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George Christ

Research Profile

Anatomy

Disorders

Physiology

Living Beings

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Genetic Therapy

Phenomena

Muscle Contraction

Chemicals & Drugs

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TOP 3
Giuseppe Orlando; Andrea Remuzzi; Jeffrey Rogers; Justin M Saul; Dror Seliktar; Keren Shapira-Schweitzer; Tom Smith; Anthony Atala; Pedro M Baptista; Kyle W Binder; Khalil N Bitar; Christopher Breuer; Luke Burnett; George Christ; Paolo De Coppi; Alan Farney; Marina Figliuzzi; James H Holmes; Kenneth Koch; Paolo Macchiarini; Sayed-Hadi Mirmalek Sani; Emmanuel Opara; Daniel Solomon; Robert J Stratta; Mark Van Dyke; Kathryn J Wood; James J Yoo; Yuanyuan Zhang; Shay Soker
Regenerative medicine as applied to general surgery.
Lucas P Neff; Bryan W Tillman; Saami K Yazdani; Masood A Machingal; James J Yoo; Shay Soker; Brian W Bernish; Randolph L Geary; George Christ
Vascular smooth muscle enhances functionality of tissue-engineered blood vessels in vivo.
George Christ
Potential applications of gene therapy/transfer to the treatment of lower urinary tract diseases/disorders.

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2012: Giuseppe Orlando; Andrea Remuzzi; Jeffrey Rogers; Justin M Saul; Dror Seliktar; Keren Shapira-Schweitzer; Tom Smith; Anthony Atala; Pedro M Baptista; Kyle W Binder; Khalil N Bitar; Christopher Breuer; Luke Burnett; George Christ; Paolo De Coppi; Alan Farney; Marina Figliuzzi; James H Holmes; Kenneth Koch; Paolo Macchiarini; Sayed-Hadi Mirmalek Sani; Emmanuel Opara; Daniel Solomon; Robert J Stratta; Mark Van Dyke; Kathryn J Wood; James J Yoo; Yuanyuan Zhang; Shay Soker
Regenerative medicine as applied to general surgery.
Annals of surgery 2012;255(5):867-80.
2011: Lucas P Neff; Bryan W Tillman; Saami K Yazdani; Masood A Machingal; James J Yoo; Shay Soker; Brian W Bernish; Randolph L Geary; George Christ
Vascular smooth muscle enhances functionality of tissue-engineered blood vessels in vivo.
Journal of vascular surgery 2011;53(2):426-34.
2011: George Christ
Potential applications of gene therapy/transfer to the treatment of lower urinary tract diseases/disorders.
Handbook of experimental pharmacology 2011;(202):255-65.
2010: Arthur L Burnett; Irwin Goldstein; Karl-Erik Andersson; Antonio Argiolas; George Christ; Kwangsung Park; Zhong C Xin
Future sexual medicine physiological treatment targets.
The journal of sexual medicine 2010;7(10):3269-304.
2010: Benjamin T Corona; Catherine L Ward; Benjamin S Harrison; George Christ
Regenerative medicine: basic concepts, current status, and future applications.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2010;58(7):849-58.
2010: Claudius Füllhase; Roberto Soler; Christian Gratzke; Marina Brodsky; George Christ; Karl-Erik Andersson
Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction.
The Journal of urology 2010;184(2):783-9.
2010: David Burmeister; Tamer Aboushwareb; Josh Tan; Kerry Link; Karl-Erik Andersson; George Christ
Early stages of in situ bladder regeneration in a rodent model.
Tissue engineering. Part A 2010;16(8):2541-51.
2010: Weixin Zhao; Tamer Aboushwareb; Chanda Turner; Cathy Mathis; Colleen Bennett; William E Sonntag; Karl-Erik Andersson; George Christ
Impaired bladder function in aging male rats.
The Journal of urology 2010;184(1):378-85.
2010: Claudius Füllhase; Roberto Soler; Christian Gratzke; Marina Brodsky; George Christ; Karl-Erik Andersson
Urodynamic evaluation of fesoterodine metabolite, doxazosin and their combination in a rat model of partial urethral obstruction.
BJU international 2010;106(2):287-93.
2010: Christian Gratzke; George Christ; Christian G Stief; Karl-Erik Andersson; Petter Hedlund
Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity.
European urology 2010;57(2):342-8.
2009: George Christ; Wade Bushman; Matthew O Fraser
Impact of diabetes and obesity on the prostate and urethra: implications to improved bladder dysfunction understanding and treatment.
The Journal of urology 2009;182(6 Suppl):S38-44.
2009: George Christ; Karl-Erik Andersson; Koudy Williams; Weixin Zhao; Ralph D'Agostino; Jay Kaplan; Tamer Aboushwareb; James Yoo; Giulia Calenda; Kelvin Davies; Rani S Sellers; Arnold Melman
Smooth-muscle-specific gene transfer with the human maxi-k channel improves erectile function and enhances sexual behavior in atherosclerotic cynomolgus monkeys.
European urology 2009;56(6):1055-66.
2009: Arnold Melman; Lorraine Rojas; George Christ
Gene transfer for erectile dysfunction: will this novel therapy be accepted by urologists?
Current opinion in urology 2009;19(6):595-600.
2009: Daniela M Schlatzer; Jean-Eudes Dazard; Moyez Dharsee; Rob M Ewing; Serguei Ilchenko; Ian Stewart; George Christ; Mark R Chance
Urinary protein profiles in a rat model for diabetic complications.
Molecular & cellular proteomics : MCP 2009;8(9):2145-58.
