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Ashraf S Ibrahim; Teclegiorgis Gebremariam; Guanpingsheng Luo; Yue Fu; Samuel W French; John Edwards; Brad Spellberg
Combination therapy of murine mucormycosis or aspergillosis with iron chelation, polyenes, and echinocandins.
Eric P Brass; John Edwards
Should the guidelines for management of central venous catheters in patients with candidemia be changed now?
Ashraf S Ibrahim; Teclegiorgis Gebremariam; Lin Lin; Guanpingsheng Luo; Mohamed I Husseiny; Christopher D Skory; Yue Fu; Samuel W French; John Edwards; Brad Spellberg
The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis.

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2011: Ashraf S Ibrahim; Teclegiorgis Gebremariam; Guanpingsheng Luo; Yue Fu; Samuel W French; John Edwards; Brad Spellberg
Combination therapy of murine mucormycosis or aspergillosis with iron chelation, polyenes, and echinocandins.
Antimicrobial agents and chemotherapy 2011;55(4):1768-70.
2010: Eric P Brass; John Edwards
Should the guidelines for management of central venous catheters in patients with candidemia be changed now?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010;51(3):304-6.
2010: Ashraf S Ibrahim; Teclegiorgis Gebremariam; Lin Lin; Guanpingsheng Luo; Mohamed I Husseiny; Christopher D Skory; Yue Fu; Samuel W French; John Edwards; Brad Spellberg
The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis.
Molecular microbiology 2010;77(3):587-604.
2010: Mingfu Liu; Brad Spellberg; Quynh T Phan; Yue Fu; Yong Fu; Amy S Lee; John Edwards; Scott Filler; Ashraf S Ibrahim
The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.
The Journal of clinical investigation 2010;120(6):1914-24.
2010: Beverlie Baquir; Lin Lin; Ashraf S Ibrahim; Yue Fu; Valentina Avanesian; Ang Tu; John Edwards; Brad Spellberg
Immunological reactivity of blood from healthy humans to the rAls3p-N vaccine protein.
The Journal of infectious diseases 2010;201(3):473-7.
2010: Ashraf S Ibrahim; Teclegiorgis Gebremariam; Samuel W French; John Edwards; Brad Spellberg
The iron chelator deferasirox enhances liposomal amphotericin B efficacy in treating murine invasive pulmonary aspergillosis.
The Journal of antimicrobial chemotherapy 2010;65(2):289-92.
2009: Lin Lin; Ashraf S Ibrahim; Xin Xu; Joshua M Farber; Valentina Avanesian; Beverlie Baquir; Yue Fu; Samuel W French; John Edwards; Brad Spellberg
Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice.
PLoS pathogens 2009;5(12):e1000703.
2009: Brad Spellberg; George H Talbot; Helen W Boucher; John S Bradley; David Gilbert; W Michael Scheld; John Edwards; John G Bartlett
Antimicrobial agents for complicated skin and skin-structure infections: justification of noninferiority margins in the absence of placebo-controlled trials.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009;49(3):383-91.
2009: Brad Spellberg; THOMAS WALSH; Dimitrios P Kontoyiannis; John Edwards; Ashraf S Ibrahim
Recent advances in the management of mucormycosis: from bench to bedside.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009;48(12):1743-51.
2009: Janos Sinkó; Bart Jan Kullberg; John Edwards; Elias Anaissie
The changing face of febrile neutropenia-from monotherapy to moulds to mucositis. Summary and comments.
The Journal of antimicrobial chemotherapy 2009;63 Suppl 1():i41-3.
2009: Peter G Pappas; Carol A Kauffman; David Andes; Daniel K Benjamin; Thierry F Calandra; John Edwards; Scott Filler; John F Fisher; Bart Jan Kullberg; Luis Ostrosky-Zeichner; Annette C Reboli; John H Rex; THOMAS WALSH; Jack D Sobel
Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009;48(5):503-35.
2009: Ashraf S Ibrahim; Teclegiorgis Gebremariam; Julie A Schwartz; John Edwards; Brad Spellberg
Posaconazole mono- or combination therapy for treatment of murine zygomycosis.
Antimicrobial agents and chemotherapy 2009;53(2):772-5.
2009: Helen W Boucher; George H Talbot; John S Bradley; John Edwards; David Gilbert; Louis B Rice; Michael Scheld; Brad Spellberg; John G Bartlett
Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2009;48(1):1-12.
2009: Ashraf S Ibrahim; John Edwards; Richard Bryant; Brad Spellberg
Economic burden of mucormycosis in the United States: can a vaccine be cost-effective?
Medical mycology : official publication of the International Society for Human and Animal Mycology 2009;47(6):592-600.
2008: Ashraf S Ibrahim; Brad Spellberg; John Edwards
Iron acquisition: a novel perspective on mucormycosis pathogenesis and treatment.
Current opinion in infectious diseases 2008;21(6):620-5.
2008: Ricardo S Almeida; Sascha Brunke; Antje Albrecht; Sascha Thewes; Michael Laue; John Edwards; Scott Filler; Bernhard Hube
the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin.
PLoS pathogens 2008;4(11):e1000217.
2008: Ashraf S Ibrahim; Teclegiorgis Gebremariam; Mingfu Liu; Georgios Chamilos; Dimitrios Kontoyiannis; Richard Mink; Kyung J Kwon-Chung; Yue Fu; Christopher D Skory; John Edwards; Brad Spellberg
Bacterial endosymbiosis is widely present among zygomycetes but does not contribute to the pathogenesis of mucormycosis.
The Journal of infectious diseases 2008;198(7):1083-90.
