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Johan teKoppele

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FJ Meyer; Kevin G Burnand; Said Abisi; Johan teKoppele; B van Els; Alberto Smith
Effect of collagen turnover and matrix metalloproteinase activity on healing of venous leg ulcers.
Guo-Feng Ma; Ahmed Ali; Nicole Verzijl; roeland hanemaaijer; Johan teKoppele; Yrjö T Konttinen; Jari Salo
Increased collagen degradation around loosened total hip replacement implants.
Ilja Tchetverikov; L S Lohmander; Nicole Verzijl; Tom W J Huizinga; Johan teKoppele; roeland hanemaaijer; Jeroen DeGroot
MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis.

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2008: FJ Meyer; Kevin G Burnand; Said Abisi; Johan teKoppele; B van Els; Alberto Smith
Effect of collagen turnover and matrix metalloproteinase activity on healing of venous leg ulcers.
The British journal of surgery 2008;95(3):319-25.
2006: Guo-Feng Ma; Ahmed Ali; Nicole Verzijl; roeland hanemaaijer; Johan teKoppele; Yrjö T Konttinen; Jari Salo
Increased collagen degradation around loosened total hip replacement implants.
Arthritis and rheumatism 2006;54(9):2928-33.
2005: Ilja Tchetverikov; L S Lohmander; Nicole Verzijl; Tom W J Huizinga; Johan teKoppele; roeland hanemaaijer; Jeroen DeGroot
MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis.
Annals of the rheumatic diseases 2005;64(5):694-8.
2004: Ilja Tchetverikov; H Karel Ronday; Benno van El; Geesje H Kiers; Nicole Verzijl; Johan teKoppele; Tom W J Huizinga; Jeroen DeGroot; roeland hanemaaijer
MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2004;63(7):881-3.
2004: Robert Landewé; Piet Geusens; Maarten Boers; Désirée van der Heijde; Willem F Lems; Johan teKoppele; Sjef van der Linden; Patrick Garnero
Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritis.
Arthritis and rheumatism 2004;50(5):1390-9.
2004: Jeroen DeGroot; Nicole Verzijl; Marion J G Wenting-van Wijk; Kim M G Jacobs; Benno van El; Peter M Van Roermund; Ruud A Bank; J W J Bijlsma; Johan teKoppele; Floris P J G Lafeber
Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis.
Arthritis and rheumatism 2004;50(4):1207-15.
2004: Jessica V Valencia; Stephen C Weldon; Douglas Quinn; Geesje H Kiers; Jeroen DeGroot; Johan teKoppele; Thomas Hughes
Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics.
Analytical biochemistry 2004;324(1):68-78.
2003: Ilja Tchetverikov; Nicole Verzijl; Tom W J Huizinga; Johan teKoppele; roeland hanemaaijer; Jeroen DeGroot
Active MMPs captured by alpha 2 macroglobulin as a marker of disease activity in rheumatoid arthritis.
Clinical and experimental rheumatology 2003;21(6):711-8.
2003: Ilja Tchetverikov; L R Lard; Jeroen DeGroot; Nicole Verzijl; Johan teKoppele; Ferdinand C Breedveld; Tom W J Huizinga; roeland hanemaaijer
Matrix metalloproteinases-3, -8, -9 as markers of disease activity and joint damage progression in early rheumatoid arthritis.
Annals of the rheumatic diseases 2003;62(11):1094-9.
2003: V N A Breeveld-Dwarkasing; Mieke de Boer-Brouwer; Johan teKoppele; Ruud A Bank; GC van der Weijden; MAM Taverne; F M F van Dissel-Emiliani
Regional differences in water content, collagen content, and collagen degradation in the cervix of nonpregnant cows.
Biology of reproduction 2003;69(5):1600-7.
2003: V N A Breeveld-Dwarkasing; Johan teKoppele; Ruud A Bank; GC van der Weijden; MAM Taverne; F M F van Dissel-Emiliani
Changes in water content, collagen degradation, collagen content, and concentration in repeated biopsies of the cervix of pregnant cows.
Biology of reproduction 2003;69(5):1608-14.
2003: Annemarie J van der Slot; Anne-Marie Zuurmond; Alfons F J Bardoel; Cisca Wijmenga; Hans E H Pruijs; David Sillence; Jürgen Brinckmann; David J Abraham; Carol M Black; Nicole Verzijl; Jeroen DeGroot; roeland hanemaaijer; Johan teKoppele; Tom W J Huizinga; Ruud A Bank
Identification of PLOD2 as telopeptide lysyl hydroxylase, an important enzyme in fibrosis.