2009: Mark E Furth; George Christ
Regenerative pharmacology for diabetes mellitus.
Molecular interventions 2009;9(4):171-4.
2009: Weixin Zhao; Yoshikazu Sato; Arnold Melman; Karl-Erik Andersson; George Christ
Metrics for evaluation of age-related changes in erectile capacity in a rodent model.
The journal of sexual medicine 2009;6(7):1885-92.
2009: George Christ
Bladder tissue regeneration.
The Journal of urology 2009;182(1):16-7.
2009: Chad David Markert; Anthony Atala; Jennifer K Cann; George Christ; Mark Furth; Fabrisia Ambrosio; martin childers
Mesenchymal stem cells: emerging therapy for Duchenne muscular dystrophy.
PM & R : the journal of injury, function, and rehabilitation 2009;1(6):547-59.
2009: Aaron S Goldstein; George Christ
Functional tissue engineering requires bioreactor strategies.
Tissue engineering. Part A 2009;15(4):739-40.
2009: Saami K Yazdani; Benjamin Watts; Masood Machingal; Yagna P R Jarajapu; Mark Van Dyke; George Christ
Smooth muscle cell seeding of decellularized scaffolds: the importance of bioreactor preconditioning to development of a more native architecture for tissue-engineered blood vessels.
Tissue engineering. Part A 2009;15(4):827-40.
2009: Christian Gratzke; Tomi Streng; Anthony Park; George Christ; Christian G Stief; Petter Hedlund; Karl-Erik Andersson
Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder.
The Journal of urology 2009;181(4):1939-48.
2009: Tamer Aboushwareb; Ge Zhou; Fang-Ming Deng; Chanda Turner; Karl-Erik Andersson; Moses Tar; Weixin Zhao; Arnold Melman; Ralph D'Agostino; Tung-Tien Sun; George Christ
Alterations in bladder function associated with urothelial defects in uroplakin II and IIIa knockout mice.
Neurourology and urodynamics 2009;28(8):1028-33.
2008: Christian Gratzke; Yagna P R Jarajapu; George Christ; Jay R Kaplan; J Koudy Williams; Karl-Erik Andersson; Gopal Badlani
Effects of long-term dietary soy treatment on female urethral morphology and function in ovariectomized nonhuman primates.
The Journal of urology 2008;180(5):2247-53.
2008: Jin San Choi; Sang Jin Lee; George Christ; Anthony Atala; James J Yoo
The influence of electrospun aligned poly(epsilon-caprolactone)/collagen nanofiber meshes on the formation of self-aligned skeletal muscle myotubes.
Biomaterials 2008;29(19):2899-906.
2008: Elizabeth Yohannes; Jinsook Chang; George Christ; Kelvin Davies; Mark R Chance
Proteomics analysis identifies molecular targets related to diabetes mellitus-associated bladder dysfunction.
Molecular & cellular proteomics : MCP 2008;7(7):1270-85.
2008: Steve J Hodges; Ge Zhou; Fang-Ming Deng; Tamer Aboushwareb; Chanda Turner; Karl-Erik Andersson; Pete Santago; Doug Case; Tung-Tien Sun; George Christ
Voiding pattern analysis as a surrogate for cystometric evaluation in uroplakin II knockout mice.
The Journal of urology 2008;179(5):2046-51.
2008: Du Geon Moon; George Christ; Joel D Stitzel; Anthony Atala; James J Yoo
Cyclic mechanical preconditioning improves engineered muscle contraction.
Tissue engineering. Part A 2008;14(4):473-82.
2008: Arnold Melman; G Biggs; Kelvin Davies; Weixin Zhao; Moses Tar; George Christ
Gene transfer with a vector expressing Maxi-K from a smooth muscle-specific promoter restores erectile function in the aging rat.
Gene therapy 2008;15(5):364-70.
2007: George Christ; Karl-Erik Andersson
Rho-kinase and effects of Rho-kinase inhibition on the lower urinary tract.
Neurourology and urodynamics 2007;26(6 Suppl):948-54.
2007: Kelvin Davies; Weixin Zhao; Moses Tar; Johanna C Figueroa; Pratik Desai; Vytautas Verselis; Jack Kronengold; Hong-Zhan Wang; Arnold Melman; George Christ
Diabetes-induced changes in the alternative splicing of the slo gene in corporal tissue.
European urology 2007;52(4):1229-37.
2007: Elena Zotova; George Christ; Weixin Zhao; Moses Tar; Srini D Kuppam; Joseph C Arezzo
Effects of fidarestat, an aldose reductase inhibitor, on nerve conduction velocity and bladder function in streptozotocin-treated female rats.
Journal of diabetes and its complications 2007;21(3):187-95.
2007: Karl-Erik Andersson; George Christ
Regenerative pharmacology: the future is now.
Molecular interventions 2007;7(2):79-86.
2007: Arnold Melman; Natan Bar-Chama; Andrew McCullough; Kelvin Davies; George Christ
Plasmid-based gene transfer for treatment of erectile dysfunction and overactive bladder: results of a phase I trial.
The Israel Medical Association journal : IMAJ 2007;9(3):143-6.
2007: George Christ; Karl-Erik Andersson; Anthony Atala
The future of bladder research: molecular profiling, new drug targets, gene therapy, and tissue engineering.
Current urology reports 2007;8(2):95-9.
2007: Jason D Hipp; Kelvin Davies; Moses Tar; Mira Valcic; Abraham Knoll; Arnold Melman; George Christ
Using gene chips to identify organ-specific, smooth muscle responses to experimental diabetes: potential applications to urological diseases.
BJU international 2007;99(2):418-30.
