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Vadivel Ganapathy

Research Profile

Chemicals & Drugs

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TOP 3
Prem S Shekhawat; Srinivas Sonne; Alva Lee Carter; Dietrich Matern; Vadivel Ganapathy
Enzymes involved in l-carnitine biosynthesis are expressed by small intestinal enterocytes in mice: Implications for gut health.
Shanu Markand; Nilkantha Sen; Vadivel Ganapathy; Jaya Gnana-Prakasam; Yonju Ha; Srinivas Sonne; Amany Tawfik; Ming Xian; Sylvia B Smith
Cystathionine beta synthase expression in mouse retina.
Paresh P Chothe; Norman B. Chutkan; Vadivel Ganapathy; Mark W Hamrick; Carlos M. Isales; Puttur D Prasad; Rajnikumar Sangani; Muthusamy Thangaraju; Karl H Wenger; Sadanand Fulzele
Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells.

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2013: Prem S Shekhawat; Srinivas Sonne; Alva Lee Carter; Dietrich Matern; Vadivel Ganapathy
Enzymes involved in l-carnitine biosynthesis are expressed by small intestinal enterocytes in mice: Implications for gut health.
Journal of Crohn's & colitis 2013;7(6):e197-205.
2013: Shanu Markand; Nilkantha Sen; Vadivel Ganapathy; Jaya Gnana-Prakasam; Yonju Ha; Srinivas Sonne; Amany Tawfik; Ming Xian; Sylvia B Smith
Cystathionine beta synthase expression in mouse retina.
Current eye research 2013;38(5):597-604.
2013: Paresh P Chothe; Norman B. Chutkan; Vadivel Ganapathy; Mark W Hamrick; Carlos M. Isales; Puttur D Prasad; Rajnikumar Sangani; Muthusamy Thangaraju; Karl H Wenger; Sadanand Fulzele
Sodium-coupled vitamin C transporter (SVCT2): expression, function, and regulation in intervertebral disc cells.
The spine journal : official journal of the North American Spine Society 2013;13(5):549-57.
2013: Veena Coothankandaswamy; Selvakumar Elangovan; Puttur D Prasad; Nagendra Singh; Muthusamy Thangaraju; Vadivel Ganapathy
The plasma membrane transporter SLC5A8 suppresses tumour progression through depletion of survivin without involving its transport function.
The Biochemical journal 2013;450(1):169-78.
2013: Jan Lewerenz; Vadivel Ganapathy; Peter W Gout; Sandra J Hewett; Ying Huang; Peter W Kalivas; Maria Lambros; Ann Massie; Axel Methner; Mathias Pergande; Sylvia B Smith; Ilse Smolders; Pamela Maher
The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.
Antioxidants & redox signaling 2013;18(5):522-55.
2013: Parameswaran G Sreekumar; Rinku Baid; Paresh Chothe; Vadivel Ganapathy; Nandini Kannan; Ram Kannan; Uday Kompella; Christina Manh; Stephen J Ryan; Krishna K Sharma; Christine Spee; David R Hinton
Antiapoptotic Properties of α-Crystallin-Derived Peptide Chaperones and Characterization of Their Uptake Transporters in Human RPE Cells.
Investigative ophthalmology & visual science 2013;54(4):2787-98.
2013: Amany Tawfik; Srinivas Sonne; Mohamed Al-Shabrawey; Sally S Atherton; Jason A Covar; Azza B El-Remessy; Preethi S Ganapathy; Vadivel Ganapathy; Suraporn Matragoon; Penny Roon; Sylvia B Smith
Alterations of retinal vasculature in cystathionine-Beta-synthase mutant mice, a model of hyperhomocysteinemia.
Investigative ophthalmology & visual science 2013;54(2):939-49.
2013: Jaya P Gnana-Prakasam; Pamela M Martin; Sushma K Reddy; Sylvia B Smith; Muthusamy Thangaraju; Rajalakshmi Veeranan-Karmegam; Veena Coothankandaswamy; Vadivel Ganapathy
Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2013;54(1):63-71.
2013: Sadanand Fulzele; Maryka Bhattacharyya; Matthew Bowser; Paresh Chothe; Norman B. Chutkan; Mark Hamrick; Carlos Isales; Puttur D Prasad; Rajnikumar Sangani; Ibrahim Zakhary; Vadivel Ganapathy
Sodium-dependent vitamin C transporter SVCT2: expression and function in bone marrow stromal cells and in osteogenesis.
Stem cell research 2013;10(1):36-47.
2012: Riyaz Mohamed; Vadivel Ganapathy; Calpurnia Jayakumar; Punithavathi V Ranganathan; Ganesan Ramesh
Kidney proximal tubular epithelial-specific overexpression of netrin-1 suppresses inflammation and albuminuria through suppression of COX-2-mediated PGE2 production in streptozotocin-induced diabetic mice.
The American journal of pathology 2012;181(6):1991-2002.
2012: James Helm; Mark Lloyd; Mokenge P Malafa; Barbara A Centeno; Dung-Tsa Chen; Domenico Coppola; Vadivel Ganapathy; Jong Y Park
SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma.
Pancreas 2012;41(6):904-9.
2012: Feiyan Liu; Muthusamy Thangaraju; Jennifer L Waller; Dafeng Yang; Kankana Bardhan; Vadivel Ganapathy; Jeffrey R Lee; Georgia B Liles; Kebin Liu
NF-κB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression.
The Journal of biological chemistry 2012;287(30):25530-40.
2012: Rui Wang; Vadivel Ganapathy; Franz Hofmann; Philippe Jay; In-Kiu Kwon; Kebin Liu; Nagendra Singh; Muthusamy Thangaraju; Darren Browning
Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa.
American journal of physiology. Gastrointestinal and liver physiology 2012;303(2):G209-19.
2012: Mary A Zimmerman; Vadivel Ganapathy; Pamela M Martin; David H Munn; Keith D Robertson; Huidong Shi; Nagendra Singh; Muthusamy Thangaraju; Jennifer L Waller; Kebin Liu
Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(12):G1405-15.
2012: Shiro Itagaki; Ellappan Babu; Vadivel Ganapathy; Horace T B Ho; Mingyan Zhou; Joanne Wang
Electrophysiological characterization of the polyspecific organic cation transporter plasma membrane monoamine transporter.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(6):1138-43.
2012: Deeksha Gambhir; Vadivel Ganapathy; Shanterian Hester; Eric Jennings; Julian J Nussbaum; Stefan Offermanns; Sylvia B Smith; Muthusamy Thangaraju; Rajalakshmi Veeranan-Karmegam; Sudha Ananth; Selvakumar Elangovan; Pamela M Martin
GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.
Investigative ophthalmology & visual science 2012;53(4):2208-17.
2012: B Renee Bozard; Paresh P Chothe; Sadanand Fulzele; Vadivel Ganapathy; Pamela M Martin; Puttur D Prasad; Amany Tawfik; Cory Williams; Sylvia B Smith
Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate.
Glia 2012;60(3):333-42.
2012: Jaya P Gnana-Prakasam; Michelle Romej; Sudha Ananth; Sylvia B Smith; Pamela M Martin; Amany Tawfik; Vadivel Ganapathy
Iron-mediated retinal degeneration in haemojuvelin-knockout mice.
The Biochemical journal 2012;441(2):599-608.
2012: Yonju Ha; Alan Saul; Amany Tawfik; Eric P Zorrilla; Vadivel Ganapathy; Sylvia B Smith
Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1.
Molecular vision 2012;18():2860-70.
2012: Srinivas Sonne; Vadivel Ganapathy; Dietrich Matern; Prem S Shekhawat; Leszek Ignatowicz
Carnitine deficiency in OCTN2-/- newborn mice leads to a severe gut and immune phenotype with widespread atrophy, apoptosis and a pro-inflammatory response.
PloS one 2012;7(10):e47729.
2012: Sudha Ananth; Preethi S Ganapathy; Jaya P Gnana-Prakasam; Pamela Moore Martin; Sylvia B Smith; Santoshanand V Thakkar; Vadivel Ganapathy
Transport of the synthetic opioid peptide DADLE ([D-Ala2,D-Leu5]-enkephalin) in neuronal cells.
Journal of pharmaceutical sciences 2012;101(1):154-63.
2011: Jaya P Gnana-Prakasam; Pamela Moore Martin; Sushma K Reddy; Sylvia B Smith; Rajalakshmi Veeranan-Karmegam; Vadivel Ganapathy
Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis.
Investigative ophthalmology & visual science 2011;52(12):9279-86.
2011: Selvakumar Elangovan; Vadivel Ganapathy; Jaya P Gnana-Prakasam; Pamela Moore Martin; Puttur D Prasad; Sabarish Ramachandran; Patricia V Schoenlein; Sudha Ananth; Darren Browning; Narayanan Venkatesan; Muthusamy Thangaraju
SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer.
Cancer research 2011;71(21):6654-64.
2011: Masanori Tachikawa; Ken-ichi Hosoya; Pamela Moore Martin; Koji Murakami; Vadivel Ganapathy
Retinal transfer of nicotinate by H+ -monocarboxylate transporter at the inner blood-retinal barrier.
Microvascular research 2011;82(3):385-90.
2011: Hui-Yi Lin; Nupam P Mahajan; Hyun Y Park; Julio Pow-Sang; Selina Radlein; Thomas A Sellers; Babu Zachariah; Domenico Coppola; Vadivel Ganapathy; Jong Y Park
Protein expressions and genetic variations of SLC5A8 in prostate cancer risk and aggressiveness.
Urology 2011;78(4):971.e1-9.
2011: Ellappan Babu; V CoothanKandaswamy; S Elangovan; Vadivel Ganapathy; Puttur D Prasad; S Ramachandran; Muthusamy Thangaraju
Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate.
Oncogene 2011;30(38):4026-37.
2011: Senthil Karunakaran; Sudharsan Periyasamy-Thandavan; Puttur D Prasad; Sabarish Ramachandran; Patricia V Schoenlein; Nagendra Singh; Muthusamy Thangaraju; Ellappan Babu; Veena Coothankandaswamy; Selvakumar Elangovan; Jaya P Gnanaprakasam; Ashish Gurav; Vadivel Ganapathy
SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer.
The Journal of biological chemistry 2011;286(36):31830-8.
2011: Yonju Ha; Alan B Saul; Robert Smith; Masanori Tachikawa; Amany Tawfik; Cory Williams; Eric Zorrilla; Kathryn Bollinger; Vadivel Ganapathy; Sylvia B Smith
Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1).
Investigative ophthalmology & visual science 2011;52(10):7749-60.
2011: Ellappan Babu; Thomas Boettger; Veena Coothankandaswamy; Vadivel Ganapathy; Sylvia B Smith; Rajalakshmi Veeranan-Karmegam; Sudha Ananth; Pamela Moore Martin
Transport via SLC5A8 (SMCT1) is obligatory for 2-oxothiazolidine-4-carboxylate to enhance glutathione production in retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2011;52(8):5749-57.
2011: Paresh Chothe; Nagendra Singh; Vadivel Ganapathy
Evidence for two different broad-specificity oligopeptide transporters in intestinal cell line Caco-2 and colonic cell line CCD841.
American journal of physiology. Cell physiology 2011;300(6):C1260-9.
2011: Vadivel Ganapathy
Drugs of abuse and human placenta.
Life sciences 2011;88(21-22):926-30.
2011: Hong-ming Li; Mei Zhang; Sheng-tao Xu; Di-zheng Li; Lin-yun Zhu; Si-wu Peng; Guo-qiang Chen; Pamela Moore Martin; Vadivel Ganapathy; Chi-ju Wei
Nicotinic acid inhibits glucose-stimulated insulin secretion via the G protein-coupled receptor PUMA-G in murine islet β cells.
Pancreas 2011;40(4):615-21.
2011: Jaya P Gnana-Prakasam; Sudha Ananth; Puttur D Prasad; Ming Zhang; Sally Atherton; Pamela Moore Martin; Sylvia B Smith; Vadivel Ganapathy
Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium.
Investigative ophthalmology & visual science 2011;52(6):3751-8.
2011: Paresh P Chothe; Jaya P Gnana-Prakasam; Sudha Ananth; Pamela Moore Martin; Ram Kannan; David R Hinton; Sylvia B Smith; Vadivel Ganapathy
Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis.
Biochemical and biophysical research communications 2011;405(2):244-9.
2011: Yonju Ha; Ying Dun; Muthusamy Thangaraju; Jennifer Duplantier; Zheng Dong; Kebin Liu; Vadivel Ganapathy; Sylvia B Smith
Sigma receptor 1 modulates endoplasmic reticulum stress in retinal neurons.
Investigative ophthalmology & visual science 2011;52(1):527-40.
2011: Noel Edwards; Catriona M H Anderson; Kelly M Gatfield; Mark P Jevons; Vadivel Ganapathy; David T Thwaites
Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2).
Biochimica et biophysica acta 2011;1808(1):260-70.
2010: Yong Li; Maoxiang Zhang; Huijun Chen; Zheng Dong; Vadivel Ganapathy; Muthusamy Thangaraju; Shuang Huang
Ratio of miR-196s to HOXC8 messenger RNA correlates with breast cancer cell migration and metastasis.
Cancer research 2010;70(20):7894-904.
2010: Xuetao Fan; Douglas Ross; Hiroshi Arakawa; Vadivel Ganapathy; Ikumi Tamai; Takeo Nakanishi
Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: a possible target for combination therapy with anti-proliferative aminopeptidase inhibitors.
Biochemical pharmacology 2010;80(6):811-8.
2010: Nagendra Singh; Muthusamy Thangaraju; Puttur D Prasad; Pamela Moore Martin; Nevin A Lambert; Thomas Boettger; Stefan Offermanns; Vadivel Ganapathy
Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases.
The Journal of biological chemistry 2010;285(36):27601-8.
2010: Pavan K Kommareddi; Thankam S Nair; L V Thang; M M Galano; E Babu; Vadivel Ganapathy; T Kanazawa; Jonathan B McHugh; Thomas Carey
Isoforms, expression, glycosylation, and tissue distribution of CTL2/SLC44A2.
The protein journal 2010;29(6):417-26.
2010: Helen M Becker; Nilufar Mohebbi; Angelica Perna; Vadivel Ganapathy; Giovambattista Capasso; Carsten A Wagner
Localization of members of MCT monocarboxylate transporter family Slc16 in the kidney and regulation during metabolic acidosis.
