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Risto Ala-Aho

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Chemicals & Drugs

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Publications

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Mervi J Toriseva; Risto Ala-Aho; Reidar Grénman; Juha Peltonen; Sirkku Peltonen; Veli-Matti Kähäri
Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells.
Mehdi Farshchian; Reidar Grénman; Ritva Heljasvaara; Markku Kallajoki; Atte Kivisaari; Juha Peltonen; Taina Pihlajaniemi; Pilvi Riihilä; Risto Ala-Aho; Veli-Matti Kähäri
Serpin peptidase inhibitor clade A member 1 (SerpinA1) is a novel biomarker for progression of cutaneous squamous cell carcinoma.
Hitoshi Endo; Johbu Itoh; Veli-Matti Kähäri; Kaori Kameyama; Maki Niioka; Isao Okazaki; Yoshihiko Sugioka; Risto Ala-Aho; Tetsu Watanabe
Matrix metalloproteinase-13 promotes recovery from experimental liver cirrhosis in rats.

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All Publications

2012: Mervi J Toriseva; Risto Ala-Aho; Reidar Grénman; Juha Peltonen; Sirkku Peltonen; Veli-Matti Kähäri
Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells.
PloS one 2012;7(3):e33041.
2011: Mehdi Farshchian; Reidar Grénman; Ritva Heljasvaara; Markku Kallajoki; Atte Kivisaari; Juha Peltonen; Taina Pihlajaniemi; Pilvi Riihilä; Risto Ala-Aho; Veli-Matti Kähäri
Serpin peptidase inhibitor clade A member 1 (SerpinA1) is a novel biomarker for progression of cutaneous squamous cell carcinoma.
The American journal of pathology 2011;179(3):1110-9.
2011: Hitoshi Endo; Johbu Itoh; Veli-Matti Kähäri; Kaori Kameyama; Maki Niioka; Isao Okazaki; Yoshihiko Sugioka; Risto Ala-Aho; Tetsu Watanabe
Matrix metalloproteinase-13 promotes recovery from experimental liver cirrhosis in rats.
Pathobiology : journal of immunopathology, molecular and cellular biology 2011;78(5):239-52.
2010: A K Kivisaari; Markku Kallajoki; Risto Ala-Aho; J A McGrath; Johann W Bauer; R Königová; M Medvecz; W Beckert; Reidar Grénman; Veli-Matti Kähäri
Matrix metalloproteinase-7 activates heparin-binding epidermal growth factor-like growth factor in cutaneous squamous cell carcinoma.
The British journal of dermatology 2010;163(4):726-35.
2010: Angela Stokes; Juho Joutsa; Risto Ala-Aho; Mark Pitchers; Caroline J Pennington; Craig Martin; Don J Premachandra; Yasunori Okada; Juha Peltonen; Reidar Grénman; Helen A James; Dylan R Edwards; Veli-Matti Kähäri
Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(7):2022-35.
2009: Veli-Matti Kähäri; Risto Ala-Aho
Stromal collagenase in melanoma: a vascular connection.
The Journal of investigative dermatology 2009;129(11):2545-7.
2009: Sari Suomela; Outi Elomaa; Tiina Skoog; Risto Ala-Aho; Leila Jeskanen; Jenita Pärssinen; Leena Latonen; Reidar Grénman; Juha Kere; Veli-Matti Kähäri; Ulpu Saarialho-Kere
CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.
PloS one 2009;4(6):e6030.
2008: Pia Vihinen; Risto Ala-Aho; Veli-Matti Kähäri
Diagnostic and prognostic role of matrix metalloproteases in cancer.
Expert opinion on medical diagnostics 2008;2(9):1025-39.
2007: Melissa R Junttila; Risto Ala-Aho; Terhi Jokilehto; Juha Peltonen; Markku Kallajoki; Reidar Grenman; Panu M Jaakkola; Jukka Westermarck; Veli-Matti Kähäri
p38alpha and p38delta mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells.
Oncogene 2007;26(36):5267-79.