2008: Brad Spellberg; Ashraf S Ibrahim; Michael Yeaman; Lin Lin; Yue Fu; Valentina Avanesian; Arnold S Bayer; Scott Filler; Peter Lipke; Henry Otoo; John Edwards
The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus.
Infection and immunity 2008;76(10):4574-80.
2008: Caitlin Reed; Richard Bryant; Ashraf S Ibrahim; John Edwards; Scott Filler; Robert Goldberg; Brad Spellberg
Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;47(3):364-71.
2008: Kimberly D Gank; Michael Yeaman; Satoshi Kojima; Nannette Y Yount; Hyunsook Park; John Edwards; Scott Filler; Yue Fu
SSD1 is integral to host defense peptide resistance in Candida albicans.
Eukaryotic cell 2008;7(8):1318-27.
2008: Mindy G Schuster; John Edwards; Jack D Sobel; Rabih O Darouiche; Adolf W Karchmer; Susan Hadley; Gus Slotman; Helene Panzer; Pinaki Biswas; John H Rex
Empirical fluconazole versus placebo for intensive care unit patients: a randomized trial.
Annals of internal medicine 2008;149(2):83-90.
2008: Ben De Pauw; THOMAS WALSH; J Peter Donnelly; David A Stevens; John Edwards; Thierry Calandra; Peter G Pappas; Johan Maertens; Olivier Lortholary; Carol A Kauffman; David W Denning; Thomas Patterson; Georg Maschmeyer; Jacques Bille; William E Dismukes; Raoul Herbrecht; William W Hope; Christopher C Kibbler; Bart Jan Kullberg; Kieren Marr; Patricia Muñoz; Frank C Odds; John R Perfect; Angela Restrepo; Markus Ruhnke; Brahm H Segal; Jack D Sobel; Tania C Sorrell; Claudio Viscoli; John R Wingard; Theoklis Zaoutis; JOHN BENNETT
Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(12):1813-21.
2008: Brad Spellberg; Ashraf S Ibrahim; Lin Lin; Valentina Avanesian; Yue Fu; Peter Lipke; Henry Otoo; Tiffany Ho; John Edwards
Antibody titer threshold predicts anti-candidal vaccine efficacy even though the mechanism of protection is induction of cell-mediated immunity.
The Journal of infectious diseases 2008;197(7):967-71.
2008: Ashraf S Ibrahim; Teclegiorgis Gebremariam; Mohamed I Husseiny; David A Stevens; Yue Fu; John Edwards; Brad Spellberg
Comparison of lipid amphotericin B preparations in treating murine zygomycosis.
Antimicrobial agents and chemotherapy 2008;52(4):1573-6.
2008: Ashraf S Ibrahim; Teclegiorgis Gebremariam; Yue Fu; John Edwards; Brad Spellberg
Combination echinocandin-polyene treatment of murine mucormycosis.
Antimicrobial agents and chemotherapy 2008;52(4):1556-8.
2008: Lin Lin; Ashraf S Ibrahim; Valentina Avanesian; John Edwards; Yue Fu; Beverlie Baquir; Rebecca Taub; Brad Spellberg
Considerable differences in vaccine immunogenicities and efficacies related to the diluent used for aluminum hydroxide adjuvant.
Clinical and vaccine immunology : CVI 2008;15(3):582-4.
2008: Yue Fu; Guanpingsheng Luo; Brad J Spellberg; John Edwards; Ashraf S Ibrahim
Gene overexpression/suppression analysis of candidate virulence factors of Candida albicans.
Eukaryotic cell 2008;7(3):483-92.
2008: Brad Spellberg; Robert Guidos; David Gilbert; John Bradley; Helen W Boucher; W Michael Scheld; John G Bartlett; John Edwards
The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(2):155-64.
2007: Ashraf S Ibrahim; Teclegiorgis Gebermariam; Yue Fu; Lin Lin; Mohamed I Husseiny; Samuel W French; Julie Schwartz; Christopher D Skory; John Edwards; Brad Spellberg
The iron chelator deferasirox protects mice from mucormycosis through iron starvation.
The Journal of clinical investigation 2007;117(9):2649-57.
2007: Brad Spellberg; Loren G Miller; M N Kuo; J Bradley; W M Scheld; John Edwards
Societal costs versus savings from wild-card patent extension legislation to spur critically needed antibiotic development.
Infection 2007;35(3):167-74.
2007: Stephen A Klotz; Nand K Gaur; Richard De Armond; Donald Sheppard; Nancy Khardori; John Edwards; Peter N Lipke; Mohamed El-Azizi
Candida albicans Als proteins mediate aggregation with bacteria and yeasts.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2007;45(4):363-70.
2007: Quynh T Phan; Carter L Myers; Yue Fu; Donald C Sheppard; Michael Yeaman; William H Welch; Ashraf S Ibrahim; John Edwards; Scott Filler
Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells.
PLoS biology 2007;5(3):e64.
2007: Brad Spellberg; Mary Collins; Valentina Avanesian; Mayela Gomez; John Edwards; Christopher Cogle; David Applebaum; Yue Fu; Ashraf S Ibrahim
Optimization of a myeloid cell transfusion strategy for infected neutropenic hosts.
Journal of leukocyte biology 2007;81(3):632-41.
2007: Lisa Y Chiang; Donald C Sheppard; Vincent Bruno; Aaron P Mitchell; John Edwards; Scott Filler
Candida albicans protein kinase CK2 governs virulence during oropharyngeal candidiasis.
Cellular microbiology 2007;9(1):233-45.
2006: Caitlin Reed; Ashraf Ibrahim; John Edwards; Irwin Walot; Brad Spellberg
Deferasirox, an iron-chelating agent, as salvage therapy for rhinocerebral mucormycosis.
