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Ignazio Castagliuolo

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Chemicals & Drugs

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Reverse Transcriptase Polymerase Chain Reaction

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Margherita Festa; Renata Piccinini; Barbara Basso; Paola Brun; Ignazio Castagliuolo; Alfonso Zecconi
Staphylococcus aureus Efb protein expression in Nicotiana tabacum and immune response to oral administration.
Alessia Salvador; Daniela Vedaldi; Cristina Zuccato; Ilaria Lampronti; Eleonora Brognara; Paola Brun; Ignazio Castagliuolo; Roberto Gambari
Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts.
Paola Brun; Davide Carta; Ignazio Castagliuolo; Annalisa Dean; Valerio Di Marco; Pathak Surajit; Maria Grazia Ferlin
Peroxisome proliferator-activated receptor-γ mediates the anti-inflammatory effect of 3-hydroxy-4-pyridinecarboxylic acid derivatives: synthesis and biological evaluation.

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2013: Margherita Festa; Renata Piccinini; Barbara Basso; Paola Brun; Ignazio Castagliuolo; Alfonso Zecconi
Staphylococcus aureus Efb protein expression in Nicotiana tabacum and immune response to oral administration.
Research in veterinary science 2013;94(3):484-9.
2013: Alessia Salvador; Daniela Vedaldi; Cristina Zuccato; Ilaria Lampronti; Eleonora Brognara; Paola Brun; Ignazio Castagliuolo; Roberto Gambari
Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts.
Journal of photochemistry and photobiology. B, Biology 2013;121():57-66.
2013: Paola Brun; Davide Carta; Ignazio Castagliuolo; Annalisa Dean; Valerio Di Marco; Pathak Surajit; Maria Grazia Ferlin
Peroxisome proliferator-activated receptor-γ mediates the anti-inflammatory effect of 3-hydroxy-4-pyridinecarboxylic acid derivatives: synthesis and biological evaluation.
European journal of medicinal chemistry 2013;62():486-97.
2013: Paola Brun; Ignazio Castagliuolo; Alessandro Bagno; Valentina Battaglia; Francesca Ghezzo; G Iucci; Giovanni Marletta; Grazia M L Messina; Giorgio Palu; G Polzonetti; Michele Scorzeto; Stefano Sivolella; Stefano Vassanelli; Monica Dettin
Mechanisms underlying the attachment and spreading of human osteoblasts: from transient interactions to focal adhesions on vitronectin-grafted bioactive surfaces.
Acta biomaterialia 2013;9(4):6105-15.
2013: Romeo Romagnoli; Mojgan Aghazadeh Tabrizi; Pier Giovanni Baraldi; Marcella Bassetto; Giuseppe Basso; Roberta Bortolozzi; Andrea Brancale; Ignazio Castagliuolo; Ernest Hamel; Maria Kimatrai Salvador; Delia Preti; Giampietro Viola
Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents.
Journal of medicinal chemistry 2013;56(6):2606-18.
2013: Marco Scarpa; Giacomo Carlo Sturniolo; Marina Bortolami; Romilda Cardin; Ignazio Castagliuolo; Carlo Castoro; Renata D'Incà; Andromachi Kotsafti; Giorgia Maran; Marika Picciocchi; Anna Pozza; Cesare Ruffolo; Maria Cristina Scarpa; Imerio Angriman
Mucosal immune environment in colonic carcinogenesis: CD80 expression is associated to oxidative DNA damage and TLR4-NFκB signalling.
European journal of cancer (Oxford, England : 1990) 2013;49(1):254-63.
2012: Laurent Guillemot; Lionel Jond; Diego Martines; Daniela Pizzuti; Yann Schneider; Massimo Bongiovanni; Paola Brun; Ignazio Castagliuolo; Sandra Citi
Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury.
Journal of cell science 2012;125(Pt 21):5005-14.
2012: Roberta Danesin; Florian Delaunay; Paola Brun; Katya Brunelli; Ignazio Castagliuolo; Francesca Ghezzo; Giovanna Iucci; Michele Modesti; Martina Roso; Valérie Samouillan; Monica Dettin
Self-assembling peptide-enriched electrospun polycaprolactone scaffolds promote the h-osteoblast adhesion and modulate differentiation-associated gene expression.
Bone 2012;51(5):851-9.
2012: Paola Brun; Paola Brun; Romilda Cardin; Ignazio Castagliuolo; R Cavazzana; Velika Deligianni; E Martines; Silvia Spagnolo; Elena Tarricone; Paola Venier; Maria Vono; Matteo Zuin; Alvise La Gloria Valerio; Andrea Leonardi
Disinfection of ocular cells and tissues by atmospheric-pressure cold plasma.
