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Stephan Hjorth

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Marie Wennerberg; Leifeng Cheng; Stephan Hjorth; John C Clapham; Anudharan Balendran; Georges Vauquelin
Binding properties of antagonists to cannabinoid receptors in intact cells.
Jonas Boström; Roine I Olsson; Joakim Tholander; Peter J Greasley; Erik Ryberg; Henrik Nordberg; Stephan Hjorth; Leifeng Cheng
Novel thioamide derivatives as neutral CB1 receptor antagonists.
E Lindström; A Ravnefjord; M Brusberg; Stephan Hjorth; H Larsson; V Martinez
The selective 5-hydroxytryptamine 1A antagonist, AZD7371 [3(R)-(N,N-dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide (R,R)-tartrate monohydrate] (robalzotan tartrate monohydrate), inhibits visceral pain-related visceromotor, but not autonomic cardiovascular, responses to colorectal distension in rats.

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All Publications

2011: Marie Wennerberg; Leifeng Cheng; Stephan Hjorth; John C Clapham; Anudharan Balendran; Georges Vauquelin
Binding properties of antagonists to cannabinoid receptors in intact cells.
Fundamental & clinical pharmacology 2011;25(2):200-10.
2010: Jonas Boström; Roine I Olsson; Joakim Tholander; Peter J Greasley; Erik Ryberg; Henrik Nordberg; Stephan Hjorth; Leifeng Cheng
Novel thioamide derivatives as neutral CB1 receptor antagonists.
Bioorganic & medicinal chemistry letters 2010;20(2):479-82.
2009: E Lindström; A Ravnefjord; M Brusberg; Stephan Hjorth; H Larsson; V Martinez
The selective 5-hydroxytryptamine 1A antagonist, AZD7371 [3(R)-(N,N-dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide (R,R)-tartrate monohydrate] (robalzotan tartrate monohydrate), inhibits visceral pain-related visceromotor, but not autonomic cardiovascular, responses to colorectal distension in rats.
The Journal of pharmacology and experimental therapeutics 2009;329(3):1048-55.
2007: E Ryberg; Niklas Larsson; S Sjögren; Stephan Hjorth; N-O Hermansson; J Leonova; Thomas Elebring; Karolina Nilsson; T Drmota; Peter J Greasley
The orphan receptor GPR55 is a novel cannabinoid receptor.
British journal of pharmacology 2007;152(7):1092-101.
2005: Erik Ryberg; Huy Khang Vu; Niklas Larsson; Thierry Groblewski; Stephan Hjorth; Thomas Elebring; Sven Sjögren; Peter J Greasley
Identification and characterisation of a novel splice variant of the human CB1 receptor.
FEBS letters 2005;579(1):259-64.
2004: Mohammad Bohlooly-Y; Margit Mahlapuu; Harriet Andersén; Annika Astrand; Stephan Hjorth; Lennart Svensson; Jan Törnell; Michael Snaith; David G Morgan; Claes Ohlsson
Osteoporosis in MCHR1-deficient mice.
Biochemical and biophysical research communications 2004;318(4):964-9.
2003: Tracy M Felton; Tommy B Kang; Stephan Hjorth; Sidney B Auerbach
Effects of selective serotonin and serotonin/noradrenaline reuptake inhibitors on extracellular serotonin in rat diencephalon and frontal cortex.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(3):297-305.
2002: Cecilia Wikell; Gustav Apelqvist; Stephan Hjorth; Johan Kullingsjö; Peter B F Bergqvist; Finn Bengtsson
Effects on drug disposition, brain monoamines and behavior after chronic treatment with the antidepressant venlafaxine in rats with experimental hepatic encephalopathy.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2002;12(4):327-36.
2001: Cecilia Wikell; Fredrik C Kugelberg; Stephan Hjorth; Gustav Apelqvist; Finn Bengtsson
Effect of halving the dose of venlafaxine to adjust for putative pharmacokinetic and pharmacodynamic changes in an animal model of chronic hepatic encephalopathy.
Clinical neuropharmacology 2001;24(6):324-33.
2001: Cecilia Wikell; Stephan Hjorth; Gustav Apelqvist; J Kullingsjö; Jöns Lundmark; Peter B F Bergqvist; Finn Bengtsson
Sustained administration of the antidepressant venlafaxine in rats: pharmacokinetic and pharmacodynamic findings.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(4):448-55.
2000: Gustav Apelqvist; Cecilia Wikell; Björn Carlsson; Stephan Hjorth; Peter B F Bergqvist; Johan Ahlner; Finn Bengtsson
Dynamic and kinetic effects of chronic citalopram treatment in experimental hepatic encephalopathy.
Clinical neuropharmacology 2000;23(6):304-17.
2000: HJ Bengtsson; J Kele; J Johansson; Stephan Hjorth
Interaction of the antidepressant mirtazapine with alpha2-adrenoceptors modulating the release of 5-HT in different rat brain regions in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(4-5):406-12.