Antimicrobial agents and chemotherapy 2006;50(11):3968-9.
2006: Brad Spellberg; Julie Schwartz; Yue Fu; Valentina Avanesian; Jill Adler-Moore; John Edwards; Ashraf S Ibrahim
Comparison of antifungal treatments for murine fusariosis.
The Journal of antimicrobial chemotherapy 2006;58(5):973-9.
2006: Ashraf S Ibrahim; John Edwards; Yue Fu; Brad Spellberg
Deferiprone iron chelation as a novel therapy for experimental mucormycosis.
The Journal of antimicrobial chemotherapy 2006;58(5):1070-3.
2006: Gunter Rieg; Brad Spellberg; Julie Schwartz; Yue Fu; John Edwards; Donald C Sheppard; Ashraf S Ibrahim
Antifungal prophylaxis is effective against murine invasive pulmonary aspergillosis.
Antimicrobial agents and chemotherapy 2006;50(8):2895-6.
2006: Brad Spellberg; Ashraf S Ibrahim; Valentina Avanesian; Yue Fu; Carter Myers; Quynh T Phan; Scott Filler; Michael Yeaman; John Edwards
Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis.
The Journal of infectious diseases 2006;194(2):256-60.
2006: Clarissa J Nobile; David Andes; Jeniel E Nett; Frank J Smith; Fu Yue; Quynh T Phan; John Edwards; Scott Filler; Aaron P Mitchell
Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo.
PLoS pathogens 2006;2(7):e63.
2006: Ashraf S Ibrahim; Brad Spellberg; Valentina Avanesian; Yue Fu; John Edwards
The anti-Candida vaccine based on the recombinant N-terminal domain of Als1p is broadly active against disseminated candidiasis.
Infection and immunity 2006;74(5):3039-41.
2006: George H Talbot; John Bradley; John Edwards; David Gilbert; Michael Scheld; John G Bartlett
Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;42(5):657-68.
2006: Brad Spellberg; Scott Filler; John Edwards
Current treatment strategies for disseminated candidiasis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;42(2):244-51.
2005: Ashraf S Ibrahim; Beatrice B Magee; Donald C Sheppard; Molly Yang; Sarah Kauffman; Jeff Becker; John Edwards; Paul T Magee
Effects of ploidy and mating type on virulence of Candida albicans.
Infection and immunity 2005;73(11):7366-74.
2005: Brad Spellberg; Ashraf S Ibrahim; Valentina Avenissian; Scott Filler; Carter L Myers; Yue Fu; John Edwards
The anti-Candida albicans vaccine composed of the recombinant N terminus of Als1p reduces fungal burden and improves survival in both immunocompetent and immunocompromised mice.
Infection and immunity 2005;73(9):6191-3.
2005: Brad Spellberg; Mary Collins; Samuel W French; John Edwards; Yue Fu; Ashraf S Ibrahim
A phagocytic cell line markedly improves survival of infected neutropenic mice.
Journal of leukocyte biology 2005;78(2):338-44.
2005: Brad Spellberg; Ashraf S Ibrahim; John Edwards; Scott Filler
Mice with disseminated candidiasis die of progressive sepsis.
The Journal of infectious diseases 2005;192(2):336-43.
2005: Brad Spellberg; John Edwards; Ashraf Ibrahim
Novel perspectives on mucormycosis: pathophysiology, presentation, and management.
Clinical microbiology reviews 2005;18(3):556-69.
2005: Quynh T Phan; Rutilio A Fratti; Nemani V Prasadarao; John Edwards; Scott Filler
N-cadherin mediates endocytosis of Candida albicans by endothelial cells.
The Journal of biological chemistry 2005;280(11):10455-61.
2005: Kurt A Toenjes; Suzanne M Munsee; Ashraf S Ibrahim; Rachel Jeffrey; John Edwards; Douglas I Johnson
Small-molecule inhibitors of the budded-to-hyphal-form transition in the pathogenic yeast Candida albicans.
Antimicrobial agents and chemotherapy 2005;49(3):963-72.
2005: Brad Spellberg; Yue Fu; John Edwards; Ashraf S Ibrahim
Combination therapy with amphotericin B lipid complex and caspofungin acetate of disseminated zygomycosis in diabetic ketoacidotic mice.
Antimicrobial agents and chemotherapy 2005;49(2):830-2.
2005: Ashraf S Ibrahim; Joel C Bowman; Valentina Avanessian; Keturah Brown; Brad Spellberg; John Edwards; Cameron M Douglas
Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis.
Antimicrobial agents and chemotherapy 2005;49(2):721-7.
2005: Ashraf S Ibrahim; Brad Spellberg; Valentina Avenissian; Yue Fu; Scott Filler; John Edwards
Vaccination with recombinant N-terminal domain of Als1p improves survival during murine disseminated candidiasis by enhancing cell-mediated, not humoral, immunity.
Infection and immunity 2005;73(2):999-1005.
2005: Ashraf S Ibrahim; Brad Spellberg; Valentina Avanessian; Yue Fu; John Edwards
Rhizopus oryzae adheres to, is phagocytosed by, and damages endothelial cells in vitro.
Infection and immunity 2005;73(2):778-83.
2004: John H Rex; John R Wingard; Richard P Wenzel; Raoul Herbrecht; Jack D Sobel; John Edwards
The design of clinical trials that evaluate antifungal prophylaxis and combination therapy: introduction and overview.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;39 Suppl 4():S165-9.
