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John Hanover

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Peng Wang; Michele E Forsythe; Michael W Krause; Brooke D Lazarus; Dona C Love; John Hanover
O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.
Dong Wook Kim; Mark Willingham; Li Zhao; John Hanover; Sheue-Yann Cheng
Thyroid hormone receptor β suppresses SV40-mediated tumorigenesis via novel nongenomic actions.
Sang-Hoon Shin; Dona C Love; John Hanover
Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis.

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All Publications

2012: Peng Wang; Michele E Forsythe; Michael W Krause; Brooke D Lazarus; Dona C Love; John Hanover
O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(43):17669-74.
2012: Dong Wook Kim; Mark Willingham; Li Zhao; John Hanover; Sheue-Yann Cheng
Thyroid hormone receptor β suppresses SV40-mediated tumorigenesis via novel nongenomic actions.
American journal of cancer research 2012;2(5):606-19.
2011: Sang-Hoon Shin; Dona C Love; John Hanover
Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis.
Amino acids 2011;40(3):885-93.
2011: John Hanover
A versatile sugar transferase makes the cut.
Cell 2011;144(3):321-3.
2010: John Hanover
Epigenetics gets sweeter: O-GlcNAc joins the "histone code".
Chemistry & biology 2010;17(12):1272-4.
2010: Osamu Sekine; Dona C Love; David S Rubenstein; John Hanover
Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis.
The Journal of biological chemistry 2010;285(49):38684-91.
2010: Eun Ju Kim; Dona C Love; Etzer Darout; Mohannad Abdo; Brian Rempel; Stephen G Withers; Paul R Rablen; John Hanover; Spencer Knapp
OGA inhibition by GlcNAc-selenazoline.
Bioorganic & medicinal chemistry 2010;18(19):7058-64.
2010: Dona C Love; Michael W Krause; John Hanover
O-GlcNAc cycling: emerging roles in development and epigenetics.
Seminars in cell & developmental biology 2010;21(6):646-54.
2010: Dona C Love; Salil Ghosh; Michelle A Mondoux; Tetsunari Fukushige; Peng Wang; Mark A Wilson; Wendy B Iser; Catherine A Wolkow; Michael W Krause; John Hanover
Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(16):7413-8.
2010: John Hanover; Michael W Krause; Dona C Love
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine.
Biochimica et biophysica acta 2010;1800(2):80-95.
2009: Brooke D Lazarus; Dona C Love; John Hanover
O-GlcNAc cycling: implications for neurodegenerative disorders.
The international journal of biochemistry & cell biology 2009;41(11):2134-46.
2009: John Hanover; Dona C Love; William A Prinz
Calmodulin-driven nuclear entry: trigger for sex determination and terminal differentiation.
The Journal of biological chemistry 2009;284(19):12593-7.
2009: Shuzhen Chen; Johnathan R Whetstine; Salil Ghosh; John Hanover; Reddy R Gali; Paul Grosu; Yang Shi
The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1496-501.
2008: Ewa Krawczyk; Frank A Suprynowicz; Xuefeng Liu; Yuhai Dai; Dan P Hartmann; John Hanover; Richard Schlegel
Koilocytosis: a cooperative interaction between the human papillomavirus E5 and E6 oncoproteins.
The American journal of pathology 2008;173(3):682-8.
2008: Ewa Krawczyk; John Hanover; Richard Schlegel; Frank A Suprynowicz
Karyopherin beta3: a new cellular target for the HPV-16 E5 oncoprotein.
Biochemical and biophysical research communications 2008;371(4):684-8.
2008: Jan Hajduch; Ghilsoo Nam; Eun Ju Kim; Roland Fröhlich; John Hanover; Kenneth L Kirk
A convenient synthesis of the C-1-phosphonate analogue of UDP-GlcNAc and its evaluation as an inhibitor of O-linked GlcNAc transferase (OGT).
Carbohydrate research 2008;343(2):189-95.