PloS one 2012;7(3):e33245.
2012: Giampietro Viola; Roberta Bortolozzi; Paola Brun; Ignazio Castagliuolo; Maria Grazia Ferlin; Ernest Hamel; Stefano Moro; Giuseppe Basso
MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells.
Biochemical pharmacology 2012;83(1):16-26.
2011: Marco Scarpa; Melania Scarpa; Giacomo Carlo Sturniolo; Ignazio Castagliuolo; Renata D'Incà; Diego Faggian; Alessia Grillo; Mario Plebani; Anna Pozza; Cesare Ruffolo; Imerio Angriman
TLR2 and TLR4 up-regulation and colonization of the ileal mucosa by Clostridiaceae spp. in chronic/relapsing pouchitis.
The Journal of surgical research 2011;169(2):e145-54.
2011: Paola Barraja; Paola Brun; Libero Caracausi; Anna Carbone; Ignazio Castagliuolo; Francesco Dall'Acqua; Patrizia Diana; Alessandra Montalbano; Alessia Salvador; Silvia Tisi; Daniela Vedaldi; Girolamo Cirrincione
Pyrrolo[3,2-h]quinazolines as photochemotherapeutic agents.
ChemMedChem 2011;6(7):1238-48.
2011: Patrizia Diana; Olaf-Georg Issinger; Barbara Parrino; Alessia Salvador; Antonina Stagno; Daniela Vedaldi; Paola Barraja; Paola Brun; Anna Carbone; Ignazio Castagliuolo; Francesco Dall'Acqua; Girolamo Cirrincione
Synthesis of triazenoazaindoles: a new class of triazenes with antitumor activity.
ChemMedChem 2011;6(7):1291-9.
2011: Marco Scarpa; Elisa Bonello; Ignazio Castagliuolo; Renata D'Incà; Diego Faggian; Alessia Grillo; Cesare Ruffolo; Melania Scarpa; Imerio Angriman
Relationship between mucosa-associated microbiota and inflammatory parameters in the ileal pouch after restorative proctocolectomy for ulcerative colitis.
Surgery 2011;150(1):56-67.
2011: Giovanni Marzaro; Adriana Chilin; Adriano Guiotto; Eugenio Uriarte; Paola Brun; Ignazio Castagliuolo; Francesca Tonus; Humberto González Díaz
Using the TOPS-MODE approach to fit multi-target QSAR models for tyrosine kinases inhibitors.
European journal of medicinal chemistry 2011;46(6):2185-92.
2011: Paola Brun; Francesca Ghezzo; Martina Roso; Roberta Danesin; Giorgio Palù; Alessandro Bagno; Michele Modesti; Ignazio Castagliuolo; Monica Dettin
Electrospun scaffolds of self-assembling peptides with poly(ethylene oxide) for bone tissue engineering.
Acta biomaterialia 2011;7(6):2526-32.
2011: Andrea Porzionato; Marcin Rucinski; Veronica Macchi; Carla Stecco; Ignazio Castagliuolo; Ludwik K Malendowicz; Raffaele De Caro
Expression of leptin and leptin receptor isoforms in the rat and human carotid body.
Brain research 2011;1385():56-67.
2011: Renata D'Incà; Michela Barollo; Marco Scarpa; Alessia Rosaria Grillo; Paola Brun; Maria Grazia Vettorato; Ignazio Castagliuolo; Giacomo Carlo Sturniolo
Rectal administration of Lactobacillus casei DG modifies flora composition and Toll-like receptor expression in colonic mucosa of patients with mild ulcerative colitis.
Digestive diseases and sciences 2011;56(4):1178-87.
2011: Melania Scarpa; Alessia R Grillo; Paola Brun; Veronica Macchi; Annalisa Stefani; Sara Signori; Andrea Buda; Paolo Fabris; maria teresa giordani; Raffaele De Caro; Giorgio Palù; Ignazio Castagliuolo; Diego Martines
Snail1 transcription factor is a critical mediator of hepatic stellate cell activation following hepatic injury.
American journal of physiology. Gastrointestinal and liver physiology 2011;300(2):G316-26.
2010: luca Antonioli; Matteo Fornai; Rocchina Colucci; Narcisa Ghisu; Marco Tuccori; O Awwad; A Bin; C Zoppellaro; Ignazio Castagliuolo; R M Gaion; M C Giron; Corrado Blandizzi
Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation.