The Journal of biological chemistry 2003;278(42):40967-72.
2003: Nicole Verzijl; Ruud A Bank; Johan teKoppele; Jeroen DeGroot
AGEing and osteoarthritis: a different perspective.
Current opinion in rheumatology 2003;15(5):616-22.
2003: Robert-Jan A N Lamers; Jeroen DeGroot; Elly J Spies-Faber; Renger Jellema; JIMMY MOLYNEUX; Nicole Verzijl; Johan teKoppele; Gerwin K Spijksma; Jack T W E Vogels; Jan van der Greef; Joop H J van Nesselrooij
Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic Guinea pigs.
The Journal of nutrition 2003;133(6):1776-80.
2003: Willemijn H van der Laan; H Karel Ronday; Johan teKoppele; Ferdinand C Breedveld; Tom W J Huizinga; Jan H Verheijen
No therapeutic effect of plasmin antagonist tranexamic acid in rheumatoid arthritis. A double-blind placebo-controlled pilot study.
Clinical and experimental rheumatology 2003;21(3):359-62.
2003: Shahin Hajizadeh; Jeroen DeGroot; Johan teKoppele; Andrej Tarkowski; L Vincent Collins
Extracellular mitochondrial DNA and oxidatively damaged DNA in synovial fluid of patients with rheumatoid arthritis.
Arthritis research & therapy 2003;5(5):R234-40.
2002: Albert C Chen; Michele M Temple; Darren M Ng; Nicole Verzijl; Jeroen DeGroot; Johan teKoppele; Robert Sah
Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage.
Arthritis and rheumatism 2002;46(12):3212-7.
2002: Janet L Huebner; Martha A Hanes; B Beekman; Johan teKoppele; JIMMY MOLYNEUX
A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(10):758-67.
2002: Jeroen DeGroot; Ruud A Bank; Ilja Tchetverikov; Nicole Verzijl; Johan teKoppele
Molecular markers for osteoarthritis: the road ahead.
Current opinion in rheumatology 2002;14(5):585-9.
2002: P A J Brama; Johan teKoppele; Ruud A Bank; Ab Barneveld; P René Van Weeren
Development of biochemical heterogeneity of articular cartilage: influences of age and exercise.
Equine veterinary journal 2002;34(3):265-9.
2002: Anne C A Marijnissen; Peter M Van Roermund; Nicole Verzijl; Johan teKoppele; J W J Bijlsma; Floris P J G Lafeber
Steady progression of osteoarthritic features in the canine groove model.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(4):282-9.
2002: P A J Brama; Johan teKoppele; Ruud A Bank; Ab Barneveld; P René Van Weeren
Biochemical development of subchondral bone from birth until age eleven months and the influence of physical activity.
Equine veterinary journal 2002;34(2):143-9.
2002: Anne C A Marijnissen; Peter M Van Roermund; Johan teKoppele; J W J Bijlsma; Floris P J G Lafeber
The canine 'groove' model, compared with the ACLT model of osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(2):145-55.
2002: Ruud A Bank; Nicole Verzijl; Floris P J G Lafeber; Johan teKoppele
Putative role of lysyl hydroxylation and pyridinoline cross-linking during adolescence in the occurrence of osteoarthritis at old age.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(2):127-34.
2002: Nicole Verzijl; Jeroen DeGroot; Zaken Chaya Ben; Orit Brau-Benjamin; Alice Maroudas; Ruud A Bank; Joseph Mizrahi; Casper G Schalkwijk; Suzanne R Thorpe; John W Baynes; J W J Bijlsma; Floris P J G Lafeber; Johan teKoppele
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
Arthritis and rheumatism 2002;46(1):114-23.
2001: Jeroen DeGroot; Nicole Verzijl; Kim M G Jacobs; M Budde; Ruud A Bank; J W J Bijlsma; Johan teKoppele; Floris P J G Lafeber
Accumulation of advanced glycation endproducts reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(8):720-6.
2001: Xiaodu Wang; R A Bank; Johan teKoppele; C Mauli Agrawal
The role of collagen in determining bone mechanical properties.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2001;19(6):1021-6.