2007: Eun J Kim; Benjamin Amorelli; Mohannad Abdo; Craig J Thomas; Dona C Love; Spencer Knapp; John Hanover
Distinctive inhibition of O-GlcNAcase isoforms by an alpha-GlcNAc thiolsulfonate.
Journal of the American Chemical Society 2007;129(48):14854-5.
2007: John Hanover; Dona C Love; Nikki DeAngelis; Meghan E O'Kane; Raquel Lima-Miranda; Timothy Schulz; Yi-Meng Yen; Reid C Johnson; William A Prinz
The High Mobility Group Box Transcription Factor Nhp6Ap enters the nucleus by a calmodulin-dependent, Ran-independent pathway.
The Journal of biological chemistry 2007;282(46):33743-51.
2007: Fumihiko Furuya; Céline J Guigon; Li Zhao; Changxue Lu; John Hanover; Sheue-Yann Cheng
Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling.
Molecular and cellular biology 2007;27(17):6116-26.
2007: Spencer Knapp; Mohannad Abdo; Kehinde Ajayi; Richard A Huhn; Thomas J Emge; Eun Ju Kim; John Hanover
Tautomeric modification of GlcNAc-thiazoline.
Organic letters 2007;9(12):2321-4.
2007: Yongge Zhao; Dietrich B Conze; John Hanover; Jonathan D Ashwell
Tumor necrosis factor receptor 2 signaling induces selective c-IAP1-dependent ASK1 ubiquitination and terminates mitogen-activated protein kinase signaling.
The Journal of biological chemistry 2007;282(11):7777-82.
2007: Caroline S Kim; Fumihiko Furuya; Hao Ying; Yasuhito Kato; John Hanover; Sheue-Yann Cheng
Gelsolin: a novel thyroid hormone receptor-beta interacting protein that modulates tumor progression in a mouse model of follicular thyroid cancer.
Endocrinology 2007;148(3):1306-12.
2006: Hao Ying; Fumihiko Furuya; Li Zhao; Osamu Araki; Brian L West; John Hanover; Mark C Willingham; Sheue-Yann Cheng
Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.
The Journal of clinical investigation 2006;116(11):2972-84.
2006: Michele E Forsythe; Dona C Love; Brooke D Lazarus; Eun Ju Kim; William A Prinz; Gilbert Ashwell; Michael W Krause; John Hanover
Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):11952-7.
2006: Eun Ju Kim; Dae Ook Kang; Dona C Love; John Hanover
Enzymatic characterization of O-GlcNAcase isoforms using a fluorogenic GlcNAc substrate.
Carbohydrate research 2006;341(8):971-82.
2006: Brooke D Lazarus; Dona C Love; John Hanover
Recombinant O-GlcNAc transferase isoforms: identification of O-GlcNAcase, yes tyrosine kinase, and tau as isoform-specific substrates.
Glycobiology 2006;16(5):415-21.
2006: Eun Ju Kim; Melissa Perreira; Craig J Thomas; John Hanover
An O-GlcNAcase-specific inhibitor and substrate engineered by the extension of the N-acetyl moiety.
Journal of the American Chemical Society 2006;128(13):4234-5.
2006: Fumihiko Furuya; John Hanover; Sheue-Yann Cheng
Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1780-5.
2006: Melissa Perreira; Eun Ju Kim; Craig J Thomas; John Hanover
Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry.
Bioorganic & medicinal chemistry 2006;14(3):837-46.
2005: Dona C Love; John Hanover
The hexosamine signaling pathway: deciphering the "O-GlcNAc code".
Science's STKE : signal transduction knowledge environment 2005;2005(312):re13.
2005: Delia C Tang; Jianqiong Zhu; Wenli Liu; Kyung Chin; Jun Sun; Ling Chen; John Hanover; Griffin P Rodgers
The hydroxyurea-induced small GTP-binding protein SAR modulates gamma-globin gene expression in human erythroid cells.
Blood 2005;106(9):3256-63.
