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Rudy Castellani

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Oliver Tannous; Alec C Stall; Rudy J Castellani; Christopher T Donaldson; Cullen Griffith; Vincent D Pellegrini Jr
Heterotopic bone formation about the hip undergoes endochondral ossification: a rabbit model.
Irina S Balan; Rudy J Castellani; Hegang Chen; Howard M Eisenberg; Andrew Saladino; Deborah M Stein; Christine Wade; Bizhan Aarabi; Gary Fiskum
Cellular alterations in human traumatic brain injury: changes in mitochondrial morphology reflect regional levels of injury severity.
Rudy J Castellani; George Perry
Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress.

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2013: Oliver Tannous; Alec C Stall; Rudy J Castellani; Christopher T Donaldson; Cullen Griffith; Vincent D Pellegrini Jr
Heterotopic bone formation about the hip undergoes endochondral ossification: a rabbit model.
Clinical orthopaedics and related research 2013;471(5):1584-92.
2013: Irina S Balan; Rudy J Castellani; Hegang Chen; Howard M Eisenberg; Andrew Saladino; Deborah M Stein; Christine Wade; Bizhan Aarabi; Gary Fiskum
Cellular alterations in human traumatic brain injury: changes in mitochondrial morphology reflect regional levels of injury severity.
Journal of neurotrauma 2013;30(5):367-81.
2012: Rudy J Castellani; George Perry
Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress.
Archives of medical research 2012;43(8):694-8.
2012: Akihiko Nunomura; Rudy J Castellani; Hyoung-gon Lee; Paula I Moreira; Mark A Smith; Xiongwei Zhu; George Perry
Oxidative damage to RNA in aging and neurodegenerative disorders.
Neurotoxicity research 2012;22(3):231-48.
2012: Peter T Nelson; Julie A Schneider; Joshua A Sonnen; Dietmar R Thal; John Q Trojanowski; Juan C Troncoso; Thomas Wisniewski; Randall L Woltjer; Irina Alafuzoff; Eileen H Bigio; Constantin Bouras; Heiko Braak; Nigel J Cairns; Rudy J Castellani; Barbara J Crain; Peter Davies; Kelly Del Tredici; Charles Duyckaerts; Matthew P Frosch; Vahram Haroutunian; Patrick R Hof; Christine M Hulette; Bradley T Hyman; Takeshi Iwatsubo; Kurt A Jellinger; Gregory A Jicha; Enikö Kövari; Walter A Kukull; James B Leverenz; Seth Love; Ian R Mackenzie; David M Mann; Eliezer Masliah; Ann C McKee; Thomas J Montine; John C Morris; Thomas G Beach
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.
Journal of neuropathology and experimental neurology 2012;71(5):362-81.
2012: Xinglong Wang; Gemma Casadesus Smith; Rudy J Castellani; Eric Klann; Robert B Petersen; Avneet Singh; Mark A Smith; Mike Snape; Jeremy G Stone; Xiongwei Zhu
Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome.
Journal of neurochemistry 2012;121(4):672-9.
2012: Rudy J Castellani; Paula I Moreira; George Perry; Xiongwei Zhu
The role of iron as a mediator of oxidative stress in Alzheimer disease.
BioFactors (Oxford, England) 2012;38(2):133-8.
2012: Xiongwei Zhu; Nicholas P Ziats; Rudy J Castellani; Hyoung Gon Lee; Robert B Petersen; George Perry
Mark A. Smith: neurocytochemistry innovator.
Journal of neurochemistry 2012;120(6):1139-40.
2012: Xiongwei Zhu; Gjumrakch Aliev; Rudy J Castellani; Hisashi Fujioka; Peggy L R Harris; Paula I Moreira; Lawrence M Sayre; Justin Shenk; Sandra L Siedlak; Mark A Smith; Luke I Szweda; Pamela A Szweda; George Perry
Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.
Free radical biology & medicine 2012;52(3):699-704.
2012: Hari Shanker Sharma; Mark A Smith; Rudy J Castellani; Aruna Sharma
The blood-brain barrier in Alzheimer's disease: novel therapeutic targets and nanodrug delivery.
International review of neurobiology 2012;102():47-90.
2012: Wesley M Williams; Aaron Weinberg; Rudy J Castellani; George Perry; Mark A Smith
Do β-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration?
TheScientificWorldJournal 2012;2012():905785.
2012: George Perry; Robert B Petersen; CF Phelix; Rudy J Castellani; Luis V Colom; Hyoung-gon Lee; Akihiko Nunomura; Xiongwei Zhu
Untangling the vascular web from Alzheimer disease and oxidative stress.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2012;39(1):4.
2011: Michael T Koltz; David B Kurland; Cigdem Tosun; Rudy J Castellani; Turhan Coksaygan; Vladimir V Gerzanich; Svetlana Ivanova; J Marc Simard
Tandem insults of prenatal ischemia plus postnatal raised intrathoracic pressure in a novel rat model of encephalopathy of prematurity.
Journal of neurosurgery. Pediatrics 2011;8(6):628-39.
2011: Rudy J Castellani; Jeff M Coller; Yashi Gupta; Peggy Lr Harris; Hyoung-gon Lee; George Perry; Baiyang Sheng; Sandra L Siedlak; Mark A Smith; Massimo Tabaton; Xinglong Wang; Xiongwei Zhu
A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules.
Laboratory investigation; a journal of technical methods and pathology 2011;91(12):1777-86.