British journal of pharmacology 2010;161(4):856-71.
2010: Mateja Zemljic; Marjan Rupnik; Melania Scarpa; Gregor Anderluh; Gorgio Palù; Ignazio Castagliuolo
Repetitive domain of Clostridium difficile toxin B exhibits cytotoxic effects on human intestinal epithelial cells and decreases epithelial barrier function.
Anaerobe 2010;16(5):527-32.
2010: Maria Grazia Ferlin; Roberta Bortolozzi; Paola Brun; Ignazio Castagliuolo; Ernest Hamel; Giuseppe Basso; Giampietro Viola
Synthesis and in vitro evaluation of 3h-pyrrolo[3,2-f]-quinolin-9-one derivatives that show potent and selective anti-leukemic activity.
ChemMedChem 2010;5(8):1373-85.
2010: Paola Barraja; Libero Caracausi; Patrizia Diana; Anna Carbone; Alessandra Montalbano; Girolamo Cirrincione; Paola Brun; Giorgio Palù; Ignazio Castagliuolo; Francesco Dall'Acqua; Daniela Vedaldi; Alessia Salvador
Synthesis of pyrrolo[3,2-h]quinolinones with good photochemotherapeutic activity and no DNA damage.
Bioorganic & medicinal chemistry 2010;18(13):4830-43.
2010: Paola Brun; Maria Cecilia Giron; Chiara Zoppellaro; Anna Bin; Andrea Porzionato; Raffaele De Caro; Giovanni Barbara; Vincenzo Stanghellini; Roberto Corinaldesi; Giovanni Zaninotto; Giorgio Palù; Rosa Maria Gaion; Marcello Tonini; Roberto De Giorgio; Ignazio Castagliuolo
Herpes simplex virus type 1 infection of the rat enteric nervous system evokes small-bowel neuromuscular abnormalities.
Gastroenterology 2010;138(5):1790-801.
2010: Melania Scarpa; Renata Piccinini; Paola Brun; Alessia Grillo; Giorgio Palù; Carlo Mengoli; Valentina Daprà; Ignazio Castagliuolo; Alfonso Zecconi
Relationship between virulence factor genes in bovine Staphylococcus aureus subclinical mastitis isolates and binding to anti-adhesin antibodies.
The Journal of dairy research 2010;77(2):159-67.
2010: Stefano Dall'Acqua; Ignazio Castagliuolo; Paola Brun; Federica Ditadi; Giorgio Palù; Gabbriella Innocenti
Triterpene glycosides with in vitro anti-inflammatory activity from Cyclamen repandum tubers.
Carbohydrate research 2010;345(5):709-14.
2010: Stefano Comai; Stefano Dall'Acqua; Alessia Grillo; Ignazio Castagliuolo; Khilendra Gurung; Gabbriella Innocenti
Essential oil of Lindera neesiana fruit: chemical analysis and its potential use in topical applications.
Fitoterapia 2010;81(1):11-6.
2009: Annalisa Dean; Maria Grazia Ferlin; Paola Brun; Ignazio Castagliuolo; Robert A Yokel; Denis Badocco; Paolo Pastore; Alfonso Venzo; G Giorgio Bombi; Valerio B Di Marco
1,6-Dimethyl-4-hydroxy-3-pyridinecarboxylic acid and 4-hydroxy-2-methyl-3-pyridinecarboxylic acid as new possible chelating agents for iron and aluminium.
Dalton transactions (Cambridge, England : 2003) 2009;(10):1815-24.
2009: Mirta Canevari; Ignazio Castagliuolo; Paola Brun; M Cardin; Marco Schiavon; Gianfranco Pasut; Francesco M Veronese
Poly(ethylene glycol)-mesalazine conjugate for colon specific delivery.
International journal of pharmaceutics 2009;368(1-2):171-7.
2009: Laura Meléndez-Alafort; Anna Nadali; Gianfranco Pasut; Elena Zangoni; Raffaele De Caro; Luca Cariolato; Maria Cecilia Giron; Ignazio Castagliuolo; Francesco M Veronese; Ulderico Mazzi
Detection of sites of infection in mice using 99mTc-labeled PN(2)S-PEG conjugated to UBI and 99mTc-UBI: a comparative biodistribution study.
Nuclear medicine and biology 2009;36(1):57-64.
2008: Lorena Giovagnini; Sergio Sitran; Ignazio Castagliuolo; Paola Brun; Maddalena Corsini; Piero Zanello; Alfonso Zoleo; Annalisa Maniero; Barbara Biondi; Dolores Fregona
Ru(III)-based compounds with sulfur donor ligands: synthesis, characterization, electrochemical behaviour and anticancer activity.
