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Amanda Myers

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Margarita Giraldo; Julian Carvajal; Richard J Caselli; Jason J Corneveaux; Christopher Gaiteri; Kenneth S Kosik; Francisco Lopera; Claudia Muñoz; Amanda Myers; Manuel Ramirez-Restrepo; Eric M Reiman; Isabelle Schrauwen; Ashley L Siniard; Matthew Huentelman
Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease.
Andrew S P Lim; Amanda Myers; Lei Yu; Aron S Buchman; Philip L De Jager; Jeanne F Duffy; David A Bennett
Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
Patrick Holton; Matthew J Huentelman; Richard Mayeux; Amanda Myers; Michael Nalls; Margaret A Pericak-Vance; Manuel Ramirez-Restrepo; Eric M Reiman; Mina Ryten; Gerard D Schellenberg; Andrew Singleton; Daniah Trabzuni; Michael E Weale; Liana G Apostolova; Steven E Arnold; Clinton T Baldwin; Robert Barber; Michael M Barmada; Thomas G Beach; Gary W Beecham; Duane Beekly; David A Bennett; Eileen H Bigio; Thomas D Bird; Deborah Blacker; Bradley F Boeve; James D Bowen; Adam Boxer; James R Burke; Jacqueline Buros; Joseph D Buxbaum; Nigel J Cairns; Laura B Cantwell; Chuanhai Cao; Chris S Carlson; Regina M Carney; Minerva M Carrasquillo; Steven L Carroll; Helena C Chui; David G Clark; Carl W Cotman; Paul K Crane; Elizabeth A Crocco; Carlos Cruchaga; Jeffrey L Cummings; Philip L De Jager; Charles DeCarli; Steven T DeKosky; F Yesim Demirci; Ramon Diaz-Arrastia; Malcolm Dick; Dennis W Dickson; Ranjan Duara; William G Ellis; Nilufer Ertekin-Taner; Denis Evans; Kelley M Faber; Kenneth B Fallon; Martin R Farlow; Steven Ferris; Tatiana M Foroud; Matthew P Frosch; Douglas R Galasko; Mary Ganguli; Marla Gearing; Daniel H Geschwind; Bernardino Ghetti; John R Gilbert; Sid Gilman; Bruno Giordani; Jonathan D Glass; Alison M Goate; Neill R Graff-Radford; Robert C Green; John H Growdon; Hakon Hakonarson; Ronald L Hamilton; Lindy E Harrell; Elizabeth Head; Lawrence S Honig; Christine M Hulette; Bradley T Hyman; Gail P Jarvik; Gregory A Jicha; Lee-Way Jin; Gyungah Jun; M Ilyas Kamboh; Jason Karlawish; Anna Karydas; John S K Kauwe; Jeffrey A Kaye; Ronald Kim; Edward H Koo; Neil W Kowall; Patricia Kramer; Walter A Kukull; James J Lah; Eric B Larson; Allan I Levey; Andrew P Lieberman; Oscar L Lopez; Kathryn L Lunetta; Wendy J Mack; Daniel C Marson; Eden R Martin; Frank Martiniuk; Deborah C Mash; Eliezer Masliah; Wayne C McCormick; Susan M McCurry; Andrew N McDavid; Ann C McKee; Marsel Mesulam; Bruce L Miller; Carol A Miller; Joshua W Miller; Thomas J Montine; John C Morris; Adam C Naj; Petra Nowotny; Joseph E Parisi; Elaine Peskind; Ronald C Petersen; Wayne W Poon; Huntington Potter; Joseph F Quinn; Ashok Raj; Ruchita A Rajbhandary; Murray Raskind; Barry Reisberg; Christiane Reitz; John M Ringman; Erik D Roberson; Ekaterina Rogaeva; Roger N Rosenberg; Mary Sano; Andrew J Saykin; Julie A Schneider; Lon S Schneider; William W Seeley; Michael L Shelanski; Charles D Smith; Joshua A Sonnen; Salvatore Spina; Peter St George-Hyslop; Robert A Stern; Rudolph E Tanzi; John Q Trojanowski; Juan C Troncoso; Debby W Tsuang; Otto Valladares; Vivianna M Van Deerlin; Badri N Vardarajan; Harry V Vinters; Jean Paul Vonsattel; Li-San Wang; Sandra Weintraub; Kathleen A Welsh-Bohmer; Jennifer Williamson; Randall L Woltjer; Clinton B Wright; Mark R Cookson; Jason J Corneveaux; Helen Crehan; Allissa Dillman; Anzhelika Engel; Lindsay Farrer; J Raphael Gibbs; Rita Guerreiro; Jonathan L Haines; John Hardy; Dena Hernandez; Steven G Younkin
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.

