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Sherven Sharma

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Sherven Sharma; Maie St John; Li Zhu; Michael Davoodi; Marni Harris-White; Jay M Lee; Ravi Salgia; Steven Dubinett
TLR3 agonists and proinflammatory antitumor activities.
Sherven Sharma; Steven Dubinett; Ravi Salgia
CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer.
Miranda Dennis; Mariam Dohadwala; Steven M Dubinett; David A Elashoff; Yuan Lin; Jie Luo; Sherven Sharma; Elliot Abemayor; Guanyu Wang; Maie A St John
Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells.

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2013: Sherven Sharma; Maie St John; Li Zhu; Michael Davoodi; Marni Harris-White; Jay M Lee; Ravi Salgia; Steven Dubinett
TLR3 agonists and proinflammatory antitumor activities.
Expert opinion on therapeutic targets 2013;17(5):481-3.
2012: Sherven Sharma; Steven Dubinett; Ravi Salgia
CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer.
American journal of respiratory and critical care medicine 2012;186(10):940-1.
2012: Miranda Dennis; Mariam Dohadwala; Steven M Dubinett; David A Elashoff; Yuan Lin; Jie Luo; Sherven Sharma; Elliot Abemayor; Guanyu Wang; Maie A St John
Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2012;147(4):726-32.
2012: Guanyu Wang; Weifang Yang; Hai Liu; Luying Liu; Sherven Sharma; Xiaonan Sun; Qinghua Dong
Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells.
Biochemical and biophysical research communications 2012;425(2):309-14.
2012: David Hu; Min Huang; Ontario D Lau; Yuan Lin; William H McBride; Dorthe Schaue; Sherven Sharma; Elliot Abemayor; Miranda Dennis; Steven M Dubinett; David A Elashoff; Guanyu Wang; Linda Wang; Ben Wu; Li Zhu; Maie A St John
A novel modular polymer platform for the treatment of head and neck squamous cell carcinoma in an animal model.
Archives of otolaryngology--head & neck surgery 2012;138(4):412-7.
2012: Minu K Srivastava; Li Zhu; Asa Andersson; Steven Dubinett; Marni Harris-White; Jay M Lee; Sherven Sharma
Myeloid suppressor cells and immune modulation in lung cancer.
Immunotherapy 2012;4(3):291-304.
2012: Guanyu Wang; Jiawei Zhang; Luying Liu; Sherven Sharma; Qinghua Dong
Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl.
PloS one 2012;7(12):e51764.
2012: Matthew Rettig; Sherven Sharma; Fuyuhiko Tamanoi; Kenny Trinidad; Patrick Frost; Farhad Moatamed; G Pezeshkpour; Fariborz Mortazavi
PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells.
PloS one 2012;7(7):e42012.
2012: Minu K Srivastava; Robert Strieter; Li Zhu; Upendra K Kar; Steven M Dubinett; David Elashoff; Marni Harris-White; Min Huang; Ming F Johnson; Upendra Kar; Jay M Lee; Sherven Sharma
Myeloid suppressor cell depletion augments antitumor activity in lung cancer.
PloS one 2012;7(7):e40677.
2012: Upendra K Kar; Cheryl I Champion; Janina Jiang; Valerie A Kickhoefer; Kayvan R Niazi; Shahrooz Rabizadeh; Leonard H Rome; Sahar Salehi; Sherven Sharma; Minu Srivastava; Kathleen A Kelly
Vault nanocapsules as adjuvants favor cell-mediated over antibody-mediated immune responses following immunization of mice.
PloS one 2012;7(7):e38553.
2011: Sherven Sharma; Minu K Srivastava; Marni Harris-White; Jay Moon Lee; Steven Dubinett
MUC1 peptide vaccine mediated antitumor activity in non-small cell lung cancer.
Expert opinion on biological therapy 2011;11(8):987-90.
