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Thomas DeCoursey

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TOP 3
Boris Musset; Susan M E Smith; Sindhu Rajan; Vladimir V Cherny; Deri Morgan; Thomas DeCoursey
Oligomerization of the voltage-gated proton channel.
Boris Musset; Susan M E Smith; Sindhu Rajan; Vladimir V Cherny; Sukrutha Sujai; Deri Morgan; Thomas DeCoursey
Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating.
Melania Capasso; Mandeep K Bhamrah; Tom Henley; Robert S Boyd; C Langlais; Kelvin Cain; David Dinsdale; Karen Pulford; Mahmood Khan; Boris Musset; Vladimir V Cherny; Deri Morgan; Randy D Gascoyne; Elena Vigorito; Thomas DeCoursey; Ian C M MacLennan; Martin J S Dyer
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.

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All Publications

2010: Boris Musset; Susan M E Smith; Sindhu Rajan; Vladimir V Cherny; Deri Morgan; Thomas DeCoursey
Oligomerization of the voltage-gated proton channel.
Channels (Austin, Tex.) 2010;4(4):260-5.
2010: Boris Musset; Susan M E Smith; Sindhu Rajan; Vladimir V Cherny; Sukrutha Sujai; Deri Morgan; Thomas DeCoursey
Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating.
The Journal of physiology 2010;588(Pt 9):1435-49.
2010: Melania Capasso; Mandeep K Bhamrah; Tom Henley; Robert S Boyd; C Langlais; Kelvin Cain; David Dinsdale; Karen Pulford; Mahmood Khan; Boris Musset; Vladimir V Cherny; Deri Morgan; Randy D Gascoyne; Elena Vigorito; Thomas DeCoursey; Ian C M MacLennan; Martin J S Dyer
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.
Nature immunology 2010;11(3):265-72.
2010: Boris Musset; Melania Capasso; Vladimir V Cherny; Deri Morgan; Mandeep Bhamrah; Martin J S Dyer; Thomas DeCoursey
Identification of Thr29 as a critical phosphorylation site that activates the human proton channel Hvcn1 in leukocytes.
The Journal of biological chemistry 2010;285(8):5117-21.
2010: Thomas DeCoursey
Voltage-gated proton channels find their dream job managing the respiratory burst in phagocytes.
Physiology (Bethesda, Md.) 2010;25(1):27-40.
2009: Deri Morgan; Melania Capasso; Boris Musset; Vladimir V Cherny; Eduardo Ríos; Martin J S Dyer; Thomas DeCoursey
Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):18022-7.
2009: Thomas DeCoursey
Unintended consequences at NIH.
Science (New York, N.Y.) 2009;323(5911):209.
2009: Boris Musset; Vladimir V Cherny; Deri Morgan; Thomas DeCoursey
The intimate and mysterious relationship between proton channels and NADPH oxidase.
FEBS letters 2009;583(1):7-12.
2008: Thomas DeCoursey
Voltage-gated proton channels: what's next?
The Journal of physiology 2008;586(Pt 22):5305-24.
2008: Boris Musset; Deri Morgan; Vladimir V Cherny; Donald MacGlashan; Larry L Thomas; Eduardo Ríos; Thomas DeCoursey
A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):11020-5.
2008: Thomas DeCoursey
Voltage-gated proton channels.
Cellular and molecular life sciences : CMLS 2008;65(16):2554-73.
2008: B Musset; Vladimir V Cherny; Deri Morgan; Y Okamura; Scott Ramsey; D E Clapham; Thomas DeCoursey
Detailed comparison of expressed and native voltage-gated proton channel currents.
The Journal of physiology 2008;586(10):2477-86.
2007: Thomas DeCoursey
Electrophysiology of the phagocyte respiratory burst. Focus on "Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity".
American journal of physiology. Cell physiology 2007;293(1):C30-2.
2007: Deri Morgan; Vladimir V Cherny; Alison Finnegan; James Bollinger; Michael H Gelb; Thomas DeCoursey
Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity.
The Journal of physiology 2007;579(Pt 2):327-44.
2007: Deri Morgan; Thomas DeCoursey
Analysis of electrophysiological properties and responses of neutrophils.
Methods in molecular biology (Clifton, N.J.) 2007;412():139-75.
2007: Thomas DeCoursey; Vladimir V Cherny
Pharmacology of voltage-gated proton channels.
Current pharmaceutical design 2007;13(23):2400-20.
2006: Ricardo Murphy; Thomas DeCoursey
Charge compensation during the phagocyte respiratory burst.