2001: Jeroen DeGroot; Nicole Verzijl; Marion J G Wenting-van Wijk; Ruud A Bank; Floris P J G Lafeber; J W J Bijlsma; Johan teKoppele
Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: the role of advanced glycation end products.
Arthritis and rheumatism 2001;44(11):2562-71.
2001: Arco Verhoeven; Maarten Boers; Johan teKoppele; W H van der Laan; Harry M Markusse; Piet Geusens; Sjef van der Linden
Bone turnover, joint damage and bone mineral density in early rheumatoid arthritis treated with combination therapy including high-dose prednisolone.
Rheumatology (Oxford, England) 2001;40(11):1231-7.
2001: Nicole Verzijl; Jeroen DeGroot; Ruud A Bank; MT Bayliss; J W J Bijlsma; Floris P J G Lafeber; Alice Maroudas; Johan teKoppele
Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover.
Matrix biology : journal of the International Society for Matrix Biology 2001;20(7):409-17.
2001: Willemijn H van der Laan; E Molenaar; Karel H Ronday; J Verheijen; Ferdinand C Breedveld; Robert Greenwald; B A C Dijkmans; Johan teKoppele
Lack of effect of doxycycline on disease activity and joint damage in patients with rheumatoid arthritis. A double blind, placebo controlled trial.
The Journal of rheumatology 2001;28(9):1967-74.
2001: P A J Brama; Ruud A Bank; Johan teKoppele; P René Van Weeren
Training affects the collagen framework of subchondral bone in foals.
Veterinary journal (London, England : 1997) 2001;162(1):24-32.
2001: Jeroen DeGroot; Nicole Verzijl; M Budde; J W J Bijlsma; Floris P J G Lafeber; Johan teKoppele
Accumulation of advanced glycation end products decreases collagen turnover by bovine chondrocytes.
Experimental cell research 2001;266(2):303-10.
2001: Herbert P M Brok; Johan teKoppele; J Hakimi; JA Kerwin; E M Nijenhuis; C W De Groot; R E Bontrop; B A 't Hart
Prophylactic and therapeutic effects of a humanized monoclonal antibody against the IL-2 receptor (DACLIZUMAB) on collagen-induced arthritis (CIA) in rhesus monkeys.
Clinical and experimental immunology 2001;124(1):134-41.
2001: Arco Verhoeven; Maarten Boers; Johan teKoppele; W H van der Laan; JA de Roos; Sjef van der Linden
Reliability of spot samples for assessment of urinary excretion of pyridinoline in patients with rheumatoid arthritis.
Clinical and experimental rheumatology 2001;19(1):78-80.
2001: H Karel Ronday; Willemijn H van der Laan; P P Tak; JA de Roos; Ruud A Bank; Johan teKoppele; C J Froelich; C E Hack; Pancras Hogendoorn; Ferdinand C Breedveld; Jan H Verheijen
Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis.
Rheumatology (Oxford, England) 2001;40(1):55-61.
2000: Nicole Verzijl; Jeroen DeGroot; Suzanne R Thorpe; Ruud A Bank; J Nikki Shaw; Timothy J Lyons; J W J Bijlsma; Floris P J G Lafeber; John W Baynes; Johan teKoppele
Effect of collagen turnover on the accumulation of advanced glycation end products.
The Journal of biological chemistry 2000;275(50):39027-31.
2000: P A J Brama; Johan teKoppele; Ruud A Bank; Ab Barneveld; E C Firth; P René Van Weeren
The influence of strenuous exercise on collagen characteristics of articular cartilage in Thoroughbreds age 2 years.
Equine veterinary journal 2000;32(6):551-4.
2000: Ruud A Bank; Michael Soudry; Alice Maroudas; Joseph Mizrahi; Johan teKoppele
The increased swelling and instantaneous deformation of osteoarthritic cartilage is highly correlated with collagen degradation.
Arthritis and rheumatism 2000;43(10):2202-10.
2000: Maurice H M Wassen; J Lammens; Johan teKoppele; Ralph J B Sakkers; Z Liu; Abraham J Verbout; Ruud A Bank
Collagen structure regulates fibril mineralization in osteogenesis as revealed by cross-link patterns in calcifying callus.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(9):1776-85.
2000: Ivan G Otterness; Marcia L Bliven; James D Eskra; Johan teKoppele; Hans A Stukenbrok; Anthony J Milici
Cartilage damage after intraarticular exposure to collagenase 3.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2000;8(5):366-73.
