FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Harald Schmidt

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Endothelium, Vascular

Physiology

Disorders

Vasodilation

Co-author Network

Publications

TOP 3
Rinrada Kietadisorn; Harald Schmidt; An L Moens
Folic Acid as a cardiovascular drug: dose matters.
Sven Wind; Knut Beuerlein; Melanie E Armitage; Ashraf Taye; Arun H S Kumar; Daniel Janowitz; Christina Neff; Ajay M Shah; Kirstin Wingler; Harald Schmidt
Oxidative stress and endothelial dysfunction in aortas of aged spontaneously hypertensive rats by NOX1/2 is reversed by NADPH oxidase inhibition.
Christoph Kleinschnitz; Henrike Grund; Kirstin Wingler; Melanie E Armitage; Emma Jones; Manish Mittal; David Barit; Tobias Schwarz; Christian Geis; Peter Kraft; Konstanze Barthel; Michael K Schuhmann; Alexander M Herrmann; Sven G Meuth; Guido Stoll; Sabine Meurer; Anja Schrewe; Lore Becker; Valérie Gailus-Durner; Helmut Fuchs; Thomas Klopstock; Martin Hrabé De Angelis; Karin Jandeleit-Dahm; Ajay M Shah; Norbert Weissmann; Harald Schmidt
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Harald Schmidt (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2010: Rinrada Kietadisorn; Harald Schmidt; An L Moens
Folic Acid as a cardiovascular drug: dose matters.
The American journal of cardiology 2010;106(11):1673-4.
2010: Sven Wind; Knut Beuerlein; Melanie E Armitage; Ashraf Taye; Arun H S Kumar; Daniel Janowitz; Christina Neff; Ajay M Shah; Kirstin Wingler; Harald Schmidt
Oxidative stress and endothelial dysfunction in aortas of aged spontaneously hypertensive rats by NOX1/2 is reversed by NADPH oxidase inhibition.
Hypertension 2010;56(3):490-7.
2010: Christoph Kleinschnitz; Henrike Grund; Kirstin Wingler; Melanie E Armitage; Emma Jones; Manish Mittal; David Barit; Tobias Schwarz; Christian Geis; Peter Kraft; Konstanze Barthel; Michael K Schuhmann; Alexander M Herrmann; Sven G Meuth; Guido Stoll; Sabine Meurer; Anja Schrewe; Lore Becker; Valérie Gailus-Durner; Helmut Fuchs; Thomas Klopstock; Martin Hrabé De Angelis; Karin Jandeleit-Dahm; Ajay M Shah; Norbert Weissmann; Harald Schmidt
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
PLoS biology 2010;8(9):.
2009: Melanie E Armitage; Kirstin Wingler; Harald Schmidt; Mylinh La
Translating the oxidative stress hypothesis into the clinic: NOX versus NOS.
Journal of molecular medicine (Berlin, Germany) 2009;87(11):1071-6.
2009: Kirstin Wingler; Harald Schmidt
Good stress, bad stress--the delicate balance in the vasculature.
Deutsches Ärzteblatt international 2009;106(42):677-84.
2009: Sabine Meurer; Sylke Pioch; Tatjana Pabst; Nils Opitz; Peter M Schmidt; Tobias Beckhaus; Kristina Wagner; Simone Matt; Kristina Gegenbauer; Sandra Geschka; Michael Karas; Johannes-Peter Stasch; Harald Schmidt; Werner Müller-Esterl
Nitric oxide-independent vasodilator rescues heme-oxidized soluble guanylate cyclase from proteasomal degradation.
Circulation research 2009;105(1):33-41.
2009: L S Hoffmann; P M Schmidt; Y Keim; S Schaefer; Harald Schmidt; J P Stasch
Distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation.
British journal of pharmacology 2009;157(5):781-95.
2009: Harald Schmidt; F Hofmann; J-P Stasch
Handbook of Experimental Pharmacology 191. cGMP: generators, effectors and therapeutic implications. Preface.
Handbook of experimental pharmacology 2009;(191):v-vi.
2009: Barbara Kemp-Harper; Harald Schmidt
cGMP in the vasculature.