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2013: Margarita Giraldo; Julian Carvajal; Richard J Caselli; Jason J Corneveaux; Christopher Gaiteri; Kenneth S Kosik; Francisco Lopera; Claudia Muñoz; Amanda Myers; Manuel Ramirez-Restrepo; Eric M Reiman; Isabelle Schrauwen; Ashley L Siniard; Matthew Huentelman
Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease.
Neurobiology of aging 2013;34(8):2077.e11-8.
2013: Andrew S P Lim; Amanda Myers; Lei Yu; Aron S Buchman; Philip L De Jager; Jeanne F Duffy; David A Bennett
Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
Journal of biological rhythms 2013;28(2):117-29.
2013: Patrick Holton; Matthew J Huentelman; Richard Mayeux; Amanda Myers; Michael Nalls; Margaret A Pericak-Vance; Manuel Ramirez-Restrepo; Eric M Reiman; Mina Ryten; Gerard D Schellenberg; Andrew Singleton; Daniah Trabzuni; Michael E Weale; Liana G Apostolova; Steven E Arnold; Clinton T Baldwin; Robert Barber; Michael M Barmada; Thomas G Beach; Gary W Beecham; Duane Beekly; David A Bennett; Eileen H Bigio; Thomas D Bird; Deborah Blacker; Bradley F Boeve; James D Bowen; Adam Boxer; James R Burke; Jacqueline Buros; Joseph D Buxbaum; Nigel J Cairns; Laura B Cantwell; Chuanhai Cao; Chris S Carlson; Regina M Carney; Minerva M Carrasquillo; Steven L Carroll; Helena C Chui; David G Clark; Carl W Cotman; Paul K Crane; Elizabeth A Crocco; Carlos Cruchaga; Jeffrey L Cummings; Philip L De Jager; Charles DeCarli; Steven T DeKosky; F Yesim Demirci; Ramon Diaz-Arrastia; Malcolm Dick; Dennis W Dickson; Ranjan Duara; William G Ellis; Nilufer Ertekin-Taner; Denis Evans; Kelley M Faber; Kenneth B Fallon; Martin R Farlow; Steven Ferris; Tatiana M Foroud; Matthew P Frosch; Douglas R Galasko; Mary Ganguli; Marla Gearing; Daniel H Geschwind; Bernardino Ghetti; John R Gilbert; Sid Gilman; Bruno Giordani; Jonathan D Glass; Alison M Goate; Neill R Graff-Radford; Robert C Green; John H Growdon; Hakon Hakonarson; Ronald L Hamilton; Lindy E Harrell; Elizabeth Head; Lawrence S Honig; Christine M Hulette; Bradley T Hyman; Gail P Jarvik; Gregory A Jicha; Lee-Way Jin; Gyungah Jun; M Ilyas Kamboh; Jason Karlawish; Anna Karydas; John S K Kauwe; Jeffrey A Kaye; Ronald Kim; Edward H Koo; Neil W Kowall; Patricia Kramer; Walter A Kukull; James J Lah; Eric B Larson; Allan I Levey; Andrew P Lieberman; Oscar L Lopez; Kathryn L Lunetta; Wendy J Mack; Daniel C Marson; Eden R Martin; Frank Martiniuk; Deborah C Mash; Eliezer Masliah; Wayne C McCormick; Susan M McCurry; Andrew N McDavid; Ann C McKee; Marsel Mesulam; Bruce L Miller; Carol A Miller; Joshua W Miller; Thomas J Montine; John C Morris; Adam C Naj; Petra Nowotny; Joseph E Parisi; Elaine Peskind; Ronald C Petersen; Wayne W Poon; Huntington Potter; Joseph F Quinn; Ashok Raj; Ruchita A Rajbhandary; Murray Raskind; Barry Reisberg; Christiane Reitz; John M Ringman; Erik D Roberson; Ekaterina Rogaeva; Roger N Rosenberg; Mary Sano; Andrew J Saykin; Julie A Schneider; Lon S Schneider; William W Seeley; Michael L Shelanski; Charles D Smith; Joshua A Sonnen; Salvatore Spina; Peter St George-Hyslop; Robert A Stern; Rudolph E Tanzi; John Q Trojanowski; Juan C Troncoso; Debby W Tsuang; Otto Valladares; Vivianna M Van Deerlin; Badri N Vardarajan; Harry V Vinters; Jean Paul Vonsattel; Li-San Wang; Sandra Weintraub; Kathleen A Welsh-Bohmer; Jennifer Williamson; Randall L Woltjer; Clinton B Wright; Mark R Cookson; Jason J Corneveaux; Helen Crehan; Allissa Dillman; Anzhelika Engel; Lindsay Farrer; J Raphael Gibbs; Rita Guerreiro; Jonathan L Haines; John Hardy; Dena Hernandez; Steven G Younkin
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.
