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Jeffrey Kordower

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V B Thompson; B T Terpstra; E Y Chen; James B Koprich; Jeffrey Kordower; Jack William Lipton
Prenatal exposure to MDMA alters noradrenergic neurodevelopment in the rat.
Timothy J Collier; Nicholas M Kanaan; Jeffrey Kordower
Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.
Raymond T Bartus; Christopher D Herzog; Yaping Chu; Alistair Wilson; Lamar Brown; Joao Siffert; Eugene M Johnson; C Warren Olanow; Elliott J Mufson; Jeffrey Kordower
Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains.

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All Publications

2012: V B Thompson; B T Terpstra; E Y Chen; James B Koprich; Jeffrey Kordower; Jack William Lipton
Prenatal exposure to MDMA alters noradrenergic neurodevelopment in the rat.
Neurotoxicology and teratology 2012;34(1):206-13.
2011: Timothy J Collier; Nicholas M Kanaan; Jeffrey Kordower
Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.
Nature reviews. Neuroscience 2011;12(6):359-66.
2011: Raymond T Bartus; Christopher D Herzog; Yaping Chu; Alistair Wilson; Lamar Brown; Joao Siffert; Eugene M Johnson; C Warren Olanow; Elliott J Mufson; Jeffrey Kordower
Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains.
Movement disorders : official journal of the Movement Disorder Society 2011;26(1):27-36.
2011: Dustin R Wakeman; Hemraj B Dodiya; Jeffrey Kordower
Cell transplantation and gene therapy in Parkinson's disease.
The Mount Sinai journal of medicine, New York 2011;78(1):126-58.
2011: Yaping Chu; Amanda L Mickiewicz; Jeffrey Kordower
α-synuclein aggregation reduces nigral myocyte enhancer factor-2D in idiopathic and experimental Parkinson's disease.
Neurobiology of disease 2011;41(1):71-82.
2011: David A Merrill; Eliezer Masliah; Jeffery A Roberts; Heather McKay; Jeffrey Kordower; Elliott J Mufson; Mark H Tuszynski
Association of early experience with neurodegeneration in aged primates.
Neurobiology of aging 2011;32(1):151-6.
2010: William J Marks; raymond bartus; Joao Siffert; Charles S Davis; Andres Lozano; Nicholas Boulis; Jerrold L Vitek; Mark Stacy; Dennis Turner; Leonard Verhagen; Roy A E Bakay; Ray L Watts; Barton Guthrie; Joseph Jankovic; Richard Simpson; Michele Tagliati; Ron Alterman; Matthew Stern; Gordon Baltuch; Philip A Starr; Paul S Larson; Jill L Ostrem; John G Nutt; Karl Kieburtz; Jeffrey Kordower; C Warren Olanow
Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial.
Lancet neurology 2010;9(12):1164-72.
2010: Yan Cai; Kun Xiong; Xue-Mei Zhang; Huaibin Cai; Xue-gang Luo; Jia-Chun Feng; Richard W Clough; Robert G Struble; Peter R Patrylo; Yaping Chu; Jeffrey Kordower; Xiao-Xin Yan
β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation.
The European journal of neuroscience 2010;32(7):1223-38.
2010: Jeffrey Kordower; Er-Yun Chen; John H Morrison
Long-term gonadal hormone treatment and endogenous neurogenesis in the dentate gyrus of the adult female monkey.
Experimental neurology 2010;224(1):252-7.
2010: Jose A Obeso; Maria C Rodriguez-Oroz; Christopher G Goetz; Concepcion Marin; Jeffrey Kordower; Manuel Rodriguez; Etienne C Hirsch; Matthew Farrer; Anthony H V Schapira; Glenda Halliday
Missing pieces in the Parkinson's disease puzzle.
Nature medicine 2010;16(6):653-61.
2010: Ina Han; YiMei You; Jeffrey Kordower; Scott T Brady; Gerardo Morfini
Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.
Journal of neurochemistry 2010;113(5):1073-91.
2010: Nicholas M Kanaan; Jeffrey Kordower; Timothy J Collier
Age-related changes in glial cells of dopamine midbrain subregions in rhesus monkeys.
Neurobiology of aging 2010;31(6):937-52.
2010: Hemraj B Dodiya; Tomas Bjorklund; James Stansell; Ronald J Mandel; Deniz Kirik; Jeffrey Kordower
Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(3):579-87.
2010: Suresh Babu Rangasamy; Katherine Soderstrom; Roy A E Bakay; Jeffrey Kordower
Neurotrophic factor therapy for Parkinson's disease.
Progress in brain research 2010;184():237-64.
2010: Tomas Bjorklund; Jeffrey Kordower
Gene therapy for Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2010;25 Suppl 1():S161-73.
2010: Yaping Chu; Jeffrey Kordower
Lewy body pathology in fetal grafts.
Annals of the New York Academy of Sciences 2010;1184():55-67.
2010: Dwaine F Emerich; David J Mooney; Hannah Storrie; Rangasamy Suresh Babu; Jeffrey Kordower
Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease.
Neurotoxicity research 2010;17(1):66-74.
2009: Shilpa Ramaswamy; Jeffrey Kordower
Are growth factors the answer?
Parkinsonism & related disorders 2009;15 Suppl 3():S176-80.
2009: Sally K Mak; Alison L McCormack; J William Langston; Jeffrey Kordower; Donato A Di Monte
Decreased alpha-synuclein expression in the aging mouse substantia nigra.
Experimental neurology 2009;220(2):359-65.
2009: Jeffrey Kordower; Patrik Brundin
Propagation of host disease to grafted neurons: accumulating evidence.
Experimental neurology 2009;220(2):224-5.
2009: C Warren Olanow; Jeffrey Kordower; Anthony E Lang; Jose A Obeso
Dopaminergic transplantation for Parkinson's disease: current status and future prospects.
Annals of neurology 2009;66(5):591-6.
2009: Marina E Emborg; Jeffrey Moirano; J Raschke; V Bondarenko; R Zufferey; S Peng; Allison D Ebert; V Joers; Ben Roitberg; James E Holden; J Koprich; Jack William Lipton; Jeffrey Kordower; Patrick Aebischer
Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF.
Neurobiology of disease 2009;36(2):303-11.
2009: C Warren Olanow; Jeffrey Kordower
Modeling Parkinson's disease.
Annals of neurology 2009;66(4):432-6.
2009: Jeffrey Kordower
Animal rights terrorists: what every neuroscientist should know.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(37):11419-20.
2009: Yaping Chu; Hemraj Dodiya; Patrick Aebischer; C Warren Olanow; Jeffrey Kordower
Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.
Neurobiology of disease 2009;35(3):385-98.
2009: Francesca Cicchetti; S Saporta; Robert A Hauser; Martin Parent; Martine Saint-Pierre; Paul Sanberg; Xiao-Jiang Li; J R Parker; Y Chu; Elliott J Mufson; Jeffrey Kordower; T B Freeman
Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(30):12483-8.
2009: John R Sladek; Paul Sanberg; Jeffrey Kordower
Celebrating neural repair.
The Journal of comparative neurology 2009;515(1):1-3.
2009: Christopher D Herzog; Lamar Brown; Dawn Gammon; Brian Kruegel; Richard Lin; Alistair Wilson; Ariadne Bolton; Marie Printz; Mehdi Gasmi; Kathie M Bishop; Jeffrey Kordower; raymond bartus
Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease.
Neurosurgery 2009;64(4):602-12; discussion 612-3.
