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Valery Krasnoperov

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Tumor Cell Line

Physiology

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Publications

TOP 3
Dan Li; Zibo Li; Ren Liu; Shuanglong Liu; Ryan Park; Hong Shan; Parkash S Gill; Lindsey Hughes; Valery Krasnoperov; Peter S Conti
Targeting the EphB4 receptor for cancer diagnosis and therapy monitoring.
Ren Liu; Kranthi Naga; Zhanfeng Sun; Alexandre Trindade; Fred A Weaver; Antonio Duarte; Valery Krasnoperov; Ram Kumar; Parkash S Gill
Inhibition of Notch signaling by Dll4-Fc promotes reperfusion of acutely ischemic tissues.
Alexandre Trindade; Marina Badenes; Dusan Djokovic; Ana-Carina Fernandes; Joana Gigante; Parkash S Gill; Valery Krasnoperov; Ren Liu; Luís Lopes-da-Costa; Ana-Rita Pedrosa; António Duarte
Low-dosage inhibition of Dll4 signaling promotes wound healing by inducing functional neo-angiogenesis.

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All Publications

2013: Dan Li; Zibo Li; Ren Liu; Shuanglong Liu; Ryan Park; Hong Shan; Parkash S Gill; Lindsey Hughes; Valery Krasnoperov; Peter S Conti
Targeting the EphB4 receptor for cancer diagnosis and therapy monitoring.
Molecular pharmaceutics 2013;10(1):329-36.
2012: Ren Liu; Kranthi Naga; Zhanfeng Sun; Alexandre Trindade; Fred A Weaver; Antonio Duarte; Valery Krasnoperov; Ram Kumar; Parkash S Gill
Inhibition of Notch signaling by Dll4-Fc promotes reperfusion of acutely ischemic tissues.
Biochemical and biophysical research communications 2012;418(1):173-9.
2012: Alexandre Trindade; Marina Badenes; Dusan Djokovic; Ana-Carina Fernandes; Joana Gigante; Parkash S Gill; Valery Krasnoperov; Ren Liu; Luís Lopes-da-Costa; Ana-Rita Pedrosa; António Duarte
Low-dosage inhibition of Dll4 signaling promotes wound healing by inducing functional neo-angiogenesis.
PloS one 2012;7(1):e29863.
2010: Whitney A Spannuth; Lingegowda S Mangala; Rebecca L Stone; Amy R Carroll; Masato Nishimura; Mian Shahzad; Sun-Joo Lee; Myrthala Moreno-Smith; Alpa M Nick; Ren Liu; Nicholas B Jennings; Yvonne G Lin; William M Merritt; Robert L Coleman; Pablo E Vivas-Mejia; Yue Zhou; Valery Krasnoperov; Gabriel Lopez-Berestein; parkash Gill; Anil K Sood
Converging evidence for efficacy from parallel EphB4-targeted approaches in ovarian carcinoma.
Molecular cancer therapeutics 2010;9(8):2377-88.
2010: Valery Krasnoperov; S Ram Kumar; Eric J Ley; Xiuqing Li; Jeffrey Scehnet; Ren Liu; Sergey Zozulya; parkash Gill
Novel EphB4 monoclonal antibodies modulate angiogenesis and inhibit tumor growth.
The American journal of pathology 2010;176(4):2029-38.
2010: Dusan Djokovic; Alexandre Trindade; Joana Gigante; Marina Badenes; Lilliana Silva; Ren Liu; Xiuqing Li; Ming Gong; Valery Krasnoperov; parkash Gill; Antonio Duarte
Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis.
BMC cancer 2010;10():641.
2010: T J Martin; E H Allan; P W M Ho; J H Gooi; J M W Quinn; M T Gillespie; Valery Krasnoperov; Natalie Sims
Communication between ephrinB2 and EphB4 within the osteoblast lineage.
Advances in experimental medicine and biology 2010;658():51-60.
2010: Shikun He; S Ram Kumar; Peng Zhou; Valery Krasnoperov; Stephen J Ryan; parkash Gill; David R Hinton
Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro.
Investigative ophthalmology & visual science 2010;51(1):543-52.
2009: S Ram Kumar; Jeffrey S Scehnet; Eric J Ley; Jasbir Singh; Valery Krasnoperov; Ren Liu; Parmeet K Manchanda; Robert D Ladner; Debra Hawes; Fred A Weaver; Robert W Beart; Gagandeep Singh; Cu Nguyen; Michael Kahn; parkash Gill
Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.
Cancer research 2009;69(9):3736-45.
2009: Valery Krasnoperov; Igor E Deyev; Oxana V Serova; Chongfeng Xu; Yun Lu; Leonid Buryanovsky; Alexander G Gabibov; Thomas A Neubert; Alexander G Petrenko
Dissociation of the subunits of the calcium-independent receptor of alpha-latrotoxin as a result of two-step proteolysis.
Biochemistry 2009;48(14):3230-8.
2009: Jeffrey Scehnet; Eric J Ley; Valery Krasnoperov; Ren Liu; Parmeet K Manchanda; Eric Sjoberg; Anna P Kostecke; Sachin Gupta; S Ram Kumar; parkash Gill
The role of Ephs, Ephrins, and growth factors in Kaposi sarcoma and implications of EphrinB2 blockade.