American journal of physiology. Renal physiology 2010;299(1):F141-54.
2010: I-K Kwon; R Wang; Muthusamy Thangaraju; H Shuang; Kebin Liu; Roderick H Dashwood; Nickolai O Dulin; Vadivel Ganapathy; Darren Browning
PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4.
Oncogene 2010;29(23):3423-34.
2010: Maciej P Mazurek; Puttur D Prasad; Elangovan Gopal; Scott P Fraser; Leszek Bolt; Nahit Rizaner; Christopher P Palmer; Christopher S Foster; Ferdinando Palmieri; Vadivel Ganapathy; Walter Stühmer; Mustafa B A Djamgoz; Maria E Mycielska
Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells.
EMBO reports 2010;11(6):431-7.
2010: Seiji Miyauchi; Elangovan Gopal; Ellappan Babu; Sonne R Srinivas; Yoshiyuki Kubo; Umapathy Siddaramappa; Santoshanand V Thakkar; Vadivel Ganapathy; Puttur D Prasad
Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.
Biochimica et biophysica acta 2010;1798(6):1164-71.
2010: B Renee Bozard; Preethi S Ganapathy; Jennifer Duplantier; Barbara Mysona; Yonju Ha; Penny Roon; Robert Smith; I David Goldman; Puttur D Prasad; Pamela Moore Martin; Vadivel Ganapathy; Sylvia B Smith
Molecular and biochemical characterization of folate transport proteins in retinal Müller cells.
Investigative ophthalmology & visual science 2010;51(6):3226-35.
2010: Jaya P Gnana-Prakasam; Pamela Moore Martin; Sylvia B Smith; Vadivel Ganapathy
Expression and function of iron-regulatory proteins in retina.
IUBMB life 2010;62(5):363-70.
2010: Sudha Ananth; Lina Zhuang; Elangovan Gopal; Shiro Itagaki; Babu Ellappan; Sylvia B Smith; Vadivel Ganapathy; Pamela Moore Martin
Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: a RPE specific phenomenon.
Biochemical and biophysical research communications 2010;394(1):75-80.
2010: Gail A Cresci; Muthusamy Thangaraju; John D Mellinger; Kebin Liu; Vadivel Ganapathy
Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2010;14(3):449-61.
2010: Mary Zimmerman; Dafeng Yang; Xiaolin Hu; Feiyan Liu; Nagendra Singh; Darren Browning; Vadivel Ganapathy; Phillip R Chandler; Divaker Choubey; Scott I Abrams; Kebin Liu
IFN-γ upregulates survivin and Ifi202 expression to induce survival and proliferation of tumor-specific T cells.
PloS one 2010;5(11):e14076.
2010: Sudharsan Periyasamy-Thandavan; William H Jackson; Julia S Samaddar; Brian Erickson; John R Barrett; Lauren Raney; Elangovan Gopal; Vadivel Ganapathy; William Hill; Kapil N Bhalla; Patricia V Schoenlein
Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress and induces caspase-dependent cell death in antiestrogen-sensitive and resistant ER+ breast cancer cells.
Autophagy 2010;6(1):19-35.
2010: Catriona M H Anderson; Mark Jevons; Muthusamy Thangaraju; Noel Edwards; Nichola J Conlon; Steven Woods; Vadivel Ganapathy; David T Thwaites
Transport of the photodynamic therapy agent 5-aminolevulinic acid by distinct H+-coupled nutrient carriers coexpressed in the small intestine.
The Journal of pharmacology and experimental therapeutics 2010;332(1):220-8.
2010: Paresh P Chothe; Santoshanand V Thakkar; Jaya P Gnana-Prakasam; Sudha Ananth; David R Hinton; Ram Kannan; Sylvia B Smith; Pamela Moore Martin; Vadivel Ganapathy
Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2010;51(1):413-20.
2009: Jaya P Gnana-Prakasam; Muthusamy Thangaraju; Kebin Liu; Yonju Ha; Pamela Moore Martin; Sylvia B Smith; Vadivel Ganapathy
Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger.
The Biochemical journal 2009;424(2):243-52.
2009: Muthusamy Thangaraju; Senthil K Karunakaran; Shiro Itagaki; Elangovan Gopal; Selvakumar Elangovan; Puttur D Prasad; Vadivel Ganapathy
Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate.
Cancer 2009;115(20):4655-66.
2009: Masanori Tachikawa; Yasuyuki Kasai; Reiji Yokoyama; Jun Fujinawa; Vadivel Ganapathy; Tetsuya Terasaki; Ken-ichi Hosoya
The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters.
Journal of neurochemistry 2009;111(2):499-509.
2009: Jaya P Gnana-Prakasam; Ming Zhang; Pamela Moore Martin; Sally Atherton; Sylvia B Smith; Vadivel Ganapathy
Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection.
The Biochemical journal 2009;419(3):533-43.
2009: Sudha Ananth; Senthil Karunakaran; Pamela Moore Martin; Chandrasekharam N Nagineni; John J Hooks; Sylvia B Smith; Puttur D Prasad; Vadivel Ganapathy
Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE.
Pharmaceutical research 2009;26(5):1226-35.
2009: Muthusamy Thangaraju; Gail A Cresci; Kebin Liu; Sudha Ananth; Jaya P Gnanaprakasam; Darren Browning; John D Mellinger; Sylvia B Smith; Gregory J Digby; Nevin A Lambert; Puttur D Prasad; Vadivel Ganapathy
GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.
Cancer research 2009;69(7):2826-32.
2009: Barbara Mysona; Ying Dun; Jennifer Duplantier; Vadivel Ganapathy; Sylvia B Smith
Effects of hyperglycemia and oxidative stress on the glutamate transporters GLAST and system xc- in mouse retinal Müller glial cells.
Cell and tissue research 2009;335(3):477-88.
2009: Catriona M H Anderson; Alison Howard; Julian R F Walters; Vadivel Ganapathy; David T Thwaites
Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl(-)-dependent TauT (SLC6A6).
The Journal of physiology 2009;587(Pt 4):731-44.
2009: Rengasamy R M Maran; Ann Thomas; Megan Roth; Zhonghua Sheng; Noriko Esterly; David M Pinson; Xin Gao; Yawei Zhang; Vadivel Ganapathy; Frank J Gonzalez; Grace L Guo
Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development.
The Journal of pharmacology and experimental therapeutics 2009;328(2):469-77.
2009: Hitoshi Kashiwagi; Kojiro Yamazaki; Yoh Takekuma; Vadivel Ganapathy; Mitsuru Sugawara
Regulatory mechanisms of SNAT2, an amino acid transporter, in L6 rat skeletal muscle cells by insulin, osmotic shock and amino acid deprivation.
Amino acids 2009;36(2):219-30.
2009: Vadivel Ganapathy
A traffic signal for heterodimeric amino acid transporters to transfer from the ER to the Golgi.
The Biochemical journal 2009;417(2):e9-11.
2009: Pamela Moore Martin; Sudha Ananth; Gail A Cresci; Penny Roon; Sylvia B Smith; Vadivel Ganapathy
Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium.
Molecular vision 2009;15():362-72.
2009: Maria E Mycielska; Ameet Patel; Nahit Rizaner; Maciej P Mazurek; Hector Keun; Anup Patel; Vadivel Ganapathy; Mustafa B A Djamgoz
Citrate transport and metabolism in mammalian cells: prostate epithelial cells and prostate cancer.
BioEssays : news and reviews in molecular, cellular and developmental biology 2009;31(1):10-20.
2009: Vadivel Ganapathy; Muthusamy Thangaraju; Puttur D Prasad
Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond.
Pharmacology & therapeutics 2009;121(1):29-40.
2009: Muthusamy Thangaraju; Kristina N Carswell; Puttur D Prasad; Vadivel Ganapathy
Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.
The Biochemical journal 2009;417(1):379-89.
2008: Umapathy Siddaramappa; Ying Dun; Pamela Moore Martin; Jennifer N Duplantier; Penny Roon; Puttur D Prasad; Sylvia B Smith; Vadivel Ganapathy
Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells.
Investigative ophthalmology & visual science 2008;49(11):5151-60.
2008: Muthusamy Thangaraju; Gail A Cresci; Shiro Itagaki; John D Mellinger; Darren Browning; Franklin G Berger; Puttur D Prasad; Vadivel Ganapathy
Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2008;12(10):1773-81; discussion 1781-2.
2008: Senthil Karunakaran; Umapathy Siddaramappa; Muthusamy Thangaraju; Takahiro Hatanaka; Shirou Itagaki; David H Munn; Puttur D Prasad; Vadivel Ganapathy
Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy.
The Biochemical journal 2008;414(3):343-55.
2008: Catriona M H Anderson; Vadivel Ganapathy; David T Thwaites
Human solute carrier SLC6A14 is the beta-alanine carrier.
The Journal of physiology 2008;586(Pt 17):4061-7.
2008: Sylvia B Smith; Jennifer Duplantier; Ying Dun; Barbara Mysona; Penny Roon; Pamela Moore Martin; Vadivel Ganapathy
In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine.
Investigative ophthalmology & visual science 2008;49(9):4154-61.
2008: Jamilur R Talukder; Ramesh Kekuda; prosenjit saha; Puttur D Prasad; Vadivel Ganapathy; Uma Sundaram
Functional characterization, localization, and molecular identification of rabbit intestinal N-amino acid transporter.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(6):G1301-10.
2008: David J Kozlowski; Zhong Chen; Lina Zhuang; You-Jun Fei; Sammy Navarre; Vadivel Ganapathy
Molecular characterization and expression pattern of taurine transporter in zebrafish during embryogenesis.
Life sciences 2008;82(19-20):1004-11.
2008: In-Kiu Kwon; Patricia V Schoenlein; Jennifer Delk; Kebin Liu; Muthusamy Thangaraju; Nickolai O Dulin; Vadivel Ganapathy; Franklin G Berger; Darren Browning
Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis.
Cancer 2008;112(7):1462-70.
2008: Linda Metzner; Kristin Natho; Katja Zebisch; Madlen Dorn; Eva Bosse-Doenecke; Vadivel Ganapathy; Matthias Brandsch
Mutational analysis of histidine residues in the human proton-coupled amino acid transporter PAT1.
Biochimica et biophysica acta 2008;1778(4):1042-50.
2008: Jaya P Gnana-Prakasam; Pamela Moore Martin; Barbara A Mysona; Penny Roon; Sylvia B Smith; Vadivel Ganapathy
Hepcidin expression in mouse retina and its regulation via lipopolysaccharide/Toll-like receptor-4 pathway independent of Hfe.
The Biochemical journal 2008;411(1):79-88.
2008: Winnie Deuther-Conrad; Jörg Thomas Patt; Paul R Lockman; D D Allen; Marianne Patt; Andreas Schildan; Vadivel Ganapathy; Jörg Steinbach; Osama Sabri; Peter Brust
Norchloro-fluoro-homoepibatidine (NCFHEB) - a promising radioligand for neuroimaging nicotinic acetylcholine receptors with PET.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2008;18(3):222-9.
2008: Ying Dun; Jennifer Duplantier; Penny Roon; Pamela Moore Martin; Vadivel Ganapathy; Sylvia B Smith
Serine racemase expression and D-serine content are developmentally regulated in neuronal ganglion cells of the retina.
Journal of neurochemistry 2008;104(4):970-8.
2008: Santoshanand V Thakkar; Seiji Miyauchi; Puttur D Prasad; Vadivel Ganapathy
Stimulation of Na+/Cl--coupled opioid peptide transport system in SK-N-SH cells by L-kyotorphin, an endogenous substrate for H+-coupled peptide transporter PEPT2.
Drug metabolism and pharmacokinetics 2008;23(4):254-62.
2008: Vadivel Ganapathy; Muthusamy Thangaraju; Elangovan Gopal; Pamela Moore Martin; Shirou Itagaki; Seiji Miyauchi; Puttur D Prasad
Sodium-coupled monocarboxylate transporters in normal tissues and in cancer.
The AAPS journal 2008;10(1):193-9.
2007: Prem S Shekhawat; Sonne R Srinivas; Dietrich Matern; Michael J Bennett; Richard Boriack; Varghese George; Hongyan Xu; Puttur D Prasad; Penny Roon; Vadivel Ganapathy
Spontaneous development of intestinal and colonic atrophy and inflammation in the carnitine-deficient jvs (OCTN2(-/-)) mice.
Molecular genetics and metabolism 2007;92(4):315-24.
2007: Umapathy Siddaramappa; Jaya P Gnana-Prakasam; Pamela Moore Martin; Barbara Mysona; Ying Dun; Sylvia B Smith; Vadivel Ganapathy; Puttur D Prasad
Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types.
Investigative ophthalmology & visual science 2007;48(11):5299-305.
2007: Sonne R Srinivas; Puttur D Prasad; Umapathy Siddaramappa; Vadivel Ganapathy; Prem S Shekhawat
Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+).
American journal of physiology. Gastrointestinal and liver physiology 2007;293(5):G1046-53.
2007: Elangovan Gopal; Umapathy Siddaramappa; Pamela Moore Martin; Sudha Ananth; Jaya P Gnana-Prakasam; H Becker; Carsten A Wagner; Vadivel Ganapathy; Puttur D Prasad
Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney.
Biochimica et biophysica acta 2007;1768(11):2690-7.
2007: Ying Dun; Muthusamy Thangaraju; Puttur D Prasad; Vadivel Ganapathy; Sylvia B Smith
Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligand.
Investigative ophthalmology & visual science 2007;48(10):4785-94.
2007: Dafeng Yang; Muthusamy Thangaraju; Darren Browning; Zheng Dong; Borys Korchin; Dina C Lev; Vadivel Ganapathy; Kebin Liu
IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(7):4775-82.
2007: B Baisden; S Sonne; Ratan Mani Joshi; Vadivel Ganapathy; Prem S Shekhawat
Antenatal dexamethasone treatment leads to changes in gene expression in a murine late placenta.
Placenta 2007;28(10):1082-90.
2007: Patricia V Schoenlein; Min Hou; Julia S Samaddar; Virgil T Gaddy; Muthusamy Thangaraju; Jill E Lewis; Maribeth H Johnson; Vadivel Ganapathy; Andre M Kallab; John T Barrett
Downregulation of retinoblastoma protein is involved in the enhanced cytotoxicity of 4-hydroxytamoxifen plus mifepristone combination therapy versus antiestrogen monotherapy of human breast cancer.
