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Angus Nairn

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TOP 3
Barbara Dancheck; Michael J Ragusa; Marc Allaire; Angus Nairn; Rebecca Page; Wolfgang Peti
Molecular investigations of the structure and function of the protein phosphatase 1-spinophilin-inhibitor 2 heterotrimeric complex.
Michael J Ragusa; Marc Allaire; Angus Nairn; Rebecca Page; Wolfgang Peti
Flexibility in the PP1:spinophilin holoenzyme.
Yongfang Zhang; Pradeep Kurup; Jian Xu; Nikisha Carty; Stephanie M Fernandez; Haakon B Nygaard; Christopher Pittenger; Paul Greengard; Stephen M Strittmatter; Angus Nairn; Paul J Lombroso
Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model.

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All Publications

2011: Barbara Dancheck; Michael J Ragusa; Marc Allaire; Angus Nairn; Rebecca Page; Wolfgang Peti
Molecular investigations of the structure and function of the protein phosphatase 1-spinophilin-inhibitor 2 heterotrimeric complex.
Biochemistry 2011;50(7):1238-46.
2011: Michael J Ragusa; Marc Allaire; Angus Nairn; Rebecca Page; Wolfgang Peti
Flexibility in the PP1:spinophilin holoenzyme.
FEBS letters 2011;585(1):36-40.
2010: Yongfang Zhang; Pradeep Kurup; Jian Xu; Nikisha Carty; Stephanie M Fernandez; Haakon B Nygaard; Christopher Pittenger; Paul Greengard; Stephen M Strittmatter; Angus Nairn; Paul J Lombroso
Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(44):19014-9.
2010: Thomas McAvoy; Angus Nairn
Serine/threonine protein phosphatase assays.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2010;Chapter 18():Unit18.18.
2010: Carmen E Flores; Roger Cachope; Srikant Nannapaneni; Smaranda Ene; Angus Nairn; Alberto E Pereda
Variability of distribution of Ca(2+)/calmodulin-dependent kinase II at mixed synapses on the mauthner cell: colocalization and association with connexin 35.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(28):9488-99.
2010: Ilaria Ceglia; Yong Kim; Angus Nairn; Paul Greengard
Signaling pathways controlling the phosphorylation state of WAVE1, a regulator of actin polymerization.
Journal of neurochemistry 2010;114(1):182-90.
2010: Cecilia Conde; Cristina Arias; Maria Robin; Aiqun Li; Masaki Saito; Jen-Zen Chuang; Angus Nairn; Ching-Hwa Sung; Alfredo Cáceres
Evidence for the involvement of Lfc and Tctex-1 in axon formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(19):6793-800.
2010: J R Glausier; M Maddox; H C Hemmings; Angus Nairn; Paul Greengard; E Chris Muly
Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex.
Neuroscience 2010;167(2):428-38.
2010: Pradeep Kurup; Yongfang Zhang; Jian Xu; Deepa V Venkitaramani; Vahram Haroutunian; Paul Greengard; Angus Nairn; Paul J Lombroso
Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(17):5948-57.
2010: Kimberly L Dodge-Kafka; Andrea Bauman; Nicole Mayer; Edward Henson; Lorena Heredia; Jung Ahn; Thomas McAvoy; Angus Nairn; Michael Kapiloff
cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3.
The Journal of biological chemistry 2010;285(15):11078-86.
2010: Michael J Ragusa; Barbara Dancheck; David A Critton; Angus Nairn; Rebecca Page; Wolfgang Peti
Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nature structural & molecular biology 2010;17(4):459-64.
2010: Mingming Zhou; Heike Rebholz; Christine Brocia; Jennifer Schmidt; Allen Fienberg; Angus Nairn; Paul Greengard; Marc Flajolet
Forebrain overexpression of CK1delta leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4401-6.
2010: Darren Goffin; Afia B Ali; Nazir Rampersaud; Alexander Harkavyi; Celine Fuchs; Peter S Whitton; Angus Nairn; Jasmina N Jovanovic
Dopamine-dependent tuning of striatal inhibitory synaptogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(8):2935-50.
2009: Dilja D Krueger; Jessica L Howell; Heyman Oo; Peter Olausson; Jane R Taylor; Angus Nairn
Prior chronic cocaine exposure in mice induces persistent alterations in cognitive function.
Behavioural pharmacology 2009;20(8):695-704.
2009: Heather Davidson; Abigail Wilson; Robert D Gray; Alex Horsley; Ian A Pringle; Gerry McLachlan; Angus Nairn; Cordelia Stearns; James Gibson; Emma Holder; Lisa Jones; Ann Doherty; Rebecca Coles; Stephanie G Sumner-Jones; Marguerite Wasowicz; Michelle Manvell; Uta Griesenbach; Stephen C Hyde; Deborah R Gill; Jane Davies; D David S Collie; Eric W F W Alton; David J Porteous; A Christopher Boyd
An immunocytochemical assay to detect human CFTR expression following gene transfer.
Molecular and cellular probes 2009;23(6):272-80.
2009: Christian Hansen; Jill Howlin; Anders Tengholm; Oleg Dyachok; Wolfgang F Vogel; Angus Nairn; Paul Greengard; Tommy Andersson
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
The Journal of biological chemistry 2009;284(40):27533-43.
2009: Heike Rebholz; Akinori Nishi; Sabine Liebscher; Angus Nairn; Marc Flajolet; Paul Greengard
CK2 negatively regulates Galphas signaling.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(33):14096-101.
2009: Judy Qiju Wu; Jessie Yanxiang Guo; Wanli Tang; Chih-Sheng Yang; Christopher Freel; Chen Chen; Angus Nairn; Sally Kornbluth
PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation.
Nature cell biology 2009;11(5):644-51.
2009: Megumi Sakuma; Emi Tanaka; Hidenori Taru; Susumu Tomita; Sam Gandy; Angus Nairn; Tadashi Nakaya; Tohru Yamamoto; Toshiharu Suzuki
Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.
Journal of neurochemistry 2009;109(2):465-75.
2009: Thomas McAvoy; Ming-ming Zhou; Paul Greengard; Angus Nairn
Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3531-6.
2009: Shogo Endo; Fumihiro Shutoh; TUNG LE; Takehito Okamoto; Toshio Ikeda; Michiyuki Suzuki; Shigenori Kawahara; Dai Yanagihara; Yamato Sato; Kazuyuki Yamada; Toshiro Sakamoto; Yutaka Kirino; Nicholas A Hartell; Kazuhiko Yamaguchi; Shigeyoshi Itohara; Angus Nairn; Paul Greengard; Soichi Nagao; Masao Ito
Dual involvement of G-substrate in motor learning revealed by gene deletion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3525-30.
2009: Yong Kim; Merilee A Teylan; Matthew Baron; Adam Sands; Angus Nairn; Paul Greengard
Methylphenidate-induced dendritic spine formation and DeltaFosB expression in nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2915-20.
2009: Lina Cheng; Stephen H Pilder; Angus Nairn; Shandilya Ramdas; Srinivasan Vijayaraghavan
PP1gamma2 and PPP1R11 are parts of a multimeric complex in developing testicular germ cells in which their steady state levels are reciprocally related.
PloS one 2009;4(3):e4861.
2009: Rungnapa Hirunsatit; Elizabeth D George; Barbara K Lipska; Hani M Elwafi; Lisa Sander; Carolyn M Yrigollen; Joel Gelernter; Elena L Grigorenko; Jaakko Lappalainen; Shrikant M Mane; Angus Nairn; Joel E Kleinman; Arthur A Simen
Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activity.
Pharmacogenetics and genomics 2009;19(1):53-65.
2008: Marc Flajolet; Zhongfeng Wang; Marie Futter; Weixing Shen; Nina Nuangchamnong; Jacob Bendor; Iwona Wallach; Angus Nairn; Dalton Surmeier; Paul Greengard
FGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticity.
Nature neuroscience 2008;11(12):1402-9.
2008: Douglas A Meyer; Edmond Richer; Stanley A Benkovic; Kanehiro Hayashi; Janice W Kansy; Carly F Hale; Lily Y Moy; Yong Kim; James P O'Callaghan; Li-Huei Tsai; Paul Greengard; Angus Nairn; Christopher William Cowan; Diane B Miller; Peter P Antich; James A Bibb
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18561-6.
2008: Barbara Dancheck; Angus Nairn; Wolfgang Peti
Detailed structural characterization of unbound protein phosphatase 1 inhibitors.
Biochemistry 2008;47(47):12346-56.
2008: Suprabha Pulipparacharuvil; William Renthal; Carly F Hale; Makoto Taniguchi; Guanghua Xiao; Arvind Kumar; Scott J Russo; Devanjan Sikder; Colleen M Dewey; Maya M Davis; Paul Greengard; Angus Nairn; Eric J Nestler; Christopher William Cowan
Cocaine regulates MEF2 to control synaptic and behavioral plasticity.
Neuron 2008;59(4):621-33.
2008: Xiao-Jian Han; Yun-Fei Lu; Shun-Ai Li; Taku Kaitsuka; Yasufumi Sato; Kazuhito Tomizawa; Angus Nairn; Kohji Takei; Hideki Matsui; Masayuki Matsushita
CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology.
The Journal of cell biology 2008;182(3):573-85.
2008: Maxfield P Flynn; Evelyn T Maizels; Amelia B Karlsson; Thomas McAvoy; Jung-Hyuck Ahn; Angus Nairn; Mary Hunzicker-Dunn
Luteinizing hormone receptor activation in ovarian granulosa cells promotes protein kinase A-dependent dephosphorylation of microtubule-associated protein 2D.
Molecular endocrinology (Baltimore, Md.) 2008;22(7):1695-710.
2008: E Chris Muly; Angus Nairn; Paul Greengard; Don Rainnie
Subcellular distribution of the Rho-GEF Lfc in primate prefrontal cortex: effect of neuronal activation.
The Journal of comparative neurology 2008;508(6):927-39.
2008: Alexandre Stipanovich; Emmanuel Valjent; Miriam Matamales; Akinori Nishi; Jung-Hyuck Ahn; Matthieu Maroteaux; Jesus Bertran-Gonzalez; Karen Brami-Cherrier; hervé enslen; Anne-Gaëlle Corbillé; Odile Filhol; Angus Nairn; Paul Greengard; Denis Hervé; Jean-Antoine Girault
A phosphatase cascade by which rewarding stimuli control nucleosomal response.
Nature 2008;453(7197):879-84.