2006: Arnold Melman; Natan Bar-Chama; Andrew McCullough; Kelvin Davies; George Christ
hMaxi-K gene transfer in males with erectile dysfunction: results of the first human trial.
Human gene therapy 2006;17(12):1165-76.
2006: H-Z Wang; Peter R Brink; George Christ
Gap junction channel activity in short-term cultured human detrusor myocyte cell pairs: gating and unitary conductances.
American journal of physiology. Cell physiology 2006;291(6):C1366-76.
2006: Yue Hong Tong; Moses Tar; Felix Davelman; George Christ; Arnold Melman; Kelvin Davies
Variable coding sequence protein A1 as a marker for erectile dysfunction.
BJU international 2006;98(2):396-401.
2006: George Christ; Yi Hsieh; Weixin Zhao; Gregory Schenk; Karicheti Venkateswarlu; Hong-Zhan Wang; Moses Tar; Arnold Melman
Effects of streptozotocin-induced diabetes on bladder and erectile (dys)function in the same rat in vivo.
BJU international 2006;97(5):1076-82.
2006: George Christ; Steve Hodges
Molecular mechanisms of detrusor and corporal myocyte contraction: identifying targets for pharmacotherapy of bladder and erectile dysfunction.
British journal of pharmacology 2006;147 Suppl 2():S41-55.
2006: Peter R Brink; Virginijus Valiunas; Hong-Zhan Wang; Weixin Zhao; Kelvin Davies; George Christ
Experimental diabetes alters connexin43 derived gap junction permeability in short-term cultures of rat corporeal vascular smooth muscle cells.
The Journal of urology 2006;175(1):381-6.
2006: Ghada S Hassan; Shankar Mukherjee; Fnu Nagajyothi; Louis M Weiss; Stefka B Petkova; Cecilia J de Almeida; Huan Huang; Mahalia S Desruisseaux; Boumediene Bouzahzah; Richard G Pestell; Chris Albanese; George Christ; Michael P Lisanti; Herbert B Tanowitz
Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells.
Infection and immunity 2006;74(1):152-9.
2005: Arnold Melman; Moses Tar; Judd Boczko; George Christ; Albert C Leung; Weixin Zhao; Robert G Russell
Evaluation of two techniques of partial urethral obstruction in the male rat model of bladder outlet obstruction.
Urology 2005;66(5):1127-33.
2005: George Christ; Christopher Wingard
Calcium sensitization as a pharmacological target in vascular smooth-muscle regulation.
Current opinion in investigational drugs (London, England : 2000) 2005;6(9):920-33.
2005: George Christ
siRNA for erectile dysfunction.
The Journal of urology 2005;174(3):819.
2005: Arnold Melman; Natan Bar-Chama; Andrew McCullough; Kelvin Davies; George Christ
The first human trial for gene transfer therapy for the treatment of erectile dysfunction: preliminary results.
European urology 2005;48(2):314-8.
2005: Judd Boczko; Moses Tar; Arnold Melman; Linda Jelicks; Murray Wittner; Stephen M Factor; Dazhi Zhao; Jason Hafron; Louis M Weiss; Herbert B Tanowitz; George Christ
Trypanosoma cruzi infection induced changes in the innervation, structure and function of the murine bladder.
The Journal of urology 2005;173(5):1784-8.
2005: Naoki Yoshimura; Michael B Chancellor; Karl-Erik Andersson; George Christ
Recent advances in understanding the biology of diabetes-associated bladder complications and novel therapy.
BJU international 2005;95(6):733-8.
2005: Herbert B Tanowitz; Huan Huang; Linda Jelicks; Madhulika Chandra; Maria L Loredo; Louis M Weiss; Stephen M Factor; Vitaliy Shtutin; Shankar Mukherjee; Richard N Kitsis; George Christ; Murray Wittner; Jamshid Shirani; Yaz Y Kisanuki; Masashi Yanagisawa
Role of endothelin 1 in the pathogenesis of chronic chagasic heart disease.
Infection and immunity 2005;73(4):2496-503.
2005: George Christ; Monica Liebert
Proceedings of the Baltimore smooth muscle meeting: identifying research frontiers and priorities for the lower urinary tract.
The Journal of urology 2005;173(4):1406-9.
2004: George Christ
Systems and integrative pharmacology: putting the puzzle pieces together.
Molecular interventions 2004;4(5):240-2.
2004: George Christ; Nancy Day; Cristian Santizo; Yoshi Sato; Weixin Zhao; Theresa Sclafani; Ron Bakal; Masha Salman; Kelvin Davies; Arnold Melman
Intracorporal injection of hSlo cDNA restores erectile capacity in STZ-diabetic F-344 rats in vivo.
American journal of physiology. Heart and circulatory physiology 2004;287(4):H1544-53.
2004: Harin Padma-Nathan; George Christ; Ganesan Adaikan; Edgardo Becher; Gerald B Brock; Serge Carrier; Culley C Carson; Jackie Corbin; Sharon Francis; Robert F DeBusk; Ian Eardley; Hans Hedlund; Adolph Hutter; Graham Jackson; Robert A Kloner; Ching-Shwun Lin; Shin Lin; Kevin T McVary; Andrew McCullough; Ajay Nehra; Hartmut Porst; Claude Schulman; Allen Seftel; Ira D Sharlip; Christian G Stief; Claude Teloken
Pharmacotherapy for erectile dysfunction.
The journal of sexual medicine 2004;1(2):128-40.
