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Kathleen O'Connor

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Chemicals & Drugs

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TOP 3
Kathleen O'Connor; Min Chen; L Nicole Towers
Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation.
Carlos A Murillo; Kenneth Jeffrey Woodside; Qian Guo; Shu Zhang; Kathleen O'Connor; Glenn C Hunter
Integrin and matrix metalloproteinase expression in human carotid plaque.
Adriana A Paulucci-Holthauzen; Leoncio A Vergara; Larry J Bellot; David Canton; John D Scott; Kathleen O'Connor
Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc.

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All Publications

2012: Kathleen O'Connor; Min Chen; L Nicole Towers
Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation.
American journal of physiology. Cell physiology 2012;302(3):C605-14.
2009: Carlos A Murillo; Kenneth Jeffrey Woodside; Qian Guo; Shu Zhang; Kathleen O'Connor; Glenn C Hunter
Integrin and matrix metalloproteinase expression in human carotid plaque.
The Journal of surgical research 2009;155(1):157-64.
2009: Adriana A Paulucci-Holthauzen; Leoncio A Vergara; Larry J Bellot; David Canton; John D Scott; Kathleen O'Connor
Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc.
The Journal of biological chemistry 2009;284(9):5956-67.
2009: Min Chen; Mala Sinha; Bruce A Luxon; Anne R Bresnick; Kathleen O'Connor
Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin.
The Journal of biological chemistry 2009;284(3):1484-94.
2008: Zobeida Cruz-Monserrate; Kathleen O'Connor
Integrin alpha 6 beta 4 promotes migration, invasion through Tiam1 upregulation, and subsequent Rac activation.
Neoplasia (New York, N.Y.) 2008;10(5):408-17.
2007: Zobeida Cruz-Monserrate; Suimin Qiu; B Mark Evers; Kathleen O'Connor
Upregulation and redistribution of integrin alpha6beta4 expression occurs at an early stage in pancreatic adenocarcinoma progression.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(6):656-67.
2007: Min Chen; L Nicole Towers; Kathleen O'Connor
LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells.
American journal of physiology. Cell physiology 2007;292(5):C1927-33.
2007: Jing Li; Kathleen O'Connor; Xiaodong Cheng; Fang C Mei; Tatsuo Uchida; Courtney M Townsend; B Mark Evers
Cyclic adenosine 5'-monophosphate-stimulated neurotensin secretion is mediated through Rap1 downstream of both Epac and protein kinase A signaling pathways.
Molecular endocrinology (Baltimore, Md.) 2007;21(1):159-71.
2006: Adriana A Paulucci-Holthauzen; Kathleen O'Connor
Use of pseudosubstrate affinity to measure active protein kinase A.
Analytical biochemistry 2006;355(2):175-82.
2005: Min Chen; Kathleen O'Connor
Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells.
Oncogene 2005;24(32):5125-30.
2005: Jing Li; Kathleen O'Connor; George H Greeley; Perry Blackshear; Courtney M Townsend; B Mark Evers
Myristoylated alanine-rich C kinase substrate-mediated neurotensin release via protein kinase C-delta downstream of the Rho/ROK pathway.
The Journal of biological chemistry 2005;280(9):8351-7.
2004: Jing Li; Kathleen O'Connor; Mark R Hellmich; George H Greeley; Courtney M Townsend; B Mark Evers
The role of protein kinase D in neurotensin secretion mediated by protein kinase C-alpha/-delta and Rho/Rho kinase.
The Journal of biological chemistry 2004;279(27):28466-74.
2003: Buckminster Farrow; Piotr G Rychahou; Kathleen O'Connor; B Mark Evers
Butyrate inhibits pancreatic cancer invasion.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003;7(7):864-70.
2003: Buckminster Farrow; Kathleen O'Connor; Koji Hashimoto; Takeshi Iwamura; B Mark Evers
Selective activation of PPARgamma inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator.
Surgery 2003;134(2):206-12.
2003: Buckminster Farrow; Piotr G Rychahou; Carlos A Murillo; Kathleen O'Connor; Takeshi Iwamura; B Mark Evers
Inhibition of pancreatic cancer cell growth and induction of apoptosis with novel therapies directed against protein kinase A.
Surgery 2003;134(2):197-205.
2001: Kathleen O'Connor; Arthur M Mercurio
Protein kinase A regulates Rac and is required for the growth factor-stimulated migration of carcinoma cells.
The Journal of biological chemistry 2001;276(51):47895-900.
2001: Arthur M Mercurio; Robin E Bachelder; Jun Chung; Kathleen O'Connor; Isaac Rabinovitz; Leslie M Shaw; T Tani
Integrin laminin receptors and breast carcinoma progression.
Journal of mammary gland biology and neoplasia 2001;6(3):299-309.
2001: Arthur M Mercurio; Robin E Bachelder; Isaac Rabinovitz; Kathleen O'Connor; T Tani; Leslie M Shaw
The metastatic odyssey: the integrin connection.
Surgical oncology clinics of North America 2001;10(2):313-28, viii-ix.
2000: Kathleen O'Connor; B K Nguyen; Arthur M Mercurio
RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism.
The Journal of cell biology 2000;148(2):253-8.
1998: Kathleen O'Connor; Leslie M Shaw; Arthur M Mercurio
Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells.
The Journal of cell biology 1998;143(6):1749-60.
1998: Lloyd A Culp; W Lin; Nanette Kleinman; Kathleen O'Connor; R Lechner
Earliest steps in primary tumor formation and micrometastasis resolved with histochemical markers of gene-tagged tumor cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(5):557-68.
1994: Kathleen O'Connor; Lloyd A Culp
Quantitation of two histochemical markers in the same extract using chemiluminescent substrates.
BioTechniques 1994;17(3):502-6, 508-9.
1993: W C Lin; Kathleen O'Connor; Lloyd A Culp
Complementation of two related tumour cell classes during experimental metastasis tagged with different histochemical marker genes.
British journal of cancer 1993;67(5):910-21.