Biochimica et biophysica acta 2006;1757(8):996-1011.
2006: Jon K Femling; Vladimir V Cherny; Deri Morgan; Balázs Rada; Alexandra Paige Volk; Gábor Czirják; Enyedi Peter; Sarah K England; Jessica G Moreland; Erzsébet Ligeti; William M Nauseef; Thomas DeCoursey
The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels.
The Journal of general physiology 2006;127(6):659-72.
2006: Thomas DeCoursey
It's difficult to publish contradictory findings.
Nature 2006;439(7078):784.
2005: Deri Morgan; Vladimir V Cherny; Ricardo Murphy; Ben Z Katz; Thomas DeCoursey
The pH dependence of NADPH oxidase in human eosinophils.
The Journal of physiology 2005;569(Pt 2):419-31.
2005: Thomas DeCoursey; Erzsébet Ligeti
Regulation and termination of NADPH oxidase activity.
Cellular and molecular life sciences : CMLS 2005;62(19-20):2173-93.
2005: Ricardo Murphy; Vladimir V Cherny; Deri Morgan; Thomas DeCoursey
Voltage-gated proton channels help regulate pHi in rat alveolar epithelium.
American journal of physiology. Lung cellular and molecular physiology 2005;288(2):L398-408.
2004: Thomas DeCoursey
During the respiratory burst, do phagocytes need proton channels or potassium channels, or both?
Science's STKE : signal transduction knowledge environment 2004;2004(233):pe21.
2003: Thomas DeCoursey
Interactions between NADPH oxidase and voltage-gated proton channels: why electron transport depends on proton transport.
FEBS letters 2003;555(1):57-61.
2003: Deri Morgan; Thomas DeCoursey
Diversity of voltage gated proton channels.
Frontiers in bioscience : a journal and virtual library 2003;8():s1266-79.
2003: Deri Morgan; Vladimir V Cherny; Ricardo Murphy; Wei Xu; Larry L Thomas; Thomas DeCoursey
Temperature dependence of NADPH oxidase in human eosinophils.
The Journal of physiology 2003;550(Pt 2):447-58.
2003: Vladimir V Cherny; Ricardo Murphy; Valerij Sokolov; Richard A Levis; Thomas DeCoursey
Properties of single voltage-gated proton channels in human eosinophils estimated by noise analysis and by direct measurement.
The Journal of general physiology 2003;121(6):615-28.
2003: Thomas DeCoursey; Deri Morgan; Vladimir V Cherny
The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels.
Nature 2003;422(6931):531-4.
2003: Thomas DeCoursey
Voltage-gated proton channels and other proton transfer pathways.
Physiological reviews 2003;83(2):475-579.
2002: Thomas DeCoursey; Deri Morgan; Vladimir V Cherny
The gp91phox component of NADPH oxidase is not a voltage-gated proton channel.
The Journal of general physiology 2002;120(6):773-9.
2002: Tom Schilling; Alexander Gratopp; Thomas DeCoursey; Claudia Eder
Voltage-activated proton currents in human lymphocytes.
The Journal of physiology 2002;545(Pt 1):93-105.
2002: Deri Morgan; Vladimir V Cherny; Marianne O Price; Mary C Dinauer; Thomas DeCoursey
Absence of proton channels in COS-7 cells expressing functional NADPH oxidase components.
The Journal of general physiology 2002;119(6):571-80.
2001: Thomas DeCoursey; Vladimir V Cherny; Deri Morgan; B Z Katz; M C Dinauer
The gp91phox component of NADPH oxidase is not the voltage-gated proton channel in phagocytes, but it helps.
The Journal of biological chemistry 2001;276(39):36063-6.
2001: Vladimir V Cherny; L M Henderson; Wei Xu; Larry L Thomas; Thomas DeCoursey
Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid.
The Journal of physiology 2001;535(Pt 3):783-94.
2001: Thomas DeCoursey; Vladimir V Cherny; A G DeCoursey; Wei Xu; Larry L Thomas
Interactions between NADPH oxidase-related proton and electron currents in human eosinophils.
The Journal of physiology 2001;535(Pt 3):767-81.
2001: Claudia Eder; Thomas DeCoursey
Voltage-gated proton channels in microglia.
Progress in neurobiology 2001;64(3):277-305.
2000: Tom Schilling; F N Quandt; Vladimir V Cherny; W Zhou; Uwe Heinemann; Thomas DeCoursey; Claudia Eder
Upregulation of Kv1.3 K(+) channels in microglia deactivated by TGF-beta.