Dalton transactions (Cambridge, England : 2003) 2008;(47):6699-708.
2008: Sandra Voltan; Diego Martines; Marina Elli; Paola Brun; Stefano Longo; Andrea Porzionato; Veronica Macchi; Renata D'Incà; Melania Scarpa; Giorgio Palù; Giacomo C Sturniolo; Lorenzo Morelli; Ignazio Castagliuolo
Lactobacillus crispatus M247-derived H2O2 acts as a signal transducing molecule activating peroxisome proliferator activated receptor-gamma in the intestinal mucosa.
Gastroenterology 2008;135(4):1216-27.
2008: Sergio Caffieri; Stefano Dall'Acqua; Ignazio Castagliuolo; Paola Brun; Giorgia Miolo
UVB photolysis of hydrocortisone 21-acetate.
Journal of pharmaceutical and biomedical analysis 2008;47(4-5):771-7.
2008: Monica Facco; Paola Brun; Ilenia Baesso; Mario Costantini; Christian Rizzetto; Alessandro Berto; Nicola Baldan; Giorgio Palù; Gianpietro Semenzato; Ignazio Castagliuolo; Giovanni Zaninotto
T cells in the myenteric plexus of achalasia patients show a skewed TCR repertoire and react to HSV-1 antigens.
The American journal of gastroenterology 2008;103(7):1598-609.
2008: Paola Brun; Melania Scarpa; Alessia Grillo; Giorgio Palù; Carlo Mengoli; Alfonso Zecconi; Patrizia Spigaglia; Paola Mastrantonio; Ignazio Castagliuolo
Clostridium difficile TxAC314 and SLP-36kDa enhance the immune response toward a co-administered antigen.
Journal of medical microbiology 2008;57(Pt 6):725-31.
2008: Annalisa Dean; Maria Grazia Ferlin; Paola Brun; Ignazio Castagliuolo; Denis Badocco; Paolo Pastore; Alfonso Venzo; G Giorgio Bombi; Valerio B Di Marco
Evaluation of 2-methyl-3-hydroxy-4-pyridinecarboxylic acid as a possible chelating agent for iron and aluminium.
Dalton transactions (Cambridge, England : 2003) 2008;(13):1689-97.
2008: Paola Brun; Antonella Zumbo; Ignazio Castagliuolo; Giovanni Delogu; Filippo Manfrin; Michela Sali; Giovanni Fadda; Catherine Grillot-Courvalin; Giorgio Palù; Riccardo Manganelli
Intranasal delivery of DNA encoding antigens of Mycobacterium tuberculosis by non-pathogenic invasive Escherichia coli.
Vaccine 2008;26(16):1934-41.
2007: Venusia Gasparotto; Ignazio Castagliuolo; Maria Grazia Ferlin
3-substituted 7-phenyl-pyrroloquinolinones show potent cytotoxic activity in human cancer cell lines.
Journal of medicinal chemistry 2007;50(22):5509-13.
2007: Alessandro Bagno; Alessandro Piovan; Monica Dettin; Paola Brun; Roberta Gambaretto; Giorgio Palù; Carlo Di Bello; Ignazio Castagliuolo
Improvement of Anselme's adhesion model for evaluating human osteoblast response to peptide-grafted titanium surfaces.
Bone 2007;41(4):704-12.
2007: Sandra Voltan; Ignazio Castagliuolo; Marina Elli; Stefano Longo; Paola Brun; Renata D'Incà; Andrea Porzionato; Veronica Macchi; Giorgio Palù; Giacomo Carlo Sturniolo; Lorenzo Morelli; Diego Martines
Aggregating phenotype in Lactobacillus crispatus determines intestinal colonization and TLR2 and TLR4 modulation in murine colonic mucosa.
Clinical and vaccine immunology : CVI 2007;14(9):1138-48.
2007: Laura Martelli; Eugenio Ragazzi; Francesco Di Mario; Maurizio Martelli; Ignazio Castagliuolo; M Dal Maschio; G Palù; M Maschietto; M Scorzeto; S Vassanelli; Paola Brun
A potential role for the vanilloid receptor TRPV1 in the therapeutic effect of curcumin in dinitrobenzene sulphonic acid-induced colitis in mice.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2007;19(8):668-74.
2007: Alessandro Bagno; Alessandro Piovan; Monica Dettin; Alessia Chiarion; Paola Brun; Roberta Gambaretto; Giovanni Fontana; Carlo Di Bello; Giorgio Palù; Ignazio Castagliuolo
Human osteoblast-like cell adhesion on titanium substrates covalently functionalized with synthetic peptides.