2007: Melissa R Junttila; Pietri Puustinen; Minna Niemelä; Raija Ahola; Hugh Arnold; Trine Böttzauw; Risto Ala-Aho; Christina Nielsen; Johanna Ivaska; Yoichi Taya; Shi-Long Lu; Shujun Lin; Edward Chan; Xiao-Jing Wang; Reidar Grènman; Juergen Kast; Tuula Kallunki; Rosalie C Pelz; Veli-Matti Kähäri; Jukka Westermarck
CIP2A inhibits PP2A in human malignancies.
Cell 2007;130(1):51-62.
2007: Mervi J Toriseva; Risto Ala-Aho; Jarkko Karvinen; Andrew H Baker; Varpu S Marjomäki; Jyrki Heino; Veli-Matti Kähäri
Collagenase-3 (MMP-13) enhances remodeling of three-dimensional collagen and promotes survival of human skin fibroblasts.
The Journal of investigative dermatology 2007;127(1):49-59.
2006: Suvi-Katri Leivonen; Risto Ala-Aho; K Koli; Reidar Grénman; Juha Peltonen; Veli-Matti Kähäri
Activation of Smad signaling enhances collagenase-3 (MMP-13) expression and invasion of head and neck squamous carcinoma cells.
Oncogene 2006;25(18):2588-600.
2005: Pia Vihinen; Risto Ala-Aho; Veli-Matti Kähäri
Matrix metalloproteinases as therapeutic targets in cancer.
Current cancer drug targets 2005;5(3):203-20.
2005: Risto Ala-Aho; Veli-Matti Kähäri
Collagenases in cancer.
Biochimie 2005;87(3-4):273-86.
2004: Risto Ala-Aho; Matti Ahonen; Sarah George; Jari Heikkilä; Reidar Grénman; Markku Kallajoki; Veli-Matti Kähäri
Targeted inhibition of human collagenase-3 (MMP-13) expression inhibits squamous cell carcinoma growth in vivo.
Oncogene 2004;23(30):5111-23.
2004: Kirsi Joronen; Risto Ala-Aho; Marja-Leena Majuri; H Alenius; Veli-Matti Kähäri; Eero Vuorio
Adenovirus mediated intra-articular expression of collagenase-3 (MMP-13) induces inflammatory arthritis in mice.
Annals of the rheumatic diseases 2004;63(6):656-64.
2002: Erja Kerkelä; Risto Ala-Aho; Pekka Klemi; Seija Grénman; Steven D Shapiro; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
The Journal of pathology 2002;198(2):258-69.
2002: Matti Ahonen; Risto Ala-Aho; Andrew H Baker; Sarah George; Reidar Grénman; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):705-15.
2002: Risto Ala-Aho; Reidar Grénman; Prem Seth; Veli-Matti Kähäri
Adenoviral delivery of p53 gene suppresses expression of collagenase-3 (MMP-13) in squamous carcinoma cells.
Oncogene 2002;21(8):1187-95.
2002: Risto Ala-Aho; Nina Johansson; Andrew H Baker; Veli-Matti Kähäri
Expression of collagenase-3 (MMP-13) enhances invasion of human fibrosarcoma HT-1080 cells.
International journal of cancer. Journal international du cancer 2002;97(3):283-9.
2001: Erja Kerkelä; Risto Ala-Aho; Jouko Lohi; Reidar Grénman; V M-Kähäri; Ulpu Saarialho-Kere
Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers.
British journal of cancer 2001;84(5):659-69.
2000: Erja Kerkelä; Risto Ala-Aho; Leila Jeskanen; O Rechardt; Reidar Grénman; Steven D Shapiro; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
The Journal of investigative dermatology 2000;114(6):1113-9.
2000: Risto Ala-Aho; Nina Johansson; Reidar Grénman; N E Fusenig; Carlos López-Otín; Veli-Matti Kähäri
Inhibition of collagenase-3 (MMP-13) expression in transformed human keratinocytes by interferon-gamma is associated with activation of extracellular signal-regulated kinase-1,2 and STAT1.
Oncogene 2000;19(2):248-57.
2000: Nina Johansson; Risto Ala-Aho; Veli-Jukka Uitto; Reidar Grénman; N E Fusenig; Carlos López-Otín; Veli-Matti Kähäri
Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase.
Journal of cell science 2000;113 Pt 2():227-35.