Blood 2009;113(1):254-63.
2007: Kimberly A Bishop; Tzanko S Stantchev; Andrew C Hickey; Dimple Khetawat; Katharine N Bossart; Valery Krasnoperov; Parkash Gill; Yan-Ru Feng; Lemin Wang; Bryan T Eaton; Lin-Fa Wang; Christopher C Broder
Identification of Hendra virus G glycoprotein residues that are critical for receptor binding.
Journal of virology 2007;81(11):5893-901.
2007: Jeffrey Scehnet; Weidong Jiang; S Ram Kumar; Valery Krasnoperov; Alexandre Trindade; Rui Benedito; Dusan Djokovic; Cristina Borges; Eric J Ley; António Duarte; parkash Gill
Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion.
Blood 2007;109(11):4753-60.
2007: S Ram Kumar; Rizwan Masood; Whitney A Spannuth; Jasbir Singh; Jeffrey Scehnet; G Kleiber; Nicholas B Jennings; M Deavers; Valery Krasnoperov; Louis Dubeau; Fred A Weaver; Anil K Sood; parkash Gill
The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome.
British journal of cancer 2007;96(7):1083-91.
2007: Melissa M Damschroder; Lusiana Widjaja; parkash Gill; Valery Krasnoperov; Weidong Jiang; William F Dall'Acqua; Herren Wu
Framework shuffling of antibodies to reduce immunogenicity and manipulate functional and biophysical properties.
Molecular immunology 2007;44(11):3049-60.
2006: Rizwan Masood; S Ram Kumar; Uttam K Sinha; David L Crowe; Valery Krasnoperov; Ramachandra K Reddy; Sergey Zozulya; Jasbir Singh; Guangbin Xia; Daniel Broek; Axel H Schönthal; parkash Gill
EphB4 provides survival advantage to squamous cell carcinoma of the head and neck.
International journal of cancer. Journal international du cancer 2006;119(6):1236-48.
2006: S Ram Kumar; Jasbir Singh; Guangbin Xia; Valery Krasnoperov; Loubna Hassanieh; Eric J Ley; Jeffrey Scehnet; Neil G Kumar; Debra Hawes; Michael F Press; Fred A Weaver; parkash Gill
Receptor tyrosine kinase EphB4 is a survival factor in breast cancer.
The American journal of pathology 2006;169(1):279-93.
2006: Nathalie Kertesz; Valery Krasnoperov; Ramachandra Reddy; Lucy Leshanski; S Ram Kumar; Sergey Zozulya; parkash Gill
The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth.
Blood 2006;107(6):2330-8.
2006: Guangbin Xia; S Ram Kumar; John P Stein; Jasbir Singh; Valery Krasnoperov; Sutao Zhu; Loubna Hassanieh; D L Smith; M Buscarini; Daniel Broek; David I Quinn; Fred A Weaver; parkash Gill
EphB4 receptor tyrosine kinase is expressed in bladder cancer and provides signals for cell survival.
Oncogene 2006;25(5):769-80.
2005: Shikun He; Yi Ding; Jiehao Zhou; Valery Krasnoperov; Sergey Zozulya; S Ram Kumar; Stephen J Ryan; parkash Gill; David R Hinton
Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization.
Investigative ophthalmology & visual science 2005;46(12):4772-9.
2005: Guangbin Xia; S Ram Kumar; Rizwan Masood; Michael Koss; Claire Templeman; David Quinn; Sutao Zhu; Ramachandra Reddy; Valery Krasnoperov; parkash Gill
Up-regulation of EphB4 in mesothelioma and its biological significance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(12):4305-15.
2005: Guangbin Xia; S Ram Kumar; Rizwan Masood; Sutao Zhu; Ramchandra Reddy; Valery Krasnoperov; David I Quinn; Susan M Henshall; Robert L Sutherland; Jacek Pinski; Siamak Daneshmand; M Buscarini; John P Stein; Chen Zhong; Daniel Broek; Pradip Roy-Burman; parkash Gill
EphB4 expression and biological significance in prostate cancer.
Cancer research 2005;65(11):4623-32.
2002: Valery Krasnoperov; Yun Lu; Leonid Buryanovsky; Thomas A Neubert; Konstantin Ichtchenko; Alexander G Petrenko
Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif.
The Journal of biological chemistry 2002;277(48):46518-26.
2002: Valery Krasnoperov; Mary A Bittner; Wenjun Mo; Leonid Buryanovsky; Thomas A Neubert; Ronald W Holz; Konstantin Ichtchenko; Alexander G Petrenko
Protein-tyrosine phosphatase-sigma is a novel member of the functional family of alpha-latrotoxin receptors.
The Journal of biological chemistry 2002;277(39):35887-95.
2000: Michael Hlubek; Edward L Stuenkel; Valery Krasnoperov; Alexander G Petrenko; Ronald W Holz
Calcium-independent receptor for alpha-latrotoxin and neurexin 1alpha [corrected] facilitate toxin-induced channel formation: evidence that channel formation results from tethering of toxin to membrane.
