalie K Zgheib
Clinical implementation of pharmacogenetics: a nonrepresentative explorative survey to participants of WorldPharma 2010.
Pharmacogenomics 2011;12(7):1051-9.
2011: Maria C Athanasiou; Michael Dettling; Ingolf Cascorbi; Igor Mosyagin; Benjamin A Salisbury; Kerri A Pierz; Wei Zou; Heidi Whalen; Anil Malhotra; Todd Lencz; Stanton L Gerson; John M Kane; Carol R Reed
Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis.
The Journal of clinical psychiatry 2011;72(4):458-63.
2011: S Laechelt; E Turrini; A Ruehmkorf; Werner Siegmund; Ingolf Cascorbi; Sierk Haenisch
Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function.
The pharmacogenomics journal 2011;11(1):25-34.
2011: Oliver Bruhn; Ingolf Cascorbi; Joachim Grötzinger; Sascha Jung
Antimicrobial peptides and proteins of the horse - insights into a well-armed organism.
Veterinary research 2011;42(1):98.
2011: Andreas Binder; Denisa May; Ralf Baron; Christoph Maier; Thomas R Tölle; Rolf-Detlef Treede; Achim Berthele; Frank Faltraco; Herta Flor; Janne Gierthmühlen; Sierk Haenisch; Volker Huge; Walter Magerl; Christian Maihöfner; Helmut Richter; Roman Rolke; Andrea Scherens; Nurcan Üçeyler; Mike Ufer; Gunnar Wasner; Jihong Zhu; Ingolf Cascorbi
Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients.
PloS one 2011;6(3):e17387.
2011: Ingolf Cascorbi
P-glycoprotein: tissue distribution, substrates, and functional consequences of genetic variations.
Handbook of experimental pharmacology 2011;(201):261-83.
2010: Tilo Andus; Andreas Kocjan; Moritz Müser; Andrey Baranovsky; Tatyana L Mikhailova; Tatyana D Zvyagintseva; Andrey E Dorofeyev; Yurii S Lozynskyy; Ingolf Cascorbi; Manfred Stolte; Michael Vieth; Karin Dilger; Ralf Mohrbacher; Roland Greinwald
Clinical trial: a novel high-dose 1 g mesalamine suppository (Salofalk) once daily is as efficacious as a 500-mg suppository thrice daily in active ulcerative proctitis.
Inflammatory bowel diseases 2010;16(11):1947-56.
2010: Ingolf Cascorbi
Safe and effective medicines for all: is personalized medicine the answer?
Expert review of clinical pharmacology 2010;3(5):627-37.
2010: Ingolf Cascorbi
The promises of personalized medicine.
European journal of clinical pharmacology 2010;66(8):749-54.
2010: Donald Birkett; Kim Brøsen; Ingolf Cascorbi; Lars L Gustafsson; Simon Maxwell; Lembit Rago; Michael Rawlins; Marcus Reidenberg; Folke Sjöqvist; Tony Smith; Petra Thuerman; Andrew Walubo; Michael Orme; Folke Sjöqvist
Clinical pharmacology in research, teaching and health care: Considerations by IUPHAR, the International Union of Basic and Clinical Pharmacology.
Basic & clinical pharmacology & toxicology 2010;107(1):531-59.
2010: Nasir Ali Afsar; Sierk Haenisch; Ahmed Mateen; Ahmed Usman; Mike Ufer; Khwaja Zafar Ahmed; Hakimuddin Razi Ahmad; Ingolf Cascorbi
Genotype frequencies of selected drug metabolizing enzymes and ABC drug transporters among breast cancer patients on FAC chemotherapy.
Basic & clinical pharmacology & toxicology 2010;107(1):570-6.
2010: Mordechai Muszkat; Omer Bialer; Simcha Blotnick; Liat Adar; Hong-Guang Xie; Mike Ufer; Ingolf Cascorbi; Yoseph Caraco
Effects of folic acid supplementation on the pharmacokinetics and anticoagulant effect of warfarin: an open-label, prospective study of long-term administration in adults.
Clinical therapeutics 2010;32(2):347-56.
2010: Ingolf Cascorbi
ABC transporters in drug-refractory epilepsy: limited clinical significance of pharmacogenetics?
Clinical pharmacology and therapeutics 2010;87(1):15-8.
2010: Ingolf Cascorbi; Sierk Haenisch
Pharmacogenetics of ATP-binding cassette transporters and clinical implications.
Methods in molecular biology (Clifton, N.J.) 2010;596():95-121.
2009: Ruwen Böhm; Ingolf Cascorbi; Thomas Herdegen
[Hypoglycemic risk of insulinotropic drugs].
Medizinische Monatsschrift für Pharmazeuten 2009;32(12):453-8.
2009: Mike Ufer; Robert Häsler; Gunnar Jacobs; Sierk Haenisch; Sandra Lächelt; Frank Faltraco; Christian Sina; Philip Rosenstiel; Susanna Nikolaus; Stefan Schreiber; Ingolf Cascorbi
Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.
Pharmacogenomics 2009;10(12):1941-53.
2009: Rianne M F van Schie; Ingolf Cascorbi; Anke Hilse Maitland-van der Zee
Conference Scene: Pharmacogenomics at the second PharmSciFair 2009: adverse drug reactions and clinical implementation.
Pharmacogenomics 2009;10(9):1389-91.
