FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Richard Gordon

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Co-author Network

Publications

TOP 3
Apurba K Bhattacharjee; Sarah A Evans; Dmitry Pervitsky; James W Pomponio; Richard Gordon
Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods.
Apurba K Bhattacharjee; Kamil Kuca; Kamil Musilek; Richard Gordon
An in silico stereo-electronic comparison of conventional pyridinium oximes and K-oximes for organophosphate (OP) poisoning.
Apurba K Bhattacharjee; Ha Thu Le; Elizabeth Marek; Richard Gordon
Discovery of non-oxime reactivators using an in silico pharmacophore model of oxime reactivators of OP-inhibited acetylcholinesterase.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Richard Gordon (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Apurba K Bhattacharjee; Sarah A Evans; Dmitry Pervitsky; James W Pomponio; Richard Gordon
Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods.
Bioorganic & medicinal chemistry 2013;21(9):2651-62.
2012: Apurba K Bhattacharjee; Kamil Kuca; Kamil Musilek; Richard Gordon
An in silico stereo-electronic comparison of conventional pyridinium oximes and K-oximes for organophosphate (OP) poisoning.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2012;8(2):230-45.
2012: Apurba K Bhattacharjee; Ha Thu Le; Elizabeth Marek; Richard Gordon
Discovery of non-oxime reactivators using an in silico pharmacophore model of oxime reactivators of OP-inhibited acetylcholinesterase.
European journal of medicinal chemistry 2012;49():229-38.
2010: James C Demar; Edward D Clarkson; Ruthie H Ratcliffe; Amy J Campbell; Sonia G Thangavelu; Christine A Herdman; Haim Leader; Susan M Schulz; Elizabeth Marek; Marie A Medynets; Therese C Ku; Sarah A Evans; Farhat A Khan; Roberta R Owens; Madhusoodana P Nambiar; Richard Gordon
Pro-2-PAM therapy for central and peripheral cholinesterases.
Chemico-biological interactions 2010;187(1-3):191-8.
2010: Julian R Haigh; Michael Adler; James P Apland; Sharad S Deshpande; Charles B Barham; Patrick Desmond; Irwin Koplovitz; David Lenz; Richard Gordon
Protection by pyridostigmine bromide of marmoset hemi-diaphragm acetylcholinesterase activity after soman exposure.
Chemico-biological interactions 2010;187(1-3):416-20.
2010: Apurba K Bhattacharjee; Kamil Kuca; Kamil Musilek; Richard Gordon
In silico pharmacophore model for tabun-inhibited acetylcholinesterase reactivators: a study of their stereoelectronic properties.
Chemical research in toxicology 2010;23(1):26-36.
2009: Xuerong Shi; Jennifer E Curran; Zhilin Liao; Richard Gordon
The biological activity of ubiquitinated BoNT/B light chain in vitro and in human SHSY-5Y neuronal cells.
Journal of cellular biochemistry 2009;108(3):660-7.
2009: Magnus M Che; Michele Conti; Soma Chanda; Megan Boylan; Praveena Sabnekar; Peter Rezk; Ethery Amari; Alfred M Sciuto; Richard Gordon; Bhupendra P Doctor; Madhusoodana P Nambiar
Post-exposure treatment with nasal atropine methyl bromide protects against microinstillation inhalation exposure to sarin in guinea pigs.
Toxicology and applied pharmacology 2009;239(3):251-7.
2009: Michele L Conti; Magnus M Che; Megan Boylan; Alfred M Sciuto; Richard Gordon; Madhusoodana P Nambiar
Acute microinstillation inhalation exposure to sarin induces changes in respiratory dynamics and functions in guinea pigs.
International journal of toxicology 2009;28(5):436-47.
2009: Xuerong Shi; Gregory E Garcia; Roger J Neill; Richard Gordon
TCEP treatment reduces proteolytic activity of BoNT/B in human neuronal SHSY-5Y cells.
Journal of cellular biochemistry 2009;107(5):1021-30.
2009: Apurba K Bhattacharjee; Jonathan A Gordon; Elizabeth Marek; Amy Campbell; Richard Gordon
3D-QSAR studies of 2,2-diphenylpropionates to aid discovery of novel potent muscarinic antagonists.
Bioorganic & medicinal chemistry 2009;17(11):3999-4012.
2009: Alexandre M Katos; Michele Conti; Theodore S Moran; Thomas W Chon; Richard Gordon; Alfred M Sciuto; Bhupendra P Doctor; Madhusoodana P Nambiar
Acute microinstillation inhalation exposure to soman induces changes in respiratory dynamics and functions in guinea pigs.