Bone 2007;40(3):693-9.
2007: Paola Brun; Ignazio Castagliuolo; Vincenza Di Leo; Andrea Buda; Massimo Pinzani; Giorgio Palù; Diego Martines
Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(2):G518-25.
2006: P Brun; Ignazio Castagliuolo; A R Floreani; Andrea Buda; L Blasone; G Palù; Diego Martines
Increased risk of NASH in patients carrying the C(-159)T polymorphism in the CD14 gene promoter region.
Gut 2006;55(8):1212.
2006: Ignazio Castagliuolo; Renata Piccinini; Elisa Beggiao; Giorgio Palù; Carlo Mengoli; Federica Ditadi; Gaddo Vicenzoni; Alfonso Zecconi
Mucosal genetic immunization against four adhesins protects against Staphylococcus aureus-induced mastitis in mice.
Vaccine 2006;24(20):4393-402.
2006: Venusia Gasparotto; Ignazio Castagliuolo; Gianfranco Chiarelotto; Vincenzo Pezzi; Daniela Montanaro; Paola Brun; Giorgio Palù; Giampietro Viola; Maria Grazia Ferlin
Synthesis and biological activity of 7-phenyl-6,9-dihydro-3H-pyrrolo[3,2-f]quinolin-9-ones: a new class of antimitotic agents devoid of aromatase activity.
Journal of medicinal chemistry 2006;49(6):1910-5.
2005: Paola Brun; Ignazio Castagliuolo; Massimo Pinzani; Giorgio Palù; Diego Martines
Exposure to bacterial cell wall products triggers an inflammatory phenotype in hepatic stellate cells.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(3):G571-8.
2005: Ignazio Castagliuolo; Elisa Beggiao; Paola Brun; Luisa Barzon; Sylvie Goussard; Riccardo Manganelli; Catherine Grillot-Courvalin; Giorgio Palù
Engineered E. coli delivers therapeutic genes to the colonic mucosa.
Gene therapy 2005;12(13):1070-8.
2005: Maria Grazia Ferlin; Gianfranco Chiarelotto; Venusia Gasparotto; Lisa Dalla Via; Vincenzo Pezzi; Luisa Barzon; Giorgio Palù; Ignazio Castagliuolo
Synthesis and in vitro and in vivo antitumor activity of 2-phenylpyrroloquinolin-4-ones.
Journal of medicinal chemistry 2005;48(9):3417-27.
2005: Anna-Lisa Stefani; Luisa Barzon; Ignazio Castagliuolo; Maria Guido; Monia Pacenti; Cristina Parolin; Fabio Farinati; Giorgio Palù
Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma.
Journal of hepatology 2005;42(5):728-35.
2005: Paola Brun; Cristina Mastrotto; Elisa Beggiao; Annalisa Stefani; Luisa Barzon; Giacomo Carlo Sturniolo; Giorgio Palù; Ignazio Castagliuolo
Neuropeptide neurotensin stimulates intestinal wound healing following chronic intestinal inflammation.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(4):G621-9.
2005: Luisa Barzon; Elisa Gnatta; Ignazio Castagliuolo; Marta Trevisan; Fabiola Moretti; Alfredo Pontecorvi; Marco Boscaro; Giorgio Palù
Modulation of retrovirally driven therapeutic genes by mutant TP53 in anaplastic thyroid carcinoma.
Cancer gene therapy 2005;12(4):381-8.
2005: Ignazio Castagliuolo; Francesca Galeazzi; Susanna Ferrari; Marina Elli; Paola Brun; Andrea Cavaggioni; Deborah Tormen; Giacomo Carlo Sturniolo; Lorenzo Morelli; Giorgio Palù
Beneficial effect of auto-aggregating Lactobacillus crispatus on experimentally induced colitis in mice.
FEMS immunology and medical microbiology 2005;43(2):197-204.
2004: Ignazio Castagliuolo; Marina Sardina; Paola Brun; Chiara DeRos; Cristina Mastrotto; Laura Lovato; Giorgio Palù
Clostridium difficile toxin A carboxyl-terminus peptide lacking ADP-ribosyltransferase activity acts as a mucosal adjuvant.
Infection and immunity 2004;72(5):2827-36.
2004: Ignazio Castagliuolo; Paola Brun; Mario Costantini; Christian Rizzetto; Giorgio Palù; Michela Costantino; Nicola Baldan; Giovanni Zaninotto
Esophageal achalasia: is the herpes simplex virus really innocent?