Handbook of experimental pharmacology 2009;(191):447-67.
2009: Harald Schmidt; Peter M Schmidt; Johannes-Peter Stasch
NO- and haem-independent soluble guanylate cyclase activators.
Handbook of experimental pharmacology 2009;(191):309-39.
2008: Stavros Selemidis; Christopher G Sobey; Kirstin Wingler; Harald Schmidt; Grant R Drummond
NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition.
Pharmacology & therapeutics 2008;120(3):254-91.
2008: Sergey Dikalov; Anna Dikalova; Alfiya T Bikineyeva; Harald Schmidt; David G Harrison; Kathy K Griendling
Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production.
Free radical biology & medicine 2008;45(9):1340-51.
2008: Martín L Marro; Concepcion Peiro; Catherine M Panayiotou; Reshma S Baliga; Sabine Meurer; Harald Schmidt; Adrian J Hobbs
Characterization of the human alpha1 beta1 soluble guanylyl cyclase promoter: key role for NF-kappaB(p50) and CCAAT-binding factors in regulating expression of the nitric oxide receptor.
The Journal of biological chemistry 2008;283(29):20027-36.
2008: Sabine Heumüller; Sven Wind; Eduardo Barbosa-Sicard; Harald Schmidt; Rudi Busse; Katrin Schröder; Ralf P Brandes
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.
Hypertension 2008;51(2):211-7.
2008: Pavel I Nedvetsky; Sabine Meurer; Nils Opitz; Tatiana Y Nedvetskaya; Helmut Müller; Harald Schmidt
Heat shock protein 90 regulates stabilization rather than activation of soluble guanylate cyclase.
FEBS letters 2008;582(2):327-31.
2008: Mark Kirsch; Barbara Kemp-Harper; Norbert Weissmann; Friedrich Grimminger; Harald Schmidt
Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(1):30-40.
2007: Christiane Rothkegel; Peter M Schmidt; Derek-John Atkins; Linda Sarah Hoffmann; Harald Schmidt; Henning Schröder; Johannes-Peter Stasch
Dimerization region of soluble guanylate cyclase characterized by bimolecular fluorescence complementation in vivo.
Molecular pharmacology 2007;72(5):1181-90.
2007: Manish Mittal; Markus Roth; Peter König; Simone Hofmann; Eva Dony; Parag Goyal; Anne-Christin Selbitz; Ralph Theo Schermuly; Hossein A Ghofrani; Grazyna Kwapiszewska; Wolfgang Kummer; Walter Klepetko; Mir Ali Reza Hoda; Ludger Fink; Jörg Hänze; Werner Seeger; Friedrich Grimminger; Harald Schmidt; Norbert Weissmann
Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.
Circulation research 2007;101(3):258-67.
2007: Alyson A Miller; Grant R Drummond; Anja E Mast; Harald Schmidt; Christopher G Sobey
Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: role of estrogen.
Stroke; a journal of cerebral circulation 2007;38(7):2142-9.
2007: Julian Widder; Tomasz Guzik; Cornelius F H Mueller; Roza E Clempus; Harald Schmidt; Sergey Dikalov; Kathy K Griendling; Dean P Jones; David G Harrison
Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(4):762-8.
2007: Nils Opitz; Grant R Drummond; Stavros Selemidis; Sabine Meurer; Harald Schmidt
The 'A's and 'O's of NADPH oxidase regulation: a commentary on "Subcellular localization and function of alternatively spliced Noxo1 isoforms".
Free radical biology & medicine 2007;42(2):175-9.
2007: Roza E Clempus; Dan Sorescu; Anna Dikalova; Lily Pounkova; Patricia Jo; George P Sorescu; Harald Schmidt; Bernard Lassègue; Kathy K Griendling
Nox4 is required for maintenance of the differentiated vascular smooth muscle cell phenotype.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(1):42-8.
2006: Johannes-Peter Stasch; Peter M Schmidt; Pavel I Nedvetsky; Tatiana Y Nedvetskaya; Arun Kumar H S; Sabine Meurer; Martin Deile; Ashraf Taye; Andreas Knorr; Harald Lapp; Helmut Müller; Yagmur Turgay; Christiane Rothkegel; Adrian Tersteegen; Barbara Kemp-Harper; Werner Müller-Esterl; Harald Schmidt
Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels.