2011: Asa Andersson; Minu K Srivastava; Marni Harris-White; Min Huang; Li Zhu; David Elashoff; Robert M Strieter; Steven M Dubinett; Sherven Sharma
Role of CXCR3 ligands in IL-7/IL-7R alpha-Fc-mediated antitumor activity in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(11):3660-72.
2011: Upendra K Kar; Minu K Srivastava; Asa Andersson; Felicita Baratelli; Min Huang; Valerie A Kickhoefer; Steven M Dubinett; Leonard H Rome; Sherven Sharma
Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth.
PloS one 2011;6(5):e18758.
2010: Steven M Dubinett; Jay M Lee; Sherven Sharma; James J Mulé
Chemokines: can effector cells be redirected to the site of the tumor?
Cancer journal (Sudbury, Mass.) 2010;16(4):325-35.
2010: Ines Herrmann; Patrick A Baeuerle; Matthias Friedrich; Alexander Murr; Susanne Filusch; Dominik Rüttinger; Mariam W Majdoub; Sherven Sharma; Peter Kufer; Tobias Raum; Markus Münz
Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells.
PloS one 2010;5(10):e13474.
2010: Felicita Baratelli; Jay M Lee; Saswati Hazra; Ying Lin; Tonya C Walser; Dorthe Schaue; Peter S Pak; David Elashoff; Karen Reckamp; Ling Zhang; Michael C Fishbein; Sherven Sharma; Steven M Dubinett
PGE(2) contributes to TGF-beta induced T regulatory cell function in human non-small cell lung cancer.
American journal of translational research 2010;2(4):356-67.
2009: Jane Yanagawa; Tonya C Walser; Li X Zhu; Longsheng Hong; Michael C Fishbein; Vei Mah; David Chia; Lee Goodglick; David Elashoff; Jie Luo; Clara E Magyar; Mariam Dohadwala; Jay M Lee; Maie A St John; Robert M Strieter; Sherven Sharma; Steven M Dubinett
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(22):6820-9.
2009: Maie A R St John; Mariam Dohadwala; Jie Luo; Guanyu Wang; Gina Lee; Hubert Shih; Eileen Heinrich; Kostyantyn Krysan; Tonya Walser; Saswati Hazra; Li Zhu; Chi Lai; Elliot Abemayor; Michael Fishbein; David Elashoff; Sherven Sharma; Steven M Dubinett
Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6018-27.
2009: Steven Dubinett; Sherven Sharma
Towards effective immunotherapy for lung cancer: simultaneous targeting of tumor-initiating cells and immune pathways in the tumor microenvironment.
Immunotherapy 2009;1(5):721-5.
2009: Mysore S Veena; Min Qin; Asa Andersson; Sherven Sharma; Raj K Batra
CAR mediates efficient tumor engraftment of mesenchymal type lung cancer cells.
Laboratory investigation; a journal of technical methods and pathology 2009;89(8):875-86.
2009: Sherven Sharma; Y Zhuang; Zhe Ying; A Wu; Fernando Gomez-Pinilla
Dietary curcumin supplementation counteracts reduction in levels of molecules involved in energy homeostasis after brain trauma.
Neuroscience 2009;161(4):1037-44.
2009: Sherven Sharma; Asa Andersson
Adenovirus E3 proteins help tumors to evade innate and adaptive immune responses.
Cancer biology & therapy 2009;8(12):1133-5.
2009: Asa Andersson; Seok-Chul Yang; Min Huang; Li Zhu; Upendra Kar; Raj K Batra; David Elashoff; Robert M Strieter; Steven M Dubinett; Sherven Sharma
IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):6951-8.
2009: Saroj K Basak; Mysore S Veena; Scott Oh; Ge Huang; Eri Srivatsan; Min Huang; Sherven Sharma; Raj K Batra
The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer.
PloS one 2009;4(6):e5884.
2008: Tonya Walser; Xiaoyan Cui; Jane Yanagawa; Jay M Lee; Eileen Heinrich; Gina Lee; Sherven Sharma; Steven M Dubinett
Smoking and lung cancer: the role of inflammation.