2011: Rudy J Castellani; Hyoung-gon Lee; Robert B Petersen; Xiongwei Zhu; George Perry
Mark A. Smith: the scientist, the man.
International journal of experimental pathology 2011;92(5):297-8.
2011: Xinglong Wang; Rudy J Castellani; Yuan Gao; Xiaohua He; Wanhong Liu; George Perry; Mark A. Smith; Bo Su; Xiongwei Zhu
DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease.
Aging cell 2011;10(5):807-23.
2011: D J Bonda; A Nunomura; George Perry; X Zhu; Rudy J Castellani; H-g Lee; M A Smith
A novel perspective on tau in Alzheimer's disease.
Current Alzheimer research 2011;8(6):639-42.
2011: Jeremy G Stone; Massimo Tabaton; Xiongwei Zhu; Rudy J Castellani; Asao Hirano; George Perry; Corrado Santocanale; Sandra L Siedlak; Mark A. Smith; Hyoung-gon Lee
The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies.
Journal of neuropathology and experimental neurology 2011;70(7):578-87.
2011: Rudy J Castellani; Mark A. Smith
Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is 'too big to fail'.
The Journal of pathology 2011;224(2):147-52.
2011: Rudy J Castellani
Obituary: Mark A Smith.
Expert review of neurotherapeutics 2011;11(3):463-4.
2011: William H Hoffman; Sandra L Siedlak; Yang Wang; Rudy J Castellani; Mark A. Smith
Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis.
Brain research 2011;1369():194-202.
2011: Nicholas P Ziats; Rudy J Castellani; Hyoung-gon Lee; George Perry; Robert B Petersen; Xiongwei Zhu
Mark A. Smith, 1965-2010: consummate student of pathogenesis.
International journal of clinical and experimental pathology 2011;4(7):731-2.
2011: Jeremy G Stone; Xinglong Wang; Xiongwei Zhu; Gemma Casadesus Smith; Rudy J Castellani; Kasia Gustaw-Rothenberg; George Perry; Sandra L Siedlak; Mark A Smith
Frontiers in Alzheimer's disease therapeutics.
Therapeutic advances in chronic disease 2011;2(1):9-23.
2011: Rudy J Castellani; Summer L Nugent; AL Morrison; Xiongwei Zhu; Hyoung-gon Lee; Peggy L R Harris; Vladan Bajić; Hari S Sharma; Shu G Chen; Peter Oettgen; George Perry; Mark A. Smith
CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(1):23-6.
2010: Jonathon E Heath; Sandra L Siedlak; Xiongwei Zhu; Hyoung-gon Lee; Akanksha Thakur; Riqiang Yan; George Perry; Mark A. Smith; Rudy J Castellani
Widespread distribution of reticulon-3 in various neurodegenerative diseases.
Neuropathology : official journal of the Japanese Society of Neuropathology 2010;30(6):574-9.
2010: John C Fyfe; Raba' A Al-Tamimi; Rudy J Castellani; Diana Rosenstein; Daniel Goldowitz; Paula S Henthorn
Inherited neuroaxonal dystrophy in dogs causing lethal, fetal-onset motor system dysfunction and cerebellar hypoplasia.
The Journal of comparative neurology 2010;518(18):3771-84.
2010: Rudy J Castellani; Raj K Rolston; Mark A. Smith
Alzheimer disease.
Disease-a-month : DM 2010;56(9):484-546.
2010: Reena S Shah; Robert K Shin; Rudy J Castellani
Granulocytic sarcoma mimicking HSV encephalitis.
The neurologist 2010;16(5):319-21.
2010: Marianna Shvartsbeyn; Daniel G K Phillips; Michael A Markey; Alan Morrison; Joyce L DeJong; Rudy J Castellani
Cocaine-induced intracerebral hemorrhage in a patient with cerebral amyloid angiopathy.
Journal of forensic sciences 2010;55(5):1389-92.
2010: Wen-Quan Zou; Gianfranco Puoti; Xiangzhu Xiao; Jue Yuan; Liuting Qing; Ignazio Cali; Miyuki Shimoji; Jan P M Langeveld; Rudy J Castellani; Silvio Notari; Barbara J Crain; Robert E Schmidt; Michael Geschwind; Stephen J DeArmond; Nigel J Cairns; dennis dickson; Lawrence Honig; Juan Maria Torres; James A Mastrianni; Sabina Capellari; Giorgio Giaccone; Ermias D Belay; Lawrence B Schonberger; Mark Cohen; George Perry; Qingzhong Kong; Piero Parchi; Fabrizio Tagliavini; Pierluigi Gambetti
Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.
Annals of neurology 2010;68(2):162-72.
2010: Calvin F Moh; Sandra L Siedlak; Massimo Tabaton; George Perry; Rudy J Castellani; Mark A. Smith
Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease.
Journal of neuroscience methods 2010;190(2):244-7.
2010: Hyun Pil Lee; Xiongwei Zhu; Gemma Casadesus; Rudy J Castellani; Akihiko Nunomura; Mark A. Smith; Hyoung-gon Lee; George Perry
Antioxidant approaches for the treatment of Alzheimer's disease.
Expert review of neurotherapeutics 2010;10(7):1201-8.
2010: Siddhartha Mondragón-Rodríguez; Gustavo Basurto-Islas; Hyoung-gon Lee; George Perry; Xiongwei Zhu; Rudy J Castellani; Mark A. Smith
Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis.