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2004;8(1):24-30; discussion 30.
2003: Ignazio Castagliuolo; Paola Brun; Deborah Tormen; Giorgio Palò
Lymphocytes endowed with colon-selective homing and engineered to produce TGF-beta1 prevent the development of dinitrobenzene sulphonic acid colitis.
European journal of gastroenterology & hepatology 2003;15(12):1257-65.
2003: Simos Simeonidis; Ignazio Castagliuolo; Amy Pan; Jennifer Liu; Chi-Chi Wang; Andreas Mykoniatis; Asia Pasha; Leyla Valenick; Stavros Sougioultzis; Dezheng Zhao; Charalabos Pothoulakis
Regulation of the NK-1 receptor gene expression in human macrophage cells via an NF-kappa B site on its promoter.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2957-62.
2003: Luisa Barzon; Roberta Bonaguro; Ignazio Castagliuolo; Marco Chilosi; Elisa Franchin; Claudia Del Vecchio; Ilaria Giaretta; Marco Boscaro; Giorgio Palù
Gene therapy of thyroid cancer via retrovirally-driven combined expression of human interleukin-2 and herpes simplex virus thymidine kinase.
European journal of endocrinology / European Federation of Endocrine Societies 2003;148(1):73-80.
2002: Luisa Barzon; Roberta Bonaguro; Ignazio Castagliuolo; Marco Chilosi; Elisa Gnatta; Cristina Parolin; Marco Boscaro; Giorgio Palù
Transcriptionally targeted retroviral vector for combined suicide and immunomodulating gene therapy of thyroid cancer.
The Journal of clinical endocrinology and metabolism 2002;87(11):5304-11.
2002: Ignazio Castagliuolo; Olivier Morteau; Andrew C Keates; Leyla Valenick; Chi C Wang; Jeff Zacks; B Lu; Norma P Gerard; Charalabos Pothoulakis
Protective effects of neurokinin-1 receptor during colitis in mice: role of the epidermal growth factor receptor.
British journal of pharmacology 2002;136(2):271-9.
2002: Olivier Morteau; Ignazio Castagliuolo; Andreas Mykoniatis; Jeff Zacks; Michael Wlk; Bao Lu; Charalabos Pothoulakis; Norma P Gerard; Craig Gerard
Genetic deficiency in the chemokine receptor CCR1 protects against acute Clostridium difficile toxin A enteritis in mice.
Gastroenterology 2002;122(3):725-33.
2001: Ignazio Castagliuolo; Katia P Karalis; Leyla Valenick; Asia Pasha; ST Nikulasson; Michael Wlk; Charalabos Pothoulakis
Endogenous corticosteroids modulate Clostridium difficile toxin A-induced enteritis in rats.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(4):G539-45.
2000: Andrew C Keates; Ignazio Castagliuolo; W W Cruickshank; B Qiu; K O Arseneau; W Brazer; Ciarán P Kelly
Interleukin 16 is up-regulated in Crohn's disease and participates in TNBS colitis in mice.
Gastroenterology 2000;119(4):972-82.
2000: Ignazio Castagliuolo; Leyla Valenick; J Liu; Charalabos Pothoulakis
Epidermal growth factor receptor transactivation mediates substance P-induced mitogenic responses in U-373 MG cells.
The Journal of biological chemistry 2000;275(34):26545-50.
2000: Martin Riegler; Ignazio Castagliuolo; C Wang; Michael Wlk; T Sogukoglu; Etienne Wenzl; Jeffrey B Matthews; Charalabos Pothoulakis
Neurotensin stimulates Cl(-) secretion in human colonic mucosa In vitro: role of adenosine.
Gastroenterology 2000;119(2):348-57.
2000: Michel Warny; Andrew C Keates; Sarah Keates; Ignazio Castagliuolo; Jeff Zacks; Samer Aboudola; A Qamar; Charalabos Pothoulakis; J Thomas LaMont; Ciarán P Kelly
p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis.
The Journal of clinical investigation 2000;105(8):1147-56.
1999: Ignazio Castagliuolo; J Thomas LaMont
Pathophysiology, diagnosis and treatment of Clostridium difficile infection.
The Keio journal of medicine 1999;48(4):169-74.
1999: Martin Riegler; Ignazio Castagliuolo; Michael Wlk; Charalabos Pothoulakis
Substance P causes a chloride-dependent short-circuit current response in rabbit colonic mucosa in vitro.
Scandinavian journal of gastroenterology 1999;34(12):1203-11.