2009: Yan Cai; Kun Xiong; Yaping Chu; Duan-Wu Luo; Xue-gang Luo; Xian-Yui Yuan; Robert G Struble; Richard W Clough; Dennis D Spencer; Anne Williamson; Jeffrey Kordower; Peter R Patrylo; Xiao-Xin Yan
Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups.
Experimental neurology 2009;216(2):342-56.
2009: Shilpa Ramaswamy; Jodi L McBride; Ina Han; Elizabeth M Berry-Kravis; Lili Zhou; Christopher D Herzog; Mehdi Gasmi; raymond bartus; Jeffrey Kordower
Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease.
Neurobiology of disease 2009;34(1):40-50.
2009: C Warren Olanow; Jean-Michel Gracies; Christopher G Goetz; A Jon Stoessl; Thomas Freeman; Jeffrey Kordower; James Godbold; Jose A Obeso
Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: a double blind video-based analysis.
Movement disorders : official journal of the Movement Disorder Society 2009;24(3):336-43.
2009: Xue-Mei Zhang; Yan Cai; Yaping Chu; Er-Yun Chen; Jia-Chun Feng; Xue-Gang Luo; Kun Xiong; Robert G Struble; Richard W Clough; Peter R Patrylo; Jeffrey Kordower; Xiao-Xin Yan
Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates.
Frontiers in neuroanatomy 2009;3():17.
2009: Shilpa Ramaswamy; Katherine E Soderstrom; Jeffrey Kordower
Trophic factors therapy in Parkinson's disease.
Progress in brain research 2009;175():201-16.
2009: Jeffrey Kordower; Patrik Brundin
Lewy body pathology in long-term fetal nigral transplants: is Parkinson's disease transmitted from one neural system to another?
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(1):254.
2008: Jeffrey Kordower; Yaping Chu; Robert A Hauser; C Warren Olanow; Thomas B Freeman
Transplanted dopaminergic neurons develop PD pathologic changes: a second case report.
Movement disorders : official journal of the Movement Disorder Society 2008;23(16):2303-6.
2008: Ole Isacson; Jeffrey Kordower
Future of cell and gene therapies for Parkinson's disease.
Annals of neurology 2008;64 Suppl 2():S122-38.
2008: Christopher D Herzog; Biplob Dass; Mehdi Gasmi; Roy A E Bakay; James E Stansell; Mark H Tuszynski; Krystof Bankiewicz; Er-Yun Chen; Yaping Chu; Kathie Bishop; Jeffrey Kordower; raymond bartus
Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(10):1737-44.
2008: Nicholas M Kanaan; Jeffrey Kordower; Timothy J Collier
Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys.
Glia 2008;56(11):1199-214.
2008: Nicholas M Kanaan; Jeffrey Kordower; Timothy J Collier
Age-related changes in dopamine transporters and accumulation of 3-nitrotyrosine in rhesus monkey midbrain dopamine neurons: relevance in selective neuronal vulnerability to degeneration.
The European journal of neuroscience 2008;27(12):3205-15.
2008: Jeffrey Kordower; Yaping Chu; Robert A Hauser; Thomas B Freeman; C Warren Olanow
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease.
Nature medicine 2008;14(5):504-6.
2008: Julie G Pilitsis; Yaping Chu; Jeffrey Kordower; Donna C Bergen; Elizabeth J Cochran; Roy A E Bakay
Postmortem study of deep brain stimulation of the anterior thalamus: case report.
Neurosurgery 2008;62(2):E530-2; discussion E532.
2008: Jeffrey Kordower
Introduction to the special ASNTR issue.
Cell transplantation 2008;17(4):361-2.
2008: D E Redmond; A Vinuela; Jeffrey Kordower; Ole Isacson
Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson's disease.
Neurobiology of disease 2008;29(1):103-16.
2008: Jeffrey Kordower; C Warren Olanow
Regulatable promoters and gene therapy for Parkinson's disease: is the only thing to fear, fear itself?
Experimental neurology 2008;209(1):34-40.
2007: Anamitra Ghosh; Avik Roy; Xiaojuan Liu; Jeffrey Kordower; Elliott J Mufson; Dean Hartley; Sankar Ghosh; R Lee Mosley; Howard E Gendelman; Kalipada Pahan
Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(47):18754-9.
2007: Sepehr Sani; Kirk W Jobe; Adam Smith; Jeffrey Kordower; Roy A E Bakay
Deep brain stimulation for treatment of obesity in rats.
Journal of neurosurgery 2007;107(4):809-13.
2007: Katie Kompoliti; Yaping Chu; Kathleen M Shannon; Jeffrey Kordower
Neuropathological study 16 years after autologous adrenal medullary transplantation in a Parkinson's disease patient.
Movement disorders : official journal of the Movement Disorder Society 2007;22(11):1630-3.
2007: Mehdi Gasmi; Eugene Brandon; Christopher D Herzog; Alistair Wilson; Kathie M Bishop; Eva K Hofer; Justine J Cunningham; Marie A Printz; Jeffrey Kordower; raymond bartus
AAV2-mediated delivery of human neurturin to the rat nigrostriatal system: long-term efficacy and tolerability of CERE-120 for Parkinson's disease.
Neurobiology of disease 2007;27(1):67-76.
2007: Christopher D Herzog; Biplob Dass; James E Holden; James Stansell; Mehdi Gasmi; Mark H Tuszynski; raymond bartus; Jeffrey Kordower
Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys.
Movement disorders : official journal of the Movement Disorder Society 2007;22(8):1124-32.
2007: Nicholas M Kanaan; Jeffrey Kordower; Timothy J Collier
Age-related accumulation of Marinesco bodies and lipofuscin in rhesus monkey midbrain dopamine neurons: relevance to selective neuronal vulnerability.
The Journal of comparative neurology 2007;502(5):683-700.
2007: Deanna M Marchionini; Elin Lehrmann; Yaping Chu; Bin He; Caryl E Sortwell; Kevin G Becker; William J Freed; Jeffrey Kordower; Timothy J Collier
Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease.
Brain research 2007;1147():77-88.
2007: Shilpa Ramaswamy; Jodi L McBride; Christopher D Herzog; Eugene Brandon; Mehdi Gasmi; raymond bartus; Jeffrey Kordower
Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease.
Neurobiology of disease 2007;26(2):375-84.
2007: Timothy J Collier; Jack William Lipton; Brian F Daley; Stéphane Palfi; Yaping Chu; Caryl E Sortwell; Roy A E Bakay; John R Sladek; Jeffrey Kordower
Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism.
Neurobiology of disease 2007;26(1):56-65.
2007: Biplob Dass; Jeffrey Kordower
Gene therapy approaches for the treatment of Parkinson's disease.
Handbook of clinical neurology 2007;84():291-304.
2007: raymond bartus; Christopher D Herzog; Kathie Bishop; Jeffrey M Ostrove; Mark H Tuszynski; Jeffrey Kordower; Mehdi Gasmi
Issues regarding gene therapy products for Parkinson's disease: the development of CERE-120 (AAV-NTN) as one reference point.
Parkinsonism & related disorders 2007;13 Suppl 3():S469-77.
2007: Shilpa Ramaswamy; Jodi L McBride; Jeffrey Kordower
Animal models of Huntington's disease.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2007;48(4):356-73.
2007: Shilpa Ramaswamy; Kathleen M Shannon; Jeffrey Kordower
Huntington's disease: pathological mechanisms and therapeutic strategies.
Cell transplantation 2007;16(3):301-12.
2007: Yaping Chu; Jeffrey Kordower
Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
Neurobiology of disease 2007;25(1):134-49.