2009: Mike Ufer; Igor Mosyagin; Hiltrud Muhle; Thies Jacobsen; Sierk Haenisch; Robert Häsler; Frank Faltraco; Cornelia Remmler; Sarah von Spiczak; Heyo K Kroemer; Uwe Runge; Rainer Boor; Ulrich Stephani; Ingolf Cascorbi
Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy.
Pharmacogenetics and genomics 2009;19(5):353-62.
2008: Igor Mosyagin; Uwe Runge; Henry W Schroeder; Eike Dazert; Silke Vogelgesang; Werner Siegmund; Rolf Warzok; Ingolf Cascorbi
Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients.
Epilepsia 2008;49(9):1555-61.
2008: Mike Ufer; K Dilger; L Leschhorn; Lm Daufresne; I Mosyagin; Philip Rosenstiel; R Haesler; T Kuehbacher; S Nikolaus; Stefan Schreiber; Ingolf Cascorbi
Influence of CYP3A4, CYP3A5, and ABCB1 genotype and expression on budesonide pharmacokinetics: a possible role of intestinal CYP3A4 expression.
Clinical pharmacology and therapeutics 2008;84(1):43-6.
2008: Sierk Haenisch; Karen May; Danilo Wegner; Amke Caliebe; Ingolf Cascorbi; Werner Siegmund
Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol.
Pharmacogenetics and genomics 2008;18(4):357-65.
2008: Cornelia Remmler; Ingolf Cascorbi
Pharmacogenomics in acute coronary syndrome.
Expert opinion on pharmacotherapy 2008;9(3):363-76.
2007: Simon R J Maxwell; Ingolf Cascorbi; Michael Orme; David J Webb
Educating European (junior) doctors for safe prescribing.
Basic & clinical pharmacology & toxicology 2007;101(6):395-400.
2007: Diana Kuhnke; Gabriele Jedlitschky; Markus Grube; Markus Krohn; Mathias Jucker; Igor Mosyagin; Ingolf Cascorbi; Lary Walker; Heyo K Kroemer; Rolf Warzok; Silke Vogelgesang
MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier.
Brain pathology (Zurich, Switzerland) 2007;17(4):347-53.
2007: Michael Dettling; Ingolf Cascorbi; Carolin Opgen-Rhein; R Schaub
Clozapine-induced agranulocytosis in schizophrenic Caucasians: confirming clues for associations with human leukocyte class I and II antigens.
The pharmacogenomics journal 2007;7(5):325-32.
2007: Karin Dilger; Dietmar Trenk; Martin Rössle; M Cap; A Zähringer; V Wacheck; C Remmler; Ingolf Cascorbi; Wolfgang Kreisel; G Novacek
A clinical trial on absorption and N-acetylation of oral and rectal mesalazine.
European journal of clinical investigation 2007;37(7):558-65.
2007: Emanuela Taioli; Simone Benhamou; Christine Bouchardy; Ingolf Cascorbi; Nohelia Cajas-Salazar; Heike Dally; Kwun M Fong; Jill Everland Larsen; Loïc Le Marchand; Stephanie J London; Angela Risch; Margaret R Spitz; Isabelle Stucker; Brian Weinshenker; Xifeng Wu; Ping Yang
Myeloperoxidase G-463A polymorphism and lung cancer: a HuGE genetic susceptibility to environmental carcinogens pooled analysis.
Genetics in medicine : official journal of the American College of Medical Genetics 2007;9(2):67-73.
2007: Lutz Renders; M Frisman; M Ufer; Igor Mosyagin; Sierk Haenisch; U Ott; A Caliebe; M Dechant; F Braun; Ulrich Kunzendorf; Ingolf Cascorbi
CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients.
Clinical pharmacology and therapeutics 2007;81(2):228-34.
2007: Sierk Haenisch; U Zimmermann; Eike Dazert; Christoph J Wruck; Peter Dazert; Werner Siegmund; S Siegmund; Heyo K Kroemer; Rolf Warzok; Ingolf Cascorbi
Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex.
The pharmacogenomics journal 2007;7(1):56-65.
2007: Katrin Bühler; Mike Ufer; Alexis Müller-Marbach; Ulrich Brinkmann; Michael Laule; Verena Stangl; Ivar Roots; Karl Stangl; Ingolf Cascorbi
Risk of coronary artery disease as influenced by variants of the human endothelin and endothelin-converting enzyme genes.
Pharmacogenetics and genomics 2007;17(1):77-83.
2007: Ivar Roots; Gabriele Laschinski; Farhad Arjomand Nahad; Julia Kirchheiner; Dieter Schwarz; Jürgen Brockmöller; Ingolf Cascorbi; Thomas Gerloff
Genotype and phenotype relationship in drug metabolism.
Ernst Schering Research Foundation workshop 2007;(59):81-100.
2006: Ingolf Cascorbi
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.
Pharmacology & therapeutics 2006;112(2):457-73.
2006: Karin Dilger; Ingolf Cascorbi; Frank Grünhage; Simon Hohenester; Tilman Sauerbruch; Ulrich Beuers
Multidrug resistance 1 genotype and disposition of budesonide in early primary biliary cirrhosis.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(3):285-90.