2004: Jason M Rauceo; Nand K Gaur; Kyeng-Gea Lee; John Edwards; Stephen A Klotz; Peter N Lipke
Global cell surface conformational shift mediated by a Candida albicans adhesin.
Infection and immunity 2004;72(9):4948-55.
2004: Michael Yeaman; Darwin Cheng; Bhavesh Desai; Leon Iri Kupferwasser; Yan-Qiong Xiong; Kimberly D Gank; John Edwards; Arnold S Bayer
Susceptibility to thrombin-induced platelet microbicidal protein is associated with increased fluconazole efficacy against experimental endocarditis due to Candida albicans.
Antimicrobial agents and chemotherapy 2004;48(8):3051-6.
2004: Donald C Sheppard; Michael Yeaman; William H Welch; Quynh T Phan; Yue Fu; Ashraf S Ibrahim; Scott Filler; Mason Zhang; Alan J Waring; John Edwards
Functional and structural diversity in the Als protein family of Candida albicans.
The Journal of biological chemistry 2004;279(29):30480-9.
2004: Alysia Lea vandenBerg; Ashraf S Ibrahim; John Edwards; Kurt A Toenjes; Douglas I Johnson
Cdc42p GTPase regulates the budded-to-hyphal-form transition and expression of hypha-specific transcripts in Candida albicans.
Eukaryotic cell 2004;3(3):724-34.
2004: Yue Fu; Helen Lee; Mary Collins; Huei-Fung Tsai; Brad Spellberg; John Edwards; Kyung J Kwon-Chung; Ashraf S Ibrahim
Cloning and functional characterization of the Rhizopus oryzae high affinity iron permease (rFTR1) gene.
FEMS microbiology letters 2004;235(1):169-76.
2004: Brad Spellberg; John H Powers; Eric P Brass; Loren G Miller; John Edwards
Trends in antimicrobial drug development: implications for the future.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;38(9):1279-86.
2004: Donald C Sheppard; Gunter Rieg; Lisa Y Chiang; Scott Filler; John Edwards; Ashraf S Ibrahim
Novel inhalational murine model of invasive pulmonary aspergillosis.
Antimicrobial agents and chemotherapy 2004;48(5):1908-11.
2004: Lucio Loza; Yue Fu; Ashraf S Ibrahim; Donald C Sheppard; Scott Filler; John Edwards
Functional analysis of the Candida albicans ALS1 gene product.
Yeast (Chichester, England) 2004;21(6):473-82.
2004: Donald C Sheppard; John Edwards
Development of a vaccine for invasive aspergillosis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;38(8):1137-8.
2004: Peter G Pappas; John H Rex; Jack D Sobel; Scott Filler; William E Dismukes; THOMAS WALSH; John Edwards
Guidelines for treatment of candidiasis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2004;38(2):161-89.
2004: Angela A Sanchez; Douglas A Johnston; Carter Myers; John Edwards; Aaron P Mitchell; Scott Filler
Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro.
Infection and immunity 2004;72(1):598-601.
2003: Ashraf S Ibrahim; Valentina Avanessian; Brad Spellberg; John Edwards
Liposomal amphotericin B, and not amphotericin B deoxycholate, improves survival of diabetic mice infected with Rhizopus oryzae.
Antimicrobial agents and chemotherapy 2003;47(10):3343-4.
2003: Brad Spellberg; Douglas Johnston; Quynh T Phan; John Edwards; Samuel W French; Ashraf S Ibrahim; Scott Filler
Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis.
Infection and immunity 2003;71(10):5756-64.
2003: Peter G Pappas; John H Rex; Jeannette Lee; Richard J Hamill; Robert A Larsen; William G Powderly; Carol A Kauffman; Newton Hyslop; Julie E Mangino; Stanley Chapman; Harold W Horowitz; John Edwards; William E Dismukes
A prospective observational study of candidemia: epidemiology, therapy, and influences on mortality in hospitalized adult and pediatric patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;37(5):634-43.
2003: John H Rex; Peter G Pappas; Adolf W Karchmer; Jack D Sobel; John Edwards; Susan Hadley; Corstiaan Brass; Jose A Vazquez; Stanley W Chapman; Harold W Horowitz; Marcus Zervos; David McKinsey; Jeannette Lee; Timothy Babinchak; Robert W Bradsher; John D Cleary; David M Cohen; Larry H Danziger; Mitchell Goldman; Jesse Goodman; Eileen Hilton; Newton E Hyslop; Daniel H Kett; Jon Lutz; Robert Rubin; W Michael Scheld; Mindy Schuster; Bryan Simmons; David Stein; Ronald G Washburn; Linda Mautner; Teng-Chiao Chu; Helene Panzer; Rebecca B Rosenstein; Jenia Booth
A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(10):1221-8.
2003: Brad Spellberg; Gunter Rieg; Arnold Bayer; John Edwards
Lack of cross-hepatotoxicity between fluconazole and voriconazole.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(8):1091-3.
2002: David N Gilbert; John Edwards
Is there hope for the prevention of future antimicrobial shortages?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002;35(2):215-6; author reply 216-7.
2002: Yue Fu; Ashraf S Ibrahim; Donald C Sheppard; Yee-Chun Chen; Samuel W French; Jim E Cutler; Scott Filler; John Edwards
Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway.
Molecular microbiology 2002;44(1):61-72.
2002: S Ascioglu; John H Rex; Ben E de Pauw; JOHN BENNETT; J Bille; F Crokaert; David W Denning; J Peter Donnelly; John Edwards; Z Erjavec; D Fiere; Olivier Lortholary; Johan Maertens; Jacques Meis; Thomas Patterson; J Ritter; Dominik Selleslag; P M Shah; D A Stevens; THOMAS WALSH
Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002;34(1):7-14.