2006: Jeffrey Kordower; Christopher D Herzog; Biplob Dass; Roy A E Bakay; James Stansell; Mehdi Gasmi; raymond bartus
Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys.
Annals of neurology 2006;60(6):706-15.
2006: Jordi Bové; Chun Zhou; Vernice Jackson-Lewis; Julie Taylor; Yaping Chu; Hardy J Rideout; Du-Chu Wu; Jeffrey Kordower; Leonard Petrucelli; Serge Przedborski
Proteasome inhibition and Parkinson's disease modeling.
Annals of neurology 2006;60(2):260-4.
2006: Jeffrey Kordower; Nicholas M Kanaan; Yaping Chu; Rangasamy Suresh Babu; James Stansell; Brian T Terpstra; Caryl E Sortwell; Kathy Steece-Collier; Timothy J Collier
Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.
Annals of neurology 2006;60(2):264-8.
2006: Dwaine F Emerich; Christopher G Thanos; Moses Goddard; Stephen J M Skinner; Marilyn S Geany; William J Bell; Briannan Bintz; Patricia Schneider; Yaping Chu; Rangasamy Suresh Babu; Cesario Borlongan; Kim Boekelheide; Susan Hall; Bronwyn Bryant; Jeffrey Kordower
Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys.
Neurobiology of disease 2006;23(2):471-80.
2006: Marina E Emborg; Jeffrey Moirano; K T Schafernak; M Moirano; M Evans; T Konecny; Ben Roitberg; P Ambarish; E Mangubat; Y Ma; David Eidelberg; J Holden; Jeffrey Kordower; J E Leestma
Basal ganglia lesions after MPTP administration in rhesus monkeys.
Neurobiology of disease 2006;23(2):281-9.
2006: Ben Roitberg; Erwin Mangubat; Er-Yun Chen; Kiminobu Sugaya; Keith R Thulborn; Jeffrey Kordower; Ambarish Pawar; Todd Konecny; Marina E Emborg
Survival and early differentiation of human neural stem cells transplanted in a nonhuman primate model of stroke.
Journal of neurosurgery 2006;105(1):96-102.
2006: Jodi L McBride; Shilpa Ramaswamy; Mehdi Gasmi; raymond bartus; Christopher D Herzog; Eugene Brandon; Lili Zhou; Mark R Pitzer; Elizabeth M Berry-Kravis; Jeffrey Kordower
Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9345-50.
2006: Biplob Dass; Theodora Kladis; Yaping Chu; Jeffrey Kordower
RET expression does not change with age in the substantia nigra pars compacta of rhesus monkeys.
Neurobiology of aging 2006;27(6):857-61.
2006: Biplob Dass; C Warren Olanow; Jeffrey Kordower
Gene transfer of trophic factors and stem cell grafting as treatments for Parkinson's disease.
Neurology 2006;66(10 Suppl 4):S89-103.
2006: Soshana Behrstock; Allison D Ebert; Jacalyn McHugh; S Vosberg; J Moore; B Schneider; Elizabeth E Capowski; D Hei; Jeffrey Kordower; Patrick Aebischer; Clive Svendsen
Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates.
Gene therapy 2006;13(5):379-88.
2006: Robert A Rissman; Romy Nocera; Laura M Fuller; Jeffrey Kordower; David M Armstrong
Age-related alterations in GABA(A) receptor subunits in the nonhuman primate hippocampus.
Brain research 2006;1073-1074():120-30.
2006: Yaping Chu; Weidong Le; Katie Kompoliti; Joseph Jankovic; Elliott J Mufson; Jeffrey Kordower
Nurr1 in Parkinson's disease and related disorders.
The Journal of comparative neurology 2006;494(3):495-514.
2006: Katherine Soderstrom; Jennifer O'Malley; Kathy Steece-Collier; Jeffrey Kordower
Neural repair strategies for Parkinson's disease: insights from primate models.
Cell transplantation 2006;15(3):251-65.
2006: Julie A Schneider; Jia-liang Li; Yan Li; Robert S Wilson; Jeffrey Kordower; David A Bennett
Substantia nigra tangles are related to gait impairment in older persons.
Annals of neurology 2006;59(1):166-73.
2006: Eleonora Maries; Jeffrey Kordower; Yaping Chu; Timothy J Collier; Caryl E Sortwell; Eliza Olaru; Kathleen Shannon; Kathy Steece-Collier
Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats.
Neurobiology of disease 2006;21(1):165-80.
2005: Scott E Counts; Er-Yun Chen; Stephen D. Ginsberg; Jeffrey Kordower; Elliott J Mufson
RNA amplification of bromodeoxyuridine labeled newborn neurons in the monkey hippocampus.
Journal of neuroscience methods 2005;144(2):197-201.
2005: Mark H Tuszynski; Leon J Thal; Mary Pay; David P Salmon; Hoi Sang U; Roy A E Bakay; Piyush Patel; Armin Blesch; H Lee Vahlsing; Gilbert Ho; Gang Tong; Steven G Potkin; James Fallon; Lawrence A Hansen; Elliott J Mufson; Jeffrey Kordower; Christine M Gall; James Conner
A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease.
Nature medicine 2005;11(5):551-5.
2005: Timothy J Collier; Zao Dung Ling; Paul Carvey; Anita Fletcher-Turner; David M Yurek; John R Sladek; Jeffrey Kordower
Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism.
Experimental neurology 2005;191 Suppl 1():S60-7.
2004: Sylvia Perez; TJ Sendera; Jeffrey Kordower; Elliott J Mufson
Estrogen receptor alpha containing neurons in the monkey forebrain: lack of association with calcium binding proteins and choline acetyltransferase.
Brain research 2004;1019(1-2):55-63.
2004: Nicholas A DiProspero; Er-Yun Chen; Vinod Charles; Markus Plomann; Jeffrey Kordower; Danilo A Tagle
Early changes in Huntington's disease patient brains involve alterations in cytoskeletal and synaptic elements.
Journal of neurocytology 2004;33(5):517-33.
2004: Jodi L McBride; Soshana Behrstock; Er-Yun Chen; Rebekah J Jakel; Irwin Siegel; Clive Svendsen; Jeffrey Kordower
Human neural stem cell transplants improve motor function in a rat model of Huntington's disease.
The Journal of comparative neurology 2004;475(2):211-9.
2004: Katie Kompoliti; Yaping Chu; Ari Polish; Jeffrey Roberts; Heather McKay; Elliott J Mufson; Sue Leurgans; John H Morrison; Jeffrey Kordower
Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys.
The Journal of comparative neurology 2004;472(2):193-207.
2004: Yong Tang; william janssen; Jiandong Hao; Jeffrey A Roberts; Heather McKay; Bill Lasley; Patrick B Allen; Paul Greengard; Peter R Rapp; Jeffrey Kordower; Patrick R Hof; John H Morrison
Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys.
Cerebral cortex (New York, N.Y. : 1991) 2004;14(2):215-23.
2003: Jiandong Hao; william janssen; Yong Tang; Jeffrey A Roberts; Heather McKay; Bill Lasley; Patrick B Allen; Paul Greengard; Peter R Rapp; Jeffrey Kordower; Patrick R Hof; John H Morrison
Estrogen increases the number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys.
The Journal of comparative neurology 2003;465(4):540-50.
2003: Timothy J Collier; Kathy Steece-Collier; Jeffrey Kordower
Primate models of Parkinson's disease.
Experimental neurology 2003;183(2):258-62.