2006: Annika Bernsdorf; Thomas Giessmann; Christiane Modess; Danilo Wegner; Stefanie Igelbrink; Ute Hecker; Sierk Haenisch; Ingolf Cascorbi; Bernd Terhaag; Werner Siegmund
Simvastatin does not influence the intestinal P-glycoprotein and MPR2, and the disposition of talinolol after chronic medication in healthy subjects genotyped for the ABCB1, ABCC2 and SLCO1B1 polymorphisms.
British journal of clinical pharmacology 2006;61(4):440-50.
2006: Ingolf Cascorbi
Genetic basis of toxic reactions to drugs and chemicals.
Toxicology letters 2006;162(1):16-28.
2006: Stefan Oswald; Sierk Haenisch; Christiane Fricke; Thomas Sudhop; Cornelia Remmler; Thomas Giessmann; Gabriele Jedlitschky; Ulrike Adam; Eike Dazert; Rolf Warzok; Wolfram Wacke; Ingolf Cascorbi; Heyo K Kroemer; Werner Weitschies; Klaus Von Bergmann; Werner Siegmund
Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans.
Clinical pharmacology and therapeutics 2006;79(3):206-17.
2006: Konrad Meissner; Björn Heydrich; Gabriele Jedlitschky; Henriette Meyer zu Schwabedissen; Igor Mosyagin; Peter Dazert; Lothar Eckel; Silke Vogelgesang; Rolf Warzok; Michael Böhm; Christian Lehmann; Michael Wendt; Ingolf Cascorbi; Heyo K Kroemer
The ATP-binding cassette transporter ABCG2 (BCRP), a marker for side population stem cells, is expressed in human heart.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(2):215-21.
2006: Stefan Oswald; Eberhard Scheuch; Ingolf Cascorbi; Werner Siegmund
A LC-MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;830(1):143-50.
2005: Matthias Gratz; Christiane Kunert-Keil; Ulrich John; Ingolf Cascorbi; Heyo K Kroemer
Identification and functional analysis of genetic variants of the human beta-glucuronidase in a German population sample.
Pharmacogenetics and genomics 2005;15(12):875-81.
2005: Emily M Garland; Robert Winker; scott williams; Lan Jiang; Krista Stanton; Daniel W Byrne; Italo Biaggioni; Ingolf Cascorbi; John A Phillips; Paul A Harris; Hugo W Rüdiger; David Robertson
Endothelial NO synthase polymorphisms and postural tachycardia syndrome.
Hypertension 2005;46(5):1103-10.
2005: Birger Wolff; Claudia Braun; Christina Schlüter; Hans Joergen Grabe; Katrin Popowski; Henry Völzke; Jan Lüdemann; Ulrich John; Ingolf Cascorbi
Endothelial nitric oxide synthase Glu(298)-->Asp polymorphism, carotid atherosclerosis and intima-media thickness in a general population sample.
Clinical science (London, England : 1979) 2005;109(5):475-81.
2005: Robert Winker; Emily M Garland; Hugo W Rüdiger; André Diedrich; Italo Biaggioni; Ivo Ponocny; Ingolf Cascorbi; David Robertson
Influence of an insertion variant in the 5'UTR of the endothelin-1 gene on orthostatic intolerance.
The American journal of the medical sciences 2005;330(4):166-71.
2005: Igor Mosyagin; Ingolf Cascorbi; Rainer Schaub; Timo Krüger; Michael Dettling
Drug-induced agranulocytosis: impact of different fcgamma receptor polymorphisms?
Journal of clinical psychopharmacology 2005;25(5):435-40.
2005: Birger Wolff; Hans Joergen Grabe; Christina Schlüter; Katrin Popowski; Henry Völzke; Jan Lüdemann; Ulrich John; Stephan B Felix; Ingolf Cascorbi
Endothelial nitric oxide synthase Glu298Asp gene polymorphism, blood pressure and hypertension in a general population sample.
Journal of hypertension 2005;23(7):1361-6.
2005: Henriette Meyer zu Schwabedissen; Gabriele Jedlitschky; Matthias Gratz; Sierk Haenisch; Knud Linnemann; Christoph Fusch; Ingolf Cascorbi; Heyo K Kroemer
Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(7):896-904.
2005: Martina Kinzig; Dorota Tomalik-Scharte; Alexander Jetter; Bernhard Scheidel; Verena Jakob; Michael Rodamer; Ingolf Cascorbi; Oxana Doroshyenko; Fritz Sörgel; Uwe Fuhr
Should we use N-acetyltransferase type 2 genotyping to personalize isoniazid doses?
Antimicrobial agents and chemotherapy 2005;49(5):1733-8.
2005: Evgeniya V Belogubova; Ekaterina Kuligina; Alexandr V Togo; Maria B Karpova; Julia M Ulibina; Vladimir A Shutkin; Kaido P Hanson; Katrin Popowski; Igor Mosyagin; Ingolf Cascorbi; Ari Hirvonen; Evgeny N Imyanitov
'Comparison of extremes' approach provides evidence against the modifying role of NAT2 polymorphism in lung cancer susceptibility.
Cancer letters 2005;221(2):177-83.
2005: Ramona Timm; R Kaiser; J Lötsch; U Heider; O Sezer; Klaus Weisz; M Montemurro; Ivar Roots; Ingolf Cascorbi
Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19.
The pharmacogenomics journal 2005;5(6):365-73.
