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Maria Castedo
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Research Profile (preview)
Chemicals & Drugs
Anatomy
Living Beings
Physiology
Disorders
Concepts & Ideas
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Network (preview)
57
Kroemer, Guido
21
Zamzami, Naoufal
17
Roumier, Thomas
17
PERFETTINI, Jean-Luc
15
MARCHETTI, Philippe
12
Susin, Santos
12
Métivier, Didier
11
Hirsch, T
9
Andreau, Karine
8
Piacentini, Mauro
8
Macho, Antonio
7
Vitale, Ilio
7
Vivet, Sonia
7
Decaudin, Didier
5
Ferri, Karine
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Geonetwork of Maria Castedo (preview)
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All Publications
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2009: Tao Yungan; Leteur Céline; Calderaro Julien; Girdler Fiona; Zhang Ping; Frascogna Valérie; Varna Mariana; Opolon Paule; Castedo Maria; Bourhis Jean; Kroemer Guido; Deutsch Eric
The aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe.
Cell cycle (Georgetown, Tex.) 2009;8(19):3172-81.
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2009: Senovilla Laura; Vitale Ilio; Galluzzi Lorenzo; Vivet Sonia; Joza Nicholas; Younes Amena Ben; Rello-Varona Santiago; Castedo Maria; Kroemer Guido
p53 represses the polyploidization of primary mammary epithelial cells by activating apoptosis.
Cell cycle (Georgetown, Tex.) 2009;8(9):1380-5.
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2009: Tao Yungan; Leteur Céline; Yang Ceyao; Zhang Ping; Castedo Maria; Pierré Alain; Golsteyn Roy M; Bourhis Jean; Kroemer Guido; Deutsch Eric
Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.
Cell cycle (Georgetown, Tex.) 2009;8(8):1196-205.
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2009: Rello-Varona Santiago; Vitale Ilio; Kepp Oliver; Senovilla Laura; Jemaá Mohamed; Métivier Didier; Castedo Maria; Kroemer Guido
Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5.
Cell cycle (Georgetown, Tex.) 2009;8(7):1030-5.
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2007: Zermati Yael; Mouhamad Shahul; Stergiou Lilli; Besse Benjamin; Galluzzi Lorenzo; Boehrer Simone; Pauleau Anne-Laure; Rosselli Filippo; D'Amelio Marcello; Amendola Roberto; Castedo Maria; Hengartner Michael; Soria Jean-Charles; Cecconi Francesco; Kroemer Guido
Nonapoptotic role for Apaf-1 in the DNA damage checkpoint.
Molecular cell 2007;28(4):624-37.
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2007: Galluzzi L; Maiuri M C; Vitale I; Zischka H; Castedo M; Zitvogel L; Kroemer G
Cell death modalities: classification and pathophysiological implications.
Cell death and differentiation 2007;14(7):1237-43.
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2007: Büttner Sabrina; Carmona-Gutierrez Didac; Vitale Ilio; Castedo Maria; Ruli Doris; Eisenberg Tobias; Kroemer Guido; Madeo Frank
Depletion of endonuclease G selectively kills polyploid cells.
Cell cycle (Georgetown, Tex.) 2007;6(9):1072-6.
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2007: Obeid Michel; Tesniere Antoine; Ghiringhelli François; Fimia Gian Maria; Apetoh Lionel; Perfettini Jean-Luc; Castedo Maria; Mignot Grégoire; Panaretakis Theoharis; Casares Noelia; Métivier Didier; Larochette Nathanael; van Endert Peter; Ciccosanti Fabiola; Piacentini Mauro; Zitvogel Laurence; Kroemer Guido
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Nature medicine 2007;13(1):54-61.
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2007: Vitale Ilio; Galluzzi Lorenzo; Vivet Sonia; Nanty Lisa; Dessen Philippe; Senovilla Laura; Olaussen Ken A; Lazar Vladimir; Prudhomme Michelle; Golsteyn Roy M; Castedo Maria; Kroemer Guido
Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway.
PloS one 2007;2(12):e1337.
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2006: Castedo Maria; Coquelle Arnaud; Vitale Ilio; Vivet Sonia; Mouhamad Shahul; Viaud Sophie; Zitvogel Laurence; Kroemer Guido
Selective resistance of tetraploid cancer cells against DNA damage-induced apoptosis.
Annals of the New York Academy of Sciences 2006;1090():35-49.
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2006: Zhang P; Castedo M; Tao Y; Violot D; Métivier D; Deutsch E; Kroemer G; Bourhis Jean
Caspase independence of radio-induced cell death.