Annals of human genetics 2013;77(2):85-105.
2012: Andrew S P Lim; Amanda Myers; Towfique Raj; Katherine Rothamel; Clifford B Saper; Joshua M Shulman; Jeanne F Duffy; David A Bennett; Christophe Benoist; Aron S Buchman; Sean W Cain; Anne-Marie Chang; Lori B Chibnik; Charles A Czeisler; Philip L De Jager
A common polymorphism near PER1 and the timing of human behavioral rhythms.
Annals of neurology 2012;72(3):324-34.
2012: Amanda Myers; Charles Nemeroff
APOE: a risk factor for multiple disorders.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2012;20(7):545-8.
2012: Amanda Myers
The age of the "ome": genome, transcriptome and proteome data set collection and analysis.
Brain research bulletin 2012;88(4):294-301.
2012: Brendan T Keenan; Cynthia A Lemere; Amanda Myers; Anne Nicholson-Weller; Towfique Raj; Eric M Reiman; Mert R Sabuncu; Joshua M Shulman; Dong Tran; April N Allen; David A Bennett; Lori B Chibnik; Jason J Corneveaux; Denis A Evans; John A Hardy; Matthew Huentelman; Philip L De Jager
A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline.
Human molecular genetics 2012;21(10):2377-88.
2012: Philip L De Jager; Christopher D Anderson; Cristin Aubin; David A Bennett; Alessandro Biffi; Lori B Chibnik; Jason J Corneveaux; Mark J Daly; Matthew Huentelman; Brendan T Keenan; Sue E Leurgans; Amanda Myers; Towfique Raj; Eric M Reiman; Jonathan Rosand; Joshua M Shulman; Dong Tran; Robert S Wilson; Lei Yu; Denis A Evans
A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
Neurobiology of aging 2012;33(5):1017.e1-15.
2012: Shanker Swaminathan; Mari Turk; Jason Corneveaux; Kelley M Faber; Tatiana Foroud; John Hardy; Matthew Huentelman; Sungeun Kim; Richard Mayeux; Amanda Myers; Eric M Reiman; Andrew J. Saykin; Li Shen
Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
PloS one 2012;7(12):e50640.
2011: Adam C Naj; Gyungah Jun; Gary Beecham; Li-San Wang; Badri Narayan Vardarajan; Jacqueline Buros; Paul J Gallins; Joseph Buxbaum; Gail P Jarvik; Paul K Crane; Eric B Larson; Thomas D Bird; Bradley F Boeve; Neill R Graff-Radford; Philip L De Jager; Denis Evans; Julie A Schneider; Minerva M Carrasquillo; Nilufer Ertekin-Taner; Steven G Younkin; Carlos Cruchaga; John S K Kauwe; Petra Nowotny; Patricia Kramer; John Hardy; Matthew Huentelman; Amanda Myers; M. Michael Barmada; F Yesim Demirci; Clinton T Baldwin; Robert C Green; Ekaterina Rogaeva; Steven E Arnold; Robert C Barber; Thomas Beach; Eileen H Bigio; James D Bowen; Adam Boxer; James R Burke; Nigel J Cairns; Chris S Carlson; Regina M Carney; Steven L Carroll; Helena C Chui; David G Clark; Jason Corneveaux; Carl W Cotman; Jeffrey L Cummings; Charles DeCarli; Steven T DeKosky; Ramon Diaz-Arrastia; Malcolm Dick; dennis dickson; William G Ellis; Kelley M Faber; Kenneth B Fallon; Martin R Farlow; Steven Ferris; Matthew P Frosch; Douglas Galasko; Mary Ganguli; Marla Gearing; Daniel Geschwind; Bernardino Ghetti; John Gilbert; Sid Gilman; Bruno Giordani; Jonathan D Glass; John H Growdon; Ronald L Hamilton; Lindy E Harrell; Elizabeth Head; Lawrence Honig; Christine M Hulette; Bradley T Hyman; Gregory A Jicha; Lee-Way Jin; Nancy Johnson; Jason Karlawish; Anna Karydas; Jeffrey A Kaye; Ronald Kim; Edward H Koo; Neil W Kowall; James J Lah; Allan Levey; Andrew P Lieberman; Oscar L Lopez; Wendy J Mack; Daniel C Marson; Frank Martiniuk; Deborah C Mash; Eliezer Masliah; Wayne C McCormick; Susan M McCurry; Andrew N McDavid; Ann C McKee; Marsel Mesulam; Bruce L Miller; Carol A