2004: Shankar Mukherjee; Huan Huang; Stefka B Petkova; Chris Albanese; Richard G Pestell; Vicki L Braunstein; George Christ; Murray Wittner; Michael P Lisanti; Joan W Berman; Louis M Weiss; Herbert B Tanowitz
Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells.
Infection and immunity 2004;72(9):5274-82.
2004: Tom F Lue; François Giuliano; Francesco Montorsi; Raymond C Rosen; Karl-Erik Andersson; Stanley E Althof; George Christ; Dimitrios Hatzichristou; Mark Hirsch; Yasasuke Kimoto; Ronald W Lewis; Kevin McKenna; Chris MacMahon; Alvaro Morales; John Mulcahy; Harin Padma-Nathan; John Pryor; Inigo Saenz de Tejada; Ridwan Shabsigh; Gorm Wagner
Summary of the recommendations on sexual dysfunctions in men.
The journal of sexual medicine 2004;1(1):6-23.
2004: George Christ; Tom Lue
Physiology and biochemistry of erections.
Endocrine 2004;23(2-3):93-100.
2004: George Christ
Gene therapy treatments for erectile and bladder dysfunction.
Current urology reports 2004;5(1):52-60.
2004: Scott E Woodman; Michelle W-C Cheung; Moses Tarr; Amanda North; William Schubert; Guy Lagaud; Carolyn B Marks; Robert G Russell; Ghada S Hassan; Stephen M Factor; George Christ; Michael P Lisanti
Urogenital alterations in aged male caveolin-1 knockout mice.
The Journal of urology 2004;171(2 Pt 1):950-7.
2003: George Christ
Frontiers in gene therapy for erectile dysfunction.
International journal of impotence research 2003;15 Suppl 5():S33-40.
2003: Arnold Melman; Weixin Zhao; Kelvin Davies; R Bakal; George Christ
The successful long-term treatment of age related erectile dysfunction with hSlo cDNA in rats in vivo.
The Journal of urology 2003;170(1):285-90.
2003: George Christ
Membrane bound guanylyl cyclase as a potential molecular target for the treatment of erectile dysfunction.
The Journal of urology 2003;169(5):1923.
2003: George Christ; Nancy S Day; Michele Day; Weixin Zhao; Katarina Persson; Raj K Pandita; Karl-Erik Andersson
Increased connexin43-mediated intercellular communication in a rat model of bladder overactivity in vivo.
American journal of physiology. Regulatory, integrative and comparative physiology 2003;284(5):R1241-8.
2003: George Christ; Karicheti Venkateswarlu; Nancy S Day; Mira Valcic; Cristian Santizo; Weixin Zhao; Hong-Zhan Wang; Katerina Persson; Karl-Erik Andersson
Intercellular communication and bladder function.
Advances in experimental medicine and biology 2003;539(Pt A):239-54.
2002: Guy Lagaud; Kelvin Davies; K Venkateswarlu; George Christ
The physiology, pathophysiology and therapeutic potential of gap junctions in smooth muscle.
Current drug targets 2002;3(6):427-40.
2002: Guy Lagaud; Venkateswarlu Karicheti; Harry Knot; George Christ; Ismail Laher
Inhibitors of gap junctions attenuate myogenic tone in cerebral arteries.
American journal of physiology. Heart and circulatory physiology 2002;283(6):H2177-86.
2002: George Christ
Gene therapy for erectile dysfunction: where is it going?
Current opinion in urology 2002;12(6):497-501.
2002: Linda Jelicks; Madhulika Chandra; Jamshid Shirani; Vitaliy Shtutin; Baiyu Tang; George Christ; Stephen M Factor; Murray Wittner; Huan Huang; Louis M Weiss; Shankar Mukherjee; Boumediene Bouzahzah; Stefka B Petkova; Mauro Teixeira; Stephen Douglas; Maria L Loredo; Pedro D'Orleans-Juste; Herbert B Tanowitz
Cardioprotective effects of phosphoramidon on myocardial structure and function in murine Chagas' disease.
International journal for parasitology 2002;32(12):1497-506.
2002: Scott E Woodman; David S Park; Alex W Cohen; Michelle W-C Cheung; Madhulika Chandra; Jamshid Shirani; Baiyu Tang; Linda Jelicks; Richard N Kitsis; George Christ; Stephen M Factor; Herbert B Tanowitz; Michael P Lisanti
Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade.
The Journal of biological chemistry 2002;277(41):38988-97.
2002: George Christ
K channels as molecular targets for the treatment of erectile dysfunction.
Journal of andrology 2002;23(5):S10-9.
2002: Nicole Fleischmann; George Christ; Theresa Sclafani; Arnold Melman
The effect of ovariectomy and long-term estrogen replacement on bladder structure and function in the rat.
The Journal of urology 2002;168(3):1265-8.
2002: Lex H T Van der Ploeg; William J Martin; Andrew D Howard; Ravi P Nargund; Christopher P Austin; Xiaoming Guan; Jennifer Drisko; Doreen Cashen; Iyassu Sebhat; Arthur A Patchett; David Figueroa; Anthony G DiLella; Brett M Connolly; David Weinberg; Carina P Tan; Oksana C Palyha; Sheng-Shung Pong; Tanya MacNeil; Charles Rosenblum; Aurawan Vongs; Rui Tang; Hong Yu; Andreas W Sailer; Tung Ming Fong; Cathy Huang; Michael R Tota; Ray S Chang; Ralph Stearns; Constantin Tamvakopoulos; George Christ; Deborah L Drazen; Brian D Spar; Randy J Nelson; D Euan MacIntyre
A role for the melanocortin 4 receptor in sexual function.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(17):11381-6.
