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Doriana Fruci

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Chemicals & Drugs

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Amino Acid Sequences

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Publications

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Doriana Fruci; Maria Benevolo; Loredana Cifaldi; Elisa Lo Monaco; Franco Locatelli; Elisa Tremante; Patrizio Giacomini
T and NK cells: two sides of tumor immunoevasion.
Alessandra Fierabracci; Franco Locatelli; Annamaria Milillo; Doriana Fruci
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: insights from genomic-wide association studies.
Simonetta Pazzaglia; Anna Saran; Loredana Cifaldi; Doriana Fruci; Valerio Nobili; Anna Alisi
Hedgehog/hyaluronic acid interaction network in nonalcoholic fatty liver disease, fibrosis, and hepatocellular carcinoma.

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All Publications

2013: Doriana Fruci; Maria Benevolo; Loredana Cifaldi; Elisa Lo Monaco; Franco Locatelli; Elisa Tremante; Patrizio Giacomini
T and NK cells: two sides of tumor immunoevasion.
Journal of translational medicine 2013;11():30.
2012: Alessandra Fierabracci; Franco Locatelli; Annamaria Milillo; Doriana Fruci
The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: insights from genomic-wide association studies.
Autoimmunity reviews 2012;12(2):281-8.
2012: Simonetta Pazzaglia; Anna Saran; Loredana Cifaldi; Doriana Fruci; Valerio Nobili; Anna Alisi
Hedgehog/hyaluronic acid interaction network in nonalcoholic fatty liver disease, fibrosis, and hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2012;56(4):1589.
2012: Arianna Citti; Luigi De Sio; Anna Alisi; Renata Boldrini; Alessandro Inserra; Franco Locatelli; Angela Mastronuzzi; Rosanna Pessolano; Angelo Rosolen; Angelica Zin; Doriana Fruci
Expression of multidrug resistance-associated proteins in paediatric soft tissue sarcomas before and after chemotherapy.
International journal of oncology 2012;41(1):117-24.
2012: Doriana Fruci; Maria Benevolo; L Cifaldi; E Lo Monaco; S Lorenzi; E Tremante; P Giacomini
Major histocompatibility complex class i and tumour immuno-evasion: how to fool T cells and natural killer cells at one time.
Current oncology (Toronto, Ont.) 2012;19(1):39-41.
2012: Paolo Romania; Alice Bertaina; Giorgia Bracaglia; Doriana Fruci; Franco Locatelli; Rossella Rota
Epigenetic Deregulation of MicroRNAs in Rhabdomyosarcoma and Neuroblastoma and Translational Perspectives.
International journal of molecular sciences 2012;13(12):16554-79.
2012: Silvia Lorenzi; Marco Pezzullo; Vincenzo Russo; Pierre van der Bruggen; Chiara Antonucci; Renata Boldrini; Aurora Castellano; Loredana Cifaldi; Arianna Citti; Matteo Forloni; Patrizio Giacomini; Franco Locatelli; Doriana Fruci
IRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastoma.
PloS one 2012;7(10):e46928.
2012: Loredana Cifaldi; Franco Locatelli; Silvia Lorenzi; Paolo Romania; Doriana Fruci
Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.
International journal of molecular sciences 2012;13(7):8338-52.
2011: Loredana Cifaldi; Elisa Lo Monaco; Matteo Forloni; Ezio Giorda; Silvia Lorenzi; Stefania Petrini; Elisa Tremante; Daniela Pende; Franco Locatelli; Patrizio Giacomini; Doriana Fruci
Natural killer cells efficiently reject lymphoma silenced for the endoplasmic reticulum aminopeptidase associated with antigen processing.
Cancer research 2011;71(5):1597-606.
2010: Elisa Lo Monaco; Elisa Tremante; Loredana Cifaldi; Doriana Fruci; Patrizio Giacomini
HLA-E and the origin of immunogenic self HLA epitopes.
Molecular immunology 2010;47(9):1661-2; author reply 1163-4.
2010: Matteo Forloni; Sonia Albini; Maria Zaira Limongi; Loredana Cifaldi; Renata Boldrini; Maria Rita Nicotra; Giuseppe Giannini; Pier Giorgio Natali; Patrizio Giacomini; Doriana Fruci
NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells.
Cancer research 2010;70(3):916-24.