2008: Jee Young Sung; Olivia Engmann; Merilee A Teylan; Angus Nairn; Paul Greengard; Yong Kim
WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):3112-6.
2007: Paolo Emilio Barbano; Marina Spivak; Marc Flajolet; Angus Nairn; Paul Greengard; Leslie Greengard
A mathematical tool for exploring the dynamics of biological networks.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19169-74.
2007: Dilja D Krueger; Angus Nairn
Expression of PKC substrate proteins, GAP-43 and neurogranin, is downregulated by cAMP signaling and alterations in synaptic activity.
The European journal of neuroscience 2007;26(11):3043-53.
2007: Peter Olausson; J David Jentsch; Dilja D Krueger; Natalie C Tronson; Angus Nairn; Jane R Taylor
Orbitofrontal cortex and cognitive-motivational impairments in psychostimulant addiction: evidence from experiments in the non-human primate.
Annals of the New York Academy of Sciences 2007;1121():610-38.
2007: Tohru Kimura; Patrick B Allen; Angus Nairn; Michael J Caplan
Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase.
Molecular biology of the cell 2007;18(11):4508-18.
2007: Tingting Ju; Michael J Ragusa; Jebecka Hudak; Angus Nairn; Wolfgang Peti
Structural characterization of the neurabin sterile alpha motif domain.
Proteins 2007;69(1):192-8.
2007: Giovanni Piccoli; Chiara Verpelli; Noemi Tonna; Stefano Romorini; Massimo Alessio; Angus Nairn; Angela Bachi; Carlo Sala
Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons.
Journal of proteome research 2007;6(8):3203-15.
2007: Jung-Hyuck Ahn; Jee Young Sung; Thomas McAvoy; Akinori Nishi; Veerle Janssens; Jozef Goris; Paul Greengard; Angus Nairn
The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9876-81.
2007: Erika C Andrade; Dilja D Krueger; Angus Nairn
Recent advances in neuroproteomics.
Current opinion in molecular therapeutics 2007;9(3):270-81.
2007: Hideo Matsuzaki; Yoshio Minabe; Kazuhiko Nakamura; Katsuaki Suzuki; Yasuhide Iwata; Yoshimoto Sekine; Kenji J Tsuchiya; Genichi Sugihara; Shiro Suda; Nori Takei; Daiichiro Nakahara; Kenji Hashimoto; Angus Nairn; Norio Mori; Kohji Sato
Disruption of reelin signaling attenuates methamphetamine-induced hyperlocomotion.
The European journal of neuroscience 2007;25(11):3376-84.
2007: Chan Nguyen; Akinori Nishi; Janice W Kansy; Joseph Fernandez; Kanehiro Hayashi; Frank Gillardon; Hugh C Hemmings; Angus Nairn; James A Bibb
Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.
The Journal of biological chemistry 2007;282(22):16511-20.
2007: Nataliya V Uboha; Marc Flajolet; Angus Nairn; Marina R Picciotto
A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(16):4413-23.
2007: Marc Flajolet; Gen He; Myriam Heiman; Angie Lin; Angus Nairn; Paul Greengard
Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):4159-64.
2007: Matthew S Kelker; Barbara Dancheck; Tingting Ju; Rene P Kessler; Jebecka Hudak; Angus Nairn; Wolfgang Peti
Structural basis for spinophilin-neurabin receptor interaction.
Biochemistry 2007;46(9):2333-44.
2007: Jung-Hyuck Ahn; Thomas McAvoy; Sergey V Rakhilin; Akinori Nishi; Paul Greengard; Angus Nairn
Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2979-84.
2007: Akira Iizuka; Kumiko Sengoku; Masumi Iketani; Fumio Nakamura; Yasufumi Sato; Masayuki Matsushita; Angus Nairn; Ken Takamatsu; Yoshio Goshima; Kohtaro Takei
Calcium-induced synergistic inhibition of a translational factor eEF2 in nerve growth cones.
Biochemical and biophysical research communications 2007;353(2):244-50.
2007: Maïté Hotte; Sébastien Thuault; Kelly T Dineley; Hugh C Hemmings; Angus Nairn; Thérèse M Jay
Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo.
Synapse (New York, N.Y.) 2007;61(1):24-8.
2006: Christian Hansen; Paul Greengard; Angus Nairn; Tommy Andersson; Wolfgang F Vogel
Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1.
Experimental cell research 2006;312(20):4011-8.
2006: Tambudzai Kanhema; Grethe Dagestad; Debabrata Panja; Adrian Tiron; Elhoucine Messaoudi; Bjarte Håvik; Shui-Wang Ying; Angus Nairn; Nahum Sonenberg; Clive R Bramham
Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control.
Journal of neurochemistry 2006;99(5):1328-37.
2006: Seth S Margolis; Jennifer A. Perry; Craig M Forester; Leta K Nutt; Yanxiang Guo; Melanie J Jardim; Michael J. Thomenius; Christopher Freel; Rashid Darbandi; Jung-Hyuck Ahn; Jason Arroyo; Xiao-Fan Wang; Shirish Shenolikar; Angus Nairn; William G Dunphy; William C Hahn; David M Virshup; Sally Kornbluth
Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis.
Cell 2006;127(4):759-73.
2006: László Csanády; Angus Nairn; David C Gadsby
Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle.
The Journal of general physiology 2006;128(5):523-33.
2006: Dilja D Krueger; Jessica L Howell; Britni F Hebert; Peter Olausson; Jane R Taylor; Angus Nairn
Assessment of cognitive function in the heterozygous reeler mouse.
Psychopharmacology 2006;189(1):95-104.
2006: Martin Mense; Paola Vergani; Dennis M White; Gal Altberg; Angus Nairn; David C Gadsby
In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer.
The EMBO journal 2006;25(20):4728-39.
2006: Bogachan Sahin; Hongjun Shu; Joseph Fernandez; Ali El-Armouche; Jeffery D Molkentin; Angus Nairn; James A Bibb
Phosphorylation of protein phosphatase inhibitor-1 by protein kinase C.
The Journal of biological chemistry 2006;281(34):24322-35.
2006: Yong Kim; Jee Young Sung; Ilaria Ceglia; Ko-Woon Lee; Jung-Hyuck Ahn; Jonathan M Halford; Amie M Kim; Seung P Kwak; Jong Bae Park; Sung Ho Ryu; Annette Schenck; Barbara Bardoni; John D Scott; Angus Nairn; Paul Greengard
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology.
Nature 2006;442(7104):814-7.
2006: Steven P Braithwaite; Surojit Paul; Angus Nairn; Paul J Lombroso
Synaptic plasticity: one STEP at a time.
Trends in neurosciences 2006;29(8):452-8.
2006: Maïté Hotte; Sébastien Thuault; Fabienne Lachaise; Kelly T Dineley; Hugh C Hemmings; Angus Nairn; Thérèse M Jay
D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex.
Behavioural brain research 2006;171(1):127-33.
2006: Jessica P Rogers; Albert E. Beuscher; Marc Flajolet; Thomas McAvoy; Angus Nairn; Arthur J Olson; Paul Greengard
Discovery of protein phosphatase 2C inhibitors by virtual screening.
Journal of medicinal chemistry 2006;49(5):1658-67.
2006: Yong Zhang; Per Svenningsson; Roberto Picetti; Stefan D Schlussman; Angus Nairn; Ann Ho; Paul Greengard; Mary Jeanne Kreek
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(10):2645-51.
2006: Venetia Zachariou; Véronique Sgambato-Faure; Teresa Sasaki; Per Svenningsson; Olivier Berton; Allen Fienberg; Angus Nairn; Paul Greengard; Eric J Nestler
Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(3):555-62.
2006: Ko-Woon Lee; Yong Kim; Amie M Kim; Kathryn Helmin; Angus Nairn; Paul Greengard
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3399-404.
2006: Oren S Rosenberg; Sebastian Deindl; Luis R Comolli; André Hoelz; Kenneth H Downing; Angus Nairn; John Kuriyan
Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II.
The FEBS journal 2006;273(4):682-94.
2006: Marion Maus; Yvette Torrens; Christian Gauchy; Sylvie Bretin; Angus Nairn; Jacques Glowinski; Joel Premont
2-Deoxyglucose and NMDA inhibit protein synthesis in neurons and regulate phosphorylation of elongation factor-2 by distinct mechanisms.
Journal of neurochemistry 2006;96(3):815-24.
2006: Lena Scott; Sergey Zelenin; Seth Malmersjö; Jacob M Kowalewski; Eivor Zettergren Markus; Angus Nairn; Paul Greengard; hjalmar brismar; Anita Aperia
Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(3):762-7.
2005: Mi Jin; Helen Bateup; Júlio C Padovan; Paul Greengard; Angus Nairn; Brian T Chait
Quantitative analysis of protein phosphorylation in mouse brain by hypothesis-driven multistage mass spectrometry.
Analytical chemistry 2005;77(24):7845-51.
2005: Oren S Rosenberg; Sebastian Deindl; Rou-Jia Sung; Angus Nairn; John Kuriyan
Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme.
Cell 2005;123(5):849-60.
2005: Ken Uematsu; Marie Futter; Linda C Hsieh-Wilson; Hideho Higashi; Hisao Maeda; Angus Nairn; Paul Greengard; Akinori Nishi
Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways.
Journal of neurochemistry 2005;95(6):1642-52.
2005: Jill R Bordelon; Yoland Smith; Angus Nairn; Roger J Colbran; Paul Greengard; E Chris Muly
Differential localization of protein phosphatase-1alpha, beta and gamma1 isoforms in primate prefrontal cortex.
Cerebral cortex (New York, N.Y. : 1991) 2005;15(12):1928-37.
2005: Katya Belelovsky; Alina Elkobi; Hanoch Kaphzan; Angus Nairn; Kobi Rosenblum
A molecular switch for translational control in taste memory consolidation.
The European journal of neuroscience 2005;22(10):2560-8.
2005: J Ashot Kozak; Masayuki Matsushita; Angus Nairn; Michael D Cahalan
Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels.
The Journal of general physiology 2005;126(5):499-514.
2005: Wen Yeshao; Jiali Gu; Xianghong Peng; Angus Nairn; Jerry L Nadler
Elevated glucose activates protein synthesis in cultured cardiac myocytes.
Metabolism: clinical and experimental 2005;54(11):1453-60.
2005: Paola Vergani; C Basso; M Mense; Angus Nairn; David C Gadsby
Control of the CFTR channel's gates.