Miller; Joshua Miller; Joseph E Parisi; Daniel P Perl; Elaine Peskind; Ronald C. Petersen; Wayne W Poon; Joseph F Quinn; Ruchita A Rajbhandary; Murray Raskind; Barry Reisberg; John M Ringman; Erik D Roberson; Roger N Rosenberg; Mary Sano; Lon S Schneider; William Seeley; Michael L Shelanski; Michael Slifer; Charles D Smith; Joshua A Sonnen; Salvatore Spina; Robert A Stern; Rudolph E Tanzi; John Q Trojanowski; Juan C Troncoso; Vivianna M Van Deerlin; Harry V Vinters; Jean Paul Vonsattel; Sandra Weintraub; Kathleen A Welsh-Bohmer; Jennifer Williamson; Randall L Woltjer; Laura B Cantwell; Beth A Dombroski; Duane Beekly; Kathryn L Lunetta; Eden R Martin; M Ilyas Kamboh; Andrew J Saykin; Eric Reiman; David A Bennett; John C Morris; Thomas J Montine; Alison Goate; Deborah Blacker; Debby W Tsuang; Hakon Hakonarson; Walter A Kukull; Tatiana M Foroud; Jonathan L Haines; Richard Mayeux; Margaret Pericak-Vance; Lindsay Farrer; Peter St George-Hyslop; Gerard D Schellenberg
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Nature genetics 2011;43(5):436-41.
2011: Lori B Chibnik; Joshua M Shulman; Sue E Leurgans; Julie A Schneider; Robert S Wilson; Dong Tran; Cristin Aubin; Aron S Buchman; Christopher B Heward; Amanda Myers; John Hardy; Matthew Huentelman; Jason J Corneveaux; Eric Reiman; Denis A Evans; David A Bennett; Philip De Jager
CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Annals of neurology 2011;69(3):560-9.
2011: Kerry J Ressler; Kristina B Mercer; Bekh Bradley; Tanja Jovanovic; Amy Mahan; Kimberly Kerley; Seth D Norrholm; Varun Kilaru; Alicia K Smith; Amanda Myers; Manuel Ramirez; Anzhelika Engel; Sayamwong E Hammack; Donna J Toufexis; Karen M Braas; Elisabeth B Binder; Victor May
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor.
Nature 2011;470(7335):492-7.
2011: Winnie S Liang; Kewei Chen; Wendy Lee; Kunal Sidhar; Jason J Corneveaux; April N Allen; Amanda Myers; Stephen Villa; Bessie Meechoovet; Jeremy Pruzin; Daniel Bandy; Adam S Fleisher; Jessica B S Langbaum; Matthew Huentelman; Kendall Jensen; Travis Dunkley; Richard Caselli; Susan Kaib; Eric Reiman
Association between GAB2 haplotype and higher glucose metabolism in Alzheimer's disease-affected brain regions in cognitively normal APOEε4 carriers.
NeuroImage 2011;54(3):1896-902.
2010: Jason J Corneveaux; Amanda Myers; April N Allen; Jeremy J Pruzin; Manuel Ramirez; Anzhelika Engel; Michael A Nalls; Kewei Chen; Wendy Lee; Kendria Chewning; Stephen E Villa; Hunsar B Meechoovet; Jill D Gerber; Danielle Frost; Hollie L Benson; Sean O'Reilly; Lori B Chibnik; Joshua M Shulman; Andrew Singleton; David Craig; Kendall R Van Keuren-Jensen; Travis Dunckley; David A Bennett; Philip L De Jager; Christopher Heward; John Hardy; Eric Reiman; Matthew Huentelman
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Human molecular genetics 2010;19(16):3295-301.
2010: Jason J Corneveaux; Winnie S Liang; Eric Reiman; Jennifer A Webster; Amanda Myers; Victoria L Zismann; Keta D Joshipura; John Pearson; Diane Hu-Lince; David Craig; Keith D Coon; Travis Dunckley; Daniel Bandy; Wendy Lee; Kewei Chen; Thomas Beach; Diego Mastroeni; Andrew Grover; Rivka Ravid; Sigrid B Sando; Jan O Aasly; Reinhard Heun; Frank Jessen; Heike Kölsch; Joseph Rogers; Michael Hutton; Stacey Melquist; Ronald C. Petersen; Gene Alexander; Richard Caselli; Andreas Papassotiropoulos; Dietrich A Stephan; Matthew Huentelman
Evidence for an association between KIBRA and late-onset Alzheimer's disease.