2002: Linda Jelicks; Madhulika Chandra; Vitaliy Shtutin; Stefka B Petkova; Baiyu Tang; George Christ; Stephen M Factor; Murray Wittner; Huan Huang; Stephen Douglas; Louis M Weiss; Pedro D' Orleans-Juste; Jamshid Shirani; Herbert B Tanowitz
Phosphoramidon treatment improves the consequences of chagasic heart disease in mice.
Clinical science (London, England : 1979) 2002;103 Suppl 48():267S-271S.
2002: Arnold Melman; George Christ
The hemodynamics of erection and the pharmacotherapies of erectile dysfunction.
Heart disease (Hagerstown, Md.) 2002;4(4):252-64.
2002: K Venkateswarlu; Annamaria Giraldi; Weixin Zhao; Hong-Zang Wang; Arnold Melman; Mariya Spektor; George Christ
Potassium channels and human corporeal smooth muscle cell tone: diabetes and relaxation of human corpus cavernosum smooth muscle by adenosine triphosphate sensitive potassium channel openers.
The Journal of urology 2002;168(1):355-61.
2002: Mariya Spektor; Ramon Rodriguez; Raymond S Rosenbaum; Hong-Zang Wang; Arnold Melman; George Christ
Potassium channels and human corporeal smooth muscle cell tone: further evidence of the physiological relevance of the Maxi-K channel subtype to the regulation of human corporeal smooth muscle tone in vitro.
The Journal of urology 2002;167(6):2628-35.
2002: Babak Razani; Xiao Bo Wang; Jeffery A Engelman; Michela Battista; Guy Lagaud; Xiao Lan Zhang; Burkhard Kneitz; Harry Hou; George Christ; Winfried Edelmann; Michael P Lisanti
Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae.
Molecular and cellular biology 2002;22(7):2329-44.
2001: G Schenk; Arnold Melman; George Christ
Gene therapy: future therapy for erectile dysfunction.
Current urology reports 2001;2(6):480-7.
2001: George Christ; Nancy S Day; M Day; Cristian Santizo; Weixin Zhao; Theresa Sclafani; J Zinman; K Hsieh; K Venkateswarlu; Mira Valcic; Arnold Melman
Bladder injection of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(5):R1699-709.
2001: Babak Razani; Jeffery A Engelman; Xiao Bo Wang; William Schubert; Xiao Lan Zhang; C B Marks; Frank Macaluso; Robert G Russell; Maomi Li; Richard G Pestell; Dolores Di Vizio; Harry Hou; Burkhard Kneitz; Guy Lagaud; George Christ; Winfried Edelmann; Michael P Lisanti
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
The Journal of biological chemistry 2001;276(41):38121-38.
2001: Mostafa El Awady; yehia gad; Y Wen; M Eassawi; LK Effat; Khalda S Amr; S Ismail; George Christ
Schistosoma hematobium soluble egg antigens induce proliferation of urothelial and endothelial cells.
World journal of urology 2001;19(4):263-6.
2001: Yoshi Sato; Weixin Zhao; George Christ
Central modulation of the NO/cGMP pathway affects the MPOA-induced intracavernous pressure response.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(1):R269-78.
2001: Hong-Zang Wang; Nancy Day; Mira Valcic; K Hsieh; S Serels; P R Brink; George Christ
Intercellular communication in cultured human vascular smooth muscle cells.
American journal of physiology. Cell physiology 2001;281(1):C75-88.
2001: Hong-Zang Wang; S W Lee; Nancy S Day; George Christ
Gap junction channel activity in cultured human bladder smooth muscle cell pairs: gating and unitary conductances.
Urology 2001;57(6 Suppl 1):111.
2001: George Christ; Nancy S Day; Cristian Santizo; Weixin Zhao; Theresa Sclafani; Venkateswarlu Karicheti; Mira Valcic; Arnold Melman
Bladder instillation of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo.
Urology 2001;57(6 Suppl 1):111.
2001: Venkateswarlu Karicheti; Cristian Santizo; Weixin Zhao; E Kuo; G Shenk; Arnold Melman; George Christ
Changes in electrical properties of detrusor smooth muscle in the STZ (streptozotocin)-diabetic rat.
Urology 2001;57(6 Suppl 1):110-1.
2001: Hong-Zang Wang; George Christ
K(ATP) channel currents regulate membrane potential in freshly isolated human and rat bladder smooth muscle cells.
Urology 2001;57(6 Suppl 1):110.
2001: Arnold Melman; George Christ
Integrative erectile biology. The effects of age and disease on gap junctions and ion channels and their potential value to the treatment of erectile dysfunction.
The Urologic clinics of North America 2001;28(2):217-31, vii.
2001: Yoshi Sato; J Rehman; Cristian Santizo; Arnold Melman; George Christ
Significant physiological roles of ancillary penile nerves on increase in intracavernous pressure in rats: experiments using electrical stimulation of the medial preoptic area.
International journal of impotence research 2001;13(2):82-8.
2001: Venkateswarlu Karicheti; George Christ
Physiological roles for K+ channels and gap junctions in urogenital smooth muscle: implications for improved understanding of urogenital function, disease and therapy.
Current drug targets 2001;2(1):1-20.
2000: Huan Huang; Stefka B Petkova; Richard G Pestell; Boumediene Bouzahzah; John Chan; H Magazine; Louis M Weiss; George Christ; Michael P Lisanti; Stephen Douglas; Vitaliy Shtutin; Sandra K Halonen; Murray Wittner; Herbert B Tanowitz
Trypanosoma cruzi infection (Chagas' disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S148-50.
