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Jai Shin

Research Profile

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Amino Acid Sequences

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Living Beings

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Peptic Ulcer

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Publications

TOP 3
George Sachs; Jai Shin; Richard Hunt
Novel approaches to inhibition of gastric acid secretion.
Kee Don Choi; Nayoung Kim; In-Jin Jang; Young Soo Park; Joo Youn Cho; Jung-Ryul Kim; Jai Shin; Hyun Chae Jung; In Sung Song
Optimal dose of intravenous pantoprazole in patients with peptic ulcer bleeding requiring endoscopic hemostasis in Korea.
Jai Shin; George Sachs; Young-moon Cho; Michael Garst
1-Arylsulfonyl-2-(pyridylmethylsulfinyl) benzimidazoles as new proton pump inhibitor prodrugs.

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All Publications

2010: George Sachs; Jai Shin; Richard Hunt
Novel approaches to inhibition of gastric acid secretion.
Current gastroenterology reports 2010;12(6):437-47.
2009: Kee Don Choi; Nayoung Kim; In-Jin Jang; Young Soo Park; Joo Youn Cho; Jung-Ryul Kim; Jai Shin; Hyun Chae Jung; In Sung Song
Optimal dose of intravenous pantoprazole in patients with peptic ulcer bleeding requiring endoscopic hemostasis in Korea.
Journal of gastroenterology and hepatology 2009;24(10):1617-24.
2009: Jai Shin; George Sachs; Young-moon Cho; Michael Garst
1-Arylsulfonyl-2-(pyridylmethylsulfinyl) benzimidazoles as new proton pump inhibitor prodrugs.
Molecules (Basel, Switzerland) 2009;14(12):5247-80.
2009: Jai Shin; Keith Munson; Olga Vagin; George Sachs
The gastric HK-ATPase: structure, function, and inhibition.
Pflügers Archiv : European journal of physiology 2009;457(3):609-22.
2008: Jai Shin; George Sachs
Pharmacology of proton pump inhibitors.
Current gastroenterology reports 2008;10(6):528-34.
2008: Jai Shin; George Sachs; Jeffrey A Kraut
Simple diagnostic tests to detect toxic alcohol intoxications.
Translational research : the journal of laboratory and clinical medicine 2008;152(4):194-201.
2008: Jai Shin; Olga Vagin; Keith Munson; Mark Kidd; I M Modlin; George Sachs
Molecular mechanisms in therapy of acid-related diseases.
Cellular and molecular life sciences : CMLS 2008;65(2):264-81.
2007: Cindy Zer; George Sachs; Jai Shin
Identification of genomic targets downstream of p38 mitogen-activated protein kinase pathway mediating tumor necrosis factor-alpha signaling.
Physiological genomics 2007;31(2):343-51.
2007: George Sachs; Jai Shin; Olga Vagin; Nils W G Lambrecht; Iskandar Yakubov; Keith Munson
The gastric H,K ATPase as a drug target: past, present, and future.
Journal of clinical gastroenterology 2007;41 Suppl 2():S226-42.
2007: Wolfgang Alexander Simon; M Herrmann; T Klein; Jai Shin; R Huber; Jörg Senn-Bilfinger; Stefan Postius
Soraprazan: setting new standards in inhibition of gastric acid secretion.
The Journal of pharmacology and experimental therapeutics 2007;321(3):866-74.
2006: George Sachs; Jai Shin; Colin Howden
Review article: the clinical pharmacology of proton pump inhibitors.
Alimentary pharmacology & therapeutics 2006;23 Suppl 2():2-8.
2006: Jai Shin; George Sachs
Gastric H,K-ATPase as a drug target.
Digestive diseases and sciences 2006;51(5):823-33.
2006: Jai Shin; Michel Homerin; Florence Domagala; Hervé Ficheux; George Sachs
Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo.
Biochemical pharmacology 2006;71(6):837-49.
2005: Jai Shin; Gerhard Grundler; Jörg Senn-Bilfinger; Wolfgang Alexander Simon; George Sachs
Functional consequences of the oligomeric form of the membrane-bound gastric H,K-ATPase.
Biochemistry 2005;44(49):16321-32.
2005: Olga Mareninova; Jai Shin; Olga Vagin; Shahlo Turdikulova; Stefan Hallen; George Sachs
Topography of the membrane domain of the liver Na+-dependent bile acid transporter.
Biochemistry 2005;44(42):13702-12.
2004: Jai Shin; George Sachs
Differences in binding properties of two proton pump inhibitors on the gastric H+,K+-ATPase in vivo.
Biochemical pharmacology 2004;68(11):2117-27.
2004: Jai Shin; Young Moon Cho; George Sachs