Biochemical Society transactions 2005;33(Pt 5):1003-7.
2005: Miho Hamada; Joseph P Hendrick; Gregory R Ryan; Mahomi Kuroiwa; Hideho Higashi; Masatoshi Tanaka; Angus Nairn; Paul Greengard; Akinori Nishi
Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons.
The Journal of pharmacology and experimental therapeutics 2005;315(2):872-8.
2005: Eric M Snyder; Yi Nong; Claudia Almeida; Surojit Paul; Timothy Moran; Eun Young Choi; Angus Nairn; Michael W Salter; Paul J Lombroso; Gunnar K Gouras; Paul Greengard
Regulation of NMDA receptor trafficking by amyloid-beta.
Nature neuroscience 2005;8(8):1051-8.
2005: Xiaozhou P Ryan; Jacqueline Alldritt; Per Svenningsson; Patrick B Allen; Gang-Yi Wu; Angus Nairn; Paul Greengard
The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology.
Neuron 2005;47(1):85-100.
2005: Masayuki Matsushita; J Ashot Kozak; Yoshio Shimizu; Derek T McLachlin; Hiroto Yamaguchi; Fan-Yan Wei; Kazuhito Tomizawa; Hideki Matsui; Brian T Chait; Michael D Cahalan; Angus Nairn
Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1.
The Journal of biological chemistry 2005;280(21):20793-803.
2005: Sabine Hilfiker; Fabio Benfenati; Frédéric Doussau; Angus Nairn; Andrew J Czernik; George J Augustine; Paul Greengard
Structural domains involved in the regulation of transmitter release by synapsins.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2658-69.
2005: Marie Futter; Ken Uematsu; Stewart A Bullock; Yong Kim; Hugh C Hemmings; Akinori Nishi; Paul Greengard; Angus Nairn
Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).
Proceedings of the National Academy of Sciences of the United States of America 2005;102(9):3489-94.
2005: Sang Yoon Lee; Sergey V Voronov; Kresimir Letinic; Angus Nairn; Gilbert Di Paolo; Pietro De Camilli
Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases.
The Journal of cell biology 2005;168(5):789-99.
2005: Paola Vergani; Steve W Lockless; Angus Nairn; David C Gadsby
CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains.
Nature 2005;433(7028):876-80.
2005: Satoru Takahashi; Toshio Ohshima; Andrew Cho; Taduru Sreenath; Michael Iadarola; Varsha Shukla; Yong Kim; Angus Nairn; Roscoe O Brady; Paul Greengard; Ashok Kulkarni
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1737-42.
2005: László Csanády; Donna Seto-Young; Kim W Chan; Cristina Cenciarelli; Benjamin B Angel; Jun Qin; Derek T McLachlin; Andrew N Krutchinsky; Brian T Chait; Angus Nairn; David C Gadsby
Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.
The Journal of general physiology 2005;125(2):171-86.
2005: Akinori Nishi; Yasuo Watanabe; Hideho Higashi; Masatoshi Tanaka; Angus Nairn; Paul Greengard
Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(4):1199-204.
2005: Emmanuel Valjent; Vincent Pascoli; Per Svenningsson; Surojit Paul; hervé enslen; Jean-Christophe Corvol; Alexandre Stipanovich; Jocelyne Caboche; Paul J Lombroso; Angus Nairn; Paul Greengard; Denis Hervé; Jean-Antoine Girault
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):491-6.
2005: Per Svenningsson; Angus Nairn; Paul Greengard
DARPP-32 mediates the actions of multiple drugs of abuse.
The AAPS journal 2005;7(2):E353-60.
2005: László Csanády; Kim W Chan; Angus Nairn; David C Gadsby
Functional roles of nonconserved structural segments in CFTR's NH2-terminal nucleotide binding domain.
The Journal of general physiology 2005;125(1):43-55.
2004: Sergey V Rakhilin; Patricia A Olson; Akinori Nishi; N N Starkova; Allen Fienberg; Angus Nairn; Dalton Surmeier; Paul Greengard
A network of control mediated by regulator of calcium/calmodulin-dependent signaling.
Science (New York, N.Y.) 2004;306(5696):698-701.
2004: Bogachan Sahin; Janice W Kansy; Angus Nairn; Jozef Spychala; Steven E Ealick; Allen Fienberg; Robert W Greene; James A Bibb
Molecular characterization of recombinant mouse adenosine kinase and evaluation as a target for protein phosphorylation.
European journal of biochemistry / FEBS 2004;271(17):3547-55.
2004: Miho Hamada; Hideho Higashi; Angus Nairn; Paul Greengard; Akinori Nishi
Differential regulation of dopamine D1 and D2 signaling by nicotine in neostriatal neurons.
Journal of neurochemistry 2004;90(5):1094-103.
2004: Stacie D Grossman; Marie Futter; Gretchen L Snyder; Patrick B Allen; Angus Nairn; Paul Greengard; Linda C Hsieh-Wilson
Spinophilin is phosphorylated by Ca2+/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin.
Journal of neurochemistry 2004;90(2):317-24.
2004: Diann R Stedman; Nataliya V Uboha; T Stedman; Angus Nairn; Marina R Picciotto
Cytoplasmic localization of calcium/calmodulin-dependent protein kinase I-alpha depends on a nuclear export signal in its regulatory domain.
FEBS letters 2004;566(1-3):275-80.
2004: Thomas C Vary; Angus Nairn; Charles H Lang
Restoration of protein synthesis in heart and skeletal muscle after withdrawal of alcohol.
Alcoholism, clinical and experimental research 2004;28(4):517-25.
2004: Ta-Hsien Lin; Yi-Choang Huang; Mei-ling Chin; Yi-chen Chen; Hao-Hsuan Jeng; Fang-Min Lin; Ming-Shi Shiao; Atsuko Horiuchi; Paul Greengard; Angus Nairn; Hsien-Bin Huang
1H, 15N, and 13C resonance assignments of DARPP-32 (dopamine and cAMP-regulated phosphoprotein, Mr. 32,000)--a protein inhibitor of protein phosphatase-1.
Journal of biomolecular NMR 2004;28(4):413-4.
2004: Julian C Braz; Kimberly Gregory; Anand Pathak; Wen Zhao; Bogachan Sahin; Raisa Klevitsky; Thomas F Kimball; John N Lorenz; Angus Nairn; Stephen B Liggett; Ilona Bodi; Su Wang; Arnold Schwartz; Edward G Lakatta; Anna A DePaoli-Roach; Jeffrey Robbins; Timothy E Hewett; James A Bibb; Margaret V Westfall; Evangelia G Kranias; Jeffery D Molkentin
PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Nature medicine 2004;10(3):248-54.
2004: Sang Yoon Lee; Markus R Wenk; Yong Kim; Angus Nairn; Pietro De Camilli
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):546-51.
2004: Kenneth Williams; Terence Wu; Christopher Colangelo; Angus Nairn
Recent advances in neuroproteomics and potential application to studies of drug addiction.
Neuropharmacology 2004;47 Suppl 1():148-66.
2004: Angus Nairn; Per Svenningsson; Akinori Nishi; Gilberto Fisone; Jean-Antoine Girault; Paul Greengard
The role of DARPP-32 in the actions of drugs of abuse.
Neuropharmacology 2004;47 Suppl 1():14-23.
2004: Per Svenningsson; Akinori Nishi; Gilberto Fisone; Jean-Antoine Girault; Angus Nairn; Paul Greengard
DARPP-32: an integrator of neurotransmission.
Annual review of pharmacology and toxicology 2004;44():269-96.
2003: Marc Flajolet; Sergey V Rakhilin; Hong Wang; Natalia Starkova; Nina Nuangchamnong; Angus Nairn; Paul Greengard
Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):16006-11.
2003: Ryuichi Fukui; Per Svenningsson; Toyojiro Matsuishi; Hideho Higashi; Angus Nairn; Paul Greengard; Akinori Nishi
Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice.
Journal of neurochemistry 2003;87(6):1391-401.
2003: Gretchen L Snyder; Stacey Galdi; Allen Fienberg; Patrick Allen; Angus Nairn; Paul Greengard
Regulation of AMPA receptor dephosphorylation by glutamate receptor agonists.
Neuropharmacology 2003;45(6):703-13.
2003: Claudia Basso; Paola Vergani; Angus Nairn; David C Gadsby
Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating.
The Journal of general physiology 2003;122(3):333-48.
2003: Véronique Sgambato; Raia Minassian; Angus Nairn; Steven E Hyman
Regulation of ania-6 splice variants by distinct signaling pathways in striatal neurons.
Journal of neurochemistry 2003;86(1):153-64.
2003: Limei Yan; Angus Nairn; H Clive Palfrey; Matthew J Brady
Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells.
The Journal of biological chemistry 2003;278(20):18177-83.
2003: David A Colby; Wen Liu; James E Sheppeck; Hsien-Bin Huang; Angus Nairn; A Richard Chamberlin
A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure.
Bioorganic & medicinal chemistry letters 2003;13(9):1601-5.
2003: Wen Liu; James E Sheppeck; David A Colby; Hsien-Bin Huang; Angus Nairn; A Richard Chamberlin
The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity.
Bioorganic & medicinal chemistry letters 2003;13(9):1597-600.
2003: André Hoelz; Angus Nairn; John Kuriyan
Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II.
Molecular cell 2003;11(5):1241-51.
2003: Young-Mi Kim; Takuo Watanabe; Patrick B Allen; Young-Myoung Kim; Shin-Jeong Lee; Paul Greengard; Angus Nairn; Young-Guen Kwon
PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation.
The Journal of biological chemistry 2003;278(16):13819-28.
2003: Akinori Nishi; Feng Liu; Seiichiro Matsuyama; Miho Hamada; Hideho Higashi; Angus Nairn; Paul Greengard
Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):1322-7.
2003: Linda C Hsieh-Wilson; Fabio Benfenati; Gretchen L Snyder; Patrick B Allen; Angus Nairn; Paul Greengard
Phosphorylation of spinophilin modulates its interaction with actin filaments.
The Journal of biological chemistry 2003;278(2):1186-94.
2003: Takuo Watanabe; Edgar F da Cruz e Silva; Hsien-Bin Huang; Natalia Starkova; Young-Guen Kwon; Atsuko Horiuchi; Paul Greengard; Angus Nairn
Preparation and characterization of recombinant protein phosphatase 1.
Methods in enzymology 2003;366():321-38.
