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Guido Posern

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Tatyana Novoyatleva; Chinmoy Patra; Guido Posern; Ralph Theo Schermuly; Yves Schymura; Frederic Strobl; Jakub M Swiercz; Astrid Wietelmann; Timothy S Zheng; Wiebke Janssen; Felix B Engel
Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction.
Karolina Błajecka; Laura Leitner; Marin Marinov; Guido Posern; Kristin Uth; Alexandre Arcaro
Phosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with Dbl.
Kristin Katsch; Guido Posern; Julia Steger; Jens-Christian Albrecht; Sarah Jill de Jong; Harald Genth; Brigitte Biesinger
Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip.

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All Publications

2013: Tatyana Novoyatleva; Chinmoy Patra; Guido Posern; Ralph Theo Schermuly; Yves Schymura; Frederic Strobl; Jakub M Swiercz; Astrid Wietelmann; Timothy S Zheng; Wiebke Janssen; Felix B Engel
Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction.
Basic research in cardiology 2013;108(2):325.
2012: Karolina Błajecka; Laura Leitner; Marin Marinov; Guido Posern; Kristin Uth; Alexandre Arcaro
Phosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with Dbl.
PloS one 2012;7(9):e44945.
2012: Kristin Katsch; Guido Posern; Julia Steger; Jens-Christian Albrecht; Sarah Jill de Jong; Harald Genth; Brigitte Biesinger
Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip.
Cell communication and signaling : CCS 2012;10(1):5.
2012: Dmitry Shaposhnikov; Johannes Schilling; Arnaud Descot; Guido Posern
Myocardin-related transcription factor A regulates expression of Bok and Noxa and is involved in apoptotic signalling.
Cell cycle (Georgetown, Tex.) 2012;11(1):141-50.
2011: Laura Leitner; Alexander Mengel; Arnaud Descot; Reinhard Hoffmann; Sylvia Julien; Dmitry Shaposhnikov; Guido Posern
MAL/MRTF-A controls migration of non-invasive cells by upregulation of cytoskeleton-associated proteins.
Journal of cell science 2011;124(Pt 24):4318-31.
2011: Guido Posern
Should I stall or should I cycle? An inhibitor for Polo-like Kinase 1 with distinct roles in primary cells.
Cell cycle (Georgetown, Tex.) 2011;10(7):1029-30.
2011: Gang Liang; Kristofer Ahlqvist; Rajeswararao Pannem; Guido Posern; Ramin Massoumi
Serum response factor controls CYLD expression via MAPK signaling pathway.
PloS one 2011;6(5):e19613.
2010: CONSTANCE SMITH HICKS; BO XIAO; Rongkang Deng; Yifei Ji; Xia Zhao; Jason D Shepherd; Guido Posern; Dietmar Kuhl; Richard Huganir; David D Ginty; Paul F Worley; David J Linden
SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells.
Nature neuroscience 2010;13(9):1082-9.
2010: Stephan Busche; Elisabeth Kremmer; Guido Posern
E-cadherin regulates MAL-SRF-mediated transcription in epithelial cells.
Journal of cell science 2010;123(Pt 16):2803-9.
2010: Laura Leitner; Dmitry Shaposhnikov; Arnaud Descot; Reinhard Hoffmann; Guido Posern
Epithelial Protein Lost in Neoplasm alpha (Eplin-alpha) is transcriptionally regulated by G-actin and MAL/MRTF coactivators.
Molecular cancer 2010;9():60.
2009: Arnaud Descot; Reinhard Hoffmann; Dmitry Shaposhnikov; Markus Reschke; Axel Ullrich; Guido Posern
Negative regulation of the EGFR-MAPK cascade by actin-MAL-mediated Mig6/Errfi-1 induction.
Molecular cell 2009;35(3):291-304.
2009: Sina Stern; Evaine Debre; Christine Stritt; Jürgen Berger; Guido Posern; Bernd Knöll
A nuclear actin function regulates neuronal motility by serum response factor-dependent gene transcription.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(14):4512-8.
2008: Arnaud Descot; Monika Rex-Haffner; Geneviève Courtois; Dominique Bluteau; Antje Menssen; Thomas Mercher; Olivier A Bernard; Richard Treisman; Guido Posern
OTT-MAL is a deregulated activator of serum response factor-dependent gene expression.
Molecular and cellular biology 2008;28(20):6171-81.
2008: Stephan Busche; Arnaud Descot; Sylvia Julien; Harald Genth; Guido Posern
Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling.