2003: James B Koprich; Er-Yun Chen; Nicholas M Kanaan; Nicholas G Campbell; Jeffrey Kordower; Jack William Lipton
Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) alters exploratory behavior, reduces monoamine metabolism, and increases forebrain tyrosine hydroxylase fiber density of juvenile rats.
Neurotoxicology and teratology 2003;25(5):509-17.
2003: C Warren Olanow; Christopher G Goetz; Jeffrey Kordower; A Jon Stoessl; Vesna Sossi; Mitchell F Brin; Kathleen M Shannon; G Michael Nauert; Daniel P Perl; James Godbold; Thomas B Freeman
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease.
Annals of neurology 2003;54(3):403-14.
2003: Eleonora Maries; Biplob Dass; Timothy J Collier; Jeffrey Kordower; Kathy Steece-Collier
The role of alpha-synuclein in Parkinson's disease: insights from animal models.
Nature reviews. Neuroscience 2003;4(9):727-38.
2003: Laura Kus; Ewa Borys; Ya Ping Chu; Shawn M Ferguson; Randy D Blakely; Marina E Emborg; Jeffrey Kordower; Allan Levey; Elliott J Mufson
Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system.
The Journal of comparative neurology 2003;463(3):341-57.
2003: Heather C Salzberg-Brenhouse; Er-Yun Chen; Dwaine F Emerich; Sam Baldwin; Ken Hogeland; Sharon Ranelli; Denise Lafreniere; Brigido Perdomo; Leah Novak; Theodora Kladis; Karen Fu; Anthony Basile; Jeffrey Kordower; raymond bartus
Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration.
The Journal of pharmacology and experimental therapeutics 2003;306(1):218-28.
2003: Rose Hanbury; Zao Dung Ling; Joanne Wuu; Jeffrey Kordower
GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults.
The Journal of comparative neurology 2003;461(3):307-16.
2003: Jodi L McBride; Matthew J During; Joanne Wuu; Er-Yun Chen; Sue Leurgans; Jeffrey Kordower
Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF.
Experimental neurology 2003;181(2):213-23.
2003: Rose Hanbury; Er-Yun Chen; Joanne Wuu; Jeffrey Kordower
Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury.
Journal of molecular neuroscience : MN 2003;20(2):93-102.
2003: Jeffrey Kordower
In vivo gene delivery of glial cell line--derived neurotrophic factor for Parkinson's disease.
Annals of neurology 2003;53 Suppl 3():S120-32; discussion S132-4.
2003: Ben Roitberg; Naimath Khan; Eray Tuccar; Katie Kompoliti; Yaping Chu; Noam Alperin; Jeffrey Kordower; Marina E Emborg
Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study.
Neurological research 2003;25(1):68-78.
2002: Jamie L Eberling; Phillip Pivirotto; John Bringas; Joseph P Steiner; Jeffrey Kordower; Yaping Chu; Marina E Emborg; Krystof S Bankiewicz
The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys.
Experimental neurology 2002;178(2):236-42.
2002: Kathy Steece-Collier; Eleonora Maries; Jeffrey Kordower
Etiology of Parkinson's disease: Genetics and environment revisited.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):13972-4.
2002: Yaping Chu; Katie Kompoliti; Elizabeth J Cochran; Elliott J Mufson; Jeffrey Kordower
Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra.
The Journal of comparative neurology 2002;450(3):203-14.
2002: Stéphane Palfi; Liza Leventhal; Yaping Chu; Shuang Y Ma; Marina E Emborg; Roy A E Bakay; Nicole Deglon; Philippe Hantraye; Patrick Aebischer; Jeffrey Kordower
Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(12):4942-54.
2002: Rose Hanbury; Vinod Charles; Er-Yun Chen; Liza Leventhal; Jeffrey M Rosenstein; Elliott J Mufson; Jeffrey Kordower
Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors.
The Journal of comparative neurology 2002;444(4):291-305.
2002: Elliott J Mufson; Shuang Y Ma; John Dills; Elizabeth J Cochran; Sue Leurgans; Joanne Wuu; David A Bennett; Syed Jaffar; Michelle L Gilmor; Allan Levey; Jeffrey Kordower
Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease.
The Journal of comparative neurology 2002;443(2):136-53.
2002: Steven T DeKosky; Milos D Ikonomovic; Scot D Styren; Laurel Beckett; Stephen R Wisniewski; David A Bennett; Elizabeth J Cochran; Jeffrey Kordower; Elliott J Mufson
Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.
Annals of neurology 2002;51(2):145-55.
2002: Jodi L McBride; Jeffrey Kordower
Neuroprotection for Parkinson's disease using viral vector-mediated delivery of GDNF.
Progress in brain research 2002;138():421-32.
2002: Ben Roitberg; Marina E Emborg; Joseph G Sramek; Stéphane Palfi; Jeffrey Kordower
Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease.
Neurosurgery 2002;50(1):137-45; discussion 145-6.
2001: Y Chu; E J Cochran; David A Bennett; Elliott J Mufson; Jeffrey Kordower
Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease.
The Journal of comparative neurology 2001;437(3):296-307.
2001: C Warren Olanow; T Freeman; Jeffrey Kordower
Transplantation of embryonic dopamine neurons for severe Parkinson's disease.
The New England journal of medicine 2001;345(2):146; author reply 147.
2001: Paolo Guidetti; Vinod Charles; Er-Yun Chen; P Hemachandra Reddy; Jeffrey Kordower; William O Whetsell; Robert Schwarcz; Danilo A Tagle
Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production.
Experimental neurology 2001;169(2):340-50.
2001: Jeffrey Kordower; P Aebischer
Gene therapy to the rescue in Parkinson's disease. Response from Kordower and Aebischer.
Trends in pharmacological sciences 2001;22(3):105-6.
2001: Marina E Emborg; P Shin; Ben Roitberg; Joseph G Sramek; Y Chu; Glenn T Stebbins; J S Hamilton; PD Suzdak; Joseph P Steiner; Jeffrey Kordower
Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys.
Experimental neurology 2001;168(1):171-82.
2001: Jeffrey Kordower; Y Chu; Glenn T Stebbins; Steven T DeKosky; E J Cochran; David A Bennett; Elliott J Mufson
Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment.
Annals of neurology 2001;49(2):202-13.
2000: Thomas B Freeman; F Cicchetti; Robert A Hauser; TW Deacon; Xiao-Jiang Li; Steven M Hersch; G Michael Nauert; Paul Sanberg; Jeffrey Kordower; Samuel Saporta; Ole Isacson
Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13877-82.
2000: EV Gurevich; Jeffrey Kordower; Jeffrey N. Joyce
Ontogeny of the dopamine D2 receptor mRNA expressing cells in the human hippocampal formation and temporal neocortex.
Journal of chemical neuroanatomy 2000;20(3-4):307-25.
2000: Elliott J Mufson; Shuang Y Ma; E J Cochran; David A Bennett; Laurel Beckett; Syed Jaffar; H Uri Saragovi; Jeffrey Kordower
Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease.
The Journal of comparative neurology 2000;427(1):19-30.
2000: Er-Yun Chen; DF Emerich; raymond bartus; Jeffrey Kordower
B2 bradykinin receptor immunoreactivity in rat brain.
The Journal of comparative neurology 2000;427(1):1-18.
2000: Er-Yun Chen; Eric R Kallwitz; SE Leff; E J Cochran; Elliott J Mufson; Jeffrey Kordower; Ronald J Mandel
Age-related decreases in GTP-cyclohydrolase-I immunoreactive neurons in the monkey and human substantia nigra.