Proceedings of the American Thoracic Society 2008;5(8):811-5.
2008: Jay M Lee; Jane Yanagawa; Katherine A Peebles; Sherven Sharma; Jenny T Mao; Steven M Dubinett
Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment.
Critical reviews in oncology/hematology 2008;66(3):208-17.
2008: Karen Reckamp; Brian Gardner; Robert A Figlin; David Elashoff; Kostyantyn Krysan; Mariam Dohadwala; Jenny Mao; Sherven Sharma; Landon Inge; Ayyappan Rajasekaran; Steven M Dubinett
Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(2):117-24.
2008: Kostyantyn Krysan; Jay M Lee; Mariam Dohadwala; Brian Gardner; Karen Reckamp; Edward Garon; Maie St John; Sherven Sharma; Steven M Dubinett
Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(2):107-10.
2008: Saswati Hazra; Katherine A Peebles; Sherven Sharma; Jenny T Mao; Steven M Dubinett
The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer.
PPAR research 2008;2008():790568.
2008: Felicita Baratelli; Hiroko Takedatsu; Saswati Hazra; Katherine Peebles; Jie Luo; Pam S Kurimoto; Gang Zeng; Raj K Batra; Sherven Sharma; Steven M Dubinett; Jay M Lee
Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer.
Journal of translational medicine 2008;6():38.
2007: Ming Liu; Seok-Chul Yang; Sherven Sharma; Jie Luo; Xiaoyan Cui; Katherine A Peebles; Min Huang; Mitsuo Sato; Ruben D Ramirez; Jerry W Shay; John D Minna; Steven M Dubinett
EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2007;37(5):578-88.
2007: Katherine A Peebles; Jay M Lee; Jenny T Mao; Saswati Hazra; Karen Reckamp; Kostyantyn Krysan; Mariam Dohadwala; Eileen L Heinrich; Tonya C Walser; Xiaoyan Cui; Felicita Baratelli; Edward Garon; Sherven Sharma; Steven M Dubinett
Inflammation and lung carcinogenesis: applying findings in prevention and treatment.
Expert review of anticancer therapy 2007;7(10):1405-21.
2007: Saswati Hazra; Raj K Batra; Hsin H Tai; Sherven Sharma; Xiaoyan Cui; Steven M Dubinett
Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase.
Molecular pharmacology 2007;71(6):1715-20.
2006: Bao Hoang; Li Zhu; Yijiang Shi; Patrick Frost; Huajun Yan; Sanjai Sharma; Sherven Sharma; Lee Goodglick; Steven M Dubinett; Alan Lichtenstein
Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance.
Blood 2006;107(11):4484-90.
2006: Xiaoyan Cui; Seok-Chul Yang; Sherven Sharma; Nathalie Heuze-Vourc'h; Steven M Dubinett
IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer.
Biochemical and biophysical research communications 2006;343(4):995-1001.
2006: Mariam Dohadwala; Seok-Chul Yang; Jie Luo; Sherven Sharma; Raj K Batra; Min Huang; Ying Lin; Lee Goodglick; Kostyantyn Krysan; Michael C Fishbein; Longsheng Hong; Chi Lai; Robert B Cameron; Robert M Gemmill; Harry A Drabkin; Steven M Dubinett
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer.
Cancer research 2006;66(10):5338-45.
2006: Kostyantyn Krysan; Karen Reckamp; Sherven Sharma; Steven M Dubinett
The potential and rationale for COX-2 inhibitors in lung cancer.
Anti-cancer agents in medicinal chemistry 2006;6(3):209-20.
2006: Sven Hillinger; S-C Yang; Raj K Batra; R M Strieter; Walter Weder; S M Dubinett; Sherven Sharma
CCL19 reduces tumour burden in a model of advanced lung cancer.
British journal of cancer 2006;94(7):1029-34.