2003: JK Chotiner; H Khorasani; Angus Nairn; Thomas J O'Dell; Joseph B Watson
Adenylyl cyclase-dependent form of chemical long-term potentiation triggers translational regulation at the elongation step.
Neuroscience 2003;116(3):743-52.
2003: Paola Vergani; Angus Nairn; David C Gadsby
On the mechanism of MgATP-dependent gating of CFTR Cl- channels.
The Journal of general physiology 2003;121(1):17-36.
2003: Shogo Endo; Angus Nairn; Paul Greengard; Masao Ito
Thr123 of rat G-substrate contributes to its action as a protein phosphatase inhibitor.
Neuroscience research 2003;45(1):79-89.
2003: Surojit Paul; Angus Nairn; Ping Wang; Paul J Lombroso
NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling.
Nature neuroscience 2003;6(1):34-42.
2002: Thomas C Vary; Angus Nairn; Gina Deiter; Charles H Lang
Differential effects of alcohol consumption on eukaryotic elongation factors in heart, skeletal muscle, and liver.
Alcoholism, clinical and experimental research 2002;26(12):1794-802.
2002: Feng Liu; David M Virshup; Angus Nairn; Paul Greengard
Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors.
The Journal of biological chemistry 2002;277(47):45393-9.
2002: Nina Irwin; Steven Chao; Luda Goritchenko; Atsuko Horiuchi; Paul Greengard; Angus Nairn; Larry I Benowitz
Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12427-31.
2002: mehrdad alirezaei; Elodie Mordelet; Nathalie Rouach; Angus Nairn; Jacques Glowinski; Joël Prémont
Zinc-induced inhibition of protein synthesis and reduction of connexin-43 expression and intercellular communication in mouse cortical astrocytes.
The European journal of neuroscience 2002;16(6):1037-44.
2002: Maria Lindskog; Per Svenningsson; Laura Pozzi; Yong Kim; Allen Fienberg; James A Bibb; Bertil B. Fredholm; Angus Nairn; Paul Greengard; Gilberto Fisone
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine.
Nature 2002;418(6899):774-8.
2002: Marina S Feschenko; Elizabeth Stevenson; Angus Nairn; Kathleen J Sweadner
A novel cAMP-stimulated pathway in protein phosphatase 2A activation.
The Journal of pharmacology and experimental therapeutics 2002;302(1):111-8.
2002: Athanasios G Dousmanis; Angus Nairn; David C Gadsby
Distinct Mg(2+)-dependent steps rate limit opening and closing of a single CFTR Cl(-) channel.
The Journal of general physiology 2002;119(6):545-59.
2002: James K Kranz; Eun K Lee; Angus Nairn; A Joshua Wand
A direct test of the reductionist approach to structural studies of calmodulin activity: relevance of peptide models of target proteins.
The Journal of biological chemistry 2002;277(19):16351-4.
2002: Akinori Nishi; James A Bibb; Seiichiro Matsuyama; Miho Hamada; Hideho Higashi; Angus Nairn; Paul Greengard
Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A.
Journal of neurochemistry 2002;81(4):832-41.
2002: Lucia Pastorino; Annat F Ikin; Angus Nairn; Amit Pursnani; Joseph Buxbaum
The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta).
Molecular and cellular neurosciences 2002;19(2):175-85.
2002: Charles H Lang; Robert A Frost; Angus Nairn; David A MacLean; Thomas C Vary
TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation.
American journal of physiology. Endocrinology and metabolism 2002;282(2):E336-47.
2002: Christian Gauchy; Angus Nairn; Jacques Glowinski; Joël Prémont
N-Methyl-D-aspartate receptor activation inhibits protein synthesis in cortical neurons independently of its ionic permeability properties.
Neuroscience 2002;114(4):859-67.
2002: Stacie D Grossman; Linda C Hsieh-Wilson; Patrick B Allen; Angus Nairn; Paul Greengard
The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines.
Neuromolecular medicine 2002;2(1):61-9.
2001: Angus Nairn; Paul Greengard
A novel cyclin provides a link between dopamine and RNA processing.
Neuron 2001;32(2):174-6.
2001: Jasmina Jovanovic; T S Sihra; Angus Nairn; Hugh C Hemmings; Paul Greengard; Andrew J Czernik
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(20):7944-53.
2001: Feng Liu; X H Ma; Jernej Ule; James A Bibb; Akinori Nishi; A J DeMaggio; Zhen Yan; Angus Nairn; Paul Greengard
Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(20):11062-8.
2001: Y Chen; M Matsushita; Angus Nairn; Z Damuni; Decheng Cai; KU Frerichs; John M Hallenbeck
Mechanisms for increased levels of phosphorylation of elongation factor-2 during hibernation in ground squirrels.
Biochemistry 2001;40(38):11565-70.
2001: Sonja Althausen; Thorsten Mengesdorf; Günter Mies; Laszlo Oláh; Angus Nairn; C G Proud; Wulf Paschen
Changes in the phosphorylation of initiation factor eIF-2alpha, elongation factor eEF-2 and p70 S6 kinase after transient focal cerebral ischaemia in mice.
Journal of neurochemistry 2001;78(4):779-87.
2001: Allen Everett; Tamara D Stoops; Angus Nairn; David L Brautigan
Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes.
American journal of physiology. Heart and circulatory physiology 2001;281(1):H161-7.
2001: H Yamaguchi; M Matsushita; Angus Nairn; John Kuriyan
Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity.
Molecular cell 2001;7(5):1047-57.
2001: James A Bibb; Akinori Nishi; JP O'Callaghan; Jernej Ule; M Lan; Gretchen L Snyder; A Horiuchi; T Saito; Shin-ichi Hisanaga; Andrew J Czernik; Angus Nairn; Paul Greengard
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.
The Journal of biological chemistry 2001;276(17):14490-7.
2001: Hsien-Bin Huang; Yi-chen Chen; Atsuko Horiuchi; Li-Huei Tsai; H T Liu; Chia-Lin Chyan; M J Hsieh; C K Liu; Fang-Min Lin; Paul Greengard; Angus Nairn; Ming-Shi Shiao; Ta-Hsien Lin
Backbone 1H, 15N, and 13C resonance assignments of ARPP-19.
Journal of biomolecular NMR 2001;19(4):383-4.
2001: J Kisielow; Angus Nairn; Klaus Karjalainen
TARPP, a novel protein that accompanies TCR gene rearrangement and thymocyte education.
European journal of immunology 2001;31(4):1141-9.
2001: I Dulubova; A Horiuchi; Gretchen L Snyder; Jean-Antoine Girault; Andrew J Czernik; L Shao; R Ramabhadran; Paul Greengard; Angus Nairn
ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins.
Journal of neurochemistry 2001;77(1):229-38.
2001: James A Bibb; Jiayun Chen; J R Taylor; Per Svenningsson; Akinori Nishi; Gretchen L Snyder; Zhen Yan; Z K Sagawa; Charles C Ouimet; Angus Nairn; Eric J Nestler; Paul Greengard
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.
Nature 2001;410(6826):376-80.
2001: T Watanabe; HB Huang; A Horiuchi; E F da Cruze Silva; Linda C Hsieh-Wilson; Patrick B Allen; Shirish Shenolikar; Paul Greengard; Angus Nairn
Protein phosphatase 1 regulation by inhibitors and targeting subunits.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3080-5.
2001: mehrdad alirezaei; Philippe Marin; Angus Nairn; Jacques Glowinski; Joël Prémont
Inhibition of protein synthesis in cortical neurons during exposure to hydrogen peroxide.
Journal of neurochemistry 2001;76(4):1080-8.
2001: Imre Lengyel; Angus Nairn; A McCluskey; Gábor Tóth; B Penke; John A P Rostas
Auto-inhibition of Ca(2+)/calmodulin-dependent protein kinase II by its ATP-binding domain.
Journal of neurochemistry 2001;76(4):1066-72.
2001: Seong Hwan Kim; Angus Nairn; Nigel J Cairns; Gert Lubec
Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease.
Journal of neural transmission. Supplementum 2001;(61):263-72.
2001: Angus Nairn; M Matsushita; K Nastiuk; A Horiuchi; K Mitsui; Y Shimizu; H C Palfrey
Elongation factor-2 phosphorylation and the regulation of protein synthesis by calcium.
Progress in molecular and subcellular biology 2001;27():91-129.
2000: Akinori Nishi; James A Bibb; Gretchen L Snyder; Hideho Higashi; Angus Nairn; Paul Greengard
Amplification of dopaminergic signaling by a positive feedback loop.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12840-5.
2000: László Csanády; Kim W Chan; Donna Seto-Young; D C Kopsco; Angus Nairn; David C Gadsby
Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains.
The Journal of general physiology 2000;116(3):477-500.
2000: Koichi Iijima; K Ando; S Takeda; Y Satoh; T Seki; Shigeyoshi Itohara; Paul Greengard; Yutaka Kirino; Angus Nairn; Takahiro Suzuki
Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.
Journal of neurochemistry 2000;75(3):1085-91.
2000: Hsien-Bin Huang; Yi-chen Chen; Li-Huei Tsai; H Wang; Fang-Min Lin; Atsuko Horiuchi; Paul Greengard; Angus Nairn; Ming-Shi Shiao; Ta-Hsien Lin
Backbone 1H, 15N, and 13C resonance assignments of inhibitor-2 -- a protein inhibitor of protein phosphatase-1.
Journal of biomolecular NMR 2000;17(4):359-60.
2000: Kim W Chan; László Csanády; Donna Seto-Young; Angus Nairn; David C Gadsby
Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain.
The Journal of general physiology 2000;116(2):163-80.
2000: S Paul; G L Snyder; H Yokakura; Marina R Picciotto; Angus Nairn; Paul J Lombroso
The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(15):5630-8.
2000: S I Cho; M Koketsu; H Ishihara; M Matsushita; Angus Nairn; H Fukazawa; Y Uehara
Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor-2 kinase.
Biochimica et biophysica acta 2000;1475(3):207-15.
2000: G L Caporaso; James A Bibb; Gretchen L Snyder; C Valle; Sergey V Rakhilin; Allen Fienberg; Hugh C Hemmings; Angus Nairn; Paul Greengard
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia.
Neuropharmacology 2000;39(9):1637-44.
2000: John H Connor; D Frederick; H b Huang; Jinzeng Yang; Nicholas R Helps; Patricia T W Cohen; Angus Nairn; A DePaoli-Roach; Kelly Tatchell; Shirish Shenolikar
Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit.
