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José Castro

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Silvia L Fanelli; María E Maciel; MI Díaz Gómez; Aurora M A Delgado de Layño; Florencia M Bietto; José A Castro; Gerardo D Castro
Further studies on the potential contribution of acetaldehyde accumulation and oxidative stress in rat mammary tissue in the alcohol drinking promotion of breast cancer.
Laura C Bartel; María Montalto de Mecca; Carmen Rodríguez de Castro; Florencia Matilde Bietto; José A Castro
Metabolization of nifurtimox and benznidazole in cellular fractions of rat mammary tissue.
Mónica Faut; Carmen Rodríguez de Castro; Florencia M Bietto; José A Castro; Gerardo D Castro
Metabolism of ethanol to acetaldehyde and increased susceptibility to oxidative stress could play a role in the ovarian tissue cell injury promoted by alcohol drinking.

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2011: Silvia L Fanelli; María E Maciel; MI Díaz Gómez; Aurora M A Delgado de Layño; Florencia M Bietto; José A Castro; Gerardo D Castro
Further studies on the potential contribution of acetaldehyde accumulation and oxidative stress in rat mammary tissue in the alcohol drinking promotion of breast cancer.
Journal of applied toxicology : JAT 2011;31(1):11-9.
2010: Laura C Bartel; María Montalto de Mecca; Carmen Rodríguez de Castro; Florencia Matilde Bietto; José A Castro
Metabolization of nifurtimox and benznidazole in cellular fractions of rat mammary tissue.
Human & experimental toxicology 2010;29(10):813-22.
2009: Mónica Faut; Carmen Rodríguez de Castro; Florencia M Bietto; José A Castro; Gerardo D Castro
Metabolism of ethanol to acetaldehyde and increased susceptibility to oxidative stress could play a role in the ovarian tissue cell injury promoted by alcohol drinking.
Toxicology and industrial health 2009;25(8):525-38.
2009: Laura C Bartel; María Montalto de Mecca; José A Castro
Nitroreductive metabolic activation of some carcinogenic nitro heterocyclic food contaminants in rat mammary tissue cellular fractions.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(1):140-4.
2008: María Montalto de Mecca; Laura C Bartel; Carmen Rodríguez de Castro; José A Castro
Benznidazole biotransformation in rat heart microsomal fraction without observable ultrastructural alterations: comparison to Nifurtimox-induced cardiac effects.
Memórias do Instituto Oswaldo Cruz 2008;103(6):549-53.
2008: Gerardo D Castro; A M A Delgado de Layño; Silvia L Fanelli; M E Maciel; M I Díaz Gómez; José A Castro
Acetaldehyde accumulation in rat mammary tissue after an acute treatment with alcohol.
Journal of applied toxicology : JAT 2008;28(3):315-21.
2007: Laura C Bartel; María Montalto de Mecca; Silvia L Fanelli; C Rodriguez de Castro; EG Diaz; José A Castro
Early nifurtimox-induced biochemical and ultrastructural alterations in rat heart.
Human & experimental toxicology 2007;26(10):781-8.
2007: M I Díaz Gómez; Carmen R de Castro; Silvia L Fanelli; L N Quintans; Martín H Costantini; José A Castro; Gerardo D Castro
Biochemical and ultrastructural alterations in the rat ventral prostate due to repetitive alcohol drinking.
Journal of applied toxicology : JAT 2007;27(4):391-8.
2007: María Montalto de Mecca; Silvia L Fanelli; Laura C Bartel; Carmen R de Castro; Edith G Díaz; José A Castro
Nifurtimox nitroreductase activity in different cellular fractions from male rat pancreas. Biochemical and ultrastructural alterations.
Life sciences 2007;81(2):144-52.
2006: Maria I Diaz Gómez; Silvia L Fanelli; Aurora M A Delgado de Layño; José A Castro; Gerardo D Castro
Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet.
Toxicology and industrial health 2006;22(9):367-74.