2006: Seok-Chul Yang; Raj K Batra; Sven Hillinger; Karen Reckamp; Robert M Strieter; Steven M Dubinett; Sherven Sharma
Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Cancer research 2006;66(6):3205-13.
2006: Judong Pan; Marie D Burdick; John A Belperio; Ying Ying Xue; Craig Gerard; Sherven Sharma; Steven M Dubinett; Robert M Strieter
CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(3):1456-64.
2006: Ling Zhang; Sherven Sharma; Jerome M Hershman; Gregory A Brent; Steven M Dubinett; Min Huang
Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation.
Cancer gene therapy 2006;13(1):74-81.
2005: Harnisha Dalwadi; Kostyantyn Krysan; Nathalie Heuze-Vourc'h; Mariam Dohadwala; David Elashoff; Sherven Sharma; Nicholas Cacalano; Alan Lichtenstein; Steven M Dubinett
Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7674-82.
2005: Felicita Baratelli; Ying Lin; Li Zhu; Seok-Chul Yang; Nathalie Heuzé-Vourc'h; Gang Zeng; Karen Reckamp; Mariam Dohadwala; Sherven Sharma; Steven M Dubinett
Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1483-90.
2005: Felicita Baratelli; Kostyantyn Krysan; Nathalie Heuzé-Vourc'h; Li Zhu; Brian Escuadro; Sherven Sharma; Karen Reckamp; Mariam Dohadwala; Steven M Dubinett
PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells.
Journal of leukocyte biology 2005;78(2):555-64.
2005: Nathalie Heuzé-Vourc'h; Ming Liu; Harnisha Dalwadi; Felicita Baratelli; Li Zhu; Lee Goodglick; Mehis Põld; Sherven Sharma; Ruben D Ramirez; Jerry W Shay; John D Minna; Robert M Strieter; Steven M Dubinett
IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression.
Biochemical and biophysical research communications 2005;333(2):470-5.
2005: Kostyantyn Krysan; Karen Reckamp; Harnisha Dalwadi; Sherven Sharma; Enrique Rozengurt; Mariam Dohadwala; Steven M Dubinett
Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner.
Cancer research 2005;65(14):6275-81.
2005: Sherven Sharma; Li Zhu; Seok-Chul Yang; Ling Zhang; Jeff Lin; Sven Hillinger; Brian Gardner; Karen Reckamp; Robert M Strieter; Min Huang; Raj K Batra; Steven M Dubinett
Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):813-9.
2005: Jenny T Mao; Xiaoyan Cui; Karen Reckamp; Ming Liu; Kostyantyn Krysan; Harnisha Dalwadi; Sherven Sharma; Saswati Hazra; Robert M Strieter; Brian Gardner; Steven M Dubinett
Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer.
Clinical lung cancer 2005;7(1):30-9.
2005: Sherven Sharma; Seok-Chul Yang; Li Zhu; Karen Reckamp; Brian Gardner; Felicita Baratelli; Min Huang; Raj K Batra; Steven M Dubinett
Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer.
Cancer research 2005;65(12):5211-20.
2005: Min Qin; Brian Escuadro; Sherven Sharma; Raj K Batra
Gene transfer mediated by native versus fibroblast growth factor-retargeted adenoviral vectors into lung cancer cells.
American journal of respiratory cell and molecular biology 2005;32(3):211-7.
2005: Seth C Gamradt; Brian T Feeley; Nancy Q Liu; Jason Roostaeian; Ying Q Lin; Li X Zhu; Sherven Sharma; Steven M Dubinett; Jay R Lieberman
The effect of cyclooxygenase-2 (COX-2) inhibition on human prostate cancer induced osteoblastic and osteolytic lesions in bone.
Anticancer research 2005;25(1A):107-15.
2004: Robert M Strieter; John A Belperio; Marie D Burdick; Sherven Sharma; Steven M Dubinett; Michael P Keane
CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer.