2000: Stephan Hjorth; HJ Bengtsson; A Kullberg; D Carlzon; H Peilot; Sidney B Auerbach
Serotonin autoreceptor function and antidepressant drug action.
Journal of psychopharmacology (Oxford, England) 2000;14(2):177-85.
1999: Cecilia Wikell; Gustav Apelqvist; Björn Carlsson; Stephan Hjorth; Peter B F Bergqvist; Fredrik C Kugelberg; Johan Ahlner; Finn Bengtsson
Pharmacokinetic and pharmacodynamic responses to chronic administration of the selective serotonin reuptake inhibitor citalopram in rats.
Clinical neuropharmacology 1999;22(6):327-36.
1999: Stephan Hjorth; Sidney B Auerbach
Autoreceptors remain functional after prolonged treatment with a serotonin reuptake inhibitor.
Brain research 1999;835(2):224-8.
1998: Peter Martin; Maria L Carlsson; Stephan Hjorth
Systemic PCP treatment elevates brain extracellular 5-HT: a microdialysis study in awake rats.
Neuroreport 1998;9(13):2985-8.
1998: Cecilia Wikell; Peter B F Bergqvist; Stephan Hjorth; Gustav Apelqvist; H Björk; Finn Bengtsson
Brain monoamine output alterations after a single venlafaxine challenge in experimental hepatic encephalopathy.
Clinical neuropharmacology 1998;21(5):296-306.
1998: HJ Bengtsson; A Kullberg; M J Millan; Stephan Hjorth
The role of 5-HT1A autoreceptors and alpha1-adrenoceptors in the modulation of 5-HT release--III. Clozapine and the novel putative antipsychotic S 16924.
Neuropharmacology 1998;37(3):349-56.
1997: Peter B F Bergqvist; Cecilia Wikell; Stephan Hjorth; Gustav Apelqvist; Finn Bengtsson
Effect of citalopram on brain serotonin release in experimental hepatic encephalopathy: implications for thymoleptic drug safety in liver insufficiency.
Clinical neuropharmacology 1997;20(6):511-22.
1997: Peter B F Bergqvist; Stephan Hjorth; Cecilia Wikell; Gustav Apelqvist; Finn Bengtsson
p-Chloroamphetamine- and d-fenfluramine-induced brain serotonin release in experimental portal-systemic encephalopathy.
Metabolic brain disease 1997;12(3):229-36.
1997: Peter B F Bergqvist; Stephan Hjorth; Gustav Apelqvist; Finn Bengtsson
Potassium-evoked neuronal release of serotonin in experimental chronic portal-systemic encephalopathy.
Metabolic brain disease 1997;12(3):193-202.
1997: Mark J Millan; Stephan Hjorth; R Samanin; rudy schreiber; Robert Jaffard; B De Ladonchamps; Sylvie Veiga; B Goument; Jean-Louis Peglion; Michael Spedding; Mauricette Brocco
S 15535, a novel benzodioxopiperazine ligand of serotonin (5-HT)1A receptors: II. Modulation of hippocampal serotonin release in relation to potential anxiolytic properties.
The Journal of pharmacology and experimental therapeutics 1997;282(1):148-61.
1997: C Gundlah; Stephan Hjorth; Sidney B Auerbach
Autoreceptor antagonists enhance the effect of the reuptake inhibitor citalopram on extracellular 5-HT: this effect persists after repeated citalopram treatment.
Neuropharmacology 1997;36(4-5):475-82.
1997: Stephan Hjorth; D Westlin; HJ Bengtsson
WAY100635-induced augmentation of the 5-HT-elevating action of citalopram: relative importance of the dose of the 5-HT1A (auto)receptor blocker versus that of the 5-HT reuptake inhibitor.
Neuropharmacology 1997;36(4-5):461-5.
1996: Stephan Hjorth; HJ Bengtsson; S Milano
Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo.
European journal of pharmacology 1996;316(1):43-7.
1996: Peter B F Bergqvist; Stephan Hjorth; Robert Audet; Gustav Apelqvist; Finn Bengtsson; R F Butterworth
Ammonium acetate challenge in experimental chronic hepatic encephalopathy induces a transient increase of brain 5-HT release in vivo.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1996;6(4):317-22.
1996: Peter B F Bergqvist; Stephan Hjorth; Gustav Apelqvist; Finn Bengtsson
Acute effects of L-tryptophan on brain extracellular 5-HT and 5-HIAA levels in chronic experimental portal-systemic encephalopathy.
Metabolic brain disease 1996;11(3):269-78.
1996: M H Hedberg; T Linnanen; J M Jansen; Gunnar Nordvall; Stephan Hjorth; L Unelius; Anette M Johansson
11-substituted (R)-aporphines: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions.