Neurobiology of aging 2010;31(6):901-9.
2010: Jennifer Webster; Eric Reiman; Victoria L Zismann; Keta D Joshipura; John Pearson; Diane Hu-Lince; Matthew J Huentelman; David Craig; Keith D Coon; Thomas Beach; Kristen C Rohrer; Alice S Zhao; Doris Leung; Leslie Bryden; Lauren Marlowe; Mona Kaleem; Diego Mastroeni; Andrew Grover; Joseph Rogers; Reinhard Heun; Frank Jessen; Heike Kölsch; Christopher B Heward; Rivka Ravid; Michael Hutton; Stacey Melquist; Ronald C. Petersen; Richard Caselli; Andreas Papassotiropoulos; Dietrich A Stephan; John Hardy; Amanda Myers
Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis.
International journal of molecular epidemiology and genetics 2010;1(1):19-30.
2009: Jennifer A Webster; J Raphael Gibbs; Jennifer Clarke; Monika Ray; Weixiong Zhang; Peter Holmans; Kristen Rohrer; Alice Zhao; Lauren Marlowe; Mona Kaleem; Donald S McCorquodale; Cindy Cuello; Doris Leung; Leslie Bryden; Priti Nath; Victoria L Zismann; Keta Joshipura; Matthew Huentelman; Diane Hu-Lince; Keith D Coon; David Craig; John Pearson; Christopher B Heward; Eric Reiman; Dietrich A Stephan; John Hardy; Amanda Myers
Genetic control of human brain transcript expression in Alzheimer disease.
American journal of human genetics 2009;84(4):445-58.
2008: Marcel van der Brug; Jeff Blackinton; Jayanth Chandran; Ling-Yang Hao; Ashish Lal; Krystyna Mazan-Mamczarz; Jennifer L Martindale; Chengsong Xie; Rili Ahmad; Kelly J Thomas; Alexandra Beilina; J Raphael Gibbs; Jinhui Ding; Amanda Myers; Ming Zhan; Huaibin Cai; Nancy M Bonini; Myriam Gorospe; Mark Cookson
RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):10244-9.
2008: Donald McCorquodale; Amanda Myers
Biomarkers in the diagnosis and treatment of Alzheimer's disease: potential and pitfalls.
Biomarkers in medicine 2008;2(3):209-14.
2008: Mun-Gwan Hong; Amanda Myers; Patrik K E Magnusson; Jonathan A Prince
Transcriptome-wide assessment of human brain and lymphocyte senescence.
PloS one 2008;3(8):e3024.
2008: Jennifer A Webster; Amanda Myers; John Pearson; David Craig; Diane Hu-Lince; Keith D Coon; Victoria L Zismann; Thomas Beach; Doris Leung; Leslie Bryden; Rebecca F Halperin; Lauren Marlowe; Mona Kaleem; Matthew Huentelman; Keta Joshipura; Douglas G. Walker; Christopher B Heward; Rivka Ravid; Joseph Rogers; Andreas Papassotiropoulos; John Hardy; Eric Reiman; Dietrich A Stephan
Sorl1 as an Alzheimer's disease predisposition gene?
Neuro-degenerative diseases 2008;5(2):60-4.
2007: Amanda Myers; J Raphael Gibbs; Jennifer A Webster; Kristen Rohrer; Alice Zhao; Lauren Marlowe; Mona Kaleem; Doris Leung; Leslie Bryden; Priti Nath; Victoria L Zismann; Keta Joshipura; Matthew Huentelman; Diane Hu-Lince; Keith D Coon; David Craig; John Pearson; Peter Holmans; Christopher B Heward; Eric Reiman; Dietrich A Stephan; John Hardy
A survey of genetic human cortical gene expression.
Nature genetics 2007;39(12):1494-9.
2007: Marian Hamshere; Peter Holmans; Dimitrios Avramopoulos; Susan S Bassett; Deborah Blacker; Lars Bertram; Howard Wiener; Nan Rochberg; Rudolph E Tanzi; Amanda Myers; Fabienne Wavrant-De Vrièze; Rodney Go; Daniele Fallin; Simon Lovestone; John Hardy; Alison Goate; Michael O'Donovan; Julie Williams; Michael J Owen
Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease.
Human molecular genetics 2007;16(22):2703-12.