2005: Birger Wolff; Hans Joergen Grabe; Henry Völzke; Jan Lüdemann; Christian Schwahn; Harald J Freyberger; Ulrich John; Martina Lange; Ingolf Cascorbi; Stephan B Felix
A functional serotonin transporter (SLC6A4) polymorphism modifies the association of smoking and diabetes with asymptomatic carotid atherosclerosis.
Thrombosis and haemostasis 2005;93(1):180-2.
2004: Igor Mosyagin; Michael Dettling; Ivar Roots; Bruno Mueller-Oerlinghausen; Ingolf Cascorbi
Impact of myeloperoxidase and NADPH-oxidase polymorphisms in drug-induced agranulocytosis.
Journal of clinical psychopharmacology 2004;24(6):613-7.
2004: Sandra Bien; Christoph A Ritter; M Kranz; Christian Scharf; Leif Steil; M Hummel; Uwe Völker; Ingolf Cascorbi; Heyo K Kroemer
Influence of doxorubicin on gene expression and protein pattern in HeLa cells.
International journal of clinical pharmacology and therapeutics 2004;42(11):640-1.
2004: Ivar Roots; Thomas Gerloff; Christian Meisel; Julia Kirchheiner; Mark Goldammer; Rolf Kaiser; Gabriele Laschinski; Jürgen Brockmöller; Ingolf Cascorbi; Ullrich Kleeberg; Alfred G Hildebrandt
Pharmacogenetics-based new therapeutic concepts.
Drug metabolism reviews 2004;36(3-4):617-38.
2004: Ingolf Cascorbi; Martin Paul; Heyo K Kroemer
Pharmacogenomics of heart failure -- focus on drug disposition and action.
Cardiovascular research 2004;64(1):32-9.
2004: Silke Vogelgesang; Christiane Kunert-Keil; Ingolf Cascorbi; Igor Mosyagin; E Schröder; Uwe Runge; Gabriele Jedlitschky; Heyo K Kroemer; Joachim Oertel; Michael R Gaab; Jens Pahnke; Lary Walker; Rolf Warzok
Expression of multidrug transporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy.
Clinical neuropathology 2004;23(5):223-31.
2004: Thomas Giessmann; Karen May; Christiane Modess; Danilo Wegner; Ute Hecker; Michael Zschiesche; Peter Dazert; Markus Grube; Eike Schroeder; Rolf Warzok; Ingolf Cascorbi; Heyo K Kroemer; Werner Siegmund
Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.
Clinical pharmacology and therapeutics 2004;76(3):192-200.
2004: Konrad Meissner; Gabriele Jedlitschky; Henriette Meyer zu Schwabedissen; Peter Dazert; Lothar Eckel; Silke Vogelgesang; Rolf Warzok; Michael Böhm; Christian Lehmann; Michael Wendt; Ingolf Cascorbi; Heyo K Kroemer
Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms.
Pharmacogenetics 2004;14(6):381-5.
2004: Silke Vogelgesang; Rolf Warzok; Ingolf Cascorbi; Christiane Kunert-Keil; Eike Schroeder; Heyo K Kroemer; Werner Siegmund; Lary Walker; Jens Pahnke
The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease.
Current Alzheimer research 2004;1(2):121-5.
2004: Margarita Rojas; Béatrice Marie; Jean-Michel Vignaud; Nadine Martinet; Joëlle Siat; Gilles Grosdidier; Ingolf Cascorbi; Kroum Alexandrov
High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma.
Cancer letters 2004;207(2):157-63.
2004: Thomas Giessmann; Christiane Modess; Ute Hecker; Michael Zschiesche; Peter Dazert; Christiane Kunert-Keil; Rolf Warzok; Georg Engel; Werner Weitschies; Ingolf Cascorbi; Heyo K Kroemer; Werner Siegmund
CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects.
Clinical pharmacology and therapeutics 2004;75(3):213-22.
2004: Alexander Jetter; Martina Kinzig; Michael Illauer; Robert Hermann; Katharina Erb; Jürgen Borlak; Helga Wolf; Gillian Smith; Ingolf Cascorbi; Fritz Sörgel; Uwe Fuhr
Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure.
European journal of clinical pharmacology 2004;60(1):17-21.
2004: A Lazar; H Menzel; Ingolf Cascorbi; G Kümel; M Sachs; Stephan Rietbrock; Ivar Roots; Uwe Fuhr
CYP1A1 alleles in women with focal nodular hyperplasia of the liver (FNH).
International journal of clinical pharmacology and therapeutics 2004;42(2):78-82.
2004: Konstanze Diefenbach; Farhad Arjomand Nahad; Christian Meisel; Ingo Fietze; Ingolf Cascorbi; Karl Stangl; Olfert Landt; Reinhold Kerb; Ulrich Brinkmann; Ivar Roots
Identification of twelve polymorphisms in the endothelin-1 gene by use of fluorescently labeled oligonucleotides and PCR with restriction fragment polymorphism analysis.
Clinical chemistry 2004;50(2):448-51.
2004: Matthias Vogel; Silvia Pfeifer; Rainer T Schaub; Hans Joergen Grabe; Sven Barnow; Harald J Freyberger; Ingolf Cascorbi
Decreased levels of dopamine D3 receptor mRNA in schizophrenic and bipolar patients.
Neuropsychobiology 2004;50(4):305-10.