2000: M B Noss; Nancy S Day; George Christ; Arnold Melman
The genetics and immunology of Peyronie's disease.
International journal of impotence research 2000;12 Suppl 4():S127-32.
2000: George Christ
Gap junctions and ion channels: relevance to erectile dysfunction.
International journal of impotence research 2000;12 Suppl 4():S15-25.
2000: Stefka B Petkova; Herbert B Tanowitz; H I Magazine; Stephen M Factor; John Chan; Richard G Pestell; Boumediene Bouzahzah; Stephen Douglas; Vitaliy Shtutin; Stephen A Morris; E Tsang; Louis M Weiss; George Christ; Murray Wittner; Huan Huang
Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2000;9(5):257-65.
2000: George Christ; P R Brink
Gap junctions in isolated rat aorta: evidence for contractile responses that exhibit a differential dependence on intercellular communication.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2000;33(4):423-9.
2000: P R Brink; J Ricotta; George Christ
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2000;33(4):415-22.
2000: Y Sato; George Christ
Differential ICP responses elicited by electrical stimulation of medial preoptic area.
American journal of physiology. Heart and circulatory physiology 2000;278(3):H964-70.
2000: Alison D Schecter; Tina M Calderon; Adriane B Berman; C M McManus; John T Fallon; M Rossikhina; Wei Zhao; George Christ; Joan W Berman; Mark B Taubman
Human vascular smooth muscle cells possess functional CCR5.
The Journal of biological chemistry 2000;275(8):5466-71.
2000: George Christ
K+ channels and gap junctions in the modulation of corporal smooth muscle tone.
Drug news & perspectives 2000;13(1):28-36.
2000: George Christ
Gene therapy: future strategies and therapies.
Drugs of today (Barcelona, Spain : 1998) 2000;36(2-3):175-84.
2000: Jamil Rehman; George Christ; M Alyskewycz; E Kerr; Arnold Melman
Experimental hyperprolactinemia in a rat model: alteration in centrally mediated neuroerectile mechanisms.
International journal of impotence research 2000;12(1):23-32.
2000: H Z Wang; S W Lee; George Christ
Comparative studies of the maxi-K (K(Ca)) channel in freshly isolated myocytes of human and rat corpora.
International journal of impotence research 2000;12(1):9-18.
1999: Yasushi Sato; George Christ; Hiroki Horita; Hideki Adachi; Noriyoshi Suzuki; Taiji Tsukamoto
The effects of alterations in nitric oxide levels in the paraventricular nucleus on copulatory behavior and reflexive erections in male rats.
The Journal of urology 1999;162(6):2182-5.
1999: Jamil Rehman; George Christ; AM Kaynan; David B Samadi; J Fleischmann
Intraoperative electrical stimulation of cavernosal nerves with monitoring of intracorporeal pressure in patients undergoing nerve sparing radical prostatectomy.
BJU international 1999;84(3):305-10.
1999: S W Lee; H Z Wang; W Zhao; P Ney; P R Brink; George Christ
Prostaglandin E1 activates the large-conductance KCa channel in human corporal smooth muscle cells.
International journal of impotence research 1999;11(4):189-99.
1999: S W Lee; H Z Wang; George Christ
Characterization of ATP-sensitive potassium channels in human corporal smooth muscle cells.
International journal of impotence research 1999;11(4):179-88.
1999: J Russell; W Zhao; George Christ; S Ashok; Ruth Hogue Angeletti
Ca2+-induced increases in steady-state concentrations of intracellular calcium are not required for inhibition of parathyroid hormone secretion.
Molecular cell biology research communications : MCBRC 1999;1(3):221-6.
1999: George Christ; Mariya Spektor; P R Brink; L Barr
Further evidence for the selective disruption of intercellular communication by heptanol.
The American journal of physiology 1999;276(6 Pt 2):H1911-7.
1999: George Christ; P R Brink
Analysis of the presence and physiological relevance of subconducting states of Connexin43-derived gap junction channels in cultured human corporal vascular smooth muscle cells.
Circulation research 1999;84(7):797-803.
1999: Jamil Rehman; AM Kaynan; George Christ; Mira Valcic; S Maayani; Arnold Melman
Modification of sexual behavior of Long-Evans male rats by drugs acting on the 5-HT1A receptor.
Brain research 1999;821(2):414-25.
1999: M B Noss; George Christ; Arnold Melman
Sildenafil: a new oral therapy for erectile dysfunction.
Drugs of today (Barcelona, Spain : 1998) 1999;35(3):211-7.
1999: Shih-Fang Fan; George Christ; Arnold Melman; P R Brink
A stretch-sensitive Cl- channel in human corpus cavernosal myocytes.
International journal of impotence research 1999;11(1):1-7.
1999: Herbert B Tanowitz; Murray Wittner; Stephen A Morris; Weixin Zhao; Louis M Weiss; Victor Hatcher; Vicki L Braunstein; Huan Huang; Stephen Douglas; Mira Valcic; Mariya Spektor; George Christ
The putative mechanistic basis for the modulatory role of endothelin-1 in the altered vascular tone induced by Trypanosoma cruzi.
Endothelium : journal of endothelial cell research 1999;6(3):217-30.
1998: Annamaria Giraldi; S Serels; M Autieri; Arnold Melman; George Christ
Endothelin-1 as a putative modulator of gene expression and cellular physiology in cultured human corporal smooth muscle cells.
The Journal of urology 1998;160(5):1856-62.
1998: S Serels; Nancy S Day; Y P Wen; Annamaria Giraldi; S W Lee; Arnold Melman; George Christ
Molecular studies of human connexin 43 (Cx43) expression in isolated corporal tissue strips and cultured corporal smooth muscle cells.