International journal of oncology 2007;31(3):643-55.
2007: Pamela Moore Martin; Ying Dun; Barbara Mysona; Sudha Ananth; Penny Roon; Sylvia B Smith; Vadivel Ganapathy
Expression of the sodium-coupled monocarboxylate transporters SMCT1 (SLC5A8) and SMCT2 (SLC5A12) in retina.
Investigative ophthalmology & visual science 2007;48(7):3356-63.
2007: Victoria Makrides; Reinhard Bauer; Wolfgang Weber; Hans-Jürgen Wester; Steffen Fischer; Rainer Hinz; Katja Huggel; Thomas Opfermann; Michael Herzau; Vadivel Ganapathy; François Verrey; Peter Brust
Preferred transport of O-(2-[18F]fluoroethyl)-D-tyrosine (D-FET) into the porcine brain.
Brain research 2007;1147():25-33.
2007: Dafeng Yang; Muthusamy Thangaraju; Kristy M Greeneltch; Darren Browning; Patricia V Schoenlein; Tomohiko Tamura; Keiko Ozato; Vadivel Ganapathy; Scott I Abrams; Kebin Liu
Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells.
Cancer research 2007;67(7):3301-9.
2007: Seiji Miyauchi; Elangovan Gopal; Santosh V Thakkar; Satoshi Ichikawa; Puttur D Prasad; Vadivel Ganapathy
Differential modulation of sodium- and chloride-dependent opioid peptide transport system by small nonopioid peptides and free amino acids.
The Journal of pharmacology and experimental therapeutics 2007;321(1):257-64.
2007: Akiteru Seki; Seiji Miyauchi; Saori Hayashi; Takashi Kikukawa; Megumi Kubo; Makoto Demura; Vadivel Ganapathy; Naoki Kamo
Heterologous expression of Pharaonis halorhodopsin in Xenopus laevis oocytes and electrophysiological characterization of its light-driven Cl- pump activity.
Biophysical journal 2007;92(7):2559-69.
2007: Elangovan Gopal; Seiji Miyauchi; Pamela Moore Martin; Sudha Ananth; Penny Roon; Sylvia B Smith; Vadivel Ganapathy
Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract.
Pharmaceutical research 2007;24(3):575-84.
2007: Yoh Takekuma; Haruka Kakiuchi; Koujiro Yamazaki; Seiji Miyauchi; Takashi Kikukawa; Naoki Kamo; Vadivel Ganapathy; Mitsuru Sugawara
Difference between pharmacokinetics of mycophenolic acid (MPA) in rats and that in humans is caused by different affinities of MRP2 to a glucuronized form.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2007;10(1):71-85.
2007: A A Howlett; Timothy L Mailman; Vadivel Ganapathy
Early cystic lung disease in a premature neonate with perinatally acquired capnocytophaga.
Journal of perinatology : official journal of the California Perinatal Association 2007;27(1):68-70.
2007: Ying Dun; Barbara Mysona; S Itagaki; Angeline Martin-Studdard; Vadivel Ganapathy; Sylvia B Smith
Functional and molecular analysis of D-serine transport in retinal Müller cells.
Experimental eye research 2007;84(1):191-9.
2007: Elangovan Gopal; Seiji Miyauchi; Pamela Moore Martin; Sudha Ananth; Sonne R Srinivas; Sylvia B Smith; Puttur D Prasad; Vadivel Ganapathy
Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(1):G402-8.
2006: Takahiro Hatanaka; Yasue Hatanaka; Jun-Ichi Tsuchida; Vadivel Ganapathy; Mitsutoshi Setou
Amino acid transporter ATA2 is stored at the trans-Golgi network and released by insulin stimulus in adipocytes.
The Journal of biological chemistry 2006;281(51):39273-84.
2006: Muthusamy Thangaraju; Elangovan Gopal; Pamela Moore Martin; Sudha Ananth; Sylvia B Smith; Puttur D Prasad; Esta Sterneck; Vadivel Ganapathy
SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases.
Cancer research 2006;66(24):11560-4.
2006: Guoliang Jiang; Barbara Mysona; Ying Dun; Jaya P Gnana-Prakasam; Navjotsin Pabla; Weiguo Li; Zheng Dong; Vadivel Ganapathy; Sylvia B Smith
Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells.
Investigative ophthalmology & visual science 2006;47(12):5576-82.
2006: Robert L Seymour; Vadivel Ganapathy; Andrew L Mellor; David H Munn
A high-affinity, tryptophan-selective amino acid transport system in human macrophages.
Journal of leukocyte biology 2006;80(6):1320-7.
2006: Nina Jansson; Jessica Pettersson; Allah Haafiz; Anette Ericsson; Isabelle Palmberg; Mattias Tranberg; Vadivel Ganapathy; Theresa Powell; Thomas B. Jansson
Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet.
The Journal of physiology 2006;576(Pt 3):935-46.
2006: Pamela Moore Martin; Jaya P Gnana-Prakasam; Penny Roon; Robert G Smith; Sylvia B Smith; Vadivel Ganapathy
Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium.
Investigative ophthalmology & visual science 2006;47(10):4238-44.
2006: Muthusamy Thangaraju; Sudha Ananth; Pamela Moore Martin; Penny Roon; Sylvia B Smith; Esta Sterneck; Puttur D Prasad; Vadivel Ganapathy
c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney.
The Journal of biological chemistry 2006;281(37):26769-73.
2006: Yali Hou; Naren Gupta; Patricia V Schoenlein; Elsie Wong; Robert G Martindale; Vadivel Ganapathy; Darren Browning
An anti-tumor role for cGMP-dependent protein kinase.
Cancer letters 2006;240(1):60-8.
2006: Fiona E Baird; Jorge J Pinilla-Tenas; William L J Ogilvie; Vadivel Ganapathy; Harinder S Hundal; Peter M Taylor
Evidence for allosteric regulation of pH-sensitive System A (SNAT2) and System N (SNAT5) amino acid transporter activity involving a conserved histidine residue.
The Biochemical journal 2006;397(2):369-75.
2006: Pamela Moore Martin; Elangovan Gopal; Sudha Ananth; Lina Zhuang; Shirou Itagaki; Balakrishna M Prasad; Sylvia B Smith; Puttur D Prasad; Vadivel Ganapathy
Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of L-lactate and ketone bodies in the brain.
Journal of neurochemistry 2006;98(1):279-88.
2006: Shirou Itagaki; Elangovan Gopal; Lina Zhuang; You-Jun Fei; Seiji Miyauchi; Puttur D Prasad; Vadivel Ganapathy
Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8).
Pharmaceutical research 2006;23(6):1209-16.
2006: Seiji Miyauchi; Sonne R Srinivas; You-Jun Fei; Elangovan Gopal; Umapathy Siddaramappa; Heng Wang; S J Conway; Vadivel Ganapathy; Puttur D Prasad
Functional characteristics of NaS2, a placenta-specific Na+-coupled transporter for sulfate and oxyanions of the micronutrients selenium and chromium.
Placenta 2006;27(6-7):550-9.
2006: Naren Gupta; Pamela Moore Martin; Seiji Miyauchi; Sudha Ananth; Anne V Herdman; Robert G Martindale; Robert Podolsky; Vadivel Ganapathy
Down-regulation of BCRP/ABCG2 in colorectal and cervical cancer.
Biochemical and biophysical research communications 2006;343(2):571-7.
2006: Ying Dun; Barbara Mysona; Tracy K Van Ells; L Amarnath; M Shamsul Ola; Vadivel Ganapathy; Sylvia B Smith
Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stress.
Cell and tissue research 2006;324(2):189-202.
2006: Huankai Hu; Christopher J Endres; Cheng Chang; Umapathy Siddaramappa; Eun-Woo Lee; You-Jun Fei; Shirou Itagaki; Peter Swaan; Vadivel Ganapathy; Jashvant D Unadkat
Electrophysiological characterization and modeling of the structure activity relationship of the human concentrative nucleoside transporter 3 (hCNT3).
Molecular pharmacology 2006;69(5):1542-53.
2006: Naren Gupta; Pamela Moore Martin; Puttur D Prasad; Vadivel Ganapathy
SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter.
Life sciences 2006;78(21):2419-25.
2006: Etsuo Yodoya; Miyuki Wada; Ayumi Shimada; Hiromi Katsukawa; Naoki Okada; Akira Yamamoto; Vadivel Ganapathy; Takuya Fujita
Functional and molecular identification of sodium-coupled dicarboxylate transporters in rat primary cultured cerebrocortical astrocytes and neurons.
Journal of neurochemistry 2006;97(1):162-73.
2006: Vadivel Ganapathy; Takuya Fujita
Identity of the high-affinity sodium/carboxylate cotransporter NaC3 as the N-acetyl-L-aspartate transporter.
Advances in experimental medicine and biology 2006;576():67-76; discussion 361-3.
2006: Vadivel Ganapathy; You-Jun Fei; Puttur D Prasad
Heterologous expression systems for studying placental transporters.
Methods in molecular medicine 2006;122():285-300.
2006: Naren Gupta; Puttur D Prasad; Sharad A Ghamande; Pamela Moore-Martin; Anne V Herdman; Robert G Martindale; Robert Podolsky; Sela Mager; Malliga E Ganapathy; Vadivel Ganapathy
Up-regulation of the amino acid transporter ATB(0,+) (SLC6A14) in carcinoma of the cervix.
Gynecologic oncology 2006;100(1):8-13.
2005: Sonne R Srinivas; Elangovan Gopal; Lina Zhuang; Shirou Itagaki; Pamela Moore Martin; You-Jun Fei; Vadivel Ganapathy; Puttur D Prasad
Cloning and functional identification of slc5a12 as a sodium-coupled low-affinity transporter for monocarboxylates (SMCT2).
The Biochemical journal 2005;392(Pt 3):655-64.
2005: Malliga E Ganapathy; Vadivel Ganapathy
Amino Acid Transporter ATB0,+ as a delivery system for drugs and prodrugs.
Current drug targets. Immune, endocrine and metabolic disorders 2005;5(4):357-64.
2005: Seiji Miyauchi; Emily L Abbot; Lina Zhuang; Radhika Subramanian; Vadivel Ganapathy; David T Thwaites
Isolation and function of the amino acid transporter PAT1 (slc36a1) from rabbit and discrimination between transport via PAT1 and system IMINO in renal brush-border membrane vesicles.
Molecular membrane biology 2005;22(6):549-59.
2005: Umapathy Siddaramappa; Weiguo Li; Barbara Mysona; Sylvia B Smith; Vadivel Ganapathy
Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells.
Investigative ophthalmology & visual science 2005;46(11):3980-7.
2005: Boonrit Thongsong; Radhika K Subramanian; Vadivel Ganapathy; Puttur D Prasad
Inhibition of amino acid transport system a by interleukin-1beta in trophoblasts.
Journal of the Society for Gynecologic Investigation 2005;12(7):495-503.
2005: Vadivel Ganapathy; Puttur D Prasad
Role of transporters in placental transfer of drugs.
Toxicology and applied pharmacology 2005;207(2 Suppl):381-7.
2005: Naren Gupta; Seiji Miyauchi; Robert G Martindale; Anne V Herdman; Robert Podolsky; Katsuya Miyake; Sela Mager; Puttur D Prasad; Malliga E Ganapathy; Vadivel Ganapathy
Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans.
Biochimica et biophysica acta 2005;1741(1-2):215-23.
2005: Elangovan Gopal; You-Jun Fei; Seiji Miyauchi; Lina Zhuang; Puttur D Prasad; Vadivel Ganapathy
Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family.
The Biochemical journal 2005;388(Pt 1):309-16.
2005: Takuya Fujita; Hiromi Katsukawa; Etsuo Yodoya; Miyuki Wada; Ayumi Shimada; Naoki Okada; Akira Yamamoto; Vadivel Ganapathy
Transport characteristics of N-acetyl-L-aspartate in rat astrocytes: involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system.
Journal of neurochemistry 2005;93(3):706-14.
2005: Pascaline Gaildrat; Morten Møller; Sujira Mukda; Ann Humphries; David A Carter; Vadivel Ganapathy; David Klein
A novel pineal-specific product of the oligopeptide transporter PepT1 gene: circadian expression mediated by cAMP activation of an intronic promoter.
The Journal of biological chemistry 2005;280(17):16851-60.
2005: Vadivel Ganapathy; Elangovan Gopal; Seiji Miyauchi; Puttur D Prasad
Biological functions of SLC5A8, a candidate tumour suppressor.
Biochemical Society transactions 2005;33(Pt 1):237-40.
2005: Guoliang Jiang; Lina Zhuang; Seiji Miyauchi; Katsuya Miyake; You-Jun Fei; Vadivel Ganapathy
A Na+/Cl- -coupled GABA transporter, GAT-1, from Caenorhabditis elegans: structural and functional features, specific expression in GABA-ergic neurons, and involvement in muscle function.
The Journal of biological chemistry 2005;280(3):2065-77.
2005: Vadivel Ganapathy; Seiji Miyauchi
Transport systems for opioid peptides in mammalian tissues.
The AAPS journal 2005;7(4):E852-6.
2005: Hany Naggar; Tracy K Van Ells; Vadivel Ganapathy; Sylvia B Smith
Regulation of reduced-folate transporter-1 in retinal pigment epithelial cells by folate.
Current eye research 2005;30(1):35-44.
2005: David J Kennedy; Kelly M Gatfield; John P Winpenny; Vadivel Ganapathy; David T Thwaites
Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2).
British journal of pharmacology 2005;144(1):28-41.
2005: Birgit Alteheld; Mary E Evans; Li H Gu; Vadivel Ganapathy; F H Leibach; Dean P Jones; Thomas R Ziegler
Alanylglutamine dipeptide and growth hormone maintain PepT1-mediated transport in oxidatively stressed Caco-2 cells.
The Journal of nutrition 2005;135(1):19-26.
2004: Pushpa V Thadani; Jerome F Strauss; Sudhansu K Dey; Virginia M Anderson; Kenneth L Audus; Karen S Coats; James C Cross; Adrian Erlebacher; Vadivel Ganapathy; Daniel I Linzer; Richard Miller; Donald A Novak; Rao S Rapaka; Yoel Sadovsky; Carolyn M Salafia; Michael Soares; Jashvant Unadkat
National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development.
American journal of obstetrics and gynecology 2004;191(6):1858-62.