2006: José A Castro; Maria Montalto de Mecca; Laura C Bartel
Toxic side effects of drugs used to treat Chagas' disease (American trypanosomiasis).
Human & experimental toxicology 2006;25(8):471-9.
2006: Gerardo D Castro; Carmen R de Castro; María E Maciel; Silvia L Fanelli; Elida Cignoli de Ferreyra; M I Díaz Gómez; José A Castro
Ethanol-induced oxidative stress and acetaldehyde formation in rat mammary tissue: potential factors involved in alcohol drinking promotion of breast cancer.
Toxicology 2006;219(1-3):208-19.
2005: Leandro N Quintans; Gerardo D Castro; José A Castro
Oxidation of ethanol to acetaldehyde and free radicals by rat testicular microsomes.
Archives of toxicology 2005;79(1):25-30.
2004: Edith G Díaz; María Montalto de Mecca; José A Castro
Reactions of nifurtimox with critical sulfhydryl-containing biomolecules: their potential toxicological relevance.
Journal of applied toxicology : JAT 2004;24(3):189-95.
2004: Maria Eugenia Maciel; Gerardo D Castro; José A Castro
Inhibition of the rat breast cytosolic bioactivation of ethanol to acetaldehyde by some plant polyphenols and folic acid.
Nutrition and cancer 2004;49(1):94-9.
2003: Carmen R de Castro; María Montalto de Mecca; Silvia L Fanelli; Elida C de Ferreyra; Edith G Díaz; José A Castro
Benznidazole-induced ultrastructural and biochemical alterations in rat esophagus.
Toxicology 2003;191(2-3):189-98.
2003: Gerardo D Castro; Aurora M A Delgado de Layño; Martín H Costantini; José A Castro
Rat breast microsomal biotransformation of ethanol to acetaldehyde but not to free radicals: its potential role in the association between alcohol drinking and breast tumor promotion.
Teratogenesis, carcinogenesis, and mutagenesis 2003;Suppl 1():61-70.
2002: María Montalto de Mecca; EG Diaz; José A Castro
Nifurtimox biotransformation to reactive metabolites or nitrite in liver subcellular fractions and model systems.
Toxicology letters 2002;136(1):1-8.
2002: Adriana Silvina Bernacchi; Berta Franke De Cazzulo; José A Castro
Trypanocidal action of 2,4-dichloro-6-phenylphenoxyethyl diethylamine hydrobromide (Lilly 18947) on Trypanosoma cruzi.
Acta pharmacologica Sinica 2002;23(5):399-404.
2002: Gerardo D Castro; Martín H Costantini; Aurora M A Delgado de Layño; José A Castro
Rat liver microsomal and nuclear activation of methanol to hydroxymethyl free radicals.
Toxicology letters 2002;129(3):227-36.
2002: Gerardo D Castro; Aurora M A Delgado de Layño; Martín H Costantini; José A Castro
Rat ventral prostate microsomal biotransformation of ethanol to acetaldehyde and 1-hydroxyethyl radicals: its potential contribution to prostate tumor promotion.
Teratogenesis, carcinogenesis, and mutagenesis 2002;22(5):335-41.
2002: José A Castro; Gerardo D Castro
Hydroxyl and 1-hydroxyethyl radical detection by spin trapping and GC-MS.
Methods in molecular biology (Clifton, N.J.) 2002;186():89-99.
2002: M I Díaz Gómez; E Valles; Silvia L Fanelli; A M A Delgado de Layño; Gerardo D Castro; José A Castro
Alcohol induction of liver nuclear ethanol and N-nitrosodimethylamine metabolism to reactive metabolites.
Teratogenesis, carcinogenesis, and mutagenesis 2002;22(2):139-45.
2001: Gerardo D Castro; Aurora M A Delgado de Layño; Martín H Costantini; José A Castro
Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer.
Toxicology 2001;160(1-3):11-8.
2001: María Montalto de Mecca; C Rodríguez de Castro; Edith G Díaz; José A Castro
[Ultrastructural alterations in colonic mucosa of nifurtimox treated rats].