1999: Martin Riegler; Ignazio Castagliuolo; Peter So; M Lotz; C Wang; Michael Wlk; T Sogukoglu; Enrico P Cosentini; Georg Bischof; Gerhard Hamilton; Bela Teleky; Etienne Wenzl; Jeffrey B Matthews; Charalabos Pothoulakis
Effects of substance P on human colonic mucosa in vitro.
The American journal of physiology 1999;276(6 Pt 1):G1473-83.
1999: Martin Riegler; M Lotz; Cynthia L Sears; Charalabos Pothoulakis; Ignazio Castagliuolo; C C Wang; R Sedivy; T Sogukoglu; Enrico P Cosentini; Georg Bischof; Wolfgang Feil; Bela Teleky; Gerhard Hamilton; J Thomas LaMont; Etienne Wenzl
Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro.
Gut 1999;44(4):504-10.
1999: Ignazio Castagliuolo; Chi C Wang; Leyla Valenick; Asia Pasha; ST Nikulasson; R E Carraway; Charalabos Pothoulakis
Neurotensin is a proinflammatory neuropeptide in colonic inflammation.
The Journal of clinical investigation 1999;103(6):843-9.
1999: B Qiu; Charalabos Pothoulakis; Ignazio Castagliuolo; ST Nikulasson; J Thomas LaMont
Participation of reactive oxygen metabolites in Clostridium difficile toxin A-induced enteritis in rats.
The American journal of physiology 1999;276(2 Pt 1):G485-90.
1999: Ignazio Castagliuolo; Martin Riegler; Leyla Valenick; J Thomas LaMont; Charalabos Pothoulakis
Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa.
Infection and immunity 1999;67(1):302-7.
1998: Charalabos Pothoulakis; Ignazio Castagliuolo; SE Leeman; Chi C Wang; H Li; Brenda J Hoffman; E Mezey
Substance P receptor expression in intestinal epithelium in clostridium difficile toxin A enteritis in rats.
The American journal of physiology 1998;275(1 Pt 1):G68-75.
1998: Ignazio Castagliuolo; Andrew C Keates; Chi C Wang; Asia Pasha; Leyla Valenick; Ciarán P Kelly; ST Nikulasson; J Thomas LaMont; Charalabos Pothoulakis
Clostridium difficile toxin A stimulates macrophage-inflammatory protein-2 production in rat intestinal epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):6039-45.
1998: Ignazio Castagliuolo; BK Wershil; Katia P Karalis; Asia Pasha; ST Nikulasson; Charalabos Pothoulakis
Colonic mucin release in response to immobilization stress is mast cell dependent.
The American journal of physiology 1998;274(6 Pt 1):G1094-1100.
1998: Charalabos Pothoulakis; Ignazio Castagliuolo; SE Leeman
Neuroimmune mechanisms of intestinal responses to stress. Role of corticotropin-releasing factor and neurotensin.
Annals of the New York Academy of Sciences 1998;840():635-48.
1998: BK Wershil; Ignazio Castagliuolo; Charalabos Pothoulakis
Direct evidence of mast cell involvement in Clostridium difficile toxin A-induced enteritis in mice.
Gastroenterology 1998;114(5):956-64.
1998: Ignazio Castagliuolo; Martin Riegler; Asia Pasha; ST Nikulasson; B Lu; C Gerard; Norma P Gerard; Charalabos Pothoulakis
Neurokinin-1 (NK-1) receptor is required in Clostridium difficile- induced enteritis.
The Journal of clinical investigation 1998;101(8):1547-50.
1998: Andrew C Keates; Ignazio Castagliuolo; B Qiu; ST Nikulasson; A Sengupta; Charalabos Pothoulakis
CGRP upregulation in dorsal root ganglia and ileal mucosa during Clostridium difficile toxin A-induced enteritis.
The American journal of physiology 1998;274(1 Pt 1):G196-202.
1997: Martin Riegler; Roland Sedivy; T Sogukoglu; Ignazio Castagliuolo; Charalabos Pothoulakis; Enrico P Cosentini; Georg Bischof; Gerhard Hamilton; Bela Teleky; Wolfgang Feil; J Thomas LaMont; Etienne Wenzl
Epidermal growth factor attenuates Clostridium difficile toxin A- and B-induced damage of human colonic mucosa.
The American journal of physiology 1997;273(5 Pt 1):G1014-22.
1997: J Salcedo; Sarah Keates; Charalabos Pothoulakis; Michel Warny; Ignazio Castagliuolo; J Thomas LaMont; Ciarán P Kelly
Intravenous immunoglobulin therapy for severe Clostridium difficile colitis.