Journal of cell science 2008;121(Pt 7):1025-35.
2007: Susanne Muehlich; Iwona Cicha; Christoph D. Garlichs; Bettina Krueger; Guido Posern; Margarete Goppelt-Struebe
Actin-dependent regulation of connective tissue growth factor.
American journal of physiology. Cell physiology 2007;292(5):C1732-8.
2006: Guido Posern; Richard Treisman
Actin' together: serum response factor, its cofactors and the link to signal transduction.
Trends in cell biology 2006;16(11):588-96.
2004: Guido Posern; Francesc Miralles; Sebastian Guettler; Richard Treisman
Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL.
The EMBO journal 2004;23(20):3973-83.
2003: Francesc Miralles; Guido Posern; Alexia-Ileana Zaromytidou; Richard Treisman
Actin dynamics control SRF activity by regulation of its coactivator MAL.
Cell 2003;113(3):329-42.
2002: Guido Posern; Athanassia Sotiropoulos; Richard Treisman
Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor.
Molecular biology of the cell 2002;13(12):4167-78.
2001: S Labunski; Guido Posern; Stephan Ludwig; G Kundt; Eva-B Bröcker; M Kunz
Tumour necrosis factor-alpha promoter polymorphism in erythema nodosum.
Acta dermato-venereologica 2001;81(1):18-21.
2000: M Schmidt; Matthias Goebeler; Guido Posern; Stephan M Feller; C S Seitz; Eva-Bettina Brocker; Ulf R Rapp; Stephan Ludwig
Ras-independent activation of the Raf/MEK/ERK pathway upon calcium-induced differentiation of keratinocytes.
The Journal of biological chemistry 2000;275(52):41011-7.
2000: Guido Posern; Ulf R Rapp; Stephan M Feller
The Crk signaling pathway contributes to the bombesin-induced activation of the small GTPase Rap1 in Swiss 3T3 cells.
Oncogene 2000;19(54):6361-8.
2000: Christian Kardinal; B Konkol; A Schulz; Guido Posern; H Lin; Knut Adermann; M Eulitz; Z Estrov; Moshe Talpaz; R B Arlinghaus; Stephan M Feller
Cell-penetrating SH3 domain blocker peptides inhibit proliferation of primary blast cells from CML patients.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(11):1529-38.
2000: Guido Posern; Rainer Saffrich; W Ansorge; Stephan M Feller
Rapid lamellipodia formation in nerve growth factor-stimulated PC12 cells is dependent on Rac and PI3K activity.
Journal of cellular physiology 2000;183(3):416-24.
2000: D Sakkab; Marc Lewitzky; Guido Posern; Ute Schaeper; Martin Sachs; Walter Birchmeier; Stephan M Feller
Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL.
The Journal of biological chemistry 2000;275(15):10772-8.
2000: Jan Voss; Guido Posern; JR Hannemann; LM Wiedemann; A G Turhan; Hélène A Poirel; Olivier A Bernard; Knut Adermann; Christian Kardinal; Stephan M Feller
The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways.
Oncogene 2000;19(13):1684-90.
1999: Christian Kardinal; Guido Posern; J Zheng; BS Knudsen; Ismail Moarefi; Stephan M Feller
Rational development of cell-penetrating high affinity SH3 domain binding peptides that selectively disrupt the signal transduction of Crk family adapters. Amgen Peptide Technology Group.
Annals of the New York Academy of Sciences 1999;886():289-92.
1998: Stephan M Feller; Guido Posern; Jan Voss; Christian Kardinal; D Sakkab; J Zheng; BS Knudsen
Physiological signals and oncogenesis mediated through Crk family adapter proteins.
Journal of cellular physiology 1998;177(4):535-52.
1998: F Schaper; Sabine Kirchhoff; Guido Posern; Mario Köster; André Oumard; Rekefet Sharf; Ben-Zion Levi; Hansjörg Hauser
Functional domains of interferon regulatory factor I (IRF-1).
The Biochemical journal 1998;335 ( Pt 1)():147-57.
1998: Guido Posern; Christoph K Weber; Ulf R Rapp; Stephan M Feller
Activity of Rap1 is regulated by bombesin, cell adhesion, and cell density in NIH3T3 fibroblasts.
The Journal of biological chemistry 1998;273(38):24297-300.
1998: Guido Posern; J Zheng; BS Knudsen; Christian Kardinal; K B Müller; Jan Voss; T Shishido; David Cowburn; G Cheng; B Wang; Gary Kruh; S K Burrell; C A Jacobson; D M Lenz; TJ Zamborelli; Knut Adermann; H Hanafusa; Stephan M Feller
Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G.
Oncogene 1998;16(15):1903-12.