Expert review of neurotherapeutics 2010;10(5):683-91.
2010: David J Bonda; Maneesh Mailankot; Jeremy G Stone; Matthew R Garrett; Magdalena Staniszewska; Rudy J Castellani; Sandra L Siedlak; Xiongwei Zhu; Hyoung-gon Lee; George Perry; Ram H Nagaraj; Mark A. Smith
Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.
Redox report : communications in free radical research 2010;15(4):161-8.
2009: Ignazio Cali; Rudy J Castellani; Amer Alshekhlee; Yvonne Cohen; Janis Blevins; Jue Yuan; Jan P M Langeveld; Piero Parchi; Jiri G Safar; Wen-Quan Zou; Pierluigi Gambetti
Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics.
Brain : a journal of neurology 2009;132(Pt 10):2643-58.
2009: Akihiko Nunomura; Tim Hofer; Paula I Moreira; Rudy J Castellani; Mark A. Smith; George Perry
RNA oxidation in Alzheimer disease and related neurodegenerative disorders.
Acta neuropathologica 2009;118(1):151-66.
2009: David J Bonda; Teresa A Evans; Corrado Santocanale; Jesús Catalá Llosá; Jose Viña; Bajic Vladan; Rudy J Castellani; Sandra L Siedlak; George Perry; Mark A. Smith; Hyoung-gon Lee
Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease.
Aging 2009;1(4):382-8.
2009: Rudy J Castellani; Xiongwei Zhu; Hyoung-gon Lee; Mark A. Smith; George Perry
Molecular pathogenesis of Alzheimer's disease: Reductionist versus expansionist approaches.
International journal of molecular sciences 2009;10(3):1386-406.
2009: Luis F Gonzalez-Cuyar; Fabio Tavora; Kyle Shaw; Rudy J Castellani; Joyce L Dejong
Sudden unexpected death in lymphocytic hypophysitis.
The American journal of forensic medicine and pathology 2009;30(1):61-3.
2009: Hyoung-gon Lee; Gemma Casadesus Smith; Akihiko Nunomura; Xiongwei Zhu; Rudy J Castellani; Sandy L Richardson; George Perry; Dean W Felsher; Robert B Petersen; Mark A. Smith
The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.
The American journal of pathology 2009;174(3):891-7.
2009: Hyoung-gon Lee; Gemma Casadesus Smith; Xiongwei Zhu; Rudy J Castellani; Andy McShea; George Perry; Robert B Petersen; Bajic Vladan; Mark A. Smith
Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease.
Neurochemistry international 2009;54(2):84-8.
2009: Avi L Friedlich; Raj K Rolston; Xiongwei Zhu; Michael W Marlatt; Rudy J Castellani; Akihiko Nunomura; Hyoung-gon Lee; Gemma Casadesus; George Perry; Mark A. Smith
Treatment advances in Alzheimer's disease based on the oxidative stress model.
F1000 medicine reports 2009;1():.
2009: Hyoung-gon Lee; Qun Chen; Julie A Wolfram; Sandy L Richardson; Anna Liner; Sandra L Siedlak; Xiongwei Zhu; Nicholas P Ziats; Hisashi Fujioka; Dean W Felsher; Rudy J Castellani; Maria L Valencik; John A McDonald; Brian D Hoit; Edward J Lesnefsky; Mark A. Smith
Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure.
PloS one 2009;4(9):e7172.
2009: Bo Su; Haihua Liu; Xinglong Wang; Shu G Chen; Sandra L Siedlak; Eisaku Kondo; Raymond Choi; Atsushi Takeda; Rudy J Castellani; George Perry; Mark A. Smith; Xiongwei Zhu; Hyoung-gon Lee
Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease.
Molecular neurodegeneration 2009;4():32.
2009: Rudy J Castellani; Hyoung-gon Lee; Sandra L Siedlak; Akihiko Nunomura; Takaaki Hayashi; Masao Nakamura; Xiongwei Zhu; George Perry; Mark A. Smith
Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta.
Journal of Alzheimer's disease : JAD 2009;18(2):447-52.
2009: Jeremy G Stone; Raj K Rolston; Masumi Ueda; Hyoung-gon Lee; Sandy L Richardson; Rudy J Castellani; George Perry; Mark A. Smith
Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain.
International journal of clinical and experimental pathology 2009;2(3):267-74.
2008: Na-Hye Myung; Xiongwei Zhu; Inna I Kruman; Rudy J Castellani; Robert B Petersen; Sandra L Siedlak; George Perry; Mark A. Smith; Hyoung-gon Lee
Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes.
Age (Dordrecht, Netherlands) 2008;30(4):209-15.
2008: J Marc Simard; Rudy J Castellani; Svetlana Ivanova; Michael T Koltz; Vladimir V Gerzanich
Sulfonylurea receptor 1 in the germinal matrix of premature infants.
Pediatric research 2008;64(6):648-52.
2008: Luis F Gonzalez-Cuyar; George Perry; Hiroaki Miyajima; Craig S Atwood; Marcela Riveros-Angel; Patrick F Lyons; Sandra L Siedlak; Mark A. Smith; Rudy J Castellani
Redox active iron accumulation in aceruloplasminemia.
Neuropathology : official journal of the Japanese Society of Neuropathology 2008;28(5):466-71.
