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Oksana Lockridge

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TOP 3
Bin Li; Michael Eddleston; Peter Eyer; Wei Jiang; Lawrence M Schopfer; Oksana Lockridge
Protein tyrosine adduct in humans self-poisoned by chlorpyrifos.
Kevser Biberoglu; Ashima Saxena; Lawrence M Schopfer; Ozden Tacal; Oksana Lockridge
Polyproline tetramer organizing peptides in fetal bovine serum acetylcholinesterase.
Wei Jiang; Patrick Masson; Florian Nachon; Lawrence M Schopfer; John R Cashman; Oksana Lockridge
Mass spectrometry method to identify aging pathways of Sp- and Rp-tabun adducts on human butyrylcholinesterase based on the acid labile P-N bond.

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2013: Bin Li; Michael Eddleston; Peter Eyer; Wei Jiang; Lawrence M Schopfer; Oksana Lockridge
Protein tyrosine adduct in humans self-poisoned by chlorpyrifos.
Toxicology and applied pharmacology 2013;269(3):215-25.
2013: Kevser Biberoglu; Ashima Saxena; Lawrence M Schopfer; Ozden Tacal; Oksana Lockridge
Polyproline tetramer organizing peptides in fetal bovine serum acetylcholinesterase.
Biochimica et biophysica acta 2013;1834(4):745-53.
2013: Wei Jiang; Patrick Masson; Florian Nachon; Lawrence M Schopfer; John R Cashman; Oksana Lockridge
Mass spectrometry method to identify aging pathways of Sp- and Rp-tabun adducts on human butyrylcholinesterase based on the acid labile P-N bond.
Toxicological sciences : an official journal of the Society of Toxicology 2013;132(2):390-8.
2013: Wei Jiang; Oksana Lockridge
Detectable organophosphorus pesticide exposure in the blood of Nebraska and Iowa residents measured by mass spectrometry of butyrylcholinesterase adducts.
Chemico-biological interactions 2013;203(1):91-5.
2013: Mariya S Liyasova; Lawrence M Schopfer; Oksana Lockridge
Cresyl saligenin phosphate makes multiple adducts on free histidine, but does not form an adduct on histidine 438 of human butyrylcholinesterase.
Chemico-biological interactions 2013;203(1):103-7.
2013: Mariya S Liyasova; John E Casida; Sean Kodani; Stephen R Lantz; Lawrence M Schopfer; Oksana Lockridge
Newly observed spontaneous activation of ethephon as a butyrylcholinesterase inhibitor.
Chemical research in toxicology 2013;26(3):422-31.
2013: Ozden Tacal; Bin Li; Oksana Lockridge; Lawrence M Schopfer
Resistance of human butyrylcholinesterase to methylene blue-catalyzed photoinactivation; mass spectrometry analysis of oxidation products.
Photochemistry and photobiology 2013;89(2):336-48.
2013: Eugénie Carletti; Jacques-Philippe Colletier; Oksana Lockridge; Patrick Masson; Florian Nachon; Gianluca Santoni; Lawrence M Schopfer; Martin Weik
Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry.
Chemical research in toxicology 2013;26(2):280-9.
2012: Kevser Biberoglu; Lawrence M Schopfer; Ozden Tacal; Oksana Lockridge
The proline-rich tetramerization peptides in equine serum butyrylcholinesterase.
The FEBS journal 2012;279(20):3844-58.
2012: Mariya S Liyasova; Lawrence M Schopfer; Oksana Lockridge
Cresyl saligenin phosphate, an organophosphorus toxicant, makes covalent adducts with histidine, lysine, and tyrosine residues of human serum albumin.
Chemical research in toxicology 2012;25(8):1752-61.
2012: Xavier Brazzolotto; Ludovic Jean; Oksana Lockridge; Pierre-Yves Renard; Cyril Ronco; Marie Trovaslet; Marielle Wandhammer; Florian Nachon
Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure.
The FEBS journal 2012;279(16):2905-16.
2012: Wei Jiang; Ellen G Duysen; Oksana Lockridge
Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry.
Toxicology 2012;295(1-3):15-22.
2012: Lawrence M Schopfer; Oksana Lockridge
Analytical approaches for monitoring exposure to organophosphorus and carbamate agents through analysis of protein adducts.
Drug testing and analysis 2012;4(3-4):246-61.
2012: Ellen G Duysen; Patrick Masson; Florian Nachon; Lawrence M Schopfer; John R Cashman; Oksana Lockridge
Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran.
Chemico-biological interactions 2012;195(3):189-98.
2011: Ellen G Duysen; Frank Koentgen; Lawrence M Schopfer; Christopher M Timperley; Gareth R Williams; Douglas M Cerasoli; Oksana Lockridge
Production of ES1 plasma carboxylesterase knockout mice for toxicity studies.
Chemical research in toxicology 2011;24(11):1891-8.
2011: Mariya Liyasova; Clement E Furlong; Bin Li; Patrick Masson; Florian Nachon; Lawrence M Schopfer; Oksana Lockridge
Exposure to tri-o-cresyl phosphate detected in jet airplane passengers.
Toxicology and applied pharmacology 2011;256(3):337-47.
2011: Judit Marsillach; Rebecca J Richter; Lawrence M Schopfer; Richard C Stevens; Stephanie M Suzuki; Daniela M Tomazela; Jerry H Kim; Oksana Lockridge; Michael J MacCoss; Clement E Furlong
Biomarkers of organophosphorus (OP) exposures in humans.
Neurotoxicology 2011;32(5):656-60.
2011: Ellen G Duysen; Oksana Lockridge
Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons.
Toxicology and applied pharmacology 2011;255(2):214-20.
2011: Ellen G Duysen; Oksana Lockridge
Prolonged toxic effects after cocaine challenge in butyrylcholinesterase/plasma carboxylesterase double knockout mice: a model for butyrylcholinesterase-deficient humans.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(8):1321-3.
2011: Michael Adler; Ellen G Duysen; Tracey A Hamilton; Oksana Lockridge; Angela L Purcell; Richard E Sweeney; Sharad S Deshpande
Role of acetylcholinesterase on the structure and function of cholinergic synapses: insights gained from studies on knockout mice.
Cellular and molecular neurobiology 2011;31(6):909-20.
2011: Eugénie Carletti; Jacques-Philippe Colletier; Marie-Thérèse Froment; Oksana Lockridge; Florian Nachon; Lawrence M Schopfer; Martin Weik; Patrick Masson
Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis.
Chemical research in toxicology 2011;24(6):797-808.