Journal of medicinal chemistry 1996;39(18):3503-13.
1996: M H Hedberg; J M Jansen; Gunnar Nordvall; Stephan Hjorth; L Unelius; Anette M Johansson
10-substituted 11-oxygenated (R)-aporphines: synthesis, pharmacology, and modeling of 5-HT1A receptor interactions.
Journal of medicinal chemistry 1996;39(18):3491-502.
1996: Trevor Sharp; V Umbers; Stephan Hjorth
The role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--II NAN-190 and SDZ 216-525.
Neuropharmacology 1996;35(6):735-41.
1996: Stephan Hjorth
(-)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine.
European journal of pharmacology 1996;303(3):183-6.
1996: J Vallgårda; U Appelberg; L E Arvidsson; Stephan Hjorth; B E Svensson; Uli Hacksell
trans-2-Aryl-N,N-dipropylcyclopropylamines: synthesis and interactions with 5-HT(1A) receptors.
Journal of medicinal chemistry 1996;39(7):1485-93.
1996: Stephan Hjorth; S B Auerbach
5-HT1A autoreceptors and the mode of action of selective serotonin reuptake inhibitors (SSRI).
Behavioural brain research 1996;73(1-2):281-3.
1995: Sidney B Auerbach; Stephan Hjorth
Effect of chronic administration of the selective serotonin (5-HT) uptake inhibitor citalopram on extracellular 5-HT and apparent autoreceptor sensitivity in rat forebrain in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(6):597-606.
1995: Stephan Hjorth; HJ Bengtsson; S Milano; J F Lundberg; T Sharp
Studies on the role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--I. BMY7378 and prazosin.
Neuropharmacology 1995;34(6):615-20.
1995: Jianhua Zhang; Jörgen A Engel; Stephan Hjorth; Lennart Svensson
Changes in the acoustic startle response and prepulse inhibition of acoustic startle in rats after local injection of pertussis toxin into the ventral tegmental area.
Psychopharmacology 1995;119(1):71-8.
1995: Stephan Hjorth; C S Suchowski; matthew galloway
Evidence for 5-HT autoreceptor-mediated, nerve impulse-independent, control of 5-HT synthesis in the rat brain.
Synapse (New York, N.Y.) 1995;19(3):170-6.
1995: Peter B F Bergqvist; BA Vogels; D K Bosman; MA Maas; Stephan Hjorth; Robert Chamuleau; Finn Bengtsson
Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt.
Journal of neurochemistry 1995;64(3):1238-44.
1995: M H Hedberg; Anette M Johansson; Gunnar Nordvall; A Yliniemelä; H B Li; A R Martin; Stephan Hjorth; L Unelius; S Sundell; Uli Hacksell
(R)-11-hydroxy- and (R)-11-hydroxy-10-methylaporphine: synthesis, pharmacology, and modeling of D2A and 5-HT1A receptor interactions.
Journal of medicinal chemistry 1995;38(4):647-58.
1995: S B Auerbach; J F Lundberg; Stephan Hjorth
Differential inhibition of serotonin release by 5-HT and NA reuptake blockers after systemic administration.
Neuropharmacology 1995;34(1):89-96.
1994: Stephan Hjorth; S B Auerbach
Further evidence for the importance of 5-HT1A autoreceptors in the action of selective serotonin reuptake inhibitors.
European journal of pharmacology 1994;260(2-3):251-5.
1994: A McRae; E A Ling; Stephan Hjorth; Annica Dahlström; D Mason; T Tice
Catecholamine-containing biodegradable microsphere implants as a novel approach in the treatment of CNS neurodegenerative disease. A review of experimental studies in DA-lesioned rats.
Molecular neurobiology 1994;9(1-3):191-205.
1994: Stephan Hjorth; S B Auerbach
Lack of 5-HT1A autoreceptor desensitization following chronic citalopram treatment, as determined by in vivo microdialysis.
Neuropharmacology 1994;33(3-4):331-4.
1994: P Hoffmann; M Elam; P Thorén; Stephan Hjorth
Effects of long-lasting voluntary running on the cerebral levels of dopamine, serotonin and their metabolites in the spontaneously hypertensive rat.
Life sciences 1994;54(13):855-61.
1993: T Sharp; R McQuade; S Bramwell; Stephan Hjorth
Effect of acute and repeated administration of 5-HT1A receptor agonists on 5-HT release in rat brain in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 1993;348(4):339-46.
1993: matthew galloway; C S Suchowski; M J Keegan; Stephan Hjorth
Local infusion of the selective 5HT-1b agonist CP-93,129 facilitates striatal dopamine release in vivo.
Synapse (New York, N.Y.) 1993;15(1):90-2.
1993: Bo Söderpalm; B Samuel Lundin; Stephan Hjorth
Sustained 5-hydroxytryptamine release-inhibitory and anxiolytic-like action of the partial 5-HT1A receptor agonist, buspirone, after prolonged chronic administration.