2000: Nicole Verzijl; Jeroen DeGroot; E Oldehinkel; Ruud A Bank; Suzanne R Thorpe; John W Baynes; MT Bayliss; J W J Bijlsma; Floris P J G Lafeber; Johan teKoppele
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
The Biochemical journal 2000;350 Pt 2():381-7.
2000: Willemijn H van der Laan; Thomas Pap; H Karel Ronday; Jos M Grimbergen; L G M Huisman; Johan teKoppele; Ferdinand C Breedveld; Renate E Gay; Steffen Gay; Tom W J Huizinga; Jan H Verheijen; Paul H A Quax
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor.
Arthritis and rheumatism 2000;43(8):1710-8.
2000: Goris Roosendaal; Johan teKoppele; Marieke E Vianen; H Marijke van den Berg; Floris P J G Lafeber; J W J Bijlsma
Articular cartilage is more susceptible to blood induced damage at young than at old age.
The Journal of rheumatology 2000;27(7):1740-4.
2000: Ruud A Bank; Johan teKoppele; G J M Janus; Maurice H M Wassen; Hans E H Pruijs; H A Van der Sluijs; Ralph J B Sakkers
Pyridinium cross-links in bone of patients with osteogenesis imperfecta: evidence of a normal intrafibrillar collagen packing.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(7):1330-6.
2000: P A J Brama; Johan teKoppele; Ruud A Bank; Ab Barneveld; P René Van Weeren
Functional adaptation of equine articular cartilage: the formation of regional biochemical characteristics up to age one year.
Equine veterinary journal 2000;32(3):217-21.
2000: X Wang; R A Bank; Johan teKoppele; G B Hubbard; Kyriacos A Athanasiou; C Mauli Agrawal
Effect of collagen denaturation on the toughness of bone.
Clinical orthopaedics and related research 2000;(371):228-39.
2000: P A J Brama; Johan teKoppele; B Beekman; Benno van El; Ab Barneveld; P René Van Weeren
Influence of development and joint pathology on stromelysin enzyme activity in equine synovial fluid.
Annals of the rheumatic diseases 2000;59(2):155-7.
2000: P A J Brama; Johan teKoppele; Ruud A Bank; Derek Karssenberg; Ab Barneveld; P René Van Weeren
Topographical mapping of biochemical properties of articular cartilage in the equine fetlock joint.
Equine veterinary journal 2000;32(1):19-26.
1999: P A J Brama; Johan teKoppele; Ruud A Bank; P René Van Weeren; Ab Barneveld
Influence of different exercise levels and age on the biochemical characteristics of immature equine articular cartilage.
Equine veterinary journal. Supplement 1999;(31):55-61.
1999: Christopher Chen; Nancy I Burton-Wurster; George Lust; R A Bank; Johan teKoppele
Compositional and metabolic changes in damaged cartilage are peak-stress, stress-rate, and loading-duration dependent.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1999;17(6):870-9.
1999: B Beekman; J W Drijfhout; H Karel Ronday; Johan teKoppele
Fluorogenic MMP activity assay for plasma including MMPs complexed to alpha 2-macroglobulin.
Annals of the New York Academy of Sciences 1999;878():150-8.
1999: Adrianus M C H van den Nieuwendijk; J C Benningshof; V Wegmann; Ruud A Bank; Johan teKoppele; Johannes Brussee; Arne van der Gen
Synthesis of reduced collagen crosslinks.
Bioorganic & medicinal chemistry letters 1999;9(12):1673-6.
1999: Goris Roosendaal; Johan teKoppele; Marieke E Vianen; H Marijke van den Berg; Floris P J G Lafeber; J W J Bijlsma
Blood-induced joint damage: a canine in vivo study.
Arthritis and rheumatism 1999;42(5):1033-9.
1999: Jeroen DeGroot; Nicole Verzijl; Ruud A Bank; Floris P J G Lafeber; J W Bijlsma; Johan teKoppele
Age-related decrease in proteoglycan synthesis of human articular chondrocytes: the role of nonenzymatic glycation.
Arthritis and rheumatism 1999;42(5):1003-9.
1999: P A J Brama; Johan teKoppele; Ruud A Bank; P René Van Weeren; Ab Barneveld
Influence of site and age on biochemical characteristics of the collagen network of equine articular cartilage.
American journal of veterinary research 1999;60(3):341-5.
