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Beverly Castner

Research Profile

Chemicals & Drugs

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Publications

TOP 3
David C Lee; Susan W Sunnarborg; C Leann Hinkle; Timothy J Myers; Mary Y Stevenson; William E Russell; Beverly J Castner; Mary J Gerhart; Raymond J Paxton; Roy A Black; Aileen Chang; Leslie F Jackson
TACE/ADAM17 processing of EGFR ligands indicates a role as a physiological convertase.
Roy A Black; John R Doedens; Rajeev Mahimkar; Richard Johnson; Lin Guo; Alison Wallace; Duke Virca; June Eisenman; Jennifer Slack; Beverly J Castner; Susan W Sunnarborg; David C Lee; Rebecca Cowling; Guixian Jin; Keith Charrier; Jacques J Peschon; Raymond J Paxton
Substrate specificity and inducibility of TACE (tumour necrosis factor alpha-converting enzyme) revisited: the Ala-Val preference, and induced intrinsic activity.
Susan W Sunnarborg; C Leann Hinkle; Mary Stevenson; William E Russell; Christina S Raska; Jacques J Peschon; Beverly J Castner; Mary J Gerhart; Raymond J Paxton; Roy A Black; David C Lee
Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability.

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All Publications

2003: David C Lee; Susan W Sunnarborg; C Leann Hinkle; Timothy J Myers; Mary Y Stevenson; William E Russell; Beverly J Castner; Mary J Gerhart; Raymond J Paxton; Roy A Black; Aileen Chang; Leslie F Jackson
TACE/ADAM17 processing of EGFR ligands indicates a role as a physiological convertase.
Annals of the New York Academy of Sciences 2003;995():22-38.
2003: Roy A Black; John R Doedens; Rajeev Mahimkar; Richard Johnson; Lin Guo; Alison Wallace; Duke Virca; June Eisenman; Jennifer Slack; Beverly J Castner; Susan W Sunnarborg; David C Lee; Rebecca Cowling; Guixian Jin; Keith Charrier; Jacques J Peschon; Raymond J Paxton
Substrate specificity and inducibility of TACE (tumour necrosis factor alpha-converting enzyme) revisited: the Ala-Val preference, and induced intrinsic activity.
Biochemical Society symposium 2003;(70):39-52.
2002: Susan W Sunnarborg; C Leann Hinkle; Mary Stevenson; William E Russell; Christina S Raska; Jacques J Peschon; Beverly J Castner; Mary J Gerhart; Raymond J Paxton; Roy A Black; David C Lee
Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability.
The Journal of biological chemistry 2002;277(15):12838-45.
1999: Douglas Pat Cerretti; K Poindexter; Beverly J Castner; G Means; N G Copeland; D J Gilbert; N A Jenkins; Roy A Black; N Nelson
Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25.
Cytokine 1999;11(8):541-51.
1998: Jacques J Peschon; JL Slack; P Reddy; Kim L Stocking; Susan W Sunnarborg; David C Lee; William E Russell; Beverly J Castner; Richard S Johnson; JN Fitzner; R W Boyce; N Nelson; Carl J Kozlosky; Martin F Wolfson; Charles T Rauch; Douglas Pat Cerretti; Raymond J Paxton; CJ March; Roy A Black
An essential role for ectodomain shedding in mammalian development.
Science (New York, N.Y.) 1998;282(5392):1281-4.
1998: Joseph Buxbaum; K N Liu; Y Luo; JL Slack; Kim L Stocking; Jacques J Peschon; Richard S Johnson; Beverly J Castner; Douglas Pat Cerretti; Roy A Black
Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor.
The Journal of biological chemistry 1998;273(43):27765-7.
1998: H R Clarke; Martin F Wolfson; Charles T Rauch; Beverly J Castner; C P Huang; Mary J Gerhart; Richard S Johnson; Douglas Pat Cerretti; Raymond J Paxton; V L Price; Roy A Black
Expression and purification of correctly processed, active human TACE catalytic domain in Saccharomyces cerevisiae.
Protein expression and purification 1998;13(1):104-10.
1998: Klaus Maskos; Carlos Fernandez-Catalan; Robert Huber; Gleb P Bourenkov; Hans D Bartunik; G A Ellestad; P Reddy; Martin F Wolfson; Charles T Rauch; Beverly J Castner; R Davis; H R Clarke; M Petersen; JN Fitzner; Douglas Pat Cerretti; CJ March; Raymond J Paxton; Roy A Black; Wolfram Bode
Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3408-12.
1997: Roy A Black; Charles T Rauch; Carl J Kozlosky; Jacques J Peschon; JL Slack; Martin F Wolfson; Beverly J Castner; Kim L Stocking; P Reddy; S Srinivasan; N Nelson; Norman Boiani; Kenneth Schooley; Mary J Gerhart; R Davis; JN Fitzner; Richard S Johnson; Raymond J Paxton; CJ March; Douglas Pat Cerretti
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.
Nature 1997;385(6618):729-33.
1997: J Müllberg; Charles T Rauch; Martin F Wolfson; Beverly J Castner; JN Fitzner; C Otten-Evans; Ken Mohler; David Cosman; Roy A Black
Further evidence for a common mechanism for shedding of cell surface proteins.
FEBS letters 1997;401(2-3):235-8.
1996: Roy A Black; F H Durie; C Otten-Evans; R Miller; JL Slack; D H Lynch; Beverly J Castner; K M Mohler; Mary J Gerhart; Richard S Johnson; Y Itoh; Y Okada; H Nagase
Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-alpha (TNF-alpha) production suggest the major TNF-alpha converting enzyme is not an MMP.
Biochemical and biophysical research communications 1996;225(2):400-5.
1996: R C Hoffman; Franklin J Moy; V Price; J Richardson; D Kaubisch; E A Frieden; J D Krakover; Beverly J Castner; J King; CJ March; Robert Powers
Resonance assignments for Oncostatin M, a 24-kDa alpha-helical protein.
Journal of biomolecular NMR 1996;7(4):273-82.
1995: R C Hoffman; Beverly J Castner; Mary J Gerhart; M G Gibson; B D Rasmussen; CJ March; J Weatherbee; M Tsang; Alla Gustchina; C Schalk-Hihi
Direct evidence of a heterotrimeric complex of human interleukin-4 with its receptors.
Protein science : a publication of the Protein Society 1995;4(3):382-6.
1994: R C Hoffman; C Schalk-Hihi; Beverly J Castner; M G Gibson; B D Rasmussen; Alexander Zdanov; Alla Gustchina; CJ March; Alexander Wlodawer
Stoichiometry of the complex of human interleukin-4 with its receptor.
FEBS letters 1994;347(1):17-21.