European journal of pharmacology 1993;239(1-3):69-73.
1993: Stephan Hjorth; G Pettersson
5-HT1A autoreceptor-mediated effects of the amperozide congeners, FG5865 and FG5893, on rat brain 5-hydroxytryptamine neurochemistry in vivo.
European journal of pharmacology 1993;238(2-3):357-67.
1993: Stephan Hjorth; T Sharp
In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol.
The Journal of pharmacology and experimental therapeutics 1993;265(2):707-12.
1993: Stephan Hjorth
Serotonin 5-HT1A autoreceptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: a microdialysis study.
Journal of neurochemistry 1993;60(2):776-9.
1993: B B Höök; Anette M Johansson; Stephan Hjorth; S Sundell; Uli Hacksell
Synthesis of (+)-(R)- and (-)-(S)-5-hydroxy-2-methyl-2-dipropylaminotetralin: effects on rat hippocampal output of 5-HT, 5-HIAA, and DOPAC as determined by in vivo microdialysis.
Chirality 1993;5(3):112-9.
1992: Stephan Hjorth
(-)-Penbutolol as a blocker of central 5-HT1A receptor-mediated responses.
European journal of pharmacology 1992;222(1):121-7.
1992: R Tao; Stephan Hjorth
Differences in the in vitro and in vivo 5-hydroxytryptamine extraction performance among three common microdialysis membranes.
Journal of neurochemistry 1992;59(5):1778-85.
1992: Hans Nissbrandt; Nicholas Waters; Stephan Hjorth
The influence of serotoninergic drugs on dopaminergic neurotransmission in rat substantia nigra, striatum and limbic forebrain in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 1992;346(1):12-9.
1992: Stephan Hjorth
Acute reserpine treatment increases rat brain serotonin synthesis via a nerve impulse-dependent mechanism.
Journal of neurochemistry 1992;58(2):772-5.
1992: A McRae; Stephan Hjorth; Annica Dahlström; L Dillon; D Mason; T Tice
Dopamine fiber growth induction by implantation of synthetic dopamine-containing microspheres in rats with experimental hemi-parkinsonism.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1992;16(1-2):123-41.
1992: R Tao; Stephan Hjorth
Alpha 2-adrenoceptor modulation of rat ventral hippocampal 5-hydroxytryptamine release in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 1992;345(2):137-43.
1992: Hans Nissbrandt; Stephan Hjorth
Dopaminergic neurotransmission in somatodendritic and terminal areas of the rat brain: susceptibility to modulation by D1 and D2 receptors and to axotomy.
Journal of neural transmission. General section 1992;90(1):13-26.
1991: S Ahlenius; V Hillegaart; Stephan Hjorth; K Larsson
Effects of sexual interactions on the in vivo rate of monoamine synthesis in forebrain regions of the male rat.
Behavioural brain research 1991;46(2):117-22.
1991: Stephan Hjorth; R Tao
The putative 5-HT1B receptor agonist CP-93,129 suppresses rat hippocampal 5-HT release in vivo: comparison with RU 24969.
European journal of pharmacology 1991;209(3):249-52.
1991: Stephan Hjorth
Single-dose 8-OH-DPAT pretreatment does not induce tachyphylaxis to the 5-HT release-reducing effect of 5-HT1A autoreceptor agonists.
European journal of pharmacology 1991;199(2):237-42.
1991: Stephan Hjorth; T Sharp
Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis.
Life sciences 1991;48(18):1779-86.
1991: A McRae; Stephan Hjorth; D W Mason; L Dillon; T R Tice
Microencapsulated dopamine (DA)-induced restitution of function in 6-OHDA-denervated rat striatum in vivo: comparison between two microsphere excipients.
Journal of neural transplantation & plasticity 1991;2(3-4):165-73.
1990: S E Gartside; P J Cowen; Stephan Hjorth
Effects of MDL 73005EF on central pre- and postsynaptic 5-HT1A receptor function in the rat in vivo.
European journal of pharmacology 1990;191(3):391-400.
1990: Trevor Sharp; Stephan Hjorth
Application of brain microdialysis to study the pharmacology of the 5-HT1A autoreceptor.
Journal of neuroscience methods 1990;34(1-3):83-90.
1990: Stephan Hjorth; T Sharp; Y Liu
cis-(+)-8-OH-1-CH3-DPAT, (+)ALK-3, a novel stereoselective pharmacological probe for characterizing 5-HT release-controlling 5-HT1A autoreceptors. An in vivo brain microdialysis study.
Naunyn-Schmiedeberg's archives of pharmacology 1990;341(3):149-57.
1990: T Sharp; L I Backus; Stephan Hjorth; S R Bramwell; D G Grahame-Smith
Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378.
European journal of pharmacology 1990;176(3):331-40.
