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Valerie Castle

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Chitra Subramanian; Anthony William Opipari Jr; Valerie P Castle; Manila Hada; Roland P S Kwok
CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastoma.
Karen K Winer; Laurence A Boxer; Sherin U Devaskar; GD Grave; Jennifer Guimond; Stuart Handwerger; Marc E Rothenberg; Valerie P Castle
The Child Health Research Centers: twenty-one years of promoting the development of pediatrician scientists from 1990-2011.
Kelly M Bailey; Valerie P Castle; Jennifer M Hummel; Judith Moyer; Morand Piert; Linda M McAllister-Lucas
Thalidomide therapy for aggressive histiocytic lesions in the pediatric population.

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2013: Chitra Subramanian; Anthony William Opipari Jr; Valerie P Castle; Manila Hada; Roland P S Kwok
CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastoma.
Molecular cancer research : MCR 2013;11(2):173-81.
2012: Karen K Winer; Laurence A Boxer; Sherin U Devaskar; GD Grave; Jennifer Guimond; Stuart Handwerger; Marc E Rothenberg; Valerie P Castle
The Child Health Research Centers: twenty-one years of promoting the development of pediatrician scientists from 1990-2011.
The Journal of pediatrics 2012;161(6):975-6.
2012: Kelly M Bailey; Valerie P Castle; Jennifer M Hummel; Judith Moyer; Morand Piert; Linda M McAllister-Lucas
Thalidomide therapy for aggressive histiocytic lesions in the pediatric population.
Journal of pediatric hematology/oncology 2012;34(6):480-3.
2011: Eric J Dziuban; Valerie P Castle; Hilary M Haftel
Microscopic polyangiitis in an adolescent presenting as severe anemia and syncope.
Rheumatology international 2011;31(11):1507-10.
2011: Chitra Subramanian; Anthony William Opipari Jr; Valerie P Castle; Jason A Jarzembowski; Roland P S Kwok
HDAC6 deacetylates Ku70 and regulates Ku70-Bax binding in neuroblastoma.
Neoplasia (New York, N.Y.) 2011;13(8):726-34.
2011: Chitra Subramanian; Jason A Jarzembowski; Sonja M Halsey; Rork Kuick; Anthony William Opipari Jr; Valerie P Castle; Roland P S Kwok
CLU blocks HDACI-mediated killing of neuroblastoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2011;32(2):285-94.
2011: Justin Hurie; Peter F Ehrlich; Valerie P Castle; Jonathan L Eliason
Isolated infrarenal caval disruption secondary to minimal blunt trauma.
Annals of vascular surgery 2011;25(1):132.e13-5.
2010: Julie C Lumeng; Valerie P Castle; Carey N Lumeng
The role of pediatricians in the coordinated national effort to address childhood obesity.
Pediatrics 2010;126(3):574-5.
2010: Rajen J Mody; Chuong Bui; Raymond J Hutchinson; Gregory Yanik; Valerie P Castle; Kirk A Frey; Barry L Shulkin
FDG PET imaging of childhood sarcomas.
Pediatric blood & cancer 2010;54(2):222-7.
2010: Valerie P Castle; Roland P S Kwok; Anthony William Opipari Jr; Chitra Subramanian
Ku70 acetylation in neuroblastoma pathogenesis and therapy.
Transactions of the American Clinical and Climatological Association 2010;121():183-91; discussion 191.
2009: Aghiad Chamdin; Jason A Jarzembowski; Chitra Subramanian; Rork Kuick; Julia Shin-Jung Lee; Roland P S Kwok; Valerie P Castle; Anthony William Opipari Jr
Bcl6 is expressed in neuroblastoma: tumor cell type-specific expression predicts outcome.
Translational oncology 2009;2(3):128-37.
2008: Peter E Newburger; Valerie P Castle
The American Society of Pediatric Hematology/Oncology distinguished career award goes to Laurence A. Boxer, MD.
Pediatric blood & cancer 2008;50(6):1121-2.