The Journal of clinical investigation 2006;116(9):2552-61.
2006: Oleg V Evgenov; Pal Pacher; Peter M Schmidt; György Haskó; Harald Schmidt; Johannes-Peter Stasch
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential.
Nature reviews. Drug discovery 2006;5(9):755-68.
2006: Christiane Rothkegel; Peter M Schmidt; Friederike Stoll; Henning Schröder; Harald Schmidt; Johannes-Peter Stasch
Identification of residues crucially involved in soluble guanylate cyclase activation.
FEBS letters 2006;580(17):4205-13.
2006: Claudia Stielow; Rusan A Catar; Gregor Muller; Kirstin Wingler; Peter Scheurer; Harald Schmidt; Henning Morawietz
Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells.
Biochemical and biophysical research communications 2006;344(1):200-5.
2005: Alyson A Miller; Grant R Drummond; Harald Schmidt; Christopher G Sobey
NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries.
Circulation research 2005;97(10):1055-62.
2005: Anna Dikalova; Roza E Clempus; Bernard Lassègue; Guangjie Cheng; James McCoy; Sergey Dikalov; Alejandra San Martin; Alicia N Lyle; David S Weber; Daiana Weiss; W. Robert Taylor; Harald Schmidt; Gary K Owens; David J. Lambeth; Kathy K Griendling
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice.
Circulation 2005;112(17):2668-76.
2005: Hans Matter; H S Arun Kumar; Roman Fedorov; Armin Frey; Peter Kotsonis; Elisabeth Hartmann; Lothar G Fröhlich; Andreas Reif; Wolfgang Pfleiderer; Peter Scheurer; Dipak K Ghosh; Ilme Schlichting; Harald Schmidt
Structural analysis of isoform-specific inhibitors targeting the tetrahydrobiopterin binding site of human nitric oxide synthases.
Journal of medicinal chemistry 2005;48(15):4783-92.
2005: Michael Kirchengast; Klaus Witte; Kerstin Stolpe; Lothar Schilling; Pavel I Nedvetsky; Harald Schmidt; Björn Lemmer
Effects of chronic endothelin ET(A) receptor blockade on blood pressure and vascular formation of cyclic guanosine-3',5'-monophosphate in spontaneously hypertensive rats.
Arzneimittel-Forschung 2005;55(9):498-504.
2005: Karine Laude; Hua Cai; Bruno Fink; Nyssa E Hoch; David S Weber; Louise McCann; Georg Kojda; Tohru Fukai; Harald Schmidt; Sergey Dikalov; Santhini Ramasamy; Graciela Gamez; Kathy K Griendling; David G Harrison
Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice.
American journal of physiology. Heart and circulatory physiology 2005;288(1):H7-12.
2004: Volker O Melichar; Delphine Behr-Roussel; Ulrike Zabel; L Otto Uttenthal; José Rodrigo; Alain Rupin; Tony J Verbeuren; Arun Kumar H S; Harald Schmidt
Reduced cGMP signaling associated with neointimal proliferation and vascular dysfunction in late-stage atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(47):16671-6.
2004: Rashmi K Ambasta; Pravir Kumar; Kathy K Griendling; Harald Schmidt; Rudi Busse; Ralf P Brandes
Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase.
The Journal of biological chemistry 2004;279(44):45935-41.
2004: Andreas Reif; ZV Shutenko; M Feelisch; Harald Schmidt
Superoxide dismutase and catalase are required to detect (.-)NO from both coupled and uncoupled neuronal no synthase.
Free radical biology & medicine 2004;37(7):988-97.
2004: Parag Goyal; Norbert Weissmann; Friedrich Grimminger; Cornelia Hegel; Lucius Bader; Frank Rose; Ludger Fink; Hossein A Ghofrani; Ralph Theo Schermuly; Harald Schmidt; Werner Seeger; Jörg Hänze
Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species.
Free radical biology & medicine 2004;36(10):1279-88.