Oncogene 2006;25(59):7758-70.
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2006: Coquelle Arnaud; Mouhamad Shahul; Pequignot Marie O; Braun Thorsten; Carvalho Gabrielle; Vivet Sonia; Métivier Didier; Castedo Maria; Kroemer Guido
Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis.
Biochemical pharmacology 2006;72(11):1396-404.
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2006: Castedo Maria; Coquelle Arnaud; Vivet Sonia; Vitale Ilio; Kauffmann Audrey; Dessen Philippe; Pequignot Marie O; Casares Noelia; Valent Alexandre; Mouhamad Shahul; Schmitt Elise; Modjtahedi Nazanine; Vainchenker William; Zitvogel Laurence; Lazar Vladimir; Garrido Carmen; Kroemer Guido
Apoptosis regulation in tetraploid cancer cells.
The EMBO journal 2006;25(11):2584-95.
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2006: Coquelle A; Mouhamad S; Pequignot M O; Braun T; Carvalho G; Vivet S; Métivier D; Castedo M; Kroemer G
Cell cycle-dependent cytotoxic and cytostatic effects of bortezomib on colon carcinoma cells.
Cell death and differentiation 2006;13(5):873-5.
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2006: Roumier T; Szabadkai G; Simoni A-M; Perfettini J-L; Paulau A-L; Castedo M; Métivier D; Badley A; Rizzuto R; Kroemer G
HIV-1 protease inhibitors and cytomegalovirus vMIA induce mitochondrial fragmentation without triggering apoptosis.
Cell death and differentiation 2006;13(2):348-51.
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2005: Perfettini J-L; Castedo M; Roumier T; Andreau K; Nardacci R; Piacentini M; Kroemer G
Mechanisms of apoptosis induction by the HIV-1 envelope.
Cell death and differentiation 2005;12 Suppl 1():916-23.
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2005: Castedo Maria; Perfettini Jean-Luc; Piacentini Mauro; Kroemer Guido
p53-A pro-apoptotic signal transducer involved in AIDS.
Biochemical and biophysical research communications 2005;331(3):701-6.
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2005: Perfettini Jean-Luc; Castedo Maria; Nardacci Roberta; Ciccosanti Fabiola; Boya Patricia; Roumier Thomas; Larochette Nathanael; Piacentini Mauro; Kroemer Guido
Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope.
The Journal of experimental medicine 2005;201(2):279-89.
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2005: Roumier T; Valent A; Perfettini J-L; Métivier D; Castedo M; Kroemer G
A cellular machine generating apoptosis-prone aneuploid cells.
Cell death and differentiation 2005;12(1):91-3.
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2004: Andreau Karine; Castedo Maria; Perfettini Jean-Luc; Roumier Thomas; Pichart Evelyne; Souquere Sylvie; Vivet Sonia; Larochette Nathanael; Kroemer Guido
Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.
The Journal of biological chemistry 2004;279(53):55937-45.
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2004: Andreau Karine; Perfettini Jean-Luc; Castedo Maria; Métivier Didier; Scott Véronique; Pierron Gérard; Kroemer Guido
Contagious apoptosis facilitated by the HIV-1 envelope: fusion-induced cell-to-cell transmission of a lethal signal.
Journal of cell science 2004;117(Pt 23):5643-53.
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2004: Castedo Maria; Perfettini Jean-Luc; Roumier Thomas; Valent Alexander; Raslova Hana; Yakushijin Kenichi; Horne David; Feunteun Jean; Lenoir Gilbert; Medema René; Vainchenker William; Kroemer Guido
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.
Oncogene 2004;23(25):4362-70.
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2004: Castedo Maria; Perfettini Jean-Luc; Roumier Thomas; Yakushijin Kenichi; Horne David; Medema René; Kroemer Guido
The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
Oncogene 2004;23(25):4353-61.
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2004: Castedo Maria; Perfettini Jean-Luc; Roumier Thomas; Andreau Karine; Medema Rene; Kroemer Guido
Cell death by mitotic catastrophe: a molecular definition.
Oncogene 2004;23(16):2825-37.
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2004: Perfettini Jean-Luc; Roumier Thomas; Castedo Maria; Larochette Nathanael; Boya Patricia; Raynal Brigitte; Lazar Vladimir; Ciccosanti Fabiola; Nardacci Roberta; Penninger Josef; Piacentini Mauro; Kroemer Guido
NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope.
The Journal of experimental medicine 2004;199(5):629-40.