The Journal of biological chemistry 2000;275(25):18670-5.
2000: Gretchen L Snyder; Patrick B Allen; Allen Fienberg; C G Valle; Richard Huganir; Angus Nairn; Paul Greengard
Regulation of phosphorylation of the GluR1 AMPA receptor in the neostriatum by dopamine and psychostimulants in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(12):4480-8.
2000: James A Bibb; Zhen Yan; Per Svenningsson; Gretchen L Snyder; Vincent A Pieribone; A Horiuchi; Angus Nairn; A Messer; Paul Greengard
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6809-14.
2000: Marina Zelenina; Birgitte Mønster Christensen; J Palmér; Angus Nairn; Søren Nielsen; Anita Aperia
Prostaglandin E(2) interaction with AVP: effects on AQP2 phosphorylation and distribution.
American journal of physiology. Renal physiology 2000;278(3):F388-94.
2000: Alfred Scheetz; Angus Nairn; Martha Constantine-Paton
NMDA receptor-mediated control of protein synthesis at developing synapses.
Nature neuroscience 2000;3(3):211-6.
2000: James B Aggen; Angus Nairn; Richard Chamberlin
Regulation of protein phosphatase-1.
Chemistry & biology 2000;7(1):R13-23.
1999: James A Bibb; Gretchen L Snyder; Akinori Nishi; Zhen Yan; Laurent Meijer; Allen Fienberg; Li-Huei Tsai; Y T Kwon; Jean-Antoine Girault; Andrew J Czernik; Richard Huganir; Hugh C Hemmings; Angus Nairn; Paul Greengard
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.
Nature 1999;402(6762):669-71.
1999: mehrdad alirezaei; Angus Nairn; Jacques Glowinski; Joël Prémont; Philippe Marin
Zinc inhibits protein synthesis in neurons. Potential role of phosphorylation of translation initiation factor-2alpha.
The Journal of biological chemistry 1999;274(45):32433-8.
1999: ND Lawson; M Zain; Theresa Zibello; Marina R Picciotto; Angus Nairn; Nancy Berliner
Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturation.
Experimental hematology 1999;27(11):1682-90.
1999: Akinori Nishi; Gilberto Fisone; Gretchen L Snyder; I Dulubova; Anita Aperia; Angus Nairn; Paul Greengard
Regulation of Na+, K+-ATPase isoforms in rat neostriatum by dopamine and protein kinase C.
Journal of neurochemistry 1999;73(4):1492-501.
1999: T McAvoy; P B Allen; H Obaishi; H Nakanishi; Y Takai; Paul Greengard; Angus Nairn; Hugh C Hemmings
Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.
Biochemistry 1999;38(39):12943-9.
1999: T Tsumura; A Murata; F Yamaguchi; K Sugimoto; Eiichi Hasegawa; O Hatase; Angus Nairn; M Tokuda
The expression of Ca2+/calmodulin-dependent protein kinase I in rat retina is regulated by light stimulation.
Vision research 1999;39(19):3165-73.
1999: H Chung; Angus Nairn; K Murata; David L Brautigan
Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2.
Biochemistry 1999;38(32):10371-6.
1999: Paul Greengard; Patrick B Allen; Angus Nairn
Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade.
Neuron 1999;23(3):435-47.
1999: Akinori Nishi; Gretchen L Snyder; Allen Fienberg; Gilberto Fisone; Anita Aperia; Angus Nairn; Paul Greengard
Requirement for DARPP-32 in mediating effect of dopamine D2 receptor activation.
The European journal of neuroscience 1999;11(7):2589-92.
1999: S X Jun Cheng; Oleg Aizman; Angus Nairn; Paul Greengard; Anita Aperia
[Ca2+]i determines the effects of protein kinases A and C on activity of rat renal Na+,K+-ATPase.
The Journal of physiology 1999;518 ( Pt 1)():37-46.
1999: E Maréchal; K Hiratsuka; J Delgado; Angus Nairn; J Qin; Brian T Chait; Nam-Hai Chua
Modulation of GT-1 DNA-binding activity by calcium-dependent phosphorylation.
Plant molecular biology 1999;40(3):373-86.
1999: K Ando; M Oishi; S Takeda; Koichi Iijima; T Isohara; Angus Nairn; Yutaka Kirino; Paul Greengard; Takahiro Suzuki
Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(11):4421-7.
1999: T Isohara; A Horiuchi; T Watanabe; K Ando; Andrew J Czernik; I Uno; Paul Greengard; Angus Nairn; Takahiro Suzuki
Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase.
Biochemical and biophysical research communications 1999;258(2):300-5.
1999: Akinori Nishi; Gretchen L Snyder; Angus Nairn; Paul Greengard
Role of calcineurin and protein phosphatase-2A in the regulation of DARPP-32 dephosphorylation in neostriatal neurons.
Journal of neurochemistry 1999;72(5):2015-21.
1999: Allen Fienberg; C Nordstedt; HG Belting; Andrew J Czernik; Angus Nairn; Sam Gandy; Paul Greengard; Frank H Ruddle
Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.
The Journal of experimental zoology 1999;285(1):76-84.
1999: M Matsushita; Angus Nairn
Inhibition of the Ca2+/calmodulin-dependent protein kinase I cascade by cAMP-dependent protein kinase.
The Journal of biological chemistry 1999;274(15):10086-93.
1999: Linda C Hsieh-Wilson; Patrick B Allen; T Watanabe; Angus Nairn; Paul Greengard
Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.
Biochemistry 1999;38(14):4365-73.
1999: Hsien-Bin Huang; A Horiuchi; T Watanabe; S R Shih; Huey-Jen Tsay; H C Li; Paul Greengard; Angus Nairn
Characterization of the inhibition of protein phosphatase-1 by DARPP-32 and inhibitor-2.
The Journal of biological chemistry 1999;274(12):7870-8.
1999: S Endo; M Suzuki; M Sumi; Angus Nairn; R Morita; K Yamakawa; Paul Greengard; M Ito
Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2467-72.
1999: James B Aggen; JM Humphrey; CM Gauss; Hsien-Bin Huang; Angus Nairn; A Richard Chamberlin
The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity.
Bioorganic & medicinal chemistry 1999;7(3):543-64.
1999: G Nishimoto; Marina Zelenina; D Li; M Yasui; Anita Aperia; Søren Nielsen; Angus Nairn
Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue.
The American journal of physiology 1999;276(2 Pt 2):F254-9.
1999: T Watanabe; Jun Sukegawa; I Sukegawa; S Tomita; Koichi Iijima; S Oguchi; Takahiro Suzuki; Angus Nairn; Paul Greengard
A 127-kDa protein (UV-DDB) binds to the cytoplasmic domain of the Alzheimer's amyloid precursor protein.
Journal of neurochemistry 1999;72(2):549-56.
1999: David C Gadsby; Angus Nairn
Regulation of CFTR Cl- ion channels by phosphorylation and dephosphorylation.
Advances in second messenger and phosphoprotein research 1999;33():79-106.
1999: Zhen Yan; Linda C Hsieh-Wilson; Jian Feng; K Tomizawa; Patrick B Allen; Allen Fienberg; Angus Nairn; Paul Greengard
Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP-32 and spinophilin.
Nature neuroscience 1999;2(1):13-7.
1999: David C Gadsby; Angus Nairn
Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.
Physiological reviews 1999;79(1 Suppl):S77-S107.
1998: Alberto E Pereda; T D Bell; Bill Hoon Chang; A J Czernik; Angus Nairn; Thomas R Soderling; Donald S Faber
Ca2+/calmodulin-dependent kinase II mediates simultaneous enhancement of gap-junctional conductance and glutamatergic transmission.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13272-7.
1998: M Matsushita; Angus Nairn
Characterization of the mechanism of regulation of Ca2+/ calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinase.
The Journal of biological chemistry 1998;273(34):21473-81.
1998: David C Gadsby; A G Dousmanis; Angus Nairn
ATP hydrolysis cycles and the gating of CFTR Cl- channels.
Acta physiologica Scandinavica. Supplementum 1998;643():247-56.
1998: Paul Greengard; Angus Nairn; Jean-Antoine Girault; Charles C Ouimet; Gretchen L Snyder; Gilberto Fisone; Patrick B Allen; Allen Fienberg; Akinori Nishi
The DARPP-32/protein phosphatase-1 cascade: a model for signal integration.
Brain research. Brain research reviews 1998;26(2-3):274-84.
1998: L M Matovcik; Angus Nairn; Fred S Gorelick
Cellular localization of calmodulin-dependent protein kinases I and II to A-cells and D-cells of the endocrine pancreas.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(4):519-26.
1998: F Wang; S Zeltwanger; IC Yang; Angus Nairn; Tzyh-Chang Hwang
Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating. Evidence for two binding sites with opposite effects.
The Journal of general physiology 1998;111(3):477-90.
1998: F Desdouits; JC Siciliano; Angus Nairn; Paul Greengard; Jean-Antoine Girault
Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons.
The Biochemical journal 1998;330 ( Pt 1)():211-6.
1998: Patrick B Allen; Y G Kwon; Angus Nairn; Paul Greengard
Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit.
The Journal of biological chemistry 1998;273(7):4089-95.
1998: J Desdouits-Magnen; F Desdouits; S Takeda; Li-Jyun Syu; Alan Saltiel; Joseph Buxbaum; Andrew J Czernik; Angus Nairn; Paul Greengard
Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade.
Journal of neurochemistry 1998;70(2):524-30.
1997: Alfred Scheetz; Angus Nairn; Martha Constantine-Paton
N-methyl-D-aspartate receptor activation and visual activity induce elongation factor-2 phosphorylation in amphibian tecta: a role for N-methyl-D-aspartate receptors in controlling protein synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14770-5.
1997: XJ Cheng; J O Höög; Angus Nairn; Paul Greengard; Anita Aperia
Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
The American journal of physiology 1997;273(6 Pt 1):C1981-6.
1997: MJ Brady; Angus Nairn; Alan Saltiel
The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action.
The Journal of biological chemistry 1997;272(47):29698-703.
1997: CM Gauss; James E Sheppeck; Angus Nairn; Richard Chamberlin
A molecular modeling analysis of the binding interactions between the okadaic acid class of natural product inhibitors and the Ser-Thr phosphatases, PP1 and PP2A.
Bioorganic & medicinal chemistry 1997;5(9):1751-73.