2004: Catriona M H Anderson; Danielle S Grenade; Michael Boll; Martin Foltz; Katherine A Wake; David J Kennedy; Lars K Munck; Seiji Miyauchi; Peter M Taylor; Frederick Charles Campbell; Bjarne G Munck; Hannelore Daniel; Vadivel Ganapathy; David T Thwaites
H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat.
Gastroenterology 2004;127(5):1410-22.
2004: Elangovan Gopal; You-Jun Fei; Mitsuru Sugawara; Seiji Miyauchi; Lina Zhuang; Pamela Moore Martin; Sylvia B Smith; Puttur D Prasad; Vadivel Ganapathy
Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate.
The Journal of biological chemistry 2004;279(43):44522-32.
2004: Peter Brust; Gerd Vorwieger; Bernd Walter; Frank Füchtner; Holger Stark; Hiroto Kuwabara; Michael Herzau; Thomas Opfermann; Jörg Steinbach; Vadivel Ganapathy; Reinhard Bauer
The influx of neutral amino acids into the porcine brain during development: a positron emission tomography study.
Brain research. Developmental brain research 2004;152(2):241-53.
2004: Ronald L George; Wei Huang; Hany A Naggar; Sylvia B Smith; Vadivel Ganapathy
Transport of N-acetylaspartate via murine sodium/dicarboxylate cotransporter NaDC3 and expression of this transporter and aspartoacylase II in ocular tissues in mouse.
Biochimica et biophysica acta 2004;1690(1):63-9.
2004: Blisse Jain-Vakkalagadda; Dhananjay Pal; Sriram Gunda; Yasser E Nashed; Vadivel Ganapathy; Laura jane Jolliffe
Identification of a Na+-dependent cationic and neutral amino acid transporter, B(0,+), in human and rabbit cornea.
Molecular pharmaceutics 2004;1(5):338-46.
2004: Pamela Moore Martin; Penny Roon; Tracy K Van Ells; Vadivel Ganapathy; Sylvia B Smith
Death of retinal neurons in streptozotocin-induced diabetic mice.
Investigative ophthalmology & visual science 2004;45(9):3330-6.
2004: Christy Bridges; Huankai Hu; Seiji Miyauchi; Umapathy Siddaramappa; Malliga E Ganapathy; Leszek Ignatowicz; Dennis M Maddox; Sylvia B Smith; Vadivel Ganapathy
Induction of cystine-glutamate transporter xc- by human immunodeficiency virus type 1 transactivator protein tat in retinal pigment epithelium.
Investigative ophthalmology & visual science 2004;45(9):2906-14.
2004: Prem S Shekhawat; Han-Soo Yang; Michael J Bennett; Alva Lee Carter; Dietrich Matern; Ikumi Tamai; Vadivel Ganapathy
Carnitine content and expression of mitochondrial beta-oxidation enzymes in placentas of wild-type (OCTN2(+/+)) and OCTN2 Null (OCTN2(-/-)) Mice.
Pediatric research 2004;56(3):323-8.
2004: Fiona E Baird; K J Beattie; A R Hyde; Vadivel Ganapathy; Michael John Rennie; Peter M Taylor
Bidirectional substrate fluxes through the system N (SNAT5) glutamine transporter may determine net glutamine flux in rat liver.
The Journal of physiology 2004;559(Pt 2):367-81.
2004: Umapathy Siddaramappa; Vadivel Ganapathy; Malliga E Ganapathy
Transport of amino acid esters and the amino-acid-based prodrug valganciclovir by the amino acid transporter ATB(0,+).
Pharmaceutical research 2004;21(7):1303-10.
2004: Zhong Chen; Wei Huang; Sonne R Srinivas; Chandra R Jones; Vadivel Ganapathy; Puttur D Prasad
Serine racemase and D-serine transport in human placenta and evidence for a transplacental gradient for D-serine in humans.
Journal of the Society for Gynecologic Investigation 2004;11(5):294-303.
2004: Pamela Moore Martin; M Shamsul Ola; Neeraj Agarwal; Vadivel Ganapathy; Sylvia B Smith
The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate.
Brain research. Molecular brain research 2004;123(1-2):66-75.
2004: Seiji Miyauchi; Elangovan Gopal; You-Jun Fei; Vadivel Ganapathy
Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids.
The Journal of biological chemistry 2004;279(14):13293-6.
2004: You-Jun Fei; Jin-Cai Liu; Katsuhisa Inoue; Lina Zhuang; Katsuya Miyake; Seiji Miyauchi; Vadivel Ganapathy
Relevance of NAC-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans.
The Biochemical journal 2004;379(Pt 1):191-8.
2004: Katsuhisa Inoue; You-Jun Fei; Lina Zhuang; Elangovan Gopal; Seiji Miyauchi; Vadivel Ganapathy
Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates.
The Biochemical journal 2004;378(Pt 3):949-57.
2004: Takahiro Hatanaka; Masayuki Haramura; You-Jun Fei; Seiji Miyauchi; Christy Bridges; Preethi S Ganapathy; Sylvia B Smith; Vadivel Ganapathy; Malliga E Ganapathy
Transport of amino acid-based prodrugs by the Na+- and Cl(-) -coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery.
The Journal of pharmacology and experimental therapeutics 2004;308(3):1138-47.
2004: Vadivel Ganapathy; Sylvia B Smith; Puttur D Prasad
SLC19: the folate/thiamine transporter family.
Pflügers Archiv : European journal of physiology 2004;447(5):641-6.
2004: Amira El-Sherbeny; Hany Naggar; Seiji Miyauchi; M Shamsul Ola; Dennis M Maddox; Pamela Moore Martin; Vadivel Ganapathy; Sylvia B Smith
Osmoregulation of taurine transporter function and expression in retinal pigment epithelial, ganglion, and müller cells.
Investigative ophthalmology & visual science 2004;45(2):694-701.
2004: Takuya Fujita; Takeshi Kishida; Miyuki Wada; Naoki Okada; Akira Yamamoto; Frederick H Leibach; Vadivel Ganapathy
Functional characterization of brain peptide transporter in rat cerebral cortex: identification of the high-affinity type H+/peptide transporter PEPT2.
Brain research 2004;997(1):52-61.
2003: Hany Naggar; You-Jun Fei; Vadivel Ganapathy; Sylvia B Smith
Regulation of reduced-folate transporter-1 (RFT-1) by homocysteine and identity of transport systems for homocysteine uptake in retinal pigment epithelial (RPE) cells.
Experimental eye research 2003;77(6):687-97.
2003: Huankai Hu; Seiji Miyauchi; Christy Bridges; Sylvia B Smith; Vadivel Ganapathy
Identification of a novel Na+- and Cl--coupled transport system for endogenous opioid peptides in retinal pigment epithelium and induction of the transport system by HIV-1 Tat.
The Biochemical journal 2003;375(Pt 1):17-22.
2003: Katsuhisa Inoue; Lina Zhuang; Dennis M Maddox; Sylvia B Smith; Vadivel Ganapathy
Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action.
The Biochemical journal 2003;374(Pt 1):21-6.
2003: Dennis M Maddox; Anna Manlapat; Penny Roon; Puttur D Prasad; Vadivel Ganapathy; Sylvia B Smith
Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart.
BMC developmental biology 2003;3():6.
2003: Surajit Dey; Jignesh Patel; Banmeet S Anand; Blisse Jain-Vakkalagadda; Preetham Kaliki; Dhananjay Pal; Vadivel Ganapathy; Laura jane Jolliffe
Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines.
Investigative ophthalmology & visual science 2003;44(7):2909-18.
2003: Zhong Chen; David J Kennedy; Katherine A Wake; Lina Zhuang; Vadivel Ganapathy; David T Thwaites
Structure, tissue expression pattern, and function of the amino acid transporter rat PAT2.
Biochemical and biophysical research communications 2003;304(4):747-54.
2003: Anne Friedrich; Puttur D Prasad; Dorette Freyer; Vadivel Ganapathy; Peter Brust
Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood-brain barrier.
Brain research 2003;968(1):69-79.
2003: Puttur D Prasad; Vadivel Ganapathy
Keratinocytes join forces with immune cells in the prosecution of SMVT as a "false" biotin transporter.
The Journal of investigative dermatology 2003;120(3):xi-xii.
2003: You-Jun Fei; Katsuhisa Inoue; Vadivel Ganapathy
Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span.
The Journal of biological chemistry 2003;278(8):6136-44.
2003: D Michael Nelson; Steven D Smith; TC Furesz; Yoel Sadovsky; Vadivel Ganapathy; C A Parvin; Carl H Smith
Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts.
American journal of physiology. Cell physiology 2003;284(2):C310-5.
2003: Zhong Chen; You-Jun Fei; Catriona M H Anderson; Katherine A Wake; Seiji Miyauchi; Wei Huang; David T Thwaites; Vadivel Ganapathy
Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2.
The Journal of physiology 2003;546(Pt 2):349-61.
2003: Mitsuru Sugawara; Masaya Kato; Mayumi Kitakubo; Yoh Takekuma; Vadivel Ganapathy; Katsumi Miyazaki
Inhibitory effects of basic drugs on the sodium-dependent transport of L-alanine via system B0 in the small intestine.
Drug metabolism and pharmacokinetics 2003;18(3):186-93.
2003: Jeffrey L Rausch; Maria E Johnson; Katina M Corley; Henry M Hobby; Nitin Sudhakar Shendarkar; You-Jun Fei; Vadivel Ganapathy; Fred H Leibach
Depressed patients have higher body temperature: 5-HT transporter long promoter region effects.
Neuropsychobiology 2003;47(3):120-7.
2002: Jeffrey L Rausch; C F Gillespie; You-Jun Fei; Henry M Hobby; T Stoming; Vadivel Ganapathy; Fred H Leibach
Antidepressant effects on kinase gene expression patterns in rat brain.
Neuroscience letters 2002;334(2):91-4.
2002: Katsuhisa Inoue; Lina Zhuang; Vadivel Ganapathy
Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function.
Biochemical and biophysical research communications 2002;299(3):465-71.
2002: M Shamsul Ola; Pamela Moore; Dennis M Maddox; Amira El-Sherbeny; Wei Huang; Penny Roon; Neeraj Agarwal; Vadivel Ganapathy; Sylvia B Smith
Analysis of sigma receptor (sigmaR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice.
Brain research. Molecular brain research 2002;107(2):97-107.
2002: Katsuhisa Inoue; Lina Zhuang; Dennis M Maddox; Sylvia B Smith; Vadivel Ganapathy
Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain.
The Journal of biological chemistry 2002;277(42):39469-76.
2002: Katsuhisa Inoue; You-Jun Fei; Wei Huang; Lina Zhuang; Zhong Chen; Vadivel Ganapathy
Functional identity of Drosophila melanogaster Indy as a cation-independent, electroneutral transporter for tricarboxylic acid-cycle intermediates.
The Biochemical journal 2002;367(Pt 2):313-9.
2002: David J Kennedy; F H Leibach; Vadivel Ganapathy; David T Thwaites
Optimal absorptive transport of the dipeptide glycylsarcosine is dependent on functional Na+/H+ exchange activity.
Pflügers Archiv : European journal of physiology 2002;445(1):139-46.
2002: Chandra R Jones; Sonne R Srinivas; Lawrence D Devoe; Vadivel Ganapathy; Puttur D Prasad
Inhibition of system A amino acid transport activity by ethanol in BeWo choriocarcinoma cells.
American journal of obstetrics and gynecology 2002;187(1):209-16.
2002: Jeffrey L Rausch; Maria E Johnson; You-Jun Fei; Jun Qing Li; Nitin Sudhakar Shendarkar; Henry M Hobby; Vadivel Ganapathy; Fred H Leibach
Initial conditions of serotonin transporter kinetics and genotype: influence on SSRI treatment trial outcome.
Biological psychiatry 2002;51(9):723-32.
2002: Takahiro Hatanaka; Wei Huang; Takeo Nakanishi; Christy Bridges; Sylvia B Smith; Puttur D Prasad; Malliga E Ganapathy; Vadivel Ganapathy
Transport of D-serine via the amino acid transporter ATB(0,+) expressed in the colon.
Biochemical and biophysical research communications 2002;291(2):291-5.
2002: Christy Bridges; Amira El-Sherbeny; M Shamsul Ola; Vadivel Ganapathy; Sylvia B Smith
Transcellular transfer of folate across the retinal pigment epithelium.
Current eye research 2002;24(2):129-38.
2002: Hany Naggar; M Shamsul Ola; Pamela Moore; Wei Huang; Christy Bridges; Vadivel Ganapathy; Sylvia B Smith
Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice.
Investigative ophthalmology & visual science 2002;43(2):556-63.
2001: Christy Bridges; M Shamsul Ola; Puttur D Prasad; Amira El-Sherbeny; Vadivel Ganapathy; Sylvia B Smith
Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells.
American journal of physiology. Cell physiology 2001;281(6):C1825-36.
2001: Takeo Nakanishi; R Kekuda; You-Jun Fei; Takahiro Hatanaka; Mitsuru Sugawara; Robert G Martindale; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Cloning and functional characterization of a new subtype of the amino acid transport system N.
American journal of physiology. Cell physiology 2001;281(6):C1757-68.
2001: M Shamsul Ola; Pamela Moore; Amira El-Sherbeny; Penny Roon; Neeraj Agarwal; V P Sarthy; P Casellas; Vadivel Ganapathy; Sylvia B Smith
Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina.
Brain research. Molecular brain research 2001;95(1-2):86-95.
2001: Takahiro Hatanaka; Wei Huang; Robert G Martindale; Vadivel Ganapathy
Differential influence of cAMP on the expression of the three subtypes (ATA1, ATA2, and ATA3) of the amino acid transport system A.
FEBS letters 2001;505(2):317-20.
2001: Nelly E Avissar; Charlotte K Ryan; Vadivel Ganapathy; Harry C Sax
Na(+)-dependent neutral amino acid transporter ATB(0) is a rabbit epithelial cell brush-border protein.
American journal of physiology. Cell physiology 2001;281(3):C963-71.
2001: R Kannan; A Stolz; Q Ji; Puttur D Prasad; Vadivel Ganapathy
Vitamin C transport in human lens epithelial cells: evidence for the presence of SVCT2.
Experimental eye research 2001;73(2):159-65.
2001: P Seth; Malliga E Ganapathy; Simon J Conway; C D Bridges; Sylvia B Smith; P Casellas; Vadivel Ganapathy
Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor.
Biochimica et biophysica acta 2001;1540(1):59-67.