2011: Oluwatoyin A Asojo; Oluyomi Adebola Asojo; Michelle N Ngamelue; Kohei Homma; Oksana Lockridge
Cocrystallization studies of full-length recombinant butyrylcholinesterase (BChE) with cocaine.
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 4):434-7.
2011: Alexandre Bazire; Emilie Gillon; Oksana Lockridge; Virginie Vallet; Florian Nachon
The kinetic study of the inhibition of human cholinesterases by demeton-S-methyl shows that cholinesterase-based titration methods are not suitable for this organophosphate.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(3):754-9.
2011: Kalpana Parikh; Ellen G Duysen; Benjamin Snow; Neil S Jensen; Veeraswamy Manne; Oksana Lockridge; Nageswararao Chilukuri
Gene-delivered butyrylcholinesterase is prophylactic against the toxicity of chemical warfare nerve agents and organophosphorus compounds.
The Journal of pharmacology and experimental therapeutics 2011;337(1):92-101.
2011: Ellen G Duysen; K Parikh; V Aleti; V Manne; Oksana Lockridge; N Chilukuri
Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon.
Gene therapy 2011;18(3):250-7.
2011: Florian Nachon; Eugenie Carletti; Marielle Wandhammer; Yvain Nicolet; Lawrence M Schopfer; Patrick Masson; Oksana Lockridge
X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger.
The Biochemical journal 2011;434(1):73-82.
2010: Patrick Masson; Florian Nachon; Oksana Lockridge
Structural approach to the aging of phosphylated cholinesterases.
Chemico-biological interactions 2010;187(1-3):157-62.
2010: Oksana Lockridge; Lawrence M Schopfer
Review of tyrosine and lysine as new motifs for organophosphate binding to proteins that have no active site serine.
Chemico-biological interactions 2010;187(1-3):344-8.
2010: Shelley Camp; Limin Zhang; Eric Krejci; Alexandre Dobbertin; Véronique Bernard; Emmanuelle Girard; Ellen G Duysen; Oksana Lockridge; Antonella De Jaco; Palmer Taylor
Contributions of selective knockout studies to understanding cholinesterase disposition and function.
Chemico-biological interactions 2010;187(1-3):72-7.
2010: Andrea Gaydess; Ellen G Duysen; Yuan Li; Vladimir Gilman; Alexander Kabanov; Oksana Lockridge; Tatiana Bronich
Visualization of exogenous delivery of nanoformulated butyrylcholinesterase to the central nervous system.
Chemico-biological interactions 2010;187(1-3):295-8.
2010: Lawrence M Schopfer; Clement E Furlong; Oksana Lockridge
Development of diagnostics in the search for an explanation of aerotoxic syndrome.
Analytical biochemistry 2010;404(1):64-74.
2010: Bin Li; Ivan Ricordel; Lawrence M Schopfer; Frédéric Baud; Bruno Mégarbane; Patrick Masson; Oksana Lockridge
Dichlorvos, chlorpyrifos oxon and Aldicarb adducts of butyrylcholinesterase, detected by mass spectrometry in human plasma following deliberate overdose.
Journal of applied toxicology : JAT 2010;30(6):559-65.
2010: Bin Li; Ivan Ricordel; Lawrence M Schopfer; Frédéric Baud; Bruno Mégarbane; Florian Nachon; Patrick Masson; Oksana Lockridge
Detection of adduct on tyrosine 411 of albumin in humans poisoned by dichlorvos.
Toxicological sciences : an official journal of the Society of Toxicology 2010;116(1):23-31.
2010: Ozden Tacal; Oksana Lockridge
Methamidophos, dichlorvos, O-methoate and diazinon pesticides used in Turkey make a covalent bond with butyrylcholinesterase detected by mass spectrometry.
Journal of applied toxicology : JAT 2010;30(5):469-75.
2010: Lawrence M Schopfer; Hasmik Grigoryan; Bin Li; Florian Nachon; Patrick Masson; Oksana Lockridge
Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(17-18):1297-311.
2010: Wei Jiang; Ellen G Duysen; Heidi Hansen; Luda Shlyakhtenko; Lawrence M Schopfer; Oksana Lockridge
Mice treated with chlorpyrifos or chlorpyrifos oxon have organophosphorylated tubulin in the brain and disrupted microtubule structures, suggesting a role for tubulin in neurotoxicity associated with exposure to organophosphorus agents.
Toxicological sciences : an official journal of the Society of Toxicology 2010;115(1):183-93.
2010: Mariya S Liyasova; Lawrence M Schopfer; Oksana Lockridge
Reaction of human albumin with aspirin in vitro: mass spectrometric identification of acetylated lysines 199, 402, 519, and 545.
Biochemical pharmacology 2010;79(5):784-91.
2010: Patrick Masson; Oksana Lockridge
Butyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behavior.
Archives of biochemistry and biophysics 2010;494(2):107-20.
2010: Anna Hrabovska; Vladimir Farar; Veronique Bernard; Ellen G Duysen; Jiri Brabec; Oksana Lockridge; Jaromir Myslivecek
Drastic decrease in dopamine receptor levels in the striatum of acetylcholinesterase knock-out mouse.
Chemico-biological interactions 2010;183(1):194-201.
2009: Hasmik Grigoryan; Bin Li; Weihua Xue; Marine Grigoryan; Lawrence M Schopfer; Oksana Lockridge
Mass spectral characterization of organophosphate-labeled lysine in peptides.
Analytical biochemistry 2009;394(1):92-100.
2009: Hasmik Grigoryan; Lawrence M Schopfer; Eric S Peeples; Ellen G Duysen; Marine Grigoryan; Charles M Thompson; Oksana Lockridge
Mass spectrometry identifies multiple organophosphorylated sites on tubulin.
Toxicology and applied pharmacology 2009;240(2):149-58.
2009: Hasmik Grigoryan; Oksana Lockridge
Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon: implications for neurotoxicity.
Toxicology and applied pharmacology 2009;240(2):143-8.
2009: Cynthia Gilley; Mary MacDonald; Florian Nachon; Lawrence M Schopfer; Jun Zhang; John R Cashman; Oksana Lockridge
Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase.
Chemical research in toxicology 2009;22(10):1680-8.
2009: Nageswararao Chilukuri; Ellen G Duysen; Kalpana Parikh; Robert diTargiani; Bhupendra P Doctor; Oksana Lockridge; Ashima Saxena
Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents.
Molecular pharmacology 2009;76(3):612-7.
2009: Hasmik Grigoryan; Bin Li; Erica K Anderson; Weihua Xue; Florian Nachon; Oksana Lockridge; Lawrence M Schopfer
Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine.
Chemico-biological interactions 2009;180(3):492-8.