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2004: Tintignac Lionel A J; Sirri Valentina; Leibovitch Marie Pierre; Lécluse Yann; Castedo Maria; Metivier Didier; Kroemer Guido; Leibovitch Serge A
Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry.
Molecular and cellular biology 2004;24(4):1809-21.
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2004: Castedo Maria; Kroemer Guido
[Mitotic catastrophe: a special case of apoptosis]
Journal de la Société de biologie 2004;198(2):97-103.
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2003: Castedo Maria; Perfettini Jean-Luc; Andreau Karine; Roumier Thomas; Piacentini Mauro; Kroemer Guido
Mitochondrial apoptosis induced by the HIV-1 envelope.
Annals of the New York Academy of Sciences 2003;1010():19-28.
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2003: Roumier Thomas; Castedo Maria; Perfettini Jean-Luc; Andreau Karine; Métivier Didier; Zamzami Naoufal; Kroemer Guido
Mitochondrion-dependent caspase activation by the HIV-1 envelope.
Biochemical pharmacology 2003;66(8):1321-9.
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2003: Boya Patricia; Roumier Thomas; Andreau Karine; Gonzalez-Polo Rosa Ana; Zamzami Naoufal; Castedo Maria; Kroemer Guido
Mitochondrion-targeted apoptosis regulators of viral origin.
Biochemical and biophysical research communications 2003;304(3):575-81.
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2002: Castedo M; Perfettini J-L; Roumier T; Kroemer G
Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe.
Cell death and differentiation 2002;9(12):1287-93.
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2002: Castedo Maria; Perfettini Jean-Luc; Kroemer Guido
Mitochondrial apoptosis and the peripheral benzodiazepine receptor: a novel target for viral and pharmacological manipulation.
The Journal of experimental medicine 2002;196(9):1121-5.
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2002: Roumier T; Vieira H L A; Castedo M; Ferri K F; Boya P; Andreau K; Druillennec S; Joza N; Penninger J M; Roques B; Kroemer G
The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway.
Cell death and differentiation 2002;9(11):1212-9.
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2002: Haouzi D; Cohen I; Vieira H L A; Poncet D; Boya P; Castedo M; Vadrot N; Belzacq A-S; Fau D; Brenner C; Feldmann G; Kroemer G
Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo.
Apoptosis : an international journal on programmed cell death 2002;7(5):395-405.
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2002: Castedo Maria; Kroemer Guido
The beauty of death.
Trends in cell biology 2002;12(9):446.
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2002: Castedo Maria; Roumier Thomas; Blanco Julià; Ferri Karine F; Barretina Jordi; Tintignac Lionel A; Andreau Karine; Perfettini Jean-Luc; Amendola Alessandra; Nardacci Roberta; Leduc Philip; Ingber Donald E; Druillennec Sabine; Roques Bernard; Leibovitch Serge A; Vilella-Bach Montserrat; Chen Jie; Este José A; Modjtahedi Nazanine; Piacentini Mauro; Kroemer Guido
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope.
The EMBO journal 2002;21(15):4070-80.
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2002: Cohen Isabelle; Castedo Maria; Kroemer Guido
Tantalizing Thanatos: unexpected links in death pathways.
Trends in cell biology 2002;12(7):293-5.
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2002: Castedo Maria; Ferri Karine; Roumier Thomas; Métivier Didier; Zamzami Naoufal; Kroemer Guido
Quantitation of mitochondrial alterations associated with apoptosis.
Journal of immunological methods 2002;265(1-2):39-47.
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2002: Decaudin Didier; Castedo Maria; Nemati Fariba; Beurdeley-Thomas Arnaud; De Pinieux Gonzague; Caron Antoine; Pouillart Pierre; Wijdenes John; Rouillard Dany; Kroemer Guido; Poupon Marie-France
Peripheral benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo.
Cancer research 2002;62(5):1388-93.
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2002: Castedo M; Ferri K F; Kroemer G
Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
Cell death and differentiation 2002;9(2):99-100.
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2002: Costantini P; Bruey J-M; Castedo M; Métivier D; Loeffler M; Susin S A; Ravagnan L; Zamzami N; Garrido C; Kroemer Guido
Pre-processed caspase-9 contained in mitochondria participates in apoptosis.
Cell death and differentiation 2002;9(1):82-8.
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2001: Castedo M; Ferri K F; Blanco J; Roumier T; Larochette N; Barretina J; Amendola A; Nardacci R; Métivier D; Este J A; Piacentini M; Kroemer G
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation.