Gut 1997;41(3):366-70.
1997: Ignazio Castagliuolo; Ciarán P Kelly; B S Qiu; ST Nikulasson; J Thomas LaMont; Charalabos Pothoulakis
IL-11 inhibits Clostridium difficile toxin A enterotoxicity in rat ileum.
The American journal of physiology 1997;273(2 Pt 1):G333-41.
1997: Ignazio Castagliuolo; Andrew C Keates; B Qiu; Ciarán P Kelly; ST Nikulasson; SE Leeman; Charalabos Pothoulakis
Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4788-93.
1997: Ciarán P Kelly; S Chetham; Sarah Keates; E F Bostwick; A M Roush; Ignazio Castagliuolo; J Thomas LaMont; Charalabos Pothoulakis
Survival of anti-Clostridium difficile bovine immunoglobulin concentrate in the human gastrointestinal tract.
Antimicrobial agents and chemotherapy 1997;41(2):236-41.
1996: Ignazio Castagliuolo; J Thomas LaMont; ST Nikulasson; Charalabos Pothoulakis
Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum.
Infection and immunity 1996;64(12):5225-32.
1996: Ignazio Castagliuolo; J Thomas LaMont; B Qiu; Sheila M Fleming; K Ramakrishnan Bhaskar; ST Nikulasson; Conan Kornetsky; Charalabos Pothoulakis
Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells.
The American journal of physiology 1996;271(5 Pt 1):G884-92.
1996: Ignazio Castagliuolo; S E Leeman; E Bartolak-Suki; ST Nikulasson; B Qiu; R E Carraway; Charalabos Pothoulakis
A neurotensin antagonist, SR 48692, inhibits colonic responses to immobilization stress in rats.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12611-5.
1996: Charalabos Pothoulakis; R J Gilbert; C Cladaras; Ignazio Castagliuolo; G Semenza; Y Hitti; J S Montcrief; J Linevsky; Ciarán P Kelly; ST Nikulasson; H P Desai; T D Wilkins; J Thomas LaMont
Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A.
The Journal of clinical investigation 1996;98(3):641-9.
1996: Ignazio Castagliuolo; J Thomas LaMont; B Qiu; ST Nikulasson; Charalabos Pothoulakis
A receptor decoy inhibits the enterotoxic effects of Clostridium difficile toxin A in rat ileum.
Gastroenterology 1996;111(2):433-8.
1996: B Qiu; Charalabos Pothoulakis; Ignazio Castagliuolo; Z Nikulasson; J Thomas LaMont
Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin.
Gastroenterology 1996;111(2):409-18.
1996: Charalabos Pothoulakis; U Galili; Ignazio Castagliuolo; Ciarán P Kelly; ST Nikulasson; Pradeep K Dudeja; T A Brasitus; J Thomas LaMont
A human antibody binds to alpha-galactose receptors and mimics the effects of Clostridium difficile toxin A in rat colon.
Gastroenterology 1996;110(6):1704-12.
1996: Ciarán P Kelly; Charalabos Pothoulakis; F Vavva; Ignazio Castagliuolo; E F Bostwick; J C O'Keane; Sarah Keates; J Thomas LaMont
Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotoxicity of C. difficile toxins.
Antimicrobial agents and chemotherapy 1996;40(2):373-9.
1994: Ignazio Castagliuolo; J Thomas LaMont; R Letourneau; C Kelly; J C O'Keane; A Jaffer; T C Theoharides; Charalabos Pothoulakis
Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum.
Gastroenterology 1994;107(3):657-65.
1994: Charalabos Pothoulakis; Ignazio Castagliuolo; J Thomas LaMont; A Jaffer; J C O'Keane; R M Snider; Susan E Leeman
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(3):947-51.
1993: Charalabos Pothoulakis; F Karmeli; Ciarán P Kelly; R Eliakim; M A Joshi; C J O'Keane; Ignazio Castagliuolo; J Thomas LaMont; D Rachmilewitz
Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum.
Gastroenterology 1993;105(3):701-7.
1993: Charalabos Pothoulakis; Ignazio Castagliuolo; J T LaMont
Diagnostic tests for Clostridium difficile diarrhoea and colitis: past, present and future.
Journal of gastroenterology and hepatology 1993;8(4):311-2.
1993: Charalabos Pothoulakis; Ciarán P Kelly; M A Joshi; N Gao; C J O'Keane; Ignazio Castagliuolo; J Thomas LaMont
Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum.
Gastroenterology 1993;104(4):1108-15.