The Journal of comparative neurology 2000;426(4):534-48.
2000: Jeffrey Kordower; Marina E Emborg; J Bloch; Shuang Y Ma; Yaping Chu; Liza Leventhal; J McBride; Er-Yun Chen; Stéphane Palfi; Ben Roitberg; WD Brown; James E Holden; Robert W Pyzalski; MD Taylor; Paul Carvey; Z Ling; D Trono; Philippe Hantraye; Nicole Deglon; Patrick Aebischer
Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.
Science (New York, N.Y.) 2000;290(5492):767-73.
2000: Liza Leventhal; Caryl E Sortwell; Rose Hanbury; Timothy J Collier; Jeffrey Kordower; Stéphane Palfi
Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity.
The Journal of comparative neurology 2000;425(4):471-8.
2000: Jeffrey Kordower
Making the counts count: the stereology revolution.
Journal of chemical neuroanatomy 2000;20(1):1-2.
2000: Stéphane Palfi; Liza Leventhal; Christopher G Goetz; T Hantraye; Ben Roitberg; Joseph G Sramek; Marina E Emborg; Jeffrey Kordower
Delayed onset of progressive dystonia following subacute 3-nitropropionic acid treatment in Cebus apella monkeys.
Movement disorders : official journal of the Movement Disorder Society 2000;15(3):524-30.
2000: TJ Sendera; Shuang Y Ma; Syed Jaffar; P B Kozlowski; Jeffrey Kordower; Yogesh Mawal; H Uri Saragovi; Elliott J Mufson
Reduction in TrkA-immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome.
Journal of neurochemistry 2000;74(3):1185-96.
2000: Jeffrey Kordower; Ole Isacson; Liza Leventhal; DF Emerich
Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?
Progress in brain research 2000;127():414-30.
2000: Jeffrey Kordower; Caryl E Sortwell
Neuropathology of fetal nigra transplants for Parkinson's disease.
Progress in brain research 2000;127():333-44.
2000: Marina E Emborg; Jeffrey Kordower
Delivery of therapeutic molecules into the CNS.
Progress in brain research 2000;128():323-32.
2000: raymond bartus; Pamela Snodgrass; Reginald L Dean; Jeffrey Kordower; Dwaine F Emerich
Evidence that Cereport's ability to increase permeability of rat gliomas is dependent upon extent of tumor growth: implications for treating newly emerging tumor colonies.
Experimental neurology 2000;161(1):234-44.
1999: Elliott J Mufson; W J Cai; Syed Jaffar; E Chen; Glenn T Stebbins; TJ Sendera; Jeffrey Kordower
Estrogen receptor immunoreactivity within subregions of the rat forebrain: neuronal distribution and association with perikarya containing choline acetyltransferase.
Brain research 1999;849(1-2):253-74.
1999: Jeffrey Kordower; Christopher G Goetz
The first miracle in neurodegenerative disease: the discovery of oral levodopa.
Brain research bulletin 1999;50(5-6):377-8.
1999: Jeffrey Kordower; J Bloch; Shuang Y Ma; Yaping Chu; Stéphane Palfi; Ben Roitberg; Marina E Emborg; Philippe Hantraye; Nicole Deglon; Patrick Aebischer
Lentiviral gene transfer to the nonhuman primate brain.
Experimental neurology 1999;160(1):1-16.
1999: Jeffrey Kordower; Ole Isacson; DF Emerich
Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?
Experimental neurology 1999;159(1):4-20.
1999: Jeffrey Kordower; Stéphane Palfi; Er-Yun Chen; Shuang Y Ma; TJ Sendera; E J Cochran; E J Cochran; Elliott J Mufson; R Penn; Christopher G Goetz; C D Comella
Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease.
Annals of neurology 1999;46(3):419-24.
1999: Elliott J Mufson; E Y Chen; E J Cochran; Laurel Beckett; David A Bennett; Jeffrey Kordower
Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment.
Experimental neurology 1999;158(2):469-90.
1999: Shuang Y Ma; Brian Ciliax; Glenn T Stebbins; Syed Jaffar; Jeffrey N. Joyce; Elizabeth J Cochran; Jeffrey Kordower; Deborah C Mash; Allan Levey; Elliott J Mufson
Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra.
The Journal of comparative neurology 1999;409(1):25-37.
1999: raymond bartus; E Y Chen; G Lynch; Jeffrey Kordower
Cortical ablation induces a spreading calcium-dependent, secondary pathogenesis which can be reduced by inhibiting calpain.
Experimental neurology 1999;155(2):315-26.
1999: Robert A Hauser; Thomas B Freeman; B J Snow; M Nauert; LL Gauger; Jeffrey Kordower; C Warren Olanow
Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease.
Archives of neurology 1999;56(2):179-87.
1998: Elliott J Mufson; U Kahl; R Bowser; Deborah C Mash; Jeffrey Kordower; Darlene C Deecher
Galanin expression within the basal forebrain in Alzheimer's disease. Comments on therapeutic potential.
Annals of the New York Academy of Sciences 1998;863():291-304.
1998: Marina E Emborg; Shuang Y Ma; Elliott J Mufson; Allan Levey; MD Taylor; WD Brown; James E Holden; Jeffrey Kordower
Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys.
The Journal of comparative neurology 1998;401(2):253-65.
1998: Jeffrey Kordower; TB Freeman; Er-Yun Chen; Elliott J Mufson; Paul Sanberg; Robert A Hauser; B Snow; C Warren Olanow
Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1998;13(3):383-93.
1998: DF Emerich; S Bruhn; Y Chu; Jeffrey Kordower
Cellular delivery of CNTF but not NT-4/5 prevents degeneration of striatal neurons in a rodent model of Huntington's disease.
Cell transplantation 1998;7(2):213-25.
1998: Ann-Charlotte E. Granholm-Bentley; David S Albeck; Cristina Bäckman; M Curtis; Ted Ebendal; Phillip Friden; Michael Henry; Barry Hoffer; Jeffrey Kordower; Gregory M Rose; Stine Söderström; raymond bartus
A non-invasive system for delivering neural growth factors across the blood-brain barrier: a review.
Reviews in the neurosciences 1998;9(1):31-55.
1998: Jeffrey Kordower; TB Freeman; C Warren Olanow
Neuropathology of fetal nigral grafts in patients with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1998;13 Suppl 1():88-95.
1997: EV Gurevich; Jeffrey Kordower; Jeffrey N. Joyce
Dopamine D2 receptor mRNA is expressed in maturing neurons of the human hippocampal and subicular fields.
Neuroreport 1997;8(16):3605-10.
1997: MK Carpenter; Christian Winkler; RA Fricker; DF Emerich; S C Wong; C Greco; Er-Yun Chen; Y Chu; Jeffrey Kordower; A Messing; Anders Björklund; JP Hammang
Generation and transplantation of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice.
Experimental neurology 1997;148(1):187-204.
1997: Jeffrey Kordower; Er-Yun Chen; C Winkler; RA Fricker; Vinod Charles; A Messing; Elliott J Mufson; S C Wong; J M Rosenstein; Anders Björklund; DF Emerich; JP Hammang; MK Carpenter
Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease.
The Journal of comparative neurology 1997;387(1):96-113.
1997: Ray L Watts; Thyagarajan Subramanian; Alan Freeman; Christopher G Goetz; Richard D Penn; Glenn T Stebbins; Jeffrey Kordower; Roy A E Bakay
Effect of stereotaxic intrastriatal cografts of autologous adrenal medulla and peripheral nerve in Parkinson's disease: two-year follow-up study.