2005: Brooke D Lazarus; Mark D Roos; John Hanover
Mutational analysis of the catalytic domain of O-linked N-acetylglucosaminyl transferase.
The Journal of biological chemistry 2005;280(42):35537-44.
2005: Allan Bar-Sinai; Nir Bassa; Maria Fischette; Michael M Gottesman; Dona C Love; John Hanover; Jacob Hochman
Mouse mammary tumor virus Env-derived peptide associates with nucleolar targets in lymphoma, mammary carcinoma, and human breast cancer.
Cancer research 2005;65(16):7223-30.
2005: John Hanover; Michele E Forsythe; Patrick T Hennessey; Thomas M Brodigan; Dona C Love; Gilbert Ashwell; Michael Krause
A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11266-71.
2005: Chuan-Jin Wu; Dietrich B Conze; Xiaoming Li; Sai-Xia Ying; John Hanover; Jonathan D Ashwell
TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination.
The EMBO journal 2005;24(10):1886-98.
2005: Gary L Disbrow; John Hanover; Richard Schlegel
Endoplasmic reticulum-localized human papillomavirus type 16 E5 protein alters endosomal pH but not trans-Golgi pH.
Journal of virology 2005;79(9):5839-46.
2004: Martin Jínek; Jan Rehwinkel; Brooke D Lazarus; Elisa Izaurralde; John Hanover; Elena Conti
The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha.
Nature structural & molecular biology 2004;11(10):1001-7.
2003: Mei Zhang; M Sun; Nancy K Dwyer; Marcy Comly; Shutish C Patel; R Sundaram; John Hanover; E Joan Blanchette-Mackie
Differential trafficking of the Niemann-Pick C1 and 2 proteins highlights distinct roles in late endocytic lipid trafficking.
Acta paediatrica (Oslo, Norway : 1992). Supplement 2003;92(443):63-73; discussion 45.
2003: Wen-Chi Tsai; Nisan Bhattacharyya; Li-Ying Han; John Hanover; Matthew M Rechler
Insulin inhibition of transcription stimulated by the forkhead protein Foxo1 is not solely due to nuclear exclusion.
Endocrinology 2003;144(12):5615-22.
2003: David J Vocadlo; Howard C Hang; Eun-Ju Kim; John Hanover; Carolyn R Bertozzi
A chemical approach for identifying O-GlcNAc-modified proteins in cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9116-21.
2003: Gary L Disbrow; Iruvanti Sunitha; Carl Baker; John Hanover; Richard Schlegel
Codon optimization of the HPV-16 E5 gene enhances protein expression.
Virology 2003;311(1):105-14.
2003: S S Chauhan; Xing-Jie Liang; A W Su; Atmaram Pai Panandiker; Ding-Wu Shen; John Hanover; Michael M Gottesman
Reduced endocytosis and altered lysosome function in cisplatin-resistant cell lines.
British journal of cancer 2003;88(8):1327-34.
2003: Dona C Love; Jarema Kochan; R Lamont Cathey; Sang-Hoon Shin; John Hanover; Jarema Kochran
Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase.
Journal of cell science 2003;116(Pt 4):647-54.
2003: John Hanover; Song Yu; William B Lubas; Sang Hoon Shin; Maria Ragano-Caracciola; Jarema Kochran; Dona C Love
Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene.
Archives of biochemistry and biophysics 2003;409(2):287-97.
2002: Mei Zhang; Pei Liu; Nancy K Dwyer; Lane K Christenson; Toshio Fujimoto; Federico Martinez; Marcy Comly; John Hanover; E Joan Blanchette-Mackie; Jerome F Strauss
MLN64 mediates mobilization of lysosomal cholesterol to steroidogenic mitochondria.
The Journal of biological chemistry 2002;277(36):33300-10.
2002: Donald A McClain; William A Lubas; Robert C Cooksey; Mark Hazel; Glendon J Parker; Dona C Love; John Hanover
Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10695-9.