2001: S Ramanathan; Shahriar Pooyan; Stanley Stein; Puttur D Prasad; J Wang; Michael J Leibowitz; Vadivel Ganapathy; Patrick Sinko
Targeting the sodium-dependent multivitamin transporter (SMVT) for improving the oral absorption properties of a retro-inverso Tat nonapeptide.
Pharmaceutical research 2001;18(7):950-6.
2001: Pamela Moore; Amira El-Sherbeny; Penny Roon; Patricia V Schoenlein; Vadivel Ganapathy; Sylvia B Smith
Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine.
Experimental eye research 2001;73(1):45-57.
2001: A Friedrich; Ronald L George; Christy Bridges; Puttur D Prasad; Vadivel Ganapathy
Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4).
Biochimica et biophysica acta 2001;1512(2):299-307.
2001: R Ling; Christy Bridges; Mitsuru Sugawara; T Fujita; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A.
Biochimica et biophysica acta 2001;1512(1):15-21.
2001: Angelika Bröer; B Friedrich; Carsten A Wagner; Sophie Fillon; Vadivel Ganapathy; Florian Lang; Stefan Broer
Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains.
The Biochemical journal 2001;355(Pt 3):725-31.
2001: Takeo Nakanishi; Takahiro Hatanaka; Wei Huang; Puttur D Prasad; Fred H Leibach; Malliga E Ganapathy; Vadivel Ganapathy
Na+- and Cl--coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes.
The Journal of physiology 2001;532(Pt 2):297-304.
2001: Takahiro Hatanaka; Takeo Nakanishi; Wei Huang; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy; Malliga E Ganapathy
Na+ - and Cl- -coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B(0,+).
The Journal of clinical investigation 2001;107(8):1035-43.
2001: Christy Bridges; Amira El-Sherbeny; Penny Roon; M Shamsul Ola; R Kekuda; Vadivel Ganapathy; R S Camero; Patricia L Cameron; Sylvia B Smith
A comparison of caveolae and caveolin-1 to folate receptor alpha in retina and retinal pigment epithelium.
The Histochemical journal 2001;33(3):149-58.
2001: Nelly E Avissar; Thomas R Ziegler; Howard Wang; Li H Gu; JH Miller; P Iannoli; F H Leibach; Vadivel Ganapathy; Harry C Sax
Growth factors regulation of rabbit sodium-dependent neutral amino acid transporter ATB0 and oligopeptide transporter 1 mRNAs expression after enteretomy.
JPEN. Journal of parenteral and enteral nutrition 2001;25(2):65-72.
2001: Takeo Nakanishi; Mitsuru Sugawara; Wei Huang; Robert G Martindale; Fred H Leibach; Malliga E Ganapathy; Puttur D Prasad; Vadivel Ganapathy
Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N.
Biochemical and biophysical research communications 2001;281(5):1343-8.
2001: T Hatanaka; W Huang; R Ling; Puttur D Prasad; M Sugawara; F H Leibach; Vadivel Ganapathy
Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A.
Biochimica et biophysica acta 2001;1510(1-2):10-7.
2001: R F Gazzola; Roberto Sala; Ovidio Bussolati; Rossana Visigalli; Valeria Dall'Asta; Vadivel Ganapathy; Gian C Gazzola
The adaptive regulation of amino acid transport system A is associated to changes in ATA2 expression.
FEBS letters 2001;490(1-2):11-4.
2001: Christy Bridges; R Kekuda; Heng Wang; Puttur D Prasad; P Mehta; Wei Huang; Sylvia B Smith; Vadivel Ganapathy
Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2001;42(1):47-54.
2000: Mitsuru Sugawara; Takeo Nakanishi; You-Jun Fei; Robert G Martindale; Malliga E Ganapathy; Fred H Leibach; Vadivel Ganapathy
Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle.
Biochimica et biophysica acta 2000;1509(1-2):7-13.
2000: Wei Huang; Heng Wang; R Kekuda; You-Jun Fei; A Friedrich; J Wang; Simon J Conway; Richard S Cameron; Fred H Leibach; Vadivel Ganapathy
Transport of N-acetylaspartate by the Na(+)-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain.
The Journal of pharmacology and experimental therapeutics 2000;295(1):392-403.
2000: X Wu; Wei Huang; Malliga E Ganapathy; Heng Wang; R Kekuda; Simon J Conway; Fred H Leibach; Vadivel Ganapathy
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.
American journal of physiology. Renal physiology 2000;279(3):F449-58.
2000: You-Jun Fei; Mitsuru Sugawara; Takeo Nakanishi; Wei Huang; Heng Wang; Puttur D Prasad; Fred H Leibach; Vadivel Ganapathy
Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter.
The Journal of biological chemistry 2000;275(31):23707-17.
2000: Vadivel Ganapathy; Puttur D Prasad; Malliga E Ganapathy; Fred H Leibach
Placental transporters relevant to drug distribution across the maternal-fetal interface.
The Journal of pharmacology and experimental therapeutics 2000;294(2):413-20.
2000: Takahiro Hatanaka; Wei Huang; Heng Wang; Mitsuru Sugawara; Puttur D Prasad; Fred H Leibach; Vadivel Ganapathy
Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A.
Biochimica et biophysica acta 2000;1467(1):1-6.
2000: Heng Wang; Wei Huang; Mitsuru Sugawara; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta.
Biochemical and biophysical research communications 2000;273(3):1175-9.
2000: CD Chancy; R Kekuda; Wei Huang; Puttur D Prasad; J M Kuhnel; F M Sirotnak; Penny Roon; Vadivel Ganapathy; Sylvia B Smith
Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium.
The Journal of biological chemistry 2000;275(27):20676-84.
2000: Puttur D Prasad; Vadivel Ganapathy
Structure and function of mammalian sodium-dependent multivitamin transporter.
Current opinion in clinical nutrition and metabolic care 2000;3(4):263-6.
2000: You-Jun Fei; Mitsuru Sugawara; J C Liu; HW Li; Vadivel Ganapathy; Malliga E Ganapathy; Fred H Leibach
cDNA structure, genomic organization, and promoter analysis of the mouse intestinal peptide transporter PEPT1.
Biochimica et biophysica acta 2000;1492(1):145-54.
2000: Mitsuru Sugawara; Takeo Nakanishi; You-Jun Fei; Wei Huang; Malliga E Ganapathy; Fred H Leibach; Vadivel Ganapathy
Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A.
The Journal of biological chemistry 2000;275(22):16473-7.
2000: Vadivel Ganapathy; Tatyana Gurlo; H O Jarstadmarken; Hermann von Grafenstein
Regulation of TCR-induced IFN-gamma release from islet-reactive non-obese diabetic CD8(+) T cells by prostaglandin E(2) receptor signaling.
International immunology 2000;12(6):851-60.
2000: X Wu; Ronald L George; Wei Huang; Heng Wang; Simon J Conway; Fred H Leibach; Vadivel Ganapathy
Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta.
Biochimica et biophysica acta 2000;1466(1-2):315-27.
2000: M Sugawara; W Huang; You-Jun Fei; Fred H Leibach; Vadivel Ganapathy; Malliga E Ganapathy
Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2.
Journal of pharmaceutical sciences 2000;89(6):781-9.
2000: DP Rajan; Wei Huang; R Kekuda; Ronald L George; Jinzhao Wang; Simon J Conway; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Differential influence of the 4F2 heavy chain and the protein related to b(0,+) amino acid transport on substrate affinity of the heteromeric b(0,+) amino acid transporter.
The Journal of biological chemistry 2000;275(19):14331-5.
2000: Heng Wang; You-Jun Fei; R Kekuda; TL Yang-Feng; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Structure, function, and genomic organization of human Na(+)-dependent high-affinity dicarboxylate transporter.
American journal of physiology. Cell physiology 2000;278(5):C1019-30.
2000: Puttur D Prasad; Sonne R Srinivas; Heng Wang; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy
Electrogenic nature of rat sodium-dependent multivitamin transport.
Biochemical and biophysical research communications 2000;270(3):836-40.
2000: You-Jun Fei; M F Romero; M Krause; J C Liu; Wei Huang; Vadivel Ganapathy; Fred H Leibach
A novel H(+)-coupled oligopeptide transporter (OPT3) from Caenorhabditis elegans with a predominant function as a H(+) channel and an exclusive expression in neurons.
The Journal of biological chemistry 2000;275(13):9563-71.
2000: P D Rajan; R Kekuda; CD Chancy; Wei Huang; Vadivel Ganapathy; Sylvia B Smith
Expression of the extraneuronal monoamine transporter in RPE and neural retina.
Current eye research 2000;20(3):195-204.
2000: Peter Brust; Anne Friedrich; I A Krizbai; Ralf Bergmann; F Roux; Vadivel Ganapathy; Bernd Johannsen
Functional expression of the serotonin transporter in immortalized rat brain microvessel endothelial cells.
Journal of neurochemistry 2000;74(3):1241-8.
2000: R Kekuda; Fred H Leibach; TC Furesz; C H Smith; Vadivel Ganapathy
Polarized distribution of interleukin-1 receptors and their role in regulation of serotonin transporter in placenta.
The Journal of pharmacology and experimental therapeutics 2000;292(3):1032-41.
2000: Malliga E Ganapathy; Wei Huang; DP Rajan; Alva Lee Carter; Mitsuru Sugawara; K Iseki; Fred H Leibach; Vadivel Ganapathy
beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.
The Journal of biological chemistry 2000;275(3):1699-707.
2000: DP Rajan; R Kekuda; Wei Huang; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Cloning and functional characterization of a Na(+)-independent, broad-specific neutral amino acid transporter from mammalian intestine.
Biochimica et biophysica acta 2000;1463(1):6-14.
2000: A A Ogonowski; Wayne H Kaesemeyer; Liming Jin; Vadivel Ganapathy; Fred H Leibach; Robert W Caldwell
Effects of NO donors and synthase agonists on endothelial cell uptake of L-Arg and superoxide production.
American journal of physiology. Cell physiology 2000;278(1):C136-43.
1999: P Seth; X Wu; Wei Huang; Fred H Leibach; Vadivel Ganapathy
Mutations in novel organic cation transporter (OCTN2), an organic cation/carnitine transporter, with differential effects on the organic cation transport function and the carnitine transport function.
The Journal of biological chemistry 1999;274(47):33388-92.
1999: Heng Wang; B Dutta; Wei Huang; Lawrence D Devoe; Fred H Leibach; Vadivel Ganapathy; Puttur D Prasad
Human Na(+)-dependent vitamin C transporter 1 (hSVCT1): primary structure, functional characteristics and evidence for a non-functional splice variant.
Biochimica et biophysica acta 1999;1461(1):1-9.
1999: B Dutta; Wei Huang; Mariela M Molero; R Kekuda; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy; Puttur D Prasad
Cloning of the human thiamine transporter, a member of the folate transporter family.
The Journal of biological chemistry 1999;274(45):31925-9.
1999: Angelika Bröer; Neville Brookes; Vadivel Ganapathy; K S Dimmer; Carsten A Wagner; Florian Lang; Stefan Broer
The astroglial ASCT2 amino acid transporter as a mediator of glutamine efflux.
Journal of neurochemistry 1999;73(5):2184-94.
1999: Ronald L George; X Wu; Wei Huang; You-Jun Fei; Fred H Leibach; Vadivel Ganapathy
Molecular cloning and functional characterization of a polyspecific organic anion transporter from Caenorhabditis elegans.
The Journal of pharmacology and experimental therapeutics 1999;291(2):596-603.
1999: Wei Huang; S N Shaikh; Malliga E Ganapathy; U Hopfer; Fred H Leibach; Alva Lee Carter; Vadivel Ganapathy
Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells.
Biochemical pharmacology 1999;58(8):1361-70.
1999: DP Rajan; R Kekuda; Wei Huang; Heng Wang; Lawrence D Devoe; Fred H Leibach; Puttur D Prasad; Vadivel Ganapathy
Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria.
The Journal of biological chemistry 1999;274(41):29005-10.
1999: DP Rajan; Wei Huang; B Dutta; Lawrence D Devoe; Fred H Leibach; Vadivel Ganapathy; Puttur D Prasad
Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function.
Biochemical and biophysical research communications 1999;262(3):762-8.
1999: X Wu; Wei Huang; Puttur D Prasad; P Seth; DP Rajan; Fred H Leibach; J Chen; Simon J Conway; Vadivel Ganapathy
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1482-92.
1999: T Fujita; T Kishida; N Okada; Vadivel Ganapathy; F H Leibach; A Yamamoto
Interaction of kyotorphin and brain peptide transporter in synaptosomes prepared from rat cerebellum: implication of high affinity type H+/peptide transporter PEPT2 mediated transport system.
Neuroscience letters 1999;271(2):117-20.
1999: T Fujita; Y Majikawa; S Umehisa; N Okada; A Yamamoto; Vadivel Ganapathy; F H Leibach
sigma Receptor ligand-induced up-regulation of the H(+)/peptide transporter PEPT1 in the human intestinal cell line Caco-2.
Biochemical and biophysical research communications 1999;261(2):242-6.
1999: S P Kenney; R Kekuda; Puttur D Prasad; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy
Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta.
American journal of obstetrics and gynecology 1999;181(2):491-7.
1999: Puttur D Prasad; Heng Wang; Wei Huang; You-Jun Fei; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy
Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter.
Archives of biochemistry and biophysics 1999;366(1):95-106.
1999: Heng Wang; Wei Huang; You-Jun Fei; H Xia; TL Yang-Feng; Fred H Leibach; Lawrence D Devoe; Vadivel Ganapathy; Puttur D Prasad
Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization.
The Journal of biological chemistry 1999;274(21):14875-83.
1999: You-Jun Fei; E Nara; J C Liu; C A Boyd; Vadivel Ganapathy; Fred H Leibach
Preferential recognition of zwitterionic dipeptides as transportable substrates by the high-affinity peptide transporter PEPT2.
Biochimica et biophysica acta 1999;1418(2):344-51.
1999: X Wu; You-Jun Fei; Wei Huang; CD Chancy; Fred H Leibach; Vadivel Ganapathy
Identity of the F52F12.1 gene product in Caenorhabditis elegans as an organic cation transporter.
Biochimica et biophysica acta 1999;1418(1):239-44.
1999: Sylvia B Smith; Wei Huang; CD Chancy; Vadivel Ganapathy
Regulation of the reduced-folate transporter by nitric oxide in cultured human retinal pigment epithelial cells.