2008: Michael B Armstrong; Kurt R Schumacher; Rajen J Mody; Gregory Yanik; Anthony William Opipari Jr; Valerie P Castle
Bortezomib as a therapeutic candidate for neuroblastoma.
Journal of experimental therapeutics & oncology 2008;7(2):135-45.
2007: Chitra Subramanian; Jason A Jarzembowski; Anthony William Opipari Jr; Valerie P Castle; Roland P S Kwok
CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A.
Neoplasia (New York, N.Y.) 2007;9(6):495-503.
2007: Matthew Mischler; Geoffrey M Fleming; Thomas P Shanley; Lisa Madden; John E Levine; Valerie P Castle; Alexandra H Filipovich; Timothy T Cornell
Epstein-Barr virus-induced hemophagocytic lymphohistiocytosis and X-linked lymphoproliferative disease: a mimicker of sepsis in the pediatric intensive care unit.
Pediatrics 2007;119(5):e1212-8.
2007: Darryl T Martin; Robert L Gendron; Jason A Jarzembowski; Arie Perry; Margaret H Collins; Chitra Pushpanathan; Ewa Miskiewicz; Valerie P Castle; Hélène Paradis
Tubedown expression correlates with the differentiation status and aggressiveness of neuroblastic tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(5):1480-7.
2006: Michael B Armstrong; Xin Bian; Yihong Liu; Chitra Subramanian; Anthony B Ratanaproeksa; Feng Shao; Victor C Yu; Roland P S Kwok; Anthony William Opipari Jr; Valerie P Castle
Signaling from p53 to NF-kappa B determines the chemotherapy responsiveness of neuroblastoma.
Neoplasia (New York, N.Y.) 2006;8(11):964-74.
2006: Michael B Armstrong; Xin Bian; Yihong Liu; Chitra Subramanian; Anthony B Ratanaproeksa; Feng Shao; Victor C Yu; Roland P S Kwok; Anthony William Opipari Jr; Valerie P Castle
Signaling from p53 to NF-kappaB determines the chemotherapy responsiveness of neuroblastoma.
Neoplasia (New York, N.Y.) 2006;8(11):967-77.
2006: Aruna Basu; Valerie P Castle; Mohammed Bouziane; Kapil N Bhalla; Subrata Haldar
Crosstalk between extrinsic and intrinsic cell death pathways in pancreatic cancer: synergistic action of estrogen metabolite and ligands of death receptor family.
Cancer research 2006;66(8):4309-18.
2005: Chitra Subramanian; Anthony William Opipari Jr; Valerie P Castle; Roland P S Kwok
Histone deacetylase inhibition induces apoptosis in neuroblastoma.
Cell cycle (Georgetown, Tex.) 2005;4(12):1741-3.
2005: William D Lyman; Charles Barone II; Valerie P Castle; H Dele Davies; Bonita Stanton; Nigel Paneth
Making the National Children's Study a real partnership with academic pediatrics.
The Journal of pediatrics 2005;147(5):563-4.
2005: Michael B Armstrong; Patricia L Robertson; Valerie P Castle
Delayed, recurrent opsoclonus-myoclonus syndrome responding to plasmapheresis.
Pediatric neurology 2005;33(5):365-7.
2005: Chitra Subramanian; Anthony William Opipari Jr; Xin Bian; Valerie P Castle; Roland P S Kwok
Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(13):4842-7.
2005: Courtney D Thornburg; Diane Roulston; Valerie P Castle
Burkitt lymphoma and Williams syndrome: a model for children with a multisystem disorder and malignancy.
Journal of pediatric hematology/oncology 2005;27(2):109-11.
2005: Craig A McKinney; James Geiger; Valerie P Castle; Robert E Ruiz; Peter J Strouse
Aggressive hepatic angiomyolipoma in a child.
Pediatric hematology and oncology 2005;22(1):17-24.