2002: Anjan G Thakurta; William A Whalen; Jin Ho Yoon; Anekella Bharathi; Libor Kozak; Craig Whiteford; Dona C Love; John Hanover; Ravi Dhar
Crp79p, like Mex67p, is an auxiliary mRNA export factor in Schizosaccharomyces pombe.
Molecular biology of the cell 2002;13(8):2571-84.
2001: Huei-Min Lin; Masahiro Kaneshige; Ling Zhao; X Zhang; John Hanover; Sheue-Yann Cheng
An isoform of branched-chain aminotransferase is a novel co-repressor for thyroid hormone nuclear receptors.
The Journal of biological chemistry 2001;276(51):48196-205.
2001: Yongzhi Cui; M Li; KD Walton; K Sun; John Hanover; Priscilla A Furth; Lothar Hennighausen
The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue.
Genomics 2001;78(3):129-34.
2001: John Hanover
Glycan-dependent signaling: O-linked N-acetylglucosamine.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):1865-76.
2001: Mei Zhang; Nancy K Dwyer; Dona C Love; Adele Cooney; Marcy Comly; E Neufeld; Peter G Pentchev; E Joan Blanchette-Mackie; John Hanover
Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4466-71.
2001: Mei Zhang; Nancy K Dwyer; Edward B Neufeld; Dona C Love; Adele Cooney; Marcy Comly; S Patel; Hidemichi Watari; Jerome F Strauss; Peter G Pentchev; John Hanover; E Joan Blanchette-Mackie
Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes.
The Journal of biological chemistry 2001;276(5):3417-25.
2001: James M Holaska; Ben E Black; Dona C Love; John Hanover; John Leszyk; Bryce M Paschal
Calreticulin Is a receptor for nuclear export.
The Journal of cell biology 2001;152(1):127-40.
2000: Jin Ho Yoon; Dona C Love; A Guhathakurta; John Hanover; Ravi Dhar
Mex67p of Schizosaccharomyces pombe interacts with Rae1p in mediating mRNA export.
Molecular and cellular biology 2000;20(23):8767-82.
2000: G Kurys; Yutaka Tagaya; RN Bamford; John Hanover; Thomas Waldmann
The long signal peptide isoform and its alternative processing direct the intracellular trafficking of interleukin-15.
The Journal of biological chemistry 2000;275(39):30653-9.
2000: A Dace; Li Zhao; KS Park; T Furuno; N Takamura; M Nakanishi; B L West; John Hanover; S y Cheng
Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):8985-90.
2000: M D Roos; John Hanover
Structure of O-linked GlcNAc transferase: mediator of glycan-dependent signaling.
Biochemical and biophysical research communications 2000;271(2):275-80.
2000: William A Lubas; John Hanover
Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity.
The Journal of biological chemistry 2000;275(15):10983-8.
2000: Jose Bustamante; E R Michelette; John Peter Geibel; John Hanover; Timothy J McDonnell; D A Dean
Dendrimer-assisted patch-clamp sizing of nuclear pores.
Pflügers Archiv : European journal of physiology 2000;439(6):829-37.
2000: Jose Bustamante; E R Michelette; John Peter Geibel; D A Dean; John Hanover; Timothy J McDonnell
Calcium, ATP and nuclear pore channel gating.
Pflügers Archiv : European journal of physiology 2000;439(4):433-44.
2000: S Soukharev; William K Berlin; John Hanover; BD Bethke; Brian Sauer
Organization of the mouse ASGR1 gene encoding the major subunit of the hepatic asialoglycoprotein receptor.
Gene 2000;241(2):233-40.
2000: T D Sweitzer; Dona C Love; John Hanover
Regulation of nuclear import and export.
Current topics in cellular regulation 2000;36():77-94.
1999: Herman K Edskes; John Hanover; Reed Wickner
Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae.
Genetics 1999;153(2):585-94.
1999: Mill W Miller; M R Caracciolo; William K Berlin; John Hanover
Phosphorylation and glycosylation of nucleoporins.