Biochemical and biophysical research communications 1999;257(2):279-83.
1999: Sylvia B Smith; R Kekuda; Xiaolin Gu; CD Chancy; Simon J Conway; Vadivel Ganapathy
Expression of folate receptor alpha in the mammalian retinol pigmented epithelium and retina.
Investigative ophthalmology & visual science 1999;40(5):840-8.
1999: Malliga E Ganapathy; Puttur D Prasad; Wei Huang; P Seth; Fred H Leibach; Vadivel Ganapathy
Molecular and ligand-binding characterization of the sigma-receptor in the Jurkat human T lymphocyte cell line.
The Journal of pharmacology and experimental therapeutics 1999;289(1):251-60.
1999: Nelson Tang; Vadivel Ganapathy; X Wu; Joannie Hui; P Seth; Patrick Man Pan Yuen; R J Wanders; T F Fok; NM Hjelm
Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency.
Human molecular genetics 1999;8(4):655-60.
1999: Yuhuan Wang; J Ye; Vadivel Ganapathy; Nicola Longo
Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2356-60.
1999: Puttur D Prasad; Heng Wang; Wei Huang; R Kekuda; DP Rajan; Fred H Leibach; Vadivel Ganapathy
Human LAT1, a subunit of system L amino acid transporter: molecular cloning and transport function.
Biochemical and biophysical research communications 1999;255(2):283-8.
1999: R Kekuda; Heng Wang; Wei Huang; Ana M Pajor; Fred H Leibach; Lawrence D Devoe; Puttur D Prasad; Vadivel Ganapathy
Primary structure and functional characteristics of a mammalian sodium-coupled high affinity dicarboxylate transporter.
The Journal of biological chemistry 1999;274(6):3422-9.
1998: X Wu; R Kekuda; Wei Huang; You-Jun Fei; Fred H Leibach; Jeannie Chen; Simon J Conway; Vadivel Ganapathy
Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.
The Journal of biological chemistry 1998;273(49):32776-86.
1998: Ikumi Tamai; Takeo Nakanishi; H Nakahara; Yoshimichi Sai; Vadivel Ganapathy; F H Leibach; Akira Tsuji
Improvement of L-dopa absorption by dipeptidyl derivation, utilizing peptide transporter PepT1.
Journal of pharmaceutical sciences 1998;87(12):1542-6.
1998: H Wang; You-Jun Fei; Vadivel Ganapathy; Fred H Leibach
Electrophysiological characteristics of the proton-coupled peptide transporter PEPT2 cloned from rat brain.
The American journal of physiology 1998;275(4 Pt 1):C967-75.
1998: V Börner; Y J Fei; Bianka Hartrodt; Vadivel Ganapathy; F H Leibach; Klaus Neubert; Matthias Brandsch
Transport of amino acid aryl amides by the intestinal H+/peptide cotransport system, PEPT1.
European journal of biochemistry / FEBS 1998;255(3):698-702.
1998: H He; Vadivel Ganapathy; Carlos M. Isales; Gary M Whitford
pH-dependent fluoride transport in intestinal brush border membrane vesicles.
Biochimica et biophysica acta 1998;1372(2):244-54.
1998: R Kekuda; Puttur D Prasad; X Wu; Heng Wang; You-Jun Fei; Fred H Leibach; Vadivel Ganapathy
Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta.
The Journal of biological chemistry 1998;273(26):15971-9.
1998: You-Jun Fei; T Fujita; David Lapp; Vadivel Ganapathy; Fred H Leibach
Two oligopeptide transporters from Caenorhabditis elegans: molecular cloning and functional expression.
The Biochemical journal 1998;332 ( Pt 2)():565-72.
1998: X Wu; Puttur D Prasad; Fred H Leibach; Vadivel Ganapathy
cDNA sequence, transport function, and genomic organization of human OCTN2, a new member of the organic cation transporter family.
Biochemical and biophysical research communications 1998;246(3):589-95.
1998: Malliga E Ganapathy; Wei Huang; Heng Wang; Vadivel Ganapathy; Fred H Leibach
Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.
Biochemical and biophysical research communications 1998;246(2):470-5.
1998: Y J Fei; J C Liu; T Fujita; R Liang; Vadivel Ganapathy; Fred H Leibach
Identification of a potential substrate binding domain in the mammalian peptide transporters PEPT1 and PEPT2 using PEPT1-PEPT2 and PEPT2-PEPT1 chimeras.
Biochemical and biophysical research communications 1998;246(1):39-44.
1998: V Torres-Zamorano; Fred H Leibach; Vadivel Ganapathy
Sodium-dependent homo- and hetero-exchange of neutral amino acids mediated by the amino acid transporter ATB degree.
Biochemical and biophysical research communications 1998;245(3):824-9.
1998: Puttur D Prasad; Heng Wang; R Kekuda; T Fujita; You-Jun Fei; Lawrence D Devoe; Fred H Leibach; Vadivel Ganapathy
Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate.
The Journal of biological chemistry 1998;273(13):7501-6.
1998: P Seth; You-Jun Fei; HW Li; Wei Huang; Fred H Leibach; Vadivel Ganapathy
Cloning and functional characterization of a sigma receptor from rat brain.
Journal of neurochemistry 1998;70(3):922-31.
1998: Puttur D Prasad; Wei Huang; Heng Wang; Fred H Leibach; Vadivel Ganapathy
Transport mechanisms for vitamin C in the JAR human placental choriocarcinoma cell line.
Biochimica et biophysica acta 1998;1369(1):141-51.
1998: Puttur D Prasad; HW Li; You-Jun Fei; Malliga E Ganapathy; T Fujita; L H Plumley; TL Yang-Feng; Fred H Leibach; Vadivel Ganapathy
Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene.
Journal of neurochemistry 1998;70(2):443-51.
1998: Vadivel Ganapathy; Puttur D Prasad; Fred H Leibach
Use of human placenta in studies of monoamine transporters.
Methods in enzymology 1998;296():278-90.
1998: Y J Fei; Vadivel Ganapathy; F H Leibach
Molecular and structural features of the proton-coupled oligopeptide transporter superfamily.
Progress in nucleic acid research and molecular biology 1998;58():239-61.
1997: P Seth; Fred H Leibach; Vadivel Ganapathy
Cloning and structural analysis of the cDNA and the gene encoding the murine type 1 sigma receptor.
Biochemical and biophysical research communications 1997;241(2):535-40.
1997: DE Bockman; Vadivel Ganapathy; TG Oblak; Fred H Leibach
Localization of peptide transporter in nuclei and lysosomes of the pancreas.
International journal of pancreatology : official journal of the International Association of Pancreatology 1997;22(3):221-5.
1997: Puttur D Prasad; Sammanda Ramamoorthy; Fred H Leibach; Vadivel Ganapathy
Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells.
Placenta 1997;18(7):527-33.
1997: Wei Huang; Puttur D Prasad; R Kekuda; Fred H Leibach; Vadivel Ganapathy
Characterization of N5-methyltetrahydrofolate uptake in cultured human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 1997;38(8):1578-87.
1997: R Kekuda; V Torres-Zamorano; You-Jun Fei; Puttur D Prasad; HW Li; L D Mader; Fred H Leibach; Vadivel Ganapathy
Molecular and functional characterization of intestinal Na(+)-dependent neutral amino acid transporter B0.
The American journal of physiology 1997;272(6 Pt 1):G1463-72.
1997: R Kekuda; Fred H Leibach; Vadivel Ganapathy
Tyrosine phosphorylation-and epidermal growth factor-dependent regulation of the sodium-coupled amino acid transporter B0 in the human placental choriocarcinoma cell line JAR.
Biochimica et biophysica acta 1997;1356(3):258-70.
1997: Puttur D Prasad; V Torres-Zamorano; R Kekuda; Fred H Leibach; Vadivel Ganapathy
Functional link between tyrosine phosphorylation and human serotonin transporter gene expression.
European journal of pharmacology 1997;325(1):85-92.
1997: R Kekuda; V Torres-Zamorano; Fred H Leibach; Vadivel Ganapathy
Human serotonin transporter: regulation by the neuroprotective agent aurintricarboxylic acid and by epidermal growth factor.
Journal of neurochemistry 1997;68(4):1443-50.
1997: Malliga E Ganapathy; Puttur D Prasad; B Mackenzie; Vadivel Ganapathy; Fred H Leibach
Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2.
Biochimica et biophysica acta 1997;1324(2):296-308.
1997: Matthias Brandsch; C Brandsch; Malliga E Ganapathy; Catherine Chew; Vadivel Ganapathy; Fred H Leibach
Influence of proton and essential histidyl residues on the transport kinetics of the H+/peptide cotransport systems in intestine (PEPT 1) and kidney (PEPT 2).
Biochimica et biophysica acta 1997;1324(2):251-62.
1997: Y J Fei; Wen Liu; Puttur D Prasad; R Kekuda; TG Oblak; Vadivel Ganapathy; Fred H Leibach
Identification of the histidyl residue obligatory for the catalytic activity of the human H+/peptide cotransporters PEPT1 and PEPT2.
Biochemistry 1997;36(2):452-60.
1996: R Kekuda; Puttur D Prasad; You-Jun Fei; Fred H Leibach; Vadivel Ganapathy
Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1).
Biochemical and biophysical research communications 1996;229(2):553-8.
1996: B Mackenzie; Y J Fei; Vadivel Ganapathy; F H Leibach
The human intestinal H+/oligopeptide cotransporter hPEPT1 transports differently-charged dipeptides with identical electrogenic properties.
Biochimica et biophysica acta 1996;1284(2):125-8.
1996: Puttur D Prasad; Wei Huang; Sammanda Ramamoorthy; Alva Lee Carter; Fred H Leibach; Vadivel Ganapathy
Sodium-dependent carnitine transport in human placental choriocarcinoma cells.
Biochimica et biophysica acta 1996;1284(1):109-17.
1996: Vadivel Ganapathy; F H Leibach
Peptide transporters.
Current opinion in nephrology and hypertension 1996;5(5):395-400.
1996: R Kekuda; Puttur D Prasad; You-Jun Fei; V Torres-Zamorano; S Sinha; T L Yang-Feng; Fred H Leibach; Vadivel Ganapathy
Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line.
The Journal of biological chemistry 1996;271(31):18657-61.
1996: A S Roque; Puttur D Prasad; Jatinder J Bhatia; Fred H Leibach; Vadivel Ganapathy
Sodium-dependent high-affinity binding of carnitine to human placental brush border membranes.
Biochimica et biophysica acta 1996;1282(2):274-82.
1996: Puttur D Prasad; B J Hoffmans; A J Moe; C H Smith; Fred H Leibach; Vadivel Ganapathy
Functional expression of the plasma membrane serotonin transporter but not the vesicular monoamine transporter in human placental trophoblasts and choriocarcinoma cells.
Placenta 1996;17(4):201-7.
1996: B Mackenzie; Donald D F Loo; Y Fei; W J Liu; Vadivel Ganapathy; F H Leibach; Ernest M Wright
Mechanisms of the human intestinal H+-coupled oligopeptide transporter hPEPT1.
The Journal of biological chemistry 1996;271(10):5430-7.
1996: U Muller; Matthias Brandsch; Puttur D Prasad; You-Jun Fei; Vadivel Ganapathy; Fred H Leibach
Inhibition of the H+/peptide cotransporter in the human intestinal cell line Caco-2 by cyclic AMP.
Biochemical and biophysical research communications 1996;218(2):461-5.
1996: F H Leibach; Vadivel Ganapathy
Peptide transporters in the intestine and the kidney.
Annual review of nutrition 1996;16():99-119.
1995: J D Ramamoorthy; Sammanda Ramamoorthy; Fred H Leibach; Vadivel Ganapathy
Human placental monoamine transporters as targets for amphetamines.
American journal of obstetrics and gynecology 1995;173(6):1782-7.
1995: Sammanda Ramamoorthy; W Liu; Y Y Ma; T L Yang-Feng; Vadivel Ganapathy; Fred H Leibach
Proton/peptide cotransporter (PEPT 2) from human kidney: functional characterization and chromosomal localization.
Biochimica et biophysica acta 1995;1240(1):1-4.
1995: Sammanda Ramamoorthy; J D Ramamoorthy; Puttur D Prasad; GK Bhat; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Regulation of the human serotonin transporter by interleukin-1 beta.
Biochemical and biophysical research communications 1995;216(2):560-7.
1995: Matthias Brandsch; C Brandsch; Puttur D Prasad; Vadivel Ganapathy; U Hopfer; Fred H Leibach
Identification of a renal cell line that constitutively expresses the kidney-specific high-affinity H+/peptide cotransporter.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(14):1489-96.
1995: Malliga E Ganapathy; Matthias Brandsch; Puttur D Prasad; Vadivel Ganapathy; Fred H Leibach
Differential recognition of beta -lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2.
The Journal of biological chemistry 1995;270(43):25672-7.
1995: Vadivel Ganapathy; J D Ramamoorthy; Monte A Delmonte; Fred H Leibach; Sammanda Ramamoorthy
Cyclic AMP-dependent up-regulation of the taurine transporter in a human retinal pigment epithelial cell line.
Current eye research 1995;14(9):843-50.
1995: J D Ramamoorthy; Sammanda Ramamoorthy; Andreas Papapetropoulos; John D Catravas; Fred H Leibach; Vadivel Ganapathy
Cyclic AMP-independent up-regulation of the human serotonin transporter by staurosporine in choriocarcinoma cells.
The Journal of biological chemistry 1995;270(29):17189-95.
1995: You-Jun Fei; Puttur D Prasad; Fred H Leibach; Vadivel Ganapathy
The amino acid transport system y+L induced in Xenopus laevis oocytes by human choriocarcinoma cell (JAR) mRNA is functionally related to the heavy chain of the 4F2 cell surface antigen.
Biochemistry 1995;34(27):8744-51.
1995: Matthias Brandsch; Sammanda Ramamoorthy; N Marczin; John D Catravas; J W Leibach; Vadivel Ganapathy; Fred H Leibach
Regulation of taurine transport by Escherichia coli heat-stable enterotoxin and guanylin in human intestinal cell lines.
The Journal of clinical investigation 1995;96(1):361-9.
1995: TL Yang-Feng; Y Y Ma; R Liang; Puttur D Prasad; F H Leibach; Vadivel Ganapathy
Assignment of the human folate transporter gene to chromosome 21q22.3 by somatic cell hybrid analysis and in situ hybridization.