Medicina 2001;61(1):67-72.
2001: Gerardo D Castro; Aurora M A Delgado de Layño; Martín H Costantini; José A Castro
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
Teratogenesis, carcinogenesis, and mutagenesis 2001;21(2):109-19.
2000: José A Castro
Contributions of toxicology to the problem of Chagas' disease (American Trypanosomiasis)--a year 2000 update.
Biomedical and environmental sciences : BES 2000;13(4):271-9.
2000: MI Díaz Gómez; Gerardo D Castro; A M de Layño; Martín H Costantini; José A Castro
Cytochrome P450 reductase-mediated anaerobic biotransformation of ethanol to 1-hydroxyethyl-free radicals and acetaldehyde.
Toxicology 2000;154(1-3):113-22.
2000: EG Diaz; C Rodriguez de Castro; María Montalto de Mecca; José A Castro
Benznidazole-induced ultrastructural and biochemical alterations in rat colon.
Acta pharmacologica Sinica 2000;21(11):961-6.
2000: María Montalto de Mecca; Adriana Silvina Bernacchi; José A Castro
Prevention of benznidazole-induced prolonging effect on the pentobarbital sleeping time of rats using different thiol-containing compounds.
Research communications in molecular pathology and pharmacology 2000;108(1-2):39-48.
1999: MI Díaz Gómez; Silvia L Fanelli; Gerardo D Castro; Martín H Costantini; José A Castro
A liver nuclear ethanol metabolizing system. Formation of metabolites that bind covalently to macromolecules and lipids.
Toxicology 1999;138(1):19-28.
1998: Silvia L Fanelli; Gerardo D Castro; E G de Toranzo; José A Castro
Mechanisms of the preventive properties of some garlic components in the carbon tetrachloride-promoted oxidative stress. Diallyl sulfide; diallyl disulfide; allyl mercaptan and allyl methyl sulfide.
Research communications in molecular pathology and pharmacology 1998;102(2):163-74.
1998: Gerardo D Castro; Aurora M A Delgado de Layño; José A Castro
Liver nuclear ethanol metabolizing systems (NEMS) producing acetaldehyde and 1-hydroxyethyl free radicals.
Toxicology 1998;129(2-3):137-44.
1998: M E Galelli; José A Castro
Effect of trichloromethyl and trichloromethyl peroxyl free radicals on protein sulfhydryl content studies in model and in enzymatic carbon tetrachloride activation systems.
Research communications in molecular pathology and pharmacology 1998;100(2):227-38.
1997: E G de Toranzo; D M Herrera; José A Castro
Rat liver nuclear nifurtimox nitroreductase activity.
Research communications in molecular pathology and pharmacology 1997;98(3):249-54.
1997: Gerardo D Castro; Aurora M A Delgado de Layño; José A Castro
Hydroxyl and 1-hydroxyethyl free radical detection using spin traps followed by derivatization and gas chromatography-mass spectrometry.
Redox report : communications in free radical research 1997;3(5-6):343-7.
1997: Gerardo D Castro; José A Castro
Promotion of the formation of phenylalanine-thymine cross-linked products by free radicals formed during carbon tetrachloride activation with benzoyl peroxide in model systems. A mass spectrometric structural study.
Research communications in molecular pathology and pharmacology 1997;98(1):85-90.
1997: Gerardo D Castro; MI Díaz Gómez; José A Castro
DNA bases attack by reactive metabolites produced during carbon tetrachloride biotransformation and promotion of liver microsomal lipid peroxidation.
Research communications in molecular pathology and pharmacology 1997;95(3):253-8.
1996: M M de Mecca; Gerardo D Castro; José A Castro
Dithiothreitol tetraacetate S-acetyl esterase activity in different liver subcellular fractions and its potential role in the ester-mediated prevention of oxidative stress induced cell damage.
Research communications in molecular pathology and pharmacology 1996;94(2):211-6.