2008: Rudy J Castellani; Akihiko Nunomura; Hyoung-gon Lee; George Perry; Mark A. Smith
Phosphorylated tau: toxic, protective, or none of the above.
Journal of Alzheimer's disease : JAD 2008;14(4):377-83.
2008: Katarzyna A Gustaw; Matthew R Garrett; Hyoung-gon Lee; Rudy J Castellani; Michael G Zagorski; Annamalai Prakasam; Sandra L Siedlak; Xiongwei Zhu; George Perry; Robert B Petersen; Robert P Friedland; Mark A. Smith
Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis.
Journal of neurochemistry 2008;106(3):1350-6.
2008: Xiongwei Zhu; S L Siedlak; Yanming Wang; George Perry; Rudy J Castellani; M L Cohen; Mark A. Smith
Neuronal binucleation in Alzheimer disease hippocampus.
Neuropathology and applied neurobiology 2008;34(4):457-65.
2008: Pierluigi Gambetti; Zhiqian Dong; Jue Yuan; Xiangzhu Xiao; Mengjie Zheng; Amer Alshekhlee; Rudy J Castellani; Mark Cohen; Marcelo A Barria; D Gonzalez-Romero; Ermias D Belay; Lawrence B Schonberger; Karen Marder; Carrie Harris; James R Burke; Thomas J Montine; Thomas Wisniewski; dennis dickson; Claudio Soto; Christine M Hulette; James A Mastrianni; Qingzhong Kong; Wen-Quan Zou
A novel human disease with abnormal prion protein sensitive to protease.
Annals of neurology 2008;63(6):697-708.
2008: Rudy J Castellani; Hyoung-gon Lee; Xiongwei Zhu; George Perry; Mark A. Smith
Alzheimer disease pathology as a host response.
Journal of neuropathology and experimental neurology 2008;67(6):523-31.
2008: Rudy J Castellani; Akihiko Nunomura; Raj K Rolston; Paula I Moreira; Atsushi Takeda; George Perry; Mark A. Smith
Sublethal RNA oxidation as a mechanism for neurodegenerative disease.
International journal of molecular sciences 2008;9(5):789-806.
2008: Reena S Shah; Hyoung-gon Lee; Zhu Xiongwei; George Perry; Mark A. Smith; Rudy J Castellani
Current approaches in the treatment of Alzheimer's disease.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(4):199-207.
2008: Luis F Gonzalez-Cuyar; Dora Lam-Himlin; Fabio Tavora; Allen P Burke; Rudy J Castellani
Bilateral internal carotid absence: a case report of a rare congenital anomaly.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2008;17(2):113-6.
2008: Kathryn J Bryan; Xiongwei Zhu; Peggy L R Harris; George Perry; Rudy J Castellani; Mark A. Smith; Gemma Casadesus Smith
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease.
Molecular neurodegeneration 2008;3():13.
2008: George Perry; Rudy J Castellani; Paula I Moreira; Hyoung-gon Lee; Xiongwei Zhu; Mark A. Smith
Pathology's new role: defining disease process and protective responses.
International journal of clinical and experimental pathology 2008;1(1):1-4.
2007: Rudy J Castellani
Vascular dementia and Alzheimer's disease: a waning dichotomy.
Journal of Alzheimer's disease : JAD 2007;12(4):343-4.
2007: Akihiko Nunomura; Paula I Moreira; Hyoung-gon Lee; Xiongwei Zhu; Rudy J Castellani; Mark A. Smith; George Perry
Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases.
CNS & neurological disorders drug targets 2007;6(6):411-23.
2007: Rudy J Castellani; George Perry; Mark A. Smith
The role of novel chitin-like polysaccharides in Alzheimer disease.
Neurotoxicity research 2007;12(4):269-74.
2007: Mackenzie Carpenter; Christopher Polk; Rudy J Castellani; Karen Mochoruk; Stephen Sanche; Barney J Stern; Michael S Donnenberg
Encephalitis of the basal ganglia in an injection drug user.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;45(11):1479, 1522-4.
2007: Rudy J Castellani; Paula I Moreira; Gang Liu; Jon Dobson; George Perry; Mark A. Smith; Xiongwei Zhu
Iron: the Redox-active center of oxidative stress in Alzheimer disease.
Neurochemical research 2007;32(10):1640-5.
2007: Hyoung-gon Lee; Xiongwei Zhu; Rudy J Castellani; Akihiko Nunomura; George Perry; Mark A. Smith
Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses.
The Journal of pharmacology and experimental therapeutics 2007;321(3):823-9.
2007: Rudy J Castellani; Xiongwei Zhu; Hyoung-gon Lee; Paula I Moreira; George Perry; Mark A. Smith
Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?
Expert review of neurotherapeutics 2007;7(5):473-85.
2007: Laura A Previll; Meredith Crosby; Rudy J Castellani; Robert Bowser; George Perry; Mark A. Smith; Xiongwei Zhu
Increased expression of p130 in Alzheimer disease.
Neurochemical research 2007;32(4-5):639-44.
2007: Luis F Gonzalez-Cuyar; Brian Hunter; Peggy L R Harris; George Perry; Mark A. Smith; Rudy J Castellani
Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress.
Redox report : communications in free radical research 2007;12(3):119-24.
2006: Dora Lam-Himlin; Michael G Espey; George Perry; Mark A. Smith; Rudy J Castellani
Malignant glioma progression and nitric oxide.
Neurochemistry international 2006;49(8):764-8.