2004: Jindong Ding; Alain Burette; Pavel I Nedvetsky; Harald Schmidt; Richard J Weinberg
Distribution of soluble guanylyl cyclase in the rat brain.
The Journal of comparative neurology 2004;472(4):437-48.
2004: Walee Chamulitrat; Wolfgang Stremmel; Tsukasa Kawahara; Kazuhito Rokutan; Hirotada Fujii; Kirstin Wingler; Harald Schmidt; Rainer Schmidt
A constitutive NADPH oxidase-like system containing gp91phox homologs in human keratinocytes.
The Journal of investigative dermatology 2004;122(4):1000-9.
2004: Kai G Kahl; Harald Schmidt; Stefan Jung; Paula Sherman; Klaus V Toyka; Jürgen Zielasek
Experimental autoimmune encephalomyelitis in mice with a targeted deletion of the inducible nitric oxide synthase gene: increased T-helper 1 response.
Neuroscience letters 2004;358(1):58-62.
2003: Kai G Kahl; Jürgen Zielasek; L Otto Uttenthal; José Rodrigo; Klaus V Toyka; Harald Schmidt
Protective role of the cytokine-inducible isoform of nitric oxide synthase induction and nitrosative stress in experimental autoimmune encephalomyelitis of the DA rat.
Journal of neuroscience research 2003;73(2):198-205.
2003: Reinhard Schneider; Ulrike Raff; Nicole Vornberger; Monika Schmidt; Ralf Freund; Mark Reber; Lothar Schramm; Stepan Gambaryan; Christoph Wanner; Harald Schmidt; Jan Galle
L-Arginine counteracts nitric oxide deficiency and improves the recovery phase of ischemic acute renal failure in rats.
Kidney international 2003;64(1):216-25.
2002: Pavel I Nedvetsky; William C Sessa; Harald Schmidt
There's NO binding like NOS binding: protein-protein interactions in NO/cGMP signaling.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16510-2.
2002: Alain Burette; Ulrike Zabel; Richard J Weinberg; Harald Schmidt; Juli G Valtschanoff
Synaptic localization of nitric oxide synthase and soluble guanylyl cyclase in the hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(20):8961-70.
2002: Pavel I Nedvetsky; Christoph Kleinschnitz; Harald Schmidt
Regional distribution of protein and activity of the nitric oxide receptor, soluble guanylyl cyclase, in rat brain suggests multiple mechanisms of regulation.
Brain research 2002;950(1-2):148-54.
2002: Stephanie Beer; Martin Reincke; Maike Kral; Su Zan Lie; Sonja Steinhauer; Harald Schmidt; Bruno Allolio; Stefan Neubauer
Susceptibility to cardiac ischemia/reperfusion injury is modulated by chronic estrogen status.
Journal of cardiovascular pharmacology 2002;40(3):420-8.
2002: Hans Matter; Peter Kotsonis; Otmar Klingler; Hartmut Strobel; Lothar G Fröhlich; Armin Frey; Wolfgang Pfleiderer; Harald Schmidt
Structural requirements for inhibition of the neuronal nitric oxide synthase (NOS-I): 3D-QSAR analysis of 4-oxo- and 4-amino-pteridine-based inhibitors.
Journal of medicinal chemistry 2002;45(14):2923-41.
2002: Lothar Schramm; Mylinh La; Ekkehart Heidbreder; Markus Hecker; Joe S Beckman; Kai Lopau; Josef Zimmermann; Johann Rendl; Christoph Reiners; Sabine Winderl; Christoph Wanner; Harald Schmidt
L-arginine deficiency and supplementation in experimental acute renal failure and in human kidney transplantation.
Kidney international 2002;61(4):1423-32.
2002: Ulrike Zabel; Christoph Kleinschnitz; Phil Oh; Pavel I Nedvetsky; Albert Smolenski; Helmut Müller; Petra Kronich; Peter Kugler; Ulrich Walter; Jan Schnitzer; Harald Schmidt
Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide.
Nature cell biology 2002;4(4):307-11.