1990: A McRae; Stephan Hjorth; D Mason; L Dillon; T Tice
Implantable microencapsulated dopamine (DA): prolonged functional release of DA in denervated striatal tissue.
Journal of neural transmission. Supplementum 1990;29():207-15.
1990: Stephan Hjorth; T Sharp
Mixed agonist/antagonist properties of NAN-190 at 5-HT1A receptors: behavioural and in vivo brain microdialysis studies.
Life sciences 1990;46(13):955-63.
1990: V Hillegaart; Stephan Hjorth; S Ahlenius
Effects of 5-HT and 8-OH-DPAT on forebrain monoamine synthesis after local application into the median and dorsal raphe nuclei of the rat.
Journal of neural transmission. General section 1990;81(2):131-45.
1989: Stephan Hjorth; T Sharp; U Hacksell
Partial postsynaptic 5-HT1A agonist properties of the novel stereoselective 8-OH-DPAT analogue (+)cis-8-hydroxy-1-methyl-2-(di-n-propylamino)tetralin, (+)ALK-3.
European journal of pharmacology 1989;170(3):269-74.
1989: Trevor Sharp; S R Bramwell; Stephan Hjorth; DG Grahame-Smith
Pharmacological characterization of 8-OH-DPAT-induced inhibition of rat hippocampal 5-HT release in vivo as measured by microdialysis.
British journal of pharmacology 1989;98(3):989-97.
1989: Hans Nissbrandt; E Sundström; G Jonsson; Stephan Hjorth; Arvid Carlsson
Synthesis and release of dopamine in rat brain: comparison between substantia nigra pars compacts, pars reticulata, and striatum.
Journal of neurochemistry 1989;52(4):1170-82.
1989: V Hillegaart; Stephan Hjorth
Median raphe, but not dorsal raphe, application of the 5-HT1A agonist 8-OH-DPAT stimulates rat motor activity.
European journal of pharmacology 1989;160(2):303-7.
1989: Bo Söderpalm; Stephan Hjorth; Jörgen A Engel
Effects of 5-HT1A receptor agonists and L-5-HTP in Montgomery's conflict test.
Pharmacology, biochemistry, and behavior 1989;32(1):259-65.
1988: Stephan Hjorth; T Magnusson
The 5-HT 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 1988;338(5):463-71.
1988: A McRae-Degueurce; Stephan Hjorth; D L Dillon; D W Mason; T R Tice
Implantable microencapsulated dopamine (DA): a new approach for slow-release DA delivery into brain tissue.
Neuroscience letters 1988;92(3):303-9.
1988: Stephan Hjorth; D Clark; Arvid Carlsson
Dopamine (DA) autoreceptor efficacy of 3-PPP enantiomers after short-term synaptic DA deprivation.
European journal of pharmacology 1988;152(3):207-15.
1988: Francis J White; L M Bednarz; S R Wachtel; Stephan Hjorth; R J Brooderson
Is stimulation of both D1 and D2 receptors necessary for the expression of dopamine-mediated behaviors?
Pharmacology, biochemistry, and behavior 1988;30(1):189-93.
1988: L E Arvidsson; Anette M Johansson; Uli Hacksell; J Lars G Nilsson; K Svensson; Stephan Hjorth; T Magnusson; Arvid Carlsson; P Lindberg; B Andersson
N,N-Dialkylated monophenolic trans-2-phenylcyclopropylamines: novel central 5-hydroxytryptamine receptor agonists.
Journal of medicinal chemistry 1988;31(1):92-9.
1988: M Hajos; Stephan Hjorth; K Svensson; Arvid Carlsson
In vivo dopamine (DA) receptor binding and behavioural effects of the putative DA autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 in rats with a unilateral nigral 6-OH-DA lesion.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1988;70(3):577-84.
1988: Stephan Hjorth; Arvid Carlsson
In vivo receptor binding, neurochemical and functional studies with the dopamine D-1 receptor antagonist SCH23390.
Journal of neural transmission 1988;72(2):83-97.
1987: S Ahlenius; Arvid Carlsson; V Hillegaart; Stephan Hjorth; K Larsson
Region-selective activation of brain monoamine synthesis by sexual activity in the male rat.
European journal of pharmacology 1987;144(1):77-82.
1987: L E Arvidsson; Anette M Johansson; Uli Hacksell; J Lars G Nilsson; K Svensson; Stephan Hjorth; T Magnusson; Arvid Carlsson; B Andersson; H Wikström
(+)-cis-8-Hydroxy-1-methyl-2-(di-n-propylamino)tetralin: a potent and highly stereoselective 5-hydroxytryptamine receptor agonist.
Journal of medicinal chemistry 1987;30(11):2105-9.
1987: Anette M Johansson; J Lars G Nilsson; Anders Karlén; Uli Hacksell; D Sanchez; K Svensson; Stephan Hjorth; Arvid Carlsson; S Sundell; L Kenne
C1- and C3-methyl-substituted derivatives of 7-hydroxy-2-(di-n-propylamino)tetralin: activities at central dopamine receptors.