2001: Lisa Saiman; E Ludington; J D Dawson; Jan Patterson; S Rangel-Frausto; RT Wiblin; Henry M Blumberg; Michael A Pfaller; M Rinaldi; John Edwards; Richard P Wenzel; William R Jarvis
Risk factors for Candida species colonization of neonatal intensive care unit patients.
The Pediatric infectious disease journal 2001;20(12):1119-24.
2001: Henry M Blumberg; William R Jarvis; J Michael Soucie; John Edwards; Jan Patterson; Michael A Pfaller; MS Rangel-Frausto; Michael G Rinaldi; Lisa Saiman; RT Wiblin; Richard P Wenzel
Risk factors for candidal bloodstream infections in surgical intensive care unit patients: the NEMIS prospective multicenter study. The National Epidemiology of Mycosis Survey.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;33(2):177-86.
2001: L G Miller; R A Hajjeh; John Edwards
Estimating the cost of nosocomial candidemia in the united states.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32(7):1110.
2001: John H Rex; THOMAS WALSH; Jack D Sobel; Scott Filler; Peter G Pappas; William E Dismukes; John Edwards
Reply to Dr. Chandrasekar (Clin Infect Dis 2001; 32:320-1) and Drs. Marr and Boeckh (Clin Infect Dis 2001; 32:321).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32(3):518-9.
2001: John Edwards
Management of severe candidal infections: integration and review of current guidelines for treatment and prevention.
Current clinical topics in infectious diseases 2001;21():135-47.
2001: B Spellberg; John Edwards
Type 1/Type 2 immunity in infectious diseases.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2001;32(1):76-102.
2000: D Davis; John Edwards; Aaron P Mitchell; A S Ibrahim
Candida albicans RIM101 pH response pathway is required for host-pathogen interactions.
Infection and immunity 2000;68(10):5953-9.
2000: Lisa Saiman; E Ludington; Michael A Pfaller; S Rangel-Frausto; RT Wiblin; J Dawson; Henry M Blumberg; Jan Patterson; M Rinaldi; John Edwards; Richard P Wenzel; William R Jarvis
Risk factors for candidemia in Neonatal Intensive Care Unit patients. The National Epidemiology of Mycosis Survey study group.
The Pediatric infectious disease journal 2000;19(4):319-24.
2000: John H Rex; THOMAS WALSH; Jack D Sobel; Scott Filler; Peter G Pappas; William E Dismukes; John Edwards
Practice guidelines for the treatment of candidiasis. Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;30(4):662-78.
2000: N Tsuchimori; Laura L Sharkey; William A Fonzi; S W French; John Edwards; Scott Filler
Reduced virulence of HWP1-deficient mutants of Candida albicans and their interactions with host cells.
Infection and immunity 2000;68(4):1997-2002.
2000: Karl V Clemons; Vera Calich; Eva Burger; Scott Filler; Monica Grazziutti; J Murphy; Emmanuel Roilides; Ana Campa; M R Dias; John Edwards; Y Fu; G Fernandes-Bordignon; A Ibrahim; H Katsifa; Cristina Gil Lamaignere; LH Meloni-Bruneri; John H Rex; Cherylyn A Savary; CF Xidieh
Pathogenesis I: interactions of host cells and fungi.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2000;38 Suppl 1():99-111.
1999: F Marco; Shawn R Lockhart; Michael A Pfaller; Claude Pujol; MS Rangel-Frausto; T Wiblin; Henry M Blumberg; John Edwards; William R Jarvis; Lisa Saiman; Jan Patterson; Michael G Rinaldi; Richard P Wenzel; David Soll
Elucidating the origins of nosocomial infections with Candida albicans by DNA fingerprinting with the complex probe Ca3.
Journal of clinical microbiology 1999;37(9):2817-28.
1999: MS Rangel-Frausto; T Wiblin; Henry M Blumberg; Lisa Saiman; Jan Patterson; M Rinaldi; Michael A Pfaller; John Edwards; William R Jarvis; J Dawson; Richard P Wenzel
National epidemiology of mycoses survey (NEMIS): variations in rates of bloodstream infections due to Candida species in seven surgical intensive care units and six neonatal intensive care units.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1999;29(2):253-8.
1999: Gunter Rieg; Yue Fu; Ashraf S Ibrahim; X Zhou; Scott Filler; John Edwards
Unanticipated heterogeneity in growth rate and virulence among Candida albicans AAF1 null mutants.
Infection and immunity 1999;67(7):3193-8.
1998: John Edwards; K E Edwards
Reflections on studies in developing countries.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1998;26(6):1367.
1998: Ashraf S Ibrahim; Scott Filler; Dominique Sanglard; John Edwards; B Hube
Secreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells.
Infection and immunity 1998;66(6):3003-5.
1998: Michael A Pfaller; Shawn A Messer; AK Houston; MS Rangel-Frausto; T Wiblin; Henry M Blumberg; John Edwards; William R Jarvis; Michael Martin; H C Neu; Lisa Saiman; Jan Patterson; J C Dibb; C M Roldan; Michael G Rinaldi; Richard P Wenzel
National epidemiology of mycoses survey: a multicenter study of strain variation and antifungal susceptibility among isolates of Candida species.
Diagnostic microbiology and infectious disease 1998;31(1):289-96.
1998: Yue Fu; Scott Filler; Brad Spellberg; William A Fonzi; Ashraf S Ibrahim; T Kanbe; Mahmoud A Ghannoum; John Edwards
Cloning and characterization of CAD1/AAF1, a gene from Candida albicans that induces adherence to endothelial cells after expression in Saccharomyces cerevisiae.