2007: Paul Hollingworth; Marian Hamshere; Peter Holmans; Michael C O'Donovan; Rebecca Sims; John Powell; Simon Lovestone; Amanda Myers; FW DeVrieze; John Hardy; Alison Goate; Michael J Owen; Julie Williams
Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(7):841-8.
2007: Eric Reiman; Jennifer A Webster; Amanda Myers; John Hardy; Travis Dunkley; Victoria L Zismann; Keta D Joshipura; John Pearson; Diane Hu-Lince; Matthew Huentelman; David Craig; Keith D Coon; Winnie S Liang; RiLee H Herbert; Thomas Beach; Kristen C Rohrer; Alice S Zhao; Doris Leung; Leslie Bryden; Lauren Marlowe; Mona Kaleem; Diego Mastroeni; Andrew Grover; Christopher B Heward; Rivka Ravid; Joseph Rogers; Michael Hutton; Stacey Melquist; Ronald C. Petersen; Gene Alexander; Richard Caselli; Walter A Kukull; Andreas Papassotiropoulos; Dietrich A Stephan
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Neuron 2007;54(5):713-20.
2007: Giancarlo V De Ferrari; Andreas Papassotiropoulos; Travis L Biechele; Fabienne Wavrant De-Vrieze; Miguel E Avila; Michael Ben Major; Amanda Myers; Katia Sáez; Juan P Henríquez; Alice Zhao; M Axel Wollmer; Roger M Nitsch; Christoph Hock; Christopher M Morris; John Hardy; Randall T Moon
Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(22):9434-9.
2007: Keith D Coon; Amanda Myers; David Craig; Jennifer A Webster; John Pearson; Diane Hu Lince; Victoria L Zismann; Thomas Beach; Doris Leung; Leslie Bryden; Rebecca F Halperin; Lauren Marlowe; Mona Kaleem; Douglas G. Walker; Rivka Ravid; Christopher B Heward; Joseph Rogers; Andreas Papassotiropoulos; Eric Reiman; John Hardy; Dietrich A Stephan
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.
The Journal of clinical psychiatry 2007;68(4):613-8.
2007: Amanda Myers; Alan Pittman; Alice S Zhao; Kristen Rohrer; Mona Kaleem; Lauren Marlowe; Andrew J Lees; Doris Leung; Ian G McKeith; Robert H Perry; Christopher M Morris; John Q Trojanowski; Christopher Clark; Jason H T Karlawish; Steven E Arnold; Mark S Forman; Vivianna M Van Deerlin; Rohan de Silva; John Hardy
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts.
Neurobiology of disease 2007;25(3):561-70.
2007: John Hardy; Amanda Myers
Genetic variability in expression of proteins and the risk of sporadic neurologic diseases.
Neurology 2007;68(9):632-3.
2007: Mona Kaleem; A Zhao; Marian Hamshere; Amanda Myers
Identification of a novel valosin-containing protein polymorphism in late-onset Alzheimer's disease.
Neuro-degenerative diseases 2007;4(5):376-81.
2006: Lauren Marlowe; Rita Peila; Kelly Suzanne Benke; John Hardy; Lon R White; Lenore J Launer; Amanda Myers
Insulin-degrading enzyme haplotypes affect insulin levels but not dementia risk.
Neuro-degenerative diseases 2006;3(6):320-6.
2006: John Hardy; Alan Pittman; Amanda Myers; Hon-Chung Fung; Rohan de Silva; Jaime Duckworth
Tangle diseases and the tau haplotypes.
Alzheimer disease and associated disorders 2006;20(1):60-2.
2006: Andrew Grupe; Yonghong Li; Charles Rowland; Petra Nowotny; Anthony L Hinrichs; Scott Smemo; John S K Kauwe; Taylor J Maxwell; Sara Cherny; Lisa Doil; Kristina Tacey; Ryan van Luchene; Amanda Myers; Fabienne Wavrant-De Vrièze; Mona Kaleem; Paul Hollingworth; Luke Jehu; Catherine Foy; Nicola Archer; Gillian Hamilton; Peter Holmans; Chris M Morris; Joseph Catanese; John Sninsky; Thomas J White; John Powell; John Hardy; Michael O'Donovan; Simon Lovestone; Lesley Jones; John C Morris; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
American journal of human genetics 2006;78(1):78-88.
2006: Scott Smemo; Petra Nowotny; Anthony L Hinrichs; John S K Kauwe; Sara Cherny; Katherine Erickson; Amanda Myers; Mona Kaleem; Lauren Marlowe; Alison M Gibson; Paul Hollingworth; Michael C O'Donovan; Christopher M Morris; Peter Holmans; Simon Lovestone; John C Morris; Leon J Thal; Yonghong Li; Andrew Grupe; John Hardy; Michael J Owen; Julie Williams; Alison Goate
Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.