Biochemical and biophysical research communications 1995;210(3):874-9.
1995: W Liu; R Liang; Sammanda Ramamoorthy; You-Jun Fei; Malliga E Ganapathy; M A Hediger; Vadivel Ganapathy; Fred H Leibach
Molecular cloning of PEPT 2, a new member of the H+/peptide cotransporter family, from human kidney.
Biochimica et biophysica acta 1995;1235(2):461-6.
1995: Lankupalle D Jayanthi; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Substrate-specific regulation of the taurine transporter in human placental choriocarcinoma cells (JAR).
Biochimica et biophysica acta 1995;1235(2):351-60.
1995: R Liang; You-Jun Fei; Puttur D Prasad; Sammanda Ramamoorthy; H Han; T L Yang-Feng; M A Hediger; Vadivel Ganapathy; Fred H Leibach
Human intestinal H+/peptide cotransporter. Cloning, functional expression, and chromosomal localization.
The Journal of biological chemistry 1995;270(12):6456-63.
1995: Matthias Brandsch; Vadivel Ganapathy; Fred H Leibach
H(+)-peptide cotransport in Madin-Darby canine kidney cells: expression and calmodulin-dependent regulation.
The American journal of physiology 1995;268(3 Pt 2):F391-7.
1995: J D Ramamoorthy; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells.
Endocrinology 1995;136(3):924-32.
1995: Puttur D Prasad; Sammanda Ramamoorthy; Fred H Leibach; Vadivel Ganapathy
Molecular cloning of the human placental folate transporter.
Biochemical and biophysical research communications 1995;206(2):681-7.
1994: Vadivel Ganapathy; Fred H Leibach
Human placenta: a direct target for cocaine action.
Placenta 1994;15(8):785-95.
1994: W Liu; Fred H Leibach; Vadivel Ganapathy
Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR).
Biochimica et biophysica acta 1994;1194(1):176-84.
1994: Puttur D Prasad; Sammanda Ramamoorthy; A J Moe; C H Smith; Fred H Leibach; Vadivel Ganapathy
Selective expression of the high-affinity isoform of the folate receptor (FR-alpha) in the human placental syncytiotrophoblast and choriocarcinoma cells.
Biochimica et biophysica acta 1994;1223(1):71-5.
1994: Sammanda Ramamoorthy; Monte A Delmonte; Fred H Leibach; Vadivel Ganapathy
Molecular identity and calmodulin-mediated regulation of the taurine transporter in a human retinal pigment epithelial cell line.
Current eye research 1994;13(7):523-9.
1994: Puttur D Prasad; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells.
Biochimica et biophysica acta 1994;1222(2):309-14.
1994: Matthias Brandsch; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Calmodulin-dependent modulation of pH sensitivity of the amino acid transport system L in human placental choriocarcinoma cells.
Biochimica et biophysica acta 1994;1192(2):177-84.
1994: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; H Han; T Yang-Feng; Randy D Blakely; Vadivel Ganapathy
Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta.
The Biochemical journal 1994;300 ( Pt 3)():893-900.
1994: Lankupalle D Jayanthi; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Calmodulin-dependent regulation of the catalytic function of the human serotonin transporter in placental choriocarcinoma cells.
The Journal of biological chemistry 1994;269(20):14424-9.
1994: Y J Fei; Y Kanai; S Nussberger; Vadivel Ganapathy; F H Leibach; Michael F Romero; S K Singh; Walter F Boron; Matthias A Hediger
Expression cloning of a mammalian proton-coupled oligopeptide transporter.
Nature 1994;368(6471):563-6.
1994: Matthias Brandsch; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Expression and protein kinase C-dependent regulation of peptide/H+ co-transport system in the Caco-2 human colon carcinoma cell line.
The Biochemical journal 1994;299 ( Pt 1)():253-60.
1994: Puttur D Prasad; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Human placenta as a target organ for cocaine action: interaction of cocaine with the placental serotonin transporter.
Placenta 1994;15(3):267-78.
1994: Puttur D Prasad; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Relationship between thyroid hormone transport and neutral amino acid transport in JAR human choriocarcinoma cells.
Endocrinology 1994;134(2):574-81.
1994: P Reinach; Vadivel Ganapathy; V Torres-Zamorano
A Na:H exchanger subtype mediates volume regulation in bovine corneal epithelial cells.
Advances in experimental medicine and biology 1994;350():105-10.
1994: Vadivel Ganapathy; F H Leibach
Expression and regulation of the taurine transporter in cultured cell lines of human origin.
Advances in experimental medicine and biology 1994;359():51-7.
1993: Lankupalle D Jayanthi; Puttur D Prasad; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter.
Biochemistry 1993;32(45):12178-85.
1993: Sammanda Ramamoorthy; D R Cool; Virendra B Mahesh; Fred H Leibach; H E Melikian; Randy D Blakely; Vadivel Ganapathy
Regulation of the human serotonin transporter. Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding.
The Journal of biological chemistry 1993;268(29):21626-31.
1993: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Partial purification and characterization of the human placental serotonin transporter.
Placenta 1993;14(4):449-61.
1993: C Tiruppathi; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Genetic evidence for role of DPP IV in intestinal hydrolysis and assimilation of prolyl peptides.
The American journal of physiology 1993;265(1 Pt 1):G81-9.
1993: D J Pillion; William E Grizzle; M Yang; Elias Meezan; C R Stockard; Vadivel Ganapathy; F H Leibach; R B Myers; J F Haskell
Expression of IGF-II/Man-6-P receptors on rat, rabbit, and human colon epithelial cells.
The American journal of physiology 1993;264(6 Pt 2):R1101-10.
1993: Matthias Brandsch; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Regulation of taurine transport in human colon carcinoma cell lines (HT-29 and Caco-2) by protein kinase C.
The American journal of physiology 1993;264(5 Pt 1):G939-46.
1993: Sammanda Ramamoorthy; Andrea L Bauman; K R Moore; H Han; T Yang-Feng; Albert S Chang; Vadivel Ganapathy; Randy D Blakely
Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2542-6.
1993: Sammanda Ramamoorthy; Puttur D Prasad; P Kulanthaivel; Fred H Leibach; Randy D Blakely; Vadivel Ganapathy
Expression of a cocaine-sensitive norepinephrine transporter in the human placental syncytiotrophoblast.
Biochemistry 1993;32(5):1346-53.
1993: Sammanda Ramamoorthy; P Kulanthaivel; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Solubilization and functional reconstitution of the human placental taurine transporter.
Biochimica et biophysica acta 1993;1145(2):250-6.
1993: J W Leibach; D R Cool; Monte A Delmonte; Vadivel Ganapathy; Fred H Leibach; Y Miyamoto
Properties of taurine transport in a human retinal pigment epithelial cell line.
Current eye research 1993;12(1):29-36.
1993: V Torres-Zamorano; Vadivel Ganapathy; P Reinach
Characterization and subtype identification of the Na(+)-H+ exchanger in bovine corneal epithelium.
Current eye research 1993;12(1):69-76.
1992: Puttur D Prasad; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles. Transport and binding.
The Journal of biological chemistry 1992;267(33):23632-9.
1992: C Tiruppathi; Matthias Brandsch; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Constitutive expression of the taurine transporter in a human colon carcinoma cell line.
The American journal of physiology 1992;263(5 Pt 1):G625-31.
1992: B J Simon; P Kulanthaivel; G Burckhardt; Sammanda Ramamoorthy; Fred H Leibach; Vadivel Ganapathy
Characterization of an ATP-driven H+ pump in human placental brush-border membrane vesicles.
The Biochemical journal 1992;287 ( Pt 2)():423-30.
1992: Sammanda Ramamoorthy; D R Cool; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Reconstitution of the human placental 5-hydroxytryptamine transporter in a catalytically active form after detergent solubilization.
The Biochemical journal 1992;286 ( Pt 1)():89-95.
1992: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Modulation of the activity of amino acid transport system L by phorbol esters and calmodulin antagonists in a human placental choriocarcinoma cell line.
Biochimica et biophysica acta 1992;1136(2):181-8.
1992: V Torres-Zamorano; Vadivel Ganapathy; Mohamed M Sharawy; P Reinach
Evidence for an ATP-driven H(+)-pump in the plasma membrane of the bovine corneal epithelium.
Experimental eye research 1992;55(2):269-77.
1992: Sammanda Ramamoorthy; Fred H Leibach; V B Mahesh; Vadivel Ganapathy
Selective impairment of taurine transport by cyclosporin A in a human placental cell line.
Pediatric research 1992;32(1):125-7.
1992: P Kulanthaivel; TC Furesz; A J Moe; Carl H Smith; V B Mahesh; Fred H Leibach; Vadivel Ganapathy
Human placental syncytiotrophoblast expresses two pharmacologically distinguishable types of Na(+)-H+ exchangers, NHE-1 in the maternal-facing (brush border) membrane and NHE-2 in the fetal-facing (basal) membrane.
The Biochemical journal 1992;284 ( Pt 1)():33-8.
1992: Sammanda Ramamoorthy; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Active transport of dopamine in human placental brush-border membrane vesicles.
The American journal of physiology 1992;262(5 Pt 1):C1189-96.
1992: S Sivakami; Vadivel Ganapathy; Fred H Leibach; Y Miyamoto
The gamma-aminobutyric acid transporter and its interaction with taurine in the apical membrane of the bovine retinal pigment epithelium.
The Biochemical journal 1992;283 ( Pt 2)():391-7.
1992: Carl H Smith; A J Moe; Vadivel Ganapathy
Nutrient transport pathways across the epithelium of the placenta.
Annual review of nutrition 1992;12():183-206.
1991: Sammanda Ramamoorthy; C Tiruppathi; C N Nair; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Relative sensitivity to inhibition by cimetidine and clonidine differentiates between the two types of Na(+)-H+ exchangers in cultured cells.
The Biochemical journal 1991;280 ( Pt 2)():317-22.
1991: C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Transport of peptides in renal brush border membrane vesicles. Suitability of 125I-labelled tyrosyl peptides as substrates.
Biochimica et biophysica acta 1991;1069(1):14-20.
1991: Vadivel Ganapathy; Y Miyamoto; C Tiruppathi; Fred H Leibach
Peptide transport across the animal cell plasma membrane: recent developments.
Indian journal of biochemistry & biophysics 1991;28(5-6):317-23.
1991: D R Cool; Fred H Leibach; V K Bhalla; Virendra B Mahesh; Vadivel Ganapathy
Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR).
The Journal of biological chemistry 1991;266(24):15750-7.
1991: Y Miyamoto; P Kulanthaivel; Fred H Leibach; Vadivel Ganapathy
Taurine uptake in apical membrane vesicles from the bovine retinal pigment epithelium.
Investigative ophthalmology & visual science 1991;32(9):2542-51.
1991: Vadivel Ganapathy; Fred H Leibach
Proton-coupled solute transport in the animal cell plasma membrane.
Current opinion in cell biology 1991;3(4):695-701.
1991: P Kulanthaivel; Y Miyamoto; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Inactivation of taurine transporter by calcium in purified human placental brush border membrane vesicles.
Placenta 1991;12(4):327-40.
1991: P Kulanthaivel; D R Cool; Sammanda Ramamoorthy; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line.
The Biochemical journal 1991;277 ( Pt 1)():53-8.
1991: Vadivel Ganapathy; F H Leibach
Protons and regulation of biological functions.
Kidney international. Supplement 1991;33():S4-10.
1991: Y Miyamoto; Y G Thompson; E F Howard; Vadivel Ganapathy; Fred H Leibach
Functional expression of the intestinal peptide-proton co-transporter in Xenopus laevis oocytes.
The Journal of biological chemistry 1991;266(8):4742-5.
1990: Y Miyamoto; P Kulanthaivel; Vadivel Ganapathy; Gary M Whitford; Fred H Leibach
Calcium-induced inhibition of taurine transport in brush-border membrane vesicles from rabbit small intestine.
Biochimica et biophysica acta 1990;1030(2):189-94.
1990: P Kulanthaivel; B J Simon; G Burckhardt; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
The ATP-binding site of the human placental H+ pump contains essential tyrosyl residues.
Biochemistry 1990;29(48):10807-13.
1990: D R Cool; F H Liebach; Vadivel Ganapathy
Interaction of fluoxetine with the human placental serotonin transporter.
Biochemical pharmacology 1990;40(9):2161-7.
1990: C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Kinetic evidence for a common transporter for glycylsarcosine and phenylalanylprolylalanine in renal brush-border membrane vesicles.
The Journal of biological chemistry 1990;265(25):14870-4.
1990: Y Miyamoto; H Nakamura; T Hoshi; Vadivel Ganapathy; F H Leibach
Uphill transport of beta-alanine in intestinal brush-border membrane vesicles.
The American journal of physiology 1990;259(3 Pt 1):G372-9.
1990: D R Cool; Fred H Leibach; Vadivel Ganapathy
High-affinity paroxetine binding to the human placental serotonin transporter.
The American journal of physiology 1990;259(2 Pt 1):C196-204.
1990: P Kulanthaivel; B J Simon; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
An essential role for vicinal dithiol groups in the catalytic activity of the human placental Na(+)-H+ exchanger.
Biochimica et biophysica acta 1990;1024(2):385-9.
1990: C Tiruppathi; P Kulanthaivel; Vadivel Ganapathy; Fred H Leibach
Evidence for tripeptide/H+ co-transport in rabbit renal brush-border membrane vesicles.
The Biochemical journal 1990;268(1):27-33.
1990: D R Cool; Fred H Leibach; Vadivel Ganapathy
Modulation of serotonin uptake kinetics by ions and ion gradients in human placental brush-border membrane vesicles.
Biochemistry 1990;29(7):1818-22.
1990: C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Evidence for tripeptide-proton symport in renal brush border membrane vesicles. Studies in a novel rat strain with a genetic absence of dipeptidyl peptidase IV.
The Journal of biological chemistry 1990;265(4):2048-53.
1990: P Kulanthaivel; Fred H Leibach; Virendra B Mahesh; E J Cragoe; Vadivel Ganapathy
The Na(+)-H+ exchanger of the placental brush-border membrane is pharmacologically distinct from that of the renal brush-border membrane.
The Journal of biological chemistry 1990;265(3):1249-52.