Inhalation toxicology 2009;21(7):1-10.
2008: Brian R Coleman; Ruthie H Ratcliffe; Samuel A Oguntayo; Xuerong Shi; Bhupendra P Doctor; Richard Gordon; Madhusoodana P Nambiar
[+]-Huperzine A treatment protects against N-methyl-D-aspartate-induced seizure/status epilepticus in rats.
Chemico-biological interactions 2008;175(1-3):387-95.
2008: Julian R Haigh; Scott R Johnston; Adam Peppernay; Patrick J Mattern; Gregory E Garcia; Bhupendra P Doctor; Richard Gordon; Paul S Aisen
Protection of red blood cell acetylcholinesterase by oral huperzine A against ex vivo soman exposure: next generation prophylaxis and sequestering of acetylcholinesterase over butyrylcholinesterase.
Chemico-biological interactions 2008;175(1-3):380-6.
2008: Julian R Haigh; Lee J Lefkowitz; Benedict R Capacio; Bhupendra P Doctor; Richard Gordon
Advantages of the WRAIR whole blood cholinesterase assay: comparative analysis to the micro-Ellman, Test-mate ChE, and Michel (DeltapH) assays.
Chemico-biological interactions 2008;175(1-3):417-20.
2008: Xuerong Shi; Gregory E Garcia; Madhusoodana P Nambiar; Richard Gordon
Un-nicked BoNT/B activity in human SHSY-5Y neuronal cells.
Journal of cellular biochemistry 2008;105(1):129-35.
2008: Magnus M Che; Michele Conti; Megan Boylan; Alfred M Sciuto; Richard Gordon; Madhusoodana P Nambiar
Blood and bronchoalveolar lavage fluid acetylcholinesterase levels following microinstillation inhalation exposure to sarin in Guinea pigs.
Inhalation toxicology 2008;20(9):821-8.
2008: Bryan F Curtin; Karthik I Seetharam; Pilin Dhoieam; Richard Gordon; Bhupendra P Doctor; Madhusoodana P Nambiar
Resveratrol induces catalytic bioscavenger paraoxonase 1 expression and protects against chemical warfare nerve agent toxicity in human cell lines.
Journal of cellular biochemistry 2008;103(5):1524-35.
2007: Alexandre M Katos; Michele L Conti; Theodore S Moran; Richard Gordon; Bhupendra P Doctor; Alfred M Sciuto; Madhusoodana P Nambiar
Abdominal bloating and irritable bowel syndrome like symptoms following microinstillation inhalation exposure to chemical warfare nerve agent VX in guinea pigs.
Toxicology and industrial health 2007;23(4):231-40.
2007: Peter E Rezk; Jacob R Graham; Theodore S Moran; Richard Gordon; Alfred M Sciuto; Bhupendra P Doctor; Madhusoodana P Nambiar
Acute toxic effects of nerve agent VX on respiratory dynamics and functions following microinsillation inhalation exposure in guinea pigs.
Inhalation toxicology 2007;19(3):291-302.
2007: Madhusoodana P Nambiar; Richard Gordon; Peter E Rezk; Alexander M Katos; Nikolai A Wajda; Theodore S Moran; Keith E Steele; Bhupendra P Doctor; Alfred M Sciuto
Medical countermeasure against respiratory toxicity and acute lung injury following inhalation exposure to chemical warfare nerve agent VX.
Toxicology and applied pharmacology 2007;219(2-3):142-50.
2007: Madhusoodana P Nambiar; Richard Gordon; Theodore S Moran; S M Richards; Alfred M Sciuto
A simple method for accurate endotracheal placement of an intubation tube in Guinea pigs to assess lung injury following chemical exposure.
Toxicology mechanisms and methods 2007;17(7):385-92.
2007: Myriane A Isidore; Michael P Castagna; Keith E Steele; Richard Gordon; Madhusoodana P Nambiar
A dorsal model for cutaneous vesicant injury by 2-chloroethyl ethyl sulfide using C57BL/6 mice.
Cutaneous and ocular toxicology 2007;26(3):265-76.
2006: Bryan F Curtin; Nabaneeta Pal; Richard Gordon; Madhusoodana P Nambiar
Forskolin, an inducer of cAMP, up-regulates acetylcholinesterase expression and protects against organophosphate exposure in neuro 2A cells.
Molecular and cellular biochemistry 2006;290(1-2):23-32.