2006: Ignazio Cali; Rudy J Castellani; Jue Yuan; Amer Al-Shekhlee; Mark L Cohen; Xiangzhu Xiao; Francisco J Moleres; Piero Parchi; Wen-Quan Zou; Pierluigi Gambetti
Classification of sporadic Creutzfeldt-Jakob disease revisited.
Brain : a journal of neurology 2006;129(Pt 9):2266-77.
2006: Varsha Manucha; Rudy J Castellani; Chen-Chih Sun
Alveolar rhabdomyosarcoma of the paranasal sinuses in a 57-year-old woman with 1:16 translocation.
International journal of surgical pathology 2006;14(3):238-42.
2006: Akihiko Nunomura; Rudy J Castellani; Xiongwei Zhu; Paula I Moreira; George Perry; Mark A. Smith
Involvement of oxidative stress in Alzheimer disease.
Journal of neuropathology and experimental neurology 2006;65(7):631-41.
2006: Rudy J Castellani; Hyoung-gon Lee; Xiongwei Zhu; Akihiko Nunomura; George Perry; Mark A. Smith
Neuropathology of Alzheimer disease: pathognomonic but not pathogenic.
Acta neuropathologica 2006;111(6):503-9.
2006: Akihiko Nunomura; Rudy J Castellani; Hyoung-gon Lee; Paula I Moreira; Xiongwei Zhu; George Perry; Mark A. Smith
Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream.
Science of aging knowledge environment : SAGE KE 2006;2006(8):pe10.
2006: Mark A Smith; Xiongwei Zhu; Anne E Fortino; Peggy L R Harris; Hyoung-gon Lee; George Perry; Rudy J Castellani
Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy.
Age (Dordrecht, Netherlands) 2006;28(1):85-91.
2006: Rudy J Castellani; Hyoung-gon Lee; George Perry; Mark A. Smith
Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau.
American journal of Alzheimer's disease and other dementias 2006;21(2):126-30.
2005: Rudy J Castellani; Sandra L Siedlak; Anne E Fortino; George Perry; Bernardino Ghetti; Mark A. Smith
Chitin-like polysaccharides in Alzheimer's disease brains.
Current Alzheimer research 2005;2(4):419-23.
2005: Robert B Petersen; Sandra L Siedlak; Hyoung-gon Lee; Yong-Sun Kim; Akihiko Nunomura; Fabrizio Tagliavini; Bernardino Ghetti; Patrick Cras; Paula I Moreira; Rudy J Castellani; Marin Guentchev; Herbert Budka; James W Ironside; Pierluigi Gambetti; Mark A. Smith; George Perry
Redox metals and oxidative abnormalities in human prion diseases.
Acta neuropathologica 2005;110(3):232-8.
2005: Roberto Luksch; Marta Podda; Lorenza Gandola; Daniela Polastri; Luigi Piva; Rudy J Castellani; Paola Collini; maura massimino; Graziella Cefalo; Monica Terenziani; Andrea Ferrari; Michela Casanova; Filippo Spreafico; Cristina Meazza; Fabio Bozzi; Alfonso Marchianò; Fernando Ravagnani; Franca Fossati-Bellani
Stage 4 neuroblastoma: sequential hemi-body irradiation or high-dose chemotherapy plus autologous haemopoietic stem cell transplantation to consolidate primary treatment.
British journal of cancer 2005;92(11):1984-8.
2005: Paula I Moreira; Mark A. Smith; Xiongwei Zhu; Akihiko Nunomura; Rudy J Castellani; George Perry
Oxidative stress and neurodegeneration.
Annals of the New York Academy of Sciences 2005;1043():545-52.
2005: Hyoung-gon Lee; Rudy J Castellani; Xiongwei Zhu; George Perry; Mark A. Smith
Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?
International journal of experimental pathology 2005;86(3):133-8.
2005: Qianchuan He; Charles Lowrie; G Diane Shelton; Rudy J Castellani; Marilyn Menotti-Raymond; William Murphy; Stephen J O'Brien; William F Swanson; John C Fyfe
Inherited motor neuron disease in domestic cats: a model of spinal muscular atrophy.
Pediatric research 2005;57(3):324-30.
2004: Rudy J Castellani; Monica Colucci; Zhiliang Xie; Wenquan Zou; Chaoyang Li; Piero Parchi; Sabina Capellari; Manuela Pastore; M H Rahbar; Shu G Chen; Pierluigi Gambetti
Sensitivity of 14-3-3 protein test varies in subtypes of sporadic Creutzfeldt-Jakob disease.
Neurology 2004;63(3):436-42.
2004: Gjumrakch Aliev; Rudy J Castellani; Robert B Petersen; G Burnstock; George Perry; Mark A. Smith
Pathobiology of familial hypercholesterolemic atherosclerosis.
Journal of submicroscopic cytology and pathology 2004;36(3-4):225-40.
2004: Rudy J Castellani; Kazuhiro Honda; Xiongwei Zhu; Adam D Cash; Akihiko Nunomura; George Perry; Mark A. Smith
Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease.
Ageing research reviews 2004;3(3):319-26.
2004: Rudy J Castellani; Mark A. Smith; George Perry; Robert P Friedland
Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis.
Neurobiology of aging 2004;25(5):599-602; discussion 603-4.
2004: Linjuan Huang; Rawle I Hollingsworth; Rudy J Castellani; Birgit Zipser
Accumulation of high-molecular-weight amylose in Alzheimer's disease brains.