American journal of physiology. Cell physiology 2000;279(4):C1123-34.
2000: Thomas DeCoursey; Vladimir V Cherny; W Zhou; Larry L Thomas
Simultaneous activation of NADPH oxidase-related proton and electron currents in human neutrophils.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6885-9.
2000: Thomas DeCoursey; Vladimir V Cherny
Common themes and problems of bioenergetics and voltage-gated proton channels.
Biochimica et biophysica acta 2000;1458(1):104-19.
2000: Thomas DeCoursey
Hypothesis: do voltage-gated H(+) channels in alveolar epithelial cells contribute to CO(2) elimination by the lung?
American journal of physiology. Cell physiology 2000;278(1):C1-C10.
1999: Vladimir V Cherny; Thomas DeCoursey
pH-dependent inhibition of voltage-gated H(+) currents in rat alveolar epithelial cells by Zn(2+) and other divalent cations.
The Journal of general physiology 1999;114(6):819-38.
1998: Thomas DeCoursey; Vladimir V Cherny
Temperature dependence of voltage-gated H+ currents in human neutrophils, rat alveolar epithelial cells, and mammalian phagocytes.
The Journal of general physiology 1998;112(4):503-22.
1998: Peter Pennefather; Wenjing Zhou; Thomas DeCoursey
Idiosyncratic gating of HERG-like K+ channels in microglia.
The Journal of general physiology 1998;111(6):795-805.
1998: W Zhou; Francisco S Cayabyab; Peter Pennefather; Lyanne C Schlichter; Thomas DeCoursey
HERG-like K+ channels in microglia.
The Journal of general physiology 1998;111(6):781-94.
1997: Thomas DeCoursey; Vladimir V Cherny
Deuterium isotope effects on permeation and gating of proton channels in rat alveolar epithelium.
The Journal of general physiology 1997;109(4):415-34.
1997: Vladimir V Cherny; L M Henderson; Thomas DeCoursey
Proton and chloride currents in Chinese hamster ovary cells.
Membrane & cell biology 1997;11(3):337-47.
1996: Thomas DeCoursey; S Y Kim; M R Silver; F N Quandt
Ion channel expression in PMA-differentiated human THP-1 macrophages.
The Journal of membrane biology 1996;152(2):141-57.
1996: Thomas DeCoursey; Vladimir V Cherny
Voltage-activated proton currents in human THP-1 monocytes.
The Journal of membrane biology 1996;152(2):131-40.
1996: S Y Kim; M R Silver; Thomas DeCoursey
Ion channels in human THP-1 monocytes.
The Journal of membrane biology 1996;152(2):117-30.
1996: Thomas DeCoursey; Vladimir V Cherny
Effects of buffer concentration on voltage-gated H+ currents: does diffusion limit the conductance?
Biophysical journal 1996;71(1):182-93.
1995: Thomas DeCoursey; Vladimir V Cherny
Voltage-activated proton currents in membrane patches of rat alveolar epithelial cells.
The Journal of physiology 1995;489 ( Pt 2)():299-307.
1995: Thomas DeCoursey
Mechanism of K+ channel block by verapamil and related compounds in rat alveolar epithelial cells.
The Journal of general physiology 1995;106(4):745-79.
1995: Vladimir V Cherny; V S Markin; Thomas DeCoursey
The voltage-activated hydrogen ion conductance in rat alveolar epithelial cells is determined by the pH gradient.
The Journal of general physiology 1995;105(6):861-96.
1994: Thomas DeCoursey; Vladimir V Cherny
Voltage-activated hydrogen ion currents.
The Journal of membrane biology 1994;141(3):203-23.
1994: Thomas DeCoursey; Vladimir V Cherny
Na(+)-H+ antiport detected through hydrogen ion currents in rat alveolar epithelial cells and human neutrophils.
The Journal of general physiology 1994;103(5):755-85.
1994: Peter Pennefather; Thomas DeCoursey
A scheme to account for the effects of Rb+ and K+ on inward rectifier K channels of bovine artery endothelial cells.
The Journal of general physiology 1994;103(4):549-81.
1994: M R Silver; Mark Shapiro; Thomas DeCoursey
Effects of external Rb+ on inward rectifier K+ channels of bovine pulmonary artery endothelial cells.
The Journal of general physiology 1994;103(4):519-48.
1993: Thomas DeCoursey; Vladimir V Cherny
Potential, pH, and arachidonate gate hydrogen ion currents in human neutrophils.
Biophysical journal 1993;65(4):1590-8.
1991: Thomas DeCoursey
Hydrogen ion currents in rat alveolar epithelial cells.
