FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Andrew Gulick

Research Profile

Procedures

X Ray Crystallography

Concepts & Ideas

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Phenomena

Living Beings

Escherichia coli

Physiology

Mutagenesis, Site-Directed

Co-author Network

Publications

TOP 3
João Neres; Daniel J Wilson; Clifton E Barry; Helena I Boshoff; Eric J Drake; Curtis A Engelhart; Peng Fu; Andrew Gulick; Courtney C Aldrich
Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.
Daniel J Wilson; Andrew Gulick; Ce Shi; Aaron M Teitelbaum; Courtney C Aldrich
Characterization of AusA: a dimodular nonribosomal peptide synthetase responsible for the production of aureusimine pyrazinones.
Jesse A Sundlov; Tara L Southworth; Bruce R Branchini; Danielle M Fontaine; Andrew Gulick
Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Andrew Gulick (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: João Neres; Daniel J Wilson; Clifton E Barry; Helena I Boshoff; Eric J Drake; Curtis A Engelhart; Peng Fu; Andrew Gulick; Courtney C Aldrich
Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.
Journal of medicinal chemistry 2013;56(6):2385-405.
2013: Daniel J Wilson; Andrew Gulick; Ce Shi; Aaron M Teitelbaum; Courtney C Aldrich
Characterization of AusA: a dimodular nonribosomal peptide synthetase responsible for the production of aureusimine pyrazinones.
Biochemistry 2013;52(5):926-37.
2012: Jesse A Sundlov; Tara L Southworth; Bruce R Branchini; Danielle M Fontaine; Andrew Gulick
Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism.
Biochemistry 2012;51(33):6493-5.
2012: Carter A Mitchell; Ce Shi; Courtney C Aldrich; Andrew Gulick
Structure of PA1221, a nonribosomal peptide synthetase containing adenylation and peptidyl carrier protein domains.
Biochemistry 2012;51(15):3252-63.
2012: Jesse A Sundlov; Daniel J Wilson; Courtney C Aldrich; Ce Shi; Andrew Gulick
Structural and functional investigation of the intermolecular interaction between NRPS adenylation and carrier protein domains.
Chemistry & biology 2012;19(2):188-98.
2011: Eric J Drake; Andrew Gulick
Structural characterization and high-throughput screening of inhibitors of PvdQ, an NTN hydrolase involved in pyoverdine synthesis.
ACS chemical biology 2011;6(11):1277-86.
2010: Eric J Drake; Benjamin P Duckworth; João Neres; Courtney C Aldrich; Andrew Gulick
Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis.
Biochemistry 2010;49(43):9292-305.
2009: Jesse A Sundlov; Andrew Gulick
Insights into resistance against lincosamide antibiotics.
Structure (London, England : 1993) 2009;17(12):1549-50.
2009: Manish Shah; Cheryl Ingram-Smith; Leroy L Cooper; Jun Qu; Yu Meng; Kerry S Smith; Andrew Gulick
The 2.1 A crystal structure of an acyl-CoA synthetase from Methanosarcina acetivorans reveals an alternate acyl-binding pocket for small branched acyl substrates.
Proteins 2009;77(3):685-98.
2009: Andrew Gulick
Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase.
ACS chemical biology 2009;4(10):811-27.
2009: Rui Wu; Albert S Reger; Xuefeng Lu; Andrew Gulick; Debra Dunaway-Mariano
The mechanism of domain alternation in the acyl-adenylate forming ligase superfamily member 4-chlorobenzoate: coenzyme A ligase.
Biochemistry 2009;48(19):4115-25.
2009: Andrew Gulick
Ironing out a new siderophore synthesis strategy.
Nature chemical biology 2009;5(3):143-4.
2008: Eric J Drake; Andrew Gulick
Three-dimensional structures of Pseudomonas aeruginosa PvcA and PvcB, two proteins involved in the synthesis of 2-isocyano-6,7-dihydroxycoumarin.
Journal of molecular biology 2008;384(1):193-205.
2008: Rui Wu; Jian Cao; Xuefeng Lu; Albert S Reger; Andrew Gulick; Debra Dunaway-Mariano
Mechanism of 4-chlorobenzoate:coenzyme a ligase catalysis.
Biochemistry 2008;47(31):8026-39.
2008: Albert S Reger; Rui Wu; Debra Dunaway-Mariano; Andrew Gulick
Structural characterization of a 140 degrees domain movement in the two-step reaction catalyzed by 4-chlorobenzoate:CoA ligase.
Biochemistry 2008;47(31):8016-25.
2007: Rui Wu; Albert S Reger; Jian Cao; Andrew Gulick; Debra Dunaway-Mariano
Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range.
Biochemistry 2007;46(50):14487-99.
2007: Eric J Drake; Jin Cao; jun qu; Manish Shah; Robert M Straubinger; Andrew Gulick
The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa.
The Journal of biological chemistry 2007;282(28):20425-34.
2007: Albert S Reger; Jill M Carney; Andrew Gulick
Biochemical and crystallographic analysis of substrate binding and conformational changes in acetyl-CoA synthetase.
Biochemistry 2007;46(22):6536-46.
2006: Jesse A Sundlov; Julie A Garringer; Jill M Carney; Albert S Reger; Eric J Drake; William L Duax; Andrew Gulick
Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 7):734-40.
2006: Eric J Drake; David A Nicolai; Andrew Gulick
Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain.
Chemistry & biology 2006;13(4):409-19.
2005: Yangzhou Wang; Lin Feng; Meriem Said; Sophia Balderman; Zahra Fayazi; Yu Liu; Debashis Ghosh; Andrew Gulick
Analysis of the 2.0 A crystal structure of the protein-DNA complex of the human PDEF Ets domain bound to the prostate specific antigen regulatory site.
Biochemistry 2005;44(19):7095-106.
2004: Andrew Gulick; Xuefeng Lu; Debra Dunaway-Mariano
Crystal structure of 4-chlorobenzoate:CoA ligase/synthetase in the unliganded and aryl substrate-bound states.
Biochemistry 2004;43(27):8670-9.
2003: Andrew Gulick; Vincent Starai; Alexander R Horswill; Kristen M Homick; Jorge C Escalante-Semerena
The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A.
Biochemistry 2003;42(10):2866-73.
2002: Andrew Gulick; Alexander R Horswill; James B Thoden; Jorge C Escalante-Semerena; Ivan Rayment
Pentaerythritol propoxylate: a new crystallization agent and cryoprotectant induces crystal growth of 2-methylcitrate dehydratase.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 2):306-9.
2001: Andrew Gulick; Dawn M Z Schmidt; John Alan Gerlt; Ivan Rayment
Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis.
Biochemistry 2001;40(51):15716-24.
2001: Andrew Gulick; BK Hubbard; John Alan Gerlt; Ivan Rayment
Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli.
Biochemistry 2001;40(34):10054-62.
2000: Andrew Gulick; BK Hubbard; John Alan Gerlt; Ivan Rayment
Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli.
Biochemistry 2000;39(16):4590-602.
2000: Andrew Gulick; Cay Brian Bauer; James B Thoden; Edward Pate; Ralph G Yount; Ivan Rayment
X-ray structures of the Dictyostelium discoideum myosin motor domain with six non-nucleotide analogs.
The Journal of biological chemistry 2000;275(1):398-408.
1998: Andrew Gulick; DR Palmer; Patricia C Babbitt; John Alan Gerlt; Ivan Rayment
Evolution of enzymatic activities in the enolase superfamily: crystal structure of (D)-glucarate dehydratase from Pseudomonas putida.
Biochemistry 1998;37(41):14358-68.
1998: Andrew Gulick; H Song; S A Endow; Ivan Rayment
X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution.
Biochemistry 1998;37(7):1769-76.
1997: Andrew Gulick; Cay Brian Bauer; James B Thoden; Ivan Rayment
X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain.
Biochemistry 1997;36(39):11619-28.
1997: James B Thoden; Andrew Gulick; Hazel M Holden
Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry 1997;36(35):10685-95.
1997: Y Liu; James B Thoden; J Kim; E Berger; Andrew Gulick; Frank J Ruzicka; Hazel M Holden; Perry A Frey
Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry 1997;36(35):10675-84.
1997: H T Manoharan; J Gallo; Andrew Gulick; William E Fahl
High-level production and purification of biologically active proteins from bacterial and mammalian cells using the tandem pGFLEX expression system.
Gene 1997;193(2):229-37.
1997: Andrew Gulick; Ivan Rayment
Structural studies on myosin II: communication between distant protein domains.
BioEssays : news and reviews in molecular, cellular and developmental biology 1997;19(7):561-9.
1995: Andrew Gulick; William E Fahl
Forced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8140-4.
1995: Andrew Gulick; William E Fahl
Mammalian glutathione S-transferase: regulation of an enzyme system to achieve chemotherapeutic efficacy.
Pharmacology & therapeutics 1995;66(2):237-57.
1992: Andrew Gulick; A L Goihl; William E Fahl
Structural studies on human glutathione S-transferase pi. Family of native-specific monoclonal antibodies used to block catalysis.
The Journal of biological chemistry 1992;267(26):18946-52.
1992: T H Manoharan; Andrew Gulick; R B Puchalski; A L Servais; William E Fahl
Structural studies on human glutathione S-transferase pi. Substitution mutations to determine amino acids necessary for binding glutathione.
The Journal of biological chemistry 1992;267(26):18940-5.
1992: T H Manoharan; Andrew Gulick; Peter Reinemer; Heini W Dirr; Robert Huber; William E Fahl
Mutational substitution of residues implicated by crystal structure in binding the substrate glutathione to human glutathione S-transferase pi.
Journal of molecular biology 1992;226(2):319-22.
1991: T H Manoharan; P J Welch; Andrew Gulick; R B Puchalski; A L Lathrop; William E Fahl
Expression of tandem glutathione S-transferase recombinant genes in COS cells for analysis of efficiency of protein expression and associated drug resistance.
Molecular pharmacology 1991;39(4):461-7.