2003: Mia Hashibe; Paul Brennan; Richard C Strange; Rajani A Bhisey; Ingolf Cascorbi; Philip Lazarus; Michael B Oude Ophuis; Simone Benhamou; William D Foulkes; Takahiko Katoh; Christiane Coutelle; Marjorie Romkes; Laura Gaspari; Emanuela Taioli; Paolo Boffetta
Meta- and pooled analyses of GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes and risk of head and neck cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(12):1509-17.
2003: Ingolf Cascorbi
Pharmacogenetics of cytochrome p4502D6: genetic background and clinical implication.
European journal of clinical investigation 2003;33 Suppl 2():17-22.
2003: Peter Dazert; Konrad Meissner; Silke Vogelgesang; Björn Heydrich; Lothar Eckel; Michael Böhm; Rolf Warzok; Reinhold Kerb; Ulrich Brinkmann; Elke Schaeffeler; Matthias Schwab; Ingolf Cascorbi; Gabriele Jedlitschky; Heyo K Kroemer
Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart.
The American journal of pathology 2003;163(4):1567-77.
2003: Kivanc Güngör; Mehtap Ozkur; Ingolf Cascorbi; Jürgen Brockmöller; Necdet A Bekir; Ivar Roots; A Sükrü Aynacioglu
Beta 2-adrenergic receptor polymorphism and susceptibility to primary congenital and primary open angle glaucoma.
European journal of clinical pharmacology 2003;59(7):527-31.
2003: Katrin Popowski; Bernhard Sperker; Heyo K Kroemer; Ulrich John; Michael Laule; Karl Stangl; Ingolf Cascorbi
Functional significance of a hereditary adenine insertion variant in the 5'-UTR of the endothelin-1 gene.
Pharmacogenetics 2003;13(8):445-51.
2003: Elena Gaikovitch; Ingolf Cascorbi; Przemyslaw M Mrozikiewicz; Jürgen Brockmöller; Roland Frötschl; Karla Köpke; Thomas Gerloff; Jury N Chernov; Ivar Roots
Polymorphisms of drug-metabolizing enzymes CYP2C9, CYP2C19, CYP2D6, CYP1A1, NAT2 and of P-glycoprotein in a Russian population.
European journal of clinical pharmacology 2003;59(4):303-12.
2003: Loïc Le Marchand; Chuanfa Guo; Simone Benhamou; Christine Bouchardy; Ingolf Cascorbi; Margie L Clapper; Seymour Garte; Aage Haugen; Magnus Ingelman-Sundberg; Masahiro Kihara; Agneta Rannug; David Ryberg; Isabelle Stücker; Haruhiko Sugimura; Emanuela Taioli
Pooled analysis of the CYP1A1 exon 7 polymorphism and lung cancer (United States).
Cancer causes & control : CCC 2003;14(4):339-46.
2003: Rayjean J Hung; Paolo Boffetta; Jürgen Brockmöller; Dorota Butkiewicz; Ingolf Cascorbi; Margie L Clapper; Seymour Garte; Aage Haugen; Ari Hirvonen; Sisko Anttila; Ivan Kalina; Loïc Le Marchand; Stephanie J London; Agneta Rannug; Marjorie Romkes; Ján Salagovic; Bernadette Schoket; Laura Gaspari; Emanuela Taioli
CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis.
Carcinogenesis 2003;24(5):875-82.
2003: Michael Laule; Christian Meisel; Ines Prauka; Ingolf Cascorbi; Uwe Malzahn; Stephan B Felix; Gert Baumann; Ivar Roots; Karl Stangl; Verena Stangl
Interaction of CA repeat polymorphism of the endothelial nitric oxide synthase and hyperhomocysteinemia in acute coronary syndromes: evidence of gender-specific differences.
Journal of molecular medicine (Berlin, Germany) 2003;81(5):305-9.
2003: Paolo Vineis; Fabrizio Veglia; Simone Benhamou; Dorota Butkiewicz; Ingolf Cascorbi; Margie L Clapper; Vita Dolzan; Aage Haugen; Ari Hirvonen; Magnus Ingelman-Sundberg; Masahiro Kihara; Chikako Kiyohara; Pierre Kremers; Loïc Le Marchand; Susumu Ohshima; Roberta Pastorelli; Agneta Rannug; Marjorie Romkes; Bernadette Schoket; Peter Shields; Richard C Strange; Isabelle Stucker; Haruhiko Sugimura; Seymour Garte; Laura Gaspari; Emanuela Taioli
CYP1A1 T3801 C polymorphism and lung cancer: a pooled analysis of 2451 cases and 3358 controls.
International journal of cancer. Journal international du cancer 2003;104(5):650-7.
2003: Emanuela Taioli; Laura Gaspari; Simone Benhamou; Paolo Boffetta; J Brockmoller; Dorota Butkiewicz; Ingolf Cascorbi; Margie L Clapper; Vita Dolzan; Aage Haugen; Ari Hirvonen; Kirsti Husgafvel-Pursiainen; Ivan Kalina; Pierre Kremers; Loïc Le Marchand; S London; Agneta Rannug; Marjorie Romkes; Bernadette Schoket; janeric seidegard; Richard C Strange; Isabelle Stucker; Jordi To-Figueras; Seymour Garte
Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years.
International journal of epidemiology 2003;32(1):60-3.
2003: Werner Siegmund; Ingolf Cascorbi; Werner Weitschies; Heyo K Kroemer
[Significance of drug transporter for the internal medicine clinic].