Annals of the New York Academy of Sciences 2004;1028():351-60.
2004: Felicita Baratelli; Nathalie Heuzé-Vourc'h; Kostyantyn Krysan; Mariam Dohadwala; Karen Riedl; Sherven Sharma; Steven M Dubinett
Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5458-66.
2004: Mehis Põld; Kostyantyn Krysan; Anu Põld; Mariam Dohadwala; Nathalie Heuze-Vourc'h; Jenny T Mao; Karen L Riedl; Sherven Sharma; Steven M Dubinett
Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer.
Cancer research 2004;64(18):6549-55.
2004: Min Qin; Brian Escuadro; Mariam Dohadwala; Sherven Sharma; Raj K Batra
A novel role for the coxsackie adenovirus receptor in mediating tumor formation by lung cancer cells.
Cancer research 2004;64(18):6377-80.
2004: Kostyantyn Krysan; Harnisha Dalwadi; Sherven Sharma; Mehis Põld; Steven M Dubinett
Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer.
Cancer research 2004;64(18):6359-62.
2004: Ling Zhang; Michael P Keane; Li X Zhu; Sherven Sharma; Enrique Rozengurt; Robert M Strieter; Steven M Dubinett; Min Huang
Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis.
The Journal of biological chemistry 2004;279(27):28315-9.
2004: Karen Riedl; Kostyantyn Krysan; Mehis Põld; Harnisha Dalwadi; Nathalie Heuze-Vourc'h; Mariam Dohadwala; Ming Liu; Xiaoyan Cui; Robert Figlin; Jenny T Mao; Robert M Strieter; Sherven Sharma; Steven M Dubinett
Multifaceted roles of cyclooxygenase-2 in lung cancer.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2004;7(3):169-84.
2004: Kostyantyn Krysan; Mariam Dohadwala; Jie Luo; Ying Lin; Li Zhu; Nathalie Heuze-Vourc'h; Lee Goodglick; Farrukh Merchant; David Seligson; Mehis Pold; Robert M Strieter; Sherven Sharma; Steven M Dubinett
Cyclooxygenase-2-dependent expression of survivin in non-small cell lung cancer.
Chest 2004;125(5 Suppl):140S.
2004: Seok-Chul Yang; Sven Hillinger; Karen Riedl; Ling Zhang; Li Zhu; Min Huang; Kimberly Atianzar; Brian Y Kuo; Brian Gardner; Raj K Batra; Robert M Strieter; Steven M Dubinett; Sherven Sharma
Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2891-901.
2004: Mehis Põld; Li X Zhu; Sherven Sharma; Marie D Burdick; Ying Lin; Peter P N Lee; Anu Põld; Jie Luo; Kostyantyn Krysan; Mariam Dohadwala; Jenny T Mao; Raj K Batra; Robert M Strieter; Steven M Dubinett
Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer.
Cancer research 2004;64(5):1853-60.
2004: Brian Gardner; Li X Zhu; Michael D Roth; Donald P Tashkin; Steven M Dubinett; Sherven Sharma
Cocaine modulates cytokine and enhances tumor growth through sigma receptors.
Journal of neuroimmunology 2004;147(1-2):95-8.
2004: Kostyantyn Krysan; Farrukh H Merchant; Li Zhu; Mariam Dohadwala; Jie Luo; Ying Lin; Nathalie Heuze-Vourc'h; Mehis Põld; David Seligson; David Chia; Lee Goodglick; Hejing Wang; Robert M Strieter; Sherven Sharma; Steven M Dubinett
COX-2-dependent stabilization of survivin in non-small cell lung cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):206-8.
2003: Sven Hillinger; Seok-Chul Yang; Li Zhu; Min Huang; Russell Duckett; Kimberly Atianzar; Raj K Batra; Robert M Strieter; Steven M Dubinett; Sherven Sharma
EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6457-65.