Molecular pharmacology 2000;57(3):519-28.
1999: Konstantin Ichtchenko; Mary A Bittner; Valery Krasnoperov; Roger Little; Oleg G Chepurny; Ronald W Holz; Alexander G Petrenko
A novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptors.
The Journal of biological chemistry 1999;274(9):5491-8.
1999: Valery Krasnoperov; Mary A Bittner; Ronald W Holz; Oleg G Chepurny; Alexander G Petrenko
Structural requirements for alpha-latrotoxin binding and alpha-latrotoxin-stimulated secretion. A study with calcium-independent receptor of alpha-latrotoxin (CIRL) deletion mutants.
The Journal of biological chemistry 1999;274(6):3590-6.
1999: K E Volynskiĭ; Tatyana M Volkova; TG Galkina; Valery Krasnoperov; Kirill A Pluzhnikov; M V Khvoshchev; Eugene V Grishin
[Molecular cloning and primary structure of cDNA fragment for alpha-latrocrustatoxin from black widow spider venom].
Bioorganicheskaia khimiia 1999;25(1):25-30.
1998: Mary A Bittner; Valery Krasnoperov; Edward L Stuenkel; Alexander G Petrenko; Ronald W Holz
A Ca2+-independent receptor for alpha-latrotoxin, CIRL, mediates effects on secretion via multiple mechanisms.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(8):2914-22.
1998: Martin Geppert; Mikhail Khvotchev; Valery Krasnoperov; Y Goda; Markus Missler; Robert E Hammer; Konstantin Ichtchenko; Alexander G Petrenko; Thomas C Südhof
Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action.
The Journal of biological chemistry 1998;273(3):1705-10.
1997: Valery Krasnoperov; Mary A Bittner; Ronald C Beavis; Y Kuang; Konstantin Salnikow; Oleg G Chepurny; Roger Little; A N Plotnikov; D Wu; Ronald W Holz; Alexander G Petrenko
alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor.
Neuron 1997;18(6):925-37.
1996: Valery Krasnoperov; Ronald C Beavis; Oleg G Chepurny; Roger Little; A N Plotnikov; Alexander G Petrenko
The calcium-independent receptor of alpha-latrotoxin is not a neurexin.
Biochemical and biophysical research communications 1996;227(3):868-75.
1996: Alexander G Petrenko; B Ullrich; Markus Missler; Valery Krasnoperov; T W Rosahl; Thomas C Südhof
Structure and evolution of neurexophilin.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(14):4360-9.
1996: I E Dulubova; Valery Krasnoperov; M V Khvotchev; Kirill A Pluzhnikov; Tatyana M Volkova; E V Grishin; H Vais; D R Bell; Peter N R Usherwood
Cloning and structure of delta-latroinsectotoxin, a novel insect-specific member of the latrotoxin family: functional expression requires C-terminal truncation.
The Journal of biological chemistry 1996;271(13):7535-43.
1996: I E Dulubova; M V Khvoshchev; Valery Krasnoperov; T G Galkina; Kirill A Pluzhnikov; Tatyana M Volkova; E V Grishin
[Primary structure of delta-latroinsectotoxin from venom of the Latrodectus mactans tredecimguttatus spider].
Bioorganicheskaia khimiia 1996;22(1):68-73.
1995: Bazbek Davletov; Valery Krasnoperov; Y Hata; Alexander G Petrenko; Thomas C Südhof
High affinity binding of alpha-latrotoxin to recombinant neurexin I alpha.
The Journal of biological chemistry 1995;270(41):23903-5.
1991: Valery Krasnoperov; O G Shamotienko; E V Grishin
[Interaction of alpha-(125)latrocrustotoxin with nerve cell membranes from the river crab Astacus astacus].
Bioorganicheskaia khimiia 1991;17(5):716-8.
1990: Valery Krasnoperov; O G Shamotienko; E V Grishin
[A crustacean-specific neurotoxin from the venom of the black widow spider Latrodectus mactans tredecimguttatus].
Bioorganicheskaia khimiia 1990;16(11):1567-9.
1990: Valery Krasnoperov; O G Shamotienko; E V Grishin
[Isolation and properties of insect-specific neurotoxins from venoms of the spider Lactodectus mactans tredecimguttatus].
Bioorganicheskaia khimiia 1990;16(8):1138-40.
1990: Alexander G Petrenko; I N Surkova; O G Shamotienko; V A Kovalenko; Valery Krasnoperov; L A Tret'iakov; Iu A Ushkarev; E V Grishin
[Study of the receptor for black widow spider neurotoxin. II. Isolation and characteristics of the receptor from bovine brain membranes].
Bioorganicheskaia khimiia 1990;16(2):158-65.
1989: V N Pashkov; G I Kovalevskaia; Valery Krasnoperov; O V Bulgakov
[Isolation of alpha-latrotoxin from karakurt spider venom using monoclonal antibodies].
Bioorganicheskaia khimiia 1989;15(9):1281-3.