2009: Noel D Johnson; Ellen G Duysen; Oksana Lockridge
Intrathecal delivery of fluorescent labeled butyrylcholinesterase to the brains of butyrylcholinesterase knock-out mice: visualization and quantification of enzyme distribution in the brain.
Neurotoxicology 2009;30(3):386-92.
2009: Ellen G Duysen; Bin Li; Oksana Lockridge
The butyrylcholinesterase knockout mouse a research tool in the study of drug sensitivity, bio-distribution, obesity and Alzheimer's disease.
Expert opinion on drug metabolism & toxicology 2009;5(5):523-8.
2009: He Li; Ivan Ricordel; Larry Tong; Lawrence M Schopfer; Frédéric Baud; Bruno Mégarbane; Eric Maury; Patrick Masson; Oksana Lockridge
Carbofuran poisoning detected by mass spectrometry of butyrylcholinesterase adduct in human serum.
Journal of applied toxicology : JAT 2009;29(2):149-55.
2009: Runa S Naik; Joachim Hartmann; Cornelia Kiewert; Ellen G Duysen; Oksana Lockridge; Jochen Klein
Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2009;12(1):79-85.
2009: Bin Li; Lawrence M Schopfer; Hasmik Grigoryan; Charles M Thompson; Steven H Hinrichs; Patrick Masson; Oksana Lockridge
Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine.
Toxicological sciences : an official journal of the Society of Toxicology 2009;107(1):144-55.
2008: Ellen G Duysen; Bin Li; Michaela Carlson; Yi-Fan Li; Stacy Wieseler; Steven H Hinrichs; Oksana Lockridge
Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice.
Basic & clinical pharmacology & toxicology 2008;103(6):514-21.
2008: Eugénie Carletti; He Li; Bin Li; Fredrik Ekström; Yvain Nicolet; Mélanie Loiodice; Emilie Gillon; Marie-Thérèse Froment; Oksana Lockridge; Lawrence M Schopfer; Patrick Masson; Florian Nachon
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation.
Journal of the American Chemical Society 2008;130(47):16011-20.
2008: He Li; Larry Tong; Lawrence M Schopfer; Patrick Masson; Oksana Lockridge
Fast affinity purification coupled with mass spectrometry for identifying organophosphate labeled plasma butyrylcholinesterase.
Chemico-biological interactions 2008;175(1-3):68-72.
2008: Patrick Masson; Florian Nachon; Clarence A Broomfield; David Lenz; Laurent Verdier; Lawrence M Schopfer; Oksana Lockridge
A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters.
Chemico-biological interactions 2008;175(1-3):273-80.
2008: Hasmik Grigoryan; Lawrence M Schopfer; Charles M Thompson; Alvin V Terry; Patrick Masson; Oksana Lockridge
Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents.
Chemico-biological interactions 2008;175(1-3):180-6.
2008: Nageswararao Chilukuri; Ellen G Duysen; Kalpana Parikh; Wei Sun; Bhupendra P Doctor; Oksana Lockridge; Ashima Saxena
Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo.
Chemico-biological interactions 2008;175(1-3):327-31.
2008: Ellen G Duysen; Oksana Lockridge
Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase.
Chemico-biological interactions 2008;175(1-3):119-24.
2008: Bin Li; Ellen G Duysen; Oksana Lockridge
The butyrylcholinesterase knockout mouse is obese on a high-fat diet.
Chemico-biological interactions 2008;175(1-3):88-91.
2008: Shi-Jian Ding; John Carr; James E Carlson; Larry Tong; Weihua Xue; Yifeng Li; Lawrence M Schopfer; Bin Li; Florian Nachon; Oluwatoyin Asojo; Charles M Thompson; Steven H Hinrichs; Patrick Masson; Oksana Lockridge
Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin.
Chemical research in toxicology 2008;21(9):1787-94.
2008: Oksana Lockridge; Weihua Xue; Andrea Gaydess; Hasmik Grigoryan; Shi-Jian Ding; Lawrence M Schopfer; Steven H Hinrichs; Patrick Masson
Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines.
The Journal of biological chemistry 2008;283(33):22582-90.
2008: Sultan Darvesh; Katherine V Darvesh; Robert S McDonald; Diane Mataija; Ryan Walsh; Sam Mothana; Oksana Lockridge; Earl Martin
Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase.
Journal of medicinal chemistry 2008;51(14):4200-12.
2008: Patrick Masson; Marie-Thérèse Froment; Emilie Gillon; Florian Nachon; Oksana Lockridge; Lawrence M Schopfer
Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters.
The FEBS journal 2008;275(10):2617-31.
2008: Joachim Hartmann; Cornelia Kiewert; Ellen G Duysen; Oksana Lockridge; Jochen Klein
Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice.
Neurochemistry international 2008;52(6):972-8.
2008: He Li; Lawrence M Schopfer; Patrick Masson; Oksana Lockridge
Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers.
The Biochemical journal 2008;411(2):425-32.
2008: Liya R Mikami; Stacy Wieseler; Ricardo L R Souza; Lawrence M Schopfer; Florian Nachon; Oksana Lockridge; Eleidi A Chautard-Freire-Maia
Five new naturally occurring mutations of the BCHE gene and frequencies of 12 butyrylcholinesterase alleles in a Brazilian population.
Pharmacogenetics and genomics 2008;18(3):213-8.
2008: Bin Li; Ellen G Duysen; Michaela Carlson; Oksana Lockridge
The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency.
The Journal of pharmacology and experimental therapeutics 2008;324(3):1146-54.
2008: Bin Li; Florian Nachon; Marie-Thérèse Froment; Laurent Verdier; Jean-Claude Debouzy; Bernardo Brasme; Emilie Gillon; Lawrence M Schopfer; Oksana Lockridge; Patrick Masson
Binding and hydrolysis of soman by human serum albumin.
Chemical research in toxicology 2008;21(2):421-31.
2007: He Li; Lawrence M Schopfer; Florian Nachon; Marie-Thérèse Froment; Patrick Masson; Oksana Lockridge
Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry.
Toxicological sciences : an official journal of the Society of Toxicology 2007;100(1):136-45.
2007: Jaromír Myslivecek; Ellen G Duysen; Oksana Lockridge
Adaptation to excess acetylcholine by downregulation of adrenoceptors and muscarinic receptors in lungs of acetylcholinesterase knockout mice.
Naunyn-Schmiedeberg's archives of pharmacology 2007;376(1-2):83-92.
2007: Michelle N Ngamelue; Kohei Homma; Oksana Lockridge; Oluwatoyin A Asojo
Crystallization and X-ray structure of full-length recombinant human butyrylcholinesterase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 9):723-7.