The Journal of experimental medicine 2001;194(8):1097-110.
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1997: Petit P X; Zamzami N; Vayssière J L; Mignotte B; Kroemer G; Castedo M
Implication of mitochondria in apoptosis.
Molecular and cellular biochemistry 1997;174(1-2):185-8.
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1997: Susin S A; Zamzami N; Castedo M; Daugas E; Wang H G; Geley S; Fassy F; Reed J C; Kroemer G
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis.
The Journal of experimental medicine 1997;186(1):25-37.
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1997: Decaudin D; Geley S; Hirsch T; Castedo M; Marchetti P; Macho A; Kofler R; Kroemer G
Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents.
Cancer research 1997;57(1):62-7.
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1996: Macho A; Decaudin D; Castedo M; Hirsch T; Susin S A; Zamzami N; Kroemer G
Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis.
Cytometry 1996;25(4):333-40.
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1996: Marchetti P; Hirsch T; Zamzami N; Castedo M; Decaudin D; Susin S A; Masse B; Kroemer G
Mitochondrial permeability transition triggers lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):4830-6.
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1996: Susin S A; Zamzami N; Castedo M; Hirsch T; Marchetti P; Macho A; Daugas E; Geuskens M; Kroemer G
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.
The Journal of experimental medicine 1996;184(4):1331-41.
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1996: Marchetti P; Castedo M; Susin S A; Zamzami N; Hirsch T; Macho A; Haeffner A; Hirsch F; Geuskens M; Kroemer G
Mitochondrial permeability transition is a central coordinating event of apoptosis.
The Journal of experimental medicine 1996;184(3):1155-60.
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1996: Ramírez R; Carracedo J; Castedo M; Zamzami N; Kroemer G
CD69-induced monocyte apoptosis involves multiple nonredundant signaling pathways.
Cellular immunology 1996;172(2):192-9.
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1996: Castedo M; Hirsch T; Susin S A; Zamzami N; Marchetti P; Macho A; Kroemer G
Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):512-21.
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1996: Marchetti P; Susin S A; Decaudin D; Gamen S; Castedo M; Hirsch T; Zamzami N; Naval J; Senik A; Kroemer G
Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.
Cancer research 1996;56(9):2033-8.
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1996: Zamzami N; Marchetti P; Castedo M; Hirsch T; Susin S A; Masse B; Kroemer G
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.
FEBS letters 1996;384(1):53-7.
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1996: Zamzami N; Susin S A; Marchetti P; Hirsch T; Gómez-Monterrey I; Castedo M; Kroemer G
Mitochondrial control of nuclear apoptosis.
The Journal of experimental medicine 1996;183(4):1533-44.
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1996: González-García A; Marchetti P; Castedo M; Zamzami N; Tarazona R; Martínez-A C; Kroemer G
Polyethylene glycol-modified IL-2 abrogates superantigen-induced anergy without affecting peripheral clonal deletion in vivo.
Clinical immunology and immunopathology 1996;78(3):215-22.
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1996: Rawadi G; Roman-Roman S; Castedo M; Dutilleul V; Susin S; Marchetti P; Geuskens M; Kroemer G
Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):670-8.
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1995: Castedo M; Macho A; Zamzami N; Hirsch T; Marchetti P; Uriel J; Kroemer G
Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo.
European journal of immunology 1995;25(12):3277-84.
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1995: Macho A; Castedo M; Marchetti P; Aguilar J J; Decaudin D; Zamzami N; Girard P M; Uriel J; Kroemer G
Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers.
Blood 1995;86(7):2481-7.
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1995: Zamzami N; Marchetti P; Castedo M; Decaudin D; Macho A; Hirsch T; Susin S A; Petit P X; Mignotte B; Kroemer G
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.
The Journal of experimental medicine 1995;182(2):367-77.
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1995: Zamzami N; Marchetti P; Castedo M; Zanin C; Vayssière J L; Petit P X; Kroemer G
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.
The Journal of experimental medicine 1995;181(5):1661-72.
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1995: Kroemer G; Zamzami N; Marchetti P; Castedo M
Maintenance of the T lymphocyte pool by inhibition of apoptosis: a novel strategy of immunostimulation?
Current topics in microbiology and immunology 1995;200():223-35.
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1994: Ramírez R; Carracedo J; Zamzami N; Castedo M; Kroemer G
Pertussis toxin inhibits activation-induced cell death of human thymocytes, pre-B leukemia cells and monocytes.
The Journal of experimental medicine 1994;180(3):1147-52.
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