1999: James T Handa; N Verzijl; H Matsunaga; AE Aotaki-Keen; Gerard A Lutty; Johan teKoppele; T Miyata; Leonard M Hjelmeland
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.
Investigative ophthalmology & visual science 1999;40(3):775-9.
1999: Ruud A Bank; S P Robins; Cisca Wijmenga; L J Breslau-Siderius; Alfons F J Bardoel; H A van der Sluijs; Hans E H Pruijs; Johan teKoppele
Defective collagen crosslinking in bone, but not in ligament or cartilage, in Bruck syndrome: indications for a bone-specific telopeptide lysyl hydroxylase on chromosome 17.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(3):1054-8.
1999: Ruud A Bank; Johan teKoppele; G Oostingh; Brian L Hazleman; Graham P Riley
Lysylhydroxylation and non-reducible crosslinking of human supraspinatus tendon collagen: changes with age and in chronic rotator cuff tendinitis.
Annals of the rheumatic diseases 1999;58(1):35-41.
1998: Casper G Schalkwijk; Mario Vermeer; Coen D A Stehouwer; Johan teKoppele; H M Princen; Victor W M van Hinsbergh
Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein.
Biochimica et biophysica acta 1998;1394(2-3):187-98.
1998: Johan teKoppele; B Beekman; Nicole Verzijl; J L Koopman; Jeroen DeGroot; Ruud A Bank
Doxycycline inhibits collagen synthesis by differentiated articular chondrocytes.
Advances in dental research 1998;12(2):63-7.
1998: P A J Brama; Johan teKoppele; B Beekman; P René Van Weeren; Ab Barneveld
Matrix metalloproteinase activity in equine synovial fluid: influence of age, osteoarthritis, and osteochondrosis.
Annals of the rheumatic diseases 1998;57(11):697-9.
1998: B Beekman; Nicole Verzijl; JA de Roos; Johan teKoppele
Matrix degradation by chondrocytes cultured in alginate: IL-1 beta induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1998;6(5):330-40.
1998: J G Bessems; Marcel J de Groot; E J Baede; Johan teKoppele; Nico P E Vermeulen
Hydrogen atom abstraction of 3,5-disubstituted analogues of paracetamol by horseradish peroxidase and cytochrome P450.
Xenobiotica; the fate of foreign compounds in biological systems 1998;28(9):855-75.
1998: GA Kleter; J J M Damen; J J Kettenes-van den Bosch; Ruud A Bank; Johan teKoppele; JR Veraart; jacob ten cate
A novel pyrroleninone cross-link from bovine dentine.
Biochimica et biophysica acta 1998;1381(2):179-90.
1998: RA Smulders; Coen D A Stehouwer; Casper G Schalkwijk; A J M Donker; Victor W M van Hinsbergh; Johan teKoppele
Distinct associations of HbA1c and the urinary excretion of pentosidine, an advanced glycosylation end-product, with markers of endothelial function in insulin-dependent diabetes mellitus.
Thrombosis and haemostasis 1998;80(1):52-7.
1998: JR Veraart; S J Kok; Johan teKoppele; Cees Gooijer; Henk Lingeman; Nel H Velthorst; Udo A Th Brinkman
Capillary electrophoresis of the collagen crosslinks HP and LP utilizing absorbance, wavelength-resolved laser-induced fluorescence and conventional fluorescence detection.
Biomedical chromatography : BMC 1998;12(4):226-31.
1998: BA Hart; Ruud A Bank; JA de Roos; Herbert P M Brok; margreet jonker; H M Theuns; J Hakimi; Johan teKoppele
Collagen-induced arthritis in rhesus monkeys: evaluation of markers for inflammation and joint degradation.
British journal of rheumatology 1998;37(3):314-23.
1998: Ruud A Bank; MT Bayliss; Floris P J G Lafeber; Alice Maroudas; Johan teKoppele
Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage.
The Biochemical journal 1998;330 ( Pt 1)():345-51.
1998: H Karel Ronday; Johan teKoppele; Robert Greenwald; SA Moak; JA de Roos; B A Dijkmans; Ferdinand C Breedveld; Jan H Verheijen
Tranexamic acid, an inhibitor of plasminogen activation, reduces urinary collagen cross-link excretion in both experimental and rheumatoid arthritis.
British journal of rheumatology 1998;37(1):34-8.
1997: Ruud A Bank; B Beekman; R Tenni; Johan teKoppele
Pre-column derivatisation method for the measurement of glycosylated hydroxylysines of collagenous proteins.