2002: César Ibarra-Alvarado; Jan Galle; Volker O Melichar; Alexander Mameghani; Harald Schmidt
Phosphorylation of blood vessel vasodilator-stimulated phosphoprotein at serine 239 as a functional biochemical marker of endothelial nitric oxide/cyclic GMP signaling.
Molecular pharmacology 2002;61(2):312-9.
2002: Andrei M Komarov; Andreas Reif; Harald Schmidt
In vitro detection of nitric oxide and nitroxyl by electron paramagnetic resonance.
Methods in enzymology 2002;359():18-27.
2002: Hardi Lührs; Thomas Papadopoulos; Harald Schmidt; Thomas Menzel
Type I nitric oxide synthase in the human lung is predominantly expressed in capillary endothelial cells.
Respiration physiology 2002;129(3):367-74.
2001: Peter Kotsonis; Lothar G Fröhlich; C.S. Raman; H Li; M Berg; R Gerwig; V Groehn; Y Kang; N Al-Masoudi; S Taghavi-Moghadam; D Mohr; U Münch; J Schnabel; Pavel Martásek; Bettie Sue Masters; Hartmut Strobel; Thomas L Poulos; Hans Matter; Wolfgang Pfleiderer; Harald Schmidt
Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin.
The Journal of biological chemistry 2001;276(52):49133-41.
2001: M Vruwink; Harald Schmidt; Richard J Weinberg; Alain Burette
Substance P and nitric oxide signaling in cerebral cortex: anatomical evidence for reciprocal signaling between two classes of interneurons.
The Journal of comparative neurology 2001;441(4):288-301.
2001: K Wingler; S Wünsch; R Kreutz; Lars Rothermund; Martin Paul; Harald Schmidt
Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo.
Free radical biology & medicine 2001;31(11):1456-64.
2001: C Ibarra; Pavel I Nedvetsky; Manfred Gerlach; Peter Riederer; Harald Schmidt
Regional and age-dependent expression of the nitric oxide receptor, soluble guanylyl cyclase, in the human brain.
Brain research 2001;907(1-2):54-60.
2001: M M Pantke; Andreas Reif; Juli G Valtschanoff; ZV Shutenko; Armin Frey; Richard J Weinberg; Wolfgang Pfleiderer; Harald Schmidt
Pterin interactions with distinct reductase activities of NO synthase.
The Biochemical journal 2001;356(Pt 1):43-51.
2001: Andreas Reif; Luigi Zecca; Peter Riederer; M Feelisch; Harald Schmidt
Nitroxyl oxidizes NADPH in a superoxide dismutase inhibitable manner.
Free radical biology & medicine 2001;30(7):803-8.
2001: Alain Burette; Peter Petrusz; Harald Schmidt; Richard J Weinberg
Immunohistochemical localization of nitric oxide synthase and soluble guanylyl cyclase in the ventral cochlear nucleus of the rat.
The Journal of comparative neurology 2001;431(1):1-10.
2000: Peter Kotsonis; Lothar G Fröhlich; ZV Shutenko; R Horejsi; Wolfgang Pfleiderer; Harald Schmidt
Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide.
The Biochemical journal 2000;346 Pt 3():767-76.
2000: A M Komarov; D A Wink; M Feelisch; Harald Schmidt
Electron-paramagnetic resonance spectroscopy using N-methyl-D-glucamine dithiocarbamate iron cannot discriminate between nitric oxide and nitroxyl: implications for the detection of reaction products for nitric oxide synthase.
Free radical biology & medicine 2000;28(5):739-42.
2000: Elke Butt; M Bernhardt; Albert Smolenski; Peter Kotsonis; Lothar G Fröhlich; Albert Sickmann; Helmut E Meyer; Suzanne M Lohmann; Harald Schmidt
Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-dependent protein kinases.
The Journal of biological chemistry 2000;275(7):5179-87.
1999: S Hügel; Martin Reincke; Hinrik Strömer; J Winning; Michael Horn; Charlotte Dienesch; P Mora; Harald Schmidt; Bruno Allolio; Stefan Neubauer
Evidence against a role of physiological concentrations of estrogen in post-myocardial infarction remodeling.
Journal of the American College of Cardiology 1999;34(5):1427-34.