2007: Liya R Mikami; Stacy Wieseler; Ricardo L R Souza; Lawrence M Schopfer; Oksana Lockridge; Eleidi A Chautard-Freire-Maia
Expression of three naturally occurring genetic variants (G75R, E90D, I99M) of the BCHE gene of human butyrylcholinesterase.
Pharmacogenetics and genomics 2007;17(9):681-5.
2007: Patrick Masson; Marie-Thérèse Froment; Sultan Darvesh; Lawrence M Schopfer; Oksana Lockridge
Aryl acylamidase activity of human serum albumin with o-nitrotrifluoroacetanilide as the substrate.
Journal of enzyme inhibition and medicinal chemistry 2007;22(4):463-9.
2007: Stephen G Rice; Lee Nowak; Ellen G Duysen; Oksana Lockridge; Debomoy K Lahiri; Patricio Reyes
Neuropathological and immunochemical studies of brain parenchyma in acetylcholinesterase knockout mice: implications in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2007;11(4):481-9.
2007: Yifeng Li; Xia Li; He Li; Oksana Lockridge; Guangshun Wang
A novel method for purifying recombinant human host defense cathelicidin LL-37 by utilizing its inherent property of aggregation.
Protein expression and purification 2007;54(1):157-65.
2007: Indumathi Manoharan; A Kuznetsova; J D Fisk; Rathnam Boopathy; Oksana Lockridge; Sultan Darvesh
Comparison of cognitive functions between people with silent and wild-type butyrylcholinesterase.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(7):939-45.
2007: Ellen G Duysen; Bin Li; Sultan Darvesh; Oksana Lockridge
Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission.
Toxicology 2007;233(1-3):60-9.
2007: Joachim Hartmann; Cornelia Kiewert; Ellen G Duysen; Oksana Lockridge; Nigel H Greig; Jochen Klein
Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity.
Journal of neurochemistry 2007;100(5):1421-9.
2007: Indumathi Manoharan; Rathnam Boopathy; Sultan Darvesh; Oksana Lockridge
A medical health report on individuals with silent butyrylcholinesterase in the Vysya community of India.
Clinica chimica acta; international journal of clinical chemistry 2007;378(1-2):128-35.
2007: Bin Li; Lawrence M Schopfer; Steven H Hinrichs; Patrick Masson; Oksana Lockridge
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry assay for organophosphorus toxicants bound to human albumin at Tyr411.
Analytical biochemistry 2007;361(2):263-72.
2007: Patrick Masson; Marie-Thérèse Froment; Emilie Gillon; Florian Nachon; Oksana Lockridge; Lawrence M Schopfer
Hydrolysis of oxo- and thio-esters by human butyrylcholinesterase.
Biochimica et biophysica acta 2007;1774(1):16-34.
2006: Thomas Poyot; Florian Nachon; Marie-Thérèse Froment; Mélanie Loiodice; Stacy Wieseler; Lawrence M Schopfer; Oksana Lockridge; Patrick Masson
Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters.
Biochimica et biophysica acta 2006;1764(9):1470-8.
2006: Bin Li; Ellen G Duysen; Larisa Poluektova; Leonard Murrin; Oksana Lockridge
Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase.
Toxicology and applied pharmacology 2006;214(2):152-65.
2006: Indumathi Manoharan; Stacy Wieseler; Paul G Layer; Oksana Lockridge; Rathnam Boopathy
Naturally occurring mutation Leu307Pro of human butyrylcholinesterase in the Vysya community of India.
Pharmacogenetics and genomics 2006;16(7):461-8.
2006: Antonella De Jaco; Davide Comoletti; Zrinka Kovarik; Guido Gaietta; Zoran Radic; Oksana Lockridge; Mark H Ellisman; Palmer Taylor
A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family.
The Journal of biological chemistry 2006;281(14):9667-76.
2006: Bin Li; Ellen G Duysen; Thomas L Saunders; Oksana Lockridge
Production of the butyrylcholinesterase knockout mouse.
Journal of molecular neuroscience : MN 2006;30(1-2):193-5.
2006: Stacy Wieseler; Lawrence M Schopfer; Oksana Lockridge
Markers of organophosphate exposure in human serum.
Journal of molecular neuroscience : MN 2006;30(1-2):93-4.
2006: Ellen G Duysen; Oksana Lockridge
Phenotype comparison of three acetylcholinesterase knockout strains.
Journal of molecular neuroscience : MN 2006;30(1-2):91-2.
2006: Bin Li; Ellen G Duysen; Oksana Lockridge
Gene transfer of acetylcholinesterase protects the knockout mouse from the toxicity of DFP.
Journal of molecular neuroscience : MN 2006;30(1-2):79-80.
2005: Florian Nachon; Oluwatoyin A Asojo; Gloria E. Borgstahl; Patrick Masson; Oksana Lockridge
Structural data on the aging of diethylphosphoryl-butyrylcholinesterase.
Chemico-biological interactions 2005;157-158():408-9.
2005: He Li; Lawrence M Schopfer; Reggie S Spaulding; Charles M Thompson; Oksana Lockridge
Identification of organophosphate-reactive proteins by tandem mass spectrometry.
Chemico-biological interactions 2005;157-158():383-4.
2005: Patrick Masson; Lawrence M Schopfer; Marie-Thérèse Froment; Jean-Claude Debouzy; Florian Nachon; Emilie Gillon; Oksana Lockridge; Anna Hrabovska; Boris N Goldstein
Hysteresis of butyrylcholinesterase in the approach to steady-state kinetics.
Chemico-biological interactions 2005;157-158():143-52.
2005: Anna Hrabovska; Ellen G Duysen; Jeff D Sanders; Leonard Murrin; Oksana Lockridge
Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse.
Chemico-biological interactions 2005;157-158():71-8.
2005: Bin Li; Meghan Sedlacek; Indumathi Manoharan; Rathnam Boopathy; Ellen G Duysen; Patrick Masson; Oksana Lockridge
Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma.
Biochemical pharmacology 2005;70(11):1673-84.
2005: Lawrence M Schopfer; Matthew M Champion; Nate Tamblyn; Charles M Thompson; Oksana Lockridge
Characteristic mass spectral fragments of the organophosphorus agent FP-biotin and FP-biotinylated peptides from trypsin and bovine albumin (Tyr410).
Analytical biochemistry 2005;345(1):122-32.
2005: Javier Sáez-Valero; José A Pérez de Gracia; Oksana Lockridge
Intraperitoneal administration of 340 kDa human plasma butyrylcholinesterase increases the level of the enzyme in the cerebrospinal fluid of rats.
Neuroscience letters 2005;383(1-2):93-8.