Archives of biochemistry and biophysics 1999;367(1):51-60.
1999: John Hanover; Z Lai; G Lee; William A Lubas; S M Sato
Elevated O-linked N-acetylglucosamine metabolism in pancreatic beta-cells.
Archives of biochemistry and biophysics 1999;362(1):38-45.
1998: X G Zhu; John Hanover; Gordon L Hager; S Y Cheng
Hormone-induced translocation of thyroid hormone receptors in living cells visualized using a receptor green fluorescent protein chimera.
The Journal of biological chemistry 1998;273(42):27058-63.
1998: Dona C Love; T D Sweitzer; John Hanover
Reconstitution of HIV-1 rev nuclear export: independent requirements for nuclear import and export.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10608-13.
1998: B Fang; John Hanover; Mill W Miller
An evaluation of sialation of the nucleoporin p62.
Archives of biochemistry and biophysics 1998;357(1):95-100.
1998: M Ragano-Caracciolo; William K Berlin; Mill W Miller; John Hanover
Nuclear glycogen and glycogen synthase kinase 3.
Biochemical and biophysical research communications 1998;249(2):422-7.
1997: Yutaka Tagaya; G Kurys; T A Thies; J M Losi; Nazli Azimi; John Hanover; RN Bamford; Thomas Waldmann
Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14444-9.
1997: William A Lubas; D W Frank; Michael Krause; John Hanover
O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats.
The Journal of biological chemistry 1997;272(14):9316-24.
1996: T D Sweitzer; John Hanover
Calmodulin activates nuclear protein import: a link between signal transduction and nuclear transport.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14574-9.
1995: Jose Bustamante; A Liepins; R A Prendergast; John Hanover; H Oberleithner
Patch clamp and atomic force microscopy demonstrate TATA-binding protein (TBP) interactions with the nuclear pore complex.
The Journal of membrane biology 1995;146(3):263-72.
1995: Jose Bustamante; H Oberleithner; John Hanover; A Liepins
Patch clamp detection of transcription factor translocation along the nuclear pore complex channel.
The Journal of membrane biology 1995;146(3):253-61.
1995: Jose Bustamante; John Hanover; A Liepins
The ion channel behavior of the nuclear pore complex.
The Journal of membrane biology 1995;146(3):239-51.
1995: S M Bailer; William K Berlin; C M Starr; John Hanover
Characterization of nuclear pore protein p62 produced using baculovirus.
Protein expression and purification 1995;6(4):546-54.
1995: William A Lubas; M Smith; C M Starr; John Hanover
Analysis of nuclear pore protein p62 glycosylation.
Biochemistry 1995;34(5):1686-94.
1994: J E Murphy; John Hanover; M Froehlich; G DuBois; J H Keen
Clathrin assembly protein AP-3 is phosphorylated and glycosylated on the 50-kDa structural domain.
The Journal of biological chemistry 1994;269(33):21346-52.
1994: Jose Bustamante; A Liepins; John Hanover
Nuclear pore complex ion channels (review).
Molecular membrane biology 1994;11(3):141-50.
1994: M W Miller; John Hanover
Functional nuclear pores reconstituted with beta 1-4 galactose-modified O-linked N-acetylglucosamine glycoproteins.
The Journal of biological chemistry 1994;269(12):9289-97.
1994: F Buss; H Kent; Murray Stewart; S M Bailer; John Hanover
Role of different domains in the self-association of rat nucleoporin p62.
Journal of cell science 1994;107 ( Pt 2)():631-8.
1993: Y Miyashita; M Miller; Paul M Yen; Jeffrey M Harmon; John Hanover; S Stoney Simons
Glucocorticoid receptor binding to rat liver nuclei occurs without nuclear transport.
The Journal of steroid biochemistry and molecular biology 1993;46(3):309-20.
1992: M W Miller; John Hanover
Regulation of macromolecular traffic mediated by the nuclear pore complex.
Cell biology international reports 1992;16(8):791-8.