2003: Karen Riedl; Felicita Baratelli; Raj K Batra; Seok-Chul Yang; Jie Luo; Brian Escuadro; Robert Figlin; Robert M Strieter; Sherven Sharma; Steven M Dubinett
Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells.
Molecular cancer 2003;2():35.
2003: Sherven Sharma; Raj K Batra; Seok-Chul Yang; Sven Hillinger; Li Zhu; Kimberly Atianzar; Robert M Strieter; Karen Riedl; Min Huang; Steven M Dubinett
Interleukin-7 gene-modified dendritic cells reduce pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Human gene therapy 2003;14(16):1511-24.
2003: Brian Gardner; Li X Zhu; Sherven Sharma; Donald P Tashkin; Steven M Dubinett
Methanandamide increases COX-2 expression and tumor growth in murine lung cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(14):2157-9.
2003: Min Qin; Shuang Chen; Tina Yu; Brian Escuadro; Sherven Sharma; Raj K Batra
Coxsackievirus adenovirus receptor expression predicts the efficiency of adenoviral gene transfer into non-small cell lung cancer xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4992-9.
2003: Ling Zhang; Sherven Sharma; Li X Zhu; Takahiko Kogai; Jerome M Hershman; Gregory A Brent; Steven M Dubinett; Min Huang
Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells.
Cancer research 2003;63(16):5065-72.
2003: Sherven Sharma; Seok-Chul Yang; Sven Hillinger; Li X Zhu; Min Huang; Raj K Batra; Jeff F Lin; Marie D Burdick; Robert M Strieter; Steven M Dubinett
SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10.
Molecular cancer 2003;2():22.
2003: Li X Zhu; Sherven Sharma; Brian Gardner; Brian Escuadro; Kimberly Atianzar; Donald P Tashkin; Steven M Dubinett
IL-10 mediates sigma 1 receptor-dependent suppression of antitumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(7):3585-91.
2003: Sherven Sharma; Marina Stolina; Seok-Chul Yang; Felicita Baratelli; Jeff F Lin; Kimberly Atianzar; Jie Luo; Li Zhu; Ying Lin; Min Huang; Mariam Dohadwala; Raj K Batra; Steven M Dubinett
Tumor cyclooxygenase 2-dependent suppression of dendritic cell function.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):961-8.
2003: Nathalie Heuze-Vourc'h; Li Zhu; Kostyantyn Krysan; Raj K Batra; Sherven Sharma; Steven M Dubinett
Abnormal interleukin 10Ralpha expression contributes to the maintenance of elevated cyclooxygenase-2 in non-small cell lung cancer cells.
Cancer research 2003;63(4):766-70.
2003: Raj K Batra; Ying Lin; Sherven Sharma; Mariam Dohadwala; Jie Luo; Mehis Pold; Steven M Dubinett
Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism.
Cancer research 2003;63(3):642-6.
2003: Steven M Dubinett; Sherven Sharma; Min Huang; Mariam Dohadwala; Mehis Pold; Jenny T Mao
Cyclooxygenase-2 in lung cancer.
Progress in experimental tumor research 2003;37():138-62.
2003: Sherven Sharma; Min Huang; Mariam Dohadwala; Mehis Pold; Raj K Batra; Steven M Dubinett
Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer.
Methods in molecular medicine 2003;75():723-36.
2003: Sherven Sharma; Seok-Chul Yang; Raj K Batra; Steven M Dubinett
Intratumoral therapy with cytokine gene-modified dendritic cells in murine lung cancer models.
Methods in molecular medicine 2003;75():711-22.
2003: Raj K Batra; Raymond M Bernal; Sherven Sharma
Identifying obstacles to viral gene therapy for lung cancer. Malignant pleural effusions as a paradigm.
Methods in molecular medicine 2003;75():545-59.
2002: Mariam Dohadwala; Raj K Batra; Jie Luo; Ying Lin; Kostyantyn Krysan; Mehis Pold; Sherven Sharma; Steven M Dubinett
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
The Journal of biological chemistry 2002;277(52):50828-33.