2006: Lauren M Tetz; Peter E Rezk; Ruthie H Ratcliffe; Richard Gordon; Keith E Steele; Madhusoodana P Nambiar
Development of a rat pilocarpine model of seizure/status epilepticus that mimics chemical warfare nerve agent exposure.
Toxicology and industrial health 2006;22(6):255-66.
2006: Jacob R Graham; Benjamin S Wright; Peter E Rezk; Richard Gordon; Alfred M Sciuto; Madhusoodana P Nambiar
Butyrylcholinesterase in guinea pig lung lavage: a novel biomarker to assess lung injury following inhalation exposure to nerve agent VX.
Inhalation toxicology 2006;18(7):493-500.
2006: Benjamin S Wright; Peter E Rezk; Jacob R Graham; Keith E Steele; Richard Gordon; Alfred M Sciuto; Madhusoodana P Nambiar
Acute lung injury following inhalation exposure to nerve agent VX in guinea pigs.
Inhalation toxicology 2006;18(6):437-48.
2006: Madhusoodana P Nambiar; Benjamin S Wright; Peter E Rezk; Kelvin B Smith; Richard Gordon; Theodore S Moran; Shannon M Richards; Alfred M Sciuto
Development of a microinstillation model of inhalation exposure to assess lung injury following exposure to toxic chemicals and nerve agents in Guinea pigs.
Toxicology mechanisms and methods 2006;16(6):295-306.
2006: Praful B Godkar; Richard Gordon; Arippa Ravindran; Bhupendra P Doctor
Celastrus paniculatus seed oil and organic extracts attenuate hydrogen peroxide- and glutamate-induced injury in embryonic rat forebrain neuronal cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2006;13(1-2):29-36.
2005: Julian R Haigh; Scott R Johnston; Brian M Peters; Bhupendra P Doctor; Richard Gordon; Michael Adler; Kenneth J Gall; Sharad S Deshpande
Inhibition of guinea pig hemi-diaphragm acetylcholinesterase activity by pyridostigmine bromide and protection against soman toxicity.
Chemico-biological interactions 2005;157-158():381-2.
2005: Madhusoodana P Nambiar; Bryan F Curtin; Nabaneeta Pal; J R Compton; Bhupendra P Doctor; Richard Gordon
Transcriptional induction of cholinesterase expression and protection against chemical warfare nerve agents.
Chemico-biological interactions 2005;157-158():409-10.
2005: Richard Gordon; Julian R Haigh; Gregory E Garcia; Shawn R Feaster; Michael A Riel; David Lenz; Paul S Aisen; Bhupendra P Doctor
Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman.
Chemico-biological interactions 2005;157-158():239-46.
2005: Bryan F Curtin; Lauren M Tetz; Jaimee R Compton; Bhupendra P Doctor; Richard Gordon; Madhusoodana P Nambiar
Histone acetylase inhibitor trichostatin A induces acetylcholinesterase expression and protects against organophosphate exposure.
Journal of cellular biochemistry 2005;96(4):839-49.
2004: Praful B Godkar; Richard Gordon; Arippa Ravindran; Bhupendra P Doctor
Celastrus paniculatus seed water soluble extracts protect against glutamate toxicity in neuronal cultures from rat forebrain.
Journal of ethnopharmacology 2004;93(2-3):213-9.
2003: Praful B Godkar; Richard Gordon; Arippa Ravindran; Bhupendra P Doctor
Celastrus paniculatus seed water soluble extracts protect cultured rat forebrain neuronal cells from hydrogen peroxide-induced oxidative injury.
Fitoterapia 2003;74(7-8):658-69.
2003: Richard Gordon; Krzysztof Ginalski; Witold R Rudnicki; Leszek Rychlewski; Marvin C Pankaskie; Janusz Bujnicki; Peter K Chiang
Anti-HIV-1 activity of 3-deaza-adenosine analogs. Inhibition of S-adenosylhomocysteine hydrolase and nucleotide congeners.
European journal of biochemistry / FEBS 2003;270(17):3507-17.
2002: Haim Leader; Alan David Wolfe; Peter K Chiang; Richard Gordon
Pyridophens: binary pyridostigmine-aprophen prodrugs with differential inhibition of acetylcholinesterase, butyrylcholinesterase, and muscarinic receptors.
Journal of medicinal chemistry 2002;45(4):902-10.
2001: Richard Gordon; S V Nigam; J A Weitz; Jitendra R Dave; Bhupendra P Doctor; Haresh S Ved
The NMDA receptor ion channel: a site for binding of Huperzine A.