1999: Lothar G Fröhlich; Peter Kotsonis; H Traub; S Taghavi-Moghadam; N Al-Masoudi; H Hofmann; Hartmut Strobel; Hans Matter; Wolfgang Pfleiderer; Harald Schmidt
Inhibition of neuronal nitric oxide synthase by 4-amino pteridine derivatives: structure-activity relationship of antagonists of (6R)-5,6,7,8-tetrahydrobiopterin cofactor.
Journal of medicinal chemistry 1999;42(20):4108-21.
1999: A Frey; S Schneider-Rasp; U Marienfeld; J C Yu; Martin Paul; Wolfgang Poller; Harald Schmidt
Biochemical and functional characterization of nitric oxide synthase III gene transfer using a replication-deficient adenoviral vector.
Biochemical pharmacology 1999;58(7):1155-66.
1999: Hartmut Ruetten; U Zabel; Wolfgang Linz; Harald Schmidt
Downregulation of soluble guanylyl cyclase in young and aging spontaneously hypertensive rats.
Circulation research 1999;85(6):534-41.
1999: Kamen G Usunoff; Viktor Kharazia; Juli G Valtschanoff; Harald Schmidt; Richard J Weinberg
Nitric oxide synthase-containing projections to the ventrobasal thalamus in the rat.
Anatomy and embryology 1999;200(3):265-81.
1999: Andreas Reif; Lothar G Fröhlich; Peter Kotsonis; Armin Frey; Heike Bömmel; D A Wink; Wolfgang Pfleiderer; Harald Schmidt
Tetrahydrobiopterin inhibits monomerization and is consumed during catalysis in neuronal NO synthase.
The Journal of biological chemistry 1999;274(35):24921-9.
1999: M Feelisch; Peter Kotsonis; J Siebe; B Clement; Harald Schmidt
The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3,-a] quinoxalin-1-one is a nonselective heme protein inhibitor of nitric oxide synthase and other cytochrome P-450 enzymes involved in nitric oxide donor bioactivation.
Molecular pharmacology 1999;56(2):243-53.
1999: Ulrike Zabel; C Häusler; M Weeger; Harald Schmidt
Homodimerization of soluble guanylyl cyclase subunits. Dimerization analysis using a glutathione s-transferase affinity tag.
The Journal of biological chemistry 1999;274(26):18149-52.
1999: Peter Kotsonis; Armin Frey; Lothar G Fröhlich; H Hofmann; Andreas Reif; D A Wink; M Feelisch; Harald Schmidt
Autoinhibition of neuronal nitric oxide synthase: distinct effects of reactive nitrogen and oxygen species on enzyme activity.
The Biochemical journal 1999;340 ( Pt 3)():745-52.
1999: S Hügel; Stefan Neubauer; S Z Lie; R Ernst; Michael Horn; Harald Schmidt; Bruno Allolio; Martin Reincke
Multiple mechanisms are involved in the acute vasodilatory effect of 17beta-estradiol in the isolated perfused rat heart.
Journal of cardiovascular pharmacology 1999;33(6):852-8.
1999: Helga Stopper; Marianne Möller; Heike Bömmel; Harald Schmidt
Cytotoxic versus genotoxic effects of nitric oxide (NO).
Toxicology letters 1999;106(1):59-67.
1999: Jan Galle; U Zabel; U Hübner; A Hatzelmann; B Wagner; Christoph Wanner; Harald Schmidt
Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity.
British journal of pharmacology 1999;127(1):195-203.
1998: Heike Bömmel; Andreas Reif; Lothar G Fröhlich; Armin Frey; H Hofmann; D M Marecak; V Groehn; Peter Kotsonis; M La; S Köster; M Meinecke; M Bernhardt; M Weeger; Sandro Ghisla; G D Prestwich; Wolfgang Pfleiderer; Harald Schmidt
Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase.
The Journal of biological chemistry 1998;273(50):33142-9.
1998: Ulrike Zabel; M Weeger; M La; Harald Schmidt
Human soluble guanylate cyclase: functional expression and revised isoenzyme family.
The Biochemical journal 1998;335 ( Pt 1)():51-7.