Glycobiology 2004;14(5):409-16.
2004: Hyoung-gon Lee; Osamu Ogawa; Xiongwei Zhu; Michael J O'Neill; Robert B Petersen; Rudy J Castellani; Hossein A Ghanbari; George Perry; Mark A. Smith
Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease.
Acta neuropathologica 2004;107(4):365-71.
2004: Xiongwei Zhu; Andy McShea; Peggy L R Harris; Arun K Raina; Rudy J Castellani; Jens Oliver Funk; Sapan Shah; Craig S Atwood; Richard Bowen; Robert Bowser; Laura Morelli; George Perry; Mark A. Smith
Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease.
Journal of neuroscience research 2004;75(5):698-703.
2004: Hossein A Ghanbari; Kasra Ghanbari; Peggy L R Harris; Paul K Jones; Zvezdana Kubat; Rudy J Castellani; Benjamin Wolozin; Mark A. Smith; George Perry
Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients.
Aging cell 2004;3(1):41-4.
2004: Rudy J Castellani; George Perry; Mark A. Smith
Prion disease and Alzheimer's disease: pathogenic overlap.
Acta neurobiologiae experimentalis 2004;64(1):11-7.
2003: George Perry; Rudy J Castellani; Mark A. Smith; Peggy L R Harris; Zvezdana Kubat; Kasra Ghanbari; Paul K Jones; Giovanni Cordone; Massimo Tabaton; Benjamin Wolozin; Hossein A Ghanbari
Oxidative damage in the olfactory system in Alzheimer's disease.
Acta neuropathologica 2003;106(6):552-6.
2003: Adam D Cash; Gjumrakch Aliev; Sandra L Siedlak; Akihiko Nunomura; Hisashi Fujioka; Xiongwei Zhu; Arun K Raina; Harry V Vinters; Massimo Tabaton; Anne B Johnson; Manuel M Paula-Barbosa; Jesus Avíla; Paul K Jones; Rudy J Castellani; Mark A. Smith; George Perry
Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation.
The American journal of pathology 2003;162(5):1623-7.
2003: Osamu Ogawa; Xiongwei Zhu; Hyoung-gon Lee; Arun K Raina; Mark E Obrenovich; Robert Bowser; Hossein A Ghanbari; Rudy J Castellani; George Perry; Mark A. Smith
Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?
Acta neuropathologica 2003;105(5):524-8.
2003: Osamu Ogawa; Hyoung-gon Lee; Xiongwei Zhu; Arun K Raina; Peggy L R Harris; Rudy J Castellani; George Perry; Mark A. Smith
Increased p27, an essential component of cell cycle control, in Alzheimer's disease.
Aging cell 2003;2(2):105-10.
2003: Thomas A Krefft; Neill R Graff-Radford; dennis dickson; Matt Baker; Rudy J Castellani
Familial primary progressive aphasia.
Alzheimer disease and associated disorders 2003;17(2):106-12.
2003: George Perry; Marta A Taddeo; Robert B Petersen; Rudy J Castellani; Peggy L R Harris; Sandra L Siedlak; Adam D Cash; Quan Liu; Akihiko Nunomura; Craig S Atwood; Mark A. Smith
Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2003;16(1):77-81.
2002: George Perry; Marta A Taddeo; Akihiko Nunomura; Xiongwei Zhu; Tania Zenteno-Savin; Kelly L Drew; Shun Shimohama; Jesús Avila; Rudy J Castellani; Mark A. Smith
Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2002;133(4):507-13.
2002: George Perry; Akihiko Nunomura; Keisuke Hirai; Xiongwei Zhu; Mar Pérez; Jesús Avila; Rudy J Castellani; Craig S Atwood; Gjumrakch Aliev; Lawrence M Sayre; Atsushi Takeda; Mark A. Smith
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
Free radical biology & medicine 2002;33(11):1475-9.
2002: Akihiko Nunomura; Shigeru Chiba; Kenji Kosaka; Atsushi Takeda; Rudy J Castellani; Mark A. Smith; George Perry
Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies.
Neuroreport 2002;13(16):2035-9.
2002: Richard L Bowen; Mark A. Smith; Peggy L R Harris; Zvezdana Kubat; Ralph N Martins; Rudy J Castellani; George Perry; Craig S Atwood
Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology.
Journal of neuroscience research 2002;70(3):514-8.
2002: Rudy J Castellani; Keisuke Hirai; Gjumrakch Aliev; Kelly L Drew; Akihiko Nunomura; Atsushi Takeda; Adam D Cash; Mark E Obrenovich; George Perry; Mark A. Smith
Role of mitochondrial dysfunction in Alzheimer's disease.
Journal of neuroscience research 2002;70(3):357-60.
2002: Fang Zhou; Joan F Braddock; Yong Hu; Xiongwei Zhu; Rudy J Castellani; Mark A. Smith; Kelly L Drew
Microbial origin of glutamate, hibernation and tissue trauma: an in vivo microdialysis study.
Journal of neuroscience methods 2002;119(2):121-8.
2002: Anthony W Hartzler; Xiongwei Zhu; Sandra L Siedlak; Rudy J Castellani; Jesús Avila; George Perry; Mark A. Smith
The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.
Neurobiology of aging 2002;23(5):855-9.
2002: Marin Guentchev; Sandra L Siedlak; Christa Jarius; Fabrizio Tagliavini; Rudy J Castellani; George Perry; Mark A. Smith; Herbert Budka
Oxidative damage to nucleic acids in human prion disease.