Journal of medicinal chemistry 1987;30(10):1827-37.
1987: A Fernández-Guasti; S Ahlenius; Stephan Hjorth; K Larsson
Separation of dopaminergic and serotonergic inhibitory mechanisms in the mediation of estrogen-induced lordosis behaviour in the rat.
Pharmacology, biochemistry, and behavior 1987;27(1):93-8.
1987: M Hajós; Stephan Hjorth; Arvid Carlsson
Injection of capsaicin into the nucleus raphe dorsalis elicits heat loss in the rat.
Neuroscience letters 1987;75(2):199-204.
1987: Stephan Hjorth; Arvid Carlsson; J A Engel
Anxiolytic-like action of the 3-PPP enantiomers in the Vogel conflict paradigm.
Psychopharmacology 1987;92(3):371-5.
1987: Stephan Hjorth; Arvid Carlsson
Postsynaptic dopamine (DA) receptor stimulator properties of the putative DA autoreceptor-selective agonist B-HT 920 uncovered by co-treatment with the D-1 agonist SK&F 38393.
Psychopharmacology 1987;93(4):534-7.
1987: Stephan Hjorth; Bo Söderpalm; Jörgen A Engel
Biphasic effect of L-5-HTP in the Vogel conflict model.
Psychopharmacology 1987;92(1):96-9.
1986: K Svensson; Maria L Carlsson; Arvid Carlsson; Stephan Hjorth; A M Johansson; E Eriksson
The putatively selective dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 stimulate prolactin release in rats.
European journal of pharmacology 1986;130(3):237-42.
1986: Stephan Hjorth; Arvid Carlsson
Is pindolol a mixed agonist-antagonist at central serotonin (5-HT) receptors?
European journal of pharmacology 1986;129(1-2):131-8.
1986: Stephan Hjorth; K Svensson; Arvid Carlsson; H Wikström; B Andersson
Central dopaminergic properties of HW-165 and its enantiomers; trans-octahydrobenzo(f)quinoline congeners of 3-PPP.
Naunyn-Schmiedeberg's archives of pharmacology 1986;333(3):205-18.
1986: Stephan Hjorth; E Eriksson; B Andersson
Stereoselective inhibition of prolactin secretion by (-)-HW-165, a novel 3-PPP congener; further support for similarities between central DA autoreceptors and pituitary lactotroph DA receptors.
European journal of pharmacology 1986;125(3):421-8.
1986: S Ahlenius; A Fernandez-Guasti; Stephan Hjorth; K Larsson
Suppression of lordosis behavior by the putative 5-HT receptor agonist 8-OH-DPAT in the rat.
European journal of pharmacology 1986;124(3):361-3.
1986: Stephan Hjorth; J A Engel; Arvid Carlsson
Anticonflict effects of low doses of the dopamine agonist apomorphine in the rat.
Pharmacology, biochemistry, and behavior 1986;24(2):237-40.
1986: Uli Hacksell; L E Arvidsson; Anette M Johansson; J Lars G Nilsson; D Sanchez; P Lindberg; H Wikström; K Svensson; Stephan Hjorth; Arvid Carlsson
Indirect central 5-hydroxytryptaminergic actions of methoxy substituted 2-aminotetralin derivatives.
Acta pharmaceutica Suecica 1986;23(2):77-90.
1986: K Svensson; Stephan Hjorth; D Clark; Arvid Carlsson; H Wikström; B Andersson; D Sanchez; Anette M Johansson; L E Arvidsson; U Hacksell
(+)-UH 232 and (+)-UH 242: novel stereoselective dopamine receptor antagonists with preferential action on autoreceptors.
Journal of neural transmission 1986;65(1):1-27.
1985: Stephan Hjorth; Arvid Carlsson
(-)-Pindolol stereospecifically inhibits rat brain serotonin (5-HT) synthesis.
Neuropharmacology 1985;24(11):1143-6.
1985: Stephan Hjorth; D Clark; Arvid Carlsson
Lack of functional evidence for the involvement of sigma opiate receptors in the actions of the 3-PPP enantiomers on central dopaminergic systems: discrepancies between in vitro and in vivo observations.
Life sciences 1985;37(7):673-84.
1985: Anette M Johansson; L E Arvidsson; U Hacksell; J Lars G Nilsson; K Svensson; Stephan Hjorth; D Clark; Arvid Carlsson; D Sanchez; B Andersson
Novel dopamine receptor agonists and antagonists with preferential action on autoreceptors.
Journal of medicinal chemistry 1985;28(8):1049-53.
1985: K Gradin; A Pettersson; Stephan Hjorth; T Hedner; L E Arvidsson; B Persson
Cardiovascular effects in the Sprague-Dawley rat of 8-hydroxy-2(di-N-propylamino) tetralin, a selective 5-hydroxytryptamine receptor agonist.