Der Internist 2003;44(2):219-26.
2003: Matthias Schwab; Elke Schaeffeler; Claudia Marx; Martin F Fromm; Bernd A Kaskas; Joerg Metzler; Eduard F Stange; Hans Herfarth; Juergen Schoelmerich; Michael Gregor; Siegfried Walker; Ingolf Cascorbi; Ivar Roots; Ulrich Brinkmann; Uli Zanger; Michel Eichelbaum
Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis.
Gastroenterology 2003;124(1):26-33.
2002: Kroum Alexandrov; Ingolf Cascorbi; Margarita Rojas; Guy Bouvier; Erik Kriek; Helmut Bartsch
CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation.
Carcinogenesis 2002;23(12):1969-77.
2002: Muradiye Nacak; A Sükrü Aynacioglu; Ayten Filiz; Ingolf Cascorbi; M Emin Erdal; Necat Yilmaz; Erhan Ekinci; Ivar Roots
Association between the N-acetylation genetic polymorphism and bronchial asthma.
British journal of clinical pharmacology 2002;54(6):671-4.
2002: Thomas Gerloff; Melanie Schaefer; Andreas Johne; Kersti Oselin; Christian Meisel; Ingolf Cascorbi; Ivar Roots
MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males.
British journal of clinical pharmacology 2002;54(6):610-6.
2002: Andreas Johne; Karla Köpke; Thomas Gerloff; Ingrid Mai; Stephan Rietbrock; Christian Meisel; Sven Hoffmeyer; Reinhold Kerb; Martin F Fromm; Ulrich Brinkmann; Michel Eichelbaum; Jürgen Brockmöller; Ingolf Cascorbi; Ivar Roots
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene.
Clinical pharmacology and therapeutics 2002;72(5):584-94.
2002: Werner Siegmund; Karen Ludwig; Thomas Giessmann; Peter Dazert; Eike Schroeder; Bernhard Sperker; Rolf Warzok; Heyo K Kroemer; Ingolf Cascorbi
The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.
Clinical pharmacology and therapeutics 2002;72(5):572-83.
2002: Konrad Meissner; Bernhard Sperker; Christiane Karsten; Henriette Meyer Zu Schwabedissen; Ute Seeland; Michael Böhm; Sandra Bien; Peter Dazert; Christiane Kunert-Keil; Silke Vogelgesang; Rolf Warzok; Werner Siegmund; Ingolf Cascorbi; Michael Wendt; Heyo K Kroemer
Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(10):1351-6.
2002: Petra Zschieschang; Falk Hiepe; Erika Gromnica-Ihle; Ivar Roots; Ingolf Cascorbi
Lack of association between arylamine N-acetyltransferase 2 (NAT2) polymorphism and systemic lupus erythematosus.
Pharmacogenetics 2002;12(7):559-63.
2002: Silke Vogelgesang; Ingolf Cascorbi; Eike Schroeder; Jens Pahnke; Heyo K Kroemer; Werner Siegmund; Christiane Kunert-Keil; Lary Walker; Rolf Warzok
Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.
Pharmacogenetics 2002;12(7):535-41.
2002: Mikko Niemi; Ingolf Cascorbi; Ramona Timm; Heyo K Kroemer; Pertti J Neuvonen; Kari T Kivistö
Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes.
Clinical pharmacology and therapeutics 2002;72(3):326-32.
2002: Werner Siegmund; Stephan Altmannsberger; Andrea Paneitz; Ute Hecker; Michael Zschiesche; Gerd Franke; Wieland Meng; Rolf Warzok; Eike Schroeder; Bernhard Sperker; Bernd Terhaag; Ingolf Cascorbi; Heyo K Kroemer
Effect of levothyroxine administration on intestinal P-glycoprotein expression: consequences for drug disposition.
Clinical pharmacology and therapeutics 2002;72(3):256-64.
2002: Peter Meisel; Jürgen Giebel; M Peters; K Foerster; Ingolf Cascorbi; Karin Wulff; Jutta Fanghaenel; Thomas Kocher
Expression of N-acetyltransferases in periodontal granulation tissue.
Journal of dental research 2002;81(5):349-53.
2002: Ingolf Cascorbi
[Status of pharmacogenomics and its future role in drug therapy].
Der Internist 2002;43(4):506-10.
2002: Peter Meisel; T Krause; Ingolf Cascorbi; W Schroeder; F Herrmann; U John; Thomas Kocher
Gender and smoking-related risk reduction of periodontal disease with variant myeloperoxidase alleles.
Genes and immunity 2002;3(2):102-6.
2001: Ingolf Cascorbi; Ivar Roots; Jürgen Brockmöller
Association of NAT1 and NAT2 polymorphisms to urinary bladder cancer: significantly reduced risk in subjects with NAT1*10.
Cancer research 2001;61(13):5051-6.
2001: Margarita Rojas; Roger Godschalk; Kroum Alexandrov; Ingolf Cascorbi; Erik Kriek; Judith U Ostertag; Frederik J Van Schooten; Helmut Bartsch
Myeloperoxidase--463A variant reduces benzo[a]pyrene diol epoxide DNA adducts in skin of coal tar treated patients.
Carcinogenesis 2001;22(7):1015-8.