Journal of chromatography. B, Biomedical sciences and applications 1997;703(1-2):267-72.
1997: Ruud A Bank; B Beekman; Nicole Verzijl; JA de Roos; A N Sakkee; Johan teKoppele
Sensitive fluorimetric quantitation of pyridinium and pentosidine crosslinks in biological samples in a single high-performance liquid chromatographic run.
Journal of chromatography. B, Biomedical sciences and applications 1997;703(1-2):37-44.
1997: B Beekman; Benno van El; J W Drijfhout; H Karel Ronday; Johan teKoppele
Highly increased levels of active stromelysin in rheumatoid synovial fluid determined by a selective fluorogenic assay.
FEBS letters 1997;418(3):305-9.
1997: B Beekman; Nicole Verzijl; Ruud A Bank; Klaus von der Mark; Johan teKoppele
Synthesis of collagen by bovine chondrocytes cultured in alginate; posttranslational modifications and cell-matrix interaction.
Experimental cell research 1997;237(1):135-41.
1997: Ruud A Bank; M Krikken; B Beekman; reinout stoop; Alice Maroudas; Floris P J G Lafeber; Johan teKoppele
A simplified measurement of degraded collagen in tissues: application in healthy, fibrillated and osteoarthritic cartilage.
Matrix biology : journal of the International Society for Matrix Biology 1997;16(5):233-43.
1997: JIMMY MOLYNEUX; C Bijkerk; S C de Wildt; H S Miedema; HA Valkenburg; F C Breedveld; Huibert A P Pols; Johan teKoppele; V F Sloos; Albert Hofman; P Eline Slagboom; C.M. Duijn
Investigation of the association of the CRTM and CRTL1 genes with radiographically evident osteoarthritis in subjects from the Rotterdam study.
Arthritis and rheumatism 1997;40(10):1760-5.
1997: B Beekman; Nicole Verzijl; JA de Roos; J L Koopman; Johan teKoppele
Doxyclycline inhibits collagen synthesis by bovine chondrocytes cultured in alginate.
Biochemical and biophysical research communications 1997;237(1):107-10.
1997: AA van Valburg; M J G Wenting; B Beekman; Johan teKoppele; Floris P J G Lafeber; J W J Bijlsma
Degenerated human articular cartilage at autopsy represents preclinical osteoarthritic cartilage: comparison with clinically defined osteoarthritic cartilage.
The Journal of rheumatology 1997;24(2):358-64.
1996: Johan teKoppele; Paul J Lucassen; A N Sakkee; J G Van Asten; Rivka Ravid; Dick F Swaab; C F Van Bezooijen
8OHdG levels in brain do not indicate oxidative DNA damage in Alzheimer's disease.
Neurobiology of aging 1996;17(6):819-26.
1996: Ruud A Bank; E J Jansen; B Beekman; Johan teKoppele
Amino acid analysis by reverse-phase high-performance liquid chromatography: improved derivatization and detection conditions with 9-fluorenylmethyl chloroformate.
Analytical biochemistry 1996;240(2):167-76.
1996: B Beekman; Jan Wouter Drijfhout; W Bloemhoff; H Karel Ronday; P P Tak; Johan teKoppele
Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological media.
FEBS letters 1996;390(2):221-5.
1996: J G Bessems; Johan teKoppele; P A Van Dijk; L L Van Stee; Jan N M Commandeur; Nico P E Vermeulen
Rat liver microsomal cytochrome P450-dependent oxidation of 3,5-disubstituted analogues of paracetamol.
Xenobiotica; the fate of foreign compounds in biological systems 1996;26(6):647-66.
1996: JIMMY MOLYNEUX; Charlene Williams; Johan teKoppele; G C Van de Giessen; P Eline Slagboom
Population haplotype analysis and evolutionary relations of the COL2A1 gene.
Annals of human genetics 1996;60(Pt 3):189-99.
1996: E M van der Aar; D Buikema; Jan N M Commandeur; Johan teKoppele; Ben van Ommen; Peter J van Bladeren; Nico P E Vermeulen
Enzyme kinetics and substrate selectivities of rat glutathione S-transferase isoenzymes towards a series of new 2-substituted 1-chloro-4-nitrobenzenes.
Xenobiotica; the fate of foreign compounds in biological systems 1996;26(2):143-55.