1996: Gerardo D Castro; M I Díaz Gómez; José A Castro
5-Methylcytosine attack by hydroxyl free radicals and during carbon tetrachloride promoted liver microsomal lipid peroxidation: structure of reaction products.
Chemico-biological interactions 1996;99(1-3):289-99.
1996: A González Padrón; E G de Toranzo; José A Castro
Depression of liver microsomal glucose 6-phosphatase activity in carbon tetrachloride-poisoned rats. Potential synergistic effects of lipid peroxidation and of covalent binding of haloalkane-derived free radicals to cellular components in the process.
Free radical biology & medicine 1996;21(1):81-7.
1995: Silvia L Fanelli; Gerardo D Castro; José A Castro
Cholesterol interaction with free radicals produced from carbon tetrachloride or bromotrichloromethane by either catalytic decomposition or via liver microsomal activation.
Chemico-biological interactions 1995;98(3):223-36.
1995: Gerardo D Castro; C J Stamato; José A Castro
Reaction of bromotrichloromethane derived free radicals with uracil in a model system. Structures of products formed.
Free radical research 1995;23(5):431-42.
1995: E G Valles; C R de Castro; José A Castro
Radioprotectors as late preventive agents against carbon tetrachloride induced liver necrosis: protection by 2-(3-aminopropylamino) ethylphosphorothioic acid (WR2721).
Experimental and molecular pathology 1995;63(2):101-9.
1995: E C de Ferreyra; A S Bernacchi; M F San Martin; Gerardo D Castro; José A Castro
Late protective effects of the anticalmodulin drug fluphenazine on carbon tetrachloride-induced liver necrosis.
Biomedical and environmental sciences : BES 1995;8(3):218-25.
1995: M M de Mecca; Gerardo D Castro; M I Díaz Gómez; José A Castro
Dithiothreitol inhibitory effects on carbon tetrachloride-promoted NADPH-dependent lipid peroxidation in liver microsomal suspensions.
Research communications in molecular pathology and pharmacology 1995;88(2):205-13.
1995: E C de Ferreyra; A S Bernacchi; M F San Martin; Gerardo D Castro; José A Castro
Trifluopromazine late preventive effects on carbon tetrachloride-induced liver necrosis.
Experimental and molecular pathology 1995;62(2):75-82.
1995: Silvia L Fanelli; José A Castro
Covalent binding of carbon tetrachloride reactive metabolites to liver microsomal and nuclear lipid and phospholipid classes from Sprague Dawley and osborne Mendel male rats.
Teratogenesis, carcinogenesis, and mutagenesis 1995;15(4):155-66.
1995: Gerardo D Castro; C J Stamato; José A Castro
Proline interaction with trichloromethyl and trichloromethyl peroxyl free radicals in a model system: studies about the nature of the reaction products formed.
Drug metabolism reviews 1995;27(1-2):257-75.
1994: E G de Toranzo; José A Castro
Reaction of 4-hydroxynonenal with some thiol-containing radioprotective agents or their active metabolites.
Free radical biology & medicine 1994;17(6):605-7.
1994: Gerardo D Castro; C J Stamato; José A Castro
5-methylcytosine attack by free radicals arising from bromotrichloromethane in a model system: structures of reaction products.
Free radical biology & medicine 1994;17(5):419-28.
1994: Gerardo D Castro; C J Stamato; José A Castro
Tyrosine attack by free radicals derived from catalytic decomposition of carbon tetrachloride.
Free radical biology & medicine 1994;16(6):693-701.
1994: E C de Ferreyra; A S Bernacchi; M F San Martín; Gerardo D Castro; José A Castro
Nicotinamide late protective effects against carbon tetrachloride-induced liver necrosis.
Experimental and molecular pathology 1994;60(3):214-23.
1994: E G Valles; C R de Castro; José A Castro
Late protective effects against CCl4-induced liver necrosis by the radioprotective agent 2-aminoethyl-isothiouronium bromide hydrobromide (AET).