2002: Ray M Bernal; Sherven Sharma; Brian Gardner; Joanne T Douglas; Jeffrey M Bergelson; Steven M Dubinett; Raj K Batra
Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1915-23.
2002: Saroj K Basak; Airi Harui; Marina Stolina; Sherven Sharma; Kohnosuke Mitani; Steven M Dubinett; Michael D Roth
Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage-colony-stimulating factor and interleukin-4.
Blood 2002;99(8):2869-79.
2002: Min Huang; Sherven Sharma; Li X Zhu; Michael P Keane; Jie Luo; Ling Zhang; Marie D Burdick; Ying Q Lin; Mariam Dohadwala; Brian Gardner; Raj K Batra; Robert M Strieter; Steven M Dubinett
IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis.
The Journal of clinical investigation 2002;109(7):931-7.
2002: Brian Gardner; Li X Zu; Sherven Sharma; Qian Liu; Alexandros Makriyannis; Donald P Tashkin; Steven M Dubinett
Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta.
Biochemical and biophysical research communications 2002;290(1):91-6.
2001: Sherven Sharma; Marina Stolina; Li Zhu; Ying Lin; R Batra; Min Huang; R Strieter; Steven M Dubinett
Secondary lymphoid organ chemokine reduces pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma.
Cancer research 2001;61(17):6406-12.
2001: Min Huang; Raj K Batra; Takahiko Kogai; Ying Q Lin; Jerome M Hershman; A Lichtenstein; Sherven Sharma; Li X Zhu; Gregory A Brent; Steven M Dubinett
Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer.
Cancer gene therapy 2001;8(8):612-8.
2001: Mariam Dohadwala; Jie Luo; Li Zhu; Ying Lin; Graeme Dougherty; Sherven Sharma; Min Huang; Mehis Pold; Raj K Batra; Steven M Dubinett
Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44.
The Journal of biological chemistry 2001;276(24):20809-12.
2000: Li X Zhu; Sherven Sharma; Marina Stolina; Brian Gardner; Michael D Roth; Donald P Tashkin; Steven M Dubinett
Delta-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):373-80.
2000: Raj K Batra; Steven M Dubinett; B W Henkle; Sherven Sharma; Brian Gardner
Adenoviral gene transfer is inhibited by soluble factors in malignant pleural effusions.
American journal of respiratory cell and molecular biology 2000;22(5):613-9.
2000: Steven M Dubinett; Raj K Batra; PW Miller; Sherven Sharma
Tumor antigens in thoracic malignancy.
American journal of respiratory cell and molecular biology 2000;22(5):524-7.
2000: Sherven Sharma; Marina Stolina; Jie Luo; Robert M Strieter; M Burdick; Li X Zhu; Raj K Batra; Steven M Dubinett
Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4558-63.
2000: Raj K Batra; Sherven Sharma; S M Dubinett
New gene and cell-based therapies for lung cancer.
Seminars in respiratory and critical care medicine 2000;21(5):463-72.
2000: PW Miller; Sherven Sharma; Marina Stolina; Lisa H Butterfield; J Luo; Y Lin; Mariam Dohadwala; Raj K Batra; L Wu; James S Economou; Steven M Dubinett
Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication.
Human gene therapy 2000;11(1):53-65.
2000: Marina Stolina; Sherven Sharma; Y Lin; Mariam Dohadwala; Brian Gardner; J Luo; Li Zhu; M Kronenberg; PW Miller; J Portanova; J C Lee; Steven M Dubinett
Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):361-70.
1999: Sherven Sharma; Marina Stolina; Y Lin; Brian Gardner; PW Miller; M Kronenberg; Steven M Dubinett
T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(9):5020-8.
1998: PW Miller; Sherven Sharma; Marina Stolina; K Chen; Li Zhu; R W Paul; Steven M Dubinett
Dendritic cells augment granulocyte-macrophage colony-stimulating factor (GM-CSF)/herpes simplex virus thymidine kinase-mediated gene therapy of lung cancer.