2004: BRIGITTE WIDEMANN; FRANK BALIS; Aiman Shalabi; Matthew Boron; Michelle O'Brien; Diane E Cole; Nalini Jayaprakash; Percy Ivy; Valerie P Castle; Karin M Muraszko; Christopher L Moertel; Robert Trueworthy; Robert C Hermann; Ali Moussa; Stuart Hinton; Gregory Reaman; David G Poplack; Peter Charles Adamson
Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2.
Journal of the National Cancer Institute 2004;96(20):1557-9.
2004: Xin Bian; Thomas J Giordano; Huey-Jen Lin; Gabriel Solomon; Valerie P Castle; Anthony William Opipari Jr
Chemotherapy-induced apoptosis of S-type neuroblastoma cells requires caspase-9 and is augmented by CD95/Fas stimulation.
The Journal of biological chemistry 2004;279(6):4663-9.
2003: Courtney D Thornburg; Barry L Shulkin; Valerie P Castle; Linda M McAllister-Lucas
Thoracic neural crest tumors in Beckwith-Wiedemann syndrome.
Medical and pediatric oncology 2003;41(5):468-9.
2002: Xin Bian; Anthony William Opipari Jr; Anthony B Ratanaproeksa; Anthony E Boitano; Peter C Lucas; Valerie P Castle
Constitutively active NFkappa B is required for the survival of S-type neuroblastoma.
The Journal of biological chemistry 2002;277(44):42144-50.
2002: Xiaoxiang Zhu; Katharina Wimmer; Rork Kuick; Barbara J Lamb; Stephanie Motyka; Rama Jasty; Valerie P Castle; Samir M Hanash
N-myc modulates expression of p73 in neuroblastoma.
Neoplasia (New York, N.Y.) 2002;4(5):432-9.
2001: Xin Bian; Linda M McAllister-Lucas; Feng Shao; K R Schumacher; Z Feng; A G Porter; Valerie P Castle; Anthony William Opipari Jr
NF-kappa B activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells.
The Journal of biological chemistry 2001;276(52):48921-9.
2001: Rama Jasty; Cynthia M van Golen; H J Lin; G Solomon; K Heidelberger; Peter J Polverini; Anthony William Opipari Jr; Eva L Feldman; Valerie P Castle
Bcl-2 and M-Myc coexpression increases IGF-IR and features of malignant growth in neuroblastoma cell lines.
Neoplasia (New York, N.Y.) 2001;3(4):304-13.
2000: Elizabeth M Petty; Gregory Yanik; Raymond J Hutchinson; BLANCHE ALTER; Frank C Schmalstieg; John E Levine; David Ginsburg; J E Robillard; Valerie P Castle
Successful bone marrow transplantation in a patient with Schimke immuno-osseous dysplasia.
The Journal of pediatrics 2000;137(6):882-6.
2000: Rama Jasty; Peter J Strouse; Valerie P Castle
Fatal lymphoproliferative disease as a complication of Evans syndrome.
Journal of pediatric hematology/oncology 2000;22(5):460-3.
2000: Cynthia M van Golen; Valerie P Castle; Eva L Feldman
IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma.
Cell death and differentiation 2000;7(7):654-65.
2000: Mark R Hemmila; David S Foley; Valerie P Castle; Ronald B Hirschl
The response to splenectomy in pediatric patients with idiopathic thrombocytopenic purpura who fail high-dose intravenous immune globulin.
Journal of pediatric surgery 2000;35(6):967-71; discussion 971-2.
2000: Jacques E Nor; Raj S Mitra; M M Sutorik; D J Mooney; Valerie P Castle; Peter J Polverini
Thrombospondin-1 induces endothelial cell apoptosis and inhibits angiogenesis by activating the caspase death pathway.
Journal of vascular research 2000;37(3):209-18.
2000: C Page; Huey-Jen Lin; Y Jin; Valerie P Castle; Gabriel Nunez; M Huang; Jiayuh Lin
Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis.
Anticancer research 2000;20(1A):407-16.
1999: Latha Prasannan; AT Pu; P Hoff; Robert A Weatherly; Valerie P Castle
Parotid carcinoma as a second malignancy after treatment of childhood acute lymphoblastic leukemia.