2001: Dieter Schwarz; Pyotr Kisselev; Horst Honeck; Ingolf Cascorbi; Wolf-Hagen Schunck; Ivar Roots
Co-expression of human cytochrome P4501A1 (CYP1A1) variants and human NADPH-cytochrome P450 reductase in the baculovirus/insect cell system.
Xenobiotica; the fate of foreign compounds in biological systems 2001;31(6):345-56.
2001: Michael Dettling; R T Schaub; Bruno Mueller-Oerlinghausen; Ivar Roots; Ingolf Cascorbi
Further evidence of human leukocyte antigen-encoded susceptibility to clozapine-induced agranulocytosis independent of ancestry.
Pharmacogenetics 2001;11(2):135-41.
2001: Ingolf Cascorbi; Thomas Gerloff; Andreas Johne; Christian Meisel; Sven Hoffmeyer; M Schwab; Elke Schaeffeler; Michel Eichelbaum; Ulrich Brinkmann; Ivar Roots
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.
Clinical pharmacology and therapeutics 2001;69(3):169-74.
2001: Dieter Schwarz; Pyotr Kisselev; Ingolf Cascorbi; Wolf-Hagen Schunck; Ivar Roots
Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants.
Carcinogenesis 2001;22(3):453-9.
2001: Michael Dettling; Ingolf Cascorbi; Ivar Roots; Bruno Mueller-Oerlinghausen
Genetic determinants of clozapine-induced agranulocytosis: recent results of HLA subtyping in a non-jewish caucasian sample.
Archives of general psychiatry 2001;58(1):93-4.
2000: Michael Dettling; Christoph Sachse; Bruno Müller-Oerlinghausen; Ivar Roots; Jürgen Brockmöller; A Rolfs; Ingolf Cascorbi
Clozapine-induced agranulocytosis and hereditary polymorphisms of clozapine metabolizing enzymes: no association with myeloperoxidase and cytochrome P4502D6.
Pharmacopsychiatry 2000;33(6):218-20.
2000: Karl Stangl; Ingolf Cascorbi; Verena Stangl; Michael Laule; Thomas Dschietzig; Christoph Richter; Stephan B Felix; Ivar Roots; Gert Baumann
Hyperhomocysteinaemia and adverse events complicating coronary catheter interventions.
International journal of cardiology 2000;76(2-3):211-7.
2000: Przemyslaw M Mrozikiewicz; Ingolf Cascorbi; Sabine Ziemer; Michael Laule; Christian Meisel; Verena Stangl; Wolfgang Rutsch; Klaus-Dieter Wernecke; G Baumann; Ivar Roots; K Stangl
Reduced procedural risk for coronary catheter interventions in carriers of the coagulation factor VII-Gln353 gene.
Journal of the American College of Cardiology 2000;36(5):1520-5.
2000: Christian Meisel; Ivar Roots; Ingolf Cascorbi; U Brinkmann; Jürgen Brockmöller
How to manage individualized drug therapy: application of pharmacogenetic knowledge of drug metabolism and transport.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(9):869-76.
2000: Dieter Schwarz; Pyotr Kisselev; Wolf-Hagen Schunck; Alexey Chernogolov; W Boidol; Ingolf Cascorbi; Ivar Roots
Allelic variants of human cytochrome P450 1A1 (CYP1A1): effect of T461N and I462V substitutions on steroid hydroxylase specificity.
Pharmacogenetics 2000;10(6):519-30.
2000: Karl Stangl; Ingolf Cascorbi; Michael Laule; T Klein; Verena Stangl; S Rost; K D Wernecke; Stephan B Felix; Albrecht Bindereif; G Baumann; Ivar Roots
High CA repeat numbers in intron 13 of the endothelial nitric oxide synthase gene and increased risk of coronary artery disease.
Pharmacogenetics 2000;10(2):133-40.
2000: Ingolf Cascorbi; S Henning; Jürgen Brockmöller; J Gephart; C Meisel; J M Müller; R Loddenkemper; Ivar Roots
Substantially reduced risk of cancer of the aerodigestive tract in subjects with variant--463A of the myeloperoxidase gene.
Cancer research 2000;60(3):644-9.
2000: Margarita Rojas; Ingolf Cascorbi; Kroum Alexandrov; Erik Kriek; G Auburtin; L Mayer; Annette Kopp-Schneider; I Roots; Helmut Bartsch
Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism.
Carcinogenesis 2000;21(1):35-41.
1999: Ingolf Cascorbi; Michael Laule; Przemyslaw M Mrozikiewicz; A Mrozikiewicz; C Andel; G Baumann; Ivar Roots; K Stangl
Mutations in the human paraoxonase 1 gene: frequencies, allelic linkages, and association with coronary artery disease.
Pharmacogenetics 1999;9(6):755-61.
1999: C Bruhn; Jürgen Brockmöller; Ingolf Cascorbi; Ivar Roots; Hans-Hubert Borchert
Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1).
Biochemical pharmacology 1999;58(11):1759-64.
1999: A Sükrü Aynacioglu; Ingolf Cascorbi; Kivanc Güngör; Mehtap Ozkur; Necdet A Bekir; Ivar Roots; Jürgen Brockmöller
Population frequency, mutation linkage and analytical methodology for the Arg16Gly, Gln27Glu and Thr164Ile polymorphisms in the beta2-adrenergic receptor among Turks.
British journal of clinical pharmacology 1999;48(5):761-4.