Neurobiology of disease 2002;9(3):275-81.
2002: Akio Kikuchi; Atsushi Takeda; Hiroshi Onodera; Teiko Kimpara; Kinya Hisanaga; Nobuyuki Sato; Akihiko Nunomura; Rudy J Castellani; George Perry; Mark A. Smith; Yasuto Itoyama
Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy.
Neurobiology of disease 2002;9(2):244-8.
2002: Rudy J Castellani; George Perry; Sandra L Siedlak; Akihiko Nunomura; Shun Shimohama; Jing Zhang; Thomas J Montine; Lawrence M Sayre; Mark A. Smith
Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans.
Neuroscience letters 2002;319(1):25-8.
2002: Venetia R Sarode; Rudy J Castellani; Anthony Post
Fine-needle aspiration cytology and differential diagnoses of fibrolamellar hepatocellular carcinoma metastatic to the mediastinum: case report.
Diagnostic cytopathology 2002;26(2):95-8.
2002: George Perry; Lawrence M Sayre; Craig S Atwood; Rudy J Castellani; Adam D Cash; Catherine A Rottkamp; Mark A. Smith
The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications.
CNS drugs 2002;16(5):339-52.
2002: Harris Yfantis; Daisuke Nonaka; Rudy J Castellani; Christopher R Harman; Chen-Chih Sun
Heterogeneity in fetal akinesia deformation sequence (FADS): autopsy confirmation in three 20-21-week fetuses.
Prenatal diagnosis 2002;22(1):42-7.
2001: Xiongwei Zhu; Rudy J Castellani; Atsushi Takeda; Akihiko Nunomura; Craig S Atwood; George Perry; Mark A. Smith
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.
Mechanisms of ageing and development 2001;123(1):39-46.
2001: Rudy J Castellani; Peggy L R Harris; Lawrence M Sayre; J Fujii; N Taniguchi; Michael P. Vitek; H Founds; Craig S Atwood; George Perry; Mark A. Smith
Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine.
Free radical biology & medicine 2001;31(2):175-80.
2001: F Zhou; Xiongwei Zhu; Rudy J Castellani; R Stimmelmayr; George Perry; Mark A. Smith; Kelly L Drew
Hibernation, a model of neuroprotection.
The American journal of pathology 2001;158(6):2145-51.
2001: Arun K Raina; A Hochman; Xiongwei Zhu; Catherine A Rottkamp; Akihiko Nunomura; Sandra L Siedlak; H Boux; Rudy J Castellani; George Perry; Mark A. Smith
Abortive apoptosis in Alzheimer's disease.
Acta neuropathologica 2001;101(4):305-10.
2001: Rudy J Castellani; GN Wolffe; HH Renggli
Pocket elimination surgery with simultaneous connective tissue graft. A case report with 3-year follow-up.
Journal of clinical periodontology 2001;28(4):365-71.
2000: Rudy J Castellani; Sandra L Siedlak; George Perry; Mark A. Smith
Sequestration of iron by Lewy bodies in Parkinson's disease.
Acta neuropathologica 2000;100(2):111-4.
2000: Darius Rastegar; Rudy J Castellani
A 78-year-old woman with leg pain and weakness.
The American journal of the medical sciences 2000;319(6):404-10.
2000: Rudy J Castellani; Peggy L R Harris; Anne Lecroisey; Nadia Izadi-Pruneyre; Cécile Wandersman; George Perry; Mark A. Smith
Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease.
Antioxidants & redox signaling 2000;2(1):137-42.
2000: Daniele Pontillo; Aldo Capezzuto; Rudy J Castellani
Acute generalized urticaria leading to acute myocardial infarction.
Angiology 2000;51(1):89-90.
1999: Rudy J Castellani; George Perry; David S Brenner; Mark A. Smith
Alexander disease: Alzheimer disease of the developing brain?
Alzheimer disease and associated disorders 1999;13(4):232-5.
1999: Rudy J Castellani; Mark A. Smith; Akihiko Nunomura; Peggy L R Harris; George Perry
Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?
Free radical biology & medicine 1999;26(11-12):1508-12.
1999: Daniel J Brat; C D James; Anne E Jedlicka; D C Connolly; E Chang; Rudy J Castellani; M Schmid; M Schiller; D A Carson; Peter C Burger
Molecular genetic alterations in radiation-induced astrocytomas.
The American journal of pathology 1999;154(5):1431-8.
1999: JL Gerst; Sandra L Siedlak; Akihiko Nunomura; Rudy J Castellani; George Perry; Mark A. Smith
Role of oxidative stress in frontotemporal dementia.
Dementia and geriatric cognitive disorders 1999;10 Suppl 1():85-7.
1998: Mark A. Smith; Milan Vasák; Markus Knipp; Rudy J Castellani; George Perry
Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease.
Free radical biology & medicine 1998;25(8):898-902.
1998: Rudy J Castellani
Multiple system atrophy: clues from inclusions.
The American journal of pathology 1998;153(3):671-6.
1998: Michael T. Zagardo; Rudy J Castellani; J H Rees; MI Rothman; Gregg H Zoarski
Radiologic and pathologic findings of intracerebral schwannoma.
AJNR. American journal of neuroradiology 1998;19(7):1290-3.