Chemistry of covalent inhibition of the gastric (H+, K+)-ATPase by proton pump inhibitors.
Journal of the American Chemical Society 2004;126(25):7800-11.
2004: George Sachs; Jai Shin
The basis of differentiation of PPIs.
Drugs of today (Barcelona, Spain : 1998) 2004;40 Suppl A():9-14.
2003: George Sachs; Jai Shin; V Pratha; D Hogan
Synthesis or rupture: duration of acid inhibition by proton pump inhibitors.
Drugs of today (Barcelona, Spain : 1998) 2003;39 Suppl A():11-4.
2002: George Sachs; Jai Shin; Olga Vagin; Keith Munson; David Weeks; David R Scott; Petra Voland
Current trends in the treatment of upper gastrointestinal disease.
Best practice & research. Clinical gastroenterology 2002;16(6):835-49.
2002: Jai Shin; George Sachs
Restoration of acid secretion following treatment with proton pump inhibitors.
Gastroenterology 2002;123(5):1588-97.
2002: Nayoung Kim; David L Weeks; Jai Shin; David R Scott; Mary K Young; George Sachs
Proteins released by Helicobacter pylori in vitro.
Journal of bacteriology 2002;184(22):6155-62.
2000: George Sachs; Jai Shin; Keith Munson; Olga Vagin; Nils W G Lambrecht; David R Scott; David L Weeks; Klaus Melchers
Review article: the control of gastric acid and Helicobacter pylori eradication.
Alimentary pharmacology & therapeutics 2000;14(11):1383-401.
2000: Keith Munson; Nils W G Lambrecht; Jai Shin; George Sachs
Analysis of the membrane domain of the gastric H(+)/K(+)-ATPase.
The Journal of experimental biology 2000;203(Pt 1):161-70.
1998: D Melle-Milovanovic; Nils W G Lambrecht; George Sachs; Jai Shin
Structural aspects of the gastric H,K ATPase: the M5/M6 domain and alpha beta association.
Acta physiologica Scandinavica. Supplementum 1998;643():147-62.
1998: D Melle-Milovanovic; M Milovanovic; S Nagpal; George Sachs; Jai Shin
Regions of association between the alpha and the beta subunit of the gastric H,K-ATPase.
The Journal of biological chemistry 1998;273(18):11075-81.
1997: Jai Shin; M Besancon; K Bamberg; George Sachs
Structural aspects of the gastric H,K ATPase.
Annals of the New York Academy of Sciences 1997;834():65-76.
1997: M Besancon; A Simon; George Sachs; Jai Shin
Sites of reaction of the gastric H,K-ATPase with extracytoplasmic thiol reagents.
The Journal of biological chemistry 1997;272(36):22438-46.
1995: George Sachs; Jai Shin; C Briving; B Wallmark; S Hersey
The pharmacology of the gastric acid pump: the H+,K+ ATPase.
Annual review of pharmacology and toxicology 1995;35():277-305.
1994: George Sachs; C Prinz; Donald D F Loo; K Bamberg; M Besancon; Jai Shin
Gastric acid secretion: activation and inhibition.
The Yale journal of biology and medicine 1994;67(3-4):81-95.
1994: Jai Shin; M Besancon; C Prinz; A Simon; George Sachs
Continuing development of acid pump inhibitors: site of action of pantoprazole.
Alimentary pharmacology & therapeutics 1994;8 Suppl 1():11-23.
1993: F Mercier; D Bayle; M Besancon; T Joys; Jai Shin; MJ Lewin; C Prinz; M A Reuben; A Soumarmon; H Wong
Antibody epitope mapping of the gastric H+/K(+)-ATPase.
Biochimica et biophysica acta 1993;1149(1):151-65.
1993: Jai Shin; M Besancon; A Simon; George Sachs
The site of action of pantoprazole in the gastric H+/K(+)-ATPase.
Biochimica et biophysica acta 1993;1148(2):223-33.
1993: M Besancon; Jai Shin; F Mercier; K Munson; M Miller; S Hersey; George Sachs
Membrane topology and omeprazole labeling of the gastric H+,K(+)-adenosinetriphosphatase.
Biochemistry 1993;32(9):2345-55.
1993: George Sachs; Jai Shin; M Besancon; C Prinz
The continuing development of gastric acid pump inhibitors.
Alimentary pharmacology & therapeutics 1993;7 Suppl 1():4-12, discussion 29-31.
1992: George Sachs; Jai Shin; M Besancon; K Munson; S Hersey
Topology and sites in the H,K-ATPase.
Annals of the New York Academy of Sciences 1992;671():204-16.
1992: George Sachs; M Besancon; Jai Shin; F Mercier; K Munson; S Hersey
Structural aspects of the gastric H,K-ATPase.
Journal of bioenergetics and biomembranes 1992;24(3):301-8.
1992: M Besancon; Jai Shin; F Mercier; K Munson; E Rabon; S Hersey; George Sachs
Chemomechanical coupling in the gastric H,K ATPase.
Acta physiologica Scandinavica. Supplementum 1992;607():77-88.