Toxicology 1994;90(1-2):71-80.
1994: E G Valles; C R de Castro; José A Castro
N-acetyl cysteine is an early but also a late preventive agent against carbon tetrachloride-induced liver necrosis.
Toxicology letters 1994;71(1):87-95.
1994: Gerardo D Castro; J T Simpson; José A Castro
Interaction of trichloromethyl free radicals with thymine in a model system: a mass spectrometric study.
Chemico-biological interactions 1994;90(1):13-22.
1994: M Galelli; M I Díaz Gómez; José A Castro
Decreased incorporation of 14C-leucine in different liver nuclear protein fractions at early stages of carbon tetrachloride poisoning in the rat.
Archives of toxicology 1994;68(3):206-9.
1993: Silvia L Fanelli; José A Castro
Carbon tetrachloride promoted malondialdehyde formation in liver microsomal and nuclear preparations from Sprague Dawley or Osborne Mendel male rats.
Research communications in chemical pathology and pharmacology 1993;82(2):233-6.
1993: M M de Mecca; Gerardo D Castro; José A Castro
Dithiothreitol tetraacetate S-acetyl esterase activity in blood and in different tissues of male rats.
Archives internationales de pharmacodynamie et de thérapie 1993;326():101-8.
1993: E C de Ferreyra; A S Bernacchi; M C Villarruel; O M de Fenos; José A Castro
Prevention of CCl4-induced liver necrosis by the calcium chelator arsenazo III.
Experimental and molecular pathology 1993;58(3):194-204.
1993: A S Bernacchi; E C de Ferreyra; C R de Castro; José A Castro
Ultrastructural alterations in testes from rats treated with cysteine.
Biomedical and environmental sciences : BES 1993;6(2):172-8.
1993: José A Castro; M I Díaz Gómez; Gerardo D Castro
Non-genotoxic carcinogens. Approaches to their risk assessment.
Biomedical and environmental sciences : BES 1993;6(1):71-80.
1993: M M de Mecca; Gerardo D Castro; José A Castro
Antioxidative stress therapy with dithiothreitol tetraacetate. I. Protection against carbon tetrachloride induced liver necrosis.
Archives of toxicology 1993;67(8):547-51.
1993: A González Padrón; E G de Toranzo; José A Castro
Late preventive effects of quinacrine on carbon tetrachloride induced liver necrosis.
Archives of toxicology 1993;67(6):386-91.
1992: C R de Castro; E G Diaz de Toranzo; José A Castro
Benznidazole-induced ultrastructural alterations in rat adrenal cortex. Mechanistic studies.
Toxicology 1992;74(2-3):223-32.
1992: E C de Ferreyra; M C Villarruel; A S Bernacchi; O M de Fenos; José A Castro
Prevention of carbon tetrachloride-induced liver necrosis by the chelator alizarin sodium sulfonate.
Experimental and molecular pathology 1992;56(3):197-207.
1992: O Acosta de Pérez; A S Bernacchi; E G Díaz de Toranzo; José A Castro
Reductive biotransformation of xenobiotics by the sheep ruminal content.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1992;101(3):625-6.
1991: JL Lacuara; Susana R de Barioglio; P P de Oliva; A S Bernacchi; A F de Culasso; José A Castro; B M Franke de Cazzulo; Juan J Cazzulo
Disruption of mitochondrial function as the basis of the trypanocidal effect of trifluoperazine on Trypanosoma cruzi.
Experientia 1991;47(6):612-6.
1991: Gerardo D Castro; M I Díaz Gómez; José A Castro
Interaction of trichloromethyl radicals with phenylalanine.
Archives of toxicology 1991;65(4):340-3.
1990: Gerardo D Castro; M I Díaz Gómez; José A Castro
Biotransformation of carbon tetrachloride and lipid peroxidation promotion by liver nuclear preparations from different animal species.
Cancer letters 1990;53(1):9-15.