1997: Roger Belusa; Z M Wang; T Matsubara; B Sahlgren; I Dulubova; Angus Nairn; E Ruoslahti; Paul Greengard; Anita Aperia
Mutation of the protein kinase C phosphorylation site on rat alpha1 Na+,K+-ATPase alters regulation of intracellular Na+ and pH and influences cell shape and adhesiveness.
The Journal of biological chemistry 1997;272(32):20179-84.
1997: Juan C Sáez; Angus Nairn; A J Czernik; G I Fishman; david spray; Elliot L Hertzberg
Phosphorylation of connexin43 and the regulation of neonatal rat cardiac myocyte gap junctions.
Journal of molecular and cellular cardiology 1997;29(8):2131-45.
1997: Philippe Marin; K L Nastiuk; N Daniel; Jean-Antoine Girault; A J Czernik; Jacques Glowinski; Angus Nairn; Joël Prémont
Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(10):3445-54.
1997: Perry Blackshear; J Silver; Angus Nairn; Kathleen K Sulik; M V Squier; Deborah J Stumpo; J S Tuttle
Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.
Experimental neurology 1997;145(1):46-61.
1997: Takahiro Suzuki; K Ando; T Isohara; M Oishi; G S Lim; Y Satoh; Wilma Wasco; Rudolph E Tanzi; Angus Nairn; Paul Greengard; Sam Gandy; Yutaka Kirino
Phosphorylation of Alzheimer beta-amyloid precursor-like proteins.
Biochemistry 1997;36(15):4643-9.
1997: Y G Kwon; HB Huang; F Desdouits; Jean-Antoine Girault; Paul Greengard; Angus Nairn
Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3536-41.
1997: HB Huang; A Horiuchi; J Goldberg; Paul Greengard; Angus Nairn
Site-directed mutagenesis of amino acid residues of protein phosphatase 1 involved in catalysis and inhibitor binding.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):3530-5.
1997: Y G Kwon; Seok-Yong Lee; Yongwon Choi; Paul Greengard; Angus Nairn
Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2168-73.
1997: S Nowicki; S L Chen; Oleg Aizman; XJ Cheng; D Li; C Nowicki; Angus Nairn; Paul Greengard; Anita Aperia
20-Hydroxyeicosa-tetraenoic acid (20 HETE) activates protein kinase C. Role in regulation of rat renal Na+,K+-ATPase.
The Journal of clinical investigation 1997;99(6):1224-30.
1997: M Oishi; Angus Nairn; Andrew J Czernik; G S Lim; T Isohara; Sam Gandy; Paul Greengard; Takahiro Suzuki
The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.
Molecular medicine (Cambridge, Mass.) 1997;3(2):111-23.
1997: L T Nevalainen; T Aoyama; Mitsuhiko Ikura; A Crivici; H Yan; N H Chua; Angus Nairn
Characterization of novel calmodulin-binding peptides with distinct inhibitory effects on calmodulin-dependent enzymes.
The Biochemical journal 1997;321 ( Pt 1)():107-15.
1996: MW Marino; James D Dunbar; L W Wu; J R Ngaiza; H M Han; D Guo; M Matsushita; Angus Nairn; Y Zhang; Richard Kolesnick; E A Jaffe; David B Donner
Inhibition of tumor necrosis factor signal transduction in endothelial cells by dimethylaminopurine.
The Journal of biological chemistry 1996;271(45):28624-9.
1996: Perry Blackshear; Wi S Lai; J S Tuttle; Deborah J Stumpo; Elizabeth A Kennington; Angus Nairn; Kathleen K Sulik
Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency.
Brain research. Developmental brain research 1996;96(1-2):62-75.
1996: F Desdouits; Joseph Buxbaum; J Desdouits-Magnen; Angus Nairn; Paul Greengard
Amyloid beta peptide formation in cell-free preparations. Regulation by protein kinase C, calmodulin, and calcineurin.
The Journal of biological chemistry 1996;271(40):24670-4.
1996: John M Aletta; M A Selbert; Angus Nairn; Arthur M Edelman
Activation of a calcium-calmodulin-dependent protein kinase I cascade in PC12 cells.
The Journal of biological chemistry 1996;271(34):20930-4.
1996: N S Logvinenko; I Dulubova; Natalya U Fedosova; S H Larsson; Angus Nairn; M Esmann; Paul Greengard; Anita Aperia
Phosphorylation by protein kinase C of serine-23 of the alpha-1 subunit of rat Na+,K(+)-ATPase affects its conformational equilibrium.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):9132-7.
1996: Y Qian; D S Chao; D R Santillano; Trudy L Cornwell; Angus Nairn; Paul Greengard; T M Lincoln; David S Bredt
cGMP-dependent protein kinase in dorsal root ganglion: relationship with nitric oxide synthase and nociceptive neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(10):3130-8.
1996: J Goldberg; Angus Nairn; John Kuriyan
Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I.
Cell 1996;84(6):875-87.
1996: Marina R Picciotto; K L Nastiuk; Angus Nairn
Structure, regulation, and function of calcium/calmodulin-dependent protein kinase I.
Advances in pharmacology (San Diego, Calif.) 1996;36():251-75.
1995: P J French; Jan Bijman; Marcel Edixhoven; Arie B Vaandrager; Bob J Scholte; Suzanne M Lohmann; Angus Nairn; Hugo R de Jonge
Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein kinase II.
The Journal of biological chemistry 1995;270(44):26626-31.
1995: H Yokokura; Marina R Picciotto; Angus Nairn; H Hidaka
The regulatory region of calcium/calmodulin-dependent protein kinase I contains closely associated autoinhibitory and calmodulin-binding domains.
The Journal of biological chemistry 1995;270(40):23851-9.
1995: N Terada; K Takase; P Papst; Angus Nairn; Erwin W Gelfand
Rapamycin inhibits ribosomal protein synthesis and induces G1 prolongation in mitogen-activated T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3418-26.
1995: J Goldberg; H B Huang; Y G Kwon; Paul Greengard; Angus Nairn; John Kuriyan
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
Nature 1995;376(6543):745-53.
1995: Talvinder S Sihra; Angus Nairn; P Kloppenburg; Z Lin; C Pouzat
A role for calcineurin (protein phosphatase-2B) in the regulation of glutamate release.
Biochemical and biophysical research communications 1995;212(2):609-16.
1995: Marina R Picciotto; Michele Zoli; G Bertuzzi; Angus Nairn
Immunochemical localization of calcium/calmodulin-dependent protein kinase I.
Synapse (New York, N.Y.) 1995;20(1):75-84.
1995: F Desdouits; D Cohen; Angus Nairn; Paul Greengard; Jean-Antoine Girault
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo.
The Journal of biological chemistry 1995;270(15):8772-8.
1995: Maxwell T Hincke; Angus Nairn; W A Staines
Cystic fibrosis transmembrane conductance regulator is found within brain ventricular epithelium and choroid plexus.
Journal of neurochemistry 1995;64(4):1662-8.
1995: Dalton Surmeier; José Bargas; H C Hemmings; Angus Nairn; Paul Greengard
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.
Neuron 1995;14(2):385-97.
1995: F Desdouits; J J Cheetham; H B Huang; Y G Kwon; E F da Cruz e Silva; Patrice DENEFLE; M E Ehrlich; Angus Nairn; Paul Greengard; Jean-Antoine Girault
Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides.
Biochemical and biophysical research communications 1995;206(2):652-8.
1995: H C Palfrey; Angus Nairn
Calcium-dependent regulation of protein synthesis.
Advances in second messenger and phosphoprotein research 1995;30():191-223.
1994: N Terada; H R Patel; K Takase; K Kohno; Angus Nairn; Erwin W Gelfand
Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11477-81.
1994: David C Gadsby; Angus Nairn
Regulation of CFTR channel gating.
Trends in biochemical sciences 1994;19(11):513-8.
1994: Angus Nairn; Marina R Picciotto
Calcium/calmodulin-dependent protein kinases.
Seminars in cancer biology 1994;5(4):295-303.
1994: Paul Webster; L Vanacore; Angus Nairn; C R Marino
Subcellular localization of CFTR to endosomes in a ductal epithelium.
The American journal of physiology 1994;267(2 Pt 1):C340-8.
1994: M Dohadwala; E F da Cruz e Silva; Frederick L Hall; Richard Williams; D A Carbonaro-Hall; Angus Nairn; Paul Greengard; Norbert Berndt
Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6408-12.
1994: Tomomi Ito; H Yokokura; Angus Nairn; Yuji Nimura; H Hidaka
Ca2+/calmodulin-dependent protein kinase V and I may form a family of isoforms.
Biochemical and biophysical research communications 1994;201(3):1561-6.
1994: Alberto E Pereda; Angus Nairn; L R Wolszon; Donald S Faber
Postsynaptic modulation of synaptic efficacy at mixed synapses on the Mauthner cell.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(6):3704-12.
1994: Oivind Hvalby; H C Hemmings; O Paulsen; A J Czernik; Angus Nairn; J M Godfraind; Vidar Jensen; M Raastad; Johan F Storm; P Andersen
Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4761-5.
1994: T C Hwang; G Nagel; Angus Nairn; David C Gadsby
Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4698-702.
1994: S L Hyatt; L Liao; A Aderem; Angus Nairn; S Jaken
Correlation between protein kinase C binding proteins and substrates in REF52 cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(5):495-502.
1994: Thomas C Vary; Angus Nairn; Christopher J Lynch
Role of elongation factor 2 in regulating peptide-chain elongation in the heart.
The American journal of physiology 1994;266(4 Pt 1):E628-34.
1994: Gilberto Fisone; S X Cheng; Angus Nairn; Andrew J Czernik; Hugh C Hemmings; J O Höög; A M Bertorello; R Kaiser; T Bergman; H Jörnvall
Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.
The Journal of biological chemistry 1994;269(12):9368-73.
1994: T Suzuki; M Oishi; D R Marshak; Andrew J Czernik; Angus Nairn; Paul Greengard
Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein.
The EMBO journal 1994;13(5):1114-22.
1994: T Baukrowitz; T C Hwang; Angus Nairn; David C Gadsby
Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle.
Neuron 1994;12(3):473-82.
1994: David C Gadsby; T C Hwang; T Baukrowitz; G Nagel; Minoru Horie; Angus Nairn
Regulation of CFTR channel gating.
The Japanese journal of physiology 1994;44 Suppl 2():S183-92.
1993: David C Gadsby; T C Hwang; Minoru Horie; G Nagel; Angus Nairn
Cardiac chloride channels: incremental regulation by phosphorylation/dephosphorylation.