The Journal of pharmacy and pharmacology 1985;37(4):263-5.
1985: H Wikström; B Andersson; D Sanchez; P Lindberg; L E Arvidsson; Anette M Johansson; J Lars G Nilsson; K Svensson; Stephan Hjorth; Arvid Carlsson
Resolved monophenolic 2-aminotetralins and 1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolines: structural and stereochemical considerations for centrally acting pre- and postsynaptic dopamine-receptor agonists.
Journal of medicinal chemistry 1985;28(2):215-25.
1985: Stephan Hjorth; Arvid Carlsson; D Clark; K Svensson; D Sanchez
Dopamine receptor-mediated hypothermia induced in rats by (+)-, but not by (-)-3-PPP.
European journal of pharmacology 1985;107(3):299-304.
1985: S Kafi-de St Hilaire; J Y Sovilla; Stephan Hjorth; J M Gaillard
Modifications of sleep parameters in the rat by (+)- and (-)-3-PPP.
Journal of neural transmission 1985;62(3-4):209-17.
1985: Stephan Hjorth; D Clark; K Svensson; Arvid Carlsson; O Thorberg
Sub-chronic administration of (-)-3-PPP and central dopamine receptor sensitivity changes.
Journal of neural transmission 1985;64(3-4):187-98.
1985: D Clark; Stephan Hjorth; Arvid Carlsson
Dopamine-receptor agonists: mechanisms underlying autoreceptor selectivity. I. Review of the evidence.
Journal of neural transmission 1985;62(1-2):1-52.
1985: Stephan Hjorth
Hypothermia in the rat induced by the potent serotoninergic agent 8-OH-DPAT.
Journal of neural transmission 1985;61(1-2):131-5.
1985: Uli Hacksell; L E Arvidsson; Anette M Johansson; J Lars G Nilsson; D Sanchez; B Andersson; P Lindberg; H Wikström; Stephan Hjorth; K Svensson
5-Hydroxy-2-methyl-2-(di-n-propylamino)tetralin: synthesis and central pharmacological effects.
Acta pharmaceutica Suecica 1985;22(2):65-74.
1985: D Clark; Stephan Hjorth; Arvid Carlsson
Dopamine receptor agonists: mechanisms underlying autoreceptor selectivity. II. Theoretical considerations.
Journal of neural transmission 1985;62(3-4):171-207.
1984: D Clark; Stephan Hjorth; Arvid Carlsson
(+)- and (-)-3-PPP exhibit different intrinsic activity at striatal dopamine autoreceptors controlling dopamine synthesis.
European journal of pharmacology 1984;106(1):185-9.
1984: J A Engel; Stephan Hjorth; K Svensson; Arvid Carlsson; S Liljequist
Anticonflict effect of the putative serotonin receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT).
European journal of pharmacology 1984;105(3-4):365-8.
1984: Stephan Hjorth; J L Neumeyer
Central monoaminergic effects of two aporphine analogues to the putative serotonin-receptor agonist, 8-hydroxy-2-di-n-propylaminotetralin.
Neuropharmacology 1984;23(10):1187-90.
1984: U Hacksell; Anette M Johansson; L Arvidsson; J Lars G Nilsson; Stephan Hjorth; Arvid Carlsson; H Wikström; D Sanchez; P Lindberg
C1-Methylated 5-hydroxy-2-(dipropylamino)tetralins: central dopamine-receptor stimulating activity.
Journal of medicinal chemistry 1984;27(8):1003-7.
1984: H Wikström; D Sanchez; P Lindberg; Uli Hacksell; L E Arvidsson; Anette M Johansson; S O Thorberg; J Lars G Nilsson; K Svensson; Stephan Hjorth
Resolved 3-(3-hydroxyphenyl)-N-n-propylpiperidine and its analogues: central dopamine receptor activity.
Journal of medicinal chemistry 1984;27(8):1030-6.
1984: L E Arvidsson; Uli Hacksell; Anette M Johansson; J Lars G Nilsson; P Lindberg; D Sanchez; H Wikström; K Svensson; Stephan Hjorth; Arvid Carlsson
8-Hydroxy-2-(alkylamino)tetralins and related compounds as central 5-hydroxytryptamine receptor agonists.
Journal of medicinal chemistry 1984;27(1):45-51.
1984: M Schorderet; Stephan Hjorth; U Hacksell
Differential effects of the enantiomers of 3-PPP on dopamine D1-receptors of isolated rabbit retina.
Journal of neural transmission 1984;59(1):1-7.
1983: Stephan Hjorth; Arvid Carlsson; D Clark; K Svensson; H Wikström; D Sanchez; P Lindberg; Uli Hacksell; L E Arvidsson; A Johansson; J Lars G Nilsson
The search for selective dopaminergic autoreceptor agonists.