2005: Oksana Lockridge; Charles M Thompson; Troy Voelker; Ellen G Duysen; Lawrence M Schopfer
Life without acetylcholinesterase: the implications of cholinesterase inhibitor toxicity in AChE-knockout mice.
Environmental toxicology and pharmacology 2005;19(3):463-9.
2005: Lawrence M Schopfer; Troy Voelker; Cynthia F Bartels; Charles M Thompson; Oksana Lockridge
Reaction kinetics of biotinylated organophosphorus toxicant, FP-biotin, with human acetylcholinesterase and human butyrylcholinesterase.
Chemical research in toxicology 2005;18(4):747-54.
2005: Florian Nachon; Oluwatoyin A Asojo; Gloria E. Borgstahl; Patrick Masson; Oksana Lockridge
Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging.
Biochemistry 2005;44(4):1154-62.
2005: Eric S Peeples; Lawrence M Schopfer; Ellen G Duysen; Reggie S Spaulding; Troy Voelker; Charles M Thompson; Oksana Lockridge
Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry.
Toxicological sciences : an official journal of the Society of Toxicology 2005;83(2):303-12.
2004: Afrim H Bytyqi; Oksana Lockridge; Ellen Duysen; Yuxia Wang; Uwe Wolfrum; Paul G Layer
Impaired formation of the inner retina in an AChE knockout mouse results in degeneration of all photoreceptors.
The European journal of neuroscience 2004;20(11):2953-62.
2004: Michael Adler; Heather A Manley; Angela L Purcell; Sharad S Deshpande; Tracey A Hamilton; Robert K Kan; George A Oyler; Oksana Lockridge; Ellen G Duysen; Robert E Sheridan
Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice.
Muscle & nerve 2004;30(3):317-27.
2004: Yuxia Wang; Lawrence M Schopfer; Ellen G Duysen; Florian Nachon; Patrick Masson; Oksana Lockridge
Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants.
Analytical biochemistry 2004;329(1):131-8.
2004: Patrick Masson; Nicole Bec; Marie-Thérèse Froment; Florian Nachon; Claude Balny; Oksana Lockridge; Lawrence M Schopfer
Rate-determining step of butyrylcholinesterase-catalyzed hydrolysis of benzoylcholine and benzoylthiocholine. Volumetric study of wild-type and D70G mutant behavior.
European journal of biochemistry / FEBS 2004;271(10):1980-90.
2004: Yuxia Wang; Andreea Ticu Boeck; Ellen G Duysen; Margaret Van Keuren; Thomas L Saunders; Oksana Lockridge
Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase.
Toxicology and applied pharmacology 2004;196(3):356-66.
2004: Patrick Masson; Boris N Goldstein; Jean-Claude Debouzy; Marie-Thérèse Froment; Oksana Lockridge; Lawrence M Schopfer
Damped oscillatory hysteretic behaviour of butyrylcholinesterase with benzoylcholine as substrate.
European journal of biochemistry / FEBS 2004;271(1):220-34.
2003: Laura A Volpicelli-Daley; Anna Hrabovska; Ellen G Duysen; Shawn M Ferguson; Randy D Blakely; Oksana Lockridge; Allan Levey
Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice.
Molecular pharmacology 2003;64(6):1309-16.
2003: Ashima Saxena; James M Fedorko; C R Vinayaka; Rohit Medhekar; Zoran Radić; Palmer Taylor; Oksana Lockridge; Bhupendra P Doctor
Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases.
European journal of biochemistry / FEBS 2003;270(22):4447-58.
2003: Yvain Nicolet; Oksana Lockridge; Patrick Masson; Juan C Fontecilla-Camps; Florian Nachon
Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
The Journal of biological chemistry 2003;278(42):41141-7.
2003: Laura A Volpicelli-Daley; Ellen G Duysen; Oksana Lockridge; Allan Levey
Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice.
Annals of neurology 2003;53(6):788-96.
2003: Véronique Bernard; Corinne Brana; Isabel Liste; Oksana Lockridge; Bertrand Bloch
Dramatic depletion of cell surface m2 muscarinic receptor due to limited delivery from intracytoplasmic stores in neurons of acetylcholinesterase-deficient mice.
Molecular and cellular neurosciences 2003;23(1):121-33.
2003: Bin Li; Ellen G Duysen; Laura A Volpicelli-Daley; Allan Levey; Oksana Lockridge
Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice.
Pharmacology, biochemistry, and behavior 2003;74(4):977-86.
2003: Patrick Masson; Florian Nachon; Cynthia F Bartels; Marie-Thérèse Froment; Fabien Ribes; Cedric Matthews; Oksana Lockridge
High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine.
European journal of biochemistry / FEBS 2003;270(2):315-24.
2002: J Eric Haux; Oksana Lockridge; John E Casida
Specificity of ethephon as a butyrylcholinesterase inhibitor and phosphorylating agent.
Chemical research in toxicology 2002;15(12):1527-33.
2002: Ellen G Duysen; Debra L Fry; Oksana Lockridge
Early weaning and culling eradicated Helicobacter hepaticus from an acetylcholinesterase knockout 129S6/SvEvTac mouse colony.
Comparative medicine 2002;52(5):461-6.
2002: Ellen G Duysen; Cynthia F Bartels; Oksana Lockridge
Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity.
The Journal of pharmacology and experimental therapeutics 2002;302(2):751-8.
2002: Hong Sun; Maryann L Shen; Yuan-Ping Pang; Oksana Lockridge; Stephen Brimijoin
Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase.
The Journal of pharmacology and experimental therapeutics 2002;302(2):710-6.
2002: Hong Sun; Yuan-Ping Pang; Oksana Lockridge; Stephen Brimijoin
Re-engineering butyrylcholinesterase as a cocaine hydrolase.
Molecular pharmacology 2002;62(2):220-4.
2002: Ellen G Duysen; Judith A Stribley; Debra L Fry; Steven H Hinrichs; Oksana Lockridge
Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet; phenotype of the adult acetylcholinesterase deficient mouse.
Brain research. Developmental brain research 2002;137(1):43-54.
2002: Andreea Ticu Boeck; Lawrence M Schopfer; Oksana Lockridge
DNA sequence of butyrylcholinesterase from the rat: expression of the protein and characterization of the properties of rat butyrylcholinesterase.
Biochemical pharmacology 2002;63(12):2101-10.
2002: Andreea Ticu Boeck; Debra L Fry; Antonio Sastre; Oksana Lockridge
Naturally occurring mutation, Asp70his, in human butyrylcholinesterase.
Annals of clinical biochemistry 2002;39(Pt 2):154-6.