Cancer gene therapy 1998;5(6):380-9.
1998: S M Dubinett; PW Miller; Sherven Sharma; Raj K Batra
Gene therapy for lung cancer.
Hematology/oncology clinics of North America 1998;12(3):569-94.
1998: Min Huang; Marina Stolina; Sherven Sharma; Jenny T Mao; Li Zhu; PW Miller; J Wollman; harvey Herschman; Steven M Dubinett
Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production.
Cancer research 1998;58(6):1208-16.
1998: SC Schneider; H K Deng; B Rottinger; Sherven Sharma; Marina Stolina; C Bonpane; A Miller; Steven M Dubinett; B Kyewski; Eli E Sercarz
Tolerance and determinant hierarchy.
Novartis Foundation symposium 1998;215():54-66; discussion 66-72.
1997: Sherven Sharma; PW Miller; Marina Stolina; Li Zhu; Min Huang; R W Paul; Steven M Dubinett
Multicomponent gene therapy vaccines for lung cancer: effective eradication of established murine tumors in vivo with interleukin-7/herpes simplex thymidine kinase-transduced autologous tumor and ex vivo activated dendritic cells.
Gene therapy 1997;4(12):1361-70.
1997: Jenny T Mao; Li X Zhu; Sherven Sharma; K Chen; Min Huang; S J Santiago; J Gulsurd; Donald P Tashkin; Steven M Dubinett
Cocaine inhibits human endothelial cell IL-8 production: the role of transforming growth factor-beta.
Cellular immunology 1997;181(1):38-43.
1997: Amy Hagenbaugh; Sherven Sharma; S M Dubinett; S H Wei; Richard Aranda; Hilde Cheroutre; DJ Fowell; S Binder; B Tsao; Richard M Locksley; K W Moore; Mitchell Kronenberg
Altered immune responses in interleukin 10 transgenic mice.
The Journal of experimental medicine 1997;185(12):2101-10.
1996: Min Huang; Sherven Sharma; Jenny T Mao; Steven M Dubinett
Non-small cell lung cancer-derived soluble mediators and prostaglandin E2 enhance peripheral blood lymphocyte IL-10 transcription and protein production.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5512-20.
1996: Jenny T Mao; Min Huang; J Wang; Sherven Sharma; D P Tashkin; Steven M Dubinett
Cocaine down-regulates IL-2-induced peripheral blood lymphocyte IL-8 and IFN-gamma production.
Cellular immunology 1996;172(2):217-23.
1996: Sherven Sharma; J Wang; Min Huang; R W Paul; P Lee; william mcbride; James S Economou; Michael D Roth; Sylvia M Kiertscher; Steven M Dubinett
Interleukin-7 gene transfer in non-small-cell lung cancer decreases tumor proliferation, modifies cell surface molecule expression, and enhances antitumor reactivity.
Cancer gene therapy 1996;3(5):302-13.
1996: J Wang; M Huang; P Lee; Krishna Komanduri; Sherven Sharma; G Chen; Steven M Dubinett
Interleukin-8 inhibits non-small cell lung cancer proliferation: a possible role for regulation of tumor growth by autocrine and paracrine pathways.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(1):53-60.
1995: Min Huang; J Wang; P Lee; Sherven Sharma; Jenny T Mao; H Meissner; K Uyemura; R Modlin; J Wollman; Steven M Dubinett
Human non-small cell lung cancer cells express a type 2 cytokine pattern.
Cancer research 1995;55(17):3847-53.
1995: Steven M Dubinett; Min Huang; S Dhanani; James S Economou; J Wang; P Lee; Sherven Sharma; Graeme Dougherty; william mcbride
Down-regulation of murine fibrosarcoma transforming growth factor-beta 1 expression by interleukin 7.
Journal of the National Cancer Institute 1995;87(8):593-7.