Journal of neural transmission. Supplementum 1983;18():131-7.
1983: Stephan Hjorth; Arvid Carlsson; D Clark; K Svensson; H Wikström; D Sanchez; P Lindberg; Uli Hacksell; L E Arvidsson; A Johansson
Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP.
Psychopharmacology 1983;81(2):89-99.
1983: Stephan Hjorth
On the mode of action of 3-(3-hydroxyphenyl)-N-n-propylpiperidine, 3-PPP, and its enantiomers. With particular reference to dopaminergic mechanisms in the central nervous system.
Acta physiologica Scandinavica. Supplementum 1983;517():1-52.
1983: D Clark; Arvid Carlsson; Stephan Hjorth; J Engel; P Lindberg
The effect of the enantiomers of 3-PPP on conditioned avoidance responding in the rat.
Psychopharmacology 1983;81(1):14-7.
1982: Stephan Hjorth; D Jackson; Arvid Carlsson; P Lindberg
A behavioral study of the changes in the CNS of mice after subchronic treatment with the dopamine autoreceptor agonist 3-PPP.
Psychopharmacology bulletin 1982;18(4):149-52.
1982: Stephan Hjorth; Arvid Carlsson
Buspirone: effects on central monoaminergic transmission--possible relevance to animal experimental and clinical findings.
European journal of pharmacology 1982;83(3-4):299-303.
1982: D Clark; Arvid Carlsson; Stephan Hjorth; K Svensson; J Engel; D Sanchez
Is 3-PPP a potential antipsychotic agent? Evidence from animal behavioral studies.
European journal of pharmacology 1982;83(1-2):131-4.
1982: H Wikström; D Sanchez; P Lindberg; L E Arvidsson; Uli Hacksell; A Johansson; J Lars G Nilsson; Stephan Hjorth; Arvid Carlsson
Monophenolic octahydrobenzo[f]quinolines: central dopamine- and serotonin-receptor stimulating activity.
Journal of medicinal chemistry 1982;25(8):925-31.
1982: D Jackson; Arvid Carlsson; Stephan Hjorth; P Lindberg
A behavioural study of the changes in the central nervous system of mice after subchronic treatment with the selective dopamine autoreceptor agonist 3-PPP (dl-3-[3-hydroxyphenyl]-N-n-propylpiperidine).
Journal of neural transmission 1982;53(4):233-45.
1981: Uli Hacksell; L E Arvidsson; U Svensson; J Lars G Nilsson; D Sanchez; H Wikström; P Lindberg; Stephan Hjorth; Arvid Carlsson
3-Phenylpiperidines. Central dopamine-autoreceptor stimulating activity.
Journal of medicinal chemistry 1981;24(12):1475-82.
1981: S Ahlenius; K Larsson; L Svensson; Stephan Hjorth; Arvid Carlsson; P Lindberg; H Wikström; D Sanchez; L E Arvidsson; Uli Hacksell; J Lars G Nilsson
Effects of a new type of 5-HT receptor agonist on male rat sexual behavior.
Pharmacology, biochemistry, and behavior 1981;15(5):785-92.
1981: L E Arvidsson; Uli Hacksell; J Lars G Nilsson; Stephan Hjorth; Arvid Carlsson; P Lindberg; D Sanchez; H Wikstrom
8-Hydroxy-2-(di-n-propylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist.
Journal of medicinal chemistry 1981;24(8):921-3.
1981: Uli Hacksell; L E Arvidsson; U Svensson; J Lars G Nilsson; H Wikström; P Lindberg; D Sanchez; Stephan Hjorth; Arvid Carlsson; L Paalzow
Monophenolic 2-(dipropylamino)indans and related compounds: central dopamine-receptor stimulating activity.
Journal of medicinal chemistry 1981;24(4):429-34.
1981: Stephan Hjorth; Arvid Carlsson; H Wikström; P Lindberg; D Sanchez; Uli Hacksell; L E Arvidsson; U Svensson; J Lars G Nilsson
3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors.
Life sciences 1981;28(11):1225-38.
1980: Stephan Hjorth; Arvid Carlsson; P Lindberg
A new centrally acting DA-receptor agonist with selectivity for autoreceptors.
Psychopharmacology bulletin 1980;16(3):85-90.
1979: U Hacksell; U Svensson; J L Nilsson; Stephan Hjorth; Arvid Carlsson; H Wikström; P Lindenberg; D Sanchez
N-Alkylated 2-aminotetralins: central dopamine-receptor stimulating activity.
Journal of medicinal chemistry 1979;22(12):1469-75.
1978: H Wikström; P Lindberg; P Martinson; Stephan Hjorth; Arvid Carlsson
Pivaloyl esters of N,N-dialkylated dopamine congeners. Central dopamine-receptor stimulating activity.
Journal of medicinal chemistry 1978;21(9):864-7.