1995: J G Bessems; H D Gaisser; Johan teKoppele; W P Van Bennekom; Jan N M Commandeur; Nico P E Vermeulen
3,5-Disubstituted analogues of paracetamol. Synthesis, analgesic activity and cytotoxicity.
Chemico-biological interactions 1995;98(3):237-50.
1995: J G Van Asten; Johan teKoppele; G J Horbach
The influence of aging on dimethylnitrosamine-demethylase enzyme kinetics in rat liver microsomes.
Mechanisms of ageing and development 1995;82(2-3):63-72.
1995: A R Goeptar; Johan teKoppele; H R Glatt; Ed J Groot; Albrecht Seidel; M Barrenscheen; C Wölfel; Johannes Doehmer; Nico P E Vermeulen
The cytotoxicity of mitomycin C and adriamycin in genetically engineered V79 cell lines and freshly isolated rat hepatocytes.
Chemico-biological interactions 1995;97(2):149-68.
1995: M Maliepaard; Nico J de Mol; LH Janssen; A R Goeptar; Johan teKoppele; Nico P E Vermeulen; W Verboom; D N Reinhoudt
Reduction of antitumour mitosenes in non-aqueous and aqueous environment. An electron spin resonance and cyclic voltammetry study.
Free radical research 1995;22(2):109-21.
1993: A R Goeptar; Johan teKoppele; E K Lamme; J M Piqué; Nico P E Vermeulen
Cytochrome P450 2B1-mediated one-electron reduction of adriamycin: a study with rat liver microsomes and purified enzymes.
Molecular pharmacology 1993;44(6):1267-77.
1993: L Koymans; G M Donné-Op den Kelder; Johan teKoppele; Nico P E Vermeulen
Generalized cytochrome P450-mediated oxidation and oxygenation reactions in aromatic substrates with activated N-H, O-H, C-H, or S-H substituents.
Xenobiotica; the fate of foreign compounds in biological systems 1993;23(6):633-48.
1993: G J Stijntjes; Jan N M Commandeur; Johan teKoppele; S McGuinness; A Gandolfi; Nico P E Vermeulen
Examination of the structure-toxicity relationships of L-cysteine-S-conjugates of halogenated alkenes and their corresponding mercapturic acids in rat renal tissue slices.
Toxicology 1993;79(1):67-79.
1992: G J Stijntjes; Johan teKoppele; Nico P E Vermeulen
High-performance liquid chromatography-fluorescence assay of pyruvic acid to determine cysteine conjugate beta-lyase activity: application to S-1,2-dichlorovinyl-L-cysteine and S-2-benzothiazolyl-L-cysteine.
Analytical biochemistry 1992;206(2):334-43.
1992: A R Goeptar; Johan teKoppele; E P Neve; Nico P E Vermeulen
Reductase and oxidase activity of rat liver cytochrome P450 with 2,3,5,6-tetramethylbenzoquinone as substrate.
Chemico-biological interactions 1992;83(3):249-69.
1992: L Koymans; Nico P E Vermeulen; Saskia van Acker; Johan teKoppele; J J Heykants; Karel Lavrijsen; W Meuldermans; G M Donné-Op den Kelder
A predictive model for substrates of cytochrome P450-debrisoquine (2D6).
Chemical research in toxicology 1992;5(2):211-9.
1992: A R Goeptar; Johan teKoppele; J M van Maanen; C E Zoetemelk; Nico P E Vermeulen
One-electron reductive bioactivation of 2,3,5,6-tetramethylbenzoquinone by cytochrome P450.
Biochemical pharmacology 1992;43(2):343-52.
1991: Johan teKoppele; B J Keller; J C Caldwell-Kenkel; John J Lemasters; Ronald G Thurman
Effect of hepatotoxic chemicals and hypoxia on hepatic nonparenchymal cells: impairment of phagocytosis by Kupffer cells and disruption of the endothelium in rat livers perfused with colloidal carbon.
Toxicology and applied pharmacology 1991;110(1):20-30.
1991: K L Wall; W S Gao; Johan teKoppele; G Y Kwei; F C Kauffman; Ronald G Thurman
The liver plays a central role in the mechanism of chemical carcinogenesis due to polycyclic aromatic hydrocarbons.
Carcinogenesis 1991;12(5):783-6.
1991: Johan teKoppele; G J Mulder
Stereoselective glutathione conjugation by subcellular fractions and purified glutathione S-transferases.