1990: M C Villarruel; G Fernández; E C de Ferreyra; O M de Fenos; José A Castro
Modulation of the course of CCl4-induced liver injury by the anti-calmodulin drug thioridazine.
Toxicology letters 1990;51(1):13-21.
1990: C R de Castro; E G De Toranzo; M Carbone; José A Castro
Ultrastructural effects of Nifurtimox on rat adrenal cortex related to reductive biotransformation.
Experimental and molecular pathology 1990;52(1):98-108.
1989: Gerardo D Castro; M I Díaz Gómez; José A Castro
Dimethyldisulfide formation during trichloromethyl radical attack on methionine.
Biochemical pharmacology 1989;38(22):4145-7.
1989: C R de Castro; E G de Toranzo; A S Bernacchi; M Carbone; José A Castro
Ultrastructural alterations in ovaries from nifurtimox or benznidazole-treated rats: their relation to ovarian nitroreductive biotransformation of both drugs.
Experimental and molecular pathology 1989;50(3):385-97.
1989: E C de Ferreyra; M C Villarruel; G Fernández; O M de Fenos; A S Bernacchi; C R de Castro; José A Castro
Further studies on the mechanism of the late protective effects of phenylmethylsulfonyl fluoride on carbon tetrachloride-induced liver necrosis.
Experimental and molecular pathology 1989;50(2):253-69.
1989: Gerardo D Castro; M I Díaz Gómez; José A Castro
Species differences in the interaction between CCl4 reactive metabolites and liver DNA or nuclear protein fractions.
Carcinogenesis 1989;10(2):289-94.
1989: E C de Ferreyra; M C Villarruel; A S Bernacchi; G Fernández; O M de Fenos; José A Castro
Late preventive effects against carbon tetrachloride-induced liver necrosis of the calcium chelating agent Calcion.
Archives of toxicology 1989;63(6):450-5.
1989: O A de Perez; E C de Ferreyra; A S Bernacchi; M C Villarruel; O M de Fenos; José A Castro
Carbon tetrachloride-induced liver cell injury in the Mongolian gerbil (Meriones unguiculatus).
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1989;94(2):357-64.
1988: E G Díaz de Toranzo; José A Castro; B M Franke de Cazzulo; Juan J Cazzulo
Interaction of benznidazole reactive metabolites with nuclear and kinetoplastic DNA, proteins and lipids from Trypanosoma cruzi.
Experientia 1988;44(10):880-1.
1988: M I Díaz Gómez; D Tamayo; José A Castro
Nitrosodimethylamine metabolism in rat ovaries. Interactions of its metabolites with nucleic acids and proteins.
Cancer letters 1988;41(3):257-63.
1988: A S Bernacchi; G Fernández; M C Villarruel; E C de Ferreyra; C R de Castro; O M de Fenos; José A Castro
Further studies on the late preventive effects of the anticalmodulin trifluoperazine on carbon tetrachloride-induced liver necrosis.
Experimental and molecular pathology 1988;48(3):286-300.
1988: M C Villarruel; E C de Ferreyra; A S Bernacchi; José A Castro
Glutathione (GSH) content in livers from control and carbon tetrachloride poisoned rats treated with the calmodulin inhibitors thioridazine, imipramine or chlorpromazine.
Research communications in chemical pathology and pharmacology 1988;60(3):397-400.
1988: Gerardo D Castro; A Lopez; José A Castro
Evidence for hydroxyl free radical formation during paraquat but not for nifurtimox liver microsomal biotransformation. A dimethyl-sulfoxide scavenging study.
Archives of toxicology 1988;62(5):355-8.
1987: E Aguilar; C K de Arranz; E G de Toranzo; José A Castro
Liver microsomal benznidazole and nifurtimox nitroreductase activity in male rats of different age.
Archives internationales de pharmacodynamie et de thérapie 1987;289(1):11-7.
1987: E G Aguilar; C Koldobsky; E G de Toranzo; José A Castro
Species and sex differences in the liver microsomal nitroreductive biotransformation of nifurtimox and benznidazole.