Annals of neurology 2006;59(1):21-6.
2005: Alan Pittman; Amanda Myers; Patrick M Abou-Sleiman; Hon-Chung Fung; Mona Kaleem; Lauren Marlowe; Jaime Duckworth; Doris Leung; D Williams; Linda Kilford; N Thomas; Christopher M Morris; dennis dickson; Nicholas W Wood; John Hardy; Andrew J Lees; Rohan de Silva
Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration.
Journal of medical genetics 2005;42(11):837-46.
2005: Amanda Myers; Mona Kaleem; Lauren Marlowe; Alan Pittman; Andrew J Lees; Hon-Chung Fung; Jaime Duckworth; Doris Leung; A Gibson; Christopher M Morris; Rohan de Silva; John Hardy
The H1c haplotype at the MAPT locus is associated with Alzheimer's disease.
Human molecular genetics 2005;14(16):2399-404.
2005: John Hardy; Alan Pittman; Amanda Myers; Katrina Gwinn-Hardy; Hon-Chung Fung; Rohan de Silva; Michael Hutton; Jaime Duckworth
Evidence suggesting that Homo neanderthalensis contributed the H2 MAPT haplotype to Homo sapiens.
Biochemical Society transactions 2005;33(Pt 4):582-5.
2005: Petra Nowotny; Anthony L Hinrichs; Scott Smemo; John S K Kauwe; Taylor Maxwell; Peter Holmans; Marian Hamshere; Darko Turic; Luke Jehu; Paul Hollingworth; Pamela Moore; Leslie Bryden; Amanda Myers; Lisa M Doil; Kristina M Tacey; Alison M Gibson; Ian G McKeith; Robert H Perry; Christopher M Morris; Leon J Thal; John C Morris; Michael C O'Donovan; Simon Lovestone; Andrew Grupe; John Hardy; Michael J Owen; Julie Williams; Alison Goate
Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;136B(1):62-8.
2005: Peter Holmans; Marian Hamshere; Paul Hollingworth; Frances Rice; Nigel Tunstall; Sue Jones; Pamela Moore; Fabienne Wavrant DeVrieze; Amanda Myers; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Michael O'Donovan; Lesley Jones; John Hardy; Alison Goate; Simon Lovestone; Michael J Owen; Julie Williams
Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;135B(1):24-32.
2005: Hon-Chung Fung; Jessica Evans; Whitney Evans; Jaime Duckworth; Alan Pittman; Rohan de Silva; Amanda Myers; John Hardy
The architecture of the tau haplotype block in different ethnicities.
Neuroscience letters 2005;377(2):81-4.
2004: Whitney Evans; Hon-Chung Fung; John Steele; Johanna Eerola; Pentti J Tienari; Alan Pittman; Rohan de Silva; Amanda Myers; Fabienne Wavrant-De Vrieze; Andrew Singleton; John Hardy
The tau H2 haplotype is almost exclusively Caucasian in origin.
Neuroscience letters 2004;369(3):183-5.
2004: Alan Pittman; Amanda Myers; Jaime Duckworth; Leslie Bryden; Melissa Hanson; Patrick M Abou-Sleiman; Nicholas W Wood; John Hardy; Andrew J Lees; Rohan de Silva
The structure of the tau haplotype in controls and in progressive supranuclear palsy.
Human molecular genetics 2004;13(12):1267-74.
2004: Andrew Singleton; Amanda Myers; John Hardy
The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases.
Human molecular genetics 2004;13 Spec No 1():R123-6.
2004: John Hardy; Amanda Myers; Fabienne Wavrant De-Vrieze
Problems and solutions in the genetic analysis of late-onset Alzheimer's disease.
Neuro-degenerative diseases 2004;1(4-5):213-7.
2004: Victoria Busby; Steven Goossens; Petra Nowotny; Gillian Hamilton; Scott Smemo; Denise Harold; Dragana Turic; Luke Jehu; Amanda Myers; Meredith Womick; Daniel Woo; Danielle Compton; Lisa M Doil; Kristina M Tacey; Kit F Lau; Safa Al-Saraj; Richard Killick; Stuart Pickering-Brown; Pamela Moore; Paul Hollingworth; Nicola Archer; Catherine Foy; Sarah Walter; Corrine Lendon; Takeshi Iwatsubo; John C Morris; Joanne Norton; D M A Mann; Barbara Janssens; John Hardy; Michael O'Donovan; Lesley Jones; Julie Williams; Peter Holmans; Michael J Owen; Andrew Grupe; John Powell; Jolanda van Hengel; Alison Goate; Frans Van Roy; Simon Lovestone
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
Neuromolecular medicine 2004;5(2):133-46.