Experimental neurology 1997;147(2):510-7.
1997: C Lim; Elliott J Mufson; Jeffrey Kordower; H W Blume; J R Madsen; Clifford B Saper
Connections of the hippocampal formation in humans: II. The endfolial fiber pathway.
The Journal of comparative neurology 1997;385(3):352-71.
1997: Elliott J Mufson; Natalie Lavine; Syed Jaffar; Jeffrey Kordower; R Quirion; H Uri Saragovi
Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease.
Experimental neurology 1997;146(1):91-103.
1997: Jeffrey Kordower; Elliott J Mufson; N Fox; L Martel; DF Emerich
Cellular delivery of NGF does not alter the expression of beta-amyloid immunoreactivity in young or aged nonhuman primates.
Experimental neurology 1997;145(2 Pt 1):586-91.
1997: Jeffrey Kordower; T B Freeman; Roy A E Bakay; Christopher G Goetz; C Warren Olanow
Treatment with fetal allografts.
Neurology 1997;48(6):1737-8.
1997: Jeffrey Kordower; Scot D Styren; M Clarke; Steven T DeKosky; C Warren Olanow; TB Freeman
Fetal grafting for Parkinson's disease: expression of immune markers in two patients with functional fetal nigral implants.
Cell transplantation 1997;6(3):213-9.
1997: Mara Bresjanac; Jacqueline Sagen; G Seigel; C L Paino; Jeffrey Kordower; D M Gash
Xenogeneic adrenal medulla graft rejection rather than survival leads to increased rat striatal tyrosine hydroxylase immunoreactivity.
Journal of neuropathology and experimental neurology 1997;56(5):490-8.
1997: Robert Bowser; Jeffrey Kordower; Elliott J Mufson
A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer's disease.
Brain pathology (Zurich, Switzerland) 1997;7(2):723-30.
1997: D F Emerich; Shelley R Winn; Philippe Hantraye; Marc Peschanski; E Y Chen; Y Chu; P McDermott; E E Baetge; Jeffrey Kordower
Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease.
Nature 1997;386(6623):395-9.
1997: Jeffrey Kordower; Christopher G Goetz; T B Freeman; C Warren Olanow
Dopaminergic transplants in patients with Parkinson's disease: neuroanatomical correlates of clinical recovery.
Experimental neurology 1997;144(1):41-6.
1997: Jeffrey Kordower; A J Maclennan
Ciliary neurotrophic factor receptor alpha-immunoreactivity in the monkey central nervous system.
The Journal of comparative neurology 1997;377(3):365-80.
1997: C Warren Olanow; T B Freeman; Jeffrey Kordower
Neural transplantation as a therapy for Parkinson's disease.
Advances in neurology 1997;74():249-69.
1996: Elliott J Mufson; J M Li; T Sobreviela; Jeffrey Kordower
Decreased trkA gene expression within basal forebrain neurons in Alzheimer's disease.
Neuroreport 1996;8(1):25-9.
1996: D F Emerich; Mark D Lindner; Shelley R Winn; E Y Chen; B R Frydel; Jeffrey Kordower
Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(16):5168-81.
1996: V Charles; Elliott J Mufson; Phillip Friden; raymond bartus; Jeffrey Kordower
Atrophy of cholinergic basal forebrain neurons following excitotoxic cortical lesions is reversed by intravenous administration of an NGF conjugate.
Brain research 1996;728(2):193-203.
1996: Jeffrey Kordower; J M Rosenstein; Timothy J Collier; M A Burke; E Y Chen; J M Li; L Martel; A E Levey; Elliott J Mufson; T B Freeman; C Warren Olanow
Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies.
The Journal of comparative neurology 1996;370(2):203-30.
1996: E Y Chen; Elliott J Mufson; Jeffrey Kordower
TRK and p75 neurotrophin receptor systems in the developing human brain.
The Journal of comparative neurology 1996;369(4):591-618.
1996: Jeffrey Kordower; E Y Chen; Elliott J Mufson; Shelley R Winn; D F Emerich
Intrastriatal implants of polymer encapsulated cells genetically modified to secrete human nerve growth factor: trophic effects upon cholinergic and noncholinergic striatal neurons.
Neuroscience 1996;72(1):63-77.
1996: Adam Gazzaley; Steven J Siegel; Jeffrey Kordower; Elliott J Mufson; John H Morrison
Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):3121-5.
1996: C Warren Olanow; Jeffrey Kordower; T B Freeman
Fetal nigral transplantation as a therapy for Parkinson's disease.
Trends in neurosciences 1996;19(3):102-9.
1996: Elliott J Mufson; J S Kroin; Y T Liu; T Sobreviela; R D Penn; J A Miller; Jeffrey Kordower
Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: distribution, retrograde transport and co-localization with substantia nigra dopamine-containing neurons.
Neuroscience 1996;71(1):179-91.
1996: K M Shannon; Jeffrey Kordower
Neural transplantation for Huntington's disease: experimental rationale and recommendations for clinical trials.
Cell transplantation 1996;5(2):339-52.
1996: R T Bartus; R L Dean; S Abelleira; V Charles; Jeffrey Kordower
Dissociation of p75 receptors and nerve growth factor neurotrophic effects: lack of p75 immunoreactivity in striatum following physical trauma, excitotoxicity and NGF administration.
Restorative neurology and neuroscience 1996;10(1):49-59.
1995: T B Freeman; C Warren Olanow; Robert A Hauser; G M Nauert; D A Smith; Cesario Borlongan; Paul Sanberg; D A Holt; Jeffrey Kordower; FJ Vingerhoets
Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease.
Annals of neurology 1995;38(3):379-88.
1995: Elliott J Mufson; J M Conner; Jeffrey Kordower
Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis.
Neuroreport 1995;6(7):1063-6.
1995: Jeffrey Kordower; T B Freeman; BJ Snow; FJ Vingerhoets; Elliott J Mufson; Paul Sanberg; Robert A Hauser; D A Smith; G M Nauert; Daniel P Perl
Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease.
The New England journal of medicine 1995;332(17):1118-24.
1995: Jeffrey Kordower; Y T Liu; Shelley R Winn; D F Emerich
Encapsulated PC12 cell transplants into hemiparkinsonian monkeys: a behavioral, neuroanatomical, and neurochemical analysis.
Cell transplantation 1995;4(2):155-71.
1995: Elliott J Mufson; W C Benzing; Jeffrey Kordower
Dissociation of galaninergic and neurotrophic plasticity in Down syndrome and Alzheimer disease.
Progress in clinical and biological research 1995;393():105-22.
1995: J P Hammang; D F Emerich; Shelley R Winn; A Lee; Mark D Lindner; F T Gentile; E J Doherty; Jeffrey Kordower; E E Baetge
Delivery of neurotrophic factors to the CNS using encapsulated cells: developing treatments for neurodegenerative diseases.
Cell transplantation 1995;4 Suppl 1():S27-8.
1995: S B Schueler; Jacqueline Sagen; George D Pappas; Jeffrey Kordower
Long-term viability of isolated bovine adrenal medullary chromaffin cells following intrastriatal transplantation.
Cell transplantation 1995;4(1):55-64.
1995: R Anton; Jeffrey Kordower; D J Kane; C H Markham; Dale E Bredesen
Neural transplantation of cells expressing the anti-apoptotic gene bcl-2.
Cell transplantation 1995;4(1):49-54.