Journal of pediatric hematology/oncology 1999;21(6):535-8.
1998: Rama Jasty; J Lu; T Irwin; S Suchard; M F Clarke; Valerie P Castle
Role of p53 in the regulation of irradiation-induced apoptosis in neuroblastoma cells.
Molecular genetics and metabolism 1998;65(2):155-64.
1998: GM Weiner; Valerie P Castle; Michael A DiPietro; Roger G Faix
Successful treatment of neonatal arterial thromboses with recombinant tissue plasminogen activator.
The Journal of pediatrics 1998;133(1):133-6.
1997: T Wrone-Smith; Raj S Mitra; Craig Thompson; Rama Jasty; Valerie P Castle; Brian J Nickoloff
Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin.
The American journal of pathology 1997;151(5):1321-9.
1997: Valerie P Castle; V M Dixit; Peter J Polverini
Thrombospondin-1 suppresses tumorigenesis and angiogenesis in serum- and anchorage-independent NIH 3T3 cells.
Laboratory investigation; a journal of technical methods and pathology 1997;77(1):51-61.
1997: E Chang; A Boyd; C C Nelson; Dennis C Crowley; T Law; K M Keough; J Folkman; R A Ezekowitz; Valerie P Castle
Successful treatment of infantile hemangiomas with interferon-alpha-2b.
Journal of pediatric hematology/oncology 1997;19(3):237-44.
1997: J P Donnelly; Amnon Rosenthal; Valerie P Castle; Ronald D Holmes
Reversal of protein-losing enteropathy with heparin therapy in three patients with univentricular hearts and Fontan palliation.
The Journal of pediatrics 1997;130(3):474-8.
1996: M G Dole; Michael F Clarke; P Holman; MA Benedict; J Lu; Rama Jasty; P Eipers; Craig Thompson; CK Rode; Craig A Bloch; Valerie P Castle
Bcl-xS enhances adenoviral vector-induced apoptosis in neuroblastoma cells.
Cancer research 1996;56(24):5734-40.
1996: Richard J O'Reilly; Nai-Kong V Cheung; L Bowman; Valerie P Castle; F Hoffer; N Kapoor; M Kletzel; KL Lindsley; R Shamberger; D Tubergen
NCCN pediatric neuroblastoma practice guidelines. The National Comprehensive Cancer Network.
Oncology (Williston Park, N.Y.) 1996;10(12):1813-22.
1996: Barry L Shulkin; Raymond J Hutchinson; Valerie P Castle; Gregory Yanik; Brahm Shapiro; James C Sisson
Neuroblastoma: positron emission tomography with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose compared with metaiodobenzylguanidine scintigraphy.
Radiology 1996;199(3):743-50.
1996: Steven W Pipe; Alvin H Schmaier; William C Nichols; David Ginsburg; Mary Ellen A Hernandez; Valerie P Castle
Neonatal purpura fulminans in association with factor V R506Q mutation.
The Journal of pediatrics 1996;128(5 Pt 1):706-9.
1996: Barry L Shulkin; Darryl Wieland; M E Baro; D R Ungar; D S Mitchell; M G Dole; J B Rawwas; Valerie P Castle; James C Sisson; Raymond J Hutchinson
PET hydroxyephedrine imaging of neuroblastoma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(1):16-21.
1995: Kelli A Sullivan; Valerie P Castle; S M Hanash; Eva L Feldman
Insulin-like growth factor II in the pathogenesis of human neuroblastoma.
The American journal of pathology 1995;147(6):1790-8.
1995: A E Schlesinger; N S Rosenfield; Valerie P Castle; Rama Jasty
Congenital mesoblastic nephroma metastatic to the brain: a report of two cases.
Pediatric radiology 1995;25 Suppl 1():S73-5.
1995: M G Dole; Rama Jasty; Max D Cooper; Craig Thompson; Gabriel Nuñez; Valerie P Castle
Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis.
Cancer research 1995;55(12):2576-82.