2009: Anna Taranta; Alessandra Gianviti; Alessia Palma; Veronica De Luca; Liliana Mannucci; Maria Antonietta Procaccino; Gian Marco Ghiggeri; Gianluca Caridi; Doriana Fruci; Silvia Ferracuti; Alfonso Ferretti; Carmine Pecoraro; Maurizio Gaido; Rosa Penza; Alberto Edefonti; Luisa Murer; Alberto Tozzi; francesco emma
Genetic risk factors in typical haemolytic uraemic syndrome.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(6):1851-7.
2009: Aline Martayan; Leonardo Sibilio; Elisa Tremante; Elisa Lo Monaco; Arend Mulder; Doriana Fruci; Agata Cova; Licia Rivoltini; Patrizio Giacomini
Class I HLA folding and antigen presentation in beta 2-microglobulin-defective Daudi cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3609-17.
2008: Doriana Fruci; Patrizio Giacomini; Maria Rita Nicotra; Matteo Forloni; Rocco Fraioli; Loredana Saveanu; Peter van Endert; Pier Giorgio Natali
Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues.
Journal of cellular physiology 2008;216(3):742-9.
2008: Aline Martayan; Leonardo Sibilio; Andrea Setini; Elisa Lo Monaco; Elisa Tremante; Doriana Fruci; Marco COLONna; Patrizio Giacomini
N-linked glycosylation selectively regulates the generic folding of HLA-Cw1.
The Journal of biological chemistry 2008;283(24):16469-76.
2008: Laura Fontana; Micol E Fiori; Sonia Albini; Loredana Cifaldi; Serena Giovinazzi; Matteo Forloni; Renata Boldrini; Alberto Donfrancesco; Valentina Federici; Patrizio Giacomini; Cesare Peschle; Doriana Fruci
Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM.
PloS one 2008;3(5):e2236.
2006: Alberto Chersi; Silvia Ferracuti; Giuliana Falasca; Richard H Butler; Doriana Fruci
Assembly and selective "in synthesis" labeling of quenched fluorogenic protease substrates.
Analytical biochemistry 2006;357(2):194-9.
2006: Doriana Fruci; Silvia Ferracuti; Maria Zaira Limongi; Veronica Cunsolo; Ezio Giorda; Rocco Fraioli; Leonardo Sibilio; Oliver Carroll; Akira Hattori; Peter van Endert; Patrizio Giacomini
Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4869-79.
2006: Annalisa Botta; caldarola sara; Laura Vallo; Emanuela Bonifazi; Doriana Fruci; Francesca Gullotta; Roberto Massa; Giuseppe Novelli; Fabrizio Loreni
Effect of the [CCTG]n repeat expansion on ZNF9 expression in myotonic dystrophy type II (DM2).
Biochimica et biophysica acta 2006;1762(3):329-34.
2005: Leonardo Sibilio; Aline Martayan; Andrea Setini; Rocco Fraioli; Doriana Fruci; Jeffrey Shabanowitz; Donald F Hunt; Patrizio Giacomini
Impaired assembly results in the accumulation of multiple HLA-C heavy chain folding intermediates.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6651-8.
2005: Paolo Catarsi; Roberto Ravazzolo; francesco emma; Doriana Fruci; Livio Finos; Andrea Frau; Giacomo Morreale; Alba Carrea; Gian Marco Ghiggeri
Angiotensin-converting enzyme (ACE) haplotypes and cyclosporine A (CsA) response: a model of the complex relationship between ACE quantitative trait locus and pathological phenotypes.
Human molecular genetics 2005;14(16):2357-67.
2005: Loredana Saveanu; Oliver Carroll; Vivian Lindo; Margarita Del-Val; DANIEL LOPEZ; yves lepelletier; Fiona Greer; Lutz Schomburg; Doriana Fruci; Gabriele Niedermann; Peter van Endert
Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.
Nature immunology 2005;6(7):689-97.
2004: Gian Franco Bottazzo; M Locatelli; Alessandra Fierabracci; Doriana Fruci
The genetic basis of immune and autoimmune responses.
Acta paediatrica (Oslo, Norway : 1992). Supplement 2004;93(445):38-42.
2004: Beatriz C Gil-Torregrosa; Ana-Maria Lennon-Duménil; Benedikt Kessler; Pierre Guermonprez; Hidde L Ploegh; Doriana Fruci; Peter van Endert; Sebastian Amigorena
Control of cross-presentation during dendritic cell maturation.
European journal of immunology 2004;34(2):398-407.
2003: Doriana Fruci; Gregoire Lauvau; Loredana Saveanu; Massimo Amicosante; Richard H Butler; Axel Polack; Ginhoux Florent; François Lemonnier; Hueseyin Firat; Peter van Endert
Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(6):2977-84.
2002: Loredana Saveanu; Doriana Fruci; Peter van Endert
Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases.