1995: T B Freeman; Paul Sanberg; G M Nauert; B D Boss; D Spector; C Warren Olanow; Jeffrey Kordower
The influence of donor age on the survival of solid and suspension intraparenchymal human embryonic nigral grafts.
Cell transplantation 1995;4(1):141-54.
1994: T Sobreviela; D O Clary; Louis F Reichardt; M M Brandabur; Jeffrey Kordower; Elliott J Mufson
TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin.
The Journal of comparative neurology 1994;350(4):587-611.
1994: M A Burke; William C. Mobley; J Cho; S J Wiegand; Ronald Lindsay; Elliott J Mufson; Jeffrey Kordower
Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins.
Experimental neurology 1994;130(2):178-95.
1994: Jeffrey Kordower; Shelley R Winn; Y T Liu; Elliott J Mufson; J R Sladek; J P Hammang; E E Baetge; D F Emerich
The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10898-902.
1994: Jeffrey Kordower; E Y Chen; J R Sladek; Elliott J Mufson
trk-immunoreactivity in the monkey central nervous system: forebrain.
The Journal of comparative neurology 1994;349(1):20-35.
1994: D F Emerich; Shelley R Winn; J Harper; J P Hammang; E E Baetge; Jeffrey Kordower
Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons.
The Journal of comparative neurology 1994;349(1):148-64.
1994: Jeffrey Kordower; V Charles; R Bayer; raymond bartus; S Putney; L R Walus; Phillip Friden
Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):9077-80.
1994: Elliott J Mufson; W C Benzing; Gregory M. Cole; H Wang; D F Emerich; J R Sladek; J H Morrison; Jeffrey Kordower
Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: colocalization with amyloid plaques.
Neurobiology of aging 1994;15(5):621-7.
1994: Elliott J Mufson; J S Kroin; T Sobreviela; M A Burke; Jeffrey Kordower; R D Penn; J A Miller
Intrastriatal infusions of brain-derived neurotrophic factor: retrograde transport and colocalization with dopamine containing substantia nigra neurons in rat.
Experimental neurology 1994;129(1):15-26.
1994: M A Burke; J R Apter; B H Wainer; Elliott J Mufson; Jeffrey Kordower
Age-related vulnerability of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus.
Experimental neurology 1994;128(2):159-71.
1994: R Anton; Jeffrey Kordower; Nigel T Maidment; J S Manaster; D J Kane; Shahrooz Rabizadeh; S B Schueller; J Yang; S Rabizadeh; Robert H Edwards
Neural-targeted gene therapy for rodent and primate hemiparkinsonism.
Experimental neurology 1994;127(2):207-18.
1994: Elliott J Mufson; J M Conner; S Varon; Jeffrey Kordower
Nerve growth factor-like immunoreactive profiles in the primate basal forebrain and hippocampal formation.
The Journal of comparative neurology 1994;341(4):507-19.
1993: Jeffrey Kordower; Elliott J Mufson; Ann-Charlotte E. Granholm-Bentley; Barry Hoffer; Phillip Friden
Delivery of trophic factors to the primate brain.
Experimental neurology 1993;124(1):21-30.
1993: S B Schueler; J D Ortega; Jacqueline Sagen; Jeffrey Kordower
Robust survival of isolated bovine adrenal chromaffin cells following intrastriatal transplantation: a novel hypothesis of adrenal graft viability.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(10):4496-510.
1993: W C Benzing; Jeffrey Kordower; Elliott J Mufson
Galanin immunoreactivity within the primate basal forebrain: evolutionary change between monkeys and apes.
The Journal of comparative neurology 1993;336(1):31-9.
1993: Elliott J Mufson; E Cochran; W Benzing; Jeffrey Kordower
Galaninergic innervation of the cholinergic vertical limb of the diagonal band (Ch2) and bed nucleus of the stria terminalis in aging, Alzheimer's disease and Down's syndrome.
Dementia (Basel, Switzerland) 1993;4(5):237-50.
1993: Jeffrey Kordower; Elliott J Mufson
NGF receptor (p75)-immunoreactivity in the developing primate basal ganglia.
The Journal of comparative neurology 1993;327(3):359-75.
1993: B H Wainer; Teresa Steininger; John D Roback; M A Burke-Watson; Elliott J Mufson; Jeffrey Kordower
Ascending cholinergic pathways: functional organization and implications for disease models.
Progress in brain research 1993;98():9-30.
1992: Jeffrey Kordower; Elliott J Mufson
Nerve growth factor receptor-immunoreactive neurons within the developing human cortex.
The Journal of comparative neurology 1992;323(1):25-41.
1992: Elliott J Mufson; T Brashers-Krug; Jeffrey Kordower
p75 nerve growth factor receptor immunoreactivity in the human brainstem and spinal cord.
Brain research 1992;589(1):115-23.
1992: Jeffrey Kordower; P Piecinski; P Rakic
Neurogenesis of the amygdaloid nuclear complex in the rhesus monkey.
Brain research. Developmental brain research 1992;68(1):9-15.
1992: Jeffrey Kordower; M Burke-Watson; John D Roback; B H Wainer
Stability of septohippocampal neurons following excitotoxic lesions of the rat hippocampus.
Experimental neurology 1992;117(1):1-16.
1992: Jeffrey Kordower; H K Le; Elliott J Mufson
Galanin immunoreactivity in the primate central nervous system.
The Journal of comparative neurology 1992;319(4):479-500.
1992: Manuel del Cerro; Jeffrey Kordower; E Lazar; D A Grover; C del Cerro
Photoreceptor differentiation in retinal xenografts of fetal monkey retina.
Brain research 1992;574(1-2):1-8.
1992: Elliott J Mufson; Jeffrey Kordower
Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):569-73.
1992: Jeffrey Kordower; K S Bankiewicz; Elliott J Mufson
NGF receptor (p75)-immunoreactivity within hypoglossal motor neurons following axotomy in monkeys.
Restorative neurology and neuroscience 1992;4(6):411-7.
1991: T B Freeman; M S Spence; B D Boss; D H Spector; R E Strecker; C Warren Olanow; Jeffrey Kordower
Development of dopaminergic neurons in the human substantia nigra.
Experimental neurology 1991;113(3):344-53.
1991: Elliott J Mufson; Gerry Higgins; Jeffrey Kordower
Nerve growth factor receptor immunoreactivity in the new world monkey (Cebus apella) and human cerebellum.
The Journal of comparative neurology 1991;308(4):555-75.
1991: Jeffrey Kordower; E Cochran; R D Penn; Christopher G Goetz
Putative chromaffin cell survival and enhanced host-derived TH-fiber innervation following a functional adrenal medulla autograft for Parkinson's disease.
Annals of neurology 1991;29(4):405-12.
1991: Elliott J Mufson; L N Presley; Jeffrey Kordower
Nerve growth factor receptor immunoreactivity within the nucleus basalis (Ch4) in Parkinson's disease: reduced cell numbers and co-localization with cholinergic neurons.
Brain research 1991;539(1):19-30.
1990: Elliott J Mufson; D R Brady; Jeffrey Kordower
Tracing neuronal connections in postmortem human hippocampal complex with the carbocyanine dye DiI.
Neurobiology of aging 1990;11(6):649-53.
1990: Jeffrey Kordower; Massimo Fiandaca; M F Notter; J T Hansen; D M Gash
NGF-like trophic support from peripheral nerve for grafted rhesus adrenal chromaffin cells.
Journal of neurosurgery 1990;73(3):418-28.