Annals of the New York Academy of Sciences 1993;707():259-74.
1993: Marina R Picciotto; Andrew J Czernik; Angus Nairn
Calcium/calmodulin-dependent protein kinase I. cDNA cloning and identification of autophosphorylation site.
The Journal of biological chemistry 1993;268(35):26512-21.
1993: Jonathan A Cohn; T V Strong; Marina R Picciotto; Angus Nairn; Francis S Collins; J Gregory Fitz
Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells.
Gastroenterology 1993;105(6):1857-64.
1993: Sam Gandy; G L Caporaso; Joseph Buxbaum; O de Cruz Silva; K Iverfeldt; C Nordstedt; T Suzuki; Andrew J Czernik; Angus Nairn; Paul Greengard
Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein.
Annals of the New York Academy of Sciences 1993;695():117-21.
1993: K Mitsui; M Brady; H Clive Palfrey; Angus Nairn
Purification and characterization of calmodulin-dependent protein kinase III from rabbit reticulocytes and rat pancreas.
The Journal of biological chemistry 1993;268(18):13422-33.
1993: D M Bagaglio; E H Cheng; F S Gorelick; K Mitsui; Angus Nairn; William N Hait
Phosphorylation of elongation factor 2 in normal and malignant rat glial cells.
Cancer research 1993;53(10 Suppl):2260-4.
1992: Sam Gandy; G L Caporaso; T V Ramabhadran; T Suzuki; Joseph Buxbaum; C Nordstedt; K Iverfeldt; Andrew J Czernik; Angus Nairn; Paul Greengard
Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine.
Annals of the New York Academy of Sciences 1992;674():203-17.
1992: G Nagel; T C Hwang; K L Nastiuk; Angus Nairn; David C Gadsby
The protein kinase A-regulated cardiac Cl- channel resembles the cystic fibrosis transmembrane conductance regulator.
Nature 1992;360(6399):81-4.
1992: G Johnson; J Gotlib; Vahram Haroutunian; L Bierer; Angus Nairn; Carl R Merril; W Wallace
Increased phosphorylation of elongation factor 2 in Alzheimer's disease.
Brain research. Molecular brain research 1992;15(3-4):319-26.
1992: Sam Gandy; Joseph Buxbaum; T Suzuki; T V Ramabhadran; G L Caporaso; Angus Nairn; Paul Greengard
The nature and metabolism of potentially amyloidogenic carboxyl-terminal fragments of the Alzheimer beta/A4-amyloid precursor protein: some technical notes.
Neurobiology of aging 1992;13(5):601-3.
1992: Hugh C Hemmings; Jean-Antoine Girault; Angus Nairn; G Bertuzzi; Paul Greengard
Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.
Journal of neurochemistry 1992;59(3):1053-61.
1992: Marina R Picciotto; Jonathan A Cohn; G Bertuzzi; Paul Greengard; Angus Nairn
Phosphorylation of the cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry 1992;267(18):12742-52.
1992: T Suzuki; Angus Nairn; Sam Gandy; Paul Greengard
Phosphorylation of Alzheimer amyloid precursor protein by protein kinase C.
Neuroscience 1992;48(4):755-61.
1992: Angus Nairn; Shirish Shenolikar
The role of protein phosphatases in synaptic transmission, plasticity and neuronal development.
Current opinion in neurobiology 1992;2(3):296-301.
1992: M Lin; Angus Nairn; Sandra E Guggino
cGMP-dependent protein kinase regulation of a chloride channel in T84 cells.
The American journal of physiology 1992;262(5 Pt 1):C1304-12.
1992: John H Hartwig; M Thelen; A Rosen; Paul A Janmey; Angus Nairn; A Aderem
MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin.
Nature 1992;356(6370):618-22.
1992: T C Hwang; Minoru Horie; Angus Nairn; David C Gadsby
Role of GTP-binding proteins in the regulation of mammalian cardiac chloride conductance.
The Journal of general physiology 1992;99(4):465-89.
1992: Maxwell T Hincke; Angus Nairn
Phosphorylation of elongation factor 2 during Ca(2+)-mediated secretion from rat parotid acini.
The Biochemical journal 1992;282 ( Pt 3)():877-82.
1992: Jonathan A Cohn; Angus Nairn; C R Marino; O Melhus; Jolanta Kole
Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2340-4.
1992: J L Countaway; Angus Nairn; Roger J Davis
Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.
The Journal of biological chemistry 1992;267(2):1129-40.
1992: Angus Nairn; A Aderem
Calmodulin and protein kinase C cross-talk: the MARCKS protein is an actin filament and plasma membrane cross-linking protein regulated by protein kinase C phosphorylation and by calmodulin.
Ciba Foundation symposium 1992;164():145-54; discussion 154-61.
1991: Alejandro M Bertorello; Anita Aperia; S I Walaas; Angus Nairn; Paul Greengard
Phosphorylation of the catalytic subunit of Na+,K(+)-ATPase inhibits the activity of the enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11359-62.
1991: J Neumann; Ramesh Gupta; W Schmitz; H Scholz; Angus Nairn; A M Watanabe
Evidence for isoproterenol-induced phosphorylation of phosphatase inhibitor-1 in the intact heart.
Circulation research 1991;69(6):1450-7.
1991: J Marshall; K A Martin; Marina R Picciotto; Susan Hockfield; Angus Nairn; Leonard K Kaczmarek
Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry 1991;266(33):22749-54.
1991: Paul Greengard; J Jen; Angus Nairn; C F Stevens
Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons.
Science (New York, N.Y.) 1991;253(5024):1135-8.
1991: E L Gustafson; Jean-Antoine Girault; Hugh C Hemmings; Angus Nairn; Paul Greengard
Immunocytochemical localization of phosphatase inhibitor-1 in rat brain.
The Journal of comparative neurology 1991;310(2):170-88.
1991: Jonathan M Graff; R R Rajan; Richard R Randall; Angus Nairn; Perry Blackshear
Protein kinase C substrate and inhibitor characteristics of peptides derived from the myristoylated alanine-rich C kinase substrate (MARCKS) protein phosphorylation site domain.
The Journal of biological chemistry 1991;266(22):14390-8.
1991: M Thelen; A Rosen; Angus Nairn; Alan Aderem
Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane.
Nature 1991;351(6324):320-2.
1991: Anita Aperia; J Fryckstedt; L Svensson; H C Hemmings; Angus Nairn; Paul Greengard
Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(7):2798-801.
1991: A J Czernik; J A Girault; Angus Nairn; J Chen; G Snyder; J Kebabian; Paul Greengard
Production of phosphorylation state-specific antibodies.
Methods in enzymology 1991;201():264-83.
1991: Shirish Shenolikar; Angus Nairn
Protein phosphatases: recent progress.
Advances in second messenger and phosphoprotein research 1991;23():1-121.
1990: Hugh C Hemmings; Angus Nairn; J I Elliott; Paul Greengard
Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.
The Journal of biological chemistry 1990;265(33):20369-76.
1990: A Rosen; K F Keenan; M Thelen; Angus Nairn; Alan Aderem
Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia.
The Journal of experimental medicine 1990;172(4):1211-5.
1990: Juan C Sáez; Angus Nairn; A J Czernik; david spray; Elliot L Hertzberg; Paul Greengard; Michael V L Bennett
Phosphorylation of connexin 32, a hepatocyte gap-junction protein, by cAMP-dependent protein kinase, protein kinase C and Ca2+/calmodulin-dependent protein kinase II.
European journal of biochemistry / FEBS 1990;192(2):263-73.
1990: M Thelen; A Rosen; Angus Nairn; Alan Aderem
Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5603-7.
1990: A Horiuchi; Kenneth R Williams; T Kurihara; Angus Nairn; Paul Greengard
Purification and cDNA cloning of ARPP-16, a cAMP-regulated phosphoprotein enriched in basal ganglia, and of a related phosphoprotein, ARPP-19.
The Journal of biological chemistry 1990;265(16):9476-84.
1990: D Demolle; M Lecomte; O Boutherin-Falson; E J Cragoe; Angus Nairn; Jean-Marie Boeynaems
Amiloride analogs induce the phosphorylation of elongation factor-2 in vascular endothelial cells.
Molecular pharmacology 1990;37(6):827-32.
1990: M J Brady; Angus Nairn; J A Wagner; H Clive Palfrey
Nerve growth factor-induced down-regulation of calmodulin-dependent protein kinase III in PC12 cells involves cyclic AMP-dependent protein kinase.
Journal of neurochemistry 1990;54(3):1034-9.
1990: Robert A Nichols; T S Sihra; Andrew J Czernik; Angus Nairn; Paul Greengard
Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes.
Nature 1990;343(6259):647-51.
1990: Angus Nairn
Role of Ca2+/calmodulin-dependent protein phosphorylation in signal transduction.
Advances in second messenger and phosphoprotein research 1990;24():202-5.
1989: Jean-Antoine Girault; Hugh C Hemmings; Kenneth R Williams; Angus Nairn; Paul Greengard
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.
The Journal of biological chemistry 1989;264(36):21748-59.
1989: D Piomelli; J K Wang; T S Sihra; Angus Nairn; Andrew J Czernik; Paul Greengard
Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8550-4.
1989: Björn Meister; J Fryckstedt; Martin Schalling; R Cortés; Tomas Hökfelt; Anita Aperia; H C Hemmings; Angus Nairn; M Ehrlich; Paul Greengard
Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8068-72.
1989: A Bahinski; Angus Nairn; Paul Greengard; David C Gadsby
Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes.
Nature 1989;340(6236):718-21.
1989: Richard Levenson; Angus Nairn; Perry Blackshear
Insulin rapidly induces the biosynthesis of elongation factor 2.
The Journal of biological chemistry 1989;264(20):11904-11.
1989: M Li; J D McCann; Matthew Peter Anderson; J P Clancy; C M Liedtke; Angus Nairn; Paul Greengard; M J Welsch
Regulation of chloride channels by protein kinase C in normal and cystic fibrosis airway epithelia.
Science (New York, N.Y.) 1989;244(4910):1353-6.
1989: A Rosen; Angus Nairn; Paul Greengard; Z A Cohn; Alan Aderem
Bacterial lipopolysaccharide regulates the phosphorylation of the 68K protein kinase C substrate in macrophages.
The Journal of biological chemistry 1989;264(16):9118-21.