1998: Rudy J Castellani; George Perry; Peggy L R Harris; M L Cohen; Lawrence M Sayre; R G Salomon; Mark A. Smith
Advanced lipid peroxidation end-products in Alexander's disease.
Brain research 1998;787(1):15-8.
1997: Cinthia Drachenberg; Olga B Ioffe; Rudy J Castellani; John C Papadimitriou
Nuclear bcl-2 staining in tumors.
American journal of clinical pathology 1997;108(4):479.
1997: Rudy J Castellani; George Perry; Peggy L R Harris; V M Monnier; M L Cohen; Mark A. Smith
Advanced glycation modification of Rosenthal fibers in patients with Alexander disease.
Neuroscience letters 1997;231(2):79-82.
1997: Pietro Cortelli; Daniela Perani; Piero Parchi; F Grassi; Pasquale Montagna; M De Martin; Rudy J Castellani; Paolo Tinuper; Pierluigi Gambetti; Elio Lugaresi; F Fazio
Cerebral metabolism in fatal familial insomnia: relation to duration, neuropathology, and distribution of protease-resistant prion protein.
Neurology 1997;49(1):126-33.
1997: Michael T. Zagardo; Rudy J Castellani; Gregg H Zoarski; S C Bauserman
Granulomatous amebic encephalitis caused by leptomyxid amebae in an HIV-infected patient.
AJNR. American journal of neuroradiology 1997;18(5):903-8.
1997: Rudy J Castellani; Piero Parchi; L Madoff; P Gambetti; P McKeever
Biopsy diagnosis of Creutzfeldt-Jakob disease by western blot: a case report.
Human pathology 1997;28(5):623-6.
1996: Rudy J Castellani; Mark A. Smith; P L Richey; George Perry
Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease.
Brain research 1996;737(1-2):195-200.
1996: Piero Parchi; Rudy J Castellani; Sabina Capellari; Bernardino Ghetti; K Young; Shu G Chen; Martin R Farlow; dennis dickson; Anders A F Sima; John Q Trojanowski; Robert B Petersen; Pierluigi Gambetti
Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease.
Annals of neurology 1996;39(6):767-78.
1996: Rudy J Castellani; Piero Parchi; J Stahl; Sabina Capellari; M Cohen; Pierluigi Gambetti
Early pathologic and biochemical changes in Creutzfeldt-Jakob disease: study of brain biopsies.
Neurology 1996;46(6):1690-3.
1996: Roberto Gallassi; A Morreale; Pasquale Montagna; Pietro Cortelli; Patrizia Avoni; Rudy J Castellani; Pierluigi Gambetti; Elio Lugaresi
Fatal familial insomnia: behavioral and cognitive features.
Neurology 1996;46(4):935-9.
1996: P Kim; Rudy J Castellani; N Tresser
Cerebral venous malformation complicated by spontaneous thrombosis.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 1996;12(3):172-5.
1995: Rudy J Castellani; Mark A. Smith; P L Richey; Rajesh N. Kalaria; Pierluigi Gambetti; George Perry
Evidence for oxidative stress in Pick disease and corticobasal degeneration.
Brain research 1995;696(1-2):268-71.
1995: DR Premkumar; Mark A. Smith; P L Richey; Robert B Petersen; Rudy J Castellani; R K Kutty; B Wiggert; George Perry; Rajesh N. Kalaria
Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease.
Journal of neurochemistry 1995;65(3):1399-402.
1995: Piero Parchi; Rudy J Castellani; Pietro Cortelli; Pasquale Montagna; Shu G Chen; Robert B Petersen; V Manetto; Cindy L Vnencak-Jones; Michael J McLean; J R Sheller
Regional distribution of protease-resistant prion protein in fatal familial insomnia.
Annals of neurology 1995;38(1):21-9.
1995: P Hedera; Alan J Lerner; Rudy J Castellani; Robert P Friedland
Concurrence of Alzheimer's disease, Parkinson's disease, diffuse Lewy body disease, and amyotrophic lateral sclerosis.
Journal of the neurological sciences 1995;128(2):219-24.
1994: Rudy J Castellani; Daniel W Visscher; S Wykes; Asfar S Azmi; JD Crissman
Interaction of transforming growth factor-alpha and epidermal growth factor receptor in breast carcinoma. An immunohistologic study.
Cancer 1994;73(2):344-9.
1993: Daniel W Visscher; Rudy J Castellani; S M Wykes; Asfar S Azmi; M E Hussain
Concurrent abnormal expression of ERBB-2, EGFR, and p53 genes and clinical disease progression of breast carcinoma.
Breast cancer research and treatment 1993;28(3):261-6.
1993: Emilio Bajetta; Nicoletta Zilembo; Maria Di Bartolomeo; A Di Leo; Silvana Pilotti; A M Bochicchio; Rudy J Castellani; Roberto Buzzoni; Luigi Celio; L Dogliotti
Treatment of metastatic carcinoids and other neuroendocrine tumors with recombinant interferon-alpha-2a. A study by the Italian Trials in Medical Oncology Group.
Cancer 1993;72(10):3099-105.
1993: Nicoletta Zilembo; Roberto Buzzoni; Emilio Bajetta; Maria Di Bartolomeo; Filippo de Braud; Rudy J Castellani; Lorenzo Maffioli; Luigi Celio; E Villa; V Lorusso
Salvage treatment after r-interferon alpha-2a in advanced neuroendocrine tumors.
Acta oncologica (Stockholm, Sweden) 1993;32(2):245-50.