1990: Jeffrey Kordower; Massimo Fiandaca
Response of the monkey cholinergic septohippocampal system to fornix transection: a histochemical and cytochemical analysis.
The Journal of comparative neurology 1990;298(4):443-57.
1990: Jeffrey Kordower; Elliott J Mufson
Galanin-like immunoreactivity within the primate basal forebrain: differential staining patterns between humans and monkeys.
The Journal of comparative neurology 1990;294(2):281-92.
1990: Jeffrey Kordower; P Rakic
Neurogenesis of the magnocellular basal forebrain nuclei in the rhesus monkey.
The Journal of comparative neurology 1990;291(4):637-53.
1990: J T Hansen; Massimo Fiandaca; Jeffrey Kordower; M F Notter; D M Gash
Striatal adrenal medulla/sural nerve cografts in hemiparkinsonian monkeys.
Progress in brain research 1990;82():573-80.
1990: G Bing; M F Notter; J T Hansen; Carol K Kellogg; Jeffrey Kordower; D M Gash
Cografts of adrenal medulla with C6 glioma cells in rats with 6-hydroxydopamine-induced lesions.
Neuroscience 1990;34(3):687-97.
1989: M Christopher Newland; T L Ceckler; Jeffrey Kordower; B Weiss
Visualizing manganese in the primate basal ganglia with magnetic resonance imaging.
Experimental neurology 1989;106(3):251-8.
1989: Jeffrey Kordower; Elliott J Mufson
NGF and Alzheimer's disease: unfulfilled promise and untapped potential.
Neurobiology of aging 1989;10(5):543-4; discussion 552-3.
1989: Elliott J Mufson; Mark Bothwell; Jeffrey Kordower
Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain.
Experimental neurology 1989;105(3):221-32.
1989: J T Hansen; G Y Bing; M F Notter; Jeffrey Kordower; Massimo Fiandaca; D M Gash
Adrenal chromaffin cells as transplants in animal models of Parkinson's disease.
Journal of electron microscopy technique 1989;12(4):308-15.
1989: Elliott J Mufson; Mark Bothwell; Louis B Hersh; Jeffrey Kordower
Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons.
The Journal of comparative neurology 1989;285(2):196-217.
1989: Jeffrey Kordower; R T Bartus; F F Marciano; D M Gash
Telencephalic cholinergic system of the New World monkey (Cebus apella): morphological and cytoarchitectonic assessment and analysis of the projection to the amygdala.
The Journal of comparative neurology 1989;279(4):528-45.
1989: Elliott J Mufson; Jeffrey Kordower
Nerve growth factor receptor expressing human basal forebrain neurons: pathologic alterations in Alzheimer's and Parkinson's disease.
Progress in clinical and biological research 1989;317():401-14.
1989: Jeffrey Kordower; D M Gash; Mark Bothwell; Louis B Hersh; Elliott J Mufson
Nerve growth factor receptor and choline acetyltransferase remain colocalized in the nucleus basalis (Ch4) of Alzheimer's patients.
Neurobiology of aging 1989;10(1):67-74.
1988: Jeffrey Kordower; R T Bartus; Mark Bothwell; G Schatteman; D M Gash
Nerve growth factor receptor immunoreactivity in the nonhuman primate (Cebus apella): distribution, morphology, and colocalization with cholinergic enzymes.
The Journal of comparative neurology 1988;277(4):465-86.
1988: Jeffrey Kordower; J R Sladek; Massimo Fiandaca; G Y Bing; D M Gash
Tyrosine hydroxylase-immunoreactive somata within the primate subfornical organ: species specificity.
Brain research 1988;461(2):221-9.
1988: J T Hansen; Jeffrey Kordower; Massimo Fiandaca; S S Jiao; M F Notter; D M Gash
Adrenal medullary autografts into the basal ganglia of Cebus monkeys: graft viability and fine structure.
Experimental neurology 1988;102(1):65-75.
1988: Massimo Fiandaca; Jeffrey Kordower; J T Hansen; S S Jiao; D M Gash
Adrenal medullary autografts into the basal ganglia of Cebus monkeys: injury-induced regeneration.
Experimental neurology 1988;102(1):76-91.
1988: Jeffrey Kordower; D M Gash
Animal models of age- and disease-related cognitive decline: perspectives on the models and therapeutic strategies.
Neurobiology of aging 1988;9(5-6):685-9.
1988: Massimo Fiandaca; Jeffrey Kordower; J T Hansen; D M Gash
Adrenal medullary tissue grafting in Parkinson's disease.
Journal of neurosurgery 1988;69(1):150-2.
1988: Jeffrey Kordower; R L Dean; H C White; F F Marciano
Transplantation into the mammalian CNS: a meeting report on the sixth Schmitt neurological sciences symposium.
Neurobiology of aging 1988;9(1):127-37.
1987: Jeffrey Kordower; M F Notter; D M Gash
Neuroblastoma cells in neural transplants: a neuroanatomical and behavioral analysis.
Brain research 1987;417(1):85-98.
1987: Jeffrey Kordower; M F Notter; H H Yeh; D M Gash
An in vivo and in vitro assessment of differentiated neuroblastoma cells as a source of donor tissue for transplantation.
Annals of the New York Academy of Sciences 1987;495():606-22.
1986: R J Bodnar; L S Truesdell; J Haldar; I A Aral; Jeffrey Kordower; G Nilaver
Elimination of vasopressin analgesia following lesions placed in the rat hypothalamic paraventricular nucleus.
Peptides 1986;7(1):111-7.
1985: Jeffrey Kordower; R J Bodnar
Differential effects of dPTyr(Me)AVP, a vasopressin antagonist, upon foot shock analgesia.
The International journal of neuroscience 1985;28(3-4):269-78.
1984: Jeffrey Kordower; R J Bodnar
Vasopressin analgesia: specificity of action and non-opioid effects.
Peptides 1984;5(4):747-56.
1984: R J Bodnar; Jeffrey Kordower; A Reches; M M Wallace; Stanley Fahn
Reductions in pain thresholds and morphine analgesia following intracerebroventricular parachlorophenylalanine.
Pharmacology, biochemistry, and behavior 1984;21(1):79-84.
1983: R J Bodnar; D A Simone; Jeffrey Kordower; A L Kirchgessner; G Nilaver
Capsaicin treatment and stress-induced analgesia.
Pharmacology, biochemistry, and behavior 1983;18(1):65-71.
1982: R J Bodnar; N S Sharpless; Jeffrey Kordower; M Potegal; Gordon Barr
Analgesic responses following adrenal demedullation and peripheral catecholamine depletion.
Physiology & behavior 1982;29(6):1105-9.
1982: Jeffrey Kordower; V Sikorszky; R J Bodnar
Central antinociceptive effects of lysine-vasopressin and an analogue.
Peptides 1982;3(4):613-7.
1982: R J Bodnar; M M Wallace; Jeffrey Kordower; G Nilaver; J Cort; E A Zimmerman
Modulation of nociceptive thresholds by vasopressin in the Brattleboro and normal rat.
Annals of the New York Academy of Sciences 1982;394():735-9.
1981: S Fleischer; Jeffrey Kordower; B Kaplan; R Dicker; R Smerling; J Ilgner
Olfactory bulbectomy and gender differences in maternal behaviors of rats.
Physiology & behavior 1981;26(6):957-9.
1981: R J Bodnar; Jeffrey Kordower; M M Wallace; H Tamir
Stress and morphine analgesia: alterations following p-chlorophenylalanine.
Pharmacology, biochemistry, and behavior 1981;14(5):645-51.