1989: Ken Mackie; B C Sorkin; Angus Nairn; Paul Greengard; Gerald M Edelman; Bruce A Cunningham
Identification of two protein kinases that phosphorylate the neural cell-adhesion molecule, N-CAM.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(6):1883-96.
1989: Hugh C Hemmings; Angus Nairn; T L McGuinness; Richard Huganir; Paul Greengard
Role of protein phosphorylation in neuronal signal transduction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(5):1583-92.
1989: P J Conn; J A Strong; E M Azhderian; Angus Nairn; Paul Greengard; Leonard K Kaczmarek
Protein kinase inhibitors selectively block phorbol ester- or forskolin-induced changes in excitability of Aplysia neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(2):473-9.
1989: Ken Mackie; Angus Nairn; G Hampel; G Lam; E A Jaffe
Thrombin and histamine stimulate the phosphorylation of elongation factor 2 in human umbilical vein endothelial cells.
The Journal of biological chemistry 1989;264(3):1748-53.
1989: S Ivar Walaas; Angus Nairn
Multisite phosphorylation of microtubule-associated protein 2 (MAP-2) in rat brain: peptide mapping distinguishes between cyclic AMP-, calcium/calmodulin-, and calcium/phospholipid-regulated phosphorylation mechanisms.
Journal of molecular neuroscience : MN 1989;1(2):117-27.
1988: F S Gorelick; J K Wang; Y Lai; Angus Nairn; Paul Greengard
Autophosphorylation and activation of Ca2+/calmodulin-dependent protein kinase II in intact nerve terminals.
The Journal of biological chemistry 1988;263(33):17209-12.
1988: Perry Blackshear; Angus Nairn; J F Kuo
Protein kinases 1988: a current perspective.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(14):2957-69.
1988: G Thiel; Andrew J Czernik; F Gorelick; Angus Nairn; Paul Greengard
Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6337-41.
1988: S Ivar Walaas; Robert Horn; Angus Nairn; O Walaas; A Adler
Skeletal muscle sarcolemma proteins as targets for adenosine 3':5'-monophosphate-dependent and calcium-dependent protein kinases.
Archives of biochemistry and biophysics 1988;262(1):245-58.
1988: M Li; J D McCann; C M Liedtke; Angus Nairn; Paul Greengard; Michael J Welsh
Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium.
Nature 1988;331(6154):358-60.
1988: Angus Nairn; Hugh C Hemmings; S Ivar Walaas; Paul Greengard
DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.
Journal of neurochemistry 1988;50(1):257-62.
1988: G Weeks; Marina R Picciotto; Angus Nairn; S Ivar Walaas; Paul Greengard
Purification and characterization of PCPP-260: a Purkinje cell-enriched cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
Synapse (New York, N.Y.) 1988;2(1):89-96.
1987: Angus Nairn; H Clive Palfrey
Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2.
The Journal of biological chemistry 1987;262(36):17299-303.
1987: Angus Nairn; Robert A Nichols; M J Brady; H Clive Palfrey
Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.
The Journal of biological chemistry 1987;262(29):14265-72.
1987: K A Albert; Angus Nairn; Paul Greengard
The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(20):7046-50.
1987: Y Lai; Angus Nairn; F Gorelick; Paul Greengard
Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5710-4.
1987: H Clive Palfrey; Angus Nairn; Leslie L Muldoon; M L Villereal
Rapid activation of calmodulin-dependent protein kinase III in mitogen-stimulated human fibroblasts. Correlation with intracellular Ca2+ transients.
The Journal of biological chemistry 1987;262(20):9785-92.
1987: Nancy E Thomas; H N Bramson; Angus Nairn; Paul Greengard; D C Fry; A S Mildvan; E T Kaiser
Distinguishing among protein kinases by substrate specificities.
Biochemistry 1987;26(14):4471-4.
1987: T P Parks; Angus Nairn; Paul Greengard; J D Jamieson
The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins.
Archives of biochemistry and biophysics 1987;255(2):361-71.
1987: Angus Nairn; Paul Greengard
Purification and characterization of Ca2+/calmodulin-dependent protein kinase I from bovine brain.
The Journal of biological chemistry 1987;262(15):7273-81.
1987: C Hammond; D Paupardin-Tritsch; Angus Nairn; Paul Greengard; H M Gerschenfeld
Cholecystokinin induces a decrease in Ca2+ current in snail neurons that appears to be mediated by protein kinase C.
Nature 1987;325(6107):809-11.
1986: D Paupardin-Tritsch; C Hammond; H M Gerschenfeld; Angus Nairn; Paul Greengard
cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones.
Nature 1986;323(6091):812-4.
1986: Charles D Woody; T Bartfai; E Gruen; Angus Nairn
Intracellular injection of cGMP-dependent protein kinase results in increased input resistance in neurons of the mammalian motor cortex.
Brain research 1986;386(1-2):379-85.
1986: Ken Mackie; Y Lai; Angus Nairn; Paul Greengard; Bruce R Pitt; John Lazo
Protein phosphorylation in cultured endothelial cells.
Journal of cellular physiology 1986;128(3):367-74.
1986: Y Lai; Angus Nairn; Paul Greengard
Autophosphorylation reversibly regulates the Ca2+/calmodulin-dependence of Ca2+/calmodulin-dependent protein kinase II.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(12):4253-7.
1986: J C Saez; david spray; Angus Nairn; E Hertzberg; Paul Greengard; Michael V L Bennett
cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2473-7.
1986: S I Walaas; Angus Nairn; Paul Greengard
PCPP-260, a Purkinje cell-specific cyclic AMP-regulated membrane phosphoprotein of Mr 260,000.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(4):954-61.
1986: H C Hemmings; Angus Nairn; Paul Greengard
Protein kinases and phosphoproteins in the nervous system.
Research publications - Association for Research in Nervous and Mental Disease 1986;64():47-69.
1985: Angus Nairn; B Bhagat; H C Palfrey
Identification of calmodulin-dependent protein kinase III and its major Mr 100,000 substrate in mammalian tissues.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(23):7939-43.
1985: Angus Nairn; H C Hemmings; Paul Greengard
Protein kinases in the brain.
Annual review of biochemistry 1985;54():931-76.
1984: H C Hemmings; Angus Nairn; Paul Greengard
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.
The Journal of biological chemistry 1984;259(23):14491-7.
1984: K A Albert; E Helmer-Matyjek; Angus Nairn; T H Müller; J W Haycock; L A Greene; M Goldstein; Paul Greengard
Calcium/phospholipid-dependent protein kinase (protein kinase C) phosphorylates and activates tyrosine hydroxylase.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(24):7713-7.
1984: J A Detre; Angus Nairn; D W Aswad; Paul Greengard
Localization in mammalian brain of G-substrate, a specific substrate for guanosine 3',5'-cyclic monophosphate-dependent protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(11):2843-9.
1984: M M King; C Y Huang; P B Chock; Angus Nairn; H C Hemmings; K F Chan; Paul Greengard
Mammalian brain phosphoproteins as substrates for calcineurin.
The Journal of biological chemistry 1984;259(13):8080-3.
1984: K A Albert; W C Wu; Angus Nairn; Paul Greengard
Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(12):3622-5.
1984: Angus Nairn; R J Grand; S V Perry
The amino acid sequence of rabbit skeletal muscle calmodulin.
FEBS letters 1984;167(2):215-20.
1984: H C Hemmings; Angus Nairn; D W Aswad; Paul Greengard
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1984;4(1):99-110.
1983: Angus Nairn; Paul Greengard
Cyclic GMP-dependent protein phosphorylation in mammalian brain.
Federation proceedings 1983;42(14):3107-13.
1983: S I Walaas; Angus Nairn; Paul Greengard
Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. II. Soluble systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(2):302-11.
1983: S I Walaas; Angus Nairn; Paul Greengard
Regional distribution of calcium- and cyclic adenosine 3':5'-monophosphate-regulated protein phosphorylation systems in mammalian brain. I. Particulate systems.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(2):291-301.
1983: A C Dolphin; J A Detre; D J Schlichter; Angus Nairn; H H Yeh; D J Woodward; Paul Greengard
Cyclic nucleotide-dependent protein kinases and some major substrates in the rat cerebellum after neonatal X-irradiation.
Journal of neurochemistry 1983;40(2):577-81.
1982: V F Castellucci; Angus Nairn; Paul Greengard; J H Schwartz; Eric R Kandel
Inhibitor of adenosine 3':5'-monophosphate-dependent protein kinase blocks presynaptic facilitation in Aplysia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(12):1673-81.
1982: Angus Nairn; J A Detre; J E Casnellie; Paul Greengard
Serum antibodies that distinguish between the phospho- and dephospho-forms of a phosphoprotein.
Nature 1982;299(5885):734-6.
1982: W C Wu; S I Walaas; Angus Nairn; Paul Greengard
Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomes.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(17):5249-53.
1980: L K Kaczmarek; K R Jennings; F Strumwasser; Angus Nairn; U Walter; F D Wilson; Paul Greengard
Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell culture.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7487-91.
1980: V F Castellucci; Eric R Kandel; J H Schwartz; F D Wilson; Angus Nairn; Paul Greengard
Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7492-6.
1980: R J Grand; Angus Nairn; S V Perry
The preparation of calmodulins from barley (Hordeum sp.) and basidiomycete fungi.
The Biochemical journal 1980;185(3):755-60.
1980: Angus Nairn; R J Grand; C M Wall; S V Perry
The relationship of the structure to the function of calmodulin in the myosin light chain kinase system.
Annals of the New York Academy of Sciences 1980;356():413-4.
1979: Shirish Shenolikar; P T Cohen; P Cohen; Angus Nairn; S V Perry
The role of calmodulin in the structure and regulation of phosphorylase kinase from rabbit skeletal muscle.
European journal of biochemistry / FEBS 1979;100(2):329-37.
1979: Angus Nairn; S V Perry
The role of calmodulin in the myosin light-chain kinase system [proceedings].
Biochemical Society transactions 1979;7(5):966-7.
1979: S V Perry; R J Grand; Angus Nairn; T C Vanaman; C M Wall
Calcium-binding proteins and the regulation of contractile activity.
Biochemical Society transactions 1979;7(4):619-22.
1979: Angus Nairn; S V Perry
Calmodulin and myosin light-chain kinase of rabbit fast skeletal muscle.
The Biochemical journal 1979;179(1):89-97.
1977: D K Apps; Angus Nairn
The equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver.
The Biochemical journal 1977;167(1):87-93.