Biophysical journal 1991;60(5):1243-53.
1991: Mark Shapiro; Thomas DeCoursey
Permeant ion effects on the gating kinetics of the type L potassium channel in mouse lymphocytes.
The Journal of general physiology 1991;97(6):1251-78.
1991: Mark Shapiro; Thomas DeCoursey
Selectivity and gating of the type L potassium channel in mouse lymphocytes.
The Journal of general physiology 1991;97(6):1227-50.
1990: E R Jacobs; Thomas DeCoursey
Mechanisms of potassium channel block in rat alveolar epithelial cells.
The Journal of pharmacology and experimental therapeutics 1990;255(2):459-72.
1990: M R Silver; Thomas DeCoursey
Intrinsic gating of inward rectifier in bovine pulmonary artery endothelial cells in the presence or absence of internal Mg2+.
The Journal of general physiology 1990;96(1):109-33.
1990: Thomas DeCoursey
State-dependent inactivation of K+ currents in rat type II alveolar epithelial cells.
The Journal of general physiology 1990;95(4):617-46.
1989: E R Jacobs; Thomas DeCoursey
Ion channels in the metabolic regulation of respiratory cells.
Clinics in chest medicine 1989;10(1):25-36.
1988: Thomas DeCoursey; E R Jacobs; M R Silver
Potassium currents in rat type II alveolar epithelial cells.
The Journal of physiology 1988;395():487-505.
1987: Thomas DeCoursey; K G Chandy; S Gupta; Michael D Cahalan
Mitogen induction of ion channels in murine T lymphocytes.
The Journal of general physiology 1987;89(3):405-20.
1987: Thomas DeCoursey; K G Chandy; S Gupta; Michael D Cahalan
Two types of potassium channels in murine T lymphocytes.
The Journal of general physiology 1987;89(3):379-404.
1987: Michael D Cahalan; K G Chandy; Thomas DeCoursey; S Gupta; R S Lewis; J B Sutro
Ion channels in T lymphocytes.
Advances in experimental medicine and biology 1987;213():85-101.
1986: K G Chandy; Thomas DeCoursey; Michael Fischbach; N Talal; Michael D Cahalan; S Gupta
Altered K+ channel expression in abnormal T lymphocytes from mice with the lpr gene mutation.
Science (New York, N.Y.) 1986;233(4769):1197-200.
1985: Thomas DeCoursey; K G Chandy; S Gupta; M D Cahalan
Voltage-dependent ion channels in T-lymphocytes.
Journal of neuroimmunology 1985;10(1):71-95.
1985: K G Chandy; Thomas DeCoursey; Michael D Cahalan; S Gupta
Electroimmunology: the physiologic role of ion channels in the immune system.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(2 Suppl):787s-791s.
1985: Michael D Cahalan; K G Chandy; Thomas DeCoursey; S Gupta
A voltage-gated potassium channel in human T lymphocytes.
The Journal of physiology 1985;358():197-237.
1985: K G Chandy; Thomas DeCoursey; Michael D Cahalan; S Gupta
Ion channels in lymphocytes.
Journal of clinical immunology 1985;5(1):1-6.
1984: K G Chandy; Thomas DeCoursey; Michael D Cahalan; C McLaughlin; S Gupta
Voltage-gated potassium channels are required for human T lymphocyte activation.
The Journal of experimental medicine 1984;160(2):369-85.
1984: Thomas DeCoursey; O F Hutter
Potassium current noise induced by barium ions in frog skeletal muscle.
The Journal of physiology 1984;349():329-51.
1984: Thomas DeCoursey; John Dempster; O F Hutter
Inward rectifier current noise in frog skeletal muscle.
The Journal of physiology 1984;349():299-327.
1984: Thomas DeCoursey; K G Chandy; S Gupta; Michael D Cahalan
Voltage-gated K+ channels in human T lymphocytes: a role in mitogenesis?
Nature 1984;307(5950):465-8.
1982: Thomas DeCoursey; S H Bryant; R J Lipicky
Sodium currents in human skeletal muscle fibers.
Muscle & nerve 1982;5(8):614-8.
1981: Thomas DeCoursey; S H Bryant; K M Owenburg
Dependence of membrane potential on extracellular ionic concentrations in myotonic goats and rats.
The American journal of physiology 1981;240(1):C56-63.
1978: Thomas DeCoursey; Steven G Younkin; S H Bryant
Neural control of chloride conductance in rat extensor digitorum longus muscle.
Experimental neurology 1978;61(3):705-9.