Archives internationales de pharmacodynamie et de thérapie 1987;287(2):181-7.
1987: M C Villarruel; G Fernández; E G Aguilar; José A Castro
Early biochemical alterations in liver mitochondria from carbon tetrachloride poisoned rats.
Journal of applied toxicology : JAT 1987;7(3):173-7.
1987: A S Bernacchi; C R de Castro; E G de Toranzo; E C de Ferreyra; O M de Fenos; José A Castro
Effects of carbon tetrachloride on the liver of chickens. Early biochemical and ultrastructural alterations in the absence of detectable lipid peroxidation.
Xenobiotica; the fate of foreign compounds in biological systems 1987;17(2):223-8.
1986: A S Bernacchi; C R de Castro; E G de Toranzo; José A Castro
Effects of nifurtimox or benznidazole administration on rat testes: ultrastructural observations and biochemical studies.
Experimental and molecular pathology 1986;45(3):245-56.
1986: G Fernández; M C Villarruel; E C de Ferreyra; O M de Fenos; José A Castro
Imipramine prevention of carbon tetrachloride-induced liver necrosis at late states of the intoxication process.
Journal of applied toxicology : JAT 1986;6(6):413-8.
1986: E C de Ferreyra; A S Bernacchi; José A Castro
Increased glutathione (GSH) content in livers of control and carbon tetrachloride poisoned rats treated with the anticalmodulin drug trifluoperazine (TFP).
Research communications in chemical pathology and pharmacology 1986;53(3):399-402.
1986: M C Villarruel; G Fernández; E C de Ferreyra; O M de Fenos; José A Castro
Late preventive effects of trifluoperazine on carbon tetrachloride-induced hepatic necrosis.
Toxicology and applied pharmacology 1986;83(2):287-93.
1986: G Fernández; M C Villarruel; José A Castro
Effect of chlorpromazine on protein, phospholipid and RNA synthesis or degradation in rat liver.
Drug and chemical toxicology 1986;9(1):41-9.
1985: E G Aguilar; C K de Arranz; E G de Toranzo; José A Castro
Benznidazole and nifurtimox nitroreductase activity in liver microsomes from male rats preinduced with phenobarbital or 3-methylcholanthrene.
Research communications in chemical pathology and pharmacology 1985;50(3):443-6.
1984: C R de Castro; A S Bernacchi; M C Villarruel; G Fernández; José A Castro
Carbon tetrachloride activation by highly purified liver mitochondrial preparations.
Agents and actions 1984;15(5-6):664-7.
1984: G Fernández; M C Villarruel; E C de Ferreyra; O M de Fenos; A S Bernacchi; C R de Castro; José A Castro
Carbon tetrachloride-induced early biochemical alterations but not necrosis in pigeon's liver.
Agents and actions 1984;15(3-4):463-6.
1984: G Fernández; M C Villarruel; José A Castro
Effect of cystamine on protein, phospholipid and RNA synthesis or degradation.
Research communications in chemical pathology and pharmacology 1984;43(3):511-4.
1984: H M Godoy; M I Díaz Gómez; José A Castro
Metabolism and activation of 1,1-dimethylhydrazine and methylhydrazine, two products of N-nitrosodimethylamine reductive biotransformation.
IARC scientific publications 1984;(57):479-84.
1983: H M Godoy; M I Díaz Gómez; José A Castro
Metabolism and activation of 1,1-dimethylhydrazine and methylhydrazine, two products of nitrosodimethylamine reductive biotransformation, in rats.
Journal of the National Cancer Institute 1983;71(5):1047-51.
1983: N Gorla; E C de Ferreyra; M C Villarruel; O M de Fenos; José A Castro
Studies on the mechanism of glutathione prevention of carbon tetrachloride-induced liver injury.
British journal of experimental pathology 1983;64(4):388-95.
1983: A S Bernacchi; C R de Castro; E C de Ferreyra; M C Villarruel; G Fernández; O M de Fenos; José A Castro
Carbon tetrachloride-induced liver injury in the rabbit.