2004: Henry C Kitchener; S Burns; Linsey Nelson; Amanda Myers; I Fletcher; M Desai; G Dunn; P Maguire
A randomised controlled trial of cytological surveillance versus patient choice between surveillance and colposcopy in managing mildly abnormal cervical smears.
BJOG : an international journal of obstetrics and gynaecology 2004;111(1):63-70.
2004: Amanda Myers; Helen Marshall; Peter Holmans; Danielle Compton; Richard Crook; adrian mander; Petra Nowotny; Scott Smemo; Melanie Dunstan; Luke Jehu; Jen C Wang; Marian Hamshere; John C Morris; Joanne Norton; Sumi Chakraventy; Nigel Tunstall; Simon Lovestone; Ronald C. Petersen; Michael O'Donovan; Lesley Jones; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;124B(1):29-37.
2003: Denise Harold; Tim Peirce; Valentina Moskvina; Amanda Myers; Susan Jones; Paul Hollingworth; Pamela Moore; Simon Lovestone; John Powell; Catherine Foy; Nicola Archer; Sarah Walter; Amanda Edmonson; Stephen McIlroy; David Craig; Peter Passmore; Alison Goate; John Hardy; Michael O'Donovan; Julie Williams; Malcolm Liddell; Michael J Owen; Lesley Jones
Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease.
Human genetics 2003;113(3):258-67.
2002: Amanda Myers; Fabienne Wavrant De-Vrieze; Peter Holmans; Marian Hamshere; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Heather Knowles; John C Morris; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Frances Rice; Peter Giles; Nigel Tunstall; Lesley Jones; Simon Lovestone; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Full genome screen for Alzheimer disease: stage II analysis.
American journal of medical genetics 2002;114(2):235-44.
2001: Richard Abraham; Amanda Myers; Fabienne Wavrant DeVrieze; Marian Hamshere; Hollie V Thomas; Helen Marshall; Danielle Compton; Gillian Spurlock; Darko Turic; Bastiaan Hoogendoorn; Jennifer M Kwon; Ronald C. Petersen; Eric G Tangalos; J Norton; John C Morris; Ross Bullock; D Liolitsa; Simon Lovestone; John Hardy; Alison Goate; Michael O'Donovan; Julie Williams; Michael J Owen; Lesley Jones
Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.
Human genetics 2001;109(6):646-52.
2001: Amanda Myers; Alison Goate
The genetics of late-onset Alzheimer's disease.
Current opinion in neurology 2001;14(4):433-40.
2000: Amanda Myers; Peter Holmans; Helen Marshall; J Kwon; David Meyer; Dzanan Ramic; Shantia Shears; Jeremy Booth; FW DeVrieze; Richard Crook; Marian Hamshere; Richard Abraham; Nigel Tunstall; Frances Rice; S Carty; S Lillystone; Pat Kehoe; Varuni Rudrasingham; Lesley Jones; Simon Lovestone; Jordi Perez-Tur; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Susceptibility locus for Alzheimer's disease on chromosome 10.
Science (New York, N.Y.) 2000;290(5500):2304-5.
1998: Jeffrey N. Joyce; Amanda Myers; EV Gurevich
Dopamine D2 receptor bands in normal human temporal cortex are absent in Alzheimer's disease.
Brain research 1998;784(1-2):7-17.
1997: Jeffrey N. Joyce; G Smutzer; C J Whitty; Amanda Myers; Michael J Bannon
Differential modification of dopamine transporter and tyrosine hydroxylase mRNAs in midbrain of subjects with Parkinson's, Alzheimer's with parkinsonism, and Alzheimer's disease.
Movement disorders : official journal of the Movement Disorder Society 1997;12(6):885-97.
1997: Corinne Lendon; Amanda Myers; Alistair Cumming; Alison Goate; David St Clair
A polymorphism in the presenilin 1 gene does not modify risk for Alzheimer's disease in a cohort with sporadic early onset.
Neuroscience letters 1997;228(3):212-4.
1997: Corinne Lendon; A Martinez; I M Behrens; Kenneth S Kosik; L Madrigal; Joanne Norton; Rosalind J Neuman; Amanda Myers; F Busfield; MA Wragg; M Arcos; JC Arango-Viana; Jorge E Ossa; A Ruiz; Alison Goate; Francisco Lopera
E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles.
Human mutation 1997;10(3):186-95.