Infection and immunity 1998;66(5):2078-84.
1998: Yue Fu; Gunter Rieg; William A Fonzi; Paul H Belanger; John Edwards; Scott Filler
Expression of the Candida albicans gene ALS1 in Saccharomyces cerevisiae induces adherence to endothelial and epithelial cells.
Infection and immunity 1998;66(4):1783-6.
1998: Rutilio A Fratti; Paul H Belanger; Mahmoud A Ghannoum; John Edwards; Scott Filler
Endothelial cell injury caused by Candida albicans is dependent on iron.
Infection and immunity 1998;66(1):191-6.
1997: WALTER HUGHES; D Armstrong; Gerald P Bodey; Arthur E Brown; John Edwards; Ronald Feld; Philip A Pizzo; Kenneth V I Rolston; Jerry L Shenep; L S Young
1997 guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;25(3):551-73.
1997: John Edwards; Gerald P Bodey; R A Bowden; T Büchner; Ben E de Pauw; Scott Filler; M A Ghannoum; M Glauser; Raoul Herbrecht; Carol A Kauffman; S Kohno; P Martino; F Meunier; T Mori; Michael A Pfaller; J H Rex; T R Rogers; Robert Rubin; J Solomkin; Claudio Viscoli; THOMAS WALSH; M White
International Conference for the Development of a Consensus on the Management and Prevention of Severe Candidal Infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;25(1):43-59.
1996: Rutilio A Fratti; M A Ghannoum; John Edwards; Scott Filler
Gamma interferon protects endothelial cells from damage by Candida albicans by inhibiting endothelial cell phagocytosis.
Infection and immunity 1996;64(11):4714-8.
1996: Scott Filler; A S Pfunder; B J Spellberg; J P Spellberg; John Edwards
Candida albicans stimulates cytokine production and leukocyte adhesion molecule expression by endothelial cells.
Infection and immunity 1996;64(7):2609-17.
1996: Michael Yeaman; S S Soldan; M A Ghannoum; John Edwards; Scott Filler; Arnold S Bayer
Resistance to platelet microbicidal protein results in increased severity of experimental Candida albicans endocarditis.
Infection and immunity 1996;64(4):1379-84.
1996: M D Witt; R J Lewis; Robert A Larsen; E N Milefchik; M A Leal; R H Haubrich; J A Richie; John Edwards; M A Ghannoum
Identification of patients with acute AIDS-associated cryptococcal meningitis who can be effectively treated with fluconazole: the role of antifungal susceptibility testing.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1996;22(2):322-8.
1995: M A Ghannoum; Y Fu; Ashraf S Ibrahim; L A Mortara; M C Shafiq; John Edwards; R S Criddle
In vitro determination of optimal antifungal combinations against Cryptococcus neoformans and Candida albicans.
Antimicrobial agents and chemotherapy 1995;39(11):2459-65.
1995: Ashraf S Ibrahim; Scott Filler; M S Alcouloumre; T R Kozel; John Edwards; M A Ghannoum
Adherence to and damage of endothelial cells by Cryptococcus neoformans in vitro: role of the capsule.
Infection and immunity 1995;63(11):4368-74.
1995: John H Rex; JOHN BENNETT; A M Sugar; P G Pappas; Jonathan S Serody; John Edwards; R G Washburn
Intravascular catheter exchange and duration of candidemia. NIAID Mycoses Study Group and the Candidemia Study Group.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;21(4):994-6.
1995: Brian Currie; H Sanati; Ashraf S Ibrahim; John Edwards; Arturo Casadevall; M A Ghannoum
Sterol compositions and susceptibilities to amphotericin B of environmental Cryptococcus neoformans isolates are changed by murine passage.
Antimicrobial agents and chemotherapy 1995;39(9):1934-7.
1995: Ashraf S Ibrahim; F Mirbod; Scott Filler; Yoshiko Banno; Garry T Cole; Yasuo Kitajima; John Edwards; Yoshinori Nozawa; M A Ghannoum
Evidence implicating phospholipase as a virulence factor of Candida albicans.
Infection and immunity 1995;63(5):1993-8.
1995: A B Radner; M D Witt; John Edwards
Acute invasive rhinocerebral zygomycosis in an otherwise healthy patient: case report and review.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995;20(1):163-6.
1995: Scott Filler; John Edwards
When and how to treat serious candidal infections: concepts and controversies.
Current clinical topics in infectious diseases 1995;15():1-18.
1994: John H Rex; JOHN BENNETT; A M Sugar; P G Pappas; Charles van der Horst; John Edwards; R G Washburn; W M Scheld; A W Karchmer; A P Dine
A randomized trial comparing fluconazole with amphotericin B for the treatment of candidemia in patients without neutropenia. Candidemia Study Group and the National Institute.
The New England journal of medicine 1994;331(20):1325-30.
1994: M A Ghannoum; B J Spellberg; Ashraf S Ibrahim; J A Ritchie; Brian Currie; E D Spitzer; John Edwards; Arturo Casadevall
Sterol composition of Cryptococcus neoformans in the presence and absence of fluconazole.
Antimicrobial agents and chemotherapy 1994;38(9):2029-33.
1994: Michael Yeaman; Paul M Sullam; Paul Dazin; M A Ghannoum; John Edwards; Arnold S Bayer
Fluconazole and platelet microbicidal protein inhibit Candida adherence to platelets in vitro.
Antimicrobial agents and chemotherapy 1994;38(7):1460-5.