2002: Patrick Masson; Lawrence M Schopfer; Cynthia F Bartels; Marie-Thérèse Froment; Fabien Ribes; Florian Nachon; Oksana Lockridge
Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite.
Biochimica et biophysica acta 2002;1594(2):313-24.
2002: Marek-Marsel Mesulam; Angela L Guillozet; Pamela Shaw; Allan Levey; Ellen G Duysen; Oksana Lockridge
Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine.
Neuroscience 2002;110(4):627-39.
2002: Florian Nachon; Yvain Nicolet; Nathalie Viguié; Patrick Masson; Juan C Fontecilla-Camps; Oksana Lockridge
Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization.
European journal of biochemistry / FEBS 2002;269(2):630-7.
2001: Denis Josse; Oksana Lockridge; W Xie; Cynthia F Bartels; Lawrence M Schopfer; Patrick Masson
The active site of human paraoxonase (PON1).
Journal of applied toxicology : JAT 2001;21 Suppl 1():S7-11.
2001: Ellen G Duysen; B Li; W Xie; Lawrence M Schopfer; R S Anderson; Clarence A Broomfield; Oksana Lockridge
Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality.
The Journal of pharmacology and experimental therapeutics 2001;299(2):528-35.
2001: H Sun; J El Yazal; Oksana Lockridge; Lawrence M Schopfer; Stephen Brimijoin; Yuan-Ping Pang
Predicted Michaelis-Menten complexes of cocaine-butyrylcholinesterase. Engineering effective butyrylcholinesterase mutants for cocaine detoxication.
The Journal of biological chemistry 2001;276(12):9330-6.
2001: Patrick Masson; W Xie; Marie-Thérèse Froment; Oksana Lockridge
Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase.
Biochimica et biophysica acta 2001;1544(1-2):166-76.
2000: Bin Li; Judith A Stribley; A Ticu; W Xie; Lawrence M Schopfer; P Hammond; Stephen Brimijoin; Steven H Hinrichs; Oksana Lockridge
Abundant tissue butyrylcholinesterase and its possible function in the acetylcholinesterase knockout mouse.
Journal of neurochemistry 2000;75(3):1320-31.
2000: Cynthia F Bartels; W Xie; Amanda K Miller-Lindholm; Lawrence M Schopfer; Oksana Lockridge
Determination of the DNA sequences of acetylcholinesterase and butyrylcholinesterase from cat and demonstration of the existence of both in cat plasma.
Biochemical pharmacology 2000;60(4):479-87.
2000: W Xie; Judith A Stribley; A Chatonnet; Phillip J Wilder; Angie Rizzino; Rodney D McComb; P Taylor; Steven H Hinrichs; Oksana Lockridge
Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase.
The Journal of pharmacology and experimental therapeutics 2000;293(3):896-902.
2000: Oksana Lockridge; Patrick Masson
Pesticides and susceptible populations: people with butyrylcholinesterase genetic variants may be at risk.
Neurotoxicology 2000;21(1-2):113-26.
2000: CV Altamirano; Cynthia F Bartels; Oksana Lockridge
The butyrylcholinesterase K-variant shows similar cellular protein turnover and quaternary interaction to the wild-type enzyme.
Journal of neurochemistry 2000;74(2):869-77.
1999: CV Altamirano; Oksana Lockridge
Conserved aromatic residues of the C-terminus of human butyrylcholinesterase mediate the association of tetramers.
Biochemistry 1999;38(40):13414-22.
1999: Patrick Masson; W Xie; Marie-Thérèse Froment; V Levitsky; PL Fortier; C Albaret; Oksana Lockridge
Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates.
Biochimica et biophysica acta 1999;1433(1-2):281-93.
1999: Clarence A Broomfield; Oksana Lockridge; Charles B Millard
Protein engineering of a human enzyme that hydrolyzes V and G nerve agents: design, construction and characterization.
Chemico-biological interactions 1999;119-120():413-8.
1999: W Xie; Phillip J Wilder; Judith A Stribley; A Chatonnet; Angie Rizzino; P Taylor; Steven H Hinrichs; Oksana Lockridge
Knockout of one acetylcholinesterase allele in the mouse.
Chemico-biological interactions 1999;119-120():289-99.
1999: Denis Josse; W Xie; Patrick Masson; Lawrence M Schopfer; Oksana Lockridge
Tryptophan residue(s) as major components of the human serum paraoxonase active site.
Chemico-biological interactions 1999;119-120():79-84.
1999: Denis Josse; W Xie; Patrick Masson; Oksana Lockridge
Human serum paraoxonase (PON1): identification of essential amino acid residues by group-selective labelling and site-directed mutagenesis.
Chemico-biological interactions 1999;119-120():71-8.
1999: Ashima Saxena; A M Redman; X Jiang; Oksana Lockridge; Bhupendra P Doctor
Differences in active-site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase.
Chemico-biological interactions 1999;119-120():61-9.
1999: CV Altamirano; Oksana Lockridge
Association of tetramers of human butyrylcholinesterase is mediated by conserved aromatic residues of the carboxy terminus.
Chemico-biological interactions 1999;119-120():53-60.
1999: Patrick Masson; PL Fortier; C Albaret; C Cléry; P Guerra; Oksana Lockridge
Structural and hydration changes in the active site gorge of phosporhylated butyrylcholinesterase accompanying the aging process.
Chemico-biological interactions 1999;119-120():17-27.
1999: Denis Josse; W Xie; Frédérique Renault; Daniel Rochu; Lawrence M Schopfer; Patrick Masson; Oksana Lockridge
Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities.
Biochemistry 1999;38(9):2816-25.
1999: V Levitsky; W Xie; Marie-Thérèse Froment; Oksana Lockridge; Patrick Masson
Polyol-induced activation by excess substrate of the D70G butyrylcholinesterase mutant.
Biochimica et biophysica acta 1999;1429(2):422-30.
1999: W Xie; CV Altamirano; Cynthia F Bartels; R J Speirs; J R Cashman; Oksana Lockridge
An improved cocaine hydrolase: the A328Y mutant of human butyrylcholinesterase is 4-fold more efficient.
Molecular pharmacology 1999;55(1):83-91.
1998: L E Vanlinthout; Cynthia F Bartels; Oksana Lockridge; K Callens; L H Booij
Prolonged paralysis after a test dose of mivacurium in a patient with atypical serum cholinesterase.
Anesthesia and analgesia 1998;87(5):1199-202.
1998: Ashima Saxena; Carol Viragh; D S Frazier; Ildiko M Kovach; Donald M Maxwell; Oksana Lockridge; Bhupendra P Doctor
The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism.
Biochemistry 1998;37(43):15086-96.