British journal of experimental pathology 1983;64(3):261-7.
1983: E G De Toranzo; E C De Ferreyra; O M De Fenos; José A Castro
Prevention of carbon tetrachloride-induced liver necrosis by several amino acids.
British journal of experimental pathology 1983;64(2):166-71.
1983: M I Díaz Gómez; H M Godoy; M C Villarruel; José A Castro
No response of pigeon liver to dimethylnitrosamine acute effects.
Cancer letters 1983;18(2):157-62.
1982: H M Godoy; M I Díaz Gómez; A Marzi; E C de Ferreyra; O M de Fenos; José A Castro
Chicken resistance to dimethylnitrosamine acute effects on the liver: a comparative study with other species.
Journal of the National Cancer Institute 1982;69(3):687-91.
1982: M C Villarruel; G Fernández; E C de Ferreyra; O M de Fenos; José A Castro
Studies on the mechanism of alloxan-diabetes potentiation of carbon tetrachloride-induced liver necrosis.
British journal of experimental pathology 1982;63(4):388-93.
1982: G Fernández; M C Villarruel; E G de Toranzo; José A Castro
Covalent binding of carbon tetrachloride metabolites to the heme moiety of cytochrome P-450 and its degradation products.
Research communications in chemical pathology and pharmacology 1982;35(2):283-90.
1982: A S Bernacchi; C R de Castro; E C de Ferreyra; O M de Fenos; José A Castro
Effect of 3 amino 1,2,4 triazole administration on the early CCl4-induced ultrastructural alterations in rat liver.
British journal of experimental pathology 1982;63(1):35-42.
1981: M I Díaz Gómez; H M Godoy; A Marzi; E C de Ferreyra; O M de Fenos; José A Castro
Enhancement of the dimethylnitrosamine acute effects in rat liver by prior treatment with triton WR-1339.
Journal of the National Cancer Institute 1981;67(5):1089-92.
1981: E C de Ferreyra; E G de Toranzo; O M de Fenos; José A Castro
Studies on the mechanism of enhancement of carbon tetrachloride hepatotoxicity by Triton WR 1339.
British journal of experimental pathology 1981;62(5):512-8.
1981: G Fernández; M C Villarruel; A Bernacchi; C R de Castro; José A Castro
Liver microsomal drug-metabolizing enzyme activity: enhancement by blockade of degradative processes in promethazine-treated rats.
British journal of experimental pathology 1981;62(5):440-5.
1981: E G de Toranzo; A Marzi; José A Castro
Effects of cysteine and cystamine on the carbon tetrachloride induced decrease in arachidonic acid content of rat liver microsomal phospholipids.
Toxicology 1981;19(1):77-82.
1981: G Fernández; M C Villarruel; A Bernacchi; C R de Castro; José A Castro
Effects of repeated administration of rat 2-diethylaminoethyl-2-2-diphenylvalerate-HCI (SKF 525 A) on liver.
Toxicology 1981;20(2-3):185-93.
1980: A Marzi; E G de Toranzo; José A Castro
Studies on the prevention of CCl4 induced liver necrosis by agents having effects on cell membrane.
Research communications in chemical pathology and pharmacology 1980;30(3):581-4.
1980: A S Bernacchi; C R de Castro; E G de Toranzo; A Marzi; E C de Ferreyra; O M de Fenos; José A Castro
Pyrazole prevention of CC14-induced ultrastructural changes in rat liver.
British journal of experimental pathology 1980;61(5):505-11.
1980: E G de Toranzo; A Marzi; José A Castro
Promethazine administration to rats and CCl4 induced lipid peroxidation of liver microsomal lipids.
Research communications in chemical pathology and pharmacology 1980;30(1):91-8.
1980: A Marzi; E G de Toranzo; José A Castro
Mechanism of chlorpromazine prevention of carbon tetrachloride-induced liver necrosis.
Toxicology and applied pharmacology 1980;52(1):82-8.