1994: Scott Filler; Basil O Ibe; Ashraf S Ibrahim; M A Ghannoum; J Usha Raj; John Edwards
Mechanisms by which Candida albicans induces endothelial cell prostaglandin synthesis.
Infection and immunity 1994;62(3):1064-9.
1994: Richard Calderone; R Diamond; J M Senet; J Warmington; S Filler; John Edwards
Host cell-fungal cell interactions.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology 1994;32 Suppl 1():151-68.
1993: M S Alcouloumre; M A Ghannoum; Ashraf S Ibrahim; Michael Selsted; John Edwards
Fungicidal properties of defensin NP-1 and activity against Cryptococcus neoformans in vitro.
Antimicrobial agents and chemotherapy 1993;37(12):2628-32.
1993: J N Swerdloff; Scott Filler; John Edwards
Severe candidal infections in neutropenic patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1993;17 Suppl 2():S457-67.
1993: Ashraf S Ibrahim; Scott Filler; M A Ghannoum; John Edwards
Interferon-gamma protects endothelial cells from damage by Candida albicans.
The Journal of infectious diseases 1993;167(6):1467-70.
1993: Michael Yeaman; Ashraf S Ibrahim; John Edwards; A S Bayer; M A Ghannoum
Thrombin-induced rabbit platelet microbicidal protein is fungicidal in vitro.
Antimicrobial agents and chemotherapy 1993;37(3):546-53.
1992: M A Ghannoum; Ashraf S Ibrahim; Y Fu; M C Shafiq; John Edwards; R S Criddle
Susceptibility testing of Cryptococcus neoformans: a microdilution technique.
Journal of clinical microbiology 1992;30(11):2881-6.
1992: M A Ghannoum; Scott Filler; Ashraf S Ibrahim; Y Fu; John Edwards
Modulation of interactions of Candida albicans and endothelial cells by fluconazole and amphotericin B.
Antimicrobial agents and chemotherapy 1992;36(10):2239-44.
1992: John Edwards
Should all patients with candidemia be treated with antifungal agents?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1992;15(3):422-3.
1992: John Edwards; C L Mayer; Scott Filler; E Wadsworth; Richard Calderone
Cell extracts of Candida albicans block adherence of the organisms to endothelial cells.
Infection and immunity 1992;60(8):3087-91.
1992: C L Mayer; Scott Filler; John Edwards
Candida albicans adherence to endothelial cells.
Microvascular research 1992;43(2):218-26.
1992: John Edwards; Scott Filler
Current strategies for treating invasive candidiasis: emphasis on infections in nonneutropenic patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1992;14 Suppl 1():S106-13.
1992: M D Witt; John Edwards
Pancreatic abscess and infected pancreatic pseudocyst: diagnosis and treatment.
Current clinical topics in infectious diseases 1992;12():111-37.
1991: Scott Filler; Basil O Ibe; P M Luckett; J Usha Raj; John Edwards
Candida albicans stimulates endothelial cell eicosanoid production.
The Journal of infectious diseases 1991;164(5):928-35.
1991: John Edwards
Invasive candida infections--evolution of a fungal pathogen.
The New England journal of medicine 1991;324(15):1060-2.
1991: Scott Filler; M A Crislip; C L Mayer; John Edwards
Comparison of fluconazole and amphotericin B for treatment of disseminated candidiasis and endophthalmitis in rabbits.
Antimicrobial agents and chemotherapy 1991;35(2):288-92.
1990: D G Fish; Neil M Ampel; John N Galgiani; C L Dols; P C Kelly; C H Johnson; Demosthenes Pappagianis; John Edwards; R B Wasserman; R J Clark
Coccidioidomycosis during human immunodeficiency virus infection. A review of 77 patients.
Medicine 1990;69(6):384-91.
1990: C L Mayer; R D Diamond; John Edwards
Recognition of binding sites on Candida albicans by monoclonal antibodies to human leukocyte antigens.
Infection and immunity 1990;58(11):3765-9.
1989: M A Crislip; John Edwards
Candidiasis.
Infectious disease clinics of North America 1989;3(1):103-33.
1988: John Edwards
Systemic symptoms from Candida in the gut: real or imaginary?
Bulletin of the New York Academy of Medicine 1988;64(6):544-9.
1987: M Crandall; John Edwards
Segregation of proteinase-negative mutants from heterozygous Candida albicans.
Journal of general microbiology 1987;133(10):2817-24.
1987: Scott Filler; L C Der; C L Mayer; P D Christenson; John Edwards
An enzyme-linked immunosorbent assay for quantifying adherence of Candida to human vascular endothelium.
The Journal of infectious diseases 1987;156(4):561-6.
1987: John Edwards; Daniel Rotrosen; J W Fontaine; Christian C Haudenschild; R D Diamond
Neutrophil-mediated protection of cultured human vascular endothelial cells from damage by growing Candida albicans hyphae.
Blood 1987;69(5):1450-7.
1986: John Edwards; T A Gaither; John O'Shea; Daniel Rotrosen; T J Lawley; S A Wright; M M Frank; I Green
Expression of specific binding sites on Candida with functional and antigenic characteristics of human complement receptors.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(11):3577-83.
1986: Daniel Rotrosen; R A Calderone; John Edwards
Adherence of Candida species to host tissues and plastic surfaces.
Reviews of infectious diseases 1986;8(1):73-85.
1985: Daniel Rotrosen; John Edwards; T R Gibson; J C Moore; A H Cohen; I Green
Adherence of Candida to cultured vascular endothelial cells: mechanisms of attachment and endothelial cell penetration.
The Journal of infectious diseases 1985;152(6):1264-74.