1999: A Sükrü Aynacioglu; Ingolf Cascorbi; Przemyslaw M Mrozikiewicz; Muradiye Nacak; E E Tapanyigit; Ivar Roots
Paraoxonase 1 mutations in a Turkish population.
Toxicology and applied pharmacology 1999;157(3):174-7.
1999: Michael Dettling; Ingolf Cascorbi; R Hellweg; U Deicke; L Weise; Bruno Müller-Oerlinghausen
Genetic determinants of drug-induced agranulocytosis: potential risk of olanzapine?
Pharmacopsychiatry 1999;32(3):110-2.
1999: Ingolf Cascorbi; Jürgen Brockmöller; Przemyslaw M Mrozikiewicz; A Müller; Ivar Roots
Arylamine N-acetyltransferase activity in man.
Drug metabolism reviews 1999;31(2):489-502.
1999: Michael Laule; Ingolf Cascorbi; Verena Stangl; C Bielecke; Klaus-Dieter Wernecke; Przemyslaw M Mrozikiewicz; Stephan B Felix; Ivar Roots; Gert Baumann; Karl Stangl
A1/A2 polymorphism of glycoprotein IIIa and association with excess procedural risk for coronary catheter interventions: a case-controlled study.
Lancet 1999;353(9154):708-12.
1999: Ingolf Cascorbi; Ivar Roots
Pitfalls in N-acetyltransferase 2 genotyping.
Pharmacogenetics 1999;9(1):123-7.
1998: Jürgen Brockmöller; Ingolf Cascorbi; Reinhold Kerb; Christoph Sachse; Ivar Roots
Polymorphisms in xenobiotic conjugation and disease predisposition.
Toxicology letters 1998;102-103():173-83.
1998: Margarita Rojas; Kroum Alexandrov; Ingolf Cascorbi; J Brockmöller; A Likhachev; K Pozharisski; Guy Bouvier; G Auburtin; L Mayer; Annette Kopp-Schneider; I Roots; Helmut Bartsch
High benzo[a]pyrene diol-epoxide DNA adduct levels in lung and blood cells from individuals with combined CYP1A1 MspI/Msp-GSTM1*0/*0 genotypes.
Pharmacogenetics 1998;8(2):109-18.
1998: A Sükrü Aynacioglu; Ingolf Cascorbi; Przemyslaw M Mrozikiewicz; Ivar Roots
High frequency of CYP1A1 mutations in a Turkish population.
Archives of toxicology 1998;72(4):215-8.
1997: A Sükrü Aynacioglu; Ingolf Cascorbi; Przemyslaw M Mrozikiewicz; Ivar Roots
Arylamine N-acetyltransferase (NAT2) genotypes in a Turkish population.
Pharmacogenetics 1997;7(4):327-31.
1997: Przemyslaw M Mrozikiewicz; Ingolf Cascorbi; Jürgen Brockmöller; Ivar Roots
CYP1A1 mutations 4887A, 4889G, 5639C and 6235C in the Polish population and their allelic linkage, determined by peptide nucleic acid-mediated PCR clamping.
Pharmacogenetics 1997;7(4):303-7.
1997: Przemyslaw M Mrozikiewicz; Olfert Landt; Ingolf Cascorbi; Ivar Roots
Peptide nucleic acid-mediated polymerase chain reaction clamping allows allelic allocation of CYP1A1 mutations.
Analytical biochemistry 1997;250(2):256-7.
1996: Jürgen Brockmöller; R Kaiser; Reinhold Kerb; Ingolf Cascorbi; V Jaeger; Ivar Roots
Polymorphic enzymes of xenobiotic metabolism as modulators of acquired P53 mutations in bladder cancer.
Pharmacogenetics 1996;6(6):535-45.
1996: Ingolf Cascorbi; Jürgen Brockmöller; Ivar Roots
A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility.
Cancer research 1996;56(21):4965-9.
1996: Ingolf Cascorbi; Jürgen Brockmöller; Przemyslaw M Mrozikiewicz; Steffen Bauer; R Loddenkemper; Ivar Roots
Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer.
Cancer research 1996;56(17):3961-6.
1996: Jürgen Brockmöller; Ingolf Cascorbi; Reinhold Kerb; Ivar Roots
Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk.
Cancer research 1996;56(17):3915-25.
1996: Ingolf Cascorbi; Jürgen Brockmöller; Steffen Bauer; T Reum; Ivar Roots
NAT2*12A (803A-->G) codes for rapid arylamine n-acetylation in humans.
Pharmacogenetics 1996;6(3):257-9.
1996: Przemyslaw M Mrozikiewicz; Ingolf Cascorbi; Jürgen Brockmöller; Ivar Roots
Determination and allelic allocation of seven nucleotide transitions within the arylamine N-acetyltransferase gene in the Polish population.
Clinical pharmacology and therapeutics 1996;59(4):376-82.
1995: Ingolf Cascorbi; N Drakoulis; Jürgen Brockmöller; A Maurer; K Sperling; Ivar Roots
Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity.
American journal of human genetics 1995;57(3):581-92.
1994: N Drakoulis; Ingolf Cascorbi; Jürgen Brockmöller; C R Gross; Ivar Roots
Polymorphisms in the human CYP1A1 gene as susceptibility factors for lung cancer: exon-7 mutation (4889 A to G), and a T to C mutation in the 3'-flanking region.
The Clinical investigator 1994;72(3):240-8.