1992: John Hanover
The nuclear pore: at the crossroads.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(6):2288-95.
1991: M Miller; M K Park; John Hanover
Nuclear pore complex: structure, function, and regulation.
Physiological reviews 1991;71(3):909-49.
1991: B Wolff; M K Park; E Klima; John Hanover
Antibodies against the SV40 large T antigen nuclear localization sequence.
Archives of biochemistry and biophysics 1991;288(1):131-40.
1991: M D'Onofrio; M D Lee; C M Starr; M Miller; John Hanover
The gene encoding rat nuclear pore glycoprotein p62 is intronless.
The Journal of biological chemistry 1991;266(18):11980-5.
1991: C M Starr; John Hanover
A common structural motif in nuclear pore proteins (nucleoporins)
BioEssays : news and reviews in molecular, cellular and developmental biology 1991;13(3):145-6.
1991: R E Manrow; Adriana sburlati; John Hanover; SL Berger
Nuclear targeting of prothymosin alpha.
The Journal of biological chemistry 1991;266(6):3916-24.
1990: C M Starr; John Hanover
Structure and function of the nuclear pore complex: new perspectives.
BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(7):323-30.
1990: C M Starr; M D'Onofrio; M K Park; John Hanover
Primary sequence and heterologous expression of nuclear pore glycoprotein p62.
The Journal of cell biology 1990;110(6):1861-71.
1990: C M Starr; John Hanover
Glycosylation of nuclear pore protein p62. Reticulocyte lysate catalyzes O-linked N-acetylglucosamine addition in vitro.
The Journal of biological chemistry 1990;265(12):6868-73.
1989: Rolf König; G Ashwell; John Hanover
Overexpression and biosynthesis of CD4 in Chinese hamster ovary cells: coamplification using the multiple drug resistance gene.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(23):9188-92.
1988: M D'Onofrio; C M Starr; M K Park; G D Holt; R S Haltiwanger; Gerald W Hart; John Hanover
Partial cDNA sequence encoding a nuclear pore protein modified by O-linked N-acetylglucosamine.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9595-9.
1988: B Wolff; M C Willingham; John Hanover
Nuclear protein import: specificity for transport across the nuclear pore.
Experimental cell research 1988;178(2):318-34.
1988: Rolf König; G Ashwell; John Hanover
Glycosylation of CD4. Tunicamycin inhibits surface expression.
The Journal of biological chemistry 1988;263(19):9502-7.
1988: John Hanover
Intracellular transport of VSV G protein occurs in cells lacking a nuclear envelope.
Biochemical and biophysical research communications 1988;152(1):469-76.
1987: M K Park; M D'Onofrio; M C Willingham; John Hanover
A monoclonal antibody against a family of nuclear pore proteins (nucleoporins): O-linked N-acetylglucosamine is part of the immunodeterminant.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(18):6462-6.
1987: John Hanover; C K Cohen; M C Willingham; M K Park
O-linked N-acetylglucosamine is attached to proteins of the nuclear pore. Evidence for cytoplasmic and nucleoplasmic glycoproteins.
The Journal of biological chemistry 1987;262(20):9887-94.
1986: John Hanover; P D'Souza; Thomas J August; Ira Pastan; M C Willingham
Monoclonal antibodies against a glycoprotein localized in coated pits and endocytic vesicles inhibit alpha 2-macroglobulin binding and uptake.
The Journal of biological chemistry 1986;261(35):16732-7.
1985: John Hanover; L Beguinot; M C Willingham; Ira Pastan
Transit of receptors for epidermal growth factor and transferrin through clathrin-coated pits. Analysis of the kinetics of receptor entry.
The Journal of biological chemistry 1985;260(29):15938-45.
1985: L Beguinot; John Hanover; S Ito; N D Richert; M C Willingham; Ira Pastan
Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(9):2774-8.
1985: John Hanover; Ira Pastan; M C Willingham
Inhibition of phosphatidylcholine synthesis does not alter uptake of transferrin by LM fibroblasts.