1985: M R Greenberg; S M Lippman; V S Grinnell; M F Colman; John Edwards
Computed tomographic findings in orbital Mucor.
The Western journal of medicine 1985;143(1):102-3.
1983: Daniel Rotrosen; T R Gibson; John Edwards
Adherence of candida species to intravenous catheters.
The Journal of infectious diseases 1983;147(3):594.
1982: L J Hockey; N K Fujita; T R Gibson; Daniel Rotrosen; J Z Montgomerie; John Edwards
Detection of fungemia obscured by concomitant bacteremia: in vitro and in vivo studies.
Journal of clinical microbiology 1982;16(6):1080-5.
1982: N K Fujita; D K Henderson; L J Hockey; L B Guze; John Edwards
Comparative ocular pathogenicity of Cryptococcus neoformans, Candida glabrata, and Aspergillus fumigatus in the rabbit.
Investigative ophthalmology & visual science 1982;22(3):410-4.
1981: D K Henderson; John Edwards; J Z Montgomerie
Hematogenous candida endophthalmitis in patients receiving parenteral hyperalimentation fluids.
The Journal of infectious diseases 1981;143(5):655-61.
1981: N K Fujita; M Reynard; F L Sapico; L B Guze; John Edwards
Cryptococcal intracerebral mass lesions: the role of computed tomography and nonsurgical management.
Annals of internal medicine 1981;94(3):382-8.
1981: A S Bayer; John Edwards; L B Guze
Experimental intraabdominal candidiasis in rabbits: therapy with low-total-dose intravenous amphotericin B.
Antimicrobial agents and chemotherapy 1981;19(1):179-84.
1981: N K Fujita; John Edwards
Combined in vitro effect of amphotericin B and rifampin on Cryptococcus neoformans.
Antimicrobial agents and chemotherapy 1981;19(1):196-8.
1980: John Edwards; J Morrison; D K Henderson; J Z Montgomerie
Combined effect of amphotericin B and rifampin on Candida species.
Antimicrobial agents and chemotherapy 1980;17(3):484-7.
1980: N Fujita; V Grinnell; John Edwards; R A Feldman
Management of central nervous system cryptococcosis.
The Western journal of medicine 1980;132(2):123-33.
1980: D K Henderson; L J Hockey; L J Vukalcic; John Edwards
Effect of immunosuppression on the development of experimental hematogenous Candida endophthalmitis.
Infection and immunity 1980;27(2):628-31.
1980: A S Bayer; John Edwards; L B Guze
Experimental intraabdominal candidiasis: macroscopic, microscopic and cultural natural history.
Digestion 1980;20(6):365-74.
1979: D K Henderson; John Edwards; K Ishida; L B Guze
Experimental hematogenous Candida endophthalmitis: diagnostic approaches.
Infection and immunity 1979;23(3):858-62.
1978: John Edwards; R I Lehrer; E R Stiehm; T J Fischer; L S Young
Severe candidal infections: clinical perspective, immune defense mechanisms, and current concepts of therapy.
Annals of internal medicine 1978;89(1):91-106.
1978: J Z Montgomerie; John Edwards
Association of infection due to Candida albicans with intravenous hyperalimentation.
The Journal of infectious diseases 1978;137(2):197-201.
1977: M Cohen; John Edwards; T J Hensley; L B Guze
Experimental hematogenous Candida albicans endophthalmitis: electron microscopy.
Investigative ophthalmology & visual science 1977;16(6):498-511.
1977: I Nilsson-Ehle; T T Yoshikawa; John Edwards; M C Schotz; L B Guze
Quantitation of amphotericin B with use of high-pressure liquid chromatography.
The Journal of infectious diseases 1977;135(3):414-22.
1977: P A Oill; J Z Montgomerie; W S Cryan; John Edwards
Specialty conference. Infectious disease emergencies. Part V: patients presenting with localized infections.
The Western journal of medicine 1977;126(3):196-208.
1977: John Edwards; J Z Montgomerie; K Ishida; J O Morrison; L B Guze
Experimental hematogenous endophthalmitis due to Candida: species variation in ocular pathogenicity.
The Journal of infectious diseases 1977;135(2):294-7.
1976: A S Bayer; John Edwards; J S Seidel; L B Guze
Candida meningitis. Report of seven cases and review of the english literature.
Medicine 1976;55(6):477-86.
1975: John Edwards; S B Turkel; H A Elder; R W Rand; L B Guze
Hematogenous candida osteomyelitis. Report of three cases and review of the literature.
The American journal of medicine 1975;59(1):89-94.
1975: J Z Montgomerie; John Edwards; L B Guze
Synergism of amphotericin B and 5-fluorocytosine for candida species.
The Journal of infectious diseases 1975;132(1):82-6.
1975: John Edwards; J Z Montgomerie; R Y Foos; V K Shaw; L B Guze
Experimental hematogenous endophthalmitis caused by Candida albicans.
The Journal of infectious diseases 1975;131(6):649-57.
1975: J Madison; K Wang; F L Gobel; John Edwards
Prosthetic aortic valvular endocarditis.
Circulation 1975;51(5):940-9.
1975: R Thell; F H Martin; John Edwards
Bacterial endocarditis in subjects 60 years of age and older.
Circulation 1975;51(1):174-82.
1974: John Edwards; R Y Foos; J Z Montgomerie; L B Guze
Ocular manifestations of Candida septicemia: review of seventy-six cases of hematogenous Candida endophthalmitis.
Medicine 1974;53(1):47-75.
1972: A E Becker; M J Becker; F H Martin; John Edwards
Bland thrombosis and infection in relation to intracardiac catheter.
Circulation 1972;46(1):200-3.