Molecular immunology 2002;39(3-4):203-15.
2001: Doriana Fruci; Gabriele Niedermann; Richard H Butler; Peter van Endert
Efficient MHC class I-independent amino-terminal trimming of epitope precursor peptides in the endoplasmic reticulum.
Immunity 2001;15(3):467-76.
1999: Sandra D'Alfonso; Lorenza Nisticò; Patrizia Zavattari; Maria Giovanna Marrosu; Raffaele Murru; Marina Lai; Luca Massacesi; Clara Ballerini; D Gestri; Marco Salvetti; Giovanni Ristori; Roberto Bomprezzi; Maria Trojano; Maria Liguori; Domenico Gambi; A Quattrone; Doriana Fruci; Francesco Cucca; PM Richiardi; Roberto Tosi
Linkage analysis of multiple sclerosis with candidate region markers in Sardinian and Continental Italian families.
European journal of human genetics : EJHG 1999;7(3):377-85.
1996: Katharina Fleischhauer; Doriana Fruci; Peter van Endert; J Herman; Silvia Tanzarella; H J Wallny; Pierre G Coulie; Claudio Bordignon; Catia Traversari
Characterization of antigenic peptides presented by HLA-B44 molecules on tumor cells expressing the gene MAGE-3.
International journal of cancer. Journal international du cancer 1996;68(5):622-8.
1996: G Greco; Doriana Fruci; Daniele Accapezzato; Vincenzo Barnaba; R Nisini; G Alimena; E Montefusco; E Vigneti; R Butler; N Tanigaki; Roberto Tosi
Two brc-abl junction peptides bind HLA-A3 molecules and allow specific induction of human cytotoxic T lymphocytes.
Leukemia 1996;10(4):693-9.
1995: Paolo Rovero; S Viganò; Stefano Pegoraro; Roberto P Revoltella; D Riganelli; Doriana Fruci; G Greco; R H Butler; N Tanigaki
Augmentation of the affinity of HLA class I-binding peptides lacking primary anchor residues by manipulation of the secondary anchor residues.
Journal of peptide science : an official publication of the European Peptide Society 1995;1(4):266-73.
1995: Doriana Fruci; R H Butler; G Greco; Paolo Rovero; L Pazmany; E Vigneti; Roberto Tosi; N Tanigaki
Differences in peptide-binding specificity of two ankylosing spondylitis-associated HLA-B27 subtypes.
Immunogenetics 1995;42(2):123-8.
1994: Doriana Fruci; G Greco; E Vigneti; N Tanigaki; R H Butler; Roberto Tosi
The peptide-binding specificity of HLA-B27 subtype (B*2705) analyzed by the use of polyalanine model peptides.
Human immunology 1994;41(1):34-8.
1994: N Tanigaki; Doriana Fruci; N Groome; R H Butler; M Londei; Roberto Tosi
Exploring myelin basic protein for HLA class I-binding sequences.
European journal of immunology 1994;24(9):2196-202.
1994: Paolo Rovero; D Riganelli; Doriana Fruci; S Viganò; S Pegoŕaro; Roberto P Revoltella; G Greco; R Butler; S Clementi; N Tanigaki
The importance of secondary anchor residue motifs of HLA class I proteins: a chemometric approach.
Molecular immunology 1994;31(7):549-54.
1994: N Tanigaki; Doriana Fruci; Alberto Chersi; Giuliana Falasca; Roberto Tosi; R H Butler
HLA-A2-binding peptides cross-react not only within the A2 subgroup but also with other HLA-A-locus allelic products.
Human immunology 1994;39(3):155-62.
1994: N Tanigaki; Doriana Fruci; E Vigneti; G Starace; Paolo Rovero; M Londei; R H Butler; Roberto Tosi
The peptide binding specificity of HLA-B27 subtypes.
Immunogenetics 1994;40(3):192-8.
1993: Doriana Fruci; Paolo Rovero; Giuliana Falasca; Alberto Chersi; R Sorrentino; R Butler; N Tanigaki; Roberto Tosi
Anchor residue motifs of HLA class-I-binding peptides analyzed by the direct binding of synthetic peptides to HLA class I alpha chains.
Human immunology 1993;38(3):187-92.
1993: N Tanigaki; Doriana Fruci; Alberto Chersi; R H Butler
Unfolded HLA class I alpha chains and their use in an assay of HLA class-I-peptide binding.
Human immunology 1993;36(2):119-27.
1993: Doriana Fruci; Paolo Rovero; R H Butler; R Sorrentino; Roberto Tosi; N Tanigaki
HLA class I binding of synthetic nonamer peptides carrying major anchor residue motifs of HLA-B27 (B*2705)-binding peptides.
Immunogenetics 1993;38(1):41-6.
1991: R H Butler; Patrizia Ghelardini; Doriana Fruci; L Paolozzi
Global changes in gene expression in Escherichia coli K12 induced by bacteriophage Mu Gem protein.
Research in microbiology 1991;142(1):13-21.