1998: Patrick Masson; Denis Josse; Oksana Lockridge; N Viguié; C Taupin; Cyril Buhler
Enzymes hydrolyzing organophosphates as potential catalytic scavengers against organophosphate poisoning.
Journal of physiology, Paris 1998;92(5-6):357-62.
1998: Marie-Thérèse Froment; Oksana Lockridge; Patrick Masson
Resistance of butyrylcholinesterase to inactivation by ultrasound: effects of ultrasound on catalytic activity and subunit association.
Biochimica et biophysica acta 1998;1387(1-2):53-64.
1998: Patrick Masson; Marie-Thérèse Froment; PL Fortier; J E Visicchio; Cynthia F Bartels; Oksana Lockridge
Butyrylcholinesterase-catalysed hydrolysis of aspirin, a negatively charged ester, and aspirin-related neutral esters.
Biochimica et biophysica acta 1998;1387(1-2):41-52.
1998: Charles B Millard; Oksana Lockridge; Clarence A Broomfield
Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase.
Biochemistry 1998;37(1):237-47.
1997: Ashima Saxena; A M Redman; X Jiang; Oksana Lockridge; Bhupendra P Doctor
Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase.
Biochemistry 1997;36(48):14642-51.
1997: R M Blong; Elliott Bedows; Oksana Lockridge
Tetramerization domain of human butyrylcholinesterase is at the C-terminus.
The Biochemical journal 1997;327 ( Pt 3)():747-57.
1997: Patrick Masson; PL Fortier; C Albaret; Marie-Thérèse Froment; Cynthia F Bartels; Oksana Lockridge
Aging of di-isopropyl-phosphorylated human butyrylcholinesterase.
The Biochemical journal 1997;327 ( Pt 2)():601-7.
1997: Patrick Masson; Marie-Thérèse Froment; Cynthia F Bartels; Oksana Lockridge
Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase.
The Biochemical journal 1997;325 ( Pt 1)():53-61.
1997: Patrick Masson; P Legrand; Cynthia F Bartels; Marie-Thérèse Froment; Lawrence M Schopfer; Oksana Lockridge
Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase.
Biochemistry 1997;36(8):2266-77.
1997: Oksana Lockridge; R M Blong; Patrick Masson; Marie-Thérèse Froment; Charles B Millard; Clarence A Broomfield
A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase.
Biochemistry 1997;36(4):786-95.
1996: Patrick Masson; Marie-Thérèse Froment; Cynthia F Bartels; Oksana Lockridge
Asp7O in the peripheral anionic site of human butyrylcholinesterase.
European journal of biochemistry / FEBS 1996;235(1-2):36-48.
1995: Charles B Millard; Oksana Lockridge; Clarence A Broomfield
Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase.
Biochemistry 1995;34(49):15925-33.
1995: RC Sorenson; SL Primo-Parmo; CL Kuo; S Adkins; Oksana Lockridge; Bert N La Du
Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7187-91.
1994: O Jbilo; Cynthia F Bartels; Arnaud Chatonnet; Jean-Pierre Toutant; Oksana Lockridge
Tissue distribution of human acetylcholinesterase and butyrylcholinesterase messenger RNA.
Toxicon : official journal of the International Society on Toxinology 1994;32(11):1445-57.
1994: M Kris; O Jbilo; Cynthia F Bartels; Patrick Masson; S Rhode; Oksana Lockridge
Endogenous butyrylcholinesterase in SV40 transformed cell lines: COS-1, COS-7, MRC-5 SV40, and WI-38 VA13.
In vitro cellular & developmental biology. Animal 1994;30A(10):680-9.
1994: J R Huth; S E Norton; Oksana Lockridge; T Shikone; A J Hsueh; RW Ruddon
Bacterial expression and in vitro folding of the beta-subunit of human chorionic gonadotropin (hCG beta) and functional assembly of recombinant hCG beta with hCG alpha.
Endocrinology 1994;135(3):911-8.
1994: O Jbilo; Jean-Pierre Toutant; K P Vatsis; Arnaud Chatonnet; Oksana Lockridge
Promoter and transcription start site of human and rabbit butyrylcholinesterase genes.
The Journal of biological chemistry 1994;269(33):20829-37.
1994: Patrick Masson; Marie-Thérèse Froment; R C Sorenson; Cynthia F Bartels; Oksana Lockridge
Mutation His322Asn in human acetylcholinesterase does not alter electrophoretic and catalytic properties of the erythrocyte enzyme.
Blood 1994;83(10):3003-5.
1993: J R Huth; F Perini; Oksana Lockridge; Elliott Bedows; RW Ruddon
Protein folding and assembly in vitro parallel intracellular folding and assembly. Catalysis of folding and assembly of the human chorionic gonadotropin alpha beta dimer by protein disulfide isomerase.
The Journal of biological chemistry 1993;268(22):16472-82.
1993: Patrick Masson; S Adkins; Patrice Gouet; Oksana Lockridge
Recombinant human butyrylcholinesterase G390V, the fluoride-2 variant, expressed in Chinese hamster ovary cells, is a low affinity variant.
The Journal of biological chemistry 1993;268(19):14329-41.
1993: Cynthia F Bartels; T Zelinski; Oksana Lockridge
Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism.
American journal of human genetics 1993;52(5):928-36.
1992: C P Nogueira; Cynthia F Bartels; M C McGuire; S Adkins; T Lubrano; H M Rubinstein; H Lightstone; Abraham F L Van Der Spek; Oksana Lockridge; Bert N La Du
Identification of two different point mutations associated with the fluoride-resistant phenotype for human butyrylcholinesterase.
American journal of human genetics 1992;51(4):821-8.
1992: Cynthia F Bartels; FS Jensen; Oksana Lockridge; Abraham F L Van Der Spek; H M Rubinstein; T Lubrano; Bert N La Du
DNA mutation associated with the human butyrylcholinesterase K-variant and its linkage to the atypical variant mutation and other polymorphic sites.
American journal of human genetics 1992;50(5):1086-103.
1991: K Saito; Dennis J Thiele; M Davio; Oksana Lockridge; Vincent Massey
The cloning and expression of a gene encoding Old Yellow Enzyme from Saccharomyces carlsbergensis.
The Journal of biological chemistry 1991;266(31):20720-4.
1991: P W Allderdice; H A Gardner; D Galutira; Oksana Lockridge; B N LaDu; P J McAlpine
The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26.
Genomics 1991;11(2):452-4.
1991: P J McAlpine; M Dixon; P W Allderdice; Oksana Lockridge; B N La Du
The butyrylcholinesterase gene (BCHE) at 3q26.2 shows two RFLPs.
Nucleic acids research 1991;19(18):5088.