International journal of impotence research 1998;10(3):135-43.
1998: M Gondré; George Christ
Endothelin-1-induced alterations in phenylephrine-induced contractile responses are largely additive in physiologically diverse rabbit vasculature.
The Journal of pharmacology and experimental therapeutics 1998;286(2):635-42.
1998: George Christ; Jamil Rehman; Nancy Day; L Salkoff; Mira Valcic; Arnold Melman; J Geliebter
Intracorporal injection of hSlo cDNA in rats produces physiologically relevant alterations in penile function.
The American journal of physiology 1998;275(2 Pt 2):H600-8.
1998: SV Ramanan; Peter R Brink; George Christ
Neuronal innervation, intracellular signal transduction and intercellular coupling: a model for syncytial tissue responses in the steady state.
Journal of theoretical biology 1998;193(1):69-84.
1998: George Christ; Arnold Melman
The application of gene therapy to the treatment of erectile dysfunction.
International journal of impotence research 1998;10(2):111-2.
1998: Jamil Rehman; George Christ; Arnold Melman; J Fleischmann
Intracavernous pressure responses to physical and electrical stimulation of the cavernous nerve in rats.
Urology 1998;51(4):640-4.
1997: George Christ; S Richards; A Winkler
Integrative erectile biology: the role of signal transduction and cell-to-cell communication in coordinating corporal smooth muscle tone and penile erection.
International journal of impotence research 1997;9(2):69-84.
1997: Jamil Rehman; E Chenven; P Brink; B Peterson; Benjamin Walcott; Y P Wen; Arnold Melman; George Christ
Diminished neurogenic but not pharmacological erections in the 2- to 3-month experimentally diabetic F-344 rat.
The American journal of physiology 1997;272(4 Pt 2):H1960-71.
1997: F Staerman; Arnold Melman; Mariya Spektor; George Christ
On the putative mechanistic basis for intraoperative propofol-induced penile erections.
International journal of impotence research 1997;9(1):1-9.
1997: George Christ
The "syncytial tissue triad": a model for understanding how gap junctions participate in the local control of penile erection.
World journal of urology 1997;15(1):36-44.
1996: H Tsai; J Werber; M O Davia; Morris Edelman; Kathryn Tanaka; Arnold Melman; George Christ; J Geliebter
Reduced connexin 43 expression in high grade, human prostatic adenocarcinoma cells.
Biochemical and biophysical research communications 1996;227(1):64-9.
1996: Herbert B Tanowitz; Murray Wittner; B Chen; Huan Huang; Louis M Weiss; George Christ; Vicki L Braunstein; John P Bilezikian; Stephen A Morris
Effects of verapamil on acute murine Chagas' disease.
The Journal of parasitology 1996;82(5):814-9.
1996: George Christ; david spray; M el-Sabban; L K Moore; Peter R Brink
Gap junctions in vascular tissues. Evaluating the role of intercellular communication in the modulation of vasomotor tone.
Circulation research 1996;79(4):631-46.
1996: Peter R Brink; SV Ramanan; George Christ
Human connexin 43 gap junction channel gating: evidence for mode shifts and/or heterogeneity.
The American journal of physiology 1996;271(1 Pt 1):C321-31.
1996: M V Autieri; Arnold Melman; George Christ
Identification of a down-regulated mRNA transcript in corpus cavernosum from diabetic patients with erectile dysfunction.
International journal of impotence research 1996;8(2):69-73.
1996: D Cahn; Arnold Melman; Mira Valcic; George Christ
Forskolin: a promising new adjunct to intracavernous pharmacotherapy.
The Journal of urology 1996;155(5):1789-94.
1996: D C Kim; C M Gondré; George Christ
Endothelin-1-induced modulation of contractile responses elicited by an alpha 1-adrenergic agonist on human corpus cavernosum smooth muscle.
International journal of impotence research 1996;8(1):17-24.
1995: George Christ; D C Kim; H C Taub; C M Gondré; Arnold Melman
Characterization of nitroglycerine-induced relaxation in human corpus cavernosum smooth muscle: implications to erectile physiology and dysfunction.
Canadian journal of physiology and pharmacology 1995;73(12):1714-26.
1995: George Christ
The penis as a vascular organ. The importance of corporal smooth muscle tone in the control of erection.
The Urologic clinics of North America 1995;22(4):727-45.
1995: W Zhao; George Christ
Endothelin-1 as a putative modulator of erectile dysfunction. II. Calcium mobilization in cultured human corporal smooth muscle cells.
The Journal of urology 1995;154(4):1571-9.
1995: George Christ; S E Lerner; D C Kim; Arnold Melman
Endothelin-1 as a putative modulator of erectile dysfunction: I. Characteristics of contraction of isolated corporal tissue strips.
The Journal of urology 1995;153(6):1998-2003.
1995: Shih-Fang Fan; Peter R Brink; Arnold Melman; George Christ
An analysis of the Maxi-K+ (KCa) channel in cultured human corporal smooth muscle cells.
The Journal of urology 1995;153(3 Pt 1):818-25.
1995: Murray Wittner; George Christ; Huan Huang; Louis M Weiss; Victor Hatcher; Stephen A Morris; G A Orr; Joan W Berman; G A Zeballos; Stephen Douglas
Trypanosoma cruzi induces endothelin release from endothelial cells.
The Journal of infectious diseases 1995;171(2):493-7.
1995: George Christ
Modulation of alpha 1-adrenergic contractility in isolated vascular tissues by heptanol: a functional demonstration of the potential importance of intercellular communication to vascular response generation.