Drug metabolism reviews 1991;23(3-4):331-54.
1991: Gerard J Mulder; Johan teKoppele; C G Schipper; W H Snel; K Sandy Pang; M Polhuijs
Stereoselectivity of glutathione conjugation in vivo, in the perfused liver and in isolated hepatocytes.
Drug metabolism reviews 1991;23(3-4):311-30.
1990: Johan teKoppele; Ronald G Thurman
Phagocytosis by Kupffer cells predominates in pericentral regions of the liver lobule.
The American journal of physiology 1990;259(5 Pt 1):G814-21.
1989: M Polhuijs; Johan teKoppele; E Fockens; Gerard J Mulder
Glutathione conjugation of the alpha-bromoisovaleric acid enantiomers in the rat in vivo and its stereoselectivity. Pharmacokinetics of biliary and urinary excretion of the glutathione conjugate and the mercapturate.
Biochemical pharmacology 1989;38(22):3957-62.
1989: Johan teKoppele; C Schipper; Douwe D Breimer; Gerard J Mulder
Stereoselectivity in the urinary excretion of the mercapturates of (R-) and (S-) alpha-bromoisovalerylurea in man.
British journal of clinical pharmacology 1989;28(2):151-4.
1989: I Anundi; F C Kauffman; Johan teKoppele; H Yamanaka; M Whittaker; J A Popp; Ronald G Thurman
Adenine nucleotides and carbohydrates in subpopulations of hepatic nodules with normal and compromised microcirculation.
Cancer research 1989;49(12):3282-6.
1988: Johan teKoppele; B Coles; B Ketterer; Gerard J Mulder
Stereoselectivity of rat liver glutathione transferase isoenzymes for alpha-bromoisovaleric acid and alpha-bromoisovalerylurea enantiomers.
The Biochemical journal 1988;252(1):137-42.
1988: Johan teKoppele; E J van der Mark; Gerard J Mulder
Liquid chromatographic determination of diastereomeric glutathione conjugates and further derivatives of alpha-bromoisovalerylurea in rat bile and urine by electrochemically generated bromine.
Journal of chromatography 1988;427(1):67-77.
1988: Johan teKoppele; S W Esajas; Johannes Brussee; A van der Gen; Gerard J Mulder
Stereoselective glutathione conjugation of the separate alpha-bromoisovalerylurea and alpha-bromoisovaleric acid enantiomers in the rat in vivo and in rat liver subcellular fractions.
Biochemical pharmacology 1988;37(1):29-35.
1987: Johan teKoppele; I A de Lannoy; K Sandy Pang; Gerard J Mulder
Stereoselective glutathione conjugation and amidase-catalyzed hydrolysis of alpha-bromoisovalerylurea enantiomers in isolated rat hepatocytes.
The Journal of pharmacology and experimental therapeutics 1987;243(1):349-55.
1987: P R Kerklaan; S Bouter; Johan teKoppele; N P Vermeulen; P J van Bladeren; G R Mohn
Mutagenicity of halogenated and other substituted dinitrobenzenes in Salmonella typhimurium TA100 and derivatives deficient in glutathione (TA100/GSH-) and nitroreductase (TA100NR).
Mutation research 1987;176(2):171-8.
1986: Johan teKoppele; P Dogterom; N P Vermeulen; D K Meijer; A van der Gen; Gerard J Mulder
alpha-Bromoisovalerylurea as model substrate for studies on pharmacokinetics of glutathione conjugation in the rat. II. Pharmacokinetics and stereoselectivity of metabolism and excretion in vivo and in the perfused liver.
The Journal of pharmacology and experimental therapeutics 1986;239(3):905-14.
1986: Johan teKoppele; E J van der Mark; J C Olde Boerrigter; Johannes Brussee; A van der Gen; J van der Greef; Gerard J Mulder
alpha-Bromoisovalerylurea as model substrate for studies on pharmacokinetics of glutathione conjugation in the rat. I. (Bio-) synthesis, analysis and identification of diastereomeric glutathione conjugates and mercapturates.
The Journal of pharmacology and experimental therapeutics 1986;239(3):898-904.
1986: K Sandy Pang; V Yuen; S Fayz; Johan teKoppele; Gerard J Mulder
Absorption and metabolism of acetaminophen by the in situ perfused rat small intestine preparation.
Drug metabolism and disposition: the biological fate of chemicals 1986;14(1):102-11.