1991: Martine Arpagaus; Arnaud Chatonnet; Patrick Masson; M Newton; T A Vaughan; Cynthia F Bartels; C P Nogueira; Bert N La Du; Oksana Lockridge
Use of the polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates.
The Journal of biological chemistry 1991;266(11):6966-74.
1991: Bert N La Du; Cynthia F Bartels; C P Nogueira; Martine Arpagaus; Oksana Lockridge
Proposed nomenclature for human butyrylcholinesterase genetic variants identified by DNA sequencing.
Cellular and molecular neurobiology 1991;11(1):79-89.
1990: Bert N La Du; Cynthia F Bartels; C P Nogueira; Amiya K Hajra; H Lightstone; Abraham F L Van Der Spek; Oksana Lockridge
Phenotypic and molecular biological analysis of human butyrylcholinesterase variants.
Clinical biochemistry 1990;23(5):423-31.
1990: C P Nogueira; M C McGuire; C Graeser; Cynthia F Bartels; Martine Arpagaus; Abraham F L Van Der Spek; H Lightstone; Oksana Lockridge; Bert N La Du
Identification of a frameshift mutation responsible for the silent phenotype of human serum cholinesterase, Gly 117 (GGT----GGAG).
American journal of human genetics 1990;46(5):934-42.
1990: Patrick Masson; Arnaud Chatonnet; Oksana Lockridge
Evidence for a single butyrylcholinesterase gene in individuals carrying the C5 plasma cholinesterase variant (CHE2).
FEBS letters 1990;262(1):115-8.
1990: Martine Arpagaus; M Kott; K P Vatsis; Cynthia F Bartels; Bert N La Du; Oksana Lockridge
Structure of the gene for human butyrylcholinesterase. Evidence for a single copy.
Biochemistry 1990;29(1):124-31.
1990: Oksana Lockridge
Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine.
Pharmacology & therapeutics 1990;47(1):35-60.
1989: Arnaud Chatonnet; Oksana Lockridge
Comparison of butyrylcholinesterase and acetylcholinesterase.
The Biochemical journal 1989;260(3):625-34.
1989: M C McGuire; C P Nogueira; Cynthia F Bartels; H Lightstone; Amiya K Hajra; Abraham F L Van Der Spek; Oksana Lockridge; Bert N La Du
Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(3):953-7.
1988: Oksana Lockridge
Structure of human serum cholinesterase.
BioEssays : news and reviews in molecular, cellular and developmental biology 1988;9(4):125-8.
1987: C McTiernan; S Adkins; Arnaud Chatonnet; T A Vaughan; Cynthia F Bartels; M Kott; Terrone L Rosenberry; Bert N La Du; Oksana Lockridge
Brain cDNA clone for human cholinesterase.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6682-6.
1987: Oksana Lockridge; S Adkins; Bert N La Du
Location of disulfide bonds within the sequence of human serum cholinesterase.
The Journal of biological chemistry 1987;262(27):12945-52.
1987: Oksana Lockridge; Cynthia F Bartels; T A Vaughan; C K Wong; S E Norton; L L Johnson
Complete amino acid sequence of human serum cholinesterase.
The Journal of biological chemistry 1987;262(2):549-57.
1986: B N La Du; Oksana Lockridge
Molecular biology of human serum cholinesterase.
Federation proceedings 1986;45(13):2965-9.
1986: Oksana Lockridge; B N La Du
Amino acid sequence of the active site of human serum cholinesterase from usual, atypical, and atypical-silent genotypes.
Biochemical genetics 1986;24(5-6):485-98.
1983: H W Eckerson; A Oseroff; Oksana Lockridge; Bert N La Du
Immunological comparison of the usual and atypical human serum cholinesterase phenotypes.
Biochemical genetics 1983;21(1-2):93-108.
1982: Oksana Lockridge; B N La Du
Loss of the interchain disulfide peptide and dissociation of the tetramer following limited proteolysis of native human serum cholinesterase.
The Journal of biological chemistry 1982;257(20):12012-8.
1982: Oksana Lockridge
Substance P hydrolysis by human serum cholinesterase.
Journal of neurochemistry 1982;39(1):106-10.
1982: C Meyers; Oksana Lockridge; B N La Du
Hydrolysis of methylprednisolone acetate by human serum cholinesterase.
Drug metabolism and disposition: the biological fate of chemicals 1982;10(3):279-80.
1981: R J Valentino; Oksana Lockridge; H W Eckerson; Bert N La Du
Prediction of drug sensitivity in individuals with atypical serum cholinesterase based on in vitro biochemical studies.
Biochemical pharmacology 1981;30(12):1643-9.
1980: Oksana Lockridge; N Mottershaw-Jackson; H W Eckerson; Bert N La Du
Hydrolysis of diacetylmorphine (heroin) by human serum cholinesterase.
The Journal of pharmacology and experimental therapeutics 1980;215(1):1-8.
1979: Oksana Lockridge; H W Eckerson; B N La Du
Interchain disulfide bonds and subunit organization in human serum cholinesterase.
The Journal of biological chemistry 1979;254(17):8324-30.
1979: T J Poulton; F M James; Oksana Lockridge
Prolonged apnea following trimethaphan and succinylcholine.
Anesthesiology 1979;50(1):54-6.
1978: Oksana Lockridge; B N La Du
Comparison of atypical and usual human serum cholinesterase. Purification, number of active sites, substrate affinity, and turnover number.
The Journal of biological chemistry 1978;253(2):361-6.
1977: Oksana Lockridge; E B Spector; A D Bloom
Argininosuccinate synthetase activity in cultured human lymphocytes.
Biochemical genetics 1977;15(3-4):395-407.
1975: E B Spector; Oksana Lockridge; A D Bloom
Citrulline metabolism in normal and citrullinemic human lymphocyte lines.
Biochemical genetics 1975;13(7-8):471-85.
1973: C Walsh; Oksana Lockridge; V Massey; R Abeles
Studies on the mechanism of action of the flavoenzyme lactate oxidase. Oxidation and elimination with beta-chlorolactate.
The Journal of biological chemistry 1973;248(20):7049-54.
1972: Oksana Lockridge; V Massey; P A Sullivan
Mechanism of action of the flavoenzyme lactate oxidase.
The Journal of biological chemistry 1972;247(24):8097-106.
1972: C T Walsh; A Schonbrunn; Oksana Lockridge; V Massey; R H Abeles
Inactivation of a flavoprotein, lactate oxidase, by an acetylenic substrate.
The Journal of biological chemistry 1972;247(18):6004-6.
1971: L Lorand; Oksana Lockridge; L K Campbell; R Myhrman; J Bruner-Lorand
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