Life sciences 1995;56(10):709-21.
1994: George Christ; Arnold Melman; P R Brink
Re: Single potential analysis of cavernous electrical activity in spinal cord injury patients.
The Journal of urology 1994;152(5 Pt 1):1562-3.
1994: Lane S Palmer; Mira Valcic; Arnold Melman; Annamaria Giraldi; G Wagner; George Christ
Characterization of cyclic AMP accumulation in cultured human corpus cavernosum smooth muscle cells.
The Journal of urology 1994;152(4):1308-14.
1994: George Christ; Peter R Brink; SV Ramanan
Dynamic gap junctional communication: a delimiting model for tissue responses.
Biophysical journal 1994;67(3):1335-44.
1994: Peter R Brink; Benjamin Walcott; E Roemer; E Grine; M Pastor; George Christ; R H Cameron
Cholinergic modulation of immunoglobulin secretion from avian plasma cells: the role of calcium.
Journal of neuroimmunology 1994;51(2):113-21.
1994: George Christ; Mira Valcic; M C Gondré
Augmentation in the kinetic characteristics of phenylephrine- and 5-hydroxytryptamine-induced contractions in the isolated rat aorta following eight weeks of STZ-diabetes.
Life sciences 1994;55(10):807-14.
1993: H C Taub; S E Lerner; Arnold Melman; George Christ
Relationship between contraction and relaxation in human and rabbit corpus cavernosum.
Urology 1993;42(6):698-704.
1993: George Christ; david spray; Peter R Brink
Characterization of K currents in cultured human corporal smooth muscle cells.
Journal of andrology 1993;14(5):319-28.
1993: George Christ; Peter R Brink; W Zhao; J Moss; C M Gondré; C Roy; david spray
Gap junctions modulate tissue contractility and alpha 1 adrenergic agonist efficacy in isolated rat aorta.
The Journal of pharmacology and experimental therapeutics 1993;266(2):1054-65.
1993: A C Campos de Carvalho; C Roy; A P Moreno; Arnold Melman; Elliot L Hertzberg; George Christ; david spray
Gap junctions formed of connexin43 are found between smooth muscle cells of human corpus cavernosum.
The Journal of urology 1993;149(6):1568-75.
1993: George Christ; Peter R Brink; Arnold Melman; david spray
The role of gap junctions and ion channels in the modulation of electrical and chemical signals in human corpus cavernosum smooth muscle.
International journal of impotence research 1993;5(2):77-96.
1993: S E Lerner; Arnold Melman; George Christ
A review of erectile dysfunction: new insights and more questions.
The Journal of urology 1993;149(5 Pt 2):1246-55.
1993: A P Moreno; A C Campos de Carvalho; George Christ; Arnold Melman; david spray
Gap junctions between human corpus cavernosum smooth muscle cells: gating properties and unitary conductance.
The American journal of physiology 1993;264(1 Pt 1):C80-92.
1992: George Christ; A P Moreno; Arnold Melman; david spray
Gap junction-mediated intercellular diffusion of Ca2+ in cultured human corporal smooth muscle cells.
The American journal of physiology 1992;263(2 Pt 1):C373-83.
1992: George Christ; C B Schwartz; B A Stone; M Parker; M Janis; M Gondre; Mira Valcic; Arnold Melman
Kinetic characteristics of alpha 1-adrenergic contractions in human corpus cavernosum smooth muscle.
The American journal of physiology 1992;263(1 Pt 2):H15-9.
1991: George Christ; B Stone; Arnold Melman
Age-dependent alterations in the efficacy of phenylephrine-induced contractions in vascular smooth muscle isolated from the corpus cavernosum of impotent men.
Canadian journal of physiology and pharmacology 1991;69(7):909-13.
1991: George Christ; M Jean-Jacques
Mutual-effect amplification of contractile responses elicited by simultaneous activation of alpha-1 adrenergic and 5-hydroxytryptamine2 receptors in isolated rat aorta.
The Journal of pharmacology and experimental therapeutics 1991;256(2):553-61.
1991: George Christ; A P Moreno; M E Parker; C M Gondre; Mira Valcic; Arnold Melman; david spray
Intercellular communication through gap junctions: a potential role in pharmacomechanical coupling and syncytial tissue contraction in vascular smooth muscle isolated from the human corpus cavernosum.
Life sciences 1991;49(24):PL195-200.
1990: George Christ; S Maayani; Mira Valcic; Arnold Melman
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues.
British journal of pharmacology 1990;101(2):375-81.
1990: George Christ; J Goldfarb; S Maayani
Receptor-mediated mutual-effect amplification elicited by phenylephrine and serotonin in isolated rabbit aorta.
The Journal of pharmacology and experimental therapeutics 1990;252(2):500-6.
1990: George Christ
Determination of agonist dissociation constants in isolated vasculature: equivalence of estimates obtained by the method of partial irreversible receptor inactivation and a novel application of the operational model of pharmacological agonism.
Life sciences 1990;47(20):1867-74.
1988: George Christ; C E Dunlap; David A Blizard
Genetic influences on agonist binding to cardiac beta-receptors.
Biochemical pharmacology 1988;37(7):1281-6.
1988: George Christ; John A Pieper; David A Blizard; C E Dunlap
Effects of stress and chronic propranolol infusion on cardiac beta-receptor function in the Maudsley Reactive and Non-Reactive rat strains.
Life sciences 1988;43(22):1773-84.
1986: C E Dunlap; George Christ; J C Rose
Characterization of opioid receptor binding in adult and fetal sheep brain regions.
Brain research 1986;389(1-2):279-85.