1995: Barry L Shulkin; D S Mitchell; D R Ungar; D Prakash; M G Dole; Valerie P Castle; Ramiro J Hernandez; Robert A Koeppe; Raymond J Hutchinson
Neoplasms in a pediatric population: 2-[F-18]-fluoro-2-deoxy-D-glucose PET studies.
Radiology 1995;194(2):495-500.
1994: M Dole; Gabriel Nuñez; A K Merchant; Jonathan Maybaum; CK Rode; Craig A Bloch; Valerie P Castle
Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma.
Cancer research 1994;54(12):3253-9.
1994: D A Reardon; C A Hanson; M S Roth; Valerie P Castle
Lineage switch in Philadelphia chromosome-positive acute lymphoblastic leukemia.
Cancer 1994;73(5):1526-32.
1993: Valerie P Castle; Kathleen P Heidelberger; Jonathan Bromberg; X Ou; M Dole; Gabriel Nuñez
Expression of the apoptosis-suppressing protein bcl-2, in neuroblastoma is associated with unfavorable histology and N-myc amplification.
The American journal of pathology 1993;143(6):1543-50.
1993: Valerie P Castle; X Ou; K O'Rourke; Xiaodong Huang
High level thrombospondin 1 expression in two NIH 3T3 cloned lines confers serum- and anchorage-independent growth.
The Journal of biological chemistry 1993;268(4):2899-903.
1992: Valerie P Castle; X Ou; K Sue O'Shea; Xiaodong Huang
Induction of thrombospondin 1 by retinoic acid is important during differentiation of neuroblastoma cells.
The Journal of clinical investigation 1992;90(5):1857-63.
1991: Valerie P Castle; James Varani; S Fligiel; Edward V Prochownik; V Dixit
Antisense-mediated reduction in thrombospondin reverses the malignant phenotype of a human squamous carcinoma.
The Journal of clinical investigation 1991;87(6):1883-8.
1991: D A Reardon; R Roskos; C A Hanson; Valerie P Castle
Virus-associated hemophagocytic syndrome following bone marrow transplantation.
The American journal of pediatric hematology/oncology 1991;13(3):305-9.
1990: Barry L Shulkin; Louis C Argenta; Kyung J Cho; Valerie P Castle
Kasabach-Merritt syndrome: treatment with epsilon-aminocaproic acid and assessment by indium 111 platelet scintigraphy.
The Journal of pediatrics 1990;117(5):746-9.
1989: Valerie P Castle; Barry L Shulkin; G Coates; M Andrew
The use of indium-111 oxine platelet scintigraphy and survival studies in pediatric patients with thrombocytopenia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1989;30(11):1819-24.
1989: Maureen Andrew; Valerie P Castle; Lesley Mitchell; Bosco Paes
Modified bleeding time in the infant.
American journal of hematology 1989;30(3):190-1.
1988: Maureen Andrew; Bosco Paes; R Milner; Marilyn Johnston; Lesley Mitchell; D M Tollefsen; Valerie P Castle; P Powers
Development of the human coagulation system in the healthy premature infant.
Blood 1988;72(5):1651-7.
1988: Valerie P Castle; Geoffrey Coates; L G Mitchell; H O'Brodovich; Maureen Andrew
The effect of hypoxia on platelet survival and site of sequestration in the newborn rabbit.
Thrombosis and haemostasis 1988;59(1):45-8.
1987: Valerie P Castle; G Coates; J G Kelton; M Andrew
111In-oxine platelet survivals in thrombocytopenic infants.
Blood 1987;70(3):652-6.
1987: M Andrew; Valerie P Castle; S Saigal; C Carter; J G Kelton
Clinical impact of neonatal thrombocytopenia.
The Journal of pediatrics 1987;110(3):457-64.
1986: Valerie P Castle; M Andrew; J Kelton; D Giron; M Johnston; C Carter
Frequency and mechanism of neonatal thrombocytopenia.
The Journal of pediatrics 1986;108(5 Pt 1):749-55.