Experimental cell research 1985;157(1):276-81.
1985: S Akiyama; A Fojo; John Hanover; Ira Pastan; Michael M Gottesman
Isolation and genetic characterization of human KB cell lines resistant to multiple drugs.
Somatic cell and molecular genetics 1985;11(2):117-26.
1985: R B Dickson; John Hanover; Ira Pastan; M C Willingham
Isolation of receptosomes (endosomes) from human KB cells.
Methods in enzymology 1985;109():257-71.
1984: John Hanover; M C Willingham; Ira Pastan
Kinetics of transit of transferrin and epidermal growth factor through clathrin-coated membranes.
Cell 1984;39(2 Pt 1):283-93.
1984: S Akiyama; Michael M Gottesman; John Hanover; D J Fitzgerald; M C Willingham; Ira Pastan
Verapamil enhances the toxicity of conjugates of epidermal growth factor with Pseudomonas exotoxin and antitransferrin receptor with Pseudomonas exotoxin.
Journal of cellular physiology 1984;120(3):271-9.
1984: M C Willingham; John Hanover; R B Dickson; Ira Pastan
Morphologic characterization of the pathway of transferrin endocytosis and recycling in human KB cells.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(1):175-9.
1983: John Hanover; J E Rudick; M C Willingham; Ira Pastan
Alpha 2-macroglobulin binding to cultured fibroblasts: identification by affinity chromatography of high-affinity binding sites.
Archives of biochemistry and biophysics 1983;227(2):570-9.
1983: R B Dickson; John Hanover; M C Willingham; Ira Pastan
Prelysosomal divergence of transferrin and epidermal growth factor during receptor-mediated endocytosis.
Biochemistry 1983;22(24):5667-74.
1983: R B Dickson; L Beguinot; John Hanover; N D Richert; M C Willingham; Ira Pastan
Isolation and characterization of a highly enriched preparation of receptosomes (endosomes) from a human cell line.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(17):5335-9.
1983: John Hanover; S Cheng; M C Willingham; Ira Pastan
alpha 2-Macroglobulin binding to cultured fibroblasts. Solubilization and partial purification of binding sites.
The Journal of biological chemistry 1983;258(1):370-7.
1983: John Hanover; M C Willingham; Ira Pastan
Receptor-mediated endocytosis of alpha 2-macroglobulin: solubilization and partial purification of the fibroblast alpha 2-macroglobulin receptor.
Annals of the New York Academy of Sciences 1983;421():410-23.
1982: John Hanover; J Elting; G R Mintz; W J Lennarz
Temporal aspects of the N- and O-glycosylation of human chorionic gonadotropin.
The Journal of biological chemistry 1982;257(17):10172-7.
1982: John Hanover; W J Lennarz
Transmembrane assembly of N-linked glycoproteins. Studies on the topology of saccharide synthesis.
The Journal of biological chemistry 1982;257(6):2787-94.
1981: John Hanover; W J Lennarz
Transmembrane assembly of membrane and secretory glycoproteins.
Archives of biochemistry and biophysics 1981;211(1):1-19.
1980: C G Glabe; John Hanover; W J Lennarz
Glycosylation of ovalbumin nascent chains. The spatial relationship between translation and glycosylation.
The Journal of biological chemistry 1980;255(19):9236-42.
1980: John Hanover; W J Lennarz; J D Young
Synthesis of N- and O-linked glycopeptides in oviduct membrane preparations.
The Journal of biological chemistry 1980;255(14):6713-6.
1980: John Hanover; W J Lennarz
N-Linked glycoprotein assembly. Evidence that oligosaccharide attachment occurs within the lumen of the endoplasmic reticulum.
The Journal of biological chemistry 1980;255(8):3600-4.
1979: John Hanover; W J Lennarz
The topological orientation of N,N'-diacetylchitobiosylpyrophosphoryldolichol in artificial and natural membranes.
The Journal of biological chemistry 1979;254(18):9237-46.