1990: C Tiruppathi; Y Miyamoto; Vadivel Ganapathy; R A Roesel; Gary M Whitford; Fred H Leibach
Hydrolysis and transport of proline-containing peptides in renal brush-border membrane vesicles from dipeptidyl peptidase IV-positive and dipeptidyl peptidase IV-negative rat strains.
The Journal of biological chemistry 1990;265(3):1476-83.
1990: Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Peptidases and peptide transport in renal brush-border membrane vesicles from rats with acute renal failure.
The Journal of pharmacology and experimental therapeutics 1990;252(1):98-103.
1989: P Kulanthaivel; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Tyrosine residues are essential for the activity of the human placental taurine transporter.
Biochimica et biophysica acta 1989;985(2):139-46.
1989: Vadivel Ganapathy; P Kulanthaivel; C Tiruppathi; Virendra B Mahesh; Fred H Leibach
Inactivation of the human placental serotonin transporter by tyrosyl group-specific reagents.
The Journal of pharmacology and experimental therapeutics 1989;251(1):9-15.
1989: Y Miyamoto; C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Active transport of taurine in rabbit jejunal brush-border membrane vesicles.
The American journal of physiology 1989;257(1 Pt 1):G65-72.
1989: D J Pillion; J F Haskell; J A Atchison; Vadivel Ganapathy; F H Leibach
Receptors for IGF-I, but not for IGF-II, on proximal colon epithelial cell apical membranes.
The American journal of physiology 1989;257(1 Pt 1):E27-34.
1989: Y Miyamoto; C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Multiple transport systems for organic cations in renal brush-border membrane vesicles.
The American journal of physiology 1989;256(4 Pt 2):F540-8.
1989: D F Balkovetz; C Tiruppathi; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membranes.
The Journal of biological chemistry 1989;264(4):2195-8.
1989: Y Miyamoto; C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Involvement of thiol groups in the function of the dipeptide/proton cotransport system in rabbit renal brush-border membrane vesicles.
Biochimica et biophysica acta 1989;978(1):25-31.
1988: C Tiruppathi; D F Balkovetz; Vadivel Ganapathy; Y Miyamoto; Fred H Leibach
A proton gradient, not a sodium gradient, is the driving force for active transport of lactate in rabbit intestinal brush-border membrane vesicles.
The Biochemical journal 1988;256(1):219-23.
1988: D F Balkovetz; F H Leibach; V B Mahesh; Vadivel Ganapathy
A proton gradient is the driving force for uphill transport of lactate in human placental brush-border membrane vesicles.
The Journal of biological chemistry 1988;263(27):13823-30.
1988: Delon W Barfuss; Vadivel Ganapathy; F H Leibach
Evidence for active dipeptide transport in isolated proximal straight tubules.
The American journal of physiology 1988;255(1 Pt 2):F177-81.
1988: Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Transport of guanidine in rabbit intestinal brush-border membrane vesicles.
The American journal of physiology 1988;255(1 Pt 1):G85-92.
1988: Y Miyamoto; D F Balkovetz; Vadivel Ganapathy; T Iwatsubo; M Hanano; Fred H Leibach
Effects of phenothiazines on the Na+-H+ exchanger of the brush-border membrane from the proximal small intestine of the rabbit.
The Journal of pharmacology and experimental therapeutics 1988;245(3):823-8.
1988: Y Miyamoto; D F Balkovetz; Fred H Leibach; Virendra B Mahesh; Vadivel Ganapathy
Na+ + Cl- -gradient-driven, high-affinity, uphill transport of taurine in human placental brush-border membrane vesicles.
FEBS letters 1988;231(1):263-7.
1988: Vadivel Ganapathy; Malliga E Ganapathy; C N Nair; Virendra B Mahesh; Fred H Leibach
Evidence for an organic cation-proton antiport system in brush-border membranes isolated from the human term placenta.
The Journal of biological chemistry 1988;263(10):4561-8.
1988: C Tiruppathi; Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Fatty acid-induced alterations in transport systems of the small intestinal brush-border membrane.
Biochemical pharmacology 1988;37(7):1399-405.
1988: Y Miyamoto; J L Coone; Vadivel Ganapathy; Fred H Leibach
Distribution and properties of the glycylsarcosine-transport system in rabbit renal proximal tubule. Studies with isolated brush-border-membrane vesicles.
The Biochemical journal 1988;249(1):247-53.
1988: Vadivel Ganapathy; Malliga E Ganapathy; C Tiruppathi; Y Miyamoto; Virendra B Mahesh; Fred H Leibach
Sodium-gradient-driven, high-affinity, uphill transport of succinate in human placental brush-border membrane vesicles.
The Biochemical journal 1988;249(1):179-84.
1988: Y Miyamoto; Vadivel Ganapathy; Fred H Leibach
Role of dipeptidylpeptidase IV in renal handling of peptides.
Contributions to nephrology 1988;68():1-5.
1987: C Tiruppathi; Vadivel Ganapathy; Fred H Leibach
Development of dipeptide transport in rat renal brush border membranes: studies with glycylsarcosine.
Pediatric research 1987;22(6):641-6.
1987: D F Balkovetz; Y Miyamoto; C Tiruppathi; Virendra B Mahesh; Fred H Leibach; Vadivel Ganapathy
Inhibition of brush-border membrane Na+-H+ exchanger by loperamide.
The Journal of pharmacology and experimental therapeutics 1987;243(1):150-4.
1987: S Silbernagl; Vadivel Ganapathy; F H Leibach
H+ gradient-driven dipeptide reabsorption in proximal tubule of rat kidney. Studies in vivo and in vitro.
The American journal of physiology 1987;253(3 Pt 2):F448-57.
1987: Vadivel Ganapathy; D F Balkovetz; Malliga E Ganapathy; Virendra B Mahesh; Lawrence D Devoe; Fred H Leibach
Evidence for histidyl and carboxy groups at the active site of the human placental Na+-H+ exchanger.
The Biochemical journal 1987;245(2):473-7.
1987: Y Miyamoto; Vadivel Ganapathy; A Barlas; K Neubert; A Barth; F H Leibach
Role of dipeptidyl peptidase IV in uptake of peptide nitrogen from beta-casomorphin in rabbit renal BBMV.
The American journal of physiology 1987;252(4 Pt 2):F670-7.
1987: S K Garg; Vadivel Ganapathy; P K Bandhopadhya; S K Gupta; R J Dash
Pyrexia of unknown origin as rare presentation of tuberculous thyroiditis.
The Indian journal of chest diseases & allied sciences 1987;29(1):52-5.
1987: Vadivel Ganapathy; Y Miyamoto; F H Leibach
Driving force for peptide transport in mammalian intestine and kidney.
Beiträge zu Infusionstherapie und klinische Ernährung 1987;17():54-68.
1986: Y Miyamoto; Vadivel Ganapathy; F H Leibach
Identification of histidyl and thiol groups at the active site of rabbit renal dipeptide transporter.
The Journal of biological chemistry 1986;261(34):16133-40.
1986: Vadivel Ganapathy; F H Leibach
Carrier-mediated reabsorption of small peptides in renal proximal tubule.
The American journal of physiology 1986;251(6 Pt 2):F945-53.
1986: D F Balkovetz; F H Leibach; V B Mahesh; Lawrence D Devoe; E J Cragoe; Vadivel Ganapathy
Na+-H+ exchanger of human placental brush-border membrane: identification and characterization.
The American journal of physiology 1986;251(6 Pt 1):C852-60.
1986: Malliga E Ganapathy; F H Leibach; V B Mahesh; Lawrence D Devoe; Vadivel Ganapathy
Interaction of clonidine with human placental Na+ -H+ exchanger.
Biochemical pharmacology 1986;35(22):3989-94.
1986: Vadivel Ganapathy; D F Balkovetz; Y Miyamoto; Malliga E Ganapathy; Virendra B Mahesh; Lawrence D Devoe; Fred H Leibach
Inhibition of human placental Na+-H+ exchanger by cimetidine.
The Journal of pharmacology and experimental therapeutics 1986;239(1):192-7.
1986: Malliga E Ganapathy; F H Leibach; V B Mahesh; J C Howard; Lawrence D Devoe; Vadivel Ganapathy
Characterization of tryptophan transport in human placental brush-border membrane vesicles.
The Biochemical journal 1986;238(1):201-8.
1985: Y Miyamoto; Vadivel Ganapathy; F H Leibach
Proton gradient-coupled uphill transport of glycylsarcosine in rabbit renal brush-border membrane vesicles.
Biochemical and biophysical research communications 1985;132(3):946-53.
1985: Malliga E Ganapathy; V B Mahesh; Lawrence D Devoe; F H Leibach; Vadivel Ganapathy
Dipeptide transport in brush-border membrane vesicles isolated from normal term human placenta.
American journal of obstetrics and gynecology 1985;153(1):83-6.
1985: Vadivel Ganapathy; G Burckhardt; F H Leibach
Peptide transport in rabbit intestinal brush-border membrane vesicles studied with a potential-sensitive dye.
Biochimica et biophysica acta 1985;816(2):234-40.
1985: D J Pillion; Vadivel Ganapathy; F H Leibach
Identification of insulin receptors on the mucosal surface of colon epithelial cells.
The Journal of biological chemistry 1985;260(9):5244-7.
1985: Vadivel Ganapathy; S J Pashley; R A Roesel; David H Pashley; F H Leibach
Inhibition of rat and human prolidases by captopril.
Biochemical pharmacology 1985;34(8):1287-91.
1985: R A Roesel; P R Blankenship; Vadivel Ganapathy; Fred H Leibach
5-Hydroxy-L-lysine excretion in cystinuria.
Journal of inherited metabolic disease 1985;8(3):123-6.
1984: Vadivel Ganapathy; G Burckhardt; F H Leibach
Characteristics of glycylsarcosine transport in rabbit intestinal brush-border membrane vesicles.
The Journal of biological chemistry 1984;259(14):8954-9.
1984: Vadivel Ganapathy; David H Pashley; M C Fonteles; F H Leibach
Peptidases and peptide transport in mammalian kidney.
Contributions to nephrology 1984;42():10-8.
1983: Vadivel Ganapathy; F H Leibach
Role of pH gradient and membrane potential in dipeptide transport in intestinal and renal brush-border membrane vesicles from the rabbit. Studies with L-carnosine and glycyl-L-proline.
The Journal of biological chemistry 1983;258(23):14189-92.
1983: M C Fonteles; Vadivel Ganapathy; David H Pashley; F H Leibach
Dipeptide metabolism in the isolated perfused rat kidney.
Life sciences 1983;33(5):431-6.
1983: Vadivel Ganapathy; F H Leibach
Electrogenic transport of 5-oxoproline in rabbit renal brush-border membrane vesicles. Effect of intravesicular potassium.
Biochimica et biophysica acta 1983;732(1):32-40.
1983: Vadivel Ganapathy; R A Roesel; J C Howard; F H Leibach
Interaction of proline, 5-oxoproline, and pipecolic acid for renal transport in the rabbit.
The Journal of biological chemistry 1983;258(4):2266-72.
1982: Vadivel Ganapathy; F H Leibach
Transport and utilization of methionine sulfoxide in the rabbit.
Biochimica et biophysica acta 1982;693(2):305-14.
1982: V Kannan; Vadivel Ganapathy
XXX infertility syndrome.
The Journal of the Association of Physicians of India 1982;30(12):910-1.
1982: Vadivel Ganapathy; M Fonteles; David H Pashley; F H Leibach
Prolidase contamination in commercial bovine serum albumin.
Biochimica et biophysica acta 1982;719(1):154-7.
1982: Vadivel Ganapathy; F H Leibach
Peptide transport in rabbit kidney. Studies with L-carnosine.
Biochimica et biophysica acta 1982;691(2):362-6.
1982: Vadivel Ganapathy; F H Leibach
Peptide transport in intestinal and renal brush border membrane vesicles.
Life sciences 1982;30(25):2137-46.
1982: Vadivel Ganapathy; R A Roesel; F H Leibach
Transport of 5-oxoproline into rabbit renal brush border membrane vesicles.
Biochemical and biophysical research communications 1982;105(1):28-35.
1981: Vadivel Ganapathy; J F Mendicino; F H Leibach
Effect of papain treatment on dipeptide transport into rabbit intestinal brush border vesicles.
Life sciences 1981;29(24):2451-7.
1981: Vadivel Ganapathy; J Mendicino; F H Leibach
Evidence for a dipeptide transport system in renal brush border membranes from rabbit.
Biochimica et biophysica acta 1981;642(2):381-91.
1981: Vadivel Ganapathy; J F Mendicino; F H Leibach
Transport of glycyl-L-proline into intestinal and renal brush border vesicles from rabbit.
The Journal of biological chemistry 1981;256(1):118-24.
1980: Vadivel Ganapathy; J Mendicino; David H Pashley; F H Leibach
Carrier-mediated transport of glycyl-L-proline in renal brush border vesicles.
Biochemical and biophysical research communications 1980;97(3):1133-9.
1980: M D Hellier; Vadivel Ganapathy; A Gammon; V I Mathan; A N Radhakrishnan
Impaired intestinal absorption of dipeptide in tropical sprue patients in India.
Clinical science (London, England : 1979) 1980;58(5):431-3.
1980: Vadivel Ganapathy; A N Radhakrishnan
Sodium-dependent inhibition of amino acid and dipeptide transport by harmaline in monkey small intestine.
Biochemical pharmacology 1980;29(5):713-6.
1979: Vadivel Ganapathy; A N Radhakrishnan
Interaction of amino acids with glycl-L-leucine hydrolysis and transport in monkey small intestine.
Clinical science (London, England : 1979) 1979;57(6):521-7.
1977: Vadivel Ganapathy; A N Radhakrishnan
A convenient paper chromatographic method for determination of dipeptides.
Indian journal of biochemistry & biophysics 1977;14(1):83-4.
1976: M D Hellier; A N Radhakrishnan; Vadivel Ganapathy; V I Mathan; S J Baker
Intestinal perfusion studies in tropical sprue. 1. Amino acid and dipeptide absorption.
Gut 1976;17(7):511-6.
1976: M D Hellier; A N Radhakrishnan; Vadivel Ganapathy; A Gammon; S J Baker
Intestinal absorption in normal Indian and English people.
British medical journal 1976;1(6003):186-8.
1975: M D Hellier; Vadivel Ganapathy; A N Radhakrishnan; S J Baker
A comparative study of intestinal absorption in normal Indian and English subjects using a perfusion technique.
Gut 1975;16(10):844.