Journal of applied toxicology : JAT 2001;21 Suppl 1():S47-51.
1999: Gregory E Garcia; D R Moorad; Richard Gordon
Buforin I, a natural peptide, inhibits botulinum neurotoxin B activity in vitro.
Journal of applied toxicology : JAT 1999;19 Suppl 1():S19-22.
1999: Richard Gordon; Shawn R Feaster; Alan Russell; KE LeJeune; david e lenz; David Lenz; M Ross; Bhupendra P Doctor
Organophosphate skin decontamination using immobilized enzymes.
Chemico-biological interactions 1999;119-120():463-70.
1999: Donald M Maxwell; A Saxena; Richard Gordon; Bhupendra P Doctor
Improvements in scavenger protection against organophosphorus agents by modification of cholinesterases.
Chemico-biological interactions 1999;119-120():419-28.
1996: P K Chiang; Richard Gordon; J Tal; G C Zeng; Bhupendra P Doctor; K Pardhasaradhi; P P McCann
S-Adenosylmethionine and methylation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(4):471-80.
1995: D L Mayers; J A Mikovits; B Joshi; I K Hewlett; J S Estrada; A D Wolfe; G E Garcia; Bhupendra P Doctor; Donald S. Burke; Richard Gordon
Anti-human immunodeficiency virus 1 (HIV-1) activities of 3-deazaadenosine analogs: increased potency against 3'-azido-3'-deoxythymidine-resistant HIV-1 strains.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):215-9.
1993: N D Brown; Haim Leader; L R Phillips; R M Smejkal; Richard Gordon; P K Chiang
Synthesis and antimuscarinic activity of 2-[N-(ethyl)-(N-beta-hydroxyethyl)]aminoethyl 2,2-diphenylpropionate, a metabolite of aprophen.
Journal of pharmaceutical sciences 1993;82(6):563-4.
1992: Richard Gordon; R R Gray; C B Reaves; D L Butler; P K Chiang
Induced release of acetylcholine from guinea pig ileum longitudinal muscle-myenteric plexus by anatoxin-a.
The Journal of pharmacology and experimental therapeutics 1992;263(3):997-1002.
1992: P Kostka; S Ahmad; chiu-yin kwan; E E Daniel; Richard Gordon; P K Chiang
Prejunctional muscarinic receptors in the deep muscular plexus of canine ileum: comparison with smooth muscle receptors.
The Journal of pharmacology and experimental therapeutics 1992;263(1):226-31.
1992: Haim Leader; Richard Gordon; J Baumgold; V L Boyd; Amy Hauck Newman; R M Smejkal; P K Chiang
Muscarinic receptor subtype specificity of (N,N-dialkylamino)alkyl 2-cyclohexyl-2-phenylpropionates: cylexphenes (cyclohexyl-substituted aprophen analogues).
Journal of medicinal chemistry 1992;35(7):1290-5.
1992: Jean M Karle; I L Karle; Richard Gordon; P K Chiang
Relationship of three-dimensional structure of muscarinic antagonists to antimuscarinic activity: structure of thiodeacylaprophen hydrochloride.
Acta crystallographica. Section B, Structural science 1992;48 ( Pt 2)():208-13.
1992: P K Chiang; P D Burbelo; S A Brugh; Richard Gordon; K Fukuda; Y Yamada
Activation of collagen IV gene expression in F9 teratocarcinoma cells by 3-deazaadenosine analogs. Indirect inhibitors of methylation.
The Journal of biological chemistry 1992;267(7):4988-91.
1992: P K Chiang; J Katzhendler; Richard Gordon; Bhupendra P Doctor; N D Brown
Postganglionic nicotinic action of anatoxin-a on guinea pig ileum antagonized by thymopentin.
Advances in experimental medicine and biology 1992;311():429-30.
1990: Richard Gordon; R R Gray; P K Chiang
Vasoactive intestinal polypeptides induce guinea-pig ileum contraction by causing release of endogenous acetylcholine.
Archives internationales de pharmacodynamie et de thérapie 1990;305():14-24.
1989: Richard Gordon; P K Chiang
Differential allosteric effects of 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate-HCl (TMB-8) on muscarinic receptor subtypes.
FEBS letters 1989;257(2):383-7.
1989: Richard Gordon; E Breuer; F N Padilla; R M Smejkal; P K Chiang
Distance geometry of alpha-substituted 2,2-diphenylpropionate antimuscarinics.
Molecular pharmacology 1989;36(5):766-72.
1989: J A Duerre; Richard Gordon
Characterization of the binding of S-adenosyl-L-methionine to plasma membranes of HL-60 promyelocytic leukemia cells.
Biochimica et biophysica acta 1989;985(2):211-7.
1989: Haim Leader; R M Smejkal; C S Payne; F N Padilla; Bhupendra P Doctor; Richard Gordon; P K Chiang
Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates.
Journal of medicinal chemistry 1989;32(7):1522-8.
1989: Richard Gordon; R M Smejkal; E Breuer; P K Chiang
Design and synthesis of antimuscarinics based on physical and mechanical attributes.
Progress in clinical and biological research 1989;289():465-70.
1987: Jeffrey M Witkin; Richard Gordon; P K Chiang
Comparison of in vitro actions with behavioral effects of antimuscarinic agents.
The Journal of pharmacology and experimental therapeutics 1987;242(3):796-803.
1987: A Ahmad; Richard Gordon; P K Chiang
A microtechnique for quantification of detergent-solubilized muscarinic and nicotinic acetylcholine receptors using a semi-automated cell harvestor.
FEBS letters 1987;214(2):285-90.
1987: Richard Gordon; G A Miura; T Alonso; P K Chiang
S-adenosylmethionine and its sulfur metabolites.
Methods in enzymology 1987;143():191-5.
1986: Jarle Aarbakke; G A Miura; N D Brown; R R Gray; Richard Gordon; Bhupendra P Doctor; P K Chiang
Disposition of aprophen in rats.
The Journal of pharmacy and pharmacology 1986;38(12):928-30.
1986: Jarle Aarbakke; G A Miura; P S Prytz; A Bessesen; L Slørdal; Richard Gordon; P K Chiang
Induction of HL-60 cell differentiation by 3-deaza-(+/-)-aristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase.
Cancer research 1986;46(11):5469-72.
1986: L A Liotta; R Mandler; G Murano; D A Katz; Richard Gordon; P K Chiang; E Schiffmann
Tumor cell autocrine motility factor.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(10):3302-6.
1986: J M Whaun; G A Miura; N D Brown; Richard Gordon; P K Chiang
Antimalarial activity of neplanocin A with perturbations in the metabolism of purines, polyamines and S-adenosylmethionine.
The Journal of pharmacology and experimental therapeutics 1986;236(1):277-83.
1986: Richard Gordon; P K Chiang
Antimuscarinic activities of hycanthone analogs: possible relationship with animal toxicity.
The Journal of pharmacology and experimental therapeutics 1986;236(1):85-9.
1986: G A Miura; Richard Gordon; J A Montgomery; P K Chiang
4'-Thioadenosine as a novel inhibitor of S-adenosylhomocysteine hydrolase and an inducer for the differentiation of HL-60 human leukemia cells.
Advances in experimental medicine and biology 1986;195 Pt B():667-72.
1986: G A Miura; P K Chiang; Richard Gordon; Bhupendra P Doctor; C E Twine; A Philip; J A Kepler; F I Carroll
Enzymatic synthesis of a false cholinergic neurotransmitter: diethylaminoethyl acetate as a muscarinic agonist analog of acetylcholine.
General pharmacology 1986;17(4):477-80.
1985: M C Pankaskie; J F Kachur; T Itoh; Richard Gordon; P K Chiang
Inhibition of muscarinic receptor binding and acetylcholine-induced contraction of guinea pig ileum by analogues of 5'-(isobutylthio)adenosine.
Journal of medicinal chemistry 1985;28(8):1117-9.
1984: G A Miura; J R Santangelo; Richard Gordon; P K Chiang
Analysis of S-adenosylmethionine and related sulfur metabolites in animal tissues.
Analytical biochemistry 1984;141(1):161-7.
1983: Richard Gordon; F N Padilla; E Moore; Bhupendra P Doctor; P K Chiang
Antimuscarinic activity of aprophen.
Biochemical pharmacology 1983;32(19):2979-81.
1983: Richard Gordon; N D Brown; P K Chiang
Inhibition of adenosylmethionine decarboxylase and perturbation of polyamine metabolism by 3-deaza-(+/-)aristeromycin.
Biochemical and biophysical research communications 1983;114(2):505-10.
1982: Richard Gordon; Bhupendra P Doctor; P K Chiang
A radioactive assay for acetylcholinesterase using anion-